CN102258445B - SOD (superoxide dismutase) collagen peptide facial-beautification anti-aging agent - Google Patents

SOD (superoxide dismutase) collagen peptide facial-beautification anti-aging agent Download PDF

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CN102258445B
CN102258445B CN201110197534A CN201110197534A CN102258445B CN 102258445 B CN102258445 B CN 102258445B CN 201110197534 A CN201110197534 A CN 201110197534A CN 201110197534 A CN201110197534 A CN 201110197534A CN 102258445 B CN102258445 B CN 102258445B
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陈俊杰
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Abstract

The invention discloses an SOD (superoxide dismutase) collagen peptide facial-beautification anti-aging agent which is mainly prepared from 1 million active units of plant SOD, 93g of collagen polypeptide, 1g of hyaluronic acid and 6g of pearl powder. The invention can effectively postpone aging of the human body; when people take SOD collagen polypeptide once or twice a day, the SOD collagen polypeptide can bind and connect cells of the human body into organs and tissues, so that the human body has the functions of defense, supporting, nutrition protection and the like; when connective tissues perform the metabolic function together with muscles or organs, the connective tissues can deliver the SOD, collagen polypeptide and other nutritional ingredients, and oxygen into cells, and remove harmful substances from the cells, thereby accelerating the metabolism in vivo; and therefore, the invention is applicable to repair and regeneration of human body tissues, thereby achieving the goals of facial beautification and anti-aging.

Description

The U.S. face antidotal agent of SOD collagen peptide
Technical field
The present invention relates to the U.S. face antidotal agent of SOD collagen peptide.
Background technology
With advancing age; Covalent crosslink between the procollagen triple helical forms more and more; Cause soluble collagen to reduce, the iuntercellular mucopolysaccharide is also reduced, this situation at first occurs in face, neck, hands etc. and is exposed in the air for a long time; Receive the position of sunlight middle-ultraviolet lamp irradiation; Cause collagen fibers of skin Shu Bianzhi, skin elasticity variation, cause the fibrous fracture, lipoatrophy, sweat gland of corium and smegma to reduce, cutis laxa, coarse, dry and cracked, lipofuscin are obviously increased mottle occurs and a series of catabiosis such as other local pigments sexually revise, wrinkle; After people in middle age, along with the increase at age, intravital SOD is active to descend on the other hand, and superfluous free radical appears in the generation of free radical and removing disequilibrium, causes lipid peroxidation, makes the biomembrane loss of function, causes cell viability to descend, and causes body aging.
Retain youthful vitality, though the method for handsome beauty is a lot, like Chinese patent medicine, health-care medicament, importing injection, cosmetic etc. all have certain effect, and all are not up to expectations.
Summary of the invention
The present invention is intended to overcome the deficiency that existing Chinese patent medicine imports injection, cosmetics skin protection etc., provides a kind of U.S. face crease-resistant health product.
In order to achieve the above object, the present invention adopts following technical scheme: the U.S. face antidotal agent of a kind of SOD collagen peptide comprises following composition: plant SOD 1,000,000 active units, collagen polypeptide 93 grams, hyaluronic acid 1 gram, Margarita powder 6 grams.
Further, the U.S. face antidotal agent of described SOD collagen peptide also contains Radix Ginseng total saponins extract 1 gram, Cordyceps powder 0.2 gram.
Further, the U.S. face antidotal agent of described SOD collagen peptide also contains 50 milligrams on selenium.
The U.S. face antidotal agent of SOD collagen peptide of the present invention is selected natural plants SOD for use, collagen protein polypeptide, hyaluronic acid, Margarita powder etc.; From A. activating cell function, B. improves immunity, and C. keeps cornea transparent; D. alleviate arthralgia, E. keeps bone health, and F. keeps hair healthy moist; G. human body harmful's free radical is removed in the beautifying and antisenility aspect of waiting for a long time, and makes the young attitude of each functional recovery of human body.
Natural plants SOD of the present invention; Compositions such as collagen protein polypeptide, hyaluronic acid, Margarita powder can directly work to flight against senium of human body, and compositions such as Radix Ginseng total saponins extract, Cordyceps powder, selenium then play anti-aging effects through regulating physical function indirectly.The double effects that thereby reaching effects a permanent cure takes stopgap measures.
Enforcement of the present invention can be adopted conventional packing, selects for use the aluminium foil irradiation sterilization to form, once a day to twice, and each 1 bag, every bag 3-5 gram, warm water takes, and is all-ages.
Every day, 1~2 SOD collagen protein polypeptide can bind the human body self cell, connected to organ and tissue, had functions such as defence supportive protection nutrition; When connective tissue is carried out metabolic function with muscle or organ; It can remove harmful substance, the acceleration bodies intracellular metabolic again from cell with nutritional labeling such as SOD and collagen polypeptide and oxygen delivery in cell; Therefore be suitable for tissue repairing and regeneration, thereby reach the purpose of beautifying and anti-aging.
The specific embodiment
Embodiment 1
The U.S. face antidotal agent of SOD collagen peptide of the present invention contains following component: plant SOD 1,000,000 active units, collagen polypeptide 93 grams, hyaluronic acid 1 gram, Margarita powder 6 grams.
Above-mentioned each composition mix homogeneously gets final product.
Wherein, plant SOD is used for catalysis ultra-oxygen anion free radical (O2-) dismutation reaction takes place, and it plays crucial effects to the oxidation of balance body and antioxidant system, release radical damage.SOD level and free-radical contents are negative correlation in the human body, and the height of its level can reflect the content of free radical in the body indirectly.Secondly SOD is widely distributed in each tissue of whole body, and is the highest with liver content, be kidney and erythrocyte, erythrocyte since the function of carrying oxygen be exposed in the environment of oxygen enrichment, SOD that need be a large amount of is to eliminate issuable free radical.
SOD is to the mechanism of action of human body:
1.SOD can stop leukocyte to descend; When the leukocyte famine, treat than can recover faster and better with SOD with 17-hydroxy-11-dehydrocorticosterone (AcTH), SOD can make bone marrow produce leukocyte; And cortin only uses the leukocyte in the human body blood bank to get into blood circulation; Be helpless to the increase of leukocyte itself, go back immunosuppressant simultaneously, SOD can improve immunity.
2, SOD can remove free radical.But SOD catalysis O2-or HO2-are disproportionated into O2 or H2O2 with it.Ozone and NO2 cell membrane are poisoned, and ozone is attacked PNA, DNA, under NO2 and action of ultraviolet radiation, generate imino group oxygen base, nitre oxygen base free radical, and having a suck of cigarette has 1,000,000 free radicals, the alkoxy free group in the flue gas etc.1985 Rome like the 4th the free radical biological theory seminar in the world of opening on, generally acknowledge that from the science of more than 120 countries are consistent SOD is " scavenger of human body waste "
3, SOD can remove free radical protection cell membrane.
4, O2-causes that with cardiac muscle, brain, ischemia of lung damage is relevant, handles with SOD and can reduce the infraction block size that coronary occlusion produces.
5, SOD can protect the damage because of free radical of capillary endothelium and parenchyma.
6, SOD can stop the intestinal mucosal injury that is caused by hydroxy radical.
7, because the O2-damage produces the pancreas island β cell of insulin, SOD can protect the β cell.
8, because free radical increases, cause the crosslinked generation cataract of ophthalmic α and β crystalline protein, SOD can slow down protein-crosslinking.
9, some controls the cancer thing, attacks mycin, amycin, Antibiotic-4761, bleomycin etc. like silk, all comes kill cancer cell with the active oxygen that produces, and also good cell is produced simultaneously and poisons.SOD can protect cell and exempt from toxicity of biological active oxygen.
10, radiation can make DNA depolymerization, fracture, base destruction, crosslinked, lipid peroxidation, makes the erythrocyte damage, makes hematopoietic stem cell injuries; SOD can make above-mentioned phenomenon alleviate; SOD shields, so as the curative of treatment tumour radiotherapy disease syndrome, can make acute and the chronic inflammation disease alleviates.
11, nineteen eighty-three Nissen test points out that people's * * has the SOD activity, and it and motility of sperm have direct relation, and SOD plays protection to sperm and is used as, and the SOD of Placenta Hominis and Cat enzymatic activitys such as (catalases) raise during gestation, have protected Placenta Hominis and fetus effectively
12, after Denham Harman in 1956 proposes old and feeble oxyradical theory; The focus that free radical scavenger has just become health care to lengthen the life; Like the VC of antioxidant, VA, VE, glutathion etc., therefore, the inhibitor in the free-radical generating process ought to be powerful long-lived protective agent; The extremely important scavenger SOD enzyme of free radical has become the health care focus of lengthening the life naturally.So is undisputed with the laurel of " 21st century health care gold " to SOD.
13, free radical makes the unsaturated fatty acid peroxidating; Generate malonaldehyde at last through a series of biochemical reactions (unsaturated fatty acid+radical initiator → free radical is drawn oxygen and become fatty acid peroxy radical → from unsaturated fatty acid, draw hydrogen again to generate more polyradical); Again with protein in amine groups should with protein cross, generating pigment becomes lipofuscin.These pigments have greatly destroyed the cells physiological function, along with the age increases, and these circular or oval-shaped pigment enlarged diameter; Be deposited in heart, the neurocyte, be deposited in the skin, become senile plaque, so remove the fabulous SOD enzyme of free radical; Become dispel old class, skin whitening remove the speckle enzyme; Its all benefits are that people can't express with language, and oral SOD effect is the most obvious, in cosmetics, also is applied well.
14, SOD can block β one 4 amyloid (β-AP can produce free radical and lipid mistake, lesion wire plastochondria for β-AP) to antiotasis and endothelial injury, the glutamic acid of protection brain and the function of glucose transporter.
Collagen polypeptide is of high nutritive value, and the protection gastric mucosa prevents Peptic Ulcers.Suppress increased blood pressure, promote ossification, prevention of osteoporosis promotes the skin collagen metabolism, plays the effect of beauty treatment, and various joint disease are had excellent prevention and therapeutical effect.Be used for prevention and bone diseases such as treatment of arthritis and osteoporosis, promote the absorption of calcium.Collagen polypeptide is to keep the indispensable important component of health normal activity.Simultaneously also be to make health keep young, prevent aged material.In addition, all right prevent disease of collagen polypeptide is improved body constitution, and is all helpful to beauty treatment and health.
Hyaluronic acid (Hyaluronic acid, HA) has another name called Hyaluronic acid, be a kind of acid mucopolysaccharide, the ophthalmology professor Meyer of Columbia Univ USA in 1934 etc. at first isolate this material from bovine vitreous body.Hyaluronic acid demonstrates multiple important physical function with its distinctive molecular structure and physicochemical property in body, like lubricated joint, regulate the permeability of blood vessel wall, regulates protein, and Water-Electrolyte diffusion and running promote wound healing etc.Particularly importantly; Hyaluronic acid has special water retention; It is the best material of finding at present of occurring in nature moisture retention; (for example: the water-soluble fluid power of 2% pure hyaluronic acid keeps 98% moisture securely for Natural moisturizing factor, NMF to be called as ideal nature moisturizing factor.Hyaluronic acid is a kind of multi-functional substrate, and hyaluronic acid (hyaluronic acid) HA is distributed widely in the partes corporis humani position.Wherein skin also contains a large amount of hyaluronic acids.Ripe and the ageing process of human skin also changes along with hyaluronic content and metabolism; It can improve the skin-nourishing metabolism; Making that skin is tender, smooth, wrinkle removing, increase elasticity, prevent aging, is again the good transdermal absorption enhancer when preserving moisture.Be used with other nutritional labelings, can play the better effect that promotes alimentation.
Margarita powder has following effect:
A but delaying human body caducity.
Two, liver heat removing and eyesight improving.Margarita is taken away Liver Channel orally, and ophthalmic is controlled in external, pearl eyesight.But from infant clothes vision protection.
Three, the spring is preserved in skin care.Clothes make the whole body fragile muscle and skin white for a long time.
Four, removing toxic substances and promoting granulation.As too much taking orally and can stop blooding rapidly, so do not take through the normal person's menstrual phase of amount through amount.
Five, replenish the calcium.
Six, the effect of human body ph values such as adjustment gastric acid hematic acid uric acid, Margarita is alkalescence, clothes must make blood be alkalescence for a long time, be not afraid of mosquito to improve skin immune function controlling, in can be good for the stomach with gastric acid, have anti-allergic effects because of increasing the blood calcium event.Analyzing Margarita clothes of a specified duration from chemical terms must have good health and a long life.
Seven, Margarita goes into heart channel.Tranquilizing mind, yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and expectorant is weighed down in heat clearing away, and " the peace soul is ended seminal emission, and nebulousurine is separated pox and treated poison, and " clothes can keep a cool head for a long time, and the quality of sleep is improved, and medical research is useful to heart disease.
Eight, sooner or later the buccal Margarita powder can be controlled oral disease such as dispute is festered, and pharyngitis, teeth inflammation etc. all have antiinflammation, also have the tooth protection effect.
Nine, the women is conceived, and Margarita powder is taken in suckling, and the fetus baby is had the acceleration normal development of skeleton, increases the effect of intelligence, and skin is thin in vain in addition.
Ten, Margarita powder deoils, and removes antiperspirant, and it is prosperous excessively to suppress sebum secretion, can effectively block ultraviolet, has the effect that the sun-proof anti-width of cloth is penetrated.
Embodiment 2
The U.S. face antidotal agent of described SOD collagen peptide also contains Radix Ginseng total saponins extract 1 gram, Cordyceps powder 0.2 gram, and all the other are identical with embodiment 1.
Wherein, Radix Ginseng total saponins extracts according to following method for distilling, also can buy from existing commercial sources.Described method for distilling is made up of following processing step:
A, ginseng material soak and decoct
(A) be 1: 8~16 in the ginseng material, to add entry by the ratio of weight and number of ginseng material and water, soak at room temperature 0.5~2 hour, then, the mixture heated to 70 ℃~100 ℃ with both is incubated 1~3 hour, afterwards, residue obtained liquid;
(B) be 1: 6~10 in the slag that above-mentioned steps (A) leaches, to add entry by the ratio of weight and number of said ginseng material and tap water, and, be incubated 1~2.5 hour both mixture heated to 70 ℃~100 ℃, afterwards, residue obtained liquid;
(C) be 1: 6~8 in the slag that above-mentioned steps (B) leaches, to add entry by the ratio of weight and number of said ginseng material and water, and, be incubated 1~1.5 hour both mixture heated to 70 ℃~100 ℃, afterwards, residue obtained liquid;
B, liquid concentration, the liquid mixing that will produce through said each work step (A), (B), (C) is the back concentrating under reduced pressure together, is to end at 1~3: 1 until the ratio of its weight and said ginseng material weight;
The macroporous resin column of liquid after C, absorption, eluting make and concentrate after through activated processing; Saponin in the liquid being adsorbed by resin column, and discard effluent, is that 0.1~1: 1 ratio is taken the distilled water flushing resin column in distilled water and the ratio that concentrates the volume of back liquid again; Discard effluent; The use concentration that continues is 50~70% ethanol cleaning resin column, and absorption saponin is on it ended by complete eluting, and the collection eluent.
The ethanol that D, finished product reclaim, dried recovered operation C collects eluent after the remaining material drying, can obtain the Radix Ginseng total saponins finished product.
Radix Ginseng total saponins has multiple effect, comprises anti-aging effects.The lipid peroxidation that the Radix Ginseng total saponins extract has stronger antioxidation and suppresses human body, thus blocking-up is of value to the slow down aging of body by basic peroxidization.
The Cordyceps powder, the Cordyceps powder that the present invention is used is got dried Cordyceps grind into powder and is got final product.Owing to do not pass through any processing, make the nutritional labeling of Cordyceps wait until good reservation.
Cordyceps has following function:
1, regulates the function of immune system immune system and be equivalent to the army in the human body, internally resist tumor, remove aging, downright bad cell tissue, externally resist infected by microbes such as virus, antibacterial.The tumor cell that human body all possibly occur suddenling change every day.The normal human body of function of immune system can be escaped the misfortune of tumor, and the people that function of immune system goes wrong but possibly develop into tumor.Cordyceps similarly is in the adjustment volume to immune effect, makes it be in optimum state.It can increase immune system cell, organize quantity, and enhancing antibody produces, increase engulf, killer cell quantity, its function that strengthens, can turn down the function of some immunocyte again.
2, Cordyceps extract has clear and definite inhibition, an effect of killing tumor cell external, contains cordycepin in the Cordyceps, and it is the main component of performance antitumor action.
3, Cordyceps can improve body energy factory--mitochondrial energy, improve the body tolerance to cold, and lessen fatigue.
4, Cordyceps can improve the heart hypoxia-bearing capability, reduces the consumption of heart to oxygen, arrhythmia.
5, Cordyceps can alleviate the damage of noxious substance to liver.In addition,, strengthen anti-virus ability, to viral hepatitis performance advantageous effect through regulating immunologic function.
6, Cordyceps has expansion bronchus, relievings asthma, eliminates the phlegm, prevents emophysematous effect.
7, Cordyceps can alleviate the nephropathy of chronic disease, improves renal function, alleviates the infringement of toxicant to kidney.
8, Cordyceps can strengthen bone marrow generation platelet, erythrocyte and leukocytic ability.
9, Cordyceps can reduce cholesterol and the triglyceride in the blood, improves the high density lipoprotein favourable to human body, alleviates atherosclerosis.
10, other Cordyceps also have direct antiviral, regulate effects such as central nervous system function, adjusting sexual function, and Cordyceps can play so comprehensively health-care effect to human body.
Embodiment 3
The U.S. face antidotal agent of described SOD collagen peptide also contains 50 milligrams on selenium, and all the other are identical with embodiment 2.
Selenium is one of trace element of needed by human; Scarce selenium can cause the high morbidity of kind surplus cancer, cardiovascular and cerebrovascular disease, hypertension syndrome, hepatopathy, diabetes, gastrointestinal disease, the asthma etc. 40, and the selenium in the micro elements needed by human is the active component of glutathione peroxidase.This enzyme can decomposer inner lipid peroxide, has antioxidation, the protection body is avoided oxidative damage, just protects biomembrane to be without prejudice.Selenium can hinder the metabolic response of carcinogen in vivo process, stops the metabolism of chemical carcinogen and the bonding of blocking-up and DNA, stops the structural mutation of DNA spiral, the growth of anticancer.Selenium can also react by activate immunity, improves body's immunological function.Be in the environment due to the carcinogen invasion under many circumstances, and selenium can be resisted these carcinogen, make it can not be carcinogenic; The carcinogen that has (like Benzpyrene) generates behind the intermediate product carcinogenic in human body, and selenium can suppress the generation of this intermediate product, can promote the decomposition of this product again, its carcinogenic effect of two-way inhibition; Another dangerous approach of suffering from tumor is the free radical that the human body intracellular metabolic produces; Be commonly called as rubbish in the body; Can not in time clear up the membrane structure that to damage cell and tend to canceration; Selenium is the street cleaner of the interior rubbish of these bodies just, and it is removed free radical through glutathione peroxidase (intravital strong oxidizer) and protects cell membrane, prevents canceration.In the treatment like the discovery patient low selenium appears, suitable external source Selenium Supplement,, can improve patient's body's immunity, strengthen giving protection against cancer and antitumaous effect.

Claims (1)

1. the U.S. face antidotal agent of a SOD collagen peptide, composed of the following components: plant SOD 1,000,000 active units, collagen polypeptide 93 grams, hyaluronic acid 1 gram, Margarita powder 6 grams, Radix Ginseng total saponins extract 1 gram, Cordyceps powder 0.2 gram,
Wherein, described Radix Ginseng total saponins extracts according to following method for distilling:
A, ginseng material soak and decoct:
(A) ratio of weight and number by ginseng material and water is 1: 8-16 adds entry in the ginseng material, soak at room temperature 0.5 ~ 2 hour, and then, the mixture heated to 70 ℃ ~ 100 ℃ with both is incubated 1-3 hour, afterwards, residue obtained liquid;
(B) be 1: 6 ~ 10 in the slag that above-mentioned steps (A) leaches, to add entry by the ratio of weight and number of said ginseng material and tap water, and, be incubated 1 ~ 2.5 hour both mixture heated to 70 ℃ ~ 100 ℃, afterwards, residue obtained liquid;
(C) be 1: 6 ~ 8 in the slag that above-mentioned steps (B) leaches, to add entry by the ratio of weight and number of said ginseng material and water, and, be incubated 1 ~ 1.5 hour both mixture heated to 70 ℃ ~ 100 ℃, afterwards, residue obtained liquid;
B, liquid concentration: the liquid mixing that will be respectively produce through said each work step (A), (B), (C) is the back concentrating under reduced pressure together, is to end at 1 ~ 3: 1 until the ratio of its weight and said ginseng material weight;
C, absorption, eluting: the macroporous resin column after making liquid after concentrating through activated processing; Saponin in the liquid being adsorbed by resin column, and discard effluent, is that 0.1 ~ 1: 1 ratio is taken the distilled water flushing resin column in distilled water and the ratio that concentrates the volume of back liquid again; Discard effluent; The use concentration that continues is 50 ~ 70% ethanol cleaning resin column, makes till the absorption complete eluting of saponin quilt on it, and collects eluent;
D, finished product reclaim, drying: reclaim the ethanol that above-mentioned operation C collects eluent, after the remaining material drying, can obtain the Radix Ginseng total saponins finished product.
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