CN102228563B - Traditional Chinese medicine preparation for treating paroxysmal nocturnal hemoglobinuria - Google Patents

Traditional Chinese medicine preparation for treating paroxysmal nocturnal hemoglobinuria Download PDF

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CN102228563B
CN102228563B CN2011101693687A CN201110169368A CN102228563B CN 102228563 B CN102228563 B CN 102228563B CN 2011101693687 A CN2011101693687 A CN 2011101693687A CN 201110169368 A CN201110169368 A CN 201110169368A CN 102228563 B CN102228563 B CN 102228563B
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chinese medicine
radix
traditional chinese
paroxysmal nocturnal
nocturnal hemoglobinuria
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CN2011101693687A
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CN102228563A (en
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莫忆鸣
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating paroxysmal nocturnal hemoglobinuria, which is prepared from the following traditional Chinese medicine raw materials in percentage by weight: 28-32g of red ginseng, 13-17g of processed Radix Rehmanniae, 7-12g of medlar, 28-32g of Codonopsis pilosula, 7-12g of Poria cocos, 7-12g of white atractylodes rhizome, 10-14g of angelica, 7-12g of donkey-hide gelatin, 28-32g of hairyvein agrimony, 13-17g of field thistle, 7-12g of red paeony root, 6-8 g of licorice and 5-7 of Chinese date. The preparation of the traditional Chinese medicine preparation comprises the following steps of: soaking the traditional Chinese medicines in a casserole for 2 hours, decocting on slow fire for 40 minutes after water boiling, collecting 200ml of filtrate, adding water to the residues, decocting on slow fire for 1 hour after water boiling, collecting about 200ml of filtrate, melting donkey-hide gelatin in the filtrate, combining the filtrates, and finally uniformly stirring. The traditional Chinese medicine preparation is taken twice a day, respectively in the morning and at night, and 200 ml each time. The traditional Chinese medicine preparation is a soup preparation prepared from traditional Chinese medicine raw materials, and has the advantages of significant treatment effect, no toxic or side effect and very low recurrence rate after being taken by patients.

Description

A kind of Chinese medicine of treating paroxysmal nocturnal hemoglobinuria
Technical field
The present invention relates to Chinese medicine, is a kind of Chinese medicine of main treatment paroxysmal nocturnal hemoglobinuria.
Background technology
The paroxysmal nocturnal hemoglobinuria patient tangible symptom of performance usually has fever, lumbago, stomachache and general malaise sense etc.; Because its cause of disease is to have in the blood vessel to exceed normal haemolysis; This haemolysis possibly cause bigger misery to the patient by medicine, chemical substance or by due to the multiple reasons such as animal bite.At present, the conventional therapy of treatment paroxysmal nocturnal hemoglobinuria is for alleviating anemia or reducing the haemolysis outbreak, for example: blood transfusion, androgen, chalybeate, folic acid, adrenocortical hormone, dextran, sodium bicarbonate, prednisone, antioxidant etc.But these side effects of pharmaceutical drugs are very big, and curative effect is not good enough, patient Yi Fanfu outbreak.
Summary of the invention
The objective of the invention is, a kind of Chinese medicine of treating paroxysmal nocturnal hemoglobinuria is provided, it adopts raw material of Chinese medicine to process decoction, and it is evident in efficacy that the patient takes the back, nontoxic secondary the use, and relapse rate is extremely low.
The present invention is for realizing above-mentioned purpose; Realize through following technical scheme: a kind of Chinese medicine of treating paroxysmal nocturnal hemoglobinuria, process by following raw material of Chinese medicine: Radix Ginseng Rubra 28-32g, Radix Rehmanniae Preparata 13-17g, Fructus Lycii 7-12g, Radix Codonopsis 28-32g, Poria 7-12g, Rhizoma Atractylodis Macrocephalae 7-12g, Radix Angelicae Sinensis 10-14g, Colla Corii Asini 7-12g, Herba Agrimoniae 28-32g, Herba Cirsii 13-17g, Radix Paeoniae Rubra 7-12g, Radix Glycyrrhizae 6-8g, Fructus Jujubae 5-7 piece.
Described a kind of Chinese medicine of treating paroxysmal nocturnal hemoglobinuria is processed by following raw material of Chinese medicine: 7 pieces of Radix Ginseng Rubra 32g, Radix Rehmanniae Preparata 17g, Fructus Lycii 12g, Radix Codonopsis 32g, Poria 12g, Rhizoma Atractylodis Macrocephalae 12g, Radix Angelicae Sinensis 14g, Colla Corii Asini 12g, Herba Agrimoniae 2g, Herba Cirsii 17g, Radix Paeoniae Rubra 12g, Radix Glycyrrhizae 8g, Fructus Jujubae.
Described a kind of Chinese medicine of treating paroxysmal nocturnal hemoglobinuria is processed by following raw material of Chinese medicine: 5 pieces of Radix Ginseng Rubra 28g, Radix Rehmanniae Preparata 13g, Fructus Lycii 7g, Radix Codonopsis 28g, Poria 7g, Rhizoma Atractylodis Macrocephalae 7g, Radix Angelicae Sinensis 10g, Colla Corii Asini 7g, Herba Agrimoniae 28g, Herba Cirsii 13g, Radix Paeoniae Rubra 7g, Radix Glycyrrhizae 6g, Fructus Jujubae.
The traditional Chinese medical science thinks that the pathology of paroxysmal nocturnal hemoglobinuria is by due to the asthenia of both the spleen and kidney.Because temper is lost empty, blood loses in having under one's command, and the bladder of making a bet is sent out and is hemoglobinuria, deficiency of kidney-essence, the passive and anemia of bloodization, deficiency of kidney yin, deficiency-fire stirring up, damage blood network and cause hematuria.Therefore, Chinese medicine of the present invention is chosen the raw material of Chinese medicine combination according to hemoglobinuric pathology, to reach the effect of treating both the principal and secondary aspects of a disease.Radix Ginseng Rubra in the raw material of Chinese medicine according to the invention is used for invigorating qi and benefiting blood, Yin-nourishing and body fluid promoting; Radix Rehmanniae Preparata be used to enrich blood YIN nourishing, vital essence replenishing and marrow benifiting, Fructus Lycii is used for the nourishing kidney QI invigorating; Radix Codonopsis is used for invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting; Poria is used for the spleen invigorating mind calming; The Rhizoma Atractylodis Macrocephalae is used for invigorating the spleen and benefiting QI; Radix Angelicae Sinensis is used to enrich blood, invigorate blood circulation; Colla Corii Asini is moisturized hemostasis with the YIN nourishing of enriching blood; Herba Agrimoniae is used for astringing to arrest bleeding, tonify deficiency dysentery relieving, parasite killing detoxifcation; Herba Cirsii is used for promoting blood circulation and detoxication; Radix Paeoniae Rubra is used for blood circulation promoting and blood stasis dispelling, clearing away heat and cooling blood; Radix Glycyrrhizae is used for spleen reinforcing, detoxifcation, coordinating the actions of various ingredients in a prescription; Fructus Jujubae is used to strengthen the spleen and stomach, benefiting QI and nourishing blood, the mediation property of medicine.Above-mentioned all medicine combinations are used for replenishing QI to invigorate the spleen, the kidney invigorating and essence nourishing, blood-supplementing blood-nourishing, and hemostasis, blood circulation promoting and blood stasis dispelling, the QI invigorating invigorating middle warmer, thus paroxysmal sleep property hemoglobinuria reached the effect of treating both the principal and secondary aspects of a disease.
The raw material of Chinese medicine of the present invention is the traditional drugs that has no side effect, and uses proof without any side effects for many years.
37 routine paroxysmal nocturnal hemoglobinuria patients are treated in clinical practice of the present invention, and obvious effective rate is 100%, and cure rate is 89%.Clinical physical data shows that the patient has the minority erythrocyte through hospital's urine specimen centrifuge post precipitation inspection; The urine benzidine test is positive, gets rid of the MG Myoglobin HMYO cell simultaneously and with symptoms such as fever, lumbago, stomachache, takes Chinese medicine decoction of the present invention; One day potion; Decocting merges medicinal liquid two times, sooner or later respectively once, and each 200ml.Produce effects person is 100% after taking medicine 2 days, and clinical symptom disappearance person is 73% after taking medicine 5 days, and clinical symptom disappearance person is 89% after taking medicine 10 days, and tracing observation is not recurrence more than 6 months.
Model case:
1, appoint XX, the man, 46 years old, the oral account examination in hospital was a paroxysmal nocturnal hemoglobinuria when went to a doctor in April, 2007.With weak waist stomachache, anemia.The clothes Western medicine is transfused blood once simultaneously, takes a turn for the better the back recurrence of 2 week of drug withdrawal, oral Chinese medicine of the present invention produce effects after 2 days; Weak transference cure after taking medicine 5 days, the waist colic symptoms alleviates, and after taking medicine 9 days, clinical symptoms all disappears; Examination in hospital hematochrome 138g/L, urine erythrocyte disappears, and urine is negative.Tracing observation is not recurrence so far.
Preparation method of Chinese medicine according to the invention is following: raw material of Chinese medicine of the present invention is pressed Radix Ginseng Rubra, Radix Rehmanniae Preparata, Fructus Lycii, Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Herba Agrimoniae, Herba Cirsii, Radix Paeoniae Rubra, Radix Glycyrrhizae, Fructus Jujubae insert in the water and soaked 1-2 hour; Boiling back 30-50 at a simmer minute is filtrated about 200 milliliters, and medicinal residues were fried in shallow oil 1-1.5 hour after adding the water boiling; Filtrate about 200 milliliters; After twice filtrating merges Colla Corii Asini is inserted molten in the medicinal liquid, after stirring, sooner or later respectively obey 200 milliliters.Period in a medicine avoids pungent food, cold and cool food.
The specific embodiment
A kind of Chinese medicine of treating paroxysmal nocturnal hemoglobinuria of the present invention is processed by following raw material of Chinese medicine: Radix Ginseng Rubra 28-32g, Radix Rehmanniae Preparata 13-17g, Fructus Lycii 7-12g, Radix Codonopsis 28-32g, Poria 7-12g, Rhizoma Atractylodis Macrocephalae 7-12g, Radix Angelicae Sinensis 10-14g, Colla Corii Asini 7-12g, Herba Agrimoniae 28-32g, Herba Cirsii 13-17g, Radix Paeoniae Rubra 7-12g, Radix Glycyrrhizae 6-8g, Fructus Jujubae 5-7 piece.
A kind of raw material of Chinese medicine of treating paroxysmal nocturnal hemoglobinuria according to the invention can have multiple combination:
1, Radix Ginseng Rubra 30g, Radix Rehmanniae Preparata 15g, Fructus Lycii 9g, Radix Codonopsis 30g, Poria 9g, Rhizoma Atractylodis Macrocephalae 9g, Radix Angelicae Sinensis 12g, Colla Corii Asini 9g, Herba Agrimoniae 30g, Herba Cirsii 15g, Radix Paeoniae Rubra 9g, Radix Glycyrrhizae 7g, Fructus Jujubae are 6 pieces.
2, Radix Ginseng Rubra 32g, Radix Rehmanniae Preparata 17g, Fructus Lycii 12g, Radix Codonopsis 32g, Poria 12g, Rhizoma Atractylodis Macrocephalae 12g, Radix Angelicae Sinensis 14g, Colla Corii Asini 12g, Herba Agrimoniae 32g, Herba Cirsii 17g, Radix Paeoniae Rubra 12g, Radix Glycyrrhizae 8g, Fructus Jujubae are 7 pieces.
3, Radix Ginseng Rubra 28g, Radix Rehmanniae Preparata 13g, Fructus Lycii 7g, Radix Codonopsis 28g, Poria 7g, Rhizoma Atractylodis Macrocephalae 7g, Radix Angelicae Sinensis 10g, Colla Corii Asini 7g, Herba Agrimoniae 28g, Herba Cirsii 13g, Radix Paeoniae Rubra 7g, Radix Glycyrrhizae 6g, Fructus Jujubae are 5 pieces.
The Chinese medicine of above-mentioned various combinations is all produced as follows: Radix Ginseng Rubra, Radix Rehmanniae Preparata, Fructus Lycii, Radix Codonopsis, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Herba Agrimoniae, Herba Cirsii, Radix Paeoniae Rubra, Radix Glycyrrhizae, Fructus Jujubae are inserted in the marmite soaked 2 hours; Filtrate 200 milliliters in 40 minutes at a simmer of water boiling back, medicinal residues add 1 hour at a simmer of water boiling back; Filtrate about 200 milliliters; Colla Corii Asini is inserted molten in the filtrating, stir after twice filtrating merges, sooner or later respectively obey 200 milliliters.

Claims (3)

1. Chinese medicine of treating paroxysmal nocturnal hemoglobinuria is characterized in that: processed by following raw material of Chinese medicine: Radix Ginseng Rubra 28-32g, Radix Rehmanniae Preparata 13-17g, Fructus Lycii 7-12g, Radix Codonopsis 28-32g, Poria 7-12g, Rhizoma Atractylodis Macrocephalae 7-12g, Radix Angelicae Sinensis 10-14g, Colla Corii Asini 7-12g, Herba Agrimoniae 28-32g, Herba Cirsii 13-17g, Radix Paeoniae Rubra 7-12g, Radix Glycyrrhizae 6-8g, Fructus Jujubae 5-7 piece.
2. a kind of Chinese medicine of treating paroxysmal nocturnal hemoglobinuria according to claim 1 is characterized in that: processed by following raw material of Chinese medicine: 7 pieces of Radix Ginseng Rubra 32g, Radix Rehmanniae Preparata 17g, Fructus Lycii 12g, Radix Codonopsis 32g, Poria 12g, Rhizoma Atractylodis Macrocephalae 12g, Radix Angelicae Sinensis 14g, Colla Corii Asini 12g, Herba Agrimoniae 2g, Herba Cirsii 17g, Radix Paeoniae Rubra 12g, Radix Glycyrrhizae 8g, Fructus Jujubae.
3. a kind of Chinese medicine of treating paroxysmal nocturnal hemoglobinuria according to claim 1 is characterized in that: processed by following raw material of Chinese medicine: 5 pieces of Radix Ginseng Rubra 28g, Radix Rehmanniae Preparata 13g, Fructus Lycii 7g, Radix Codonopsis 28g, Poria 7g, Rhizoma Atractylodis Macrocephalae 7g, Radix Angelicae Sinensis 10g, Colla Corii Asini 7g, Herba Agrimoniae 28g, Herba Cirsii 13g, Radix Paeoniae Rubra 7g, Radix Glycyrrhizae 6g, Fructus Jujubae.
CN2011101693687A 2011-06-22 2011-06-22 Traditional Chinese medicine preparation for treating paroxysmal nocturnal hemoglobinuria Expired - Fee Related CN102228563B (en)

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CN105796808A (en) * 2016-05-04 2016-07-27 包莉丽 Medicine for treating paroxysmal nocturnal hemoglobinuria

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CN1137393C (en) * 1996-07-01 2004-02-04 国际壳牌研究有限公司 Electrical logging of laminated earth formation

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CN1062144C (en) * 1995-06-08 2001-02-21 孟涛 Yisuishengxue chinese medicine preparation for tonifying marrow and promoting generation of blood

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Publication number Priority date Publication date Assignee Title
CN1137393C (en) * 1996-07-01 2004-02-04 国际壳牌研究有限公司 Electrical logging of laminated earth formation

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Title
马明.阵发性睡眠性血红蛋白尿症治疗进展.《辽宁中医杂志》.1995,(第09期), *

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Address after: 250014, room 1, building 61, No. two, No. 201 mountain road, Lixia District, Ji'nan, Shandong, China

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