CN102225111A - Traditional Chinese medicine granule for treating headache caused by rhinitis and preparation method thereof - Google Patents
Traditional Chinese medicine granule for treating headache caused by rhinitis and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine granule for treating headache caused by rhinitis and a preparation method thereof. The invention is characterized in that the formula of the traditional Chinese medicine granule comprises the following components in parts by weight: 10-20 parts of ligusticum wallichii, 20-30 parts of mentha haplocalyx, 10-20 parts of schizonepeta, 10-20 parts of notopterygium root, 10-20 parts of angelica dahurica, 10-20 parts of liquorice, 8-12 parts of radix sileris, 10-20 parts of wild ginger, 10-20 parts of cocklebur fruit, 10-20 parts of biond magnolia flower, 10-20 parts of pogostemon patchouli cinnabar, 10-20 parts of uncaria rhynchophylla and 3-5 parts of calculus bovis. The traditional Chinese medicine granule provided by the invention is an effective formulation for treating the headache caused by rhinitis, can fundamentally treat the headache caused by rhinitis, also has good treatment effects on the headache caused by other reasons and has the advantages of low treatment cost, small toxic and side effects and ideal treatment effects. The traditional Chinese medicine granule provided by the invention has obvious clinical effects through clinical application and has no obvious toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of the headache that rhinitis causes, belong to pure Chinese herbal medicine.And relate to the preparation method of this medicine.
Background technology
Nose is a key clearly, is the door of lung, and it is unimpeded that it is breathed, and the complete bad clear sun of sensitivity of olfactory sensation is supplemented nutrition.Rhinitis belongs to the traditional Chinese medical science " nasal sinusitis ", " sinusitis with purulent discharge " category.The headache feeling of fullness in the head that causes, the intelligence unconsciousness, symptom such as the tired limb of body is tired increases the weight of again after the diseases caused by exogenous pathogenic factor, easily outbreak repeatedly.The headache that is caused by rhinitis is a pertinacious disease the rhinitis headache.Medication is various in treatment at present, but bigger toxic and side effects is all arranged, and the cost height can not be satisfactory aspect therapeutic effect.
Summary of the invention
Technical problem to be solved by this invention is, a kind of Chinese medicine electuary and preparation method for the treatment of the headache that rhinitis causes is provided, and relieves the pain by wind and heat dispersing, fundamentally treats the rhinitis headache, to overcome the defective of existing such disease medicine of treatment.
It is as follows that the present invention solves the problems of the technologies described above the technical scheme that is adopted:
A kind of Chinese medicine electuary for the treatment of the headache that rhinitis causes is characterized in that its prescription is: Rhizoma Chuanxiong 10-20 part, Herba Menthae 20-30 part, Herba Schizonepetae 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Angelicae Dahuricae 10-20 part, Radix Glycyrrhizae 10-20 part, Radix Saposhnikoviae 8-12 part, Herba Asari 10-20 part, Fructus Xanthii 10-20 part, Flos Magnoliae 10-20 part, Herba Pogostemonis Cinnabaris 10-20 part, Ramulus Uncariae Cum Uncis 10-20 part, Calculus Bovis 3-5 part; Described part refers to mass parts.
Preferred prescription is: 15 parts of Rhizoma Chuanxiongs, 25 parts of Herba Menthaes, 15 parts of Herba Schizonepetae, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of the Radixs Angelicae Dahuricae, 15 parts in Radix Glycyrrhizae, 10 parts of Radix Saposhnikoviaes, 15 parts of Herba Asaris, 15 parts of Fructus Xanthii, 15 parts of Flos Magnoliaes, 15 parts of Herba Pogostemoniss, 15 parts of Ramulus Uncariae Cum Uncis, 4 parts of Calculus Boviss.
The preparation method of described Chinese medicine electuary is characterized in that:
(1), with the Rhizoma Chuanxiong of described ratio, Herba Menthae, Herba Schizonepetae, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Radix Saposhnikoviae, Herba Asari, Fructus Xanthii, Flos Magnoliae, Herba Pogostemonis, the Ramulus Uncariae Cum Uncis mix homogeneously is ground into 80 purpose granules;
(2), with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature;
(3), go on foot made mixture with (2), add the Calculus Bovis of described ratio, stir, be distributed into bag, every bag 8 gram gets final product.
The main Chinese herbal medicine of prescription of the present invention is according to traditional medicine and modern medicine analysis, and the property of medicine and pharmacological action are as follows:
Rhizoma Chuanxiong: meridian distribution of property and flavor: temperature; Hot; Return liver, gallbladder, pericardium channel.Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for menoxenia, amenorrhea dysmenorrhea, stomachache, costa sternales twinge, tumbling and swelling, headache, rheumatic arthralgia.
Herba Menthae: meridian distribution of property and flavor: cold; Hot; Return lung, Liver Channel.Function cures mainly: dispelling wind-heat, refresh oneself, rash.Be used for anemopyretic cold, epidemic febrile disease is from the beginning of, headache, conjunctival congestion, and sore throat, aphtha, rubella, measles, it is vexed that the breast side of body rises.
Herba Schizonepetae: meridian distribution of property and flavor: tepor; Hot; Return lung, Liver Channel.Function cures mainly: the diffusing wind that induces sweat, rash.Be used for the flu, the headache, measles, rubella, skin infection from the beginning of.
Rhizoma Et Radix Notopterygii: meridian distribution of property and flavor: temperature; Hot, bitter; Return bladder, kidney channel.Function cures mainly: cold expelling, dispel the wind dehumidifying, pain relieving.Be used for the anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.
The Radix Angelicae Dahuricae: meridian distribution of property and flavor: temperature; Hot; Return stomach, large intestine, lung meridian.Function cures mainly: the wind dehumidifying of loosing, understand things pain-stopping, detumescence and apocenosis.Be used for headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea.
Radix Glycyrrhizae: meridian distribution of property and flavor: flat; Sweet; GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Radix Saposhnikoviae: meridian distribution of property and flavor: tepor; Hot, sweet; Return bladder, liver, spleen channel.Function cures mainly: inducing diaphoresis to dispel wind, win and wet, relieving convulsion.Be used for headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.
Herba Asari: meridian distribution of property and flavor: temperature; Hot; Return lung, kidney, heart channel; Mild toxicity.Function cures mainly: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.Be used for anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
Fructus Xanthii: meridian distribution of property and flavor: temperature; Hot, bitter; Return lung meridian; Poisonous.Function cures mainly: the wind dehumidifying of loosing, clearing the nasal passage.Be used for headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella pruritus, arthralgia chiefly caused by damp pathogen contracture.
Flos Magnoliae: meridian distribution of property and flavor: temperature; Hot; Attach to the lung and stomach meridians.Function cures mainly: dispersing wind and cold, BITONG key.Be used for headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge.
Herba Pogostemonis: meridian distribution of property and flavor: tepor; Hot; Return spleen, stomach, lung meridian.Function cures mainly: eliminating turbid pathogen with aromatics, the appetizing preventing or arresting vomiting is delivered expelling summer-heat.Be used for turbid damp obstructing in middle-JIAO, the vomiting of gastral cavity painful abdominal mass, the heat-damp in summer asthenia, uncomfortable in chest easypro, cold-damp is closed summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.
Ramulus Uncariae Cum Uncis: meridian distribution of property and flavor: cold; Sweet; Return liver, pericardium channel.Function cures mainly: the heat clearing away suppressing the hyperactive liver, endogenous wind stopping is decided convulsion.It is dizzy to be used to have a headache, dysphoric cold, and infantile convulsion is twitched, pregnant eclamposia, hypertension.
Calculus Bovis: meridian distribution of property and flavor: cold; Sweet; Return liver, heart channel.Function cures mainly: clear away heart-fire, eliminating phlegm is had one's ideas straightened out, cool liver, endogenous wind stopping, detoxifcation.Be used for the calentura coma, middle wind-phlegm fan, infantile convulsion is twitched, and epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle.
The Fang Xieyu good effect: the traditional Chinese medical science is thought: nasal sinusitis disease due to attacking on the ailment said due to cold or exposure, and it is dizzy to have a stuffy nose, and ailment said due to cold or exposure is stayed and is not gone, and headache heals for a long time and not, when only not having, both has been wind syndrome of head.The product of diffusing ailment said due to cold or exposure end headache to loose wind so the present invention dispels.Rhizoma Chuanxiong is controlled the shaoyang channel headache in the side, and Rhizoma Et Radix Notopterygii is controlled the Taiyang channel headache, and the Radix Angelicae Dahuricae is controlled the Yangming Channel headache; Herba Asari is controlled the shaoyin channel headache, and Herba Menthae, Herba Schizonepetae, Radix Saposhnikoviae rise diffusing up, with the clear sharp head; dispelling wind pathogens, Calculus Bovis, Fructus Xanthii, Flos Magnoliae, Herba Pogostemonis, Ramulus Uncariae Cum Uncis are to strengthen the effect that dispelling wind relieves the pain in addition.Radix Glycyrrhizae and middle QI invigorating, coordinating the actions of various ingredients in a prescription makes to rise the unlikely consumption gas that looses, and all medicines share, and are total to the effect that long memorial wind relieves the pain.
Prescription of the present invention is effective prescription of treatment rhinitis headache, can fundamentally treat the rhinitis headache, and the headache that causes for other reasons also has excellent curative, and the treatment cost is low, and toxic and side effects is little, the therapeutic effect ideal.Obtained tangible clinical effectiveness through clinical practice, cure rate reaches 91.5%, and total effective rate reaches 97.9%, no obvious toxic-side effects.
The specific embodiment
Further specify the present invention below in conjunction with concrete preparation example.
Prescription example one:
The set of dispense ratio is: 10 parts of Rhizoma Chuanxiongs, 20 parts of Herba Menthaes, 10 parts of Herba Schizonepetae, 10 parts of Rhizoma Et Radix Notopterygiis, 10 parts of the Radixs Angelicae Dahuricae, 10 parts in Radix Glycyrrhizae, 8 parts of Radix Saposhnikoviaes, 10 parts of Herba Asaris, 10 parts of Fructus Xanthii, 10 parts of Flos Magnoliaes, 10 parts of Herba Pogostemoniss, 10 parts of Ramulus Uncariae Cum Uncis, 3 parts of Calculus Boviss.
Preparation method:
(1) get 10 parts of Rhizoma Chuanxiongs, 20 portions of Herba Menthaes, 10 portions of Herba Schizonepetae, 10 portions of Rhizoma Et Radix Notopterygiis, 10 parts of Radixs Angelicae Dahuricae, 10 portions of Radix Glycyrrhizaes, 8 parts of Radix Saposhnikoviaes, 10 parts of Herba Asaris, 10 portions of Fructus Xanthii, 10 parts of Flos Magnoliaes, 10 portions of Herba Pogostemoniss, 10 parts of Ramulus Uncariae Cum Uncis, 3 parts of Calculus Bovis mix homogeneously are ground into 80 purpose granules.
(2) with above-mentioned granule in 103-110 ℃ the baking 5-10 minute, be cooled to room temperature.
(3) medicamental pulverata is distributed into bag, every bag 10 gram gets final product.
Instructions about how to take medicine and usage: boiled water is taken after mixing it with water, one bag of every clothes, every day 2 times.
Prescription example two:
The set of dispense ratio is: 15 parts of Rhizoma Chuanxiongs, 25 parts of Herba Menthaes, 15 parts of Herba Schizonepetae, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of the Radixs Angelicae Dahuricae, 15 parts in Radix Glycyrrhizae, 10 parts of Radix Saposhnikoviaes, 15 parts of Herba Asaris, 15 parts of Fructus Xanthii, 15 parts of Flos Magnoliaes, 15 parts of Herba Pogostemoniss, 15 parts of Ramulus Uncariae Cum Uncis, 4 parts of Calculus Boviss.
Preparation method:
(1) get 15 parts of Rhizoma Chuanxiongs, 25 portions of Herba Menthaes, 15 portions of Herba Schizonepetae, 15 portions of Rhizoma Et Radix Notopterygiis, 15 parts of Radixs Angelicae Dahuricae, 15 portions of Radix Glycyrrhizaes, 10 parts of Radix Saposhnikoviaes, 15 parts of Herba Asaris, 15 portions of Fructus Xanthii, 15 parts of Flos Magnoliaes, 15 portions of Herba Pogostemoniss, 15 parts of Ramulus Uncariae Cum Uncis, 4 parts of Calculus Bovis mix homogeneously are ground into 80 purpose granules.
(2) with above-mentioned granule in 103-110 ℃ the baking 5-10 minute, be cooled to room temperature.
(3) medicamental pulverata is distributed into bag, every bag 10 gram gets final product.
Instructions about how to take medicine and usage are with embodiment one.
Prescription example three:
The set of dispense ratio is: 20 parts of Rhizoma Chuanxiongs, 30 parts of Herba Menthaes, 20 parts of Herba Schizonepetae, 20 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 20 parts in Radix Glycyrrhizae, 12 parts of Radix Saposhnikoviaes, 20 parts of Herba Asaris, 20 parts of Fructus Xanthii, 20 parts of Flos Magnoliaes, 20 parts of Herba Pogostemoniss, 20 parts of Ramulus Uncariae Cum Uncis, 5 parts of Calculus Boviss.
Preparation method:
(1), get 20 parts of Rhizoma Chuanxiongs, 30 portions of Herba Menthaes, 20 portions of Herba Schizonepetae, 20 portions of Rhizoma Et Radix Notopterygiis, 20 parts of Radixs Angelicae Dahuricae, 20 portions of Radix Glycyrrhizaes, 12 parts of Radix Saposhnikoviaes, 20 parts of Herba Asaris, 20 portions of Fructus Xanthii, 20 parts of Flos Magnoliaes, 20 portions of Herba Pogostemoniss, 20 parts of Ramulus Uncariae Cum Uncis, 5 parts of Calculus Bovis mix homogeneously are ground into 80 purpose granules.
(2), with above-mentioned granule in 103-110 ℃ the baking 5-10 minute, be cooled to room temperature.
(3), medicamental pulverata is distributed into bag, every bag 10 gram gets final product.
Instructions about how to take medicine and usage are with embodiment one.
It below is clinical report
From year March in February, 2009 to 2011, the inventor uses the present invention's example two treatment rhinitis headaches 75 examples of writing out a prescription in Yantai Fushan District the People's Hospital, and treats 30 examples and carry out controlled observation with using oral BIYANLING the same period, receives better effects, now is reported as follows.
1, clinical data
Physical data is observed case totally 105 examples, is divided into 2 groups at random.75 examples are organized in treatment, male 30 examples, women 45 examples; Year at age (39.5 ± 15.27); The course of disease (3 ± 1) year; Matched group 30 examples, male 20 examples, women 10 examples; Year at age (39.5 ± 15.27); The course of disease (3 ± 1) year.2 groups of physical data are learned processing by statistics, and there are no significant that meaning (P＞0.05) has comparability for difference.
2, Therapeutic Method
2.1 matched group adopts oral BIYANLING every day 2 times.2 weeks of the course of treatment.
2.2 the treatment group adopts 1 bag of the every clothes of oral medicine of the present invention, every day 2 times, 2 weeks of the course of treatment.
2.3 headache, dizzy heavy before and after the observation item treatment, the sleep situation.
2.4 statistical method adopts the SPSS statistical software to analyze.
3, criterion of therapeutical effect and therapeutic outcome
Criterion of therapeutical effect is with reference to relevant criterion of therapeutical effect in " disease of tcm judgement criterion of therapeutical effect ".Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, lab testing improve or are normal.Invalid: clinical symptoms does not have being clearly better or increases the weight of.
Therapeutic outcome
Two groups of clinical efficacies relatively see Table 1.Total effective rate treatment group is 87.9%, and matched group is 76.6%, two group and compares that difference has significance meaning (P＜0.05).With preceding relatively ※ P＜0.01 of treatment; With comparison after the treatment of control group, △ P＜0.01 this shows, medicine of the present invention is better than other medicines for treatment rhinitis headache effect, cures the effective percentage height.
Table 1 liang group clinical efficacy relatively
Group n improvement recovery from illness invalid total effective rate (%)
Treatment organizes 75 13 (17.3%) 53 (70.6%) 9 (12%) 87.9%
Matched group 30 2 (6.6%) 21 (70%) 7 (23.3%) 76.6%
Claims (3)
1. a Chinese medicine electuary for the treatment of the headache that rhinitis causes is characterized in that its prescription is: Rhizoma Chuanxiong 10-20 part, Herba Menthae 20-30 part, Herba Schizonepetae 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Angelicae Dahuricae 10-20 part, Radix Glycyrrhizae 10-20 part, Radix Saposhnikoviae 8-12 part, Herba Asari 10-20 part, Fructus Xanthii 10-20 part, Flos Magnoliae 10-20 part, Herba Pogostemonis Cinnabaris 10-20 part, Ramulus Uncariae Cum Uncis 10-20 part, Calculus Bovis 3-5 part; Described part refers to mass parts.
2. the Chinese medicine electuary of the headache that treatment rhinitis as claimed in claim 1 causes is characterized in that its prescription is: 15 parts of Rhizoma Chuanxiongs, 25 parts of Herba Menthaes; 15 parts of Herba Schizonepetae, 15 parts of Rhizoma Et Radix Notopterygiis, 115 parts of the Radixs Angelicae Dahuricae; 15 parts in Radix Glycyrrhizae; 10 parts of Radix Saposhnikoviaes, 15 parts of Herba Asaris, 15 parts of Fructus Xanthii; 15 parts of Flos Magnoliaes; 15 parts of Herba Pogostemoniss, 15 parts of Ramulus Uncariae Cum Uncis, 4 parts of Calculus Boviss.
3. the preparation method of the Chinese medicine electuary of the headache that causes as claim 1 and 2 described treatment rhinitis is characterized in that:
(1), with the Rhizoma Chuanxiong of described ratio, Herba Menthae, Herba Schizonepetae, Rhizoma Et Radix Notopterygii, the Radix Angelicae Dahuricae, Radix Glycyrrhizae, Radix Saposhnikoviae, Herba Asari, Fructus Xanthii, Flos Magnoliae, Herba Pogostemonis, the Ramulus Uncariae Cum Uncis mix homogeneously is ground into 80 purpose granules;
(2), with above-mentioned granule in 130-135 ℃ the baking 6-10 minute, be cooled to room temperature;
(3), go on foot made mixture with (2), add the Calculus Bovis of described ratio, stir packing.
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| CN201110152822A CN102225111B (en) | 2011-05-26 | 2011-05-26 | Traditional Chinese medicine granule for treating headache caused by rhinitis and preparation method thereof |
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| CN102670908A (en) * | 2012-04-13 | 2012-09-19 | 边天志 | Traditional Chinese medicine for treating rhinitis and its preparation method |
| CN107213330A (en) * | 2017-07-06 | 2017-09-29 | 合肥丰瑞隆生物科技有限公司 | Treat pharmaceutical composition, its preparation method and the preparation of acute rhinitis |
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| CN1785316A (en) * | 2005-12-06 | 2006-06-14 | 宋敏 | Medicinal tea for treating rhinopathia |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102670908A (en) * | 2012-04-13 | 2012-09-19 | 边天志 | Traditional Chinese medicine for treating rhinitis and its preparation method |
| CN102670908B (en) * | 2012-04-13 | 2014-01-08 | 边天志 | Traditional Chinese medicine for treating rhinitis and preparation method thereof |
| CN107213330A (en) * | 2017-07-06 | 2017-09-29 | 合肥丰瑞隆生物科技有限公司 | Treat pharmaceutical composition, its preparation method and the preparation of acute rhinitis |
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