CN1022167C - Light quantum treating instrument for blood - Google Patents

Abstract

The present invention relates to a medical appliance for autoblood back transfusion of human bodies through the application of the physical phenomena of ultraviolet radiation. The present invention aims to make an improvement on the basis of the prior art, a biomass detection sensor and a microcomputer automatic control system are additionally arranged, and the influence of external factors is avoided. The present invention is formed by the combination of a single chip computer, a timer, a program memory, a power failure protecting device, a data memory, a display, an operation keyboard, an alarm device, a signal converter, a driver, a motion device and a series of parallel interface circuits. The present invention has the advantages of precise structure, stable performance, self control realization, obvious curative effect on nervous system diseases which are difficult to cure, and obvious social effect and economic effect.

Description

Light quantum treating instrument for blood

The present invention is a kind of medical apparatus and instruments of using the ultraviolet radiation physical phenomenon to the human body autoblood transfusion.

The prior art of this technical field, August 9 (applying date) in 1988, to the utility model patent that Patent Office of the People's Republic of China applied for " blood therapeutic equipment ", invested patent right by No.1 Hospital Affiliated to No.4 Military Medical Univ. of PLA October 17 nineteen ninety.The patent No.: 88 2 09538.2, utility model certificate number: No. 46969, it is characterized in that constituting by object stage, billy gate, electric magnet, quartz container, raceway, light shielding device, underframe and sidewall, object stage with central opening and framework is connected as a single entity with the billy gate that has bearing, iron core bar on the crosspiece of billy gate two ends is connected with the electric magnet at underframe both ends, opens the ultraviolet radiation port that a size and billy gate stroke adapt on the underframe.This prior art just adopts the exposure dose and the moving of car frequency of Artificial Control blood, does not realize automatic control.

The objective of the invention is to be to overcome above-mentioned deficiency of the prior art, and improve on the basis of existing technology, adopt micro computer to control the replacement Artificial Control automatically, increased being radiated the detecting function of ultraviolet light intensity on the blood, avoid the influence of extraneous factor, can calculate ultraviolet radiation dosage-Biomass that blood receives.Realized with the work of Biomass apparatus for automatic control.

The present invention is combined by single-chip microcomputer, intervalometer, program storage, power-down protection apparatus, data storage, display and operation keyboard, alarm device, signal adapter, driver, telecontrol equipment and a series of parallel interface.

Advantage of the present invention and good effect are of a tightly knit structure, stable performances, in use detection system can be measured the actual Biomass that blood receives, micro computer adds up automatically, the ultraviolet radiation that receives up to blood reaches predetermined Biomass, the micro computer apparatus for automatic control quits work, and be not subjected to extraneous each factor affecting, guaranteed clinical good curative effect.Realized the adjustment of moving of car Automatic Frequency, be converted to fast frequency (60 times/minute) by slow frequency (40 times/minute).The present invention has significant curative effect to refractory nervous system disease, obviously is better than other traditional therapy, and its social benefit and economy are very remarkable, has application value widely.

Elaborate below in conjunction with accompanying drawing:

Fig. 1 represents the block diagram of micro computer automatic control circuit of the present invention.

Fig. 2 represents the circuit diagram of power-down protection apparatus.

Fig. 3 represents the circuit diagram of intervalometer, alarm device and driver.

Fig. 4 represents the circuit diagram of A/D analog-digital converter.

Fig. 5 represents the circuit diagram of display and operation keyboard.

Fig. 6 represents main program flow block diagram of the present invention.

Fig. 7 represents interrupt routine process blocks sketch map of the present invention.

Fig. 8 represents operation control panel and function key sketch map.

Among Fig. 1 by the timer 2 that operating clock is provided; be solidified with the read-only memory 3 of single-chip microcomputer 1; have power-down protection apparatus 4; and the random memory 5 of the various measurement data of buffer memory; the A/D analog-digital converter 10 that has light sensor 12 and linear amplifier 11 is combined into signal adapter; be connected with single-chip microcomputer 1 by AB, DB, CB bus respectively again, display and operating means 6, alarm device 8, light shielding device 14 and light source 15, driver 17 and telecontrol equipment 18 also are connected with single-chip microcomputer 1 with parallel interface 7,9,13,16 respectively.

Power-down protection apparatus 4 is by (Fig. 2) audion V ₁, diode V ₂, V ₃, V ₄, resistor R ₁, R ₂, R ₃, and accumulator B ₁Be combined into.B ₁, 5V line end 20,40 join with single-chip microcomputer 1 respectively.When energized, 5V voltage passes through V ₂Running voltage is provided for random memory (RAM) 5, passes through R ₃, V ₄Accumulators E ₁V is passed through in charging ₂, R ₁Read-write control line CE to RAM5 provides high level.CPU ₁Read or write that the control signal of data is by three or eight decoder 21(Fig. 4 among the RAM5), audion V ₁R ₂Produce.After the 5V power supply disconnects, accumulator E ₁Pass through V immediately ₃Provide voltage to RAM5, and pass through R ₁Read-write control line CB to RAM5 provides high level, is not lost with the various measurement data that protection is stored among the RAM5.

Timer 2 among Fig. 1 is by (the last figure of Fig. 3) quartz crystal Z ₁, resistor R _4～7, capacitor C ₂C ₃Phase inverter 18 and reset key K ₁Connection is combined into, and single-chip microcomputer (CPU) is provided ₁Operating clock.Be solidified with CPU in the read-only memory (ROM) 3 ₁Operation sequence.CPU ₁Under the effect of operating clock, read the program among the ROM3, send instruction by parallel interface 7,9,13 and 16 circuit to each several part behind the recognizer, each several part work in the timesharing control instrument.CPU ₁Can receive the order of operation keyboard input.And operate by order.CPU ₁Also read the duty and the measurement data of each several part in the instrument, and various measurement data are buffered in the random memory (RAM) 5.

Alarm device 8 is by (the middle figure of Fig. 3) resistor R _8～13, capacitor C ₄, C ₅Be combined into together with agitator 19.The audio signal that audio oscillator produced is through R ₉R ₁₀After the dividing potential drop, be transported to V ₅Base stage, again through V ₅Amplify, drive speaker B ₁Sounding alarm.In the ordinary course of things, audio oscillator is in the failure of oscillation state.When single-chip microcomputer 1 is judged operator's operate miss by the keyboard input, send the starting of oscillation signal, start audio oscillator work, oscillator signal is through V ₅Amplify, drive speaker B ₁Send alarm signal, note to remind operator.When CPU1 judges the measuring process end, also send Normal Alarm.

Driver 17 and light shielding device 14 are respectively formed three road identical circuit by (figure below of Fig. 3) and are formed.Just wherein one the tunnel be described as follows: the light emitting diode V in the circuit ₁₄, photoelectrical coupler V ₁₇In light emitting diode and resistor R ₁₇The input circuit of having formed photoelectrical coupler.Resistor R ₁₆, photoelectrical coupler V ₁₇In audion constituted the receiving loop of photosignal.Diode V ₈, line bag L ₃, audion V ₁₃Constitute output and driven the loop.The circuit of this three road same structure is driven by phase inverter 20 all, and phase inverter 20 is subjected to the control of single-chip microcomputer 1, and when single-chip microcomputer 1 sent startup command, this enabling signal was through the 5 feet input of phase inverter 20, and the output of 6 feet is sent to photoelectrical coupler V ₁₇Input circuit, V in the input circuit ₁₇Interior diode sends optical signal, photoelectrical coupler V ₁₇Receive optical signal, and convert optical signal to the signal of telecommunication, export to pliotron V ₁₃, after its signal amplified, DM adhesive, the effect of this adhesive were to open light shielding device 14, allowed ultraviolet source 15 shine on the blood by illumination window.Two-way also is controlled by CPU1 in addition, through phase inverter 20 → photoelectrical coupler V ₁₅Or V ₁₆→ driver 17, controlling magnet adhesive → release → adhesive again, the dolly that repeats this process driving placement blood repeatedly is reciprocating, makes fluctuations in blood can be subjected to the abundant irradiation of ultraviolet source 15.

Form signal adapter by A/D analog-digital converter 10, linear amplifier 11 and light sensor 12 among Fig. 1.Linear amplifier 11 parts are by (Fig. 4) resistor R ₂₂, R ₂₃And R ₂₅～27, capacitor C _7～9, light sensitive diode V ₁₈With potentiometer R ₂₄Form.V ₁₈, R ₂₇And C ₉Constituted the input circuit of amplifier.R ₂₂, R ₂₄, R ₂₅, R ₂₆, C ₇Formed amplifying circuit together with amplifier 24.R is passed through in the output of amplifier 24 ₂₃Coupling C ₈After the filtering, be transported to the input 26 of A/D converter 10, R ₂₀, C ₆, R ₂₁For A/D analog-digital converter 10 provides needed reference voltage.Three or eight decoders 21, nor gate 22 are formed the signal combination logic circuit together, and the wiring 26,27,28 of three or eight decoders is joined with CPU1 respectively.Its work process is as follows: reflect the variation of ultraviolet light source 15 by light sensor 12, this weak signal is transported to A/D analog-digital converter 10 after linear amplifier 11 amplifies.Single-chip microcomputer 1 by combinational logic circuit, sends the startup switching signal to A/D converter 10 under the control of fixed cycle operator instruction, the analog signal conversion that A/D converter 10 is sent amplifier here under the effect of switching signal becomes the discernible digital signal of computer.Single-chip microcomputer 1 reads digital signal.Through computing, draw ultraviolet intensity and biological dose.

Line end 5V, 9V, 30V respectively are connected to relevant voltage among Fig. 3,4, and line end GEN and agitator 19 join.

Among Fig. 5 by parallel interface 7(Fig. 1), phase inverter 25 and 26 non-inverting buffers 27 and 28, charactron 29～32, and resistor R _28～31And R _32～39Also have operation keyboard (Fig. 8) to form display and operating keyboard circuit.The bit code that shows charactron 29～32 is controlled through phase inverter 25 and 26 by parallel interface 7 circuit, and segment encode is controlled by non-inverting buffer 27 and 28, and display mode adopts touring scanning.Operation keyboard is made up of a reset key and 11 function keys, and operator import various command by operation keyboard.By interface 7 order is input to single-chip microcomputer 1, through behind the discriminatory analysis, the various operations of executable operations keyboard input.Various CALCULATION OF PARAMETERS in the measurement are finished in indicating instrument work.For example: light intensity, biological dose, frequency, time, number.

After this instrument energized (Fig. 6), single-chip microcomputer 1 is started working under the effect of timer 2, and by address bus AB, control bus CB, data/address bus DB read and execution of program instructions.At first each parallel interface is carried out initialization operation,, close light shielding device 14, put telecontrol equipment 18 by parallel interface 16 and be halted state by parallel interface 9 by parallel interface 7 order display default parameterss.When above-mentioned several ready after; open interruption; this instrument is in waiting state; promptly be in operation keyboard analysis and treatment state, wait for operator's operation, analysis and processing operation keyboard and program comprise: reset receptacle parameter program in metering system and the modification; start working procedure; open the program of dark slide driving vibrating device, the program of time-out/continuation, the program of Ting Jiing by force.When single-chip microcomputer 1 by after receiving the start key that operator press, just begin to start working according to setting means and parameter.Display shows the data of measuring process sign and measurement, by interface 13 open dark slide 14, light source 15 begins blood illuminator.Reciprocating by interface 16 actuation movement devices 18.

Under interrupt request singal effect (Fig. 7), regularly start 10 work of A/D analog-digital converter, single-chip microcomputer 1 is constantly gathered the data that A/D analog-digital converter 10 is sent here, to these data in addition judgment processing calculate, calculate light intensity value earlier, and constantly add up Biomass, when Biomass is communicated to 1/3 setting value by the time, accelerate vibration number, fluctuations in blood is accelerated.When measuring biological value and setting value when equating, promptly carry out halt command, preserve measurement result, close light barrier 14, stop vibration, to wait for new operational order.When pick off 12 is accepted the ultraviolet light that light source 15 sends, and convert the signal of telecommunication to, linear amplifier 11 amplifies this weak signal, flows to A/D analog-digital converter 10 then.Single-chip microcomputer 1 regularly starts 10 work of A/D analog-digital converter, handles after analog signal conversion is become digital signal again, and this process is carried out in timer interrupt routine.In interrupt routine, also to regularly change the direction adhesive → release → adhesive again of driver 17.Before not finishing a measuring process, carry out this process again and again.

Best embodiment of the present invention is that the single-chip microcomputer among Fig. 1 adopts 8031, and read only memory 3 adopts 2764, and random access memory 5 adopts 6264.

Audion V in Fig. 2 power-down protection apparatus circuit ₁Adopt 3DG6, diode V ₂, V ₃And V ₄Adopt 1N4001, resistor R ₁Adopt 10K Ω, R ₂Adopt 30K Ω, R ₃Adopt 51 Ω, all use 1/4W, accumulator E ₁Adopt 3.6V.

Resistor R in the last figure timer circuit of Fig. 3 ₄Adopt 220 Ω, R _5～7All adopt 1K Ω, all use 1/4W, capacitor C ₁ Adopt electrolysis condenser 10 μ f, 16V, C ₂Adopt thin film capacitor 0.01 μ f, 63V, C ₃Adopt ceramic disc capacitor device 11Pf, 63V, phase inverter 18 adopts 74LS04, K ₁Adopt reset key, quartz crystal Z ₁Adopt 3.9936MHZ.

Speaker B in the middle figure alarm device circuit of Fig. 3 ₁Adopt 8 Ω, 0.25W, resistor R ₈Adopt 8 Ω, R ₉Adopt 470 Ω, R ₁₀Adopt 4.7K Ω, R ₁₁Adopt 18K Ω, R ₁₂Adopt 91K Ω, all use 1/4W, capacitor C ₄Adopt thin film capacitor 0.01 μ f, C ₅Adopt monolithic capacitor 0.1 μ f, all use 63V, agitator 19 adopts NEC555.

Diode V in figure below drive circuit of Fig. 3 ₆, V ₇, V ₈Adopt 1N4002, V ₉, V ₁₀, V ₁₄Adopt light emitting diode φ 3, audion V ₁₁, V ₁₂, V ₁₃Employing reaches woods utmost point audion, photoelectrical coupler V ₁₅, V ₁₆, V ₁₇Adopt BS205, resistor R ₁₄, R ₁₅, R ₁₆Adopt 30K Ω, 1/2W, 130 Ω, 1/4W, L are adopted in R17～19 ₁, L ₂, L ₃Adopt the enamel insulated wire coiling, phase inverter 20 adopts 7406.

Three or eight decoders 21 in the A/D analog-digital converter circuit of Fig. 4 adopt 74LS138, and nor gate 22 adopts 74LS02, and A/D analog-digital converter 23 adopts ADC0809, diode V ₁₈Adopt light sensitive diode φ 3, resistor R ₂₀Adopt 1K Ω, R ₂₁Adopt 5.6K Ω, R ₂₂Adopt 30K Ω, R ₂₃Adopt 100 Ω, R ₂₅, R ₂₆, R ₂₇Adopt 470 Ω, all use 1/4W, R ₂₄Adopt 30K Ω, 1/2W, capacitor C ₇Adopt 11Pf, 63V electrolysis condenser, C ₆, C ₈Adopt 100 μ f, C ₉Adopt 10 μ f, all use the 16V electrolysis condenser, operational amplifier 24 adopts LM358.

The operation keyboard of Fig. 5 and the phase inverter in the display circuit 25,26 adopt 75452, and non-inverting buffer 27,28 adopts 7407, and charactron 29～32 adopts BS205, resistor R ₂₈～31 adopt 30K Ω, R _32～39Adopt 130 Ω, all use 1/4W.

Parallel interface 7,9,13,16 among Fig. 1 also all adopts 8155.

The operation control panel of Fig. 8 adopts insulation board, loads onto lathe power knob 33 and 35, four charactrons 36 of 34, three light emitting diodes and a reset key and 11 function button 37 electric elements.

When operation, press the logical button 33(Fig. 8 of power supply) power connection, this moment, exhaust fan rotated, and quartz burner is bright, and charactron 36 sign bits show " 6 " and flash that digit order number shows " 120 ", and it is normal that the expression instrument starts the back, is in set condition.

This instrument is provided with 4 digital display tubes 36, the setting of indicating instrument and running statuses all the time.One of Far Left is a sign bit, represents when flash this position that instrument is in set condition, does not flash then expression and is in measurement or measures end.

The convertible Instrument working state of setting/measurement key.When this key was in set condition, the charactron highest order was flashed, and can carry out the setting of instrument parameter, the value bit display setting position of charactron this moment.When being in the measurement state, the charactron highest order is not flashed, and value bit shows measuring process or measures and finish.

After the various parameter settings of instrument finish, press start key, can start working.

In the instrument running, in the time of need suspending because of certain reason, press time-out/continuation key, the instrument operation suspension.

Under any circumstance press stop key, instrument promptly finishes when time measurement and out of service.

Biomass, frequency and time key are set/are measured the control of key and cooperated with "+", "-" key, can finish the setting and the demonstration task of instrument parameter.

When starting operation, press the light intensity key, then show ultraviolet irradiation intensity at that time.

Press the reset key instrument and recover inner initial setting up parameter, promptly Biomass is 12, and frequency is 50 times/minute, and irradiation time is 8 minutes.

Total number of persons/total time key is inoperative under set condition, under the measurement state, presses this key repeatedly, and treatment total number of persons and instrument used total time since charactron was rotated display instrument and used.

Under set condition, press+/ time key or-/the number key, cooperate with the Biomass key, finish the setting and the modification of instrument parameter.Under the measurement state, press these two keys and can show time and the number of after time start, using respectively.

When this instrument uses end to need to shut down, press the disconnected button 34 of power supply.

Claims (5)

1; light quantum treating instrument for blood has object stage; billy gate; electric magnet; quartz container; raceway; light shielding device; underframe and sidewall constitute; object stage with central opening and framework is connected as a single entity with the billy gate that has bearing; iron core bar on the crosspiece of billy gate two ends is connected with the electric magnet at underframe both ends; open the ultraviolet radiation port that a size and billy gate stroke adapt on the underframe; also has singlechip CPU; memory RAM and ROM; A/D Analog to Digital Converter and parallel interface; feature of the present invention is by the intervalometer that operating clock is provided [2]; be solidified with the read-only memory [3] of single-chip microcomputer [1]; have power-down protection apparatus [4]; and the random memory of the various measurement data of buffer memory [5]; the A/D analog-digital converter [10] that has light sensor [12] and linear amplifier [11] is combined into signal adapter; pass through AB again respectively; DB; the CB bus is connected with single-chip microcomputer [1], display and operating means [6]; alarm device [8]; light shielding device [14] and light source [15]; driver [17] and telecontrol equipment [18] are also used parallel interface [7] respectively; [9]; [13]; [16] be connected with single-chip microcomputer [1] and combine.

2,, it is characterized in that by audion V according to the circuit of the described therapeutic instrument of claim 1 ₁, diode V ₂, V ₃, V ₄, resistor R ₁, R ₂, R ₃With accumulator E ₁, E ₁, the line end [20] of 5V, [40] join V with single-chip microcomputer [1] respectively ₂, R ₁Control line CE with random memory [5] is connected again, and these elements connect the circuit that is combined into power-down protection apparatus [4].

3, according to the circuit of claim 1 or 2 described therapeutic instruments, it is characterized in that by quartz crystal Z ₁, resistor R _4～7, capacitor C ₂, C ₃, phase inverter [18] and reset key K ₁Connect the circuit that is combined into intervalometer [2], by resistor R _8～12, capacitor C ₄, C ₅And agitator [19] is combined into audio oscillator together, this again with R ₉, R ₁₀, V ₅With speaker B ₁Be combined into alarm device, by light emitting diode V ₉, V ₁₀, V ₁₄, photoelectrical coupler V _15～17In light emitting diode and resistor R _17～19Be combined into the input circuit of No. three photoelectrical couplers, resistor R _14～18, photoelectrical coupler V _15～17In audion constitute the receiving loop of three road photosignals, diode V _6～8, line bag L _1～3, audion V _11～13Be combined into three tunnel outputs and drive the loop, respectively form three tunnel identical circuit with this, being connected with single-chip microcomputer [1] with phase inverter [20] is combined into the circuit of identical driver [17] and light shielding device [14] again.

4, according to claim 1 or 3 circuit of a described therapeutic instrument wherein, it is characterized in that by resistor R ₂₂, R ₂₃And R _25～27, capacitor C _7～9, light sensitive diode V ₁₈With potentiometer R ₂₄Connection is combined into linear amplifier [11], by V ₁₈, R ₂₇, C ₉Constitute the amplifier input circuit, by R ₂₂, R ₂₄～R ₂₆, C ₇And amplifier [24] is combined into amplifying circuit together, by R ₂₀, C ₆, R ₂₁Be combined into the circuit of reference voltage, be combined into signal logic circuit together by three or eight decoders [21] and nor gate [22], its wiring [26], [27], [28] are connected with single-chip microcomputer [1] respectively.

5, according to claim 1 or 4 circuit of a described therapeutic instrument wherein, it is characterized in that by phase inverter [25] and [26], non-inverting buffer [27] and [28], charactron [29～32] and resistor R _28～31And R _32～39, also have button [33,34], light emitting diode [35], charactron [36] and button [37] on the operation control panel to connect the circuit that is combined into display and operation keyboard.

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