CN102178904A - Medicament for treating secondary azoospermia and preparation process thereof - Google Patents
Medicament for treating secondary azoospermia and preparation process thereof Download PDFInfo
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- CN102178904A CN102178904A CN2011101208431A CN201110120843A CN102178904A CN 102178904 A CN102178904 A CN 102178904A CN 2011101208431 A CN2011101208431 A CN 2011101208431A CN 201110120843 A CN201110120843 A CN 201110120843A CN 102178904 A CN102178904 A CN 102178904A
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Abstract
The invention relates to a medicament for treating secondary azoospermia and a preparation process thereof. The medicament comprises the following main raw materials: white peony root, prepared fleece-flower root, broomrape, raspberry, cuttlefish bone, turmeric root-tuber and the like. The preparation process comprises the following steps: decocting the raw materials based on a strict weight ratio to obtain juice; drying; and finally filling the dried materials into hard capsules to obtain the medicament. The medicament has the advantages of obvious treatment effect on secondary azoospermia and no side effects.
Description
The present invention relates to a kind of medicine of the male's of treatment Secondary cases azoospermia, is the Chinese patent medicine of feedstock production with the Chinese crude drug specifically, the invention still further relates to the preparation technology of this medicine.
In male infertility, azoospermia can be divided into two kinds of congenital azoospermia and Secondary cases azoospermias, its cause of disease complexity, and doctor trained in Western medicine adopts treatments such as testosterone, HCG and clomiphene more at present, but effect is difficult to certainly, and side effect is arranged.
The inventor thinks that according to year clinical experience surplus 40 male's Secondary cases azoospermia mostly is weak, adds due to the psychological impact, and Chinese medical discrimination belongs to deficiency of the kidney.The present invention is a kind of compound Chinese medicinal preparation and preparation technology thereof, and its primary raw material is made up of the Radix Paeoniae Alba, Radix Polygoni Multiflori Preparata, Herba Cistanches, Fructus Rubi, extra large Piao sheath, Radix Curcumae.Each component is by weight ratio: the Radix Paeoniae Alba 20%, Radix Polygoni Multiflori Preparata 20%, Herba Cistanches 15%, 15% part of Fructus Rubi, extra large Piao sheath 15%, Radix Curcumae 15%.Its preparation technology is: 1, insert above-mentioned Six-element Chinese medicine in the medicine pot earlier, 12 times of water yields that add Six-element medicine gross weight decoct, and to boiling back 60 minutes, it is standby to take concoction from fire; 2,12 times of water yields that add former Six-element medicine gross weight on medicinal residues are carried out the 2nd decoction, and to boiling back 60 minutes Zhongli's fire, it is standby to take concoction; 3,12 times of water yields that add former Six-element medicine gross weight on medicinal residues are carried out the 3rd decoction, and to boiling back 60 minutes Zhongli's fire, it is standby to take concoction; 4, with the medicine juice that decocts for 3 times through mix, filter, remove slag, drying, insert hard capsule and form.
Press Chinese traditional medicine principle, the Radix Paeoniae Alba enrich blood YIN nourishing, vital essence replenishing and marrow benifiting, the Radix Polygoni Multiflori Preparata the kidney invigorating and essence nourishing, Herba Cistanches kidney invigorating and YANG supporting, Fructus Rubi reinforcing the kindey to control nocturnal emission, Endoconcha Sepiae convergence controlling nocturnal emission with astringent drugs, the Radix Curcumae heart fire-clearing upset-relieving, the effect that the compound Chinese medicinal preparation of making has strong kidney-tonifying sperm-generating that makes up, essence and blood must be mended, melancholy must separating, thus reach the purpose of recovering spermatogenesis, treatment Secondary cases azoospermia.
I am diagnosis and treatment necrospermia patient 20 examples for many years.The standard of including in is not seen sperm for continuous 3 the seminal fluid centrifugation microscopic examination of patient, gets rid of varicocele, gets rid of urinary system, reproductive tract acute inflammation, gets rid of Treatment of azoospermia.Be divided into treatment at random and organize 10 examples, matched group 10 examples.Two groups of patient ages, the course of disease etc. are learned by statistics and are handled there was no significant difference.Treatment group patient every day oral invention side finished product 20 gram, with 30 days be a course of treatment, 3 courses of treatment of logotype.Matched group is taken the clomifene citrate capsule, and every day 1 time, each 25 milligrams, serveing on 25 days was 1 course of treatment; After the drug withdrawal 5 days, repeat to take, totally 3 courses of treatment.The colored sperm quality detection system of the WLJY-9000 type that semen analysis adopts Weili Technology and Trade Co., Beijing to provide.Cure: the semen efamination motility of sperm is normal, and sperm count is greater than 20 * 109/L.Effectively: the visible sperm of semen efamination, but sperm concentration or motility rate are undesired.Invalid: assay does not still have sperm.The treatment group is cured 4 examples, effective 3 examples, invalid 3 examples, total effective rate 70.0%; Matched group is cured 0 example, effective 1 example, total effective rate 10.0%.Treatment group curative effect obviously is better than matched group, and difference has the significance meaning.
The present invention has following advantage: one, curative effect is reliable, and two, have no side effect, three, taking convenience, four, method for making is simple, and suitable society and economic benefit are arranged.
Below in conjunction with embodiment the present invention is described in further detail.
Embodiment
By weight the Radix Paeoniae Alba 200 grams, Radix Polygoni Multiflori Preparata 200 grams, Herba Cistanches 150 grams, Fructus Rubi 150 grams, extra large Piao sheath 150 grams, Radix Curcumae 150 grams.Above-mentioned Six-element medicine is inserted and is added water 12000 gram decoctions in the medicine pot to boiling back 60 minutes, and it is standby to take concoction from fire.Add for the second time the row decoction again of water 12000 grams on the Six-element medicinal residues, to boiling back 60 minutes, it is standby to take concoction from fire.Fried in shallow oil 12 times of water yields that add former Six-element medicine gross weight on twice the medicinal residues more and carried out the 3rd time and decoct, to boiling back 60 minutes Zhongli's fire, it is standby to take concoction.Three medicine juice are mixed, and after filtration, drying is inserted hard capsule and is formed.
Claims (3)
1. a medicine for the treatment of the Secondary cases azoospermia is characterized in that its primary raw material is made up of following component by weight ratio: the Radix Paeoniae Alba 20%, Radix Polygoni Multiflori Preparata 20%, Herba Cistanches 15%, 15% part of Fructus Rubi, extra large Piao sheath 15%, Radix Curcumae 15%.
2. the medicine of the described treatment Secondary cases of claim 1 azoospermia is characterized in that it is a capsule.
3. the preparation technology of the pharmaceutical preparation described in the claim 1, it is characterized in that this technology is made up of the following step: 1, insert above-mentioned Six-element Chinese medicine in the medicine pot earlier, 12 times of water yields that add Six-element medicine gross weight decoct, and to boiling back 60 minutes, it is standby to take concoction from fire; 2,12 times of water yields that add former Six-element medicine gross weight on medicinal residues are carried out the 2nd decoction, and to boiling back 60 minutes Zhongli's fire, it is standby to take concoction; 3,12 times of water yields that add former Six-element medicine gross weight on medicinal residues are carried out the 3rd decoction, and to boiling back 60 minutes Zhongli's fire, it is standby to take concoction; 4, with the medicine juice that decocts for 3 times through mix, filter, remove slag, drying, insert hard capsule and form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011101208431A CN102178904B (en) | 2011-05-11 | 2011-05-11 | Medicament for treating secondary azoospermia and preparation process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011101208431A CN102178904B (en) | 2011-05-11 | 2011-05-11 | Medicament for treating secondary azoospermia and preparation process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102178904A true CN102178904A (en) | 2011-09-14 |
| CN102178904B CN102178904B (en) | 2012-06-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2011101208431A Expired - Fee Related CN102178904B (en) | 2011-05-11 | 2011-05-11 | Medicament for treating secondary azoospermia and preparation process thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435453A (en) * | 2014-10-09 | 2015-03-25 | 胡兰春 | Medicine for treating gynecologic inflammation and preparation method of medicine |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015621A (en) * | 2006-12-31 | 2007-08-15 | 徐究竟 | Medicine for treating necrospermia and its preparation process |
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2011
- 2011-05-11 CN CN2011101208431A patent/CN102178904B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015621A (en) * | 2006-12-31 | 2007-08-15 | 徐究竟 | Medicine for treating necrospermia and its preparation process |
Non-Patent Citations (1)
| Title |
|---|
| 《中国当代医药》 20090310 徐波等 弱精子症的中医证治研究 58-61 1-3 第16卷, 第05期 2 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435453A (en) * | 2014-10-09 | 2015-03-25 | 胡兰春 | Medicine for treating gynecologic inflammation and preparation method of medicine |
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| Publication number | Publication date |
|---|---|
| CN102178904B (en) | 2012-06-13 |
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Granted publication date: 20120613 Termination date: 20140511 |