CN102164675A - 用于数字微流体的预装试剂贮库的可替换载体 - Google Patents
用于数字微流体的预装试剂贮库的可替换载体 Download PDFInfo
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- CN102164675A CN102164675A CN200980139397XA CN200980139397A CN102164675A CN 102164675 A CN102164675 A CN 102164675A CN 200980139397X A CN200980139397X A CN 200980139397XA CN 200980139397 A CN200980139397 A CN 200980139397A CN 102164675 A CN102164675 A CN 102164675A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0427—Electrowetting
Abstract
Description
Claims (34)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US12/285,326 US8187864B2 (en) | 2008-10-01 | 2008-10-01 | Exchangeable sheets pre-loaded with reagent depots for digital microfluidics |
US12/285,326 | 2008-10-01 | ||
PCT/EP2009/062657 WO2010037763A1 (en) | 2008-10-01 | 2009-09-30 | Exchangeable carriers pre-loaded with reagent depots for digital microfluidics |
Publications (2)
Publication Number | Publication Date |
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CN102164675A true CN102164675A (zh) | 2011-08-24 |
CN102164675B CN102164675B (zh) | 2014-11-12 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200980139397.XA Active CN102164675B (zh) | 2008-10-01 | 2009-09-30 | 用于数字微流体的预装试剂贮库的可替换载体 |
Country Status (7)
Country | Link |
---|---|
US (2) | US8187864B2 (zh) |
EP (1) | EP2334434B1 (zh) |
CN (1) | CN102164675B (zh) |
AU (1) | AU2009299892B2 (zh) |
CA (1) | CA2739000C (zh) |
HK (1) | HK1158134A1 (zh) |
WO (1) | WO2010037763A1 (zh) |
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CN104321141A (zh) * | 2013-05-23 | 2015-01-28 | 泰肯贸易股份公司 | 具有可调换的pcb的数字微流体系统 |
CN107803228A (zh) * | 2017-11-06 | 2018-03-16 | 南京理工大学 | 一种自动分离水油混合液滴的装置及其分离方法 |
CN108474782A (zh) * | 2015-09-29 | 2018-08-31 | 英国质谱公司 | 电容耦合reims技术和光学透明对电极 |
CN108700601A (zh) * | 2015-11-25 | 2018-10-23 | 斯佩克特拉迪尼有限责任公司 | 用于微流体盒的系统和装置 |
CN109603928A (zh) * | 2018-09-06 | 2019-04-12 | 澳门大学 | 基于液滴微流体控制的液滴分割装置及方法 |
CN109647549A (zh) * | 2018-12-17 | 2019-04-19 | 南方科技大学 | 一种易替换的疏水介电薄膜和一种微流控芯片 |
CN109894168A (zh) * | 2019-03-25 | 2019-06-18 | 京东方科技集团股份有限公司 | 微流控基板及微全分析系统 |
CN110506200A (zh) * | 2017-03-31 | 2019-11-26 | 多伦多大学管理委员会 | 用于在数字微流控装置中过滤小体积非均相悬浮液的方法 |
CN110665556A (zh) * | 2019-09-30 | 2020-01-10 | 浙江大学 | 基于疏水薄膜可复用单层数字微流控芯片及快速制备方法 |
CN110665554A (zh) * | 2019-09-30 | 2020-01-10 | 浙江大学 | 基于聚合物复合薄膜快速制备双层dmf芯片及制备方法 |
CN110882729A (zh) * | 2019-09-30 | 2020-03-17 | 浙江大学 | 基于聚合物复合膜快速制备单层dmf芯片及制备方法 |
US10777398B2 (en) | 2015-03-06 | 2020-09-15 | Micromass Uk Limited | Spectrometric analysis |
US10777397B2 (en) | 2015-03-06 | 2020-09-15 | Micromass Uk Limited | Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry (“REIMS”) device |
US10916415B2 (en) | 2015-03-06 | 2021-02-09 | Micromass Uk Limited | Liquid trap or separator for electrosurgical applications |
US10978284B2 (en) | 2015-03-06 | 2021-04-13 | Micromass Uk Limited | Imaging guided ambient ionisation mass spectrometry |
US11031222B2 (en) | 2015-03-06 | 2021-06-08 | Micromass Uk Limited | Chemically guided ambient ionisation mass spectrometry |
US11037774B2 (en) | 2015-03-06 | 2021-06-15 | Micromass Uk Limited | Physically guided rapid evaporative ionisation mass spectrometry (“REIMS”) |
US11139156B2 (en) | 2015-03-06 | 2021-10-05 | Micromass Uk Limited | In vivo endoscopic tissue identification tool |
CN113842963A (zh) * | 2021-10-29 | 2021-12-28 | 佛山奥素博新科技有限公司 | 一种微液滴生成系统及生成方法 |
US11239066B2 (en) | 2015-03-06 | 2022-02-01 | Micromass Uk Limited | Cell population analysis |
CN113996358A (zh) * | 2021-11-02 | 2022-02-01 | 哈尔滨工业大学 | 一种基于阳极氧化法的超疏水数字微流控芯片、制造方法和液滴控制系统 |
US11264223B2 (en) | 2015-03-06 | 2022-03-01 | Micromass Uk Limited | Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples |
US11270876B2 (en) | 2015-03-06 | 2022-03-08 | Micromass Uk Limited | Ionisation of gaseous samples |
US11282688B2 (en) | 2015-03-06 | 2022-03-22 | Micromass Uk Limited | Spectrometric analysis of microbes |
US11289320B2 (en) | 2015-03-06 | 2022-03-29 | Micromass Uk Limited | Tissue analysis by mass spectrometry or ion mobility spectrometry |
US11342170B2 (en) | 2015-03-06 | 2022-05-24 | Micromass Uk Limited | Collision surface for improved ionisation |
US11367605B2 (en) | 2015-03-06 | 2022-06-21 | Micromass Uk Limited | Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue |
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US8187864B2 (en) | 2008-10-01 | 2012-05-29 | The Governing Council Of The University Of Toronto | Exchangeable sheets pre-loaded with reagent depots for digital microfluidics |
US8053239B2 (en) | 2008-10-08 | 2011-11-08 | The Governing Council Of The University Of Toronto | Digital microfluidic method for protein extraction by precipitation from heterogeneous mixtures |
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DE102010061182B4 (de) * | 2010-12-13 | 2013-02-07 | Presens Precision Sensing Gmbh | Sensoranordnung, Verfahren und Messsystem zur Erfassung der Verteilung wenigstens einer Veränderlichen eines Objekts |
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US8821705B2 (en) * | 2011-11-25 | 2014-09-02 | Tecan Trading Ag | Digital microfluidics system with disposable cartridges |
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2008
- 2008-10-01 US US12/285,326 patent/US8187864B2/en active Active
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2009
- 2009-09-30 US US13/122,311 patent/US8993348B2/en active Active
- 2009-09-30 CN CN200980139397.XA patent/CN102164675B/zh active Active
- 2009-09-30 CA CA2739000A patent/CA2739000C/en active Active
- 2009-09-30 WO PCT/EP2009/062657 patent/WO2010037763A1/en active Application Filing
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Also Published As
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HK1158134A1 (zh) | 2012-07-13 |
EP2334434A1 (en) | 2011-06-22 |
CA2739000C (en) | 2017-06-06 |
AU2009299892B2 (en) | 2015-01-29 |
US8187864B2 (en) | 2012-05-29 |
US20110240471A1 (en) | 2011-10-06 |
EP2334434B1 (en) | 2020-04-08 |
US8993348B2 (en) | 2015-03-31 |
AU2009299892A1 (en) | 2010-04-08 |
CN102164675B (zh) | 2014-11-12 |
CA2739000A1 (en) | 2010-04-08 |
WO2010037763A1 (en) | 2010-04-08 |
US20100081578A1 (en) | 2010-04-01 |
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