CN102155906A - Multipoint linked device and method for measuring thickness of bio-prosthetic valve - Google Patents
Multipoint linked device and method for measuring thickness of bio-prosthetic valve Download PDFInfo
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- CN102155906A CN102155906A CN 201110078317 CN201110078317A CN102155906A CN 102155906 A CN102155906 A CN 102155906A CN 201110078317 CN201110078317 CN 201110078317 CN 201110078317 A CN201110078317 A CN 201110078317A CN 102155906 A CN102155906 A CN 102155906A
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- prosthetic valve
- artificial bio
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Abstract
The invention provides a multipoint linked device and a method for measuring thickness of a bio-prosthetic valve. The device for measuring thickness of the bio-prosthetic valve, provided by the invention, comprises: a rack, a vertical power transmitter, a micro pressure sensor bar, an air storage tank, an air valve, an gas transmission pipeline, a gas/liquid separator, a vacuum transmitting pipeline, an XY-type power transmitting platform, a motor, a pressure induction machine set and a vacuum pump, wherein a plurality of sensing elements in the micro pressure sensor bar measure the thicknesses of bio-prosthetic valves placed on the XY-type power transmitting platform in a multipoint linkage manner.
Description
Technical field
The present invention relates to a kind of medicine equipment measuring equipment, particularly relate to a kind of apparatus and method of measuring artificial bio-prosthetic valve thickness.
Background technology
In the preparation process of artificial bio-prosthetic valve, the thickness effect of pericardium material also has influence on the assembling of mediatory type artificial bio-prosthetic valve and carries effect to tension load, tensile strength, the length growth rate of artificial bio-prosthetic valve.From prolonged application, the endurance quality instability that causes owing to artificial bio-prosthetic valve uneven thickness one property also is the key point place.
Adopt manual mode of operation to measure for artificial bio-prosthetic valve thickness at present more.
For example, at Eduardo Jorge-Herrero, Carlos Fonseca, Alexandra P.Barge, Javier Turnay, Nieves Olmo, Pilar Fern á ndez, Mar í a A.Lizarbe, document Biocompatibility and calcification of bovine pericardium employed for the construction of cardiac bioprostheses treated with different chemical crosslink methods (the Artificial Organs.2010 of Jos é M.Garc í a P á ez, 34 (5): E168-E176), adopt the thickness of 5 different loci of digital micrometer measurement pericardium material of Mitutoyo company, average computation draws the general thickness valuation of pericardium material then.
At Joshua J.Lovekamp, Dan T.Simionescu, Jeremy J.Mercuri, Brett Zubiate, Michael S.Sacks, the document Stability and function of glycosaminoglycans in porcine bioprosthetic heart valves (Biomaterials.2006 of Narendra R.Vyavahare, 27:1507-1518), adopt the thickness of 5 different loci of pointer micrometer measurement pericardium material of Ozaki company, average computation draws the general thickness valuation of pericardium material then.
The artificial bio-prosthetic valve measurer for thickness that adopts in the above-mentioned document can only be operated by single-point, and data acquisition face is very little.Problems such as therefore, the metering system for artificial bio-prosthetic valve thickness exists survey area little at present, and the extraneous hold-up time of data poor repeatability and pericardium material is long.
In addition, the thickness measure for artificial bio-prosthetic valve in the above-mentioned prior art is bit by bit to get point measurement by manual, and systematic error is bigger.The artificial bio-prosthetic valve uneven thickness one that this is easy to cause in the follow-up cutting process makes that the permanance of artificial bio-prosthetic valve is relatively poor, occurs the state of local fracture in permanent use.
Summary of the invention
The object of the present invention is to provide a kind of multiple spot and dynamic formula to measure the device and method of artificial bio-prosthetic valve thickness, to overcome the above-mentioned defective that prior art exists.
According to an aspect of the present invention, a kind of artificial bio-prosthetic valve measurer for thickness is provided, and it comprises: frame, vertical power transmission device, micro pressure inductive rod, gas-holder, air valve, gas transmission pipeline, gas-liquid separator, vacuum conveyer tube road, XY type power transmission platform, motor, pressure sensitive unit and vacuum pump.Wherein said vertical power transmission device is fixed on the described frame; Described micro pressure inductive rod is fixed to described vertical power transmission device, and links to each other with described pressure sensitive unit; Described gas transmission pipeline links to each other the central tube of described gas-holder with described micro pressure inductive rod, so that purge gas is supplied to described micro pressure inductive rod, and is provided with described air valve and described gas-liquid separator along described gas transmission pipeline; Described XY type power transmission platform is connected to described motor, by described motor-driven; Described vacuum conveyer tube road links to each other described XY type power transmission platform with described vacuum pump, so as during to measure to vacuumizing between described XY type power transmission platform and the artificial bio-prosthetic valve that is placed on it.Wherein, by a plurality of sensing elements in the described micro pressure inductive rod thickness that is placed on the artificial bio-prosthetic valve on the described XY type power transmission platform is carried out multiple spot and dynamic formula measurement.
According to a further aspect in the invention, provide a kind of artificial bio-prosthetic valve method for measuring thickness, it may further comprise the steps: artificial bio-prosthetic valve is placed on the XY type power transmission platform; Utilize gas that artificial bio-prosthetic valve is purged; To vacuumizing between artificial bio-prosthetic valve and the XY type power transmission platform, so that artificial bio-prosthetic valve is fixed and is attached on the XY type power transmission platform; Make the micro pressure inductive rod contact artificial bio-prosthetic valve on the described XY type power transmission platform, the thickness of described artificial bio-prosthetic valve is carried out multiple spot and dynamic formula is measured by a plurality of sensing elements in the micro pressure inductive rod; Measurement result is averaged, thereby obtain the average thickness of the artificial bio-prosthetic valve in measured zone.
Artificial bio-prosthetic valve method for measuring thickness of the present invention also can comprise step: move described XY type power transmission platform, with the thickness of the artificial bio-prosthetic valve of measuring zones of different.
In artificial bio-prosthetic valve measurer for thickness of the present invention and method, preferably, the induction end plane of the sensing element of described micro pressure inductive rod is circular, and has the diameter of 1mm-100mm.More preferably, the diameter on the induction end plane of the sensing element of described micro pressure inductive rod is 1mm-20mm.
Preferably, the density that is provided with of sensing element is 5-20/cm in the described micro pressure inductive rod
2
Preferably, at least a in described gas-holder stored nitrogen and the carbon dioxide.
Preferably, described purge step continues the time of 10-200s.
According to artificial bio-prosthetic valve measurer for thickness of the present invention and method, in the preparation process of artificial bio-prosthetic valve, adopt multiple spot and dynamic formula measuring technique that its thickness is measured, can measure the thickness of pericardium material quickly and accurately, thereby for follow-up cutting technology provides good work target spot, therefore can the good and stable artificial bio-prosthetic valve of processability.
Multiple spot of the present invention and dynamic formula measuring technique, can be disposable treat cutting zone multidraw at the pericardium material, and moving the measurement, thereby avoided the error in the single-point repetition formula measuring process, also shorten simultaneously the extraneous hold-up time of pericardium material, accelerated the progress of continous way manufacture craft flow process.
Description of drawings
Fig. 1 is that multiple spot and dynamic formula are measured the structural representation of the device of artificial bio-prosthetic valve thickness according to the preferred embodiment of the invention.
Embodiment
Below in conjunction with the preferred embodiment shown in the accompanying drawing artificial bio-prosthetic valve measurer for thickness of the present invention and method are elaborated.
As shown in Figure 1, the artificial bio-prosthetic valve measurer for thickness comprises according to the preferred embodiment of the invention: frame 1, vertical power transmission device 2, micro pressure inductive rod 3, gas-holder 4, air valve 5, gas transmission pipeline 6, gas-liquid separator 7, vacuum conveyer tube road 8, XY type power transmission platform 9, motor 10, pressure sensitive unit 11 and vacuum pump 12.
Vertical power transmission device 2 is fixed on the frame 1.Vertical power transmission device 2 can adopt mechanical type transmitter, fluid pressure type transmitter or pneumatic type transmitter, and it plays regulation and control micro pressure inductive rod 3 in operation.
Micro pressure inductive rod 3 is fixed to vertical power transmission device 2.Its controlling at vertical power transmission device 2 is moved down, and the end of sensing element contacts with artificial bio-prosthetic valve on being placed on XY type power transmission platform 9, with the thickness of measurement artificial bio-prosthetic valve.The product that micro pressure inductive rod 3 can adopt commerce to purchase.As shown in Figure 1, it has cylindrical base and a plurality of sensing elements that are installed in the described base portion usually, and described cylindrical base has central tube.
The induction end plane of sensing element is preferably circular flat in the micro pressure inductive rod 3, and its diameter is adjustable, and diameter range is 0.1-1000mm, is preferably 1-100mm, more preferably 1-20mm.The quantity of sensing element or density can be provided with as required, in one embodiment of the invention, and every cm
2The zone in be provided with 5-20 sensing element.
Pressure sensitive unit 11 links to each other with micro pressure inductive rod 3, calculates and handles with the information such as pressure that micro pressure inductive rod 3 is responded to, thereby obtain measurement data.The product that pressure sensitive unit 11 can adopt commerce to purchase is for example available from Taiwan gold vessel MINDMAN, Japanese PISCO, NISCON, SMC, CONVUM, the product of U.S. HUMPHREY.
One end of gas transmission pipeline 6 is connected to gas-holder 4, and is provided with air valve 5 at gas transmission pipeline 6, is used for controlling the conveying of gas-holder 4 gases.Gas in the gas-holder 4 is used for artificial bio-prosthetic valve is purged, to purge the impurity such as liquid component on artificial bio-prosthetic valve surface.Preferably, purge time is 10-200s.Preferably, the one or both in use nitrogen and the carbon dioxide is as purge gas.But the invention is not restricted to this, but can use any suitable inert gas.In addition, in Fig. 1, only show a gas-holder and an air valve; But as required, can there be two or more gas-holder and air valve, to be used for the storage and the conveying of gas with various (for example nitrogen, carbon dioxide etc.).
Gas-liquid separator 7 links to each other with gas transmission pipeline 6.This is because the gas in the gas-holder can contain steam usually.Gas-liquid separator 7 is used to absorb described steam.Gas transmission pipeline 6 links to each other at the central tube of the other end with micro pressure inductive rod 3, purge gas is supplied to micro pressure inductive rod 3 through behind the gas-liquid separator 7.This connection can realize at an easy rate by suitable connecting tube (for example proofed sleeve).
Vacuum conveyer tube road 8 one ends are connected to vacuum pump 12, and the other end is connected to XY type power transmission platform 9.By 12 pairs of XY types of vacuum pump power transmission platform 9 be placed between the artificial bio-prosthetic valve on this platform and vacuumize, so that artificial bio-prosthetic valve is attached on the platform.Preferably, vacuum tightness is 0-6000Pa.
XY type power transmission platform 9 is connected to motor 10, is driven by motor 10 and realizes moving of this platform.
Operating process according to multiple spot of the present invention and dynamic formula artificial bio-prosthetic valve measurer for thickness is as follows.
Earlier artificial bio-prosthetic valve is placed on the XY type power transmission platform 9, opens 5 pairs of artificial bio-prosthetic valves of air valve then and carry out gas purging.Afterwards, start 12 pairs of artificial bio-prosthetic valves of vacuum pump and XY type power transmission platform 9 vacuumizes, make artificial bio-prosthetic valve fix and be attached on the XY type power transmission platform 9.Make it to contact by vertical power transmission device 2 operation micro pressure inductive rod 3 with artificial bio-prosthetic valve.When the pressure between micro pressure inductive rod 3 and the artificial bio-prosthetic valve reaches certain value, the thickness of artificial bio-prosthetic valve is carried out multiple spot and dynamic formula is measured by a plurality of sensing elements in the micro pressure inductive rod 3, that is, calculate the thickness of a plurality of points of artificial bio-prosthetic valve simultaneously.Calculate the average thickness of the artificial bio-prosthetic valve in measured zone then by pressure sensitive unit 11.
According to one embodiment of present invention, in above-mentioned measuring process, when micro pressure inductive rod 3 contact artificial bio-prosthetic valves reach certain pressure, can calculate the thickness of its contact site by the displacement with respect to reference point or starting point of each sensing element in the micro pressure inductive rod 3.For example, in a preferred embodiment, can be with the initial fixation point parallel as reference point or the starting point of measuring sensing element displacement with the top of gas transmission pipeline 6.
By multiple spot of the present invention and dynamic formula artificial bio-prosthetic valve measurer for thickness and method, can measure simultaneously the thickness at a plurality of positions in the artificial bio-prosthetic valve certain limit.And by regulating the circular flat size of sensing element end, the scope of its measuring point can be regulated; By moving of XY type power transmission platform, its measured zone can be regulated.
Reference numerals list:
1: frame, 2: Vertical Dynamic transmitter, 3: micro pressure inductive rod, 4: air accumulator, 5: air valve, 6: gas transmission pipeline, 7: gas-liquid separator, 8: the vacuum handling pipeline, 9:XY type power transmission platform, 10: motor, 11: pressure sensitive unit, 12: vavuum pump.
Claims (12)
1. artificial bio-prosthetic valve measurer for thickness, it is characterized in that, this device comprises: frame (1), vertical power transmission device (2), micro pressure inductive rod (3), gas-holder (4), air valve (5), gas transmission pipeline (6), gas-liquid separator (7), vacuum conveyer tube road (8), XY type power transmission platform (9), motor (10), pressure sensitive unit (11) and vacuum pump (12), wherein
Described vertical power transmission device (2) is fixed on the described frame (1);
Described micro pressure inductive rod (3) is fixed to described vertical power transmission device (2), and links to each other with described pressure sensitive unit (11);
Described gas transmission pipeline (6) links to each other the central tube of described gas-holder (4) with described micro pressure inductive rod (3), so that purge gas is supplied to described micro pressure inductive rod (3), and be provided with described air valve (5) and described gas-liquid separator (7) along described gas transmission pipeline (6);
Described XY type power transmission platform (9) is connected to described motor (10), is driven by described motor (10);
Described vacuum conveyer tube road (8) links to each other described XY type power transmission platform (9) with described vacuum pump (12), so as during to measure to vacuumizing between described XY type power transmission platform (9) and the artificial bio-prosthetic valve that is placed on it;
Wherein, by a plurality of sensing elements in the described micro pressure inductive rod (3) thickness that is placed on the artificial bio-prosthetic valve on the described XY type power transmission platform (9) is carried out multiple spot and dynamic formula measurement.
2. artificial bio-prosthetic valve measurer for thickness as claimed in claim 1, wherein, the induction end plane of the sensing element of described micro pressure inductive rod (3) is circular, and has the diameter of 1mm-100mm.
3. artificial bio-prosthetic valve measurer for thickness as claimed in claim 2, wherein, the diameter on the induction end plane of the sensing element of described micro pressure inductive rod (3) is 1mm-20mm.
4. artificial bio-prosthetic valve measurer for thickness as claimed in claim 1, wherein, the density that is provided with of sensing element is 5-20/cm in the described micro pressure inductive rod (3)
2
5. artificial bio-prosthetic valve measurer for thickness as claimed in claim 1, wherein, at least a in described gas-holder (4) stored nitrogen and the carbon dioxide.
6. artificial bio-prosthetic valve method for measuring thickness is characterized in that may further comprise the steps:
Artificial bio-prosthetic valve is placed on the XY type power transmission platform;
Utilize gas that artificial bio-prosthetic valve is purged;
To vacuumizing between artificial bio-prosthetic valve and the XY type power transmission platform, so that artificial bio-prosthetic valve is fixed and is attached on the XY type power transmission platform;
Make the micro pressure inductive rod contact artificial bio-prosthetic valve on the described XY type power transmission platform, the thickness of described artificial bio-prosthetic valve is carried out multiple spot and dynamic formula is measured by a plurality of sensing elements in the micro pressure inductive rod;
Measurement result is averaged, thereby obtain the average thickness of the artificial bio-prosthetic valve in measured zone.
7. artificial bio-prosthetic valve method for measuring thickness as claimed in claim 6, it also comprises step: move described XY type power transmission platform, with the thickness of the artificial bio-prosthetic valve of measuring zones of different.
8. artificial bio-prosthetic valve method for measuring thickness as claimed in claim 6, wherein, the induction end plane of the sensing element of described micro pressure inductive rod is circular, and has the diameter of 1mm-100mm.
9. artificial bio-prosthetic valve method for measuring thickness as claimed in claim 8, wherein, the diameter on the induction end plane of the sensing element of described micro pressure inductive rod is 1mm-20mm.
10. artificial bio-prosthetic valve method for measuring thickness as claimed in claim 6, wherein, the density that is provided with of sensing element is 5-20/cm in the described micro pressure inductive rod
2
11. artificial bio-prosthetic valve method for measuring thickness as claimed in claim 6, wherein, described gas is at least a in nitrogen and the carbon dioxide.
12. artificial bio-prosthetic valve method for measuring thickness as claimed in claim 6, wherein, described purge step continues the time of 10-200s.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100783173A CN102155906B (en) | 2011-03-25 | 2011-03-25 | Multipoint linked device and method for measuring thickness of bio-prosthetic valve |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100783173A CN102155906B (en) | 2011-03-25 | 2011-03-25 | Multipoint linked device and method for measuring thickness of bio-prosthetic valve |
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| CN102155906A true CN102155906A (en) | 2011-08-17 |
| CN102155906B CN102155906B (en) | 2012-10-31 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104034295A (en) * | 2014-06-05 | 2014-09-10 | 格力电器（武汉）有限公司 | Material thickness detection device and using method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1259776B1 (en) * | 2000-02-29 | 2005-06-08 | Edwards Lifesciences Corporation | Systems and methods for mapping and marking the thickness of bioprosthetic sheet |
| US7417749B1 (en) * | 2004-09-01 | 2008-08-26 | Electric Design To Market, Inc. | Method and apparatus for protecting an optical transmission measurement when sensing transparent materials |
| CN101435696A (en) * | 2008-12-08 | 2009-05-20 | 昆山思拓机器系统有限公司 | Device and method for measuring light sheet thickness |
| CN101839681A (en) * | 2009-03-18 | 2010-09-22 | 赫尔穆特费希尔有限责任公司电子及测量技术研究所 | Measure the method for stand and electrical control thereof |
-
2011
- 2011-03-25 CN CN2011100783173A patent/CN102155906B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1259776B1 (en) * | 2000-02-29 | 2005-06-08 | Edwards Lifesciences Corporation | Systems and methods for mapping and marking the thickness of bioprosthetic sheet |
| US7417749B1 (en) * | 2004-09-01 | 2008-08-26 | Electric Design To Market, Inc. | Method and apparatus for protecting an optical transmission measurement when sensing transparent materials |
| CN101435696A (en) * | 2008-12-08 | 2009-05-20 | 昆山思拓机器系统有限公司 | Device and method for measuring light sheet thickness |
| CN101839681A (en) * | 2009-03-18 | 2010-09-22 | 赫尔穆特费希尔有限责任公司电子及测量技术研究所 | Measure the method for stand and electrical control thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104034295A (en) * | 2014-06-05 | 2014-09-10 | 格力电器（武汉）有限公司 | Material thickness detection device and using method thereof |
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Effective date of registration: 20160411 Address after: 201203 Shanghai City Newton Road, Pudong New Area Zhangjiang hi tech Park No. 501 Patentee after: SHANGHAI MINIMALLY INVASIVE XINTONG MEDICAL TECHNOLOGY CO., LTD. Address before: 201203 Shanghai City Newton Road, Pudong New Area Zhangjiang hi tech Park No. 501 Patentee before: Shanghai MicroPort Medical Equipment (Group) Co., Ltd. |
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Effective date of registration: 20211125 Address after: 610000 Chengdu Tianfu international biological city, 618 Fenghuang Road, Shuangliu District, Chengdu, Sichuan Patentee after: Chengdu Xintuo Biotechnology Co.,Ltd. Address before: 201203, 501, Newton Road, Zhangjiang hi tech park, Shanghai, Pudong New Area Patentee before: SHANGHAI MICROPORT CARDIOFLOW MEDTECH Co.,Ltd. |