CN102121940A - Sampling process monitoring method and detection system - Google Patents
Sampling process monitoring method and detection system Download PDFInfo
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- CN102121940A CN102121940A CN2010105879746A CN201010587974A CN102121940A CN 102121940 A CN102121940 A CN 102121940A CN 2010105879746 A CN2010105879746 A CN 2010105879746A CN 201010587974 A CN201010587974 A CN 201010587974A CN 102121940 A CN102121940 A CN 102121940A
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Abstract
The invention discloses a sampling process monitoring method and a detection system. The sampling process monitoring method sequentially comprises the following steps of: moving a sampling gun to a suction nozzle area, wherein blank suction nozzles are arrayed in the suction nozzle area, and downwards moving the sampling gun to absorb one suction nozzle; moving the sampling gun to a monitoring area, and detecting whether the head of the sampling gun absorbs the suction nozzle or not in the monitoring area; if the suction nozzle is monitored to be absorbed by the head of the sampling gun, moving the sampling gun to a sample area to absorb a sample, and moving to a detection area to release the sample for detection; if the suction nozzle is monitored to be not absorbed by the head of the sampling gun, reassembling the suction nozzle; and after the sample is released, discarding the used suction nozzle, and returning the sampling gun to an initial position. In the invention, whether the sampling gun absorbs the suction nozzle or not is detected before the sampling gun absorbs the sample, the sampling gun automatically returns for reassembly of the suction nozzle if the sampling gun does not absorb the suction nozzle, and the advantages of no manual intervention, no sample omission during detection and convenience for operation are achieved.
Description
Technical field
The present invention relates to a kind of sampling process monitoring method and detection system, relate in particular to a kind of sampling process monitoring method and detection system that is applied to chemistry or biological aspect.
Background technology
Along with the development of chemistry or biological field detection means, and produce, increase that experiment needs test sample, the apparatus and method for of automatic monitoring also arises at the historic moment thereupon.
For instance, usually need in the biochemistry detection sample is carried out film-making dyeing, present automatic staining method and automatic staining machine adopt following steps usually:
Sampling gun is moved to the suction nozzle district, and the suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Sampling gun is moved to sample area, draw sample, move to detection zone release sample and detect;
Abandon used suction nozzle, sampling gun returns initial position, waits for new sampling instruction.
When but sometimes sampling gun picks up suction nozzle, suction nozzle is not picked up, or pick up the back in conjunction with not firm, suction nozzle comes off immediately, and the operation as usual of system's this moment, carry out successively and draw sample, discharge operations such as sample, when losing time, also incur loss through delay the comprehensive of testing result, often after a collection of dozens of and even up to a hundred sample detection are intact, which sample operating personnel need manually search does not have sampled rifle to draw and the release detection, arrange then to detect again, both wasted time and energy, but also easy omission sample.
At the problems referred to above, the someone proposes suction nozzle is detected in the industry, does not inhale when suction nozzle is arranged when detecting sampling gun, sends promptings such as acousto-optic, suspends simultaneously and detects, and reminds operating personnel to operate again.But this method needs the real-time execute-in-place of people, and suspends repeatedly and detect, and resets operation and loaded down with trivial details, inefficiency again.
Summary of the invention
The object of the present invention is to provide a kind of exhaustively automatic sampling process detection method that a kind of detection system of using said method is provided simultaneously.
For solving above-mentioned first technical matters, the invention provides a kind of sampling process monitoring method, may further comprise the steps successively:
Step 1: sampling gun is moved to the suction nozzle district, and the suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Step 2: sampling gun moves to monitoring section, and whether detection sampling gun rifle head is inhaled suction nozzle is arranged in monitoring section,
If monitor the suction of sampling gun rifle head suction nozzle is arranged, carry out step 3,
Do not have suction nozzle if monitor sampling gun rifle head, then execution in step 1;
Step 3: sampling gun is moved to sample area, draw sample, move to detection zone release sample and detect;
Step 4: abandon used suction nozzle, sampling gun returns initial position, waits to receive that new sampling detects instruction, execution in step 1.
Be different from nothing monitoring sampling or the simple warning and the time-out detection of prior art to no suction nozzle sampling gun, whether the present invention's detection sampling gun before drawing sample is inhaled suction nozzle is arranged, if do not inhale suction nozzle arranged, then return automatically and reinstall suction nozzle, need not artificial interference, detect and do not leak sample, easy to operate.
Wherein, whether detect sampling gun rifle head described in the step 2 in monitoring section inhales suction nozzle is arranged, the method that adopts is at monitoring section infrared detector to be set, whether infrared detector monitoring sampling gun lower end is present in the height below of setting, if the sampling gun lower end is present in the height below of setting, being judged as the suction of sampling gun rifle head has suction nozzle, if the sampling gun lower end is not present in the height below of setting, being judged as sampling gun rifle head does not have suction that suction nozzle is arranged.
Wherein, described sampling process monitoring method is a cell film-making dyeing course monitoring method,
Described step 3 is: sampling gun is moved to sample area, draw sample, move to detection zone release sample and detect, the recovery pin resorption in the other dyeing needle device that is provided with of sampling gun detects waste liquid;
Described step 4 is: be discharged into waste liquid in the waste collection device and abandon used suction nozzle, sampling gun returns initial position, waits to receive that new sampling detects instruction, execution in step 1.
Wherein, described suction nozzle is divided into stand-by suction nozzle district and standby suction nozzle district,
Described step 1 is divided into:
Step 1a: sampling gun is moved to stand-by suction nozzle district from initial position, and stand-by suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Step 1b: sampling gun is moved to standby suction nozzle district from monitoring section, and standby suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Step 1a and step 1b select one and carry out during execution;
Described step 2 is: sampling gun moves to monitoring section, and whether detection sampling gun rifle head is inhaled suction nozzle is arranged in monitoring section,
If monitor the suction of sampling gun rifle head suction nozzle is arranged, carry out step 3,
There is not suction nozzle if monitor sampling gun rifle head, then execution in step 1b;
Described step 4 is: abandon used suction nozzle, sampling gun returns initial position, waits to receive that new sampling detects instruction, execution in step 1a.
For solving second problem that the present invention proposes, the present invention also provides a kind of detection system, and described detection system comprises: sampling gun, drive unit, monitor, controller, suction nozzle frame, specimen holder, suction nozzle recovery area and detection zone;
Described suction nozzle frame is used to put blank suction nozzle, described specimen holder is used to put sample, described detection zone is used to detect the sample of release, and the rifle head and the blank suction nozzle of described sampling gun are suitable, is used for drawing and discharging sample behind the sampling gun socket suction nozzle, monitor is connected with controller, provide monitor signal to controller, controller is connected with drive unit, is used for accessory drive, drive unit and sampling gun join, and are used for mobile sampling gun;
When beginning to take a sample, described sampling gun moves to suction nozzle frame top, and moves in the scope of monitor monitors after picking up suction nozzle downwards, and whether monitor monitors sampling gun rifle head is inhaled suction nozzle is arranged, and gives controller with information feedback;
If controller judges that according to monitor information sampling gun rifle head inhales suction nozzle is arranged, sampling gun moves to specimen holder, draws sample, and moves to detection zone and discharge sample and detect;
If controller judges that according to monitor information sampling gun rifle head does not have suction nozzle, then whether sampling gun returns suction nozzle frame top and picks up suction nozzle again and move in the detector monitors scope monitoring sampling gun rifle head again and inhale suction nozzle is arranged, repeat above-mentioned steps and to the suction of sampling gun rifle head suction nozzle is arranged until monitor monitors, sampling gun moves to specimen holder, draw sample, and move to detection zone and discharge sample and detect;
After discharging sample, sampling gun is discarded into the suction nozzle recovery area with used suction nozzle.
Said detecting system can fully automatic operation, and does not exist and leak the sample problem, has reached the purpose that robotization detects.
Wherein, described monitor is an infrared detector, whether infrared detector monitoring sampling gun lower end is present in the height below of setting, if the sampling gun lower end is present in the height below of setting, then controller is judged as the suction of sampling gun rifle head suction nozzle, if the sampling gun lower end is not present in the height below of setting, then controller is judged as sampling gun rifle head does not have suction that suction nozzle is arranged.
Wherein, described detection system is a cell film-making coloring system, described cell film-making coloring system also is provided with dyeing needle device and waste liquid cylinder, described dyeing needle device is arranged on by the sampling gun, the dyeing needle device is provided with the recovery pin, after having discharged sample, reclaiming pin can the resorption waste liquid, and moves to waste liquid cylinder place and discharge waste liquid.
Wherein, described suction nozzle frame is divided into stand-by suction nozzle frame and standby suction nozzle frame;
If controller judges that according to monitor information sampling gun rifle head does not have suction nozzle, then sampling gun picks up suction nozzle to standby suction nozzle frame top;
Draw a new sample if desired, then sampling gun picks up suction nozzle to stand-by suction nozzle frame top.
Description of drawings
Fig. 1 is the described detection system planimetric map one of the specific embodiment of the invention;
Fig. 2 is the described detection system planimetric map two of the specific embodiment of the invention;
Fig. 3 is that the described infrared detector of the specific embodiment of the invention detects the determinating area synoptic diagram
Fig. 4 is the described detection system operation workflow of specific embodiment of the invention figure one;
Fig. 5 is the described detection system operation workflow of specific embodiment of the invention figure two.
Label declaration:
1, specimen holder 2, suction nozzle frame 21, stand-by suction nozzle frame 22, standby suction nozzle frame 3, slide frame 4, waste liquid cylinder 5, waste product box 6, infrared detector 7, sampling gun 8, suction nozzle
Embodiment
By describing technology contents of the present invention, structural attitude in detail, realized purpose and effect, give explanation below in conjunction with embodiment and conjunction with figs. are detailed.
See also Fig. 1 present embodiment a kind of detection system is provided, described detection system comprises: sampling gun, drive unit, monitor, controller, suction nozzle frame 2, specimen holder 1, suction nozzle recovery area and detection zone;
Described suction nozzle frame 2 is used to put blank suction nozzle, described specimen holder 1 is used to put sample, described detection zone is used to detect the sample of release, and (detection connotation of the present invention is the detection of broad sense, both can be that direct physicochemical property to sample detects, it also can be the preliminary preparation of being carried out for the detection data that obtain physical and chemical parameter, for example cell film-making dyeing etc.), the rifle head and the blank suction nozzle of described sampling gun are suitable, be used for drawing and discharging sample behind the sampling gun socket suction nozzle, monitor is connected with controller, provide monitor signal to controller, controller is connected with drive unit, be used for accessory drive, drive unit and sampling gun join, and are used for mobile sampling gun;
When beginning to take a sample, described sampling gun moves to suction nozzle frame 2 tops, and moves in the scope of monitor monitors after picking up suction nozzle downwards, and whether monitor monitors sampling gun rifle head is inhaled suction nozzle is arranged, and gives controller with information feedback;
If controller judges that according to monitor information sampling gun rifle head inhales and have suction nozzle, sampling gun to move to specimen holder 1, draw sample, and move to detection zone and discharge sample and detect; In detection system described in Fig. 1,2 is cell-stain apparatus, and detection zone is provided with slide frame 3, and sample is discharged on the slide on the slide frame 3.
If controller judges that according to monitor information sampling gun rifle head does not have suction nozzle, then whether sampling gun returns suction nozzle frame 2 tops and picks up suction nozzle again and move in the detector monitors scope monitoring sampling gun rifle head again and inhale suction nozzle is arranged, repeat above-mentioned steps and to the suction of sampling gun rifle head suction nozzle is arranged until monitor monitors, sampling gun moves to specimen holder 1, draw sample, and move to detection zone and discharge sample and detect;
After discharging sample, sampling gun is discarded into suction nozzle recovery area (being waste product box 5) with used suction nozzle.
Therefore the detection system of present embodiment is when detecting, and its operation workflow may further comprise the steps referring to Fig. 4:
Step 1: sampling gun is moved to suction nozzle district (suction nozzle frame zone), and the suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Step 2: sampling gun moves to monitoring section (zone of monitor monitors), and whether detection sampling gun rifle head is inhaled suction nozzle is arranged in monitoring section,
If monitor the suction of sampling gun rifle head suction nozzle is arranged, carry out step 3,
Do not have suction nozzle if monitor sampling gun rifle head, then execution in step 1;
Step 3: sampling gun is moved to sample area (specimen holder zone), draw sample, move to detection zone release sample and detect;
Step 4: abandon used suction nozzle (being discarded into the sample recovery area), sampling gun returns initial position, waits to receive that new sampling detects instruction, execution in step 1.
In another embodiment of the present invention, as shown in Figure 2, described monitor is an infrared detector 6, whether infrared detector 6 monitoring sampling gun lower ends are present in the height below of setting, if the sampling gun lower end is present in the height below of setting, then controller is judged as the suction of sampling gun rifle head suction nozzle, if the sampling gun lower end is not present in the height below of setting, then controller is judged as sampling gun rifle head does not have suction that suction nozzle is arranged.
The height of setting can be as shown in Figure 3, be lower than sampling gun 7 ends that do not connect suction nozzle, but be higher than the end that connects suction nozzle 8 back sampling guns again, it is position between dotted line c shown in Figure 3, the d, detected object and exist in this altitude range, infrared detector 6 sends to controller with signal, and controller will be judged as sampling gun rifle head and inhale suction nozzle is arranged, do not have suction nozzle to be adsorbed on the sampling gun otherwise then be judged as, make sampling gun ressemble suction nozzle driver.
In other embodiments, infrared detector 6 also can be substituted by laser detector etc.
In another embodiment of the present invention, as shown in Figure 1, 2, described detection system is a cell film-making coloring system, described cell film-making coloring system also is provided with dyeing needle device and waste liquid cylinder 4, the dyeing needle device is arranged on by the sampling gun, and the dyeing needle device is provided with the recovery pin, after having discharged sample, reclaiming pin can the resorption waste liquid, and moves to waste liquid cylinder place and discharge waste liquid.
So the step of the foregoing description is further abundant be:
Described step 3 is: sampling gun is moved to sample area, draw sample, move to detection zone release sample and dye, the recovery pin resorption dyeing waste liquid in the other dyeing needle device that is provided with of sampling gun;
Step 4: be discharged into waste liquid in the waste collection device and abandon used suction nozzle, sampling gun returns initial position, waits to receive that new sampling detects instruction, execution in step 1.
Present embodiment mainly is in order to adapt to biochemistry detection equipment such as cell-stain apparatus, in dyeing course, when discharging sample, equipment also will discharge some coloring agents etc., after release finishes, also need the operation of a resorption, therefore before handling next sample, the waste liquid of resorption can be discharged.Discharge waste liquid and the sequence of operation that abandons suction nozzle without limits, can discharge waste liquid earlier, also can abandon suction nozzle earlier.
As the further improvement to above-mentioned each embodiment, as shown in Figure 2, described suction nozzle frame is divided into stand-by suction nozzle frame 21 and standby suction nozzle frame 22;
If controller judges that according to monitor information sampling gun rifle head does not have suction nozzle, then sampling gun picks up suction nozzle to standby suction nozzle frame 22 tops;
Draw a new sample if desired, then sampling gun picks up suction nozzle to stand-by suction nozzle frame 21 tops.
Its operation is improved to respect to the first embodiment of the present invention:
Step 1a: sampling gun is moved to stand-by suction nozzle district (stand-by suction nozzle frame zone) from initial position, and stand-by suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Step 1b: sampling gun is moved to standby suction nozzle district (standby suction nozzle frame zone) from monitoring section, and standby suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Step 1a and step 1b select one and carry out during execution;
Described step 2 is: sampling gun moves to monitoring section, and whether detection sampling gun rifle head is inhaled suction nozzle is arranged in monitoring section,
If monitor the suction of sampling gun rifle head suction nozzle is arranged, carry out step 3,
There is not suction nozzle if monitor sampling gun rifle head, then execution in step 1b;
Described step 4 is: abandon used suction nozzle, sampling gun returns initial position, waits to receive that new sampling detects instruction, execution in step 1a.
Referring to the flow process in the accompanying drawing 5.
Such benefit is, can prepare stand-by suction nozzle according to the sample number, and detect finish after, only need to check the number of variations of standby suction nozzle, just know to have and repeat to assemble suction nozzle several times.
The above only is embodiments of the invention; be not so limit claim of the present invention; every equivalent structure or equivalent flow process conversion that utilizes instructions of the present invention and accompanying drawing content to be done; or directly or indirectly be used in other relevant technical fields, all in like manner be included in the scope of patent protection of the present invention.
Claims (8)
1. a sampling process monitoring method is characterized in that, may further comprise the steps successively:
Step 1: sampling gun is moved to the suction nozzle district, and the suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Step 2: sampling gun moves to monitoring section, and whether detection sampling gun rifle head is inhaled suction nozzle is arranged in monitoring section,
If monitor the suction of sampling gun rifle head suction nozzle is arranged, carry out step 3,
Do not have suction nozzle if monitor sampling gun rifle head, then execution in step 1;
Step 3: sampling gun is moved to sample area, draw sample, move to detection zone release sample and detect;
Step 4: abandon used suction nozzle, sampling gun returns initial position, waits to receive that new sampling detects instruction, execution in step 1.
2. sampling process monitoring method according to claim 1, it is characterized in that, whether detect sampling gun rifle head described in the step 2 in monitoring section inhales suction nozzle is arranged, the method that adopts is at monitoring section infrared detector to be set, whether infrared detector monitoring sampling gun lower end is present in the height below of setting, if the sampling gun lower end is present in the height below of setting, be judged as the suction of sampling gun rifle head suction nozzle is arranged, if the sampling gun lower end is not present in the height below of setting, being judged as sampling gun rifle head does not have suction that suction nozzle is arranged.
3. sampling process monitoring method according to claim 1 is characterized in that,
Described sampling process monitoring method is a cell film-making dyeing course monitoring method,
Described step 3 is: sampling gun is moved to sample area, draw sample, move to detection zone release sample and detect, the recovery pin resorption in the other dyeing needle device that is provided with of sampling gun detects waste liquid;
Described step 4 is: be discharged into waste liquid in the waste collection device and abandon used suction nozzle, sampling gun returns initial position, waits to receive that new sampling detects instruction, execution in step 1.
4. according to any described sampling process monitoring method of claim 1 to 3, it is characterized in that described suction nozzle is divided into stand-by suction nozzle district and standby suction nozzle district,
Described step 1 is divided into:
Step 1a: sampling gun is moved to stand-by suction nozzle district from initial position, and stand-by suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Step 1b: sampling gun is moved to standby suction nozzle district from monitoring section, and standby suction nozzle district is arranged with blank suction nozzle, and sampling gun moves downwards, picks up suction nozzle;
Step 1a and step 1b select one and carry out during execution;
Described step 2 is: sampling gun moves to monitoring section, and whether detection sampling gun rifle head is inhaled suction nozzle is arranged in monitoring section,
If monitor the suction of sampling gun rifle head suction nozzle is arranged, carry out step 3,
There is not suction nozzle if monitor sampling gun rifle head, then execution in step 1b;
Described step 4 is: abandon used suction nozzle, sampling gun returns initial position, waits to receive that new sampling detects instruction, execution in step 1a.
5. a detection system is characterized in that, described detection system comprises: sampling gun, drive unit, monitor, controller, suction nozzle frame, specimen holder, suction nozzle recovery area and detection zone;
Described suction nozzle frame is used to put blank suction nozzle, described specimen holder is used to put sample, described detection zone is used to detect the sample of release, and the rifle head and the blank suction nozzle of described sampling gun are suitable, is used for drawing and discharging sample behind the sampling gun socket suction nozzle, monitor is connected with controller, provide monitor signal to controller, controller is connected with drive unit, is used for accessory drive, drive unit and sampling gun join, and are used for mobile sampling gun;
When beginning to take a sample, described sampling gun moves to suction nozzle frame top, and moves in the scope of monitor monitors after picking up suction nozzle downwards, and whether monitor monitors sampling gun rifle head is inhaled suction nozzle is arranged, and gives controller with information feedback;
If controller judges that according to monitor information sampling gun rifle head inhales suction nozzle is arranged, sampling gun moves to specimen holder, draws sample, and moves to detection zone and discharge sample and detect;
If controller judges that according to monitor information sampling gun rifle head does not have suction nozzle, then whether sampling gun returns suction nozzle frame top and picks up suction nozzle again and move in the detector monitors scope monitoring sampling gun rifle head again and inhale suction nozzle is arranged, repeat above-mentioned steps and to the suction of sampling gun rifle head suction nozzle is arranged until monitor monitors, sampling gun moves to specimen holder, draw sample, and move to detection zone and discharge sample and detect;
After discharging sample, sampling gun is discarded into the suction nozzle recovery area with used suction nozzle.
6. detection system according to claim 5, it is characterized in that, described monitor is an infrared detector, whether infrared detector monitoring sampling gun lower end is present in the height below of setting, if the sampling gun lower end is present in the height below of setting, then controller is judged as the suction of sampling gun rifle head suction nozzle, if the sampling gun lower end is not present in the height below of setting, then controller is judged as sampling gun rifle head does not have suction that suction nozzle is arranged.
7. detection system according to claim 6, it is characterized in that, described detection system is a cell film-making coloring system, described cell film-making coloring system also is provided with dyeing needle device and waste liquid cylinder, described dyeing needle device is arranged on by the sampling gun, and the dyeing needle device is provided with the recovery pin, after having discharged sample, reclaiming pin can the resorption waste liquid, and moves to waste liquid cylinder place and discharge waste liquid.
8. according to any described detection system of claim 5 to 7, it is characterized in that described suction nozzle frame is divided into stand-by suction nozzle frame and standby suction nozzle frame;
If controller judges that according to monitor information sampling gun rifle head does not have suction nozzle, then sampling gun picks up suction nozzle to standby suction nozzle frame top;
Draw a new sample if desired, then sampling gun picks up suction nozzle to stand-by suction nozzle frame top.
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CN103558075A (en) * | 2013-10-10 | 2014-02-05 | 广州安必平自动化检测设备有限公司 | Photoelectric detection mechanism for cell-stain apparatus |
CN109297796A (en) * | 2018-12-19 | 2019-02-01 | 孝感市森茂激光数控设备有限公司 | A kind of sampling of automatic sedimentation pelleter and dye liquor injection device and method |
CN110354932A (en) * | 2019-08-06 | 2019-10-22 | 广西曼森生物科技有限公司 | A kind of automatic fluid operating platform |
CN112938490A (en) * | 2021-03-17 | 2021-06-11 | 苏州华兴源创科技股份有限公司 | Suction nozzle spacing adjusting method and system |
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CN112938490B (en) * | 2021-03-17 | 2023-02-17 | 苏州华兴源创科技股份有限公司 | Suction nozzle spacing adjusting method and system |
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Application publication date: 20110713 |