CN102119969A - Medicine for treating eczema and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating eczema, which consists of the following components in part by weight: 40 to 60 parts of sweet wormwood herb, 40 to 60 parts of mongolian dandelion herb and 30 to 50 parts of belvedere fruit. The preparation method comprises the following steps of: washing the components serving as Chinese medicinal raw materials by using clear water; adding water in an amount which is 2 times the total weight of the Chinese medicinal raw materials; warming until a boiling point is reached; decocting for 20 minutes; filtering off liquid; continuously decocting for three times accordingly; mixing decoction liquid which is obtained by the three-time decoction; filtering and concentrating until medicinal liquid with relative density of 1.05 to 1.07 is obtained; adding an antiseptic; and bottling and sterilizing to obtain a liniment. The medicine for treating the eczema has the advantages of quick response, good curative effect, a small number of readily available combined medicine materials, no toxic or side effect, no allergic reaction and simple preparation process.

Description

Medicine of treatment eczema and preparation method thereof

Technical field

The invention belongs to the Chinese medicine external used medicine, specifically a kind of medicine for the treatment of eczema and preparation method thereof.

Background technology

Eczema is a kind of common epidermis that is caused by multiple internal and external factor and the inflammatory skin disease of high dermis, and it is generally acknowledged with allergy has certain relation.Eczema accounts for the first place in the dermatosis spectrum, of all ages section, any age all can take place.Its clinical manifestation has characteristics such as symmetry, exudative, pruritus, pleomorphism and recurrent.Also be a kind of allergic inflammation dermatoses with the erythra multiformity, be symmetrically distributed, violent pruritus shows effect, easily develops into the chronic feature that is repeatedly.Can betide any position of any age, but recur or aggravate the winter of being everlasting the tendency of oozing out be arranged any season, the chronic course of disease, easily outbreak repeatedly.Because skin ulceration, the damaged skin area of eczema are bigger, pain, scratchiness happen occasionally, and bring great misery to the patient.Because of the primary disease treatment is not easy to cure, the patient spends more, and it is very heavy bringing burden economically to family.Therefore, excavate spend less, the traditional Chinese medical science medicine of eutherapeutic treatment eczema has important practical sense.

Summary of the invention

The purpose of this invention is to provide a kind of to treatment eczema instant effect, medicine that cure rate is high and preparation method thereof.

A kind of medicine for the treatment of eczema, form by following parts by weight of traditional Chinese medicines raw material:

Herba Artemisiae Annuae 40-60

Herba Taraxaci 40-60

Fructus Kochiae 30-50.

The preferred parts by weight of each raw material of Chinese medicine are in the medicine of the present invention:

Herba Artemisiae Annuae 45-50

Herba Taraxaci 45-50

Fructus Kochiae 40-45.

Above-mentioned each component is made the medicine for external use agent according to a conventional method, and the preferred dosage form of the present invention is a liniment.

The concrete preparation method of medicine liniment of the present invention is as follows:

Take by weighing each raw material of Chinese medicine by above-mentioned parts by weight, rinse well with water purification, add the water of Chinese medicine gross weight twice, be heated to and boil, decocted 20 minutes, filter out liquid, decoct three times so continuously, merge 3 times decocting liquid, be condensed into the medicinal liquid of relative density 1.05～1.07 after the filtration, add antiseptic, liniment is made in the bottling sterilization.

Compatibility of drugs medical material of the present invention is few and be easy to get, and manufacturing process is easy, treatment eczema instant effect, and good effect, nontoxic secondary the use do not find that allergic phenomena takes place.

Drug therapy eczema of the present invention is carried out clinical observation research.

The case diagnosis standard:

Western medicine diagnose standard: (1) acute eczema: acute attack can betide any position of health, general of whole body or be confined to a place, the normal symmetrical distribution, erythra is pleomorphism, visible erythema, pimple, papulovesicle, vesicle, erosion, scratches trace, incrustation etc., ooze out obviously acute pruritus.(2) subacute eczema: acute eczema malpractice or processing differentiation in time, erythra pimple, squama, incrustation are main, as seen ooze out acute pruritus on a small quantity.(3) chronic eczema: more do not form by acute or subacute outbreak repeatedly, also can be chronic eczema at the beginning, skin lesion is limited to a place or many places more, limitation or general property infiltration plumpness, be dim brown or brown pigmentation is calm, go up coated with a small amount of squama or be lichenification.

Differential diagnosis in tcm: the morbidity of (1) warm contamination card is anxious, and Pi Sun inflammation is red scorching hot, and pruritus does not have not, and broken Tianjin spilling water is in a moment along opening restlessness and thirst, dry stool, yellowish urine, red tongue, yellow fur or yellow greasy, slippery and rapid pulse.(2) the insufficiency of the spleen wet card that accumulates is fallen ill than silk ribbon attached to an official seal or a medal, and the course of disease is longer, and erythra is main through pimple and papulovesicle, and color is lighter dark, or squama is arranged, and has a little Tianjin water excessive after pruritus is scratched, anorexia and loose stool, and clear urine in large amounts or little Huang, pale tongue, white and thin fur or greasy, soft pulse is sliding.(3) with the passing of time the syndrome of wind and dryness due to blood deficiency course of disease does not heal repeatedly, the coarse plumpness of skin lesion, and play is itched, and scratches the trace desquamation, and idol plays red foxtail millet, pale tongue, thin fur, thready and stringy pulse.

Test case standard: (1) includes the case standard in: meet primary disease diagnostic criteria and differential diagnosis in tcm person, can include the test case in.(2) get rid of the case standard: the A age below 18 one full year of life or more than 65 one full year of life, trimester of pregnancy or women breast-feeding their children, to this medicine allergy sufferers; B took steroid hormone in nearly two weeks, used antihistaminic class medicine or the external person that crosses the corticosteroid formulations in the nearly week; C is associated with serious primary disease such as liver, kidney and hemopoietic system, psychotic; The all standards of including in that do not meet of D, not medication in accordance with regulations can't be judged that curative effect or data are not congruent to affect the treatment or safety judgement person.

Curative effect determinate standard: the therapeutic evaluation of (1) efficacy determination method is to distribute and the total mark of stadium weighting calculates curative effect and judges with pruritus degree, erythra.Curative effect rate=(total mark before treating-treatment back total mark)/total mark * 100% before treating.(2) efficacy determination A recovery from illness: skin lesion all disappears, the pruritus transference cure, and the curative effect rate reaches 100%; The B produce effects: the big portion of skin lesion disappears, and pruritus obviously alleviates, and the curative effect rate reaches 70%; C is effective: skin lesion partly disappears, and the pruritus symptom makes moderate progress, and the curative effect rate reaches 30%; D is invalid: skin lesion disappears not obvious, and pruritus does not see and alleviate or clinical symptoms is counter sees deterioration that the curative effect rate does not reach 30%.

Determine that according to clinical experience the medicament using method is: liniment being coated in the affected part, smearing 3 to 5 times in 1st, was a course of treatment in one week to the acute eczema patient, and patients with chronic eczema January is a course of treatment.

The acute eczema patient of Pass Test case standard is totally 121 examples, wherein male 67 examples, women 54 examples, 36.71 ± 7.25 one full year of life of mean age, patients with chronic eczema is totally 104 examples, wherein male 49 examples, women 55 examples, 42.53 ± 6.47 one full year of life of mean age, average 2.28 ± 1.62 years of medical history, therapeutic effect such as table 1:

Table 1 eczema treatment effect

Curative effect determinate standard	Recovery from illness	Produce effects	Effectively	Invalid	Add up to
						The acute eczema example	48	55	13	5	121
Percentage ratio	39.67	45.45	10.74	4.13	100
						The chronic eczema example	87	11	4	2	104
Percentage ratio	83.65	10.58	3.85	1.92	100

The treatment cycle of medicine of the present invention is shorter than general Western medicine, and little to the side effect of human body.Treatment total effective rate (recovery from illness+produce effects+effective) to acute eczema reaches 95.87%, and cure rate reaches 39.67%; Treatment total effective rate (recovery from illness+produce effects+effective) to chronic eczema reaches 98.08%, and cure rate reaches 83.65%.

The specific embodiment

Embodiment 1

Get Herba Artemisiae Annuae 5Kg, Herba Taraxaci 5Kg and Fructus Kochiae 4Kg and pack in the extraction pot, rinse well, add 28Kg water then with water purification, heat to boiling point, decocted solid-liquid separation 20 minutes, in solid phase, add 28Kg water again, heat, decocted 20 minutes to boiling point, solid-liquid separation adds 28Kg water once more in solid phase, heat to boiling point, decocted 20 minutes, solid-liquid separation merges 3 times decocting liquid, be condensed into the medicinal liquid of relative density 1.05～1.07 after the filtration, add antiseptic according to a conventional method, the bottling sterilization is product.

Embodiment 2

Getting Herba Artemisiae Annuae 4.5Kg, Herba Taraxaci 4.5Kg and Fructus Kochiae 3.5Kg packs in the extraction pot, rinse well with water purification, add 25Kg water then, heat to boiling point, decocted solid-liquid separation 20 minutes, in solid phase, add 25Kg water again, heat to boiling point, decocted solid-liquid separation 20 minutes, in solid phase, add 25Kg water once more, heat to boiling point, decocted solid-liquid separation 20 minutes, merge 3 times decocting liquid, be condensed into the medicinal liquid of relative density 1.05～1.07 after the filtration, add antiseptic according to a conventional method, the bottling sterilization is product.

Claims (4)

1. medicine for the treatment of eczema, form by following parts by weight of traditional Chinese medicines raw material:

Herba Artemisiae Annuae 40-60

Herba Taraxaci 40-60

Fructus Kochiae 30-50.

2. the medicine of treatment eczema according to claim 1 is characterized in that the parts by weight of each raw material of Chinese medicine are:

Herba Artemisiae Annuae 45-50

Herba Taraxaci 45-50

Fructus Kochiae 40-45.

3. the medicine of treatment eczema according to claim 1 and 2 is characterized in that described medicine is made liniment.

4. the preparation method of the medicine of the described treatment eczema of claim 3, be that each raw material of Chinese medicine of above-mentioned parts by weight is rinsed well with water purification, add the water of Chinese medicine gross weight twice, be heated to and boil, decocted 20 minutes, filter out liquid, decoct three times so continuously, merge 3 times decocting liquid, be condensed into the medicinal liquid of relative density 1.05～1.07 after the filtration, add antiseptic, liniment is made in the bottling sterilization.