CN102114144A - Traditional Chinese medicine for treating diabetic peripheral neuropathy - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating diabetic peripheral neuropathy, which belongs to the field of traditional Chinese medicines for treating diabetes, and has the purposes of good effect and quick effect. The traditional Chinese medicine is prepared from the raw materials of red paeony roots, white paeony roots, tribulus terrestris, lucid ganoderma, pseudo-ginseng, salvia miltiorrhiza, oriental waterplantain rhizome, and the like. The traditional Chinese medicine has the effects of strengthening the body resistance to consolidate the constitution, invigorating Qi and nourishing blood, promoting blood circulation and removing blood stasis, and clearing damp and promoting diuresis. The traditional Chinese medicine has the advantages of obvious effect, exact effect and quicker effect.

Description

A kind of Chinese medicine for the treatment of diabetic peripheral neuropathy

Technical field

The invention belongs to the field of Chinese medicines of treatment diabetes.

Background technology

Diabetic peripheral neuropathy is one of common complication of diabetes, mainly involves people's somatic nerve and nervus motorius, is due to the microangiopathies that causes of diabetes.About 90% above diabetics all can take place in the later stage, usually with diabetic nephropathy, diabetic renal papillary necrosis coexistence, was called three diseases (three diseases are both diabetic microvascular complication).At present, be intended to treat the Chinese medicine of diabetic peripheral neuropathy, the deficiency that has two aspects: the one, effect is obvious inadequately, the 2nd, it is slower to take effect, owing to can not get the treatment of active drug for a long time, so that pain, numbness, paraesthesia that large quantities of diabetic peripheral neuropathy patients stand limbs for a long time, quality of life descends, and the patient is dissatisfied to this.

At problem set forth above, the invention provides a kind of Chinese medicine for the treatment of diabetic peripheral neuropathy, effect was obvious inadequately during it can solve and treat in the past, the slower problem that takes effect, effective, instant effect, it is remarkable to have effect, drug effect is definite, the advantage of quick result.

Summary of the invention

The present invention is achieved through the following technical solutions:

1, a kind of Chinese medicine for the treatment of diabetic peripheral neuropathy adopts the raw material of Chinese medicine preparation, and filling a prescription is (by weight):

Radix Paeoniae Rubra 5---15 parts of 15 portions of Radix Paeoniae Albas 6---18 parts of Fructus Atriplicis Sibiricaees 5---

Ganoderma 6---18 parts of 18 portions of Radix Notoginseng 3---9 parts of Radix Salviae Miltiorrhizaes 6---

Rhizoma Alismatis 5---15 parts

The Chinese medicine of this treatment diabetic peripheral neuropathy is made by following method:

(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is as follows: Ganoderma is broken into graininess, cross 40 mesh sieves →, concentrate → mixed, leave standstill 10-12 hours, centrifugal → as to add 75% ethanol with 95% ethanol of 3 times of volumes with hot water (95 ℃) lixiviate of 1:20 → lixiviating solution decompression, precipitate polysaccharide → dry the ganoderan extract fine powder;

(2) by above-mentioned weight ratio, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Fructus Atriplicis Sibiricae, Radix Salviae Miltiorrhizae, Rhizoma Alismatis are extracted through conventional water extraction process, make extract extractum fine powder;

(3) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, make Chinese medicine granules, capsule, tablet with above-mentioned (1), (2) two kinds of extract fine powders.

The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We think that diabetic peripheral neuropathy in essence, is somatic nerve, motorial microangiopathies at research.The cause of disease mainly is the diabetics hypoimmunity, and the deficiency of YIN is scorching, qi depression to blood stasis, and blood is sticky, causes limb microcirculation disturbance, due to neural mistake is supported.So the treatment of this disease must hold on to " setting upright ", this key link of enhancing immunity, supplementing QI and nourishing YIN, blood circulation promoting and blood stasis dispelling.Among the we, Ganoderma, Radix Paeoniae Alba the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, nourishing the kidney and liver, enhancing human body immunity power; Radix Salviae Miltiorrhizae, Radix Notoginseng nourshing blood and promoting blood circulation, blood-activating analgetic; Ganoderma, the Radix Paeoniae Alba and Radix Salviae Miltiorrhizae, Radix Notoginseng are associated with, the prosperous hemapodium of gas, and " removing " of immunity and " reparation " effect promote blood clean, no longer sticky, rich mobile, promote blood vessel stasis of blood plug to alleviate, microcirculation improves, and the blood supply of trophic nerve is plentiful abundant, and this is this sick key link of treatment.Be aided with the Radix Paeoniae Rubra clearing away heat and cooling blood, eliminating stasis to stop pain; The Rhizoma Alismatis promoting diuresis to eliminate damp pathogen, inducing diuresis to remove edema, carrying it " not Lu " can " the tonifying deficiency five kinds of over strain be removed the five internal organs feeling of fullness, plays cloudy gas, stopping leak essence, quench one's thirst "; The Fructus Atriplicis Sibiricae suppressing the hyperactive liver, invigorate blood circulation, dispel the wind, modern pharmacological research, Fructus Atriplicis Sibiricae has the hemorheology of improvement, alleviates the microcirculation disturbance effect.All medicine compatibilities bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, and blood circulation promoting and blood stasis dispelling, the merit of eliminating damp-heat, effective, instant effect, it is remarkable to have effect, and drug effect is definite, the advantage of quick result.

The specific embodiment

By following embodiment the present invention is done and to specify:

1, get following prescription (weight is unit by gram):

The Radix Paeoniae Rubra 50 gram Radix Paeoniae Albas 60 gram Fructus Atriplicis Sibiricaees 50 grams

Ganoderma 60 gram Radix Notoginseng 30 gram Radix Salviae Miltiorrhizaes 60 grams

Rhizoma Alismatis 50 grams

Weight is extracted Ganoderma with decoction and alcohol sedimentation technique in accordance with regulations; With conventional water extraction process Radix Paeoniae Rubra, the Radix Paeoniae Alba, Rhizoma Alismatis, Radix Salviae Miltiorrhizae, Fructus Atriplicis Sibiricae are extracted, make extract fine powder 66 grams altogether, Radix Notoginseng is ground into fine powder, mix with said extracted thing fine powder, stir, make fine particle, the capsule of packing into No. 0, make 342 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

2, get following prescription (weight is unit by gram):

The Radix Paeoniae Rubra 100 gram Radix Paeoniae Albas 120 gram Fructus Atriplicis Sibiricaees 100 grams

Ganoderma 120 gram Radix Notoginseng 60 gram Radix Salviae Miltiorrhizaes 120 grams

Rhizoma Alismatis 100 grams

By above-mentioned same method, make 685 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

3, get following prescription (weight is unit by gram):

The Radix Paeoniae Rubra 150 gram Radix Paeoniae Albas 180 gram Fructus Atriplicis Sibiricaees 150 grams

Ganoderma 180 gram Radix Notoginseng 80 gram Radix Salviae Miltiorrhizaes 180 grams

Rhizoma Alismatis 150 grams

By above-mentioned same method, make 992 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

4, get following prescription (by weight):

5 parts of 7 parts of Fructus Atriplicis Sibiricaees of 5 portions of Radix Paeoniae Albas of Radix Paeoniae Rubra

7 parts of 3 parts of Radix Salviae Miltiorrhizaes of 7 portions of Radix Notoginseng of Ganoderma

5 parts of Rhizoma Alismatis

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

5, get following prescription (by weight):

14 parts of 16 parts of Fructus Atriplicis Sibiricaees of 14 portions of Radix Paeoniae Albas of Radix Paeoniae Rubra

16 parts of 7 parts of Radix Salviae Miltiorrhizaes of 16 portions of Radix Notoginseng of Ganoderma

14 parts of Rhizoma Alismatis

By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.

Clinical data:

The present invention is an example with traditional Chinese medical science diabetic peripheral neuropathy, through 9 routine clinical observations.Selecting traditional Chinese medical science diabetic peripheral neuropathy is standard: diabetics has a delicate constitution, health is weak; Xerosis cutis, numbness of hands and feet, pain; Meropresthesia, tingle, the sense of ant row, burning sensation.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 6 examples, women's 3 examples do not have other serious disease, and the age is 46 years old-79 years old, 61.3 years old mean age.

Efficacy determination:

1, produce effects: body constitution strengthens, and extremity are strong; Numbness of hands and feet, pain are obviously alleviated; The sensation of pricking of meropresthesia, the sense of ant row, burning sensation disappearance or obviously alleviation.

2, effective: on one's body energetically, numb limbs and tense tendons, pain and abnormal sensory are alleviated to some extent.

3, invalid: the disease no change.

During clinical experiment, except that necessary antidiabetic drug is taken as usual, withdraw other medicines and health nutrient.Take Chinese medicinal capsule of the present invention, observing 3 months is a course of treatment.Instructions of taking: every day 2 times, each 4 capsules, every capsules include Chinese medicine fine powder and extract 0.28 gram, warm water delivery service after meal, symptom promptly has alleviation after 1 month, take 3 months after, symptom is obviously improved.9 philtrums of clinical experiment, produce effects 4 people, effective 4 people, invalid 1 people, total effective rate 88.8%.

Claims (1)

1. Chinese medicine for the treatment of diabetic peripheral neuropathy, it is characterized in that: it is to make with the component of following weight ratio: Radix Paeoniae Rubra 5---15 parts, the Radix Paeoniae Alba 6---18 parts, Fructus Atriplicis Sibiricae 5---15 parts, Ganoderma 6---18 parts, Radix Notoginseng 3---9 parts, Radix Salviae Miltiorrhizae 6---18 parts, Rhizoma Alismatis 5---15 parts.