CN102078422B - External ointment used for changing medicine for anal fistula postoperative wound surface and preparation method thereof - Google Patents
External ointment used for changing medicine for anal fistula postoperative wound surface and preparation method thereof Download PDFInfo
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- CN102078422B CN102078422B CN2010106086991A CN201010608699A CN102078422B CN 102078422 B CN102078422 B CN 102078422B CN 2010106086991 A CN2010106086991 A CN 2010106086991A CN 201010608699 A CN201010608699 A CN 201010608699A CN 102078422 B CN102078422 B CN 102078422B
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Abstract
The invention relates to an external ointment used for changing medicine for an anal fistula postoperative wound surface and a preparation method thereof. The external ointment is prepared from the following raw materials in parts by weight: 50 parts of balm, 15 parts of yellow wax, 4 parts of vermilion powder, 4 parts of carbonized hair, 1 part of pepper, 2 parts of calomel, 5 parts of aluminum powder and 1 part of amber powder. The preparation method comprises the following steps of: placing the balm into a heated boiler; heating with soft fire; boiling and then adding the carbonized hair; placing the pepper into the boiler after the carbonized hair is turned into yellow, taking out the pepper and the carbonized hair one minute later; then placing the yellow wax into the boiler; stopping heating at the moment; filtering the substances in the boiler into a container after the yellow wax is dissolved; and cooling and then placing the calomel, the aluminum powder, the amber powder and the vermilion powder into the container to be uniformly stirred. The ointment provided by the invention has powerful efficacy of eliminating necrotic tissues, promoting tissue regeneration, astringing sores, detoxificating and relieving pain so as to achieve the purpose of promoting wound surface healing. Compared with the traditional external ointment for changing medicine and cleaning the wound surface, the healing time is shortened, the curative effect is obvious. The preparation method is simple and conveniently utilized.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly relate to a kind of anal fistula after operation wound surface external-applied ointment and preparation method thereof of changing dressings that is used for.
Background technology
Anal fistula is to betide near the anus and the fistula of rectum bottom, is common anal and intestinal disease.Motherland's traditional medicine is thought: though hemorrhoids disease is the foreign aggression skin infection, from the theory of Chinese medical science angle, its cause of disease, pathogenesis still be unable to do without six climate exopathogens and do harm to.You Yifeng, wet, dry, heat four is evil in close relations.This goes hand in hand again clinically, and " doctor mirror " at all times said: " husband hemorrhoid complicated by anal fistula person has hemorrhoid person also inside and outside the anorectal limit ... be to cause it by wind, wet, dry, heat seal." " record of medical science telepathy " institute's cloud: " damp and hot gas is led also, gives birth to fungus as tree, must give birth to because of damp and hot ".The damp and hot resistance anus that accumulates, meridians intercept, and the QI and blood retardance is prone to into anal abscess.Therefore, cure this type of, should as long as old complaint is removed, can reach therapeutic purposes from its cause of disease, pathology.
In the prior art, treatment hemorrhoid complicated by anal fistula class disease mainly adopts operative treatment and two kinds of methods of Drug therapy.After the surgical incision and drainage,, need constantly change dressings owing to be contamination of incision.And adopting traditional dressing change, wound healing time is long, generally about January, reaches the several months sometimes, causes very big misery to the patient, both expensive.
Summary of the invention
The objective of the invention is to overcome the defective of above-mentioned prior art, a kind of wound healing is fast, therapeutic effect good, expense is low anal fistula after operation wound surface change dressings external-applied ointment and method for preparing are provided.
The scheme that the present invention solves the problems of the technologies described above is following: a kind of anal fistula after operation wound surface external-applied ointment of changing dressings that is used for, process by weight ratio by following raw material: Oleum sesami 50-100 part, Cera Flava 15-30 part, Vermilion powder 4-10 part, Crinis Carbonisatus 4-10 part, Pericarpium Zanthoxyli 1-2 part, Calomelas 2-5 part, aluminium powder 5-10 part, Succinum powder 1-2 part.
Various raw materials optimum ratio by weight is: 50 parts of Oleum sesami, 15 parts in Cera Flava, 4 parts in Vermilion powder, 4 parts of Crinis Carbonisatus, 1 part in Pericarpium Zanthoxyli, 2 parts of Calomelass, 5 parts of aluminium powders, 1 part of Succinum powder.
The present invention also provides a kind of technical scheme that solves the problems of the technologies described above following: a kind of change dressings method for preparing of external-applied ointment of anal fistula after operation wound surface that is used for comprises the following steps:
Step 1, Oleum sesami is placed in the pot of heating, little fire heating adds Crinis Carbonisatus after the boiling;
Step 2, etc. put into pot to Pericarpium Zanthoxyli after the Crinis Carbonisatus flavescence, after one minute Pericarpium Zanthoxyli, Crinis Carbonisatus are pulled out, again Cera Flava is put into pot, stop heating this moment;
Step 3, etc. after the Cera Flava dissolving, material in the pot is filtered in the container, stir after after the cooling aluminium powder, Succinum powder, Vermilion powder being put into and get final product;
Further, also can the ointment of processing according to above-mentioned steps be added an amount of vaseline, process Emulsion with common process.
In technique scheme, the various raw materials in the compositing formula have following effect:
The Calomelas main component is a calomel, and is hot, cold, poisonous, and external mainly has the effect that removing the necrotic tissue, granulation promoting, counteracting toxic substances are held back skin ulcer; The main Containing Sulfur hydrargyrum of Vermilion (HgS), hot, the temperature, poisonous of abnormal smells from the patient; Have antibacterial, antidotal function, external has the effect of granulation promoting detoxifcation; The pained tepor of its property of medicine of Crinis Carbonisatus, bitter in the mouth have the effect of hemostasia and promoting granulation; Resinous, the volatile oil of succinum master, the external hemostasia and promoting granulation; Oleum sesami and Cera Flava external have astringent therapy, hold back skin ulcer, the effect of pain relieving, granulation promoting, and the substrate of the ointment of can be used as is arranged; Pericarpium Zanthoxyli acrid in the mouth, hot in nature, externally-used pain-relieving, antipruritic, detoxifcation, antibacterial.
The present invention from the cause of disease, the pathogenesis of anal fistula, selects for use said medicine to carry out prescription according to Traditional Chinese medical theory, reuses powerful removing the necrotic tissue, granulation promoting that the metal medicine had, holds back skin ulcer, detoxifcation, analgesic effect, thereby reach the purpose that promotes wound healing.
The present invention is a kind of to be used for that the anal fistula after operation wound surface changes dressings that external-applied ointment has removing the necrotic tissue, granulation promoting, holds back skin ulcer, detoxifcation, pain relieving, germ-resistant effect, is mainly used in the anal fistula after operation wound surface and changes dressings.Being used for behind other hemorrhoid operations wound surface changes dressings certain effect is also arranged.
External-applied ointment method for preparing of the present invention is simple, and raw material is easy to get.
The present invention and tradition are changed dressings the cleaning wound surface relatively, and healing time all has shortening in various degree, and curative effect is obvious.
Anal fistula after operation wound surface of the present invention is changed dressings surplus the external-applied ointment clinical practice existing 20 year, and is in order to show effect of the present invention, existing that clinical practice situation report of the present invention is following:
Change dressings at the anal fistula after operation wound surface and promote the wound healing effect in order to observe this invention, we have carried out the clinical control experiment.Adopt random packet to use different mode of dressing change, the condition of each group is through the statistical test indifference.
1, clinical data
1.1 physical data: all case all meets " the disease diagnostic criteria of traditional Chinese medical science anorectal section " and the diagnostic criteria of national first anorectal academic conference formulation that State Administration of Traditional Chinese Medicine formulates.Wherein use the simple property of low level anal fistula 366 examples that tradition is changed dressings, high-order simple property anal fistula 119 examples, low level complexity anal fistula 273 examples, high-order complexity anal fistula 95 examples; Use the simple property of low level anal fistula 359 examples that ointment of the present invention is changed dressings, high-order simple property anal fistula 126 examples, low level complexity anal fistula 279 examples, high-order complexity anal fistula 98 examples, the condition of each group is through statistical test indifference (P＞0.05).
1.2 Therapeutic Method: treatment group: anal fistula after operation, conventional cleaning wound surface is used ointment of the present invention and is applied on the wound surface, and with an amount of absorbent cotton filling otch, every day 1 time is until wound healing.Matched group: anal fistula after operation, conventional cleaning wound surface is with oil-sand bar filling otch.All the other treatments are all used same procedure like treatment group such as infection, medicine fumigation and wash method and matched group.
1.3 observation index is observed the wound healing time.
1.4. treatment standard: the curative effect determinate standard of formulating according to " traditional Chinese medical science anorectal section disease criterion of therapeutical effect " and the anorectal academic conference of the first whole nation of State Administration of Traditional Chinese Medicine's formulation carries out efficacy evaluation.
2. therapeutic outcome:
Treatment group and matched group case load and therapeutic effect are seen table 1 and table 2 respectively:
The table 1. difference anal fistula patient example number of changing dressings
| Group | The tradition routine number of changing dressings | Use the ointment of the present invention routine number of changing dressings |
| The simple property of low level anal fistula | 366 | 359 |
| High-order simple property anal fistula | 119 | 126 |
| Low level complexity anal fistula | 273 | 279 |
| High-order complexity anal fistula | 95 | 98 |
The change dressings natural law (x ± sd) of wound healing of the different anal fistula patients of table 2.
| Group | The tradition healing natural law of changing dressings | Use the ointment of the present invention healing natural law of changing dressings |
| The simple property of low level anal fistula | 21.9±5.6 | 16.4±4.8 |
| High-order simple property anal fistula | 28.7±6.4 | 22.6±6.9 |
| Low level complexity anal fistula | 22.3±5.7 | 17.1±6.2 |
| High-order complexity anal fistula | 29.2±6.8 | 23.7±7.5 |
Visible by last table, this invention is compared with traditional dressing change, can reach to make the purpose that wound healing is fast, therapeutic effect is good property (P＜0.05) that relatively there were significant differences between each respective sets.
The specific embodiment
Embodiment 1
Get material by following prescription: Oleum sesami 500g, Cera Flava 150g, Vermilion powder 40g, Crinis Carbonisatus 40g, Pericarpium Zanthoxyli 10g, Calomelas 20g, aluminium powder 50g, Succinum powder 10g.Process through following method: Oleum sesami is placed in the pot of heating, little fire heating adds Crinis Carbonisatus after the boiling; Put into pot to Pericarpium Zanthoxyli Deng after the Crinis Carbonisatus flavescence, after one minute Pericarpium Zanthoxyli, Crinis Carbonisatus are pulled out, again Cera Flava is put into pot; Stop heating this moment, wait Cera Flava dissolving after, material in the pot is filtered in the container; Stir after after the cooling Calomelas, aluminium powder, Succinum powder, Vermilion powder being put into and get final product, place subsequent use.When anal fistula after operation is changed dressings, behind the cleaning wound surface ointment of the present invention evenly is applied on the wound surface, in right amount once a day.
Embodiment 2
Get material by following prescription: Oleum sesami 250g, Cera Flava 100g, Vermilion powder 20g, Crinis Carbonisatus 30g, Pericarpium Zanthoxyli 5g, Calomelas 10g, aluminium powder 30g, Succinum powder 10g.Through making external-applied ointment, place subsequent use with embodiment 1 identical method.Method for using is identical with embodiment 1.
Embodiment 3
Get material by following prescription: Oleum sesami 300g, Cera Flava 100g, Vermilion powder 30g, Crinis Carbonisatus 40g, Pericarpium Zanthoxyli 10g, Calomelas 10g, aluminium powder 20g, Succinum powder 10g.Through making external-applied ointment with embodiment 1 identical method.Method for using is identical with embodiment 1.
Embodiment 4
Get material by following prescription: Oleum sesami 250g, Cera Flava 100g, Vermilion powder 30g, Crinis Carbonisatus 40g, Pericarpium Zanthoxyli 10g, Calomelas 10g, aluminium powder 20g, Succinum powder 10g.Through making external-applied ointment with embodiment 1 identical method.Again ointment is added adjuvant vaseline 120g, the packing of mix homogeneously routine disinfection, it is subsequent use to make Emulsion by common process.Behind the cleaning wound surface, use this Emulsion and evenly be applied on the wound surface when anal fistula after operation is changed dressings every day, absorbent cotton filling otch.
Claims (4)
1. one kind is used for the anal fistula after operation wound surface external-applied ointment of changing dressings, and it is characterized in that: said external-applied ointment is processed by following raw material by weight ratio: Oleum sesami 50-100 part, Cera Flava 15-30 part, Vermilion powder 4-10 part, Crinis Carbonisatus 4-10 part, Pericarpium Zanthoxyli 1-2 part, Calomelas 2-5 part, aluminium powder 5-10 part, Succinum powder 1-2 part.
2. a kind of anal fistula after operation wound surface external-applied ointment of changing dressings that is used for according to claim 1, it is characterized in that: each raw material optimum ratio by weight is: 50 parts of Oleum sesami, 15 parts in Cera Flava, 4 parts in Vermilion powder, 4 parts of Crinis Carbonisatus, 1 part in Pericarpium Zanthoxyli, 2 parts of Calomelass, 5 parts of aluminium powders, 1 part of Succinum powder.
3. the change dressings method for preparing of external-applied ointment of anal fistula after operation wound surface that is used for as claimed in claim 1 is characterized in that said method for preparing comprises the following steps:
Step 1, Oleum sesami is placed in the pot of heating, little fire heating adds Crinis Carbonisatus after the boiling;
Step 2, etc. put into pot to Pericarpium Zanthoxyli after the Crinis Carbonisatus flavescence, after one minute Pericarpium Zanthoxyli, Crinis Carbonisatus are pulled out, again Cera Flava is put into pot, stop heating this moment;
Step 3, etc. after the Cera Flava dissolving, material in the pot is filtered in the container, stir after after the cooling aluminium powder, Succinum powder, Vermilion powder and Calomelas being put into and get final product;
4. the change dressings method for preparing of external-applied ointment of anal fistula after operation wound surface that is used for according to claim 3 is characterized in that: also comprise ointment is added appropriate amount of auxiliary materials, process Emulsion with common process.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010106086991A CN102078422B (en) | 2010-12-28 | 2010-12-28 | External ointment used for changing medicine for anal fistula postoperative wound surface and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010106086991A CN102078422B (en) | 2010-12-28 | 2010-12-28 | External ointment used for changing medicine for anal fistula postoperative wound surface and preparation method thereof |
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| Publication Number | Publication Date |
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| CN102078422A CN102078422A (en) | 2011-06-01 |
| CN102078422B true CN102078422B (en) | 2012-08-01 |
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| CN2010106086991A Expired - Fee Related CN102078422B (en) | 2010-12-28 | 2010-12-28 | External ointment used for changing medicine for anal fistula postoperative wound surface and preparation method thereof |
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| CN104398545A (en) * | 2014-10-30 | 2015-03-11 | 刘永强 | Traditional Chinese medicinal ointment for treating dermatopathy, and its preparation method |
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|---|---|---|---|---|
| CN1113152A (en) * | 1994-03-29 | 1995-12-13 | 卢贤元 | Medicinal preparation for treatment of fistula |
| CN1410121A (en) * | 2002-11-27 | 2003-04-16 | 荣文舟 | Medicine for treating archosyrinx and its preparation method |
| CN1555860A (en) * | 2004-01-06 | 2004-12-22 | 马书仁 | Medicine for treating hemorrhoids and fistulas |
| CN1931322A (en) * | 2005-09-15 | 2007-03-21 | 闫国鲁 | Anal fistula treating Chinese medicine |
-
2010
- 2010-12-28 CN CN2010106086991A patent/CN102078422B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1113152A (en) * | 1994-03-29 | 1995-12-13 | 卢贤元 | Medicinal preparation for treatment of fistula |
| CN1410121A (en) * | 2002-11-27 | 2003-04-16 | 荣文舟 | Medicine for treating archosyrinx and its preparation method |
| CN1555860A (en) * | 2004-01-06 | 2004-12-22 | 马书仁 | Medicine for treating hemorrhoids and fistulas |
| CN1931322A (en) * | 2005-09-15 | 2007-03-21 | 闫国鲁 | Anal fistula treating Chinese medicine |
Non-Patent Citations (5)
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| 林娜等.解毒生肌膏Ⅱ号的制备及质量控制.《辽宁中医杂志》.2004,第5卷(第05期), * |
| 柯敏辉等.中药油膏外用促进肛瘘术后创面愈合的研究进展.《中医外治杂志》.2008,第17卷(第02期), * |
| 许伟等.中西医结合治疗手部创面.《中国中医骨伤科》.1999,第7卷(第03期), * |
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| 陈映标.挂线加中药治疗肛瘘250例疗效观察.《新中医》.2005,第37卷(第04期), * |
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