CN102049090B - Moxibustion patch and preparation method thereof - Google Patents
Moxibustion patch and preparation method thereof Download PDFInfo
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- CN102049090B CN102049090B CN2010105948534A CN201010594853A CN102049090B CN 102049090 B CN102049090 B CN 102049090B CN 2010105948534 A CN2010105948534 A CN 2010105948534A CN 201010594853 A CN201010594853 A CN 201010594853A CN 102049090 B CN102049090 B CN 102049090B
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- quintessence oil
- film forming
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- 238000002360 preparation method Methods 0.000 title abstract description 5
- 229920000642 polymer Polymers 0.000 claims abstract description 24
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 15
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 15
- 235000006708 antioxidants Nutrition 0.000 claims abstract description 15
- 239000000839 emulsion Substances 0.000 claims abstract description 13
- 239000011248 coating agent Substances 0.000 claims abstract description 7
- 238000000576 coating method Methods 0.000 claims abstract description 7
- 239000000758 substrate Substances 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 239000003921 oil Substances 0.000 claims description 63
- 239000000123 paper Substances 0.000 claims description 18
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 15
- 239000002585 base Substances 0.000 claims description 13
- 239000000463 material Substances 0.000 claims description 13
- 239000004034 viscosity adjusting agent Substances 0.000 claims description 13
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims description 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- 239000012528 membrane Substances 0.000 claims description 9
- 238000005520 cutting process Methods 0.000 claims description 7
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 6
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 6
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 claims description 6
- 239000003431 cross linking reagent Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 239000000080 wetting agent Substances 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 4
- 229920001661 Chitosan Polymers 0.000 claims description 4
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 claims description 4
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 4
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 4
- BHKAWXZKFKVZLK-UHFFFAOYSA-N 2,3-ditert-butyl-6-methylphenol Chemical compound CC1=CC=C(C(C)(C)C)C(C(C)(C)C)=C1O BHKAWXZKFKVZLK-UHFFFAOYSA-N 0.000 claims description 3
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims description 3
- 239000005995 Aluminium silicate Substances 0.000 claims description 3
- 239000004255 Butylated hydroxyanisole Substances 0.000 claims description 3
- 229930003427 Vitamin E Natural products 0.000 claims description 3
- 229940072056 alginate Drugs 0.000 claims description 3
- 235000010443 alginic acid Nutrition 0.000 claims description 3
- 229920000615 alginic acid Polymers 0.000 claims description 3
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 3
- 229910021502 aluminium hydroxide Inorganic materials 0.000 claims description 3
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 3
- 235000012211 aluminium silicate Nutrition 0.000 claims description 3
- 235000019282 butylated hydroxyanisole Nutrition 0.000 claims description 3
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 claims description 3
- 229940043253 butylated hydroxyanisole Drugs 0.000 claims description 3
- 239000006185 dispersion Substances 0.000 claims description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 3
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 3
- 238000010030 laminating Methods 0.000 claims description 3
- 239000000171 lavandula angustifolia l. flower oil Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 229920000058 polyacrylate Polymers 0.000 claims description 3
- 239000000473 propyl gallate Substances 0.000 claims description 3
- 235000010388 propyl gallate Nutrition 0.000 claims description 3
- 229940075579 propyl gallate Drugs 0.000 claims description 3
- 235000019165 vitamin E Nutrition 0.000 claims description 3
- 229940046009 vitamin E Drugs 0.000 claims description 3
- 239000011709 vitamin E Substances 0.000 claims description 3
- LUEWUZLMQUOBSB-FSKGGBMCSA-N (2s,3s,4s,5s,6r)-2-[(2r,3s,4r,5r,6s)-6-[(2r,3s,4r,5s,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5s,6r)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H](O[C@@H](OC3[C@H](O[C@@H](O)[C@@H](O)[C@H]3O)CO)[C@@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O LUEWUZLMQUOBSB-FSKGGBMCSA-N 0.000 claims description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 2
- 235000001206 Amorphophallus rivieri Nutrition 0.000 claims description 2
- 244000247812 Amorphophallus rivieri Species 0.000 claims description 2
- 235000010894 Artemisia argyi Nutrition 0.000 claims description 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 2
- 229920002581 Glucomannan Polymers 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- 229920002752 Konjac Polymers 0.000 claims description 2
- 244000178231 Rosmarinus officinalis Species 0.000 claims description 2
- BWZOPYPOZJBVLQ-UHFFFAOYSA-K aluminium glycinate Chemical compound O[Al+]O.NCC([O-])=O BWZOPYPOZJBVLQ-UHFFFAOYSA-K 0.000 claims description 2
- 244000030166 artemisia Species 0.000 claims description 2
- 239000001110 calcium chloride Substances 0.000 claims description 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 2
- 239000000969 carrier Substances 0.000 claims description 2
- 229940015826 dihydroxyaluminum aminoacetate Drugs 0.000 claims description 2
- 229940046240 glucomannan Drugs 0.000 claims description 2
- 229940119170 jojoba wax Drugs 0.000 claims description 2
- 239000008633 juniper tar Substances 0.000 claims description 2
- 239000000252 konjac Substances 0.000 claims description 2
- 235000010485 konjac Nutrition 0.000 claims description 2
- 229940088417 precipitated calcium carbonate Drugs 0.000 claims description 2
- 210000000582 semen Anatomy 0.000 claims description 2
- 239000000377 silicon dioxide Substances 0.000 claims description 2
- 235000012239 silicon dioxide Nutrition 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000000661 sodium alginate Substances 0.000 claims description 2
- 235000010413 sodium alginate Nutrition 0.000 claims description 2
- 229940005550 sodium alginate Drugs 0.000 claims description 2
- 239000000341 volatile oil Substances 0.000 abstract description 9
- 238000001467 acupuncture Methods 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 3
- 238000002156 mixing Methods 0.000 abstract description 2
- 238000013268 sustained release Methods 0.000 abstract 4
- 239000012730 sustained-release form Substances 0.000 abstract 4
- 238000010438 heat treatment Methods 0.000 abstract 3
- 239000002002 slurry Substances 0.000 abstract 2
- 238000001035 drying Methods 0.000 abstract 1
- 238000007493 shaping process Methods 0.000 abstract 1
- 239000004745 nonwoven fabric Substances 0.000 description 8
- 239000000243 solution Substances 0.000 description 4
- 238000005303 weighing Methods 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000011259 mixed solution Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000010802 sludge Substances 0.000 description 3
- 239000001038 titanium pigment Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000004089 microcirculation Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
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Images
Abstract
The invention relates to a moxibustion patch and a preparation method thereof. The moxibustion patch is characterized by comprising a heating body and an essential oil sustained-release film layer, wherein one surface of the heating body is a breather layer, the other surface of the heating body is jointed with the essential oil sustained-release film layer, the essential oil sustained-release film layer is formed by coating thick slurry with the viscosity of 80000-100000 centipoises on the surface of a substrate and drying till curing, shaping and forming a film, the thick slurry comprises one of polymer emulsion capable of forming the film or polymer solution capable of forming the film, essential oil, an essential oil carrier, an antioxidant and a viscosity regulator and is formed by mixing the components, and the parts by weight of all raw material components are as follows: the polymer emulsion accounts for 73-89.3 parts, the essential oil accounts for 0.2-3 parts, the essential oil carrier accounts for 9-20 parts, the anti-oxidant accounts for 0.01-0.5 part, and the viscosity regulator accounts for 0-3.9 parts. The moxibustion patch is attached to the surface of skin or an acupuncture point, has a quantitative sustained-release effect, and can ensure that the health care effect of the essential oil is brought to full play; and furthermore, the use is convenient, and the moxibustion patch does not pollute clothes.
Description
Technical field
The present invention relates to a kind of moxibustion patch and preparation method thereof with health-care efficacy.
Background technology
Self has regulating action to human body quintessence oil, but quintessence oil directly is coated on skin surface, and consumption is restive, and bioavailability is low, is difficult to give full play to effect.Just there is pair body local in China with baking, the moxibustion therapy of hot compress to scheme to get rid of illness and to be healthy and strong from ancient times.Chinese patent ZL200610019420.X disclose a kind of heat pack making method and with the connected structure of medicament.This medicament is solid-state when storage, meets thermosol when using and is liquid state, though the promotion osmosis is arranged, certain flowability is arranged, and has the defective of pollution clothes.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of moxibustion patch and preparation method thereof.This moxibustion patch has quantitative slow releasing function, can make quintessence oil give full play to its health-care efficacy, and easy to use, can pollution clothes.
For solving the technical problem that the present invention proposes, the technical scheme that is adopted is:
A kind of moxibustion patch; It is characterized in that: comprise heater and quintessence oil slow release rete; Heater simultaneously is ventilative aspect; Another side and quintessence oil release membranes laminating close; Said quintessence oil slow release rete is that the stiff slip of 80000～100000 centipoises is coated on substrate surface and dries by the fire to the solidifying and setting film forming and get by viscosity; Obtain but described stiff slip comprises that but a kind of, quintessence oil, quintessence oil carrier, antioxidant and viscosity modifier in film forming polymer emulsion or the film forming polymer solution mixes, the weight portion of each raw material components is: 73～89.3 parts of polymer emulsions, 0.2～3 part of quintessence oil, 9～20 parts in quintessence oil carrier, 0.01～0.5 part of antioxidant, 0～3.9 part of viscosity modifier.
Pressing such scheme, is that 40～50% polyacrylate dispersion or commercially available mass concentration (g/L) are a kind of in 40～50% the benzene emulsion but described film forming polymer emulsion is a commercially available mass concentration (g/L); But the mass concentration of described film forming polymer solution (g/L) is 1～10%, but described film forming polymer is a kind of in sodium polyacrylate, polyvinyl alcohol, chitosan, sodium alginate, the Konjac glucomannan.
Press such scheme, described base material is cloth, non-woven fabrics or paper.
Press such scheme, described stiff slip also can add wetting agent, and described wetting agent is a glycerol, and the weight portion of said wetting agent is 1-5 part.
Press such scheme, described stiff slip also can add cross-linking agent, and described cross-linking agent is a kind of in aluminium hydroxide, dihydroxyaluminum aminoacetate, calcium chloride, the aluminum chloride, and the weight portion of said cross-linking agent is 0.2-2 part.
Press such scheme, described quintessence oil is one or more in Oleum Folium Artemisiae Argyi, Semen Myristicae oil, Oleum Cinnamomi, Essential lavender oil, Chinese mugwort sodium Oleum sesami, oil of Rhizoma Zingiberis Recens, cade oil, Jojoba oil, the oil of rosemary.
Press such scheme, described quintessence oil carrier is one or more in silicon dioxide, alumina support, Kaolin, the precipitated calcium carbonate.
Press such scheme, described antioxidant is one or more of vitamin E, di-tert-butyl hydroxy-methylbenzene, Butylated hydroxyanisole, propyl gallate.
Press such scheme, described viscosity modifier is one or more in the FS-20C viscosity modifier produced of Dandong fixed star fine chemistry industry company, CMC, the alginate propylene glycol.
Press such scheme, said stiff slip also can add colorant, and described colorant is a white titanium pigment.
Press such scheme, the both sides of said heater or pressure sensitive adhesive is set, and configuration release paper all around.
The method for preparing of above-mentioned moxibustion patch may further comprise the steps:
(1) by weight; In 9～20 parts of quintessence oil carriers, add 0.2～3 part of quintessence oil, be about to quintessence oil in advance appendix on carrier mass, add a kind of and 0.01～0.5 part of antioxidant in 73～89.3 parts of polymer emulsions or the polymer solution again; Fully mix; Add 0～3.9 part of viscosity modifier, regulate viscosity to 80000～100000 centipoises of feed liquid, obtain the stiff slip;
(2) the stiff slip of step (1) being prepared is coated the one side of base material; Hot blast dries by the fire to solidifying and setting film forming (can keep not rheology of profile), obtains the quintessence oil release membranes, in the another side pressure-sensitive adhesive coating of base material; Cover release paper then, obtain quintessence oil slow release diaphragm according to required specification cross cutting;
(3) the quintessence oil slow release diaphragm that step (2) is obtained is peelled off release paper, is attached at and obtains the moxibustion patch on the heater.
During use,, be attached at skin surface or acupuncture point and can bring into play its adjusting health care the release paper that above-mentioned moxibustion patch is peeled the heater both sides off or is provided with all around.
Beneficial effect of the present invention: the present invention is a film former with the high molecular polymer, adopts suitable carrier that quintessence oil is processed quintessence oil slow release diaphragm, and then through cross cutting, fits in heater surface composition moxibustion patch.This moxibustion patch can heat promote plants essential oil to act on human body through skin; And based on quintessence oil to the cooperative effect that the biochemical action of human body produces with certain warm physical effect, reach dredging the meridian, inrigorating qi and promoting blood circulation; Microcirculation improvement, the purpose of recovery health vigor.Simultaneously, this moxibustion patch is prepared into the release-controlled film that can quantitatively discharge active component with quintessence oil, can avoid the volatilizing loss of quintessence oil in process of production, and quintessence oil is quantitatively relatively accurate; Because can making quintessence oil give full play to it, quantitative slow releasing function regulates health-care efficacy in use; Easy to use, be difficult for pollution clothes.
Description of drawings
Fig. 1 is the moxibustion patch structural representation of an embodiment.
The specific embodiment
Through embodiment summary of the invention of the present invention is described further below.
A kind of moxibustion patch; Comprise heater 1 and quintessence oil slow release rete 4, the one side of heater is ventilative aspect, and another side and quintessence oil release membranes laminating close; Said quintessence oil release membranes is that the stiff slip of 80000～100000 centipoises is coated on substrate surface and dries by the fire to the solidifying and setting film forming and get by viscosity;, described stiff slip obtains the both sides of said heater or pressure sensitive adhesive 2 is set, and configuration release paper 3 but comprising that but a kind of, quintessence oil, quintessence oil carrier, antioxidant and viscosity modifier in film forming polymer emulsion or the film forming polymer solution mixes all around; As the adhesive portion of moxibustion patch, embodiment 1-3 is respectively the concrete method for preparing of moxibustion patch.
Embodiment 1
By weight; Take by weighing 15 parts of aerosils and 3 parts of Oleum Folium Artemisiae Argyis, mix homogeneously adds mass concentration (g/L) and is 81 parts of 40% polyacrylate dispersions; Add 0.01 part of antioxidant vitamin E then; Abundant dispersing and mixing, adding FS-20C viscosity modifier that 1 part of Dandong fixed star fine chemistry industry company produces again, to be thickened to viscosity of sludge be 100,000 centipoises, obtains the stiff slip;
Above-mentioned stiff slip is coated the one side of non-woven fabrics base material; The about 160g/m2 of coating weight, hot blast dries by the fire to the solidifying and setting film forming under about 60 ℃ condition, obtains the quintessence oil release membranes; Another side at non-woven fabrics base material applies hot-fusible pressure-sensitive adhesive then; Cover release paper again, cross cutting is in blocks, obtains quintessence oil slow release diaphragm;
Quintessence oil slow release diaphragm is removed release paper, and fitting with heater then promptly obtains the moxibustion patch.
During use, above-mentioned moxibustion patch is removed heater both sides or release paper all around, be attached at skin surface or acupuncture point then and can bring into play its adjusting health care, reach dredging the meridian, inrigorating qi and promoting blood circulation, microcirculation improvement, the purpose of recovery health vigor.
Embodiment 2
By weight, 1 part of 6.0 parts of weighing polyvinyl alcohol, 70 parts in water and glycerol mix; Be heated to 100 ℃ of dissolvings and obtain the mixed solution of polyvinyl alcohol, add by 19 parts of Kaolin 1 part of white titanium pigment; 1 part of prewired powder of Oleum Cinnamomi fully is uniformly dispersed; Add 0.1 part of antioxidant di-tert-butyl hydroxy-methylbenzene and 2 parts of alginate propylene glycol viscosity modifiers again, regulate viscosity of sludge to 10 ten thousand centipoises, obtain the stiff slip;
Above-mentioned stiff slip is coated the one side of non-woven fabrics base material; The about 200g/m2 of coating weight, part moisture content to solidifying and setting film forming is gone in the hot blast baking under about 60 ℃ of conditions, obtains the quintessence oil release membranes; Another side at base material applies the thermosol pressure sensitive adhesive then; Cover release paper again, cross cutting is in blocks, obtains quintessence oil slow release diaphragm;
Quintessence oil slow release diaphragm is removed release paper, then with the superimposed moxibustion patch that obtains of heater.
Embodiment 3
By weight; Take by weighing 5 parts of 4 parts of sodium polyacrylate, 85 parts in water, 0.6 part of aluminium hydroxide and glycerol; Dissolving obtains the mixed solution of sodium polyacrylate; Adding fully is uniformly dispersed by 10 parts of precipitated calcium carbonates, 1 part of white titanium pigment, 2 parts of cade oils and 0.3 part of prewired powder of antioxidant Butylated hydroxyanisole, promptly obtains the stiff slip of viscosity 100,000 centipoises;
Above-mentioned stiff slip is coated non-woven fabrics base material; The about 200g/m2 of coating weight, part moisture content to solidifying and setting film forming is gone in the hot blast baking under about 60 ℃ of conditions, obtains the quintessence oil release membranes; Another side at non-woven fabrics base material applies the thermosol pressure sensitive adhesive then; Cover release paper again, cross cutting is in blocks, obtains quintessence oil slow release diaphragm;
Quintessence oil slow release diaphragm is removed release paper, and fitting with heater then promptly obtains the moxibustion patch.
Embodiment 4
By weight; Take by weighing 3.3 parts of chitosans, 2 parts of acetic acid, 4 parts of 81 parts in water and glycerol; Dissolving obtains the mixed solution of chitosan; Adding fully is uniformly dispersed by 9 parts of alumina supports, 0.2 part of Essential lavender oil and 0.5 part of prewired powder of antioxidant propyl gallate, obtains the stiff slip of about 90,000 centipoises of viscosity of sludge;
Above-mentioned stiff slip is coated non-woven fabrics base material; The about 200g/m2 of coating weight, part moisture content to solidifying and setting film forming is gone in the hot blast baking under about 60 ℃ of conditions, obtains the quintessence oil release membranes; Another side at non-woven fabrics base material applies the thermosol pressure sensitive adhesive then; Cover release paper again, cross cutting is in blocks, obtains quintessence oil slow release diaphragm;
Quintessence oil slow release diaphragm is removed release paper, and fitting with heater then promptly obtains the moxibustion patch.
Claims (10)
1. moxibustion patch; It is characterized in that: comprise heater and quintessence oil slow release rete; Heater simultaneously is ventilative aspect; Another side and quintessence oil release membranes laminating close; Said quintessence oil slow release rete is that the stiff slip of 80000～100000 centipoises is coated on substrate surface and dries by the fire to the solidifying and setting film forming and get by viscosity; But but described stiff slip mix by film forming polymer emulsion or film forming polymer solution, quintessence oil, quintessence oil carrier, antioxidant and viscosity modifier and obtain, the weight portion of each raw material components is: but but 73～89.3 parts of film forming polymer emulsion or film forming polymer solution, 0.2～3 part of quintessence oil, 9～20 parts in quintessence oil carrier, 0.01～0.5 part of antioxidant, 0～3.9 part of viscosity modifier.
2. moxibustion patch according to claim 1 is characterized in that: but described film forming polymer emulsion is commercially available mass concentration is that 40～50% polyacrylate dispersion or commercially available mass concentration are a kind of in 40～50% the benzene emulsion; But the mass concentration of described film forming polymer solution is 1～10%, but but the film forming polymer in the said film forming polymer solution is a kind of in sodium polyacrylate, polyvinyl alcohol, chitosan, sodium alginate, the Konjac glucomannan.
3. moxibustion patch according to claim 1 is characterized in that: described stiff slip also adds wetting agent, and described wetting agent is a glycerol, and the weight portion of said wetting agent is 1～5 part.
4. moxibustion patch according to claim 1 is characterized in that: described stiff slip also adds cross-linking agent, and described cross-linking agent is a kind of in aluminium hydroxide, dihydroxyaluminum aminoacetate, calcium chloride, the aluminum chloride, and the weight portion of said cross-linking agent is 0.2～2 part.
5. moxibustion patch according to claim 1 is characterized in that: described quintessence oil is one or more in Oleum Folium Artemisiae Argyi, Semen Myristicae oil, Oleum Cinnamomi, Essential lavender oil, Chinese mugwort sodium Oleum sesami, oil of Rhizoma Zingiberis Recens, cade oil, Jojoba oil, the oil of rosemary.
6. moxibustion patch according to claim 1 is characterized in that: described quintessence oil carrier is one or more in silicon dioxide, alumina support, Kaolin, the precipitated calcium carbonate.
7. moxibustion patch according to claim 1 is characterized in that: described antioxidant is one or more of vitamin E, di-tert-butyl hydroxy-methylbenzene, Butylated hydroxyanisole, propyl gallate.
8. moxibustion patch according to claim 1 is characterized in that: described viscosity modifier is one or more in the FS-20C viscosity modifier produced of CMC, alginate propylene glycol, Dandong fixed star fine chemistry industry company.
9. moxibustion patch according to claim 1 is characterized in that: the both sides of said heater or pressure sensitive adhesive is set all around, and configuration release paper.
10. the method for preparing of moxibustion patch according to claim 1 is characterized in that: may further comprise the steps:
(1) by weight; In 9～20 parts of quintessence oil carriers, add 0.2～3 part of quintessence oil; But but add 73～89.3 parts of film forming polymer emulsions or film forming polymer solution and 0.01～0.5 part of antioxidant again, fully mix, add 0～3.9 part of viscosity modifier; Regulate viscosity to 80000～100000 centipoises of feed liquid, obtain the stiff slip;
(2) the stiff slip of step (1) being prepared is coated the one side of base material, and hot blast dries by the fire to the solidifying and setting film forming, obtains quintessence oil slow release rete, and the another side pressure-sensitive adhesive coating at base material covers release paper then, and cross cutting obtains quintessence oil slow release diaphragm;
(3) the quintessence oil slow release diaphragm that step (2) is obtained is peelled off release paper, is attached at and obtains the moxibustion patch on the heater.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102846426B (en) * | 2011-06-30 | 2015-10-28 | 李慧娟 | Heating paste containing Folium Artemisiae Argyi active component |
| CN102416159A (en) * | 2011-12-13 | 2012-04-18 | 成都默森医药开发有限公司 | Chinese medicinal composition for treating rheumatic ostealgia |
| CN102860927B (en) * | 2012-10-12 | 2014-01-15 | 金红叶纸业集团有限公司 | Emulsion composition and wet tissue utilizing same |
| CN104042661B (en) * | 2014-06-23 | 2017-08-01 | 葛月宾 | A kind of active component detection method in Blumea oil transdermal patch, preparation method and patch |
| CN104815272A (en) * | 2015-05-26 | 2015-08-05 | 青岛海之星生物科技有限公司 | Traditional Chinese medicine plaster for treating stress incontinence and preparation method of traditional Chinese medicine plaster |
| CN108946212B (en) * | 2018-05-31 | 2020-07-28 | 重庆凯丰医疗器械有限公司 | TDP moxibustion plaster cleaning method for powder filling |
| CN108815140A (en) * | 2018-07-30 | 2018-11-16 | 合肥仙之峰农业科技有限公司 | A kind of retreat stickers of long-acting slow cooling |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1281702A (en) * | 1999-07-22 | 2001-01-31 | 株式会社花工房三皇 | Powder and paster for promoting blood circulation and their-matched products |
| CN1446111A (en) * | 2000-04-04 | 2003-10-01 | Cns有限公司 | Microencapsulated fragrances and methods of coating microcapsules |
| CN1864653A (en) * | 2006-06-20 | 2006-11-22 | 傅金龙 | An exothermic drug plaster |
| CN201564664U (en) * | 2009-04-14 | 2010-09-01 | 王凌峰 | Medicine navel pressing paste |
-
2010
- 2010-12-20 CN CN2010105948534A patent/CN102049090B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1281702A (en) * | 1999-07-22 | 2001-01-31 | 株式会社花工房三皇 | Powder and paster for promoting blood circulation and their-matched products |
| CN1446111A (en) * | 2000-04-04 | 2003-10-01 | Cns有限公司 | Microencapsulated fragrances and methods of coating microcapsules |
| CN1864653A (en) * | 2006-06-20 | 2006-11-22 | 傅金龙 | An exothermic drug plaster |
| CN201564664U (en) * | 2009-04-14 | 2010-09-01 | 王凌峰 | Medicine navel pressing paste |
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Application publication date: 20110511 Assignee: Wuhan Guo Yan Technology Development Co.,Ltd. Assignor: Fu Jinlong Contract record no.: 2014420000169 Denomination of invention: Moxibustion patch and preparation method thereof Granted publication date: 20121121 License type: Exclusive License Record date: 20140821 |
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Inventor after: Zhao Xuelin Inventor after: Tian Hui Inventor before: Zhao Xuelin |
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Address after: 430223 Wuhan County, Jiangxia Road, Jiangxia District, Hubei 1, Wuhan Pharmaceutical Industry Park National moxibustion science and Technology Development Co., Ltd. Patentee after: Fu Jinlong Address before: 430223 Wuhan County, Jiangxia Road, Jiangxia District, Hubei 1, Wuhan Pharmaceutical Industry Park National moxibustion science and Technology Development Co., Ltd. Patentee before: Fu Jinlong |
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Effective date of registration: 20230222 Address after: 430299 No. 1, Miaoshan Avenue, Jiangxia, Wuhan, Hubei Province (Wuhan Pharmaceutical Industrial Park) Patentee after: WUHAN GUOJIU TECHNOLOGY DEVELOPMENT CO.,LTD. Address before: 430223 Wuhan Pharmaceutical Industrial Park guomoxibustion Technology Development Co., Ltd., No. 1, Jiangxia Avenue, Jiangxia District, Wuhan City, Hubei Province Patentee before: Fu Jinlong |