CN102018623B - Blow molded medical bag and preparation method thereof - Google Patents
Blow molded medical bag and preparation method thereof Download PDFInfo
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- CN102018623B CN102018623B CN200910187574.3A CN200910187574A CN102018623B CN 102018623 B CN102018623 B CN 102018623B CN 200910187574 A CN200910187574 A CN 200910187574A CN 102018623 B CN102018623 B CN 102018623B
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- bag
- propylene
- copolymer
- butylene
- ethylene
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- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 229920001577 copolymer Polymers 0.000 claims abstract description 36
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 claims abstract description 35
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 claims abstract description 35
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims abstract description 25
- 239000005977 Ethylene Substances 0.000 claims abstract description 25
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 claims abstract description 25
- 239000002994 raw material Substances 0.000 claims abstract description 21
- 239000000463 material Substances 0.000 claims abstract description 19
- -1 ethylene, propylene Chemical group 0.000 claims abstract description 15
- 239000004743 Polypropylene Substances 0.000 claims abstract description 10
- 229920001155 polypropylene Polymers 0.000 claims abstract description 10
- 238000000465 moulding Methods 0.000 claims abstract description 6
- 238000001746 injection moulding Methods 0.000 claims abstract description 3
- 229920005606 polypropylene copolymer Polymers 0.000 claims abstract 3
- 239000004033 plastic Substances 0.000 claims description 24
- 229920003023 plastic Polymers 0.000 claims description 24
- 239000000047 product Substances 0.000 claims description 21
- 238000010438 heat treatment Methods 0.000 claims description 20
- 238000002347 injection Methods 0.000 claims description 20
- 239000007924 injection Substances 0.000 claims description 20
- 239000013065 commercial product Substances 0.000 claims description 10
- 238000001816 cooling Methods 0.000 claims description 10
- 238000000071 blow moulding Methods 0.000 claims description 7
- 238000007664 blowing Methods 0.000 claims description 7
- 229920000426 Microplastic Polymers 0.000 claims description 5
- 230000005540 biological transmission Effects 0.000 claims description 5
- 230000000694 effects Effects 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 230000000750 progressive effect Effects 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 5
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 14
- 238000001802 infusion Methods 0.000 abstract description 5
- 239000000203 mixture Substances 0.000 abstract description 5
- 238000003466 welding Methods 0.000 abstract description 5
- 230000007812 deficiency Effects 0.000 abstract description 3
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 1
- 238000012797 qualification Methods 0.000 abstract 1
- 238000005469 granulation Methods 0.000 description 3
- 230000003179 granulation Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Abstract
The invention discloses a blow molded medical bag and a preparation method thereof. The invention is characterized in that the medical bag is manufactured by one-step molding of a bag body and an interface at the top of the bag body, and is made of a mixture consisting of a copolymer of medical ethylene and propylene or a copolymer of medical ethylene, propylene and butylene or a copolymer of propylene, butylene and styrene and polypropylene; and the preparation method comprises the following steps: performing injection molding on a bag base; and obtaining the blow molded medical bag by biaxial tension. The invention has the characteristics of overcoming the deficiency of a non-PVC material infusion bag so as to lead the raw material of the medical bag to be independent from imported non-PVC films, realizing diversification of manufacturing raw materials, being capable of molding the bag body and the interface by one step so as to avoid the problems of liquid leakage and pollution caused by secondary welding of a non-PVC soft bag and an interface, and having the advantages of high transparency and flexibility, low cost, high finished product qualification rate and suitability for industrialized production compared with the existing medical bag.
Description
Technical field
The present invention relates to a kind of plastic packing product and preparation method thereof, particularly relate to a kind of non-PVC film that can replace and manufacture material of the blow molded medical bag of transfusion bag and preparation method thereof, belong to A61J1/10 (2006.01) the I technical field in IPC International Patent Classification (IPC).
Background technology
At present, the infusion products majority of the medical plastic packaging that hospital is used is the soft bag of being made up of non-PVC film, with this soft transfusion bag of being made by non-PVC film, have manufacture easy, production floor space is little, lightweight, withstand voltage, convenient transportation, pollutes the advantages such as few when infusion and infusion fast, and replacing rapidly vial or polypropylene hard plastic bottle becomes the main flow packaging of transfusion from now on.But the film material overwhelming majority that current of home make non-PVC-soft-bag uses is all from the import of Cryovac company, price is very expensive, and production cost is high, also has manufacturer production though domestic, but the membrane material amount of producing does not pass a test, its finished product leakage rate is high, poor toughness, easily broken.Therefore, Cryovac company monopolizing market and the price of Chinese non-PVC film material, domestic non-PVC soft bag transfusion manufacturing firm cost can be in any more.Meanwhile, in bag process, bag perimeter is comprehensive welding, and the tailing of generation can not be recycled again, but also will manufacture separately interface, and interface there will be micro-seepage or easily caused weldering while welding with bag film, thereby affects non-PVC-soft-bag quality.In addition infusion products is introduced interface and is welded in manufacture process, also can increase the pollution probability to medicine.
Publication number is that the Chinese utility model patent of CN201139760 provides one " blow molding medical bag ", the raw material that this medical bag uses is medical grade polyethylene, medical grade polypropylene or medical grade modified polypropene, adopt hollow blow molding fabrication techniques, comprise bag, on bag, be provided with filling exit and the suspension ring of protrusion, described bag, filling exit and the suspension ring structure that is formed in one, has solved the problem that existing non-PVC material transfusion bag exists.But, this technical scheme does not further relate to the raw-material concrete composition that medical bag uses, the more one-body molded processing technology of medical bag is not carried out to detailed disclosure, retrieve verification through the applicant: about material of blow molded medical bag and preparation method thereof, do not see more concrete report at home and abroad.Therefore material of, finding out suitable blow molded medical bag and preparation method thereof still needs those skilled in the art further to make creationary research work.
Summary of the invention
The object of the invention is to solve the problems referred to above that prior art exists, by Improvement repeatedly, provide a kind of new blow molded medical bag and preparation method thereof, this blow molded medical bag is except the advantage having with existing medical bag, overcome the deficiency of non-PVC material transfusion bag, make the raw material of medical bag no longer rely on external non-PVC film, realize the diversification of making raw material, simultaneously due to by bag and the disposable making molding of interface, welding causes again leakage and the pollution problem of non-PVC-soft-bag and interface are avoided, also have more transparent than existing medical bag, more pliable and tougher, cost is low, the high feature with more adapting to suitability for industrialized production of product qualified rate.
The technical scheme that the present invention provides is: this blow molded medical bag, by bag, the disposable making molding of interface on bag top, the material that is characterized in this medical bag is copolymer or medicinal ethylene and the propylene of a kind of pharmaceutical grade ethylene and propylene, the copolymer of butylene or propylene and butylene, cinnamic copolymer mixes formation with another kind of polypropylene, the wherein copolymer of pharmaceutical grade ethylene and propylene or medicinal ethylene and propylene, the copolymer of butylene or propylene and butylene, the percetage by weight of cinnamic copolymer is 10～30%, polyacrylic percetage by weight is 70～90%.
The preparation method of this blow molded medical bag that the present invention provides, is characterized in being made up of following steps:
(1) injection moulding bag base:
On injection machine, install a bag mold tool, start barrel heating, operating temperature is 200 DEG C to 240 DEG C, then in the hopper of injection machine, fill it up with pharmaceutical grade plastic raw materials, this raw material is by copolymer or medicinal ethylene and the propylene of a kind of pharmaceutical grade ethylene and propylene, the copolymer of butylene or propylene and butylene, cinnamic copolymer and another kind of polypropylene form, the wherein copolymer of pharmaceutical grade ethylene and propylene or medicinal ethylene and propylene, the copolymer of butylene or propylene and butylene, the percetage by weight of cinnamic copolymer is 10～30%, polyacrylic percetage by weight is 70～90%, after heating-up temperature reaches, start injection machine, plastic pellet is through the mixing effect of injecting machine material tube inner screw, by the solid-state molten condition that is converted into, under barrel inner screw applied pressure, by the plastic injection progressive die tool of molten condition, after cooling, become the bag base of solid, the demoulding obtains a bag base product,
(2) biaxial tension blowing:
Putting bag base into reason base machine lines up it in an orderly manner, through the transmission of upper base system, the heating system that enters blow moulding machine heats, heating system is revolving, and bag base is heated to 110 DEG C～150 DEG C, and the bag base heating enters blow mold, in blow mold, the longitudinal stretching of drawn bar and laterally blowing, then through cooling, become blow molded medical bag.
Compared with prior art, the invention has the beneficial effects as follows: except the advantage having with existing medical bag, overcome the deficiency of non-PVC material transfusion bag, make the raw material of medical bag no longer rely on external non-PVC film, realize the diversification of making raw material, simultaneously due to by bag and the disposable making molding of interface, avoid the welding again leakage and the pollution problem that cause of non-PVC-soft-bag and interface, also had than existing medical bag is more transparent, more pliable and tougher, cost is low, product qualified rate is high and more adapt to the feature of suitability for industrialized production.
Detailed description of the invention
Embodiment 1.
First on injection machine, install a bag mold tool, start barrel heating, operating temperature is 210 DEG C, in the hopper of injection machine, fill it up with pharmaceutical grade plastic raw materials, this raw material is made up of copolymer and the another kind of polypropylene of a kind of pharmaceutical grade ethylene and propylene, wherein the percetage by weight of the copolymer of pharmaceutical grade ethylene and propylene is 10～30%, polyacrylic percetage by weight is 70～90%, after heating-up temperature reaches, start injection machine, plastic pellet is through the mixing effect of injecting machine material tube inner screw, by the solid-state molten condition that is converted into, under barrel inner screw applied pressure, by the plastic injection progressive die tool of molten condition, after cooling, become the bag base of solid, the demoulding obtains a bag base product, bag base being put into reason base machine lines up in an orderly manner again, through the transmission of upper base system, the heating system that enters blow moulding machine heats, heating system is revolving, and bag base is heated to 120 DEG C, and the bag base heating enters blow mold, in blow mold, the longitudinal stretching of drawn bar and laterally blowing, then through cooling, become blow molded medical bag.
In the present embodiment, the pharmaceutical grade plastic raw materials of this blow molded medical bag is:
(1) DF610 (10%)+S331 (90%%), or
(2) DF810 (20%)+S331 (80%), or
(3)DF940(30％)+S331(70％)，
Mix according to the above ratio, obtain through granulator granulation.DF610, the DF810 that the present embodiment uses and DF940 are the commercial product code of the Tafmer series of products of Mitsui Co., Ltd. sale; S331 is the commercial product code of the pharmaceutical grade plastic product of private company limited of Singapore sale.
Embodiment 2.
First on injection machine, install a bag mold tool, start barrel heating, operating temperature is 220 DEG C, in the hopper of injection machine, fill it up with pharmaceutical grade plastic raw materials, this raw material is by a kind of pharmaceutical grade ethylene and propylene, the copolymer of butylene and another kind of pharmaceutical grade polypropylene form, wherein pharmaceutical grade ethylene and propylene, the percetage by weight of the copolymer of butylene is 10～30%, polyacrylic percetage by weight is 70～90%, after heating-up temperature reaches, start injection machine, plastic pellet is through the mixing effect of injecting machine material tube inner screw, by the solid-state molten condition that is converted into, under barrel inner screw applied pressure, by the plastic injection progressive die tool of molten condition, after cooling, become the bag base of solid, the demoulding obtains a bag base product, bag base being put into reason base machine lines up in an orderly manner again, through the transmission of upper base system, the heating system that enters blow moulding machine heats, heating system is revolving, and bag base is heated to 130 DEG C, and the bag base heating enters blow mold, in blow mold, the longitudinal stretching of drawn bar and laterally blowing, then through cooling, become blow molded medical bag.
In the present embodiment, the pharmaceutical grade plastic raw materials of this blow molded medical bag is:
(1) 5C30F (10%)+8650 (90%), or
(2) 3C30F (20%)+8650 (80%), or
(3)C200F(30％)+8650(70％)，
Mix according to the above ratio, obtain through granulator granulation.5C30F, the 3C30F that the present embodiment uses and C200F are the commercial product code of the pharmaceutical grade plastics package series of products of petrochemical industry company limited of Basel sale; 8650 is the commercial product code of the pharmaceutical grade plastic packet product of atropic Fei Na company sale.
Embodiment 3.
First on injection machine, install a bag mold tool, start barrel heating, operating temperature is 230 DEG C, in the hopper of injection machine, fill it up with pharmaceutical grade plastic raw materials, this raw material is by a kind of pharmaceutical grade propylene and butylene, cinnamic copolymer and another kind of pharmaceutical grade polypropylene form, wherein pharmaceutical grade propylene and butylene, the percetage by weight of cinnamic copolymer is 10～30%, the polyacrylic percetage by weight of pharmaceutical grade is 70～90%, after heating-up temperature reaches, start injection machine, plastic pellet is through the mixing effect of injecting machine material tube inner screw, by the solid-state molten condition that is converted into, under barrel inner screw applied pressure, by the plastic injection progressive die tool of molten condition, after cooling, become the bag base of solid, the demoulding obtains a bag base product, bag base being put into reason base machine lines up in an orderly manner again, through the transmission of upper base system, the heating system that enters blow moulding machine heats, heating system is revolving, and bag base is heated to 140 DEG C, and the bag base heating enters blow mold, in blow mold, the longitudinal stretching of drawn bar and laterally blowing, then through cooling, become blow molded medical bag.
In the present embodiment, the pharmaceutical grade plastic raw materials of this blow molded medical bag is:
(1) F7702 (10%)+8650 (90%), or
(2) F8802 (20%)+8650 (80%), or
(3)F5531(30％)+8650(70％)，
Mix according to the above ratio, obtain through granulator granulation.F7702, the F8802 that the present embodiment uses and F5531 are the commercial product code of the F series of products of Taiwan KAXXON company limited sale; 8650 is the commercial product code of the pharmaceutical grade plastic packet product of atropic Fei Na company sale.
Claims (2)
1. a blow molded medical bag, by bag, the disposable making molding of interface on bag top, the material that it is characterized in that this medical bag is copolymer or medicinal ethylene and the propylene of a kind of pharmaceutical grade ethylene and propylene, the copolymer of butylene or propylene and butylene, cinnamic copolymer mixes formation with another kind of polypropylene, the wherein copolymer of pharmaceutical grade ethylene and propylene or medicinal ethylene and propylene, the copolymer of butylene or propylene and butylene, the percetage by weight of cinnamic copolymer is 10～30%, polyacrylic percetage by weight is 70～90%, described as the pharmaceutical grade ethylene of medical bag material and the copolymer of propylene or medicinal ethylene and propylene, the copolymer of butylene or propylene and butylene, cinnamic copolymer and another kind of polypropylene are:
(1) 5C30F 10%+8,650 90%, or
(2)3C30F?20％?+8650?80％?；
Above-mentioned 5C30F and 3C30F are the commercial product code of the pharmaceutical grade plastics package series of products of petrochemical industry company limited of Basel sale;
The commercial product code of the 8650 above-mentioned pharmaceutical grade plastic packet products for Atuofeina Corp's sale.
2. the preparation method of blow molded medical bag claimed in claim 1, is characterized in that being made up of following steps:
(1) injection moulding bag base:
On injection machine, install a bag mold tool, start barrel heating, operating temperature is 200 DEG C to 240 DEG C, then in the hopper of injection machine, fill it up with pharmaceutical grade plastic raw materials, this raw material is by copolymer or medicinal ethylene and the propylene of a kind of pharmaceutical grade ethylene and propylene, the copolymer of butylene or propylene and butylene, cinnamic copolymer mixes formation with another kind of polypropylene, the wherein copolymer of pharmaceutical grade ethylene and propylene or medicinal ethylene and propylene, the copolymer of butylene or propylene and butylene, the percetage by weight of cinnamic copolymer is 10～30%, polyacrylic percetage by weight is 70～90%, described as the pharmaceutical grade ethylene of medical bag material and the copolymer of propylene or medicinal ethylene and propylene, the copolymer of butylene or propylene and butylene, cinnamic copolymer and another kind of polypropylene are:
(1) 5C30F 10%+8,650 90%, or
(2)3C30F?20％?+8650?80％?；
Above-mentioned 5C30F and 3C30F are the commercial product code of the pharmaceutical grade plastics package series of products of petrochemical industry company limited of Basel sale;
The commercial product code of the 8650 above-mentioned pharmaceutical grade plastic packet products for Atuofeina Corp's sale;
After heating-up temperature reaches, start injection machine, plastic pellet is through the mixing effect of injecting machine material tube inner screw, by the solid-state molten condition that is converted into, under barrel inner screw applied pressure, by the plastic injection progressive die tool of molten condition, the bag base that becomes solid after cooling, the demoulding obtains a bag base product;
(2) biaxial tension blowing:
Bag base being put into reason base machine lines up it in an orderly manner again, through the transmission of upper base system, the heating system that enters blow moulding machine heats, heating system is revolving, and bag base is heated to 110 DEG C～150 DEG C, and the bag base heating enters blow mold, in blow mold, the longitudinal stretching of drawn bar and laterally blowing, then through cooling, become blow molded medical bag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910187574.3A CN102018623B (en) | 2009-09-23 | 2009-09-23 | Blow molded medical bag and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910187574.3A CN102018623B (en) | 2009-09-23 | 2009-09-23 | Blow molded medical bag and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102018623A CN102018623A (en) | 2011-04-20 |
| CN102018623B true CN102018623B (en) | 2014-09-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200910187574.3A Active CN102018623B (en) | 2009-09-23 | 2009-09-23 | Blow molded medical bag and preparation method thereof |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104419065A (en) * | 2013-09-03 | 2015-03-18 | 辽宁九洲龙跃药业有限公司 | Polypropylene-blended soft infusion bag and preparation method thereof |
| CN104086905B (en) * | 2014-07-25 | 2017-01-18 | 雷诺丽特塑料科技（北京）有限公司 | Modified polypropylene soft bottle material, as well as preparation method and applications thereof |
| CN111714719A (en) * | 2020-05-15 | 2020-09-29 | 华仁药业股份有限公司 | Peritoneal dialysis device adopting non-welding-point |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1133169A (en) * | 1995-04-08 | 1996-10-16 | 邬春霞 | One-step moulding making process for plastic blood (liquid) bag and manufacturing equipment |
| US6004636A (en) * | 1995-09-29 | 1999-12-21 | Fresenius Ag | Medical bag |
| CN1778541A (en) * | 2004-11-26 | 2006-05-31 | 上海紫泉饮料工业有限公司 | Production of modified and light PET thermal-loading polyester bottles |
| CN101152761A (en) * | 2006-09-26 | 2008-04-02 | 汪祥建 | Full-automatic rotary bottle blow-moulding machine |
| CN101229097A (en) * | 2008-01-14 | 2008-07-30 | 沈阳沃特药用包材科技有限公司 | Blow molding medical bag and preparing method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101234130B1 (en) * | 2004-11-29 | 2013-02-19 | 스미또모 가가꾸 가부시끼가이샤 | Polypropylene film and layered product thereof |
-
2009
- 2009-09-23 CN CN200910187574.3A patent/CN102018623B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1133169A (en) * | 1995-04-08 | 1996-10-16 | 邬春霞 | One-step moulding making process for plastic blood (liquid) bag and manufacturing equipment |
| US6004636A (en) * | 1995-09-29 | 1999-12-21 | Fresenius Ag | Medical bag |
| CN1778541A (en) * | 2004-11-26 | 2006-05-31 | 上海紫泉饮料工业有限公司 | Production of modified and light PET thermal-loading polyester bottles |
| CN101152761A (en) * | 2006-09-26 | 2008-04-02 | 汪祥建 | Full-automatic rotary bottle blow-moulding machine |
| CN101229097A (en) * | 2008-01-14 | 2008-07-30 | 沈阳沃特药用包材科技有限公司 | Blow molding medical bag and preparing method thereof |
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| CN102018623A (en) | 2011-04-20 |
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Denomination of invention: Blow molded medical bag and preparation method thereof Effective date of registration: 20150423 Granted publication date: 20140903 Pledgee: Shengjing bank Benxi branch of Limited by Share Ltd Pledgor: Liaoning N.C. Dragon Pharmaceutical Co., Ltd. Registration number: 2015210000004 |
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Denomination of invention: Blow molded medical bag and preparation method thereof Effective date of registration: 20160506 Granted publication date: 20140903 Pledgee: Shengjing bank Benxi branch of Limited by Share Ltd Pledgor: Liaoning N.C. Dragon Pharmaceutical Co., Ltd. Registration number: 2016210000008 |
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Date of cancellation: 20170425 Granted publication date: 20140903 Pledgee: Shengjing bank Benxi branch of Limited by Share Ltd Pledgor: Liaoning N.C. Dragon Pharmaceutical Co., Ltd. Registration number: 2016210000008 |
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Denomination of invention: Blow molded medical bag and preparation method thereof Effective date of registration: 20170426 Granted publication date: 20140903 Pledgee: Shengjing bank Limited by Share Ltd Benxi Pingshan Branch Pledgor: Liaoning N.C. Dragon Pharmaceutical Co., Ltd. Registration number: 2017210000011 |