CN102006888A - 通过去除自身抗体来治疗血栓闭塞性脉管炎 - Google Patents

通过去除自身抗体来治疗血栓闭塞性脉管炎 Download PDF

Info

Publication number
CN102006888A
CN102006888A CN2009801134903A CN200980113490A CN102006888A CN 102006888 A CN102006888 A CN 102006888A CN 2009801134903 A CN2009801134903 A CN 2009801134903A CN 200980113490 A CN200980113490 A CN 200980113490A CN 102006888 A CN102006888 A CN 102006888A
Authority
CN
China
Prior art keywords
patient
plasma
specific ligand
column
thromboangiitis obliterans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801134903A
Other languages
English (en)
Chinese (zh)
Inventor
格特·博伊曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CN102006888A publication Critical patent/CN102006888A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CN2009801134903A 2008-04-18 2009-04-20 通过去除自身抗体来治疗血栓闭塞性脉管炎 Pending CN102006888A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08075309A EP2110140A1 (en) 2008-04-18 2008-04-18 Treatment of thromboangiitis obliterans by removal of autoantibodies
EP08075309.8 2008-04-18
PCT/EP2009/002993 WO2009143944A2 (en) 2008-04-18 2009-04-20 Treatment of thromboangiitis obliterans by removal of autoantibodies

Publications (1)

Publication Number Publication Date
CN102006888A true CN102006888A (zh) 2011-04-06

Family

ID=39683905

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801134903A Pending CN102006888A (zh) 2008-04-18 2009-04-20 通过去除自身抗体来治疗血栓闭塞性脉管炎

Country Status (7)

Country Link
US (1) US8663147B2 (enExample)
EP (2) EP2110140A1 (enExample)
JP (1) JP5718807B2 (enExample)
CN (1) CN102006888A (enExample)
CA (1) CA2721061C (enExample)
ES (1) ES2560456T3 (enExample)
WO (1) WO2009143944A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018043629A1 (ja) 2016-09-01 2018-03-08 国立研究開発法人産業技術総合研究所 非天然型立体構造を形成した抗体に親和性を示すポリペプチド

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1409245A1 (ru) 1985-04-12 1988-07-15 Научно-исследовательский институт травматологии и ортопедии Способ лечени врожденного вывиха бедра
SU1409275A1 (ru) * 1985-06-10 1988-07-15 Томский Медицинский Институт Способ лечени псориаза
ATE266415T1 (de) * 1995-11-15 2004-05-15 Edwards Lifesciences Corp Behandlung von dilatierte kardiomyopathie durch entfernung von autoantikoerpern
RU2153168C2 (ru) * 1997-11-25 2000-07-20 Научно-исследовательский институт кардиологии Способ определения показаний к проведению плазмафереза при лечении стенокардии
JP2002533169A (ja) * 1998-12-29 2002-10-08 オキュロジックス コーポレイション レオロジー的処置方法および関連するアフェレーシスシステム
KR20030093316A (ko) * 2001-04-13 2003-12-06 휴먼 게놈 사이언시즈, 인코포레이티드 혈관 내피 성장 인자 ２
DE102006003782A1 (de) * 2006-01-25 2007-08-02 Protagen Ag Immunadsorptionstherapie mittels Autoantigenen
US20100047211A1 (en) * 2006-05-19 2010-02-25 The Johns Hopkins University Method of growth of mesenchymal cells under non-adherent conditions for clinical applications
WO2008048871A2 (en) * 2006-10-18 2008-04-24 Centocor, Inc. Cynomolgus il-13 mutein proteins, antibodies, compositions, methods and uses
WO2008151847A1 (en) * 2007-06-13 2008-12-18 Max-Delbrück-Centrum für Molekulare Medizin Autoantibody binding peptides and their use for the treatment of vascular diseases

Also Published As

Publication number Publication date
EP2110140A1 (en) 2009-10-21
CA2721061A1 (en) 2009-12-03
CA2721061C (en) 2016-06-28
EP2288384B1 (en) 2015-10-28
WO2009143944A3 (en) 2010-08-05
US20110105980A1 (en) 2011-05-05
JP5718807B2 (ja) 2015-05-13
ES2560456T3 (es) 2016-02-19
EP2288384A2 (en) 2011-03-02
US8663147B2 (en) 2014-03-04
WO2009143944A2 (en) 2009-12-03
JP2011517690A (ja) 2011-06-16

Similar Documents

Publication Publication Date Title
Sandborn New concepts in anti-tumor necrosis factor therapy for inflammatory bowel disease
JP4307743B2 (ja) 敗血症療法のための免疫吸着剤
US4865841A (en) Methods and compositions for transient elimination of humoral immune antibodies
CN101611320B (zh) 通过来自胰腺酶原粒的糖蛋白2(gp2)的免疫反应检测体液中抗体的方法用于诊断炎症性肠病和慢性胰腺炎
JP2002504831A (ja) 自己抗体の除去による心筋症の処置
RU2167705C2 (ru) Специфический для пациента иммуноадсорбент для экстракорпорального афереза и способ его получения
JPWO1987001597A1 (ja) β↓２−ミクログロブリン除去カラム
CN100556472C (zh) 分离性输血-设备
Day et al. The association of respiratory infection, recurrent hematuria, and focal glomerulonephritis with activation of the complement system in the cold
JP2013538186A (ja) 活性化増強型抗体の効果を増大させる方法
US20070026396A1 (en) Peptides directed against antibodies, which cause cold-intolerance, and the use thereof
CN102006888A (zh) 通过去除自身抗体来治疗血栓闭塞性脉管炎
Blank et al. Pathogenicity of human anti-platelet factor 4 (PF4)/heparin in vivo: generation of mouse anti-PF4/heparin and induction of thrombocytopenia by heparin
Regnault et al. Specific removal of transthyretin from plasma of patients with familial amyloidotic polyneuropathy: optimization of an immunoadsorption procedure
Ostlund Jr Immunosorbent Chemistry: A Study of Agarose‐Based Column Sorbents for the Removal of Low‐Density Lipoprotein (LDL) from Blood
Nilsson et al. Extracorporeal immunoadsorption therapy on rats. In vivo depletion of specific antibodies
US20090196938A1 (en) Use of a matrix for removing c-reactive protein from biological fluids
CN101538329A (zh) 新的抗β-淀粉样多肽抗体的可变区序列及其编码序列
JPH04228088A (ja) 血小板因子４の生物学的作用を阻害するモノクローナル抗体
US20080255344A1 (en) Immuno-Adsorbers For Treatment of Inflammations
Ren et al. Amelioration of experimental autoimmune myasthenia gravis rats by blood purification treatment using 4‐mercaptoethylpyridine‐based adsorbent
US20100098698A1 (en) Targeted apheresis for the treatment of rheumatoid arthritis
WO2024122553A1 (ja) 潰瘍性大腸炎又は原発性硬化性胆管炎の治療方法
Yamamoto et al. Mass Spectrometry-Based Proteomic Analysis of Adsorbed Molecules in a Hexadecyl-Immobilized Cellulose Beads Column for the Treatment of Dialysis-Related Amyloidosis: FR-OR28
Bambauer et al. Dyslipoproteinemia therapy with lipoprotein-apheresis and/or human monoclonal antibodies

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20110406