CN101987021A - Scattering correction method of CT system and CT system - Google Patents
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Abstract
一种CT系统的散射校正方法,包括以下步骤:获取亮场图像;将散射校正器放置于被扫描物体与探测器之间,进行等角度圆周扫描得到衰减投影图像;分别对被扫描物体和散射校正器进行等角度圆周扫描得到投影图像集和散射校正图像;根据所述亮场图像、散射校正图像以及衰减投影图像生成散射强度分布图;通过所述投影图像集与散射强度分布图之差得到校正后的投影图像集。上述CT系统的散射校正方法及CT系统中,通过将散射校正器置于被扫描物体与探测器之间来消除散射的影响,大大地减少了扫描时间和处理的数据量,有效地提高了效率和精度。
A scatter correction method for a CT system, comprising the following steps: acquiring a bright-field image; placing a scatter corrector between an object to be scanned and a detector, performing equiangular circular scanning to obtain an attenuation projection image; The calibrator performs an equiangular circular scan to obtain a projection image set and a scatter correction image; a scattering intensity distribution map is generated according to the bright field image, a scatter correction image, and an attenuation projection image; and the difference between the projection image set and the scatter intensity distribution map is obtained Corrected set of projected images. In the scatter correction method of the above-mentioned CT system and in the CT system, the influence of scatter is eliminated by placing the scatter corrector between the scanned object and the detector, which greatly reduces the scanning time and the amount of data processed, and effectively improves the efficiency and precision.
Description
【技术领域】【Technical field】
本发明涉及一种仿真成像技术,尤其是一种CT系统的散射校正方法及CT系统。The invention relates to a simulation imaging technology, in particular to a scattering correction method of a CT system and a CT system.
【背景技术】【Background technique】
CT成像技术(computed tomography,电子计算机X射线断层扫描技术)具有对治疗位置进行X线透视、摄片和容积成像的多重功能,在使用CT系统进行透射线成像的过程中,到达探测器的X射线包括两种成分,即初始射线和散射射线。初始射线产生信号进而生成图像,散射射线产生噪声和图像伪影,例如杯状伪影和条纹伪影,从而降低了投影图像的对比度,导致重建的CT值不精确。扇形束CT系统中采用线阵探测器,仅受到一维的散射影响,不会产生大量的散射射线,安装准直器就能达到非常好的散射抑制效果,但是,锥束CT系统由于探测器采用的是面阵探测器,使得散射是二维分布的,接受散射射线的照射要大得多,因此必须设法消除散射的影响。CT imaging technology (computed tomography, electronic computer X-ray tomography technology) has multiple functions of X-ray fluoroscopy, photographing and volume imaging of the treatment position. A ray consists of two components, the initial ray and the scattered ray. The initial rays generate signals and then generate images, and the scattered rays generate noise and image artifacts, such as cupping artifacts and streak artifacts, which reduce the contrast of the projected image and result in inaccurate reconstructed CT values. Linear array detectors are used in fan-beam CT systems, which are only affected by one-dimensional scattering and will not generate a large amount of scattered rays. A very good scattering suppression effect can be achieved by installing a collimator. However, the cone-beam CT system is due to the detector The area array detector is used, so that the scattering is distributed in two dimensions, and the irradiation of scattered rays is much larger, so it is necessary to try to eliminate the influence of scattering.
在锥束CT系统中,由于散射是二维分布,单一的硬件校正或软件校正方法都难以达到理想的效果,因此出现了硬件与软件相结合的混合校正方法,目前的校正方法有以下三种:In the cone-beam CT system, since the scattering is distributed in two dimensions, it is difficult to achieve the desired effect by a single hardware correction or software correction method. Therefore, a hybrid correction method combining hardware and software has emerged. The current correction methods include the following three :
(1)频率调制方法。频率调制方法是将一个具有不同穿透性的网格置于被扫描物体与探测器之间。直射的初级光子与散射光子对于调制器有不同的频率响应特性,即直射光子被调制为高频信号,而散射光子被调制为低频信号,再利用非线性频域滤波器将散射成分从投影图像的频谱中分离。此方法具有散射校正器材简单的优点,但是对于不同的被扫描物体和不同的成像精度,需要调整合适的网格间距。(1) Frequency modulation method. The frequency modulation method is to place a grid with different penetrations between the scanned object and the detector. The direct primary photon and the scattered photon have different frequency response characteristics for the modulator, that is, the direct photon is modulated into a high-frequency signal, while the scattered photon is modulated into a low-frequency signal, and then the scattered component is converted from the projected image by using a nonlinear frequency domain filter. separated in the spectrum. This method has the advantage of simple scattering correction equipment, but for different scanned objects and different imaging precision, it is necessary to adjust the appropriate grid spacing.
(2)初级调制方法。在初级调制方法中,需要制作一个校正片。在一片厚度为2mm的铝板上均匀布满正方形凸部,凸部边长为2mm,间距为2mm,厚度为1mm。校正片作为调制编码器,放置于射线源与被扫描物体之间。初级调制方法的过程可以分为以下几步:由射线源发出的初级射线被校正片“调制编码”,再穿过被扫描物体。在频域上,被探测器所接收的透射射线带有编码信息,散射射线为低频噪声,用高通滤波器对投影滤波,以扣除散射的影响,但是初级调制方法在实际的应用过程中要求非常高,不易于实现。(2) Primary modulation method. In the primary modulation method, a calibration sheet needs to be made. A piece of aluminum plate with a thickness of 2mm is evenly covered with square protrusions, the side length of the protrusions is 2mm, the spacing is 2mm, and the thickness is 1mm. As a modulation encoder, the calibration sheet is placed between the ray source and the object to be scanned. The process of the primary modulation method can be divided into the following steps: the primary ray emitted by the ray source is "modulated and coded" by the calibration sheet, and then passes through the object to be scanned. In the frequency domain, the transmitted ray received by the detector carries coded information, and the scattered ray is low-frequency noise. The high-pass filter is used to filter the projection to deduct the influence of scattering, but the primary modulation method requires very high requirements in the actual application process. high and difficult to achieve.
此外,还可以设定扫描参数后采集空气投影图像和射束衰减网格投影图像,对被检测物体进行圆周扫描,采集带射束衰减网格和被检测物体的投影图像集I和被扫描物体II,计算射束衰减网格中每个金属小球中心的投影位置,采用射束衰减网格校正方法计算与投影图像集I中的投影图像一一对应的散射场分布图像,将投影图像集I减去对应的散射场分布图像得到散射校正后的投影图像集III,由此通过FBP(Filtered Back Projection,滤过反投影)算法重建出散射校正后的序列切片序列。在此方法中,将射束衰减网格放置在射线源与被扫描物体之间,靠近被扫描物体,由于出射光首先穿过射束衰减网格,导致出射光光谱发生变化。另外,对于同一被扫描物体,要扫描两次,扫描时间增加一倍,处理的数据量也增加了一倍,效率非常低。In addition, after setting the scanning parameters, the air projection image and the beam attenuation grid projection image can be collected, and the object to be detected can be scanned circularly, and the projection image set I with the beam attenuation grid and the object to be detected can be collected and the object to be scanned II. Calculate the projection position of the center of each metal ball in the beam attenuation grid, use the beam attenuation grid correction method to calculate the scattered field distribution image corresponding to the projection image in the projection image set I, and convert the projection image set to I subtracted the corresponding scattering field distribution image to obtain the projection image set III after scattering correction, and then reconstructed the serial slice sequence after scattering correction through the FBP (Filtered Back Projection) algorithm. In this method, the beam attenuation grid is placed between the ray source and the scanned object, close to the scanned object, since the outgoing light first passes through the beam attenuation grid, the spectrum of the outgoing light changes. In addition, for the same scanned object, it needs to be scanned twice, the scanning time is doubled, and the amount of processed data is also doubled, which is very inefficient.
【发明内容】【Content of invention】
基于此,有必要提供一种可提高效率的CT系统的散射校正方法。Based on this, it is necessary to provide a scatter correction method for a CT system that can improve efficiency.
此外,还有必要提供一种可提高效率的CT系统。In addition, there is a need to provide a CT system that can improve efficiency.
一种CT系统的散射校正方法,包括以下步骤:获取亮场图像;将散射校正器放置于被扫描物体与探测器之间,进行等角度圆周扫描得到衰减投影图像;分别对被扫描物体和散射校正器进行等角度圆周扫描得到投影图像集和散射校正图像;根据所述亮场图像、散射校正图像以及衰减投影图像生成散射强度分布图;通过所述投影图像集与散射强度分布图之差得到校正后的投影图像集。A scatter correction method for a CT system, comprising the following steps: acquiring a bright-field image; placing a scatter corrector between an object to be scanned and a detector, performing equiangular circular scanning to obtain an attenuation projection image; The calibrator performs an equiangular circular scan to obtain a projection image set and a scatter correction image; a scattering intensity distribution map is generated according to the bright field image, a scatter correction image, and an attenuation projection image; and the difference between the projection image set and the scatter intensity distribution map is obtained Corrected set of projected images.
优选地,所述散射校正器是在薄板中嵌入小球,所述薄板的吸收系数小于所述小球的吸收系数。Preferably, the scattering corrector is a small ball embedded in a thin plate, the absorption coefficient of the thin plate is smaller than that of the small ball.
优选地,所述小球在所述薄板中呈棋盘分布。Preferably, said pellets are distributed in a checkerboard manner in said sheet.
优选地,所述根据所述亮场图像、散射校正图像以及衰减投影图像生成散射强度分布图的步骤为:通过遗传算法从散射校正图像中得到各个投影圆的中心坐标;从亮场图像中得到与所述各个投影圆相对应的初始射线强度,并从散射校正图像中得到与所述各个投影圆相对应的穿过散射校正器后的射线强度以及校正的总射线强度;从投影图像集中获取物体总射线强度;通过所述初始射线强度、穿过散射校正器后的射线强度、校正的总射线强度以及物体总射线强度得到衰减投影图像中的散射值分布;对所述散射值分布进行二维插值及角度插值得到散射强度分布图。Preferably, the step of generating a scattering intensity distribution map according to the bright field image, the scattering correction image and the attenuation projection image is: obtaining the center coordinates of each projection circle from the scattering correction image through a genetic algorithm; obtaining The initial ray intensity corresponding to each projection circle, and obtain the ray intensity corresponding to each projection circle after passing through the scattering corrector and the corrected total ray intensity from the scatter correction image; obtain from the projection image set The total ray intensity of the object; the scatter value distribution in the attenuation projection image is obtained by the initial ray intensity, the ray intensity after passing through the scatter corrector, the corrected total ray intensity and the total ray intensity of the object; the scatter value distribution is binary Dimensional interpolation and angle interpolation are used to obtain the distribution map of scattering intensity.
优选地,所述通过所述投影图像集与散射强度分布图之差得到校正后的投影图像集的步骤之后还包括:对所述校正后的投影图像集进行图像重建。Preferably, after the step of obtaining the corrected projection image set through the difference between the projection image set and the scattering intensity distribution map, the step further includes: performing image reconstruction on the corrected projection image set.
一种CT系统,至少包括:扫描模块,用于获取亮场图像,对被扫描物体以及置于所述被扫描物体与探测器之间的散射校正器进行等角度扫描得到衰减投影图像,并分别对被扫描物体和散射校正器进行等角度圆周扫描得到投影图像集和散射校正图像;处理模块,用于根据所述亮场图像、散射校正图像以及衰减投影图像生成散射强度分布图;校正模块,用于通过所述投影图像集与散射强度分布图之差得到校正后的投影图像集。A CT system at least includes: a scanning module, configured to acquire a bright-field image, perform equiangular scanning on an object to be scanned and a scatter corrector placed between the object to be scanned and a detector to obtain an attenuated projection image, and respectively Perform equiangular circular scanning on the scanned object and the scatter corrector to obtain a projection image set and a scatter correction image; a processing module is used to generate a scatter intensity distribution map according to the bright field image, the scatter correction image and the attenuation projection image; the correction module, A corrected projection image set is obtained by using the difference between the projection image set and the scattering intensity distribution map.
优选地,所述散射校正器是在薄板中嵌入小球,所述薄板的吸收系数小于所述小球的吸收系数。Preferably, the scattering corrector is a small ball embedded in a thin plate, the absorption coefficient of the thin plate is smaller than that of the small ball.
优选地,所述小球在所述薄板中呈棋盘分布。Preferably, said pellets are distributed in a checkerboard manner in said sheet.
优选地,所述处理模块包括:位置获取单元,用于通过遗传算法从散射校正图像中得到各个投影圆的中心坐标;强度获取单元,用于从亮场图像中得到与所述各个投影圆相对应的初始射线强度,并从散射校正图像中得到与所述各个投影圆相对应的穿过散射校正器后的射线强度以及校正的总射线强度,从投影图像集中获取物体总射线强度;计算单元,用于通过所述初始射线强度、穿过散射校正器后的射线强度、校正的总射线强度以及物体总射线强度得到衰减投影图像中的散射值分布;插值单元,用于对所述散射值分布进行二维插值及角度插值,得到散射强度分布图。Preferably, the processing module includes: a position acquisition unit, used to obtain the center coordinates of each projection circle from the scatter correction image through a genetic algorithm; an intensity acquisition unit, used to obtain the center coordinates of each projection circle from the bright field image The corresponding initial ray intensity, and obtain the ray intensity corresponding to each projection circle after passing through the scatter corrector and the corrected total ray intensity from the scatter correction image, and obtain the total ray intensity of the object from the projection image set; the calculation unit , used to obtain the scatter value distribution in the attenuation projection image through the initial ray intensity, the ray intensity after passing through the scatter corrector, the corrected total ray intensity and the total ray intensity of the object; the interpolation unit is used to calculate the scatter value Two-dimensional interpolation and angle interpolation are performed on the distribution to obtain the distribution map of scattering intensity.
优选地,还包括:重建模块,用于对所述校正后的投影图像集进行图像重建。上述CT系统的散射校正方法及CT系统中,通过将散射校正器置于被扫描物体与探测器之间来消除散射的影响,大大地减少了扫描时间和处理的数据量,有效地提高了效率和精度。Preferably, it further includes: a reconstruction module, configured to perform image reconstruction on the corrected projection image set. In the scatter correction method of the above-mentioned CT system and in the CT system, the influence of scatter is eliminated by placing the scatter corrector between the scanned object and the detector, which greatly reduces the scanning time and the amount of data processed, and effectively improves the efficiency and precision.
上述CT系统的散射校正方法及CT系统中的散射校正器结构简单,制造成本低廉,易于实现并适用于被扫描物体性质变化非常较的环境。The scatter correction method for the CT system and the scatter corrector in the CT system are simple in structure, low in manufacturing cost, easy to implement, and suitable for environments where the properties of scanned objects vary greatly.
【附图说明】【Description of drawings】
图1为一个实施例中CT系统的散射校正方法;Fig. 1 is a scatter correction method of a CT system in an embodiment;
图2为一个实施例中的散射校正器的示意图;Figure 2 is a schematic diagram of a scatter corrector in one embodiment;
图3为一个实施例中根据亮场图像、散射校正图像以及衰减投影图像生成散射强度分布图的流程图;Fig. 3 is a flow chart of generating a scattering intensity distribution map according to a bright field image, a scattering correction image and an attenuation projection image in one embodiment;
图4为一个实施例中扫描亮场的示意图;Fig. 4 is a schematic diagram of scanning bright field in an embodiment;
图5为一个实施例中放置被扫描物体并添加散射校正器的示意图;Fig. 5 is a schematic diagram of placing an object to be scanned and adding a scatter corrector in one embodiment;
图6为一个实施例中仅扫描被扫描物体的示意图;Fig. 6 is a schematic diagram of scanning only the scanned object in one embodiment;
图7为一个实施例中仅扫描散射校正器的示意图;Figure 7 is a schematic diagram of a scanning-only scatter corrector in one embodiment;
图8为一个实施例中CT系统的详细模块图;Figure 8 is a detailed block diagram of the CT system in one embodiment;
图9为一个实施例中处理模块的示意图。Figure 9 is a schematic diagram of a processing module in one embodiment.
【具体实施方式】【Detailed ways】
图1示出了一个实施例中CT系统的散射校正方法,包括以下步骤:Fig. 1 shows a scatter correction method of a CT system in an embodiment, including the following steps:
在步骤S10中,获取亮场图像。本实施例中,扫描视场中不放置任何物体,扫描亮场得到亮场图像。成像视场中不放置被扫描物体,并打开光源所扫描得到的图像为这场图像。In step S10, a bright field image is acquired. In this embodiment, no object is placed in the scanning field of view, and the bright field image is obtained by scanning the bright field. The scanned object is not placed in the imaging field of view, and the scanned image obtained by turning on the light source is the current image.
在步骤S20中,将散射校正器放置于被扫描物体与探测器之间,进行等角度圆周扫描得到衰减投影图像。本实施例中,如图2所示,散射校正器(scattercorrection device,SCD)是在薄板中嵌入小球,薄板的吸收系数小于小球的吸收系数。小球在薄板中呈棋盘分布。散射校正器的大小可介于被扫描物体与探测器之间,为使实际的操作中更简便,可使散射校正器的尺寸与探测器的尺寸一致即可满足需要,即优选为50mm*50mm~500mm*500mm的范围内。对于散射校正器的厚度必须保证大于小球半径,这样才可以将小球固定,因此散射校正器的厚度优选为1mm~50mm的范围内。在具体的实施例中,选用大小为50mm*50mm,厚度为1mm~5mm的散射校正器。另一实施例中,小球也可采用其他的分布方式,其直径取决于实际情况,例如,对目前工业和医用CT系统而言,小球的参数是:直径范围值为0.5mm~20mm;孔深范围值为0.25mm~10mm;中心间距的范围值为1mm~40mm。在优选的实施例中,直径范围值为0.5mm~1.5mm;孔深范围值为0.25mm~1mm;中心间距的范围值为1mm~4mm。薄板优选为聚乙烯塑料板,但也可以采用其它低吸收系数的材料,例如硬纸板、薄木片等,小球优选为金属小球,但也可以是其它高吸收材料,例如铅球。In step S20, the scattering corrector is placed between the object to be scanned and the detector, and an equiangular circular scan is performed to obtain an attenuation projection image. In this embodiment, as shown in FIG. 2 , the scatter correction device (SCD) is embedded with small balls in the thin plate, and the absorption coefficient of the thin plate is smaller than that of the small balls. The pellets are distributed in a checkerboard pattern in the sheet. The size of the scatter corrector can be between the scanned object and the detector. In order to make the actual operation easier, the size of the scatter corrector can be consistent with the size of the detector to meet the needs, that is, preferably 50mm*50mm ~500mm*500mm range. The thickness of the scatter corrector must be greater than the radius of the ball so that the sphere can be fixed. Therefore, the thickness of the scatter corrector is preferably in the range of 1 mm to 50 mm. In a specific embodiment, a scattering corrector with a size of 50mm*50mm and a thickness of 1mm-5mm is selected. In another embodiment, the balls can also be distributed in other ways, and the diameter depends on the actual situation. For example, for the current industrial and medical CT systems, the parameters of the balls are: the diameter range is 0.5 mm to 20 mm; The range of hole depth is 0.25mm to 10mm; the range of center distance is 1mm to 40mm. In a preferred embodiment, the diameter ranges from 0.5 mm to 1.5 mm; the hole depth ranges from 0.25 mm to 1 mm; the center-to-center distance ranges from 1 mm to 4 mm. The thin plate is preferably a polyethylene plastic plate, but other materials with low absorption coefficient can also be used, such as cardboard, wood veneer, etc. The pellets are preferably metal pellets, but can also be other high absorption materials, such as lead balls.
在X射线穿过被扫描物体进入探测器的过程中,如果射线没有与被扫描物体发生反应,则这种射线可以称为初始射线,如果发生了反应,则X射线能量范围为0.1~1MeV时主要是由于康普顿效应而产生的,这种射线可以称为散射射线。因此,在探测器上所吸收的射线由两部分组成,即初始射线和散射射线,对于工业CT和医用CT,能量范围在0kv~450kv的散射射线大多由康普顿效应产生,而锥束CT系统中能量范围在20kv~90kv的低能系统也存在着散射射线,在扫描过程中通过散射校正器的作用消除散射射线的影响。In the process of X-rays passing through the scanned object and entering the detector, if the ray does not react with the scanned object, this ray can be called the initial ray. If there is a reaction, the X-ray energy ranges from 0.1 to 1 MeV. Mainly due to the Compton effect, this kind of ray can be called scattered ray. Therefore, the radiation absorbed by the detector consists of two parts, namely the initial radiation and the scattered radiation. For industrial CT and medical CT, the scattered radiation in the energy range of 0kv ~ 450kv is mostly produced by the Compton effect, while the cone beam CT Scattered rays also exist in the low-energy system with an energy range of 20kv to 90kv in the system, and the influence of scattered rays is eliminated by the function of the scattering corrector during the scanning process.
对于散射校正器的位置,在视场中散射校正器有四个位置可以放置:(1)散射校正器放置于靠近光源的位置;(2)将散射校正器放置于被扫描物体和探测器之间靠近被扫描物体的位置;(3)将散射校正器放置于被扫描物体与探测器之间靠近被扫描物体的位置;(4)将散射校正器放置于被扫描物体与探测器之间靠近探测器的位置。对于位置(1)和位置(2),沿射线的传播方向,散射校正器放置于被扫描物体前,此时射线首先穿过散射校正器,散射分布还未形成;对于位置(4),由于散射校正器紧贴探测器,散射校正器中的小球会吸收初始射线和散射射线,因而会改变散射的强度分布;只有位置(3)在射线穿过被扫描物体后,散射分布已经形成,此时再穿过散射校正器,由小球吸收初始射线,即尚未改变方向的射线,由此在探测器上的相应位置所得到的就是散射射线和衰减后的初始射线。由此可知,在扫描过程中,将散射校正器放置于被扫描物体与探测器之间,并尽量靠近被扫描物体。As for the position of the scatter corrector, there are four positions for the scatter corrector to be placed in the field of view: (1) the scatter corrector is placed close to the light source; (2) the scatter corrector is placed between the scanned object and the detector (3) place the scatter corrector between the scanned object and the detector close to the scanned object; (4) place the scatter corrector between the scanned object and the detector close to The position of the detector. For position (1) and position (2), the scatter corrector is placed in front of the object to be scanned along the propagation direction of the ray, at this time the ray first passes through the scatter corrector, and the scattering distribution has not yet formed; for position (4), due to The scatter corrector is close to the detector, and the ball in the scatter corrector will absorb the initial ray and the scattered ray, thus changing the intensity distribution of the scatter; only position (3) after the ray passes through the scanned object, the scatter distribution has been formed, At this time, it passes through the scattering corrector, and the ball absorbs the initial ray, that is, the ray that has not changed its direction, so what is obtained at the corresponding position on the detector is the scattered ray and the attenuated initial ray. It can be seen that, during the scanning process, the scattering corrector is placed between the object to be scanned and the detector, and as close as possible to the object to be scanned.
由于散射强度分布的空间变化不大,因此即使增加扫描角度间隔,散射强度分布变化仍然不大,附加了散射校正器后只需要进行等角度圆周扫描60次,得到60幅图像即可。Since the spatial variation of the scattering intensity distribution is not large, even if the scanning angle interval is increased, the variation of the scattering intensity distribution is still small. After adding the scattering corrector, only 60 equiangular circular scans are required to obtain 60 images.
在步骤S30中,分别对被扫描物体和散射校正器进行等角度扫描得到投影图像集和散射校正图像。本实施例中,仅在视场中放置被扫描物体,对被扫描物体进行等角度间隔的圆周扫描360次,得到投影图像集,然后撤去被扫描物体,仅放置散射校正器进行扫描,得到散射校正图像。In step S30, the scanned object and the scatter corrector are scanned at equal angles to obtain a projected image set and a scatter corrected image. In this embodiment, only the scanned object is placed in the field of view, and the scanned object is scanned 360 times at equal angular intervals to obtain a projection image set, and then the scanned object is removed, and only the scattering corrector is placed for scanning to obtain the scattering Correct the image.
在步骤S40中,根据亮场图像、散射校正图像以及衰减投影图像生成散射强度分布图。本实施例中,分别从亮场图像、散射校正图像以及衰减投影图像中提取数据,并通过遗传算法以及朗伯定律生成散射强度分布图,以用于校正投影图像集。In step S40, a scattering intensity distribution map is generated according to the bright field image, the scattering correction image and the attenuation projection image. In this embodiment, data are extracted from bright field images, scatter correction images, and attenuation projection images respectively, and a scattering intensity distribution map is generated by genetic algorithm and Lambert's law, so as to correct the projection image set.
在一个具体的实施例中,如图3所示,根据亮场图像、散射校正图像以及衰减投影图像生成散射强度分布图的步骤为:In a specific embodiment, as shown in FIG. 3, the steps of generating a scattering intensity distribution map according to the bright field image, the scattering correction image and the attenuation projection image are:
在步骤S401中,通过遗传算法从散射校正图像中得到各个投影圆的中心坐标。本实施例中,由散射校正图像中获得一系列的小球投影圆图像,从而通过遗传算法求出各个投影圆的中心坐标,例如,可应用Matlab编写程序,采用遗传算法,在投影圆中找到一点和一个半径,使得各点到这点的距离与半径之差的平方和最小,即可求出散射校正图像中各个投影圆的中心坐标。In step S401, the center coordinates of each projection circle are obtained from the scatter-corrected image through a genetic algorithm. In this embodiment, a series of small ball projection circle images are obtained from the scatter correction image, so as to obtain the center coordinates of each projection circle through a genetic algorithm. For example, Matlab can be used to write a program, and a genetic algorithm can be used to find One point and one radius, so that the sum of the squares of the distance from each point to this point and the radius is the smallest, and then the center coordinates of each projection circle in the scatter-corrected image can be obtained.
在步骤S402中,从亮场图像中得到与各个投影圆相对应的初始射线强度,并从散射校正图像中得到与各个投影圆相对应的穿过散射校正器后的射线强度,从衰减投影图像中得到校正的总射线强度。本实施例中,如图4所示,可从亮场图像中分别测量得到各投影圆中心坐标的对应点的初始射线强度I0,根据各个投影圆的中心坐标,从散射校正图像中得到相应的穿过散射校正器后的射线强度I3,如图5所示,在衰减投影图像中测量得到校正的总射线强度D1。校正的总射线强度D1是将散射校正器置于被扫描物体和探测器之间时探测器上所接收到的总射线强度。In step S402, the initial ray intensity corresponding to each projection circle is obtained from the bright field image, and the ray intensity corresponding to each projection circle after passing through the scattering corrector is obtained from the scatter correction image, and the attenuation projection image The corrected total ray intensity in . In this embodiment, as shown in Figure 4, the initial ray intensity I 0 of the corresponding point of the center coordinates of each projection circle can be measured separately from the bright field image, and the corresponding ray intensity I 0 can be obtained from the scattering correction image according to the center coordinates of each projection circle. The ray intensity I 3 after passing through the scattering corrector, as shown in FIG. 5 , is measured in the attenuation projection image to obtain the corrected total ray intensity D 1 . The corrected total ray intensity D1 is the total ray intensity received on the detector when the scatter corrector is placed between the scanned object and the detector.
在步骤S403中,从投影图像集中获取物体总射线强度。本实施例中,如图6所示,在投影图像集中所测量得到的物体总射线强度D2是仅放置被扫描物体,对被扫描物体进行等角度间隔扫描360次时探测器上接收到的总射线强度。In step S403, the total ray intensity of the object is obtained from the projection image set. In this embodiment, as shown in Figure 6, the total ray intensity D2 of the object measured in the projected image set is the value received by the detector when only the scanned object is placed and the scanned object is scanned 360 times at equal angular intervals. total ray intensity.
在步骤S404中,通过初始射线强度、穿过散射校正器后的射线强度、校正的总射线强度以及物体总射线强度得到衰减投影图像中的散射值分布。本实施例中,根据朗伯定律,如图5至7所示,由图6可以得到公式(1),由图5可以得到公式(2)和公式(3),由图7可以得到公式(4):In step S404, the scatter value distribution in the attenuation projection image is obtained through the initial ray intensity, the ray intensity after passing through the scatter corrector, the corrected total ray intensity, and the total object ray intensity. In the present embodiment, according to Lambert's law, as shown in Figures 5 to 7, formula (1) can be obtained by Figure 6, formula (2) and formula (3) can be obtained by Figure 5, formula (3) can be obtained by Figure 7 4):
I2=D1-S……(3)I 2 =D 1 -S...(3)
其中,μ1为被扫描物体的线性衰减系数,μ2为散射校正器中小球的线性衰减系数,l1为穿过被扫描物体的路径长度,l2为小球的直径,S为散射射线强度,I1为穿过被扫描物体的射线强度,I2为穿过小球的射线强度。Among them, μ 1 is the linear attenuation coefficient of the scanned object, μ 2 is the linear attenuation coefficient of the small ball in the scattering corrector, l 1 is the path length through the scanned object, l 2 is the diameter of the small ball, and S is the scattered ray Intensity, I 1 is the intensity of rays passing through the scanned object, and I 2 is the intensity of rays passing through the ball.
将公式(1)带入(2)得: Put formula (1) into (2) to get:
由公式(2)将公式(2)带入公式(5)得: By formula (2) Put formula (2) into formula (5) to get:
由公式(6)得到可求出衰减投影图像中各个投影圆的散射射线强度S,进而得到所有衰减投影图像中各个小球的散射值分布。According to the formula (6), the scattered ray intensity S of each projection circle in the attenuation projection image can be obtained, and then the scattering value distribution of each small ball in all attenuation projection images can be obtained.
在步骤S405中,对散射值分布进行二维插值及角度插值得到散射强度分布图。本实施例中,由于散射射线强度空间变化缓慢,空间频率较低,因此可以对散射值分布中的每一幅图像进行二维插值,得到与衰减投影图像数量相同的散射强度分布图。此时通过经过二维插值后的散射强度分布图中同一个像素位置的点进行角度插值,得到一组共与投影图像集相对应的散射强度分布图。In step S405, two-dimensional interpolation and angle interpolation are performed on the distribution of scattering values to obtain a distribution diagram of scattering intensity. In this embodiment, since the spatial variation of scattered ray intensity is slow and the spatial frequency is low, two-dimensional interpolation can be performed on each image in the scatter value distribution to obtain the same number of scatter intensity distribution maps as the attenuation projection images. At this time, angle interpolation is performed on points at the same pixel position in the scattering intensity distribution map after two-dimensional interpolation to obtain a set of scattering intensity distribution maps corresponding to the projection image set.
在步骤S50中,通过投影图像集与散射强度分布图之差得到校正后的投影图像集。本实施例中,用投影图像集依次减去散射强度分布图就得到了校正后的图像。In step S50, the corrected projection image set is obtained by the difference between the projection image set and the scattering intensity distribution map. In this embodiment, the corrected image is obtained by sequentially subtracting the scattering intensity distribution map from the projected image set.
在其他实施例中,上述CT系统的散射校正方法还包括了对校正后的投影图像集进行图像重建的步骤。本实施例中,可应用BPF算法(BackprojectionFiltration,反投影滤波型重建算法)进行图像重建。In other embodiments, the scatter correction method for the above CT system further includes the step of performing image reconstruction on the corrected projection image set. In this embodiment, a BPF algorithm (Backprojection Filtration, back-projection filtering reconstruction algorithm) may be used for image reconstruction.
此外,还有必要提供一种应用了上述散射校正方法的CT系统,如图8所示,该系统至少包括扫描模块10、处理模块20以及校正模块30。In addition, it is also necessary to provide a CT system to which the above scatter correction method is applied. As shown in FIG. 8 , the system at least includes a
扫描模块10,用于获取亮场图像,对被扫描物体以及置于被扫描物体与探测器之间的散射校正器进行等角度扫描得到衰减投影图像,并分别对被扫描物体和散射校正器进行等角度圆周扫描得到投影图像集和散射校正图像。本实施例中,成像视场中不放置被扫描物体,并打开光源所扫描得到的图像为这场图像。散射校正器指的是在薄板中嵌入小球,薄板的吸收系数小于小球的吸收系数。小球在薄板中呈棋盘分布。散射校正器的大小可介于被扫描物体与探测器之间,为使实际的操作中更简便,可使散射校正器的尺寸与探测器的尺寸一致即可满足需要,即优选为50mm*50mm~500mm*500mm的范围内。对于散射校正器的厚度必须保证大于小球半径,这样才可以将小球固定,因此散射校正器的厚度优选为1mm~50mm的范围内。在具体的实施例中,选用大小为50mm*50mm,厚度为1mm~5mm的散射校正器。另一实施例中,小球也可采用其他的分布方式,其直径取决于实际情况,例如,对目前工业和医用CT系统而言,小球的参数是:直径范围值为0.5mm~20mm;孔深范围值为0.25mm~10mm;中心间距的范围值为1mm~40mm。在优选的实施例中,直径范围值为0.5mm~1.5mm;孔深范围值为0.25mm~1mm;中心间距的范围值为1mm~4mm。薄板优选为聚乙烯塑料板,但也可以采用其它低吸收系数的材料,例如硬纸板、薄木片等,小球优选为金属小球,但也可以是其它高吸收材料,例如铅球。The
在X射线穿过被扫描物体进入探测器的过程中,如果射线没有与被扫描物体发生反应,则这种射线可以称为初始射线,如果发生了反应,则X射线能量范围为0.1~1MeV时主要是由于康普顿效应而产生的,这种射线可以称为散射射线。因此,在探测器上所吸收的射线由两部分组成,即初始射线和散射射线,对于工业CT和医用CT,能量范围在0kv~450kv的散射射线大多由康普顿效应产生,而锥束CT中能量范围在20kv~90kv的低能系统也存在着散射射线,在扫描过程中通过散射校正器的作用消除散射射线的影响。In the process of X-rays passing through the scanned object and entering the detector, if the ray does not react with the scanned object, this ray can be called the initial ray. If there is a reaction, the X-ray energy ranges from 0.1 to 1 MeV. Mainly due to the Compton effect, this kind of ray can be called scattered ray. Therefore, the radiation absorbed by the detector consists of two parts, namely the initial radiation and the scattered radiation. For industrial CT and medical CT, the scattered radiation in the energy range of 0kv ~ 450kv is mostly produced by the Compton effect, while the cone beam CT Scattered rays also exist in low-energy systems with medium energy ranging from 20kv to 90kv. During the scanning process, the effect of scattered rays is eliminated by the function of the scattering corrector.
对于散射校正器的位置,在视场中散射校正器有四个位置可以放置:(1)散射校正器放置于靠近光源的位置;(2)将散射校正器放置于被扫描物体和探测器之间靠近被扫描物体的位置;(3)将散射校正器放置于被扫描物体与探测器之间靠近被扫描物体的位置;(4)将散射校正器放置于被扫描物体与探测器之间靠近探测器的位置。对于位置(1)和位置(2),沿射线的传播方向,散射校正器放置于被扫描物体前,此时射线首先穿过散射校正器,散射分布还未形成;对于位置(4),由于散射校正器紧贴探测器,散射校正器中的小球会吸收初始射线和散射射线,因而会改变散射的强度分布;只有位置(3)在射线穿过被扫描物体后,散射分布已经形成,此时再穿过散射校正器,由小球吸收初始射线,即尚未改变方向的射线,由此在探测器上的相应位置所得到的就是散射射线和衰减后的初始射线。由此可知,在扫描过程中,将散射校正器放置于被扫描物体与探测器之间,并尽量靠近被扫描物体。As for the position of the scatter corrector, there are four positions for the scatter corrector to be placed in the field of view: (1) the scatter corrector is placed close to the light source; (2) the scatter corrector is placed between the scanned object and the detector (3) place the scatter corrector between the scanned object and the detector close to the scanned object; (4) place the scatter corrector between the scanned object and the detector close to The position of the detector. For position (1) and position (2), the scatter corrector is placed in front of the object to be scanned along the propagation direction of the ray, at this time the ray first passes through the scatter corrector, and the scattering distribution has not yet formed; for position (4), due to The scatter corrector is close to the detector, and the ball in the scatter corrector will absorb the initial ray and the scattered ray, thus changing the intensity distribution of the scatter; only position (3) after the ray passes through the scanned object, the scatter distribution has been formed, At this time, it passes through the scattering corrector, and the ball absorbs the initial ray, that is, the ray that has not changed its direction, so what is obtained at the corresponding position on the detector is the scattered ray and the attenuated initial ray. It can be seen that, during the scanning process, the scattering corrector is placed between the object to be scanned and the detector, and as close as possible to the object to be scanned.
扫描视场中不放置任何物体,扫描模块10扫描亮场得到亮场图像。由于散射强度分布的空间变化不大,因此即使增加扫描角度间隔,散射强度分布变化仍然不大,附加了散射校正器后扫描模块10只需要进行等角度圆周扫描60次,得到60幅图像即可。No object is placed in the scanning field of view, and the
仅在视场中放置被扫描物体,扫描模块10对被扫描物体进行等角度间隔的圆周扫描360次,得到投影图像集,然后撤去被扫描物体,仅放置散射校正器进行扫描,得到散射校正图像。Only the scanned object is placed in the field of view, and the
处理模块20,用于根据亮场图像、散射校正图像以及衰减投影图像生成散射强度分布图。本实施例中,处理模块20分别从亮场图像、散射校正图像以及衰减投影图像中提取数据,并通过遗传算法以及朗伯定律生成散射强度分布图,以用于校正投影图像集。The
在一个具体的实施例中,如图9所示,处理模块20包括位置获取单元201、强度获取单元202、计算单元203以及插值单元204。In a specific embodiment, as shown in FIG. 9 , the
位置获取单元201,用于通过遗传算法从散射校正图像中得到各个投影圆的中心坐标。本实施例中,位置获取单元201由散射校正图像中获得一系列的高吸收系数的小球投影圆图像,从而通过遗传算法求出各个投影圆的中心坐标,例如,位置获取单元201可应用Matlab编写程序,采用遗传算法,在投影圆中找到一点和一个半径,使得各点到这点的距离与半径之差的平方和最小,即可求出散射校正图像中各个投影圆的中心坐标。The
强度获取单元202,用于从亮场图像中得到与各个投影圆相对应的初始射线强度,并从散射校正图像中得到与各个投影圆相对应的穿过散射校正器后的射线强度以及校正的总射线强度,从投影图像集中获取物体总射线强度。本实施例中,强度获取单元202可从亮场图像中分别测量得到各投影圆中心坐标的对应点的初始射线强度I0,根据各个投影圆的中心坐标,从散射校正图像中得到相应的穿过散射校正器后的射线强度I3,在衰减投影图像中测量得到校正的总射线强度D1。校正的总射线强度D1是将散射校正器置于被扫描物体和探测器之间时探测器上所接收到的总射线强度。强度获取单元202在投影图像集中所测量得到的总射线强度D2是仅放置被扫描物体,对被扫描物体进行等角度间隔扫描360次时探测器上接收到的总射线强度。The
计算单元203,用于通过初始射线强度、穿过散射校正器后的射线强度、校正的总射线强度以及物体总射线强度得到衰减投影图像中的散射值分布。本实施例中,计算单元203根据朗伯定律,由以下公式计算得到衰减投影图像中的散射值分布。The
I2=D1-S……(3)I 2 =D 1 -S...(3)
其中,μ1为被扫描物体的线性衰减系数,μ2为散射校正器中小球的线性衰减系数,l1为穿过被扫描物体的路径长度,l2为小球的直径,S为散射射线强度,I1为穿过被扫描物体的射线强度,I2为穿过小球的射线强度。Among them, μ 1 is the linear attenuation coefficient of the scanned object, μ 2 is the linear attenuation coefficient of the small ball in the scattering corrector, l 1 is the path length through the scanned object, l 2 is the diameter of the small ball, and S is the scattered ray Intensity, I 1 is the intensity of rays passing through the scanned object, and I 2 is the intensity of rays passing through the ball.
将公式(1)带入(2)得: Put formula (1) into (2) to get:
由公式(2)将公式(2)带入公式(5)得: By formula (2) Put formula (2) into formula (5) to get:
由公式(6)得到可求出衰减投影图像中各个投影圆的散射射线强度S,进而得到所有衰减投影图像中各个小球的散射值分布。According to the formula (6), the scattered ray intensity S of each projection circle in the attenuation projection image can be obtained, and then the scattering value distribution of each small ball in all attenuation projection images can be obtained.
插值单元204,用于对散射值分布进行二维插值及角度插值,得到散射强度分布图。本实施例中,由于散射射线强度空间变化缓慢,空间频率较低,因此插值单元204可以对散射值分布中的每一幅图像进行二维插值,得到与衰减投影图像数量相同的散射强度分布图。此时通过经过二维插值后的散射强度分布图中同一个像素位置的点进行角度插值,得到一组共与投影图像集相对应的散射强度分布图。The
校正模块30,用于通过投影图像集与散射强度分布图之差得到校正后的投影图像集。本实施例中,校正模块30用投影图像集依次减去散射强度分布图就得到了校正后的图像。The
在其他实施例中,上述CT系统还包括了重建模块,该重建模块用于对校正后的投影图像集进行图像重建。本实施例中,重建模块可应用BPF算法进行图像重建。In other embodiments, the above-mentioned CT system further includes a reconstruction module, which is used to perform image reconstruction on the corrected projection image set. In this embodiment, the reconstruction module can apply the BPF algorithm to perform image reconstruction.
下面结合一个详细的实施例阐述上述CT系统的散射校正方法及CT系统的应用过程。该实施例中,由散射校正图像可获得一系列的小球投影圆图像,并采用遗传算法在投影圆中找到一点和一个半径R,使各点到这点的距离与R之差的平方和最小,即可求出散射校正图像中各个投影圆中心坐标(ui,vi)。The scatter correction method of the above-mentioned CT system and the application process of the CT system will be described below in conjunction with a detailed embodiment. In this embodiment, a series of small ball projection circle images can be obtained from the scatter correction image, and a point and a radius R are found in the projection circle using a genetic algorithm, so that the sum of the squares of the distances from each point to this point and R The minimum coordinates (u i , v i ) of each projected circle center in the scatter-corrected image can be obtained.
在亮场图像中,可以分别测量得到(ui,vi)对应点的初始射线强度I0的值,在散射校正图像中可以测量得到与(ui,vi)相对应的I3值。由公式(4)即可算出在衰减投影图像和投影图像集中分别测量(ui,vu)对应点的校正的总射线强度D1和物体总射线强度D2,由公式(6)可以得出衰减投影图像中的散射值分布。In the bright-field image, the value of the initial ray intensity I 0 corresponding to the point (u i , v i ) can be measured separately, and the value of I 3 corresponding to (u i , v i ) can be measured in the scatter-corrected image . It can be calculated by formula (4) Measure the corrected total ray intensity D 1 of the corresponding point (u i , v u ) and the total ray intensity D 2 of the object in the attenuation projection image and the projection image set respectively, and the scattering value in the attenuation projection image can be obtained from the formula (6) distributed.
对散射值分布进行二维插值,得逐角度插值从而得到散射强度分布图。投影图像集与散射强度分布图之差即为校正后的投影图像集。Two-dimensional interpolation is performed on the distribution of scattering values, and interpolation by angle is obtained to obtain the distribution map of scattering intensity. The difference between the projection image set and the scattering intensity distribution map is the corrected projection image set.
例如,假设由散射校正图像计算得到一个投影圆中心坐标为(800,500),在亮场图像中,测量得到I0为10000.在散射校正图像中得到I3为5000,则由公式(4)得在衰减投影图像中得到(800,500)位置的D1为2000,由投影图像集得到(800,500)位置的D2为3000,则由公式(6)可求出(800,500)位置的散射射线强度进而得到散射值分布。For example, assuming that the coordinates of the center of a projected circle calculated from the scatter-corrected image are (800, 500), in the bright-field image, the measured I 0 is 10000. In the scatter-corrected image, the I 3 is 5000, then the formula (4 )have to The D 1 of the (800, 500) position obtained in the attenuation projection image is 2000, and the D 2 of the (800, 500) position obtained from the projection image set is 3000, then the (800, 500) position can be obtained by formula (6) The scattered ray intensity Then the distribution of scatter values is obtained.
上述CT系统的散射校正方法及CT系统中的探测器采用面阵探测器。The scattering correction method of the above CT system and the detector in the CT system adopt an area array detector.
上述CT系统的散射校正方法及CT系统中,通过将散射校正器置于被扫描物体与探测器之间来消除散射的影响,大大地减少了扫描时间和处理的数据量,有效地提高了效率和精度。In the scatter correction method of the above-mentioned CT system and in the CT system, the influence of scatter is eliminated by placing the scatter corrector between the scanned object and the detector, which greatly reduces the scanning time and the amount of data processed, and effectively improves the efficiency and precision.
上述CT系统的散射校正方法及CT系统中的散射校正器结构简单,制造成本低廉,易于实现并适用于被扫描物体性质变化非常较的环境。The scatter correction method for the CT system and the scatter corrector in the CT system are simple in structure, low in manufacturing cost, easy to implement, and suitable for environments where the properties of scanned objects vary greatly.
以上所述实施例仅表达了本发明的几种实施方式,其描述较为具体和详细,但并不能因此而理解为对本发明专利范围的限制。应当指出的是,对于本领域的普通技术人员来说,在不脱离本发明构思的前提下,还可以做出若干变形和改进,这些都属于本发明的保护范围。因此,本发明专利的保护范围应以所附权利要求为准。The above-mentioned embodiments only express several implementation modes of the present invention, and the description thereof is relatively specific and detailed, but should not be construed as limiting the patent scope of the present invention. It should be pointed out that those skilled in the art can make several modifications and improvements without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent for the present invention should be based on the appended claims.
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