CN101982195A - Medicine for treating rheumatoid arthritis pain and preparation method thereof - Google Patents
Medicine for treating rheumatoid arthritis pain and preparation method thereof Download PDFInfo
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- CN101982195A CN101982195A CN2010105225198A CN201010522519A CN101982195A CN 101982195 A CN101982195 A CN 101982195A CN 2010105225198 A CN2010105225198 A CN 2010105225198A CN 201010522519 A CN201010522519 A CN 201010522519A CN 101982195 A CN101982195 A CN 101982195A
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- 239000003814 drug Substances 0.000 title claims abstract description 26
- 206010039073 rheumatoid arthritis Diseases 0.000 title claims abstract description 22
- 208000002193 Pain Diseases 0.000 title claims abstract description 19
- 230000036407 pain Effects 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 229940079593 drug Drugs 0.000 title description 6
- 239000002994 raw material Substances 0.000 claims abstract description 9
- 238000010438 heat treatment Methods 0.000 claims abstract description 7
- 239000007788 liquid Substances 0.000 claims abstract description 5
- 238000007789 sealing Methods 0.000 claims abstract description 5
- 241001093951 Ailanthus altissima Species 0.000 claims abstract description 4
- 239000004863 Frankincense Substances 0.000 claims abstract description 4
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 4
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 4
- 210000000582 semen Anatomy 0.000 claims abstract description 4
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- 239000009636 Huang Qi Substances 0.000 claims description 3
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- 239000009670 cang er zi wan Substances 0.000 claims description 3
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 claims description 3
- 238000005516 engineering process Methods 0.000 claims description 2
- 208000024891 symptom Diseases 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 7
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 241000427159 Achyranthes Species 0.000 abstract 1
- 244000144730 Amygdalus persica Species 0.000 abstract 1
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 235000017965 Asarum canadense Nutrition 0.000 abstract 1
- 235000003717 Boswellia sacra Nutrition 0.000 abstract 1
- 240000007551 Boswellia serrata Species 0.000 abstract 1
- 235000012035 Boswellia serrata Nutrition 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 240000007311 Commiphora myrrha Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- 235000000385 Costus speciosus Nutrition 0.000 abstract 1
- 240000009138 Curcuma zedoaria Species 0.000 abstract 1
- 235000003405 Curcuma zedoaria Nutrition 0.000 abstract 1
- 235000007162 Ferula assa foetida Nutrition 0.000 abstract 1
- 244000228957 Ferula foetida Species 0.000 abstract 1
- 235000012850 Ferula foetida Nutrition 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 241000212322 Levisticum officinale Species 0.000 abstract 1
- 241000195954 Lycopodium clavatum Species 0.000 abstract 1
- 241001676573 Minium Species 0.000 abstract 1
- 240000000249 Morus alba Species 0.000 abstract 1
- 235000008708 Morus alba Nutrition 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
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- 241000606265 Valeriana jatamansi Species 0.000 abstract 1
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- 235000019507 asafoetida Nutrition 0.000 abstract 1
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- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
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- 239000008159 sesame oil Substances 0.000 abstract 1
- 235000011803 sesame oil Nutrition 0.000 abstract 1
- 235000019509 white turmeric Nutrition 0.000 abstract 1
- 208000006820 Arthralgia Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
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- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
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- 206010034464 Periarthritis Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
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- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
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- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a medicine for treating rheumatoid arthritis pain, which comprises the following raw materials of ailanthus twig, willow twig, mulberry twig, elm twig, peach twig, dahurian angelicaroot, angelica, red peony root, radix scrophularia, dried rehmannia root, cassia, rhubarb, semen momordicae, frankincense, myrrh, Chinese asafoetida, liquorice, rhizoma curcumae longae, rehmanniae vaporata, Szechuan lovage rhizome, radix angelicae pubescentis, achyranthes root, cortex acanthopanacis, garden burnet root, trogopterus dung, zedoary, manchurian wildginger, pinellia tuber, siberian cocklour fruit, notoginseng, common clubmoss herb, raidx astragali, divaricate saposhnikovia root and minium. The preparation method comprises the following steps: adding 5000g of sesame oil to a pot for heating to 40 DEG C; sequentially adding the raw materials to the pot for heating to 100 DEG C and keeping the temperature for 30 minutes; filtering out dregs; adding the obtained liquid medicine to the pot for heating to 100 DEG C and keeping the temperature for 30 minutes; concentrating to obtain paste; canning and sealing after being cooled; and storing in a crypt for 30 days for use. The invention has the advantages of simple preparation process, convenient use, good treatment effect, addressing both the symptoms and root causes, no side effect, low cost, short treatment course and certain efficacy on treating rheumatoid arthritis pain.
Description
Technical field the invention belongs to technical field of pharmaceuticals, is specifically related to a kind of medicine for the treatment of rheumatoid arthritis pain and preparation method thereof.
The background technology rheumatoid arthritis be a kind of be the chronic systemic autoimmune disease of feature with the articular synovitis.Synovitis is outbreak repeatedly lastingly, the destruction that can cause intraarticular cartilage and bone, and joint function disturbance, in addition maimed.The vasculitis pathological changes is involved each organ of whole body, so primary disease is called rheumatoid disease again.Rheumatoid arthritis is a kind of inflammatory autoimmune disease of chronic, general, can cause multi-section position pain such as joint, cervical vertebra.The main whole body joint everywhere of invading is multiple, symmetry, chronic, hyperplastica synovitis, causes joint capsule and cartilage destruction, bone erosion then, causes joint deformity, and these are these sick characteristics.It has multiple morbidity form, and the symptom of every kind of morbidity form is also different.The rheumatoid arthritis treatment of pain mainly is Drug therapy at present, and as Salicylate: aspirin still is the choice drug of treatment rheumatoid arthritis; Indometacin: nonsteroid anti-inflammatory drugs, effect is better, its analgesia, bring down a fever and antiinflammatory action all stronger; The left Teng moxibustion of Japan's import, left Teng moxibustion price on the net is 450 yuan one course of treatment, treatment rheumatoid arthritis effect is very remarkable.But these medicines mostly are Western medicine greatly, and side effect is big, expense is high, the course of treatment is long.
Medicine of the treatment rheumatoid arthritis pain that summary of the invention the purpose of this invention is to provide a kind for the treatment of both the principal and secondary aspects of a disease, has no side effect, expense is low and preparation method thereof solves prior art and has the technical problem that side effect is big, expense is high, the course of treatment is long.
Solution of the present invention is based on pathogeny and understanding and the Therapeutic Principle of motherland's medical science to rheumatoid arthritis, with reference to ancient, modern pharmacological research achievement, filters out from motherland's medical treasure-house the effective medicine of rheumatoid arthritis pain therapy.
Medicine of the present invention is made by following raw material medicaments:
Ailanthus altissima (mill.) swingle branch 100g, Ramulus Salicis Babylonicae 100g, Ramulus Mori 100g, Ramulus ulmi pumilae 100g, Ramulus Persicae 100g, Radix Angelicae Dahuricae 100g, Radix Angelicae Sinensis 100g, Radix Paeoniae Rubra 100g, Radix Scrophulariae 100g, Radix Rehmanniae 100g, Cortex Cinnamomi 100g, Radix Et Rhizoma Rhei 100g, Semen Momordicae 100g, Olibanum 15g, Myrrha 10g, Resina Ferulae 10g, Radix Glycyrrhizae 10g, Rhizoma Curcumae Longae 10g, Radix Rehmanniae Preparata 10g, Rhizoma Chuanxiong 20g, Radix Angelicae Pubescentis 20g, Radix Achyranthis Bidentatae 20g, Cortex Acanthopancis 20g, Radix Sanguisorbae 20g, Oletum Trogopterori 20g, Rhizoma Curcumae 20g, Herba Asari 20g, Rhizoma Pinelliae 60g, Fructus Xanthii 30g, Radix Notoginseng 30g, Herba Lycopodii 40g, Radix Astragali 40g, Radix Saposhnikoviae 40g, Plumbum preparatium 1000g;
The preparation method that above-mentioned each component is made medicine of the present invention is:
Get Oleum sesami 5000g in pot, be heated to 40 ℃, again the above-mentioned raw materials medicine is sequentially added into pot internal heating to 100 ℃, be incubated 30 minutes, elimination medicinal residues, taking liquid reheat to 100 ℃ in pot is incubated 30 minutes, be condensed into cream, cooling back tinning sealing, in crypt store 30 days standby.
Medicine of the present invention is named and is " ZHUIFENG GAO ".
The clinical use result of medicine of the present invention " ZHUIFENG GAO " shows that following advantage is arranged:
1, painful area is local uses, and has rapid antiinflammatory, analgesic effect;
2, effective ingredient of the present invention scatter and disappear little, the curative effect height, have treating both the principal and secondary aspects of a disease, have no side effect, expense is low, short treating period, to the effective characteristics of treatment rheumatoid arthritis pain.
For showing the curative effect of medicine of the present invention " ZHUIFENG GAO ", case is selected in the clinical observation of the present invention surplus ten year, pasted in 7 days 1, nearly 1000 examples of treatment patient, the state of an illness be clearly better or pain relief for effectively, total effective rate is 98%.
Using method: during use, " ZHUIFENG GAO " is coated on the textile cloth, that is painful to paste that.
Model case is as follows:
1, Liu XX, the man, 45 years old, Clinical Laboratory was a rheumatoid arthritis, causes the gonalgia.With the present invention " ZHUIFENG GAO ", treat 35 days pain symptoms and disappear.
2, public XX, the man, 48 years old, Clinical Laboratory was a rheumatoid arthritis, caused knee joint and cervical vertebra ache.With the present invention " ZHUIFENG GAO ", treat 28 days pain symptoms and disappear.
3, king XX, the man, 40 years old, Clinical Laboratory was a rheumatoid arthritis, caused the gonalgia and scapulohumeral periarthritis disease.With the present invention " ZHUIFENG GAO ", treat 42 days pain symptoms and disappear.
4, king XX, the man, 45 years old, Clinical Laboratory was a rheumatoid arthritis, caused the gonalgia and prolapse of lumbar intervertebral disc.With the present invention " ZHUIFENG GAO ", treat 63 days pain symptoms and disappear.
5, Song XX, the man, 50 years old, Clinical Laboratory was a rheumatoid arthritis, caused arthralgia and prolapse of lumbar intervertebral disc.With the present invention " ZHUIFENG GAO ", treat 70 days pain symptoms and disappear.
6, Liu XX, the man, 40 years old, Clinical Laboratory was a rheumatoid arthritis, caused arthralgia and prolapse of lumbar intervertebral disc and bone matrix hyperplasia.With the present invention " ZHUIFENG GAO ", treat 140 days pain symptoms and disappear.
The specific embodiment
Press following proportioning weighting raw materials:
Ailanthus altissima (mill.) swingle branch 100g, Ramulus Salicis Babylonicae 100g, Ramulus Mori 100g, Ramulus ulmi pumilae 100g, Ramulus Persicae 100g, Radix Angelicae Dahuricae 100g, Radix Angelicae Sinensis 100g, Radix Paeoniae Rubra 100g, Radix Scrophulariae 100g, Radix Rehmanniae 100g, Cortex Cinnamomi 100g, Radix Et Rhizoma Rhei 100g, Semen Momordicae 100g, Olibanum 15g, Myrrha 10g, Resina Ferulae 10g, Radix Glycyrrhizae 10g, Rhizoma Curcumae Longae 10g, Radix Rehmanniae Preparata 10g, Rhizoma Chuanxiong 20g, Radix Angelicae Pubescentis 20g, Radix Achyranthis Bidentatae 20g, Cortex Acanthopancis 20g, Radix Sanguisorbae 20g, Oletum Trogopterori 20g, Rhizoma Curcumae 20g, Herba Asari 20g, Rhizoma Pinelliae 60g, Fructus Xanthii 30g, Radix Notoginseng 30g, Herba Lycopodii 40g, Radix Astragali 40g, Radix Saposhnikoviae 40g, Plumbum preparatium 1000g;
The preparation method that above-mentioned each component is made medicine of the present invention is:
Get Oleum sesami 5000g in pot, be heated to 40 ℃, again the above-mentioned raw materials medicine is sequentially added into pot internal heating to 100 ℃, be incubated 30 minutes, elimination medicinal residues, taking liquid reheat to 100 ℃ in pot is incubated 30 minutes, be condensed into cream, cooling back tinning sealing, in crypt store 30 days standby.
Use medicine of the present invention " ZHUIFENG GAO " points for attention:
Avoid: seafood.
Claims (2)
1. medicine for the treatment of rheumatoid arthritis pain is characterized in that it is made by following raw material medicaments: ailanthus altissima (mill.) swingle branch 100g, Ramulus Salicis Babylonicae 100g, Ramulus Mori 100g, Ramulus ulmi pumilae 100g, Ramulus Persicae 100g, Radix Angelicae Dahuricae 100g, Radix Angelicae Sinensis 100g, Radix Paeoniae Rubra 100g, Radix Scrophulariae 100g, Radix Rehmanniae 100g, Cortex Cinnamomi 100g, Radix Et Rhizoma Rhei 100g, Semen Momordicae 100g, Olibanum 15g, Myrrha 10g, Resina Ferulae 10g, Radix Glycyrrhizae 10g, Rhizoma Curcumae Longae 10g, Radix Rehmanniae Preparata 10g, Rhizoma Chuanxiong 20g, Radix Angelicae Pubescentis 20g, Radix Achyranthis Bidentatae 20g, Cortex Acanthopancis 20g, Radix Sanguisorbae 20g, Oletum Trogopterori 20g, Rhizoma Curcumae 20g, Herba Asari 20g, Rhizoma Pinelliae 60g, Fructus Xanthii 30g, Radix Notoginseng 30g, Herba Lycopodii 40g, Radix Astragali 40g, Radix Saposhnikoviae 40g, Plumbum preparatium 1000g; During preparation, get Oleum sesami 5000g in pot, be heated to 40 ℃, again the above-mentioned raw materials medicine is sequentially added into pot internal heating to 100 ℃, be incubated 30 minutes, elimination medicinal residues, taking liquid reheat to 100 ℃ in pot is incubated 30 minutes, be condensed into cream, cooling back tinning sealing, in crypt store 30 days standby.
2. the preparation method of the medicine of treatment rheumatoid arthritis pain according to claim 1, it is characterized in that finishing: get Oleum sesami 5000g in pot by following technology, be heated to 40 ℃, again the above-mentioned raw materials medicine be sequentially added into pot internal heating to 100 ℃, be incubated 30 minutes, the elimination medicinal residues, taking liquid reheat to 100 ℃ in pot is incubated 30 minutes, is condensed into cream, the tinning sealing of cooling back, in crypt store 30 days standby.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201010522519A CN101982195B (en) | 2010-10-28 | 2010-10-28 | Medicine for treating rheumatoid arthritis pain and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201010522519A CN101982195B (en) | 2010-10-28 | 2010-10-28 | Medicine for treating rheumatoid arthritis pain and preparation method thereof |
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| Publication Number | Publication Date |
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| CN101982195A true CN101982195A (en) | 2011-03-02 |
| CN101982195B CN101982195B (en) | 2011-12-07 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074833A (en) * | 2016-06-21 | 2016-11-09 | 刘晓东 | The medicine of the pathological changes that treatment is caused by rheumatism and preparation method |
| CN114642638A (en) * | 2022-05-10 | 2022-06-21 | 徐州三农生物科技有限公司 | A medicated compress agent for the treatment of rheumatic arthritis |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101002901A (en) * | 2007-01-05 | 2007-07-25 | 梁进 | Plaster for dispelling wind and removing dampness |
| CN101317996A (en) * | 2007-01-20 | 2008-12-10 | 徐长山 | Traditional Chinese medicine emplastrum for rheumatism of muscles and bones |
| CN101675981A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Paste agent for treating low back pain |
-
2010
- 2010-10-28 CN CN201010522519A patent/CN101982195B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101002901A (en) * | 2007-01-05 | 2007-07-25 | 梁进 | Plaster for dispelling wind and removing dampness |
| CN101317996A (en) * | 2007-01-20 | 2008-12-10 | 徐长山 | Traditional Chinese medicine emplastrum for rheumatism of muscles and bones |
| CN101675981A (en) * | 2008-09-18 | 2010-03-24 | 天津市中宝制药有限公司 | Paste agent for treating low back pain |
Non-Patent Citations (1)
| Title |
|---|
| 《上海中医药杂志》 20021231 陈丽云 外用黑膏药的临床研究概况 , 第06期 2 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074833A (en) * | 2016-06-21 | 2016-11-09 | 刘晓东 | The medicine of the pathological changes that treatment is caused by rheumatism and preparation method |
| CN114642638A (en) * | 2022-05-10 | 2022-06-21 | 徐州三农生物科技有限公司 | A medicated compress agent for the treatment of rheumatic arthritis |
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| CN101982195B (en) | 2011-12-07 |
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