CN101979045B - 一种治疗咳喘病的药物 - Google Patents
一种治疗咳喘病的药物 Download PDFInfo
- Publication number
- CN101979045B CN101979045B CN2010105225785A CN201010522578A CN101979045B CN 101979045 B CN101979045 B CN 101979045B CN 2010105225785 A CN2010105225785 A CN 2010105225785A CN 201010522578 A CN201010522578 A CN 201010522578A CN 101979045 B CN101979045 B CN 101979045B
- Authority
- CN
- China
- Prior art keywords
- medicament
- cough
- minutes
- raw material
- boiling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 35
- 206010011224 Cough Diseases 0.000 title claims abstract description 17
- 208000006673 asthma Diseases 0.000 title abstract description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract description 6
- 238000009835 boiling Methods 0.000 claims abstract description 5
- 239000002994 raw material Substances 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 5
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 claims abstract description 4
- 239000000706 filtrate Substances 0.000 claims abstract description 4
- 229940079593 drug Drugs 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 6
- 210000000582 semen Anatomy 0.000 claims description 6
- 241000628997 Flos Species 0.000 claims description 3
- 239000012467 final product Substances 0.000 claims description 3
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 3
- 240000001970 Raphanus sativus var. sativus Species 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 6
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 208000024891 symptom Diseases 0.000 abstract description 2
- 238000001914 filtration Methods 0.000 abstract 2
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241000758794 Asarum Species 0.000 abstract 1
- 235000013717 Houttuynia Nutrition 0.000 abstract 1
- 240000000691 Houttuynia cordata Species 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 241000234435 Lilium Species 0.000 abstract 1
- 241000245050 Menispermum Species 0.000 abstract 1
- 235000004347 Perilla Nutrition 0.000 abstract 1
- 244000124853 Perilla frutescens Species 0.000 abstract 1
- 235000006751 Platycodon Nutrition 0.000 abstract 1
- 244000274050 Platycodon grandiflorum Species 0.000 abstract 1
- 244000018633 Prunus armeniaca Species 0.000 abstract 1
- 235000009827 Prunus armeniaca Nutrition 0.000 abstract 1
- 244000088415 Raphanus sativus Species 0.000 abstract 1
- 235000021282 Sterculia Nutrition 0.000 abstract 1
- 240000001058 Sterculia urens Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 229930189914 platycodon Natural products 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 229940059107 sterculia Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 4
- 229940124599 anti-inflammatory drug Drugs 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 206010036790 Productive cough Diseases 0.000 description 3
- 230000001088 anti-asthma Effects 0.000 description 3
- 239000000924 antiasthmatic agent Substances 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- XWTYSIMOBUGWOL-UHFFFAOYSA-N (+-)-Terbutaline Chemical compound CC(C)(C)NCC(O)C1=CC(O)=CC(O)=C1 XWTYSIMOBUGWOL-UHFFFAOYSA-N 0.000 description 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 2
- 206010006458 Bronchitis chronic Diseases 0.000 description 2
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 2
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 2
- 241000220259 Raphanus Species 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 2
- 230000000954 anitussive effect Effects 0.000 description 2
- 229940124584 antitussives Drugs 0.000 description 2
- 206010006451 bronchitis Diseases 0.000 description 2
- 239000000812 cholinergic antagonist Substances 0.000 description 2
- 208000007451 chronic bronchitis Diseases 0.000 description 2
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 description 2
- 229960002052 salbutamol Drugs 0.000 description 2
- 230000002048 spasmolytic effect Effects 0.000 description 2
- 229960000195 terbutaline Drugs 0.000 description 2
- CFJMRBQWBDQYMK-UHFFFAOYSA-N 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester Chemical compound C=1C=CC=CC=1C1(C(=O)OCCOCCN(CC)CC)CCCC1 CFJMRBQWBDQYMK-UHFFFAOYSA-N 0.000 description 1
- 229930186147 Cephalosporin Natural products 0.000 description 1
- 201000006306 Cor pulmonale Diseases 0.000 description 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 description 1
- 206010014561 Emphysema Diseases 0.000 description 1
- 208000004186 Pulmonary Heart Disease Diseases 0.000 description 1
- 229940126575 aminoglycoside Drugs 0.000 description 1
- FQPFAHBPWDRTLU-UHFFFAOYSA-N aminophylline Chemical compound NCCN.O=C1N(C)C(=O)N(C)C2=C1NC=N2.O=C1N(C)C(=O)N(C)C2=C1NC=N2 FQPFAHBPWDRTLU-UHFFFAOYSA-N 0.000 description 1
- 229960003556 aminophylline Drugs 0.000 description 1
- 235000019270 ammonium chloride Nutrition 0.000 description 1
- 229960001040 ammonium chloride Drugs 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000002924 anti-infective effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- OJGDCBLYJGHCIH-UHFFFAOYSA-N bromhexine Chemical compound C1CCCCC1N(C)CC1=CC(Br)=CC(Br)=C1N OJGDCBLYJGHCIH-UHFFFAOYSA-N 0.000 description 1
- 229960003870 bromhexine Drugs 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229940124587 cephalosporin Drugs 0.000 description 1
- 150000001780 cephalosporins Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 229940121657 clinical drug Drugs 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 229960003276 erythromycin Drugs 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 235000019371 penicillin G benzathine Nutrition 0.000 description 1
- 229940056360 penicillin g Drugs 0.000 description 1
- 229960003436 pentoxyverine Drugs 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 description 1
- 229960004618 prednisone Drugs 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 150000007660 quinolones Chemical class 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗咳喘病的药物，以百合、苏子、鱼腥草、杏仁、萝卜籽、金银花、北豆根、桔梗、蒲公英、甘草、胖大海、马兜铃为原料；将上述诸药放入砂锅内，按原料药总质量的1∶2加水，文火煎煮，沸后20分钟，将药液滤出，再按原料药总质量的1∶1加水文火煎煮，沸后20分钟，将药液滤出，合并两次滤液装瓶即可。本发明药物临床使用结果表明，具有迅速消炎、止咳喘的作用；具有标本兼治、无副作用、费用低、对治疗咳喘病有治愈的特点，总有效率为96％。
Description
技术领域 本发明属于药物技术领域，具体涉及一种治疗咳喘病的药物。
背景技术 咳喘病属现代医学的慢性支气管炎、支气管哮喘、肺气肿、肺心病及其他肺部疾患范畴。多发生于冬春季节，气候寒冷或气候变更时，易反复发作，日久则正气渐衰，而“宿根”愈盛，缠绵难愈。针对慢支的病因、病期和反复发作的特点，目前，主要采取防治结合的综合措施。在急性发作期和慢性迁延期应以控制感染和祛痰、镇咳为主。伴发喘息时，应予解痉平喘的治疗；对临床缓解期宜加强锻炼，增强体质，提高机体抵抗力，预防复发为主。急性发作期的治疗，轻者可口服，较重病人用肌注或静脉滴注抗生素，常用的有青霉素G、红霉素、氨基甙类、喹诺酮类、头孢菌素类抗生素等，在抗感染治疗的同时，应用祛痰、镇咳药物，以改善症状；迁延期病人常用药物有氯化铵合剂、溴已新、维静宁等，对老年体弱无力咳痰者或痰量较多者，应以祛痰为主，协助排痰，畅通呼吸道，解痉、平喘，常选用氨茶碱、特布他林(terbutaline)等口服或用沙丁胺醇(salbutamol)等吸入剂，若气道舒张剂使用后气道仍有持续阻塞，可使用皮质激素，泼尼松20-40mg/d。但是，这些药物大多为西药，副作用大、费用高。
发明内容 本发明的目的是提供一种标本兼治、无副作用、费用低的治疗咳喘病的药物，解决现有技术存在副作用大、费用高的技术问题。
本发明的解决方案是基于祖国医学对咳喘病的发病机理和认识及治疗原则，参考古、今药理研究成就，从祖国医学宝库中筛选出对咳喘病治疗有特效的药物。
本发明药物是由下述原料药制成的：
百合12g、苏子10g、鱼腥草12g、杏仁6g、萝卜籽6g、金银花20g、北豆根10g、桔梗10g、蒲公英15g、甘草6g、胖大海3g、马兜铃1g；将上述诸药放入砂锅内，按原料药总质量的1∶2加水，文火煎煮，沸后20分钟，将药液滤出，再按原料药总质量的1∶1加水文火煎煮，沸后20分钟，将药液滤出，合并两次滤液装瓶即可。
本发明药物临床使用结果表明，具有迅速消炎、止咳喘的作用；具有标本兼治、无副作用、费用低、对治疗咳喘病有治愈的特点。
为表明本发明药物的疗效，本发明经十余年的临床观察选择病例，每日早晚口服2次，每次50ml，治疗病人近1000例，病情明显好转或治愈为有效，总有效率为96％。
典型病例如下：
1、孙XX，男，35岁，咳喘半年，平时口服消炎药，效果不明显，用本发明药物，治疗15天症状消失。
2、公XX，男，50岁，咳喘一年，平时口服消炎药、平喘药，效果不明显，用本发明药物，治疗30天症状消失。
3、王XX，男，60岁，咳喘一年，平时口服消炎药、平喘药，效果不明显，用本发明药物，治疗60天症状消失。
4、王XX，男，75岁，咳喘二年余，平时口服消炎药、平喘药、注射抗生素，效果不明显，用本发明药物，治疗60天症状消失。
具体实施方式 取百合12g、苏子10g、鱼腥草12g、杏仁6g、萝卜籽6g、金银花20g、北豆根10g、桔梗10g、蒲公英15g、甘草6g、胖大海3g 马兜铃1g；将上述诸药放入砂锅内，按原料药总质量的1∶2加水，文火煎煮，沸后20分钟，将药液滤出，再按原料药总质量的1∶1加水文火煎煮，沸后20分钟，将药液滤出，合并两次滤液装瓶即可。
Claims (1)
1.一种治疗咳喘病的药物，其特征在于它是由下述原料药制成的：百合12g、苏子10g、鱼腥草12g、杏仁6g、萝卜籽6g、金银花20g、北豆根10g、桔梗10g、蒲公英15g、甘草6g、胖大海3g、马兜铃1g；将上述诸药放入砂锅内，按原料药总质量的1∶2加水，文火煎煮，沸后20分钟，将药液滤出，再按原料药总质量的1∶1加水文火煎煮，沸后20分钟，将药液滤出，合并两次滤液装瓶即可。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105225785A CN101979045B (zh) | 2010-10-28 | 2010-10-28 | 一种治疗咳喘病的药物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105225785A CN101979045B (zh) | 2010-10-28 | 2010-10-28 | 一种治疗咳喘病的药物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101979045A CN101979045A (zh) | 2011-02-23 |
| CN101979045B true CN101979045B (zh) | 2011-10-05 |
Family
ID=43599600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105225785A Expired - Fee Related CN101979045B (zh) | 2010-10-28 | 2010-10-28 | 一种治疗咳喘病的药物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101979045B (zh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102284022A (zh) * | 2011-09-15 | 2011-12-21 | 徐弋舒 | 一种止咳药物及其制备方法 |
| CN103766751B (zh) * | 2014-01-24 | 2016-02-03 | 赵杏珍 | 防治雾霾引发的呼吸道疾病及肺癌的药食同膳面 |
| CN104306908A (zh) * | 2014-03-24 | 2015-01-28 | 河南茗轩食品科技有限公司 | 用于预防雾霾所致呼吸系统疾病的保健组合物及其制备方法 |
| CN104173711A (zh) * | 2014-08-07 | 2014-12-03 | 韦江南 | 一种治疗哮喘病的中药 |
| CN104491378A (zh) * | 2014-12-18 | 2015-04-08 | 李大刚 | 制备治疗支气管哮喘药物的方法 |
| CN108641864A (zh) * | 2015-07-20 | 2018-10-12 | 广元市立柱天中药研究所 | 一种清肺饮品 |
| CN105169109A (zh) * | 2015-10-27 | 2015-12-23 | 贵州苗生药业有限公司 | 化痰止咳、平喘的中药制剂 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1544071A (zh) * | 2003-05-21 | 2004-11-10 | 西安碑林药业股份有限公司 | 一种治疗小儿咳喘的中药及其制备方法 |
-
2010
- 2010-10-28 CN CN2010105225785A patent/CN101979045B/zh not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1544071A (zh) * | 2003-05-21 | 2004-11-10 | 西安碑林药业股份有限公司 | 一种治疗小儿咳喘的中药及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101979045A (zh) | 2011-02-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101979045B (zh) | 一种治疗咳喘病的药物 | |
| CN101380436B (zh) | 一种治疗急慢性咽炎的中药 | |
| CN101143176A (zh) | 治疗肺炎的中药 | |
| CN101954062A (zh) | 一种治疗慢性咽炎的药物 | |
| CN101653529A (zh) | 一种用于治疗变态反应性鼻炎的药物 | |
| CN102614286A (zh) | 一种治疗风寒感冒的药物及其制备方法 | |
| CN101164611A (zh) | 治疗寒邪束肺型百日咳的中药 | |
| CN101152252A (zh) | 治疗慢性鼻炎的中药 | |
| CN101138613A (zh) | 治疗小儿急性支气管炎的中药 | |
| CN101912596A (zh) | 一种治疗过敏性鼻炎的药物及其制备方法 | |
| CN101954061B (zh) | 一种治疗慢性喉头炎的药物 | |
| CN101757160A (zh) | 止痒汤 | |
| CN103169855A (zh) | 一种治疗慢性心衰的药物组合物 | |
| CN101143199A (zh) | 治疗慢性支气管炎的中药 | |
| CN101336990B (zh) | 一种治疗胆囊炎的药物 | |
| CN103550504A (zh) | 一种治疗慢性鼻炎的中药组合物 | |
| CN103494939A (zh) | 一种治疗老年习惯性便秘的中药 | |
| CN103316235B (zh) | 一种治疗哮喘的中药及其制备方法 | |
| CN108704064A (zh) | 一种治疗艾滋病的中药组合物和制备方法 | |
| CN102366606B (zh) | 雾化平喘液及其制作方法 | |
| CN101972458A (zh) | 一种治疗慢性鼻窦炎的药物 | |
| CN101143188A (zh) | 治疗慢性喘息型支气管炎的中药 | |
| CN101502597A (zh) | 一种用于治疗胃痛的药物及其制备方法 | |
| CN105147971A (zh) | 一种治疗小儿化脓性扁桃体炎的中药制剂 | |
| CN102688406B (zh) | 治疗咳嗽的鱼腥草中药汤剂及制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: NANTONG ORIENT INDUSTRY CO., LTD. Free format text: FORMER OWNER: LI GUIBIN Effective date: 20141203 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Yang Jing Inventor before: Li Guibin Inventor before: Li Xiaolong Inventor before: Wang Yuezhang |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 276200 LINYI, SHANDONG PROVINCE TO: 226000 NANTONG, JIANGSU PROVINCE Free format text: CORRECT: INVENTOR; FROM: LI GUIBIN LI XIAOLONG WANG YUEZHANG TO: YANG JING |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20141203 Address after: Gangzha District of Jiangsu city of Nantong province Changtai 226000 Road on the eastern side of Jian Gou Village 9 group 1. Patentee after: Nantong City Dongfang Plastic Co., Ltd. Address before: 276200, Shandong, Linyi province Mengyin County wild town shop village Patentee before: Li Guibin |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20111005 Termination date: 20181028 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |