A kind of Chinese medicine oral liquid of treating cholecystitis gallstones and preparation method thereof
(1) technical field
The present invention relates to a kind of Chinese medicine oral liquid, particularly a kind of Chinese medicine oral liquid of treating cholecystitis gallstones and preparation method thereof.
(2) background technology
Cholecystitis, cholelithiasis are current commonly encountered diseases and frequently-occurring diseases, and the traditional Chinese medical science thinks that cholecystitis, cholelithiasis belong to categories such as " hypochondriac pain ", " jaundice "; Be because of feelings will not smooth, the depression of liver-QI that the greasy grade of surfeit delicious food causes, dysfunction of the spleen in transportation; Give birth in damp and hot, heat is fried in shallow oil bile, condenses into stone; Stone resistance biliary tract is satisfied and is given birth to all diseases.Cholecystitis, two kinds of pathological changes of cholelithiasis are often followed generation, the symptom of gastral cavilty portion pain occurs, obscure mutually with gastropathy easily, if pressing gastrotherapy then must not its effect.Along with popularizing of B ultrasonic, the diagnosis of cholecystitis, cholelithiasis is quite easy, and for the patient of frequent gastric abscess, as long as do B ultrasonic, majority can be made a definite diagnosis.Along with growth in the living standard; Because the not science of people's diet, living habit; The sickness rate of cholecystitis, cholelithiasis is rising gradually, and factors such as high sugar, hypercholesterolemia, high fat diet, gallbladder biliary tract infection, biliary tract parasite, obesity, heredity all possibly brought out cholelithiasis.Violent pain usually makes the patient suffering can't bear, and also possibly cause dangerous complication such as acute cholecystitis, cholangitis, acute pancreatitis, tumor of gallbladder, and this disease is extremely difficult thoroughly cures, and relapse rate is high.Suffering from cholecystitis, cholelithiasis is mainly caused by following several kinds of factors:
(1) calculus factor: about 10% chronic cholecystitis factor thus causes, reason is that calculus stimulates gallbladder wall to be inflamed, but secondary bacterial infection also;
(2) dyskinesia: dyskinesia can develop into organic disease gradually, and after vagectomy, variation appears in the tension force of gallbladder and power; Emptying time prolongs; Gallbladder increases, and occurs the gallbladder wall fibrosis gradually and thickens the infiltration of companion's chronic inflammatory cell;
(3) infect: 1/3 patient's biliary culture has bacterial growth, and antibacterial makes contiguous histoorgan inflammation direct extension through blood or lymph, or goes upward to gallbladder through the vater's papilla opening and infect.Chronic cholecystitis also can be caused that 15% chronic cholecystitis patient had history of virus hepatitis in the past by viral infection, and fungus, parasite such as ascarid, Giardia intestinalis infect and also can cause chronic cholecystitis;
(4) metabolic factor: in gallbladder, inject some cholate solution and can cause chronic cholecystitis, this is relevant with the chemical action that the bile acid composition changes, and pancreatic juice backflows and also can cause the chemical chronic cholecystitis;
(5) vascular factor: the gallbladder wall vascular lesion can cause the mucous membrane of gallbladder infringement, and gallbladder concentrating function and elastic force subtract mistake, fibrosis occurs;
(6) acute cholecystitis delay.
Western medical treatment cholecystitis, cholelithiasis are cured the symptoms, not the disease, and the operative treatment contraindication is many, wound heavy, misery is big, cost is many, complication many and certain danger is arranged, and the post-operative recovery time is long.This disease chronic disease time is long, and difficult radical cure is prone to recurrence.Doctor trained in Western medicine is cured the symptoms, not the disease, and the traditional Chinese medical science is effected a permanent cure, though Chinese herbs decoction can overcome above-mentioned shortcoming, it is time-consuming to decoct the process trouble, and travelling is carried also inconvenient.
(3) summary of the invention
The present invention is in order to remedy the deficiency of prior art, a kind of evident in efficacy, taking convenience is provided, has been specifically designed to Chinese medicine oral liquid of treatment cholecystitis gallstones and preparation method thereof.
The present invention realizes through following technical scheme:
A kind of Chinese medicine oral liquid of treating cholecystitis gallstones, its special character is: the component by following parts by weight is processed:
Rhizoma Coptidis (processed with wine) 20-30 part Radix Scutellariae (processed with wine) 20-30 part Radix et Rhizoma Rhei (stir-fried with wine) 20-40 part
Flos Lonicerae 20-40 part Herba Lysimachiae 50-70 part vinegar is fried Radix Curcumae 10-30 part
Radix Aucklandiae 10-20 part stir-baked Fructus Aurantii in bran 10-30 part Radix Bupleuri (processed with vinegar) 10-30 part
Vinegar Rhizoma Corydalis 20-40 part Radix Clematidis 50-70 part Fructus Amomi 5-15 part
Vinegar Endothelium Corneum Gigeriae Galli (parched) 10-25 part Fructus Crataegi (parched to brown) 20-40 part Fructus Mume 40-50 part
Spora Lygodii 20-40 part Radix Codonopsis 10-30 part Rhizoma Dioscoreae (parched with bran) 10-30 part
Honey Radix Astragali 10-30 part Pericarpium Zanthoxyli 5-20 part.
The present invention treats the Chinese medicine oral liquid of cholecystitis gallstones, and its preferred scheme is: the component by following parts by weight is processed:
30 parts of 25 parts of Radix et Rhizoma Rhei (stir-fried with wine) of 25 parts of Radix Scutellariae (processed with wine) of Rhizoma Coptidis (processed with wine)
60 portions of vinegar of 30 portions of Herba Lysimachiaes of Flos Lonicerae are fried 20 parts of Radix Curcumaes
20 parts of 20 parts of Radix Bupleuri (processed with vinegar) of 15 parts of stir-baked Fructus Aurantii in bran of the Radix Aucklandiae
10 parts of 60 parts of Fructus Amomis of 30 parts of Radix Clematidis of vinegar Rhizoma Corydalis
45 parts of 30 portions of Fructus Mumes of 15 parts of Fructus Crataegi (parched to brown)s of vinegar Endothelium Corneum Gigeriae Galli (parched)
20 parts of 20 parts of Rhizoma Dioscoreae (parched with bran) of 30 parts of Radix Codonopsis of Spora Lygodii
10 parts in 20 portions of Pericarpium Zanthoxylies of the honey Radix Astragali.
The method for making of said vinegar Endothelium Corneum Gigeriae Galli (parched) is: get clean Endothelium Corneum Gigeriae Galli, add vinegar and mix thoroughly, moistening is put in the pot to passing through, and takes out when frying to little heaving with slow fire, cools.Every Endothelium Corneum Gigeriae Galli 100 grams are with vinegar 10 grams.
The present invention treats the method for preparing of the Chinese medicine oral liquid of cholecystitis gallstones, comprises the steps:
(1) take by weighing each crude drug Rhizoma Coptidis (processed with wine), Radix Scutellariae (processed with wine), Radix et Rhizoma Rhei (stir-fried with wine), Flos Lonicerae, Herba Lysimachiae, vinegar stir-fry Radix Curcumae, the Radix Aucklandiae, stir-baked Fructus Aurantii in bran, Radix Bupleuri (processed with vinegar), vinegar Rhizoma Corydalis, Radix Clematidis, Fructus Amomi, vinegar Endothelium Corneum Gigeriae Galli (parched), Fructus Crataegi (parched to brown), Fructus Mume, Spora Lygodii, Radix Codonopsis, Rhizoma Dioscoreae (parched with bran), the sweet Radix Astragali, Pericarpium Zanthoxyli, subsequent use behind the decontamination;
(2) with the above-mentioned raw materials medicine mixing of said parts by weight, last pot steamed 30 minutes, dried in the shade;
(3) with 2500 milliliter 70% brewing grains white spirit bubble 14 days, get 30 milliliters of stock solutions then and be blended into 0.5 kilogram of pure water mixing, bottling promptly gets.
The present invention treats the Chinese medicine oral liquid of cholecystitis gallstones, and in order to obtain better therapeutic, component wherein also comprises Rhizoma Cyperi 20-40 part.
The present invention treats the Chinese medicine oral liquid of cholecystitis gallstones, and its preferred scheme is: the component by following parts by weight is processed:
30 parts of 25 parts of Radix et Rhizoma Rhei (stir-fried with wine) of 25 parts of Radix Scutellariae (processed with wine) of Rhizoma Coptidis (processed with wine)
60 portions of vinegar of 30 portions of Herba Lysimachiaes of Flos Lonicerae are fried 20 parts of Radix Curcumaes
20 parts of 20 parts of Radix Bupleuri (processed with vinegar) of 15 parts of stir-baked Fructus Aurantii in bran of the Radix Aucklandiae
10 parts of 60 parts of Fructus Amomis of 30 parts of Radix Clematidis of vinegar Rhizoma Corydalis
45 parts of 30 portions of Fructus Mumes of 15 parts of Fructus Crataegi (parched to brown)s of vinegar Endothelium Corneum Gigeriae Galli (parched)
20 parts of 20 parts of Rhizoma Dioscoreae (parched with bran) of 30 parts of Radix Codonopsis of Spora Lygodii
30 parts of 10 portions of Rhizoma Cyperis of honey 20 portions of Pericarpium Zanthoxylies of the Radix Astragali.
The present invention treats the method for preparing of the Chinese medicine oral liquid adding Rhizoma Cyperi of cholecystitis gallstones, comprises the steps:
(1) take by weighing each crude drug Rhizoma Coptidis (processed with wine), Radix Scutellariae (processed with wine), Radix et Rhizoma Rhei (stir-fried with wine), Flos Lonicerae, Herba Lysimachiae, vinegar stir-fry Radix Curcumae, the Radix Aucklandiae, stir-baked Fructus Aurantii in bran, Radix Bupleuri (processed with vinegar), vinegar Rhizoma Corydalis, Radix Clematidis, Fructus Amomi, vinegar Endothelium Corneum Gigeriae Galli (parched), Fructus Crataegi (parched to brown), Fructus Mume, Spora Lygodii, Radix Codonopsis, Rhizoma Dioscoreae (parched with bran), the sweet Radix Astragali, Pericarpium Zanthoxyli, Rhizoma Cyperi, subsequent use behind the decontamination;
(2) with the above-mentioned raw materials medicine mixing of said parts by weight, last pot steamed 30 minutes, dried in the shade;
(3) with 2500 milliliter 70% brewing grains white spirit bubble 14 days, get 30 milliliters of stock solutions then and be blended into 0.5 kilogram of pure water mixing, bottling promptly gets.
Instructions of taking: once a day, once obey 50 milliliters, obeyed 10 days for one bottle, morning, (medicine) being taken before meal usefulness was had a meal after 1 hour again.Because of being the chronic disease medication, 30 days is a course of treatment, and can cure general 1-6 course of treatment.Allow small amount of precipitate in the oral liquid, must fully shake up when taking medicine, otherwise affect the treatment.
Taboo: period in a medicine fasting maror, Chinese liquor and contain the Western medicine of one type of sulbactam.
Cholecystitis or/cause of disease of companion's cholelithiasis: when liver function was undesired, the hepatocyte bile secretion was under some influence, and the bile of gallbladder stores concentrating function and also can be affected, and causes cholecystitis; The patient with liver cirrhosis hypoimmunity; Infect easily; No matter whole body or local infection, pathogenic bacteria all can pass through approach such as blood, lymph, biliary tract, intestinal, the diffusion of adjacent organs inflammation invades, and parasitic intrusion and the antibacterial of bringing into thereof also are the major reasons that causes cholecystitis.And cholecystitis or cholelithiasis show as in the abnormal patient of part liver function that jaundice continues that difficulty is fallen or jaundice repeatedly and often with the symptom of cholecystitis.
The principle of treatment by Chinese herbs is to be main with " regulating the flow of QI to alleviate depression, clearing away heat-damp and promoting diuresis, Tongli are captured ", must catch the pathogenesis of liver and gall stasis, notes qi depression to blood stasis, damp and hot resistance, hepatopathy and the spleen hyperactive liver-QI attacking the stomach, or the wooden strongly fragrant merger of soil heap soil or fertilizer over and around the roots of accumulateing.Chinese medicine only relies on single medicinal material and looks after not comprehensively, so need multiple medicine proper fit, utilize mutual collaborative or resistant function, and raising curative effect and reduce untoward reaction reaches treating both the principal and secondary aspects of a disease.
Chinese medicine oral liquid of the present invention is specifically designed to treatment cholecystitis, cholelithiasis, changes or has relaxed the property of medicine through means such as compatibilities, and the medicine that nature and flavor are contained partially obtains relaxing, and depressed liver-energy dispersing and QI regulating, clearing away heat-damp and promoting diuresis, Tongli are captured, cholagogic and lithagogue; Clinical practice is evident in efficacy, and active ingredient absorbs many, and the property of medicine is bringd into play, treating both the principal and secondary aspects of a disease; Safe and reliable, the effect of giving full play to medicine does not injure Liver and kidney again, and mouthfeel is good; Taking convenience is beneficial to storage, and diabetes, hyperpietic can relievedly take.Treat 360 examples altogether, total effective rate reaches 98%.
(4) specific embodiment
Embodiment 1:
The method for preparing of the Chinese medicine oral liquid of treatment cholecystitis gallstones, adopt following steps:
(1) take by weighing Rhizoma Coptidis (processed with wine) 25 gram, Radix Scutellariae (processed with wine) 25 grams, Radix et Rhizoma Rhei (stir-fried with wine) 30 grams, Flos Lonicerae 30 grams, Herba Lysimachiae 60 grams, vinegar and fry Radix Curcumae 20 grams, the Radix Aucklandiae 15 grams, stir-baked Fructus Aurantii in bran 20 grams, Radix Bupleuri (processed with vinegar) 20 grams, vinegar Rhizoma Corydalis 30 grams, Radix Clematidis 60 grams, Fructus Amomi 10 grams, vinegar Endothelium Corneum Gigeriae Galli (parched) 15 grams, Fructus Crataegi (parched to brown) 30 grams, Fructus Mume 45 grams, Spora Lygodii 30 grams, Radix Codonopsis 20 grams, Rhizoma Dioscoreae (parched with bran) 20 grams, the sweet Radix Astragali 20 grams, Pericarpium Zanthoxyli 10 grams, subsequent use behind the decontamination;
(2) with above-mentioned raw materials medicine mixing, last pot steamed 30 minutes, dried in the shade;
(3) with 2500 milliliter 70% brewing grains white spirit bubble 14 days, get 30 milliliters of stock solutions then and be blended into 0.5 kilogram of pure water mixing, can take by 500 milliliters/bottled bottle.
Instructions of taking: once a day, once obey 50 milliliters, obeyed 10 days for one bottle, morning, (medicine) being taken before meal usefulness was had a meal after 1 hour again.Because of being the chronic disease medication, 30 days is a course of treatment, and can cure general 1-6 course of treatment.
Embodiment 2:
The method for preparing of the Chinese medicine oral liquid of this treatment cholecystitis gallstones, adopt following steps:
(1) take by weighing Rhizoma Coptidis (processed with wine) 20 gram, Radix Scutellariae (processed with wine) 20 grams, Radix et Rhizoma Rhei (stir-fried with wine) 20 grams, Flos Lonicerae 20 grams, Herba Lysimachiae 50 grams, vinegar and fry Radix Curcumae 10 grams, the Radix Aucklandiae 10 grams, stir-baked Fructus Aurantii in bran 10 grams, Radix Bupleuri (processed with vinegar) 10 grams, vinegar Rhizoma Corydalis 20 grams, Radix Clematidis 50 grams, Fructus Amomi 5 grams, vinegar Endothelium Corneum Gigeriae Galli (parched) 10 grams, Fructus Crataegi (parched to brown) 20 grams, Fructus Mume 40 grams, Spora Lygodii 20 grams, Radix Codonopsis 10 grams, Rhizoma Dioscoreae (parched with bran) 10 grams, the sweet Radix Astragali 10 grams, Pericarpium Zanthoxyli 5 grams, Rhizoma Cyperi 20 grams, subsequent use behind the decontamination;
(2) with above-mentioned raw materials medicine mixing, last pot steamed 30 minutes, dried in the shade;
(3) with 2500 milliliter 70% brewing grains white spirit bubble 14 days, get 30 milliliters of stock solutions then and be blended into 0.5 kilogram of pure water mixing, can take by 500 milliliters/bottled bottle.
Embodiment 3:
The Chinese medicine oral liquid of this treatment cholecystitis gallstones, process by the component of following weight:
Rhizoma Coptidis (processed with wine) 30 grams, Radix Scutellariae (processed with wine) 30 grams, Radix et Rhizoma Rhei (stir-fried with wine) 40 grams, Flos Lonicerae 40 grams, Herba Lysimachiae 70 grams, vinegar are fried Radix Curcumae 30 grams, the Radix Aucklandiae 20 grams, stir-baked Fructus Aurantii in bran 30 grams, Radix Bupleuri (processed with vinegar) 30 grams, vinegar Rhizoma Corydalis 40 grams, Radix Clematidis 70 grams, Fructus Amomi 15 grams, vinegar Endothelium Corneum Gigeriae Galli (parched) 25 grams, Fructus Crataegi (parched to brown) 40 grams, Fructus Mume 50 grams, Spora Lygodii 40 grams, Radix Codonopsis 30 grams, Rhizoma Dioscoreae (parched with bran) 30 grams, the sweet Radix Astragali 30 grams, Pericarpium Zanthoxyli 20 grams.
Embodiment 4: clinical observation
(1) physical data
The inventor carries out clinical observation treatment to 360 routine cholecystitis gallstones patients so far in nineteen ninety, and the age 27, the course of disease did not wait in 1 year-11 years by 71 years old.
(2) Therapeutic Method: with the embodiment of the invention 1 made oral liquid, once a day, once obey 50 milliliters, obeyed 10 days for one bottle, morning, (medicine) being taken before meal usefulness was had a meal after 1 hour again, and 30 days is a course of treatment, and can cure general 1-6 course of treatment.
Taboo: period in a medicine fasting maror, Chinese liquor and contain the Western medicine of one type of sulbactam.
(3) efficacy assessment standard
" healing ": the clinical symptoms sign disappears, and recovers normal.
" produce effects ": basic or most of disappearance of clinical symptoms sign.
" effectively ": clinical symptoms is clearly better or takes a turn for the better.
Engineering noise: the clinical symptoms sign does not have improvement.
(4) therapeutic effect:
Clinical cure 266 examples account for 74%; Produce effects 47 examples account for 13%; Effective 40 examples account for 11%; Invalid 7 examples, total effective rate 98%.
Model case:
1 Zhang, the man, 33 years old, suffer from cholecystitis, it is not good to punish therapeutic effect outside, comes the here treatment.Take the embodiment of the invention 1 made oral liquid treatment, once a day, once obey 50 milliliters, obeyed 10 days for one bottle, morning, (medicine) being taken before meal usefulness was had a meal after 1 hour again.30 days is a course of treatment, and cure three courses of treatment, through following up a case by regular visits to not recurrence.
2 are permitted certain, the woman, and 48 years old, 3 years surplus therapeutic effect elsewhere of trouble cholecystitis gallstones were not good, take the embodiment of the invention 1 made oral liquid treatment, once a day, once obey 50 milliliters, obeyed 10 days for one bottle, and morning, (medicine) being taken before meal usefulness was had a meal after 1 hour again.30 days is a course of treatment, and cure five courses of treatment.
3 Wang, the man, 60 years old, it was surplus to suffer from cholecystitis 10 years, and the angry state of an illness of drinking increases the weight of, and suffers from cholecystitis through examination in hospital, takes the embodiment of the invention 1 made oral liquid treatment, once a day, once obeys 50 milliliters, one bottle of clothes 10 days, morning, (medicine) being taken before meal usefulness was had a meal after 1 hour again.30 days is a course of treatment, and cure four courses of treatment.