CN101970454A - 修饰肽的方法 - Google Patents

修饰肽的方法 Download PDF

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Publication number
CN101970454A
CN101970454A CN2008801263346A CN200880126334A CN101970454A CN 101970454 A CN101970454 A CN 101970454A CN 2008801263346 A CN2008801263346 A CN 2008801263346A CN 200880126334 A CN200880126334 A CN 200880126334A CN 101970454 A CN101970454 A CN 101970454A
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CN
China
Prior art keywords
peptide
group
arbitrary
amino acid
trypsin degradation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2008801263346A
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English (en)
Chinese (zh)
Inventor
文哲·斯坦森
欧斯汀·瑞克德尔
约翰·希谷尔德·斯万德森
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Lytix Biopharma AS
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Lytix Biopharma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lytix Biopharma AS filed Critical Lytix Biopharma AS
Publication of CN101970454A publication Critical patent/CN101970454A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/062—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha- or omega-carboxy functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2008801263346A 2007-12-20 2008-12-22 修饰肽的方法 Pending CN101970454A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0724953.5A GB0724953D0 (en) 2007-12-20 2007-12-20 Methods of peptide modification
GB0724953.5 2007-12-20
PCT/GB2008/004244 WO2009081151A2 (fr) 2007-12-20 2008-12-22 Procédés de modification d'un peptide

Publications (1)

Publication Number Publication Date
CN101970454A true CN101970454A (zh) 2011-02-09

Family

ID=39048524

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801263346A Pending CN101970454A (zh) 2007-12-20 2008-12-22 修饰肽的方法

Country Status (8)

Country Link
US (1) US9212202B2 (fr)
EP (1) EP2235039A2 (fr)
JP (1) JP5433586B2 (fr)
CN (1) CN101970454A (fr)
AU (1) AU2008339610B2 (fr)
CA (1) CA2709881A1 (fr)
GB (1) GB0724953D0 (fr)
WO (1) WO2009081151A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0818074D0 (en) 2008-10-02 2008-11-05 Lytix Biopharma As Treatment of biofilms
GB0818072D0 (en) 2008-10-02 2008-11-05 Lytix Biopharma As Compounds
ES2712805T3 (es) * 2011-06-15 2019-05-14 Resother Pharma Aps Næsseslottet Productos farmacéuticos antiinflamatorios
GB202008980D0 (en) * 2020-06-12 2020-07-29 Amicoat As Medical devices and materials
GB202008978D0 (en) * 2020-06-12 2020-07-29 Amicoat As Antimicrobial formulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69530392D1 (de) * 1994-07-11 2003-05-22 Athena Neurosciences Inc Inhibitoren der leukozytenadhäsion
US5468843A (en) * 1994-09-08 1995-11-21 Perkin-Elmer Acetic anhydride activation for C-terminal protein sequencing
GB0005703D0 (en) 2000-03-09 2000-05-03 Alpharma As Compounds
EP1896048A4 (fr) * 2005-05-06 2010-11-03 Bayer Pharmaceuticals Corp Agonistes du recepteur (vpac2) du peptide activant l'adenylate cyclase hypophysaire (pacap) et leurs procedes pharmacologiques d'utilisation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JOHAN SVENSON ET.AL: "Albumin Binding of Short Cationic Antimicrobial Micropeptides and Its Influence on the in", 《J. MED. CHEM》 *
LAURENCE H. BRINCKERHOFF1 ET.AL: "TERMINAL MODIFICATIONS INHIBIT PROTEOLYTIC DEGRADATION OF ANIMMUNOGENIC MART-127–35 PEPTIDE: IMPLICATIONS FOR PEPTIDE VACCINES", 《INT. J. CANCER》 *
LIV TONE ELIASSEN ET.AL: "Enhanced Antitumour Activity of 15-residue Bovine Lactoferricin Derivatives Containing Bulky Aromatic Amino Acids and Lipophilic N-terminal Modifications", 《J. PEPTIDE SCI. 》 *

Also Published As

Publication number Publication date
EP2235039A2 (fr) 2010-10-06
WO2009081151A2 (fr) 2009-07-02
GB0724953D0 (en) 2008-01-30
US20110143384A1 (en) 2011-06-16
US9212202B2 (en) 2015-12-15
CA2709881A1 (fr) 2009-07-02
AU2008339610A1 (en) 2009-07-02
JP2011507821A (ja) 2011-03-10
JP5433586B2 (ja) 2014-03-05
AU2008339610B2 (en) 2014-10-02
WO2009081151A3 (fr) 2009-10-15

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SE01 Entry into force of request for substantive examination
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RJ01 Rejection of invention patent application after publication

Application publication date: 20110209