CN101953948B

CN101953948B - Medicine used for curing diabetes of deficiency of Qi-Yin syndrome

Info

Publication number: CN101953948B
Application number: CN2010102912507A
Authority: CN
Inventors: 李小杵
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-09-19
Filing date: 2010-09-19
Publication date: 2012-05-09
Anticipated expiration: 2030-09-19
Also published as: CN101953948A

Abstract

A medicine used for curing the diabetes of deficiency of Qi-Yin syndrome is prepared from the following raw material traditional Chinese medicines in parts by weight: 8-15 parts of American ginseng, 3-6 parts of pantotrichum, 3-6 parts of turtle shell, 3-6 parts of the root of rehmannia, 3-6 parts of Chinese wolfberry, 3-6 parts of the root of straight ladybell, 2-4 parts of agilawood and 15-30 parts of bitter wild vegetable and the raw materials are grinded to fine powder to prepare powder, wherein the bitter wild vegetable is the equal-quality mixture of seven edible wild vegetables, namely hill kumaitupian, Cephalanoplos segetum, alfalfa, Amaranthus viridis L., sow thistle, Chenopodium iljinii and parslane herb. The medicine of the invention has the functions of nourishing qi and yin, nourishing yin and yang, promoting qi and reducing blood sugar and is suitable for the curing of the the diabetes of deficiency of Qi-Yin syndrome. Fifty patients with the diabetes of deficiency of Qi-Yin syndrome have taken the medicine of the invention by mouth for 3 treatment periods; and 15 cases were significantly effective, 24 cases were effective and 11 cases were failed, thus the total effective rate is 78%.

Description

A kind of medicine of treating Qi and Yin deficiency diabetes mellitus

Technical field

The present invention relates to a kind of medicine of treating diabetes, particularly relating to a kind of is the medicine of the treatment Qi and Yin deficiency diabetes mellitus of feedstock production with the Chinese crude drug.

Background technology

Diabetes spp is in the traditional Chinese medical science category of " quenching one's thirst ", be a kind of be the incretion disease of main performance with the carbohydrate metabolism disturbance.Its sickness rate is high, and the course of disease is long, and radical cure is difficult, and the fatality rate that disables is only second to tumor and cardiovascular disease, so classified as one of the world's three serious diseases.

The western medical treatment diabetes are used sulphanylureas, biguanides or trypsin class medicine mostly, though its hypoglycemic activity is obvious, only can reach the degree of regulating metabolism disorder, and side effect are big, takes grievous injury liver, kidney for a long time, influences gastrointestinal function.Medicine is difficult to control especially for the complication of diabetes.

TCM treatment of diabetes is with a long history; Ancient Chinese medicine doctor is thought: not enough because of the plain body deficiency of YIN or natural endowment in the morbidity of diabetes; Outer because eating and drinking without temperance, surfeit delicious food pure wine, or direct stimulation, disorder of emotion, or inducement such as labor is desired excessively, the cloudy essence of loss and causing a disease.Damage of kidney-YIN is this, and lung dryness of the stomach heat is mark.Treatment is the main side's of something lost medication with enriching yin and nourishing kidney, such as LIUWEI DIHUANG WAN, diabetes pill or the like.Though this type of prescription has certain therapeutical effect to diabetes, prove that according to traditional Chinese medical science negative and positive academic viewpoint and clinical practice sick deficiency of YIN affecting YANG for a long time causes deficiency of both YIN and YANG or change positive person by the moon of common occurrence.Therefore, enriching yin and nourishing kidney are only paid attention in treatment by Chinese herbs in the past, think little of the adjustment of human body yin-yang balancing, can not give treatment pointedly according to the clinical manifestation that diabetics varies, and curative effect is not ideal enough as a result.

Summary of the invention

The purpose of this invention is to provide a kind of Chinese medicine medicine of treating Qi and Yin deficiency diabetes mellitus, this medicine is characteristics to improve patient's immunity with the adjustment human body yin-yang balancing, treatment Qi and Yin deficiency diabetes mellitus good effect, instant effect.

Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Radix Panacis Quinquefolii 8～15 Cornu Cervi Pantotrichums 3～6 Carapax Trionycis 3～6

The Radix Rehmanniae 3～6 Fructus Lycii 3～6 Radix Adenophorae (Radix Glehniae) 3～6

Lignum Aquilariae Resinatum 2～4 bitter wild herbs 15～30.

Wherein, described bitter wild herbs be open-minded dish, field thistle, Herba Medicaginis, Herba amaranthi ascendentis, Herba Sonchi Oleracei, Chenopodium album, seven kinds of edible wild herbs of Herba Portulacae etc. the quality mixture.

The preferred weight umber of said each crude drug is:

Radix Panacis Quinquefolii 10 Cornu Cervi Pantotrichums 5 Carapax Trionycis 5

The Radix Rehmanniae 5 Fructus Lycii 5 Radix Adenophorae (Radix Glehniae) 5

Lignum Aquilariae Resinatum 3 bitter wild herbs 20.

The medicine of above-mentioned each component can be processed said peroral dosage form on any pharmaceuticss such as tablet, pill, powder, capsule, and the preferred dosage form of the present invention is a powder.

Above-mentioned each crude drug is removed impurity, clean, mix, be ground into fine powder, process the powder of brown after the sterilization, pack, every bag 10 gram according to said parts by weight.

Motherland's medical science thinks that vigour is weak, deficiency of spleen-QI; Unit's deficiency of YIN is few, and it is the main cause that primary diabetes mellitus forms that deficiency of spleen-YIN and irritability are not dredged, and the sweet fertilizer of diet also is this disease morbidity assignable cause.In the medicament composing prescription of the present invention, Radix Panacis Quinquefolii property is put down little cold, is gone into spleen, lung meridian, strongly invigorating primordial QI, and the cough-relieving of promoting the production of body fluid, blood sugar lowering is fundamentally treated diabetes; The Cornu Cervi Pantotrichum sweet in the mouth becomes, and is warm in nature, goes into liver, kidney channel, and spermatogenesis is mended marrow, the Yiyang of nourishing blood, and strengthening the tendons and bones cooperates Radix Ginseng, Carapax Trionycis complement sun, invigorating primordial QI and complement cloudy, and ternary makes negative and positive be able to balance with mending; Carapax Trionycis distinguishes the flavor of, sweet, cold nature is gone into liver, kidney channel, for primordial qi strengthening is cloudy, spleen is cloudy will article, Kidney-Yin, the cloudy foot of spleen are then quenched one's thirst and are removed; Radix Rehmanniae sweet in the mouth, cold in nature, enriching yin and nourishing kidney, clearing away heat and cooling blood, hemostasis, compatibility Carapax Trionycis complement is cloudy, compatibility Radix Panacis Quinquefolii blood sugar lowering; The Fructus Lycii sweet in the mouth, property is flat, goes into liver, kidney channel, is the good merchantable brand of nourishing kidney yin, and hypoglycemic activity is strong, cures mainly to quench one's thirst, and joins the Radix Rehmanniae, Radix Panacis Quinquefolii makes its blood sugar reducing function multiplication; Radix Adenophorae (Radix Glehniae) sweet in the mouth, cold nature is gone into lung, stomach warp, nourishing the lung to arrest cough, nourishing the stomach ends Tianjin, joins Carapax Trionycis, Radix Rehmanniae yin nourishing, and what stomach-fire victor, rapid digestion of food and polyorexia person used then imitates; The Lignum Aquilariae Resinatum acrid in the mouth is bitter, and is warm in nature, goes into spleen, stomach, kidney channel, and fortune vigour is used for part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels unit YANG deficiency, can rise and can fall, and can complementary energy rush down, and can open can be solid, the vigour of can passing through; Bitter wild herbs include seven kinds of open-minded dishes, field thistle, Herba Medicaginis, Herba amaranthi ascendentis, Herba Sonchi Oleracei, Chenopodium album, Herba Portulacae, and flavor is all bitter, sweet, cold; Go into lung, stomach, large intestine channel, contain abundant calabash Bu Su, riboflavin, vitamin C and trace element such as calcium, ferrum, nutritious; Can mend and to rush down; The pathogenic fire purging heat clearing away removes damp and hotly, and blood fat reducing, hypoglycemic activity are obvious.More than all medicine compatibilities, gas cloudy two helps, and can reach following effect:

1, gas cloudy two is mended

The Radix Panacis Quinquefolii invigorating primordial QI, Radix Rehmanniae tonifying kidney-yin.

2, strengthening both YIN and YANG

Cornu Cervi Pantotrichum complement sun, the Carapax Trionycis complement is cloudy.

3, circulation of qi promoting

Circulation of qi promoting is the key of treatment Qi and Yin deficiency diabetes mellitus, and vigour, Kidney-Yin, Yuanyang need be failed cloth, and the shape that irritability is not dredged must be regulated the flow of vital energy with harmonizing the functional activities of vital QI, and the Lignum Aquilariae Resinatum circulation of qi promoting of regulating the flow of vital energy is so that full side's tonify without causing stagnation.

4, blood sugar lowering

Carapax Trionycis, the Radix Rehmanniae, Radix Adenophorae (Radix Glehniae), Fructus Lycii, Radix Panacis Quinquefolii all have the effect of blood sugar lowering, and bitter wild herbs bitter in the mouth has the effect of dissolving sugar in digestion process.

Medicine of the present invention is applicable to the treatment of Qi and Yin deficiency diabetes mellitus, has treating both the principal and secondary aspects of a disease, gas cloudy two and helps, can attack and can mend and the effect of regulating YIN and YANG, takes for a long time to have no side effect.

For further investigating the clinical efficacy of Drug therapy Qi and Yin deficiency diabetes mellitus of the present invention, select 50 routine Qi and Yin deficiency diabetes mellitus patients to carry out clinical observation on the therapeutic effect.

Select outpatient's 50 examples, wherein male 27 examples, women 23 examples, at 35～64 years old age, the course of disease is the shortest 6 months, and is the longest 4 years.

Diagnostic criteria: with reference to the diabetes clinical diagnosis standard of World Health Organization's formulation in 1999.Get rid of 1) secondary diabetes that causes of other reasons, like acromegaly, hypercortisolism, have a liking for and cough up glucagonoma etc.; 2) merge serious primary disease such as cardiovascular, liver, kidney and hemopoietic system and psychotic; 3) gestation or age of sucking the patient, to this medicine allergy sufferers; 4) blood insulin is normal or be lower than normal person; 5) all do not meet include in standard person, not by stipulate the pill taker, can't formulate curative effect person and data not Quan Zhe etc. affect the treatment or safety judgement person.

The differential diagnosis in tcm red tongue, few tongue, dry tongue or not dried, thin, few gloss, few refreshing, xerostomia is polydipsia not, constipation, just dried back is half congealed, and obstinate disease is Qi and Yin deficiency diabetes mellitus.

Therapeutic Method

Oral medicine of the present invention, every day 3 times, each 10 grams, mixing in water for oral taking.2 months is a course of treatment, takes 3 courses of treatment continuously.Irritable foods such as the period in a medicine fasting is raw and cold, greasy, pungent.

Criterion of therapeutical effect

Observation index is measured blood, glucose in urine and the insulin before and after the treatment.Criterion of therapeutical effect is according to " new Chinese medicine clinical research guideline " point system.Asymptomatic is 0 minute, slightly be reduced to 2 fens, moderate or medium be 4 minutes, severe or heavily be 6 minutes.Produce effects: treatment back clinical symptom disappearance, or fasting glucose is less than 6.1mmol/L; Effectively: treatment back clinical symptoms scoring value descends 1/3～2/3, and fasting glucose is than the 2.0～3.0mmol/L that descends before treating; Invalid: treatment back clinical symptoms scoring value descends less than 1/3, and fasting glucose descends not obvious.

Therapeutic outcome

3 courses of treatment of 50 routine patient's oral administration Drug therapy of the present invention, produce effects 15 examples, effective 24 examples, invalid 11 examples, total effective rate 78%.

The specific embodiment

Embodiment 1

Get and obtain bitter wild herbs after removing impurity, the open-minded dish that cleans up, field thistle, Herba Medicaginis, Herba amaranthi ascendentis, Herba Sonchi Oleracei, Chenopodium album, each 5kg mix homogeneously of seven kinds of edible wild herbs of Herba Portulacae.

With taking by weighing the bitter wild herbs mix homogeneously of the Radix Panacis Quinquefolii 4kg, Cornu Cervi Pantotrichum 1kg, Carapax Trionycis 1.8kg, Radix Rehmanniae 1.2kg, Fructus Lycii 1.2kg, Radix Adenophorae (Radix Glehniae) 1.2kg, Lignum Aquilariae Resinatum 1kg and the 8kg that remove impurity, clean up; Be ground into 100 purpose fine powders; Pack, every bag 10 restrains, and processes the powder of brown behind the sterilization.

Embodiment 2

With taking by weighing the bitter wild herbs mix homogeneously of the Radix Panacis Quinquefolii 2.5kg, Cornu Cervi Pantotrichum 1.8kg, Carapax Trionycis 0.9kg, Radix Rehmanniae 1.8kg, Fructus Lycii 1.8kg, Radix Adenophorae (Radix Glehniae) 1.8kg, Lignum Aquilariae Resinatum 0.9kg and the 9kg that remove impurity, clean up; Be ground into 100 purpose fine powders; Pack; Restrain for every bag 10, process the powder of brown behind the sterilization.

Embodiment 3

With taking by weighing the bitter wild herbs mix homogeneously of the Radix Panacis Quinquefolii 3kg, Cornu Cervi Pantotrichum 1.5kg, Carapax Trionycis 1.5kg, Radix Rehmanniae 1.5kg, Fructus Lycii 1.5kg, Radix Adenophorae (Radix Glehniae) 1.5kg, Lignum Aquilariae Resinatum 0.6kg and the 6kg that remove impurity, clean up; Be ground into 100 purpose fine powders; Pack; Restrain for every bag 10, process the powder of brown behind the sterilization.

Claims

1. medicine of treating Qi and Yin deficiency diabetes mellitus is to be that crude drug prepares by following parts by weight of traditional Chinese medicines:

Lignum Aquilariae Resinatum 2～4 bitter wild herbs 15～30

2. the medicine of treatment Qi and Yin deficiency diabetes mellitus according to claim 1 is characterized in that the parts by weight of said each crude drug are:

Radix Panacis Quinquefolii 10 Cornu Cervi Pantotrichums 5 Carapax Trionycis 5

The Radix Rehmanniae 5 Fructus Lycii 5 Radix Adenophorae (Radix Glehniae) 5

Lignum Aquilariae Resinatum 3 bitter wild herbs 20.