CN101946865A - Premix for preventing and curing broiler leg diseases - Google Patents

Premix for preventing and curing broiler leg diseases Download PDF

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Publication number
CN101946865A
CN101946865A CN2010102792810A CN201010279281A CN101946865A CN 101946865 A CN101946865 A CN 101946865A CN 2010102792810 A CN2010102792810 A CN 2010102792810A CN 201010279281 A CN201010279281 A CN 201010279281A CN 101946865 A CN101946865 A CN 101946865A
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vitamin
fryer
preventing
compound premix
premix
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CN101946865B (en
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刘雪兰
石天虹
张桂芝
黄宝华
井庆川
武彬
魏祥法
刘瑞亭
阎佩佩
刘涛
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Poultry Research Institute Shandong Academy of Agricultural Sciences
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Abstract

The invention discloses a compound premix for preventing and curing broiler leg diseases, belonging to the field of animal nutrition, which is prepared by mixing important vitamins related to bone metabolism, trace elements, mineral substances, probiotics capable of preventing and curing the broiler bacterial leg diseases and some functional substances based on a certain ratio. The premix not only considers the requirements on bone growth and development of broilers on vitamins, trace elements and mineral substances, but also takes the interaction of the above substances and the relationship between the above substances and phosphorus and calcium into account. Contrast tests prove that the special feed for broilers can prevent and cure broiler leg diseases, lower the mortality of broilers, promote growth and reduce the feed-gain ratio, thereby improving the cultivation benefit.

Description

A kind of premix that prevents and treats fryer leg disease
Technical field
The technology of the present invention belongs to the animal nutrition field, relates to a kind of feed, relates in particular to a kind of premix that prevents and treats fryer leg disease.
Background technology
Fryer leg disease is the common frdquently encountered disease of fryer, shows as skelasthenia, and textured bone and joint tumour etc. cause limping, paralysis.At present, the sick incidence of disease of China's fryer leg is about 3%~12%, and severe patient is one of insoluble three big Nutrition and Metabolism diseases up to more than 30%.Fryer leg disease causes higher death rate on the one hand, and owing to " weak leg ", fryer can not be stood, and brings out the chest tumour, has reduced the quality and the grade of chicken on the other hand, cultures to fryer and causes bigger economic loss.
The leg disease is divided into the sick and neuromuscular leg disease of bone leg.Bone leg disease is owing to calorie-protein concentration height in the feed, the vitamin relevant with skeleton development, mineral element lack or proportional imbalance, causing grows between musculature and the skeletal tissue imbalance occurs, thereby growing of skeletal system had problems.Vitamin A, vitamin D, biotin, choline, pantothenic acid and nicotinic acid are several important vitamin relevant with skeletal metabolism.Vitamin A is relevant with the growth of cartilage, VAD, and incoordination can appear in fryer; Vitamin A is too much, causes bone strength to reduce, and similar rachitic symptom appears in bone deliquescing, easy to break, shin bone epiphysis increase, the minimizing of bone mineral matter etc.Vitamin D can promote the absorption of skeletal calcium phosphorus, and vitamin D deficiency causes tangible textured bone, and the epiphysis calcification of shin bone and femur is bad; Vitamin D is excessive, and the calcium salt resorption becomes fragile bone in the bone, causes deformity and fracture.Biotin, choline, pantothenic acid and nicotinic acid deficiency all show the short and thick disease of bone.Calcium, phosphorus, manganese, zinc, copper are the important mineral elements relevant with bone growth and development.Fryer is more to calcium, phosphorus requirement, though when lacking calcium, phosphorus or having enough calcium, phosphorus to supply with, both ratios are improper, and fryer all can not absorb calcium, phosphorus well, thereby causes the generation of leg disease.Copper, zinc, manganese deficiency bring out shin bone tubbiness disease.Neuromuscular leg disease is owing to lack some nutrient in the daily ration, makes fryer nerve fiber and musculature generation pathology and shows as the shank spasm, can not stand.During TD, because sick chicken cerebromalacia causes incoordination, two leg generation spasmodic tics.Cobastab 1(thiamine) shortage causes the peripheral nerve paralysis, and sick chicken is " sight star " posture or penguin posture.Cobastab 2The symptom that (riboflavin) lacks is that the toe pawl of disease chicken inwardly curls, two acroparalysis, and the leg muscle atrophy is also loose.When lacking selenium, leg amyotrophia causes disease chicken astasia, two acroparalysis.
The Animal nutrition worker had once carried out the research of mechanism aspect to the interaction between the nutrient that influences the skeletal calcium phosphorus metabolism both at home and abroad.Result of study is: (1) vitamin A has identical absorption approach with vitamin D at enteron aisle, the phase mutual interference, and influence absorbs; At liver, vitamin A influences the generation of vitamin D activated product; At osteocyte, the ratio of vitamin A and vitamin D plays crucial effect to position and the quantity that is maintained in osteocyte and osteoclast.(2) high-caliber calcium, phosphorus form cotton-shaped colloidal precipitation in the alkaline environment of enteron aisle, and trace elements such as absorption manganese, zinc make it to excrete with ight soil, thereby influence the absorption of manganese, zinc; Calcium, the too high utilization that can hinder trace elements such as copper, zinc of phytic acid content in the daily ration.(3) metabolite 1 of vitamin D, 25-(OH) 2D 3Or 25-(OH) D 3Suitable concentration and the calcium trophic level between have very strong mutual work, calcium level is low more in the daily ration, then the metabolite dosage of required vitamin D is big more, and the dosage of metabolite is crossed conference and caused hypercalcemia and suppress growth.
Summary of the invention
More than in the research, the suggestion amount has very big-difference in the level of each nutrient that experimental design is set and each trophic level, cause achievement in research to be difficult to be applied to production practices, for this reason, on the basis of forefathers' research, the present invention is a foundation with NRC (1994 editions) feeding of broiler standard and China's fryer industry standard, sick with prevention fryer leg is purpose with instructing production practices, to the vitamin D sick relevant with leg, vitamin A, vitamin E, calcium, phosphorus, manganese, copper, the suitable addition and the ratio of zinc have been carried out great deal of experimental work, drawn the best proportioning between each nutrient, concrete outcome is: vitamin A: vitamin D=4~5: 1, vitamin A: vitamin E=0.8~0.9: 1, calcium: phosphorus=2~2.6: 1, manganese: zinc: copper=16: 8: 1.
On the basis of above-mentioned experimental study, the present invention is actual further combined with producing, will with bone, nerve, vitamin and mineral element and some functional materials that muscle metabolism is relevant, prepare according to certain ratio, developed a kind of fryer of promotion bone growth and development that has, economize on resources, alleviate the premix of the control fryer leg disease of advantages such as environmental pollution.
The technical solution adopted in the present invention is: a kind of compound premix of preventing and treating fryer leg disease, it is characterized in that the component of described compound premix and weight portion are: B B-complex 0.2-0.6, composite trace element 2-4, Choline Chloride 1-2, methionine 3-4, lysine 2-4, threonine 2-5, calcium monohydrogen phosphate 18-22, stone flour 20-30, salt 5-6, probiotic (useful total viable count 〉=2 * 10 8CFU/g) 2-4, phytase (live: 5000U/g) 0.1-0.4, dregs of beans 18-44.7 by enzyme.
Every kilogram contains following composition in the described B B-complex: vitamin A 40000000IU, vitamin D 310000000IU, vitamin E 50000000IU, vitamin K 34500mg, Cobastab 15000mg, Cobastab 215000mg, calcium pantothenate 40000mg, nicotinic acid 85000mg, Cobastab 1215000mg, biotin (biotin) 5000mg, folic acid 1800mg, antioxidant (weight percentage of active ingredient ethoxyquinoline is 10%) 500mg.
Described composite trace element contains following composition for every kilogram: copper sulphate 17g, zinc sulfate 99g, manganese sulfate 217g, ferrous sulfate 73g, sodium selenite 3g.
The technical solution adopted for the present invention to solve the technical problems can also be further perfect, and this premix is by weight made by following constituent optimization combination: B B-complex 0.3-0.5, composite trace element 2.5-3.5, Choline Chloride 1-2, methionine 3-4, lysine 2.5-3.5, threonine 3-4, calcium monohydrogen phosphate 19-21, stone flour 20-30, salt 5-6, probiotic 2-3.5, phytase 0.1-0.4, dregs of beans 21.6-41.6.
This premix is by weight formed by following component is optimum: B B-complex 0.4, composite trace element 3, Choline Chloride 1.0, methionine 3, lysine 2, threonine 2, calcium monohydrogen phosphate 18, stone flour 20, salt 6, probiotic 2, phytase 0.1, dregs of beans 42.5.
The effect of each composition among the present invention:
Vitamin A: promote the growth of cartilage.
Vitamin D 3: promote the absorption of skeletal calcium phosphorus.
Vitamin E: biocatalyst, antioxidant, prevention chick cerebromalacia and two leg generation spasmodic tics.
Cobastab 1: participate in carbohydrate, amino acid whose metabolism, strengthen the synthetic of body fat, promote the digestive function of animal, during shortage, chicken peripheral nerve paralysis.
Cobastab 2: promote metabolism as coenzyme.
Calcium pantothenate: participate in the metabolism of carbohydrate, fat and protein.
Choline Chloride: promote chick growth, prevention shin bone tubbiness.
Copper sulphate: copper is provided, and copper is the constituent of many enzymes in the body, has multiple function, as the formation of bone, erythrocytic generation etc.
Zinc sulfate: mainly participate in carbohydrate, lipid and protein metabolism.
Manganese sulfate: the composition that mainly participates in some enzymes of carbohydrate, lipid and protein metabolism.
Sodium selenite: be the constituent of glutathione peroxidase, play the protection cell membrane, and can prevent the generation of some disease, also have anti-stress effect.
Calcium monohydrogen phosphate: required phosphorus of bone growth and calcium are provided.
Stone flour: provide bone growth required calcium.
Probiotic: adjust the gut flora balance, suppress harmful bacteria, the leg disease that the prevention harmful bacteria causes promotes growth.
Phytase: phytic acid (salt) is degraded to inositol and Phos, improves the utilization rate of phytate phosphorus, discharge other nutriment that combines with phytic acid (salt) simultaneously.
Methionine: participate in transfer and the metabolism of phosphorus and the synthesizing of adrenaline, choline and creatine of methyl in the body; Being the raw material of synthetic protein and cystine, is methyl donor.
Lysine: can promote to grow, strengthen immunologic function.
Threonine: the important component part of constituting body albumen, participate in the synthetic of protein, regulate feed intake, influence the body fat metabolism, improve immunity function and growth performance.
Salt: keep the cylinder electrolyte balance, improve appetite, promote digestion.
Dregs of beans: diluent.
The present invention had both considered that the fryer bone growth and development was to vitamin A, vitamin D 3, E, copper, manganese, zinc, etc. requirement, considered again between them interaction and and calcium phosphorus between relation, develop specific complex vitamin and composite trace element.On the basis of adding specific complex multidimensional and composite trace element, Choline Chloride, calcium monohydrogen phosphate, stone flour, salt, probiotic, phytase etc. have been added especially, by meticulous collocation to above various raw materials, this fryer premix compound special material can be prevented and treated the generation of fryer leg disease, can promote the growth of fryer again, thereby improve the fryer culture benefit.
The specific embodiment
Embodiment 1
Proportioning (percetage by weight): B B-complex 0.4%, composite trace element 3%, Choline Chloride 1.0%, methionine 3%, lysine 2%, threonine 2%, calcium monohydrogen phosphate 18%, stone flour 20%, salt 6%, probiotic 2%, phytase 0.1%, dregs of beans 42.5%.
Embodiment 2
Proportioning (percetage by weight): B B-complex 0.5%, composite trace element 3.6%, Choline Chloride 1.2%, methionine 3%, lysine 2%, threonine 2%, calcium monohydrogen phosphate 21.6%, stone flour 24%, salt 6%, probiotic 2%, phytase 0.3%, dregs of beans 33.8%.
Embodiment 3
Proportioning (percetage by weight): B B-complex 0.35%, composite trace element 2.75%, Choline Chloride 1%, methionine 3%, lysine 2%, threonine 2%, calcium monohydrogen phosphate 18%, stone flour 20%, salt 6%, probiotic 2%, phytase 0.4%, dregs of beans 42.5%.
Experimental example: respectively in Jinan City's bridge town, Liaocheng City Yanggu County, Liangshan County fryer culture experiment base, Jining City carry out the feeding comparative trial, contrast with " very lucky feed ", " many cities feed ", " the beneficial good feed " of premix of the present invention (prescription of embodiment 1) and buying from the market.4 identical hen houses of condition are selected in each proving ground, every 1000 1 aa broiler chicken, be divided into 5 repeating groups, 200 of every repetitions, half and half, the 1 hen house of male and female adopts premix of the present invention, and the 2nd hen house adopts " very lucky feed ", the 3rd hen house to adopt " many cities feed ", the 4th hen house to adopt " beneficial good feed ", feeding and management method is identical, 8 weeks of experimental period.
Contrast experiment's effect of 3 kinds of different premixes of market purchasing of adding the premix of the present invention (prescription of embodiment 1) of 5% (wt/wt) and 5% (wt/wt) in the test fryer complete diet pellet prescription (seeing Table 1) respectively is shown in table 2~4:
Table 1 fryer complete diet pellet prescription
Figure BSA00000266141000061
Annotate: above-mentioned percentage all is percetage by weight
Bridge town, table 2 Jinan City result of the test
Table 3 Liaocheng City Yanggu County result of the test
Figure BSA00000266141000071
Table 4 Jining City Liangshan County result of the test
Figure BSA00000266141000072
From table 2~4 as can be seen, premix of the present invention can prevent and treat generation, reduction death rate, reduction feedstuff-meat ratio, the promotion growth of fryer leg disease significantly.

Claims (5)

1. a compound premix of preventing and treating fryer leg disease is characterized in that, the component of described compound premix and weight portion are: B B-complex 0.2-0.6, composite trace element 2-4, Choline Chloride 1-2, methionine 3-4, lysine 2-4, threonine 2-5, calcium monohydrogen phosphate 18-22, stone flour 20-30, salt 5-6, probiotic 2-4, phytase 0.1-0.4, dregs of beans 18-44.7; Useful total viable count 〉=2 * the 108CFU/g of described probiotic; Described phytase activity is 5000U/g.
2. a kind of compound premix of preventing and treating fryer leg disease as claimed in claim 1 is characterized in that described B B-complex contains following composition for every kilogram: vitamin A 40000000IU, vitamin D 310000000IU, vitamin E 50000000IU, vitamin K 34500mg, Cobastab 15000mg, Cobastab 215000mg, calcium pantothenate 40000mg, nicotinic acid 85000mg, Cobastab 1215000mg, biotin 5000mg, folic acid 1800mg, antioxidant 500mg; The weight percentage of active ingredient ethoxyquinoline is 10% in the described antioxidant.
3. a kind of compound premix of preventing and treating fryer leg disease as claimed in claim 2 is characterized in that, described composite trace element contains following composition for every kilogram: copper sulphate 17g, zinc sulfate 99g, manganese sulfate 217g, ferrous sulfate 73g, sodium selenite 3g.
4. as any described a kind of compound premix of preventing and treating fryer leg disease among the claim 1-3, it is characterized in that the component of described compound premix and weight portion are: B B-complex 0.3-0.5, composite trace element 2.5-3.5, Choline Chloride 1-2, methionine 3-4, lysine 2.5-3.5, threonine 3-4, calcium monohydrogen phosphate 19-21, stone flour 20-30, salt 5-6, probiotic 2-3.5, phytase 0.1-0.4, dregs of beans 21.6-41.6.
5. as any described a kind of compound premix of preventing and treating fryer leg disease among the claim 1-3, it is characterized in that the component of described compound premix and weight portion are: B B-complex 0.4, composite trace element 3, Choline Chloride 1.0, methionine 3, lysine 2, threonine 2, calcium monohydrogen phosphate 18, stone flour 20, salt 6, probiotic 2, phytase 0.1, dregs of beans 42.5.
CN2010102792810A 2010-09-13 2010-09-13 Premix for preventing and curing broiler leg diseases Expired - Fee Related CN101946865B (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102326691A (en) * 2011-07-14 2012-01-25 山东六和集团有限公司 Powdery material of compound feed for broilers and preparation method of powdery material
CN103082138A (en) * 2013-01-18 2013-05-08 山东省农业科学院家禽研究所 Compound premix for promoting development of body sizes and ovaries of laying hens
CN103416627A (en) * 2013-08-19 2013-12-04 临汾市通达饲料有限公司 Broiler feed
CN104304688A (en) * 2014-04-02 2015-01-28 仙桃市仙发饲料有限公司 Premixed feed for poultry, and preparation method thereof
CN106472852A (en) * 2016-09-22 2017-03-08 河北大午农牧集团种禽有限公司 One breeding hen feed premix material and chicken feed
CN107647175A (en) * 2017-11-06 2018-02-02 四川铁骑力士实业有限公司 A kind of duck mixed feed for preventing meat duck leg disease and its preparation method and application
CN107811140A (en) * 2017-11-06 2018-03-20 四川铁骑力士实业有限公司 It is a kind of to prevent kind of the duck premix of duck finishing period leg disease and its preparation method and an application

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CN101002595A (en) * 2006-01-18 2007-07-25 内蒙古草原兴发股份有限公司 Feed for young Caoyuan luniao chicken

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102326691A (en) * 2011-07-14 2012-01-25 山东六和集团有限公司 Powdery material of compound feed for broilers and preparation method of powdery material
CN103082138A (en) * 2013-01-18 2013-05-08 山东省农业科学院家禽研究所 Compound premix for promoting development of body sizes and ovaries of laying hens
CN103416627A (en) * 2013-08-19 2013-12-04 临汾市通达饲料有限公司 Broiler feed
CN104304688A (en) * 2014-04-02 2015-01-28 仙桃市仙发饲料有限公司 Premixed feed for poultry, and preparation method thereof
CN106472852A (en) * 2016-09-22 2017-03-08 河北大午农牧集团种禽有限公司 One breeding hen feed premix material and chicken feed
CN107647175A (en) * 2017-11-06 2018-02-02 四川铁骑力士实业有限公司 A kind of duck mixed feed for preventing meat duck leg disease and its preparation method and application
CN107811140A (en) * 2017-11-06 2018-03-20 四川铁骑力士实业有限公司 It is a kind of to prevent kind of the duck premix of duck finishing period leg disease and its preparation method and an application
CN107811140B (en) * 2017-11-06 2021-02-26 四川铁骑力士实业有限公司 Premix for ducks for preventing leg diseases of breeding ducks in growing period and preparation method and application thereof
CN107647175B (en) * 2017-11-06 2021-07-06 四川铁骑力士实业有限公司 Duck compound feed for preventing leg diseases of meat ducks as well as preparation method and application of duck compound feed

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