CN101927052A - Drug-detoxifying apparatus based on brain wave biofeedback - Google Patents
Drug-detoxifying apparatus based on brain wave biofeedback Download PDFInfo
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- CN101927052A CN101927052A CN200910062865XA CN200910062865A CN101927052A CN 101927052 A CN101927052 A CN 101927052A CN 200910062865X A CN200910062865X A CN 200910062865XA CN 200910062865 A CN200910062865 A CN 200910062865A CN 101927052 A CN101927052 A CN 101927052A
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Abstract
The invention discloses a drug-detoxifying apparatus based on brain wave biofeedback. The drug-detoxifying apparatus comprises the following modules: a serial port receiving module 1, a singlechip processing module 2, a DDS healing wave transmitter module 3, a treatment clock module 4, an LCD display module 5, a keyboard input module 6, an automatic acupoint searching module 7 and an auricular point sticking piece 8. The apparatus combines a traditional acupuncture principle and an advanced digital signal processing technology to generate dilatational wave in a specific frequency range to stimulate corresponding auricular points of a patient, so that plasma cortisol and plasma enkaphalin substance in the patient are adjusted to be restored to in a normal level, and simultaneously, auricular point sticking cowherb seed and the other medicine adjuvant therapy modes are used to achieve the purpose of giving up tobacco and relieving abstinence syndrome. The apparatus is provided with a precise automatic acupoint searching device and a treatment clock, thereby decreasing the problems that low treatment effect, increased relapse rate and the like are caused by incorrect automatic acupoint search and regular treatment at variable interval.
Description
Technical field
The present invention relates to a kind of treatment device, particularly a kind of drug-detoxifying apparatus based on brain wave biofeedback.This treatment device is patient's normal brain activity electric wave of gathering by micro computer, and use hyundai electronics frequency synthesis technique (DDS) to produce the treatment ripple consistent with patient's brain wave height, induce brain wave to return to normal level rapidly, reach and suppress drug addiction outbreak, the effect of rehabilitating addicts in the short time.Relate to the health care technology field.
Background technology
At present, the drug issue that is on the rise has become global disaster.The physical and mental health of spreading unchecked the direct harm people of drugs, and bring huge threat to economic growth and social progress.Statistics according to the United Nations shows, the annual drug trade volume in the whole world reaches more than 5,000 hundred million dollars, the scope that drugs spread has expanded to more than 200 countries and regions of five continents, and the number that various drugs are sucked in the whole world is up to more than 200,000,000, and wherein the person between twenty and fifty of 17～35 one full year of life account for 78%.
Drug rehabilitation method commonly used has following several:
1) natural withdrawal method: the medicine of special drug rehabilitation promptly is not provided to junkie, and rigid stopping to be taken drugs, and allows the withdrawal symptom organic growth, spontaneous regression.The application of natural withdrawal method is of long duration, but uses natural withdrawal method many decades all over the world, does not see the effect of no longer reverting to take drugs to occur learning the lesson.It is frightened that junkie is produced anti-drug institution, avoids as far as possible, loses the enthusiasm of seeking medical advice.Disconnected malicious withdrawal finishes and is not that everything is just fine, and the protracted withdrawal symptom is wanted half a year, even just desalinates after 1 year, and drug abstainer feels to endure to the fullest extent torment at any time, and the sense of craving for of drugs is caused reverting to take drugs sooner or later.
2) opioid drug substitutes decreasing therapy: this method is the longest service time in China, and the withdrawal that opiates is relied on obviously is effectively, and is clinical safe in utilization, and few side effects is applicable to opium or light heroin addiction person.But opioid drug substitutes the dosage of decreasing therapy and grasps and will appropriately measure the withdrawal of successively decreasing that is difficult for bigger than normal, measures the too small purpose that alleviates withdrawal symptom that do not reach, and must follow varying with each individual, and the principle of individuation of dosage is not easy to grasp, and is easy to cause medicine habit-forming.Drug dependence, especially opioid addiction is one of narcotic abuse problem in the our times scope, also is great society public hazards.
3) Chinese medicine detoxicity method: based on Chinese drugs dispensing, improve drug abstainer immunity, the health invigorating quality is assisted detoxification treatment.The method sphere of action is wide, and Chinese medicine compound produces effectiveness simultaneously to multiple spot in the human body, but onset is slow, and a little less than the efficacy of a drug, not long to the drug abuse time, the drug abuse amount is little, and the not serious person of physical dependence can use; But, just can not satisfy its requirement for the acute drug addiction treatment patient of needs.
4) acupuncture method of abstention: acupuncture is in the existing history in several thousand of China, on specific acupuncture point, apply stimulation could generate and secrete the similar morphine of multiple effect in brain chemical substance, break through the inhibition that exogenous Opium material causes, recover to discharge the function of endogenous Opium peptide gradually.The method must be operated by the doctor of specialty, must have accurate cognition to the acupuncture point, and onset is slow, and treatment cycle is longer.
More than several modes, all need the long cycle, the doctor of specialty carries out partner treatment, therapeutic effect has much relations with doctor's experience, and can not carry out in real time according to individual practical situation, effective feedback treats.This treatment device then can be convenient for carrying, and treats according to the personal considerations, in each therapeutic process, also can regulate according to the reaction of human body, brings into play therapeutic effect to greatest extent, shortens treatment cycle.
Summary of the invention
Existing therapeutic modality is single, to all patients' uses treatment ripple much at one, only changes the treatment intensity of wave at the each patient.The present invention is then at each routine patient, produces the most suitable himself optimal treatment ripple, thus can more targeted help its rehabilitate addicts rapidly.
This treatment device is made up of single chip control module, signal acquisition module, high-speed SRAM module, DDS treatment ripple generation module, keyboard input module, LCD display module, serial port module.
When the patient was in normal condition (drug addiction remains dormant), single chip control module obtained the normal brain activity electric wave by signal acquisition module, and was stored to EEPROM.The ordinary wave that will collect before during morbidity writes the high-speed SRAM module, obtain ill ripple by signal acquisition module simultaneously, after comparing analysis for DDS treatment ripple generation module together, produce the treatment ripple similar to the brain wave height, act on brain, directly suppress psychology and psychological need that the drug addiction outbreak produces.In therapeutic process, continuous acquisition morbid state ripple, real-time update treatment ripple acts on clearly defined objective, with strong points.
The brain wave that serial port module is used for collecting is sent to computer and sets up the data base and analyze, and also can use the computer expert to cross the serial port module file that downloads simultaneously, upgrades the software in the single-chip microcomputer.
Human brain is not producing brain wave all the time.Nineteen twenty-four, the psychiatrist Bei Geer of Germany recorded for the first time the brain wave of human brain, the people's that from then on has been born electroencephalogram veritably.This is some spontaneous rhythmic neuroelectricity activities, and its frequency variation scope can be divided into four wave bands between per second 1-30 time, i.e. δ (1-3Hz), θ (4-7Hz), α (8-13Hz), β (14-30Hz).
δ ripple, frequency are per second 1-3 time, when the people is immature at infancy stage or intelligence development, the adult under extremely tired and lethargic state, this wave band can appear.
θ ripple, frequency are per second 4-7 time, the adult when wish suffers setbacks and is depressed and this ripple of psychotic very remarkable.But this ripple is the main component in the electroencephalogram of juvenile (10-17 year).
α ripple, frequency are per second 8-13 time, and average is about 10 times, and it is the basilic rhythm of normal brain electric wave, if the stimulation that does not add, its frequency is quite constant.The people clear-headed, quiet and when closing one's eyes this rhythm and pace of moving things the most obvious, open eyes or when accepting other and stimulating, the α ripple disappears at once.
β ripple, frequency are per second 14-30 time, this ripple occurs when psychentonia with when excited or excited, and when the people woke up with a start from dream, the slow wave rhythm and pace of moving things originally can be substituted by this rhythm and pace of moving things immediately.
Electroencephalogram has become the modern auxiliary examination method of many brain diseasess in current medical circle.The brain wave treatment has been brought into play effective function at migraine, epileptics, insomnia, psychological intervention, spirit conditioning aspects such as (as loosen, reduce pressure).
Human body is under normal physiological status, and the endogenous Opium peptide that opiate receptors is in certain foundation level on.This moment, brain wave was in the wavy attitude of α, because under normal condition, the body and mind energy charge is minimum, and relatively the energy that brain obtained is higher, and running will be quicker, smooth and easy, the intuition acumen, and the activity of brain is active.
If when giving morphine continuously, the cell that contains opiate receptors is found itself to be subjected to the undue burden of morphine-like substance, give endogenous Opium peptidergic neuron by the feedback mechanism mail message, make it stop to go up release Opium peptide, so just need more foreign aid's property morphine to supply the minimizing of the Opium peptide in the brain, the habit-forming essence of drugs that Here it is.
The morphine class material in case stop using, both there be not external morphine generation pharmacological action in the maincenter, there is not endogenous Opium peptide performance physiological action yet, thereby occur a series of withdrawal symptoms in succession: alarmed, irritated anxiety, heart rate are accelerated, insomnia, the pain increased, muscular tremor, vomiting, stomachache, diarrhoea, mydriasis, watery nasal discharge tear, perspiration etc.This moment, the body and mind energy charge of human body was acute, and tired fast, brain wave is in the wavy attitude of excessive β.
Because the frequency and the waveform of brain wave vary with each individual, thus use the brain wave Acquisition Circuit accurately to measure brain wave patient's normal condition under at each patient, with this as the benchmark for the treatment of.When patient's drug addiction is shown effect, gather the brain wave of patient when falling ill in real time, and with the brain wave of normal condition relatively, produce the needed brain wave of inducing of treatment.To induce brain wave to feed back to patient's brain, and by self regulating of intravital physiology of people and pathological information, guide patient's brain wave to recover normal level rapidly, thereby eliminate pathological process, recover physically and mentally healthy.The method therapeutic purposes are clear and definite, non-invasively treating, and effectively directly perceived, index is accurate, thereby the patient is not had any misery and side effect.
The effect formula:
Pathologic wave (brain wave during the drug addiction outbreak)+treatment ripple (inducing brain wave)=normal health brain wave
Therefore: treatment ripple=healthy ripple-pathologic wave
The technical solution that adopts is so for achieving the above object: by single-chip microcomputer Central Control Module 1, signal acquisition module 2, DDS treatment ripple generation module 3, keyboard input module 4, serial port module 5, high-speed SRAM 6 and LCD display module 7 constitute, it is characterized in that: single-chip microcomputer Central Control Module 1 respectively with signal acquisition module 2, DDS treatment ripple generation module 3, keyboard input module 4, serial port module 5, high-speed SRAM 6 links to each other with LCD display module 7, wherein, signal acquisition module 2 is connecting signal electrode 8, and DDS treatment ripple generation module 3 is connecting therapeutic electrode 9;
Single-chip microcomputer Central Control Module 1 is imported normal brain wave data in the high-speed SRAM 6 by transmission, and forms Wave data input DDS treatment ripple generation module 3;
Human-computer interaction module comprises keyboard input module 4, LCD display module 7 and LED light;
Aforesaid drug-detoxifying apparatus based on brain wave biofeedback is characterized in that: signal acquisition module 2 includes signal amplifier, high pass filter, low pass filter and analog-to-digital conversion process device.
Aforesaid drug-detoxifying apparatus based on brain wave biofeedback, it is characterized in that: DDS treatment ripple generation module 3 is made up of signal processing module, DDS waveform synthesis module and D/A converter module, wherein, signal processing module mainly is made of CPLD and high-speed memory SRAM6, DDS waveform synthesis module links to each other with D/A converter module, produce data, be sent to therapeutic electrode 9 by transformator.
Aforesaid drug-detoxifying apparatus based on brain wave biofeedback, it is characterized in that: signal acquisition module 2 links to each other with sampled signal electrode 8, gather normal brain wave data and ill brain wave data by sampled signal electrode 8, and give single-chip microcomputer Central Control Module 1 with normal brain activity electric wave transfer of data, be stored to EEPROM, the normal brain wave data that CPLD will be stored among the EEPROM is read, put into and tell SRAM, the ill brain wave data that collects with sampled signal electrode 8 compares analysis then, obtain the current treatment data that need treatment, DDS waveform synthesis module is with current treatment data, real-time adjusting range of instruction and the phase place sent according to single-chip microcomputer, the final D/A converter module of passing through directly produces the treatment ripple similar to the brain wave height, and being sent to eight pairs of therapeutic electrodes 9 after boosting by transformator, the voltage amplitude of each therapeutic electrode 9 all can carry out independent regulation by resistance.
Aforesaid drug-detoxifying apparatus based on brain wave biofeedback, it is characterized in that: signal electrode 8 and therapeutic electrode 9 have the corresponding electrode district, and the number of electrode is corresponding with electrode district, electrode district has 11, comprise: indifferent electrode G1, G2, the G3 electrode district, left frontal lobe electrode F1 electrode district, left frontal lobe electrode F2 electrode district, left side temporal lobe electrode T1 electrode district, left temporal lobe electrode T2 electrode district, left parietal lobe electrode P1 electrode district, left parietal lobe electrode P2 electrode district, left occipital lobe electrode O1 electrode district, left occipital lobe electrode O2 electrode district, each electrode district of above-mentioned electrode district are provided with each one of sampled signal electrode and therapeutic electrode.
Adopt above-mentioned drug-detoxifying apparatus based on brain wave biofeedback, following advantage arranged:
1. take the lead in proposing being produced by healthy brain wave and ill brain wave the thinking of treatment brain wave, treatment ripple and human body electroencephalogram's wave frequency, amplitude height are consistent, have changed that to treat ripple before single, do not have specific aim, the unconspicuous problem of curative effect.
2. at each routine patient, gather the normal brain activity electric wave of himself, produce and himself corresponding treatment ripple.Be equivalent to have more specific aim for each patient makes the treatment ripple to measure, motivated.
3. the treatment ripple actively induces brain wave to recover normal condition rapidly by the principle of simultaneous resonance.
4. in therapeutic process, has biofeedback mechanism; variation according to patient's brain wave; real-time update treatment ripple; thereby the treatment ripple is changed with the variation that patient's brain wave returns to form; have more specific aim and adaptability; the patient's brain that adequately protects is avoided the injury of over-drastic treatment ripple to brain.
5. adopt hyundai electronics frequency digital synthesis technology (DDS), produces the treatment brain wave consistent, accurately induce the brain wave variation, than mode treatment time shortenings such as simple sine wave, square waves more than one times with patient's brain wave height.
6. the whole process using micro computer is controlled automatically, and therapeutic modality is accurate, has avoided the injury of artificial incorrect operation to brain.
Description of drawings
Fig. 1 is a system block diagram of the present invention;
Fig. 2-1,2-2 are system flow chart of the present invention;
Fig. 3-1 is the preposition difference amplification module of an eeg signal Acquisition Circuit of the present invention schematic diagram;
Fig. 3-2 is an eeg signal Acquisition Circuit bandpass filtering modules block schematic diagram of the present invention;
Fig. 3-3 is an eeg signal Acquisition Circuit power frequency trap module schematic diagram of the present invention;
Fig. 3-4 amplifies ﹠amp for eeg signal Acquisition Circuit of the present invention; AD sampling module schematic diagram;
Fig. 3-5 is eeg signal Acquisition Circuit light-coupled isolation module principle figure of the present invention;
Fig. 4-1 treats ripple signal generating circuit CPLD data processing module schematic diagram for the present invention;
Fig. 4-2 treats ripple signal generating circuit waveform storage list schematic diagram for the present invention;
Fig. 5-1 is a single-chip microcomputer central control circuit serial interface module schematic diagram of the present invention;
Fig. 5-2 is a single-chip microcomputer central control circuit single chip control module schematic diagram of the present invention;
Fig. 5-3 is a single-chip microcomputer central control circuit Keysheet module schematic diagram of the present invention;
Fig. 5-4 is a single-chip microcomputer central control circuit LCD display module schematic diagram of the present invention;
Fig. 5-5 is single-chip microcomputer central control circuit LED light module principle figure of the present invention;
Fig. 5-6 is a single-chip microcomputer central control circuit waveform memory module schematic diagram of the present invention;
Fig. 6 is a human body right hemisphere subregion sketch map;
Fig. 7 is an electrode district distribution schematic diagram of the present invention;
Fig. 8 is a brain wave Acquisition Circuit block diagram of the present invention;
Labelling among the figure: 1-single-chip microcomputer Central Control Module; The 2-signal acquisition module; 3-DDS treatment ripple generation module; The 4-keyboard input module; The 5-serial port module; The 6-high-speed SRAM; The 7-LCD display module; 8-sampled signal electrode; The 9-therapeutic electrode; The 10-PC machine;
The specific embodiment
Understand and enforcement the present invention for the ease of those of ordinary skills, the present invention is described in further detail below in conjunction with the drawings and the specific embodiments.
As shown in Figure 1, the present invention is a kind of drug-detoxifying apparatus based on brain wave biofeedback, constitute by single-chip microcomputer Central Control Module 1, signal acquisition module 2, DDS treatment ripple generation module 3, keyboard input module 4, serial port module 5, high-speed SRAM 6 and LCD display module 7, single-chip microcomputer Central Control Module 1 links to each other with LCD display module 7 with signal acquisition module 2, DDS treatment ripple generation module 3, keyboard input module 4, serial port module 5, high-speed SRAM 6 respectively, wherein, signal acquisition module 2 is connecting signal electrode 8, and DDS treatment ripple generation module 3 is connecting therapeutic electrode 9; Signal acquisition module 2 is carried out ill brain wave data transmission with DDS treatment ripple generation module 3, carries out normal brain activity electric wave transfer of data with single-chip microcomputer Central Control Module 1; Single-chip microcomputer Central Control Module 1 is imported normal brain wave data in the high-speed SRAM 6 by transmission, and forms Wave data input DDS treatment ripple generation module 3; Human-computer interaction module comprises keyboard input module 4, LCD display module 7 and LED light; Serial port module 5 links to each other with PC 10, and single-chip microcomputer Central Control Module 1 is carried out software upgrading and data preservation.
Be depicted as system flow chart of the present invention as Fig. 2-1,2-2, use this drug-detoxifying apparatus based on brain wave biofeedback to carry out the method for drug addiction treatment, may further comprise the steps:
To shown in the 3-5, be eeg signal Acquisition Circuit sketch map as Fig. 3-1, under normal circumstances, the amplitude of brain wave is 5～200 μ V from the crest to the trough, and its frequency mainly concentrates between 0.5～40Hz, also exists different performances in different normal persons.Therefore, the present invention just gathers different brain waves at each patient, thereby obtains different treatment ripples, has high specific aim, and purpose is very clear and definite, and therapeutic effect is just very outstanding.
Because the amplitude of brain wave is very little, so must adopt the differential input low-noise preamplifier of band shielding drive circuit and high cmrr, low variety of way of drifting about to extract bioelectrical signals.Owing to exist powerful 50Hz power frequency interference noise in the middle of our surrounding, enter amplifying circuit in the differential mode mode, in addition filtering just can obtain brain wave accurately, guarantees the effect accuracy of treatment.
Treated signal behind over-sampling circuit, must carry out photoelectricity with the digital circuit of back and isolate, and avoids introducing the interference of back digital circuit to signal acquisition circuit.Data are finally given processor analysis, and brain wave obtains medical treatment.
As shown in Figure 8, be brain wave Acquisition Circuit block diagram, each signal electrode and any one indifferent electrode are formed the difference-mode input signal, and totally eight groups of signals constitute eight passages of signals collecting.
Form preposition differential amplifier circuit by three low noise high-performance amplifier U1, U3, U8, the differential signal that obtains carries out the signal amplification by the instrument amplifier U4 of high cmrr.
The frequency of brain wave mainly concentrates between 0.5～40Hz, for other clutter of filtering, obtains purified brain wave, must carry out filter design.Filter circuit is made up of a high pass filter and a low pass filter.High pass filter design cut-off frequency is 1Hz, and low pass filter design is 40Hz by frequency.
In the eeg signal, exist serious 50Hz power frequency and disturb, must carry out filtering to it specially, adopt the band elimination filter U20 of Burr-Brown company to carry out filtering.
Through filtered eeg signal, send into modulus conversion chip U14 after amplifying through one-level U15 at last and sample.Digital circuit for fear of the back produces unnecessary interference to eeg signal, must adopt optocoupler to isolate.Simultaneously, owing to the present invention relates to the health care technology field, must high request be proposed to level of security, so the part that must contact with the patient is isolated fully with the rear circuit.
So far, the brain wave Acquisition Circuit is all finished.It has eight passages, gathers the brain wave of corresponding each cerebral lobe in the brain, is selected to handle by the CS signal by processor.
People's brain comprises left and right two hemisphere and connects the mid portion of two hemisphere.Interhemispheric dorsal surface respectively has an oblique ditch, is called side and splits.The top that side is split, approximately when the centre of hemisphere, have one by on the step forward brain ditch of below, be called Rolandic fissure.Each hemisphere is divided into four leaves again: the position on splitting with side before the Rolandic fissure is called frontal lobe; Side is split following position, is called temporal lobe; Part on Rolandic fissure splits with side afterwards is called top; After top and the temporal lobe, the part of brain rear end is called occipital lobe on cerebellum.More than each cerebral lobe, all extend, and in each cerebral lobe zone, many little brain ditches arranged respectively to the medial surface of hemisphere and bottom surface, wherein containing various nerve centres, share different tasks.As shown in Figure 6, wherein, frontal lobe is responsible for thinking, plan, and is relevant with the demand and the emotion of individuality; The sensation of top response pain, touch, trial test, temperature, pressure; Temporal lobe is responsible for handling auditory information, and is also relevant with memory and emotion; Occipital lobe is responsible for processing visual information.
When patient's drug addiction was shown effect, the electric wave of each cerebral lobe of brain inside all can change, and therefore will gather respectively the computer of each cerebral lobe.
As shown in Figure 7,
G1, G2, G3: be indifferent electrode, i.e. ground wire.The position is two ear-lobes and middle part, the place ahead, the crown.
F1, F2: be frontal electrode.Be responsible for gathering the brain wave of brain frontal cortex part.
T1, T2: be the temporal lobe electrode.Be responsible for gathering the brain wave of brain temporal lobe part.
P1, P2: be the top electrode.Be responsible for gathering the brain wave of quader part.
O1, O2: be the occipital lobe electrode.Be responsible for gathering the brain wave of brain occipital lobe part.
About each cerebral lobe of half brain all establish an electrode, other has three indifferent electrodes, meter is got 11 electrode districts.
Each electrode district is provided with each one of sampled signal electrode and therapeutic electrode.
When treatment, put on suitable electrode cap to the experimenter, push hair aside, place the electrode area scalp with defat with the cotton ball soaked in alcohol wiping earlier, install then and use SS saline soaked electrode.
,, when the patient is in normal condition (drug addiction remains dormant), obtains the ordinary wave of patient's brain by the sampling electrode, and be stored to EEPROM to shown in the 4-2 as Fig. 4-1 for DDS circuit design part of module sketch map.To obtain ill ripple by the sampling electrode during morbidity, and with the ordinary wave that collects before make comparisons analyze after, produce the treatment ripple similar by modern advanced electronic frequency digital synthesis technology (DDS) to the brain wave height, act on brain, directly suppress psychology and psychological need that the drug addiction outbreak produces.In therapeutic process, continuous acquisition morbid state ripple, real-time update treatment ripple acts on clearly defined objective, with strong points.
The DDS circuit mainly is divided into four parts: signal acquisition module, signal processing module, DDS waveform synthesis module, D/A converter module.
Under patient's normal condition, signal acquisition module is gathered the normal waveform of each cerebral lobe of brain by the sampling electrode, after amplification, filtering, isolation, is transmitted to single-chip microcomputer U19 through CPLD, is stored to eeprom chip IC7.In the therapeutic process, each cerebral lobe morbid state ripple of signal acquisition module continuous acquisition brain after amplification, filtering, isolation, is sent to CPLD and carries out analyzing and processing.
Signal processing module mainly is made of CPLD and external memory storage SRAM.During treatment, CPLD at first will be stored in ordinary wave among the eeprom chip IC7 and read and put into high-speed SRAM chip IC 4, after analyzing with the ill Bob that collects in real time then, obtain the treatment data of current needs.
DDS waveform synthesis module is with current treatment data, real-time adjusting range of instruction and the phase place sent according to single-chip microcomputer, final directly produce the treatment ripple similar, and be sent to eight pairs of therapeutic electrodes after boosting by transformator T1～T8 to the brain wave height by D/A converter module IC1, IC3.The voltage amplitude of each therapeutic electrode all can carry out independent regulation by resistance.
To shown in the 5-6, be single chip machine controlling circuit design module sketch map as Fig. 5-1, single chip machine controlling circuit mainly is made of one-chip computer module, reseting module, serial port module, waveform memory module.
Single-chip microcomputer U19 is the key control unit of this treatment device, and it is the working condition of each several part in the real-time monitoring system, and analyzes the phase place and the amplitude of current treatment ripple, and notice DDS circuit is revised the treatment ripple in real time.Simultaneously, it also will be responsible for mutual between man-machine, switches gathering under ordinary wave and the wavy attitude of treatment, and shows the duty of current treatment device by LCD display U5 and LED light.
The steady operation of reset circuit safeguards system in case detect unusually, is restarted whole system immediately by IC6, and the unstable factor of avoiding unpredictable fault that system is caused also at utmost protects the patient to be hurt in no instance simultaneously.
Serial port module IC5 allows this treatment device and miscellaneous equipment (for example PC) to communicate, and can preserve different patients' various brain wave data by PC, and collection has huge help to clinical data.Simultaneously, can carry out software upgrading to this treatment device, the various functions of real-time update by serial port module.
Waveform memory module IC7 is responsible for the normal brain wave Wave data of store patient under the power-down conditions, gathers a normal brain activity electric wave for each patient and can treat, and the situation of avoiding each treatment need gather the normal brain activity electric wave again occurs.
In addition, in the man machine interface circuit design, human-computer interaction interface mainly comprises button, LCD display and three parts of eight LED lights.
The user can select the work at present pattern by button KEY1 according to different needs, and the KEY2 key selects to begin to gather ordinary wave or begin treatment, and the KEY3 key is for stopping to gather ordinary wave or stopping treatment.
LCD display U5 shows information such as current therapeutic state, treatment wave parameter, brain wave frequency, ill wave parameter in real time, and treatment information comes into plain view, and is convenient to very much the patient and treats adjusting.
Eight LED lights are indicated the duty of eight treatment passages respectively, when unusual, can in time report to the police, and conveniently take correct treatment measure in the very first time.
The present invention uses the brain wave principle of bionics principle, brain science, physical resonance principle, cerebral activity rule and characteristics according to the people, adopt bio information analogue technique, computer technology and electronic technology, ill brain wave in the time of the healthy brain wave of collection patient normal condition and morbidity produces and suppresses the treatment ripple that drug addiction is shown effect.By synchronous therapeutic ripple and E.E.G resonance, the indirect induction brain wave reaches rapidly and the corresponding best brain wave frequency of normal condition; And in therapeutic process, according to the difference of ill ripple, real-time update is treated ripple, thereby more effectively suppress the outbreak of drug addiction.
Claims (7)
1. drug-detoxifying apparatus based on brain wave biofeedback, constitute by single-chip microcomputer Central Control Module (1), signal acquisition module (2), DDS treatment ripple generation module (3), keyboard input module (4), serial port module (5), high-speed SRAM (6) and LCD display module (7), it is characterized in that:
Described single-chip microcomputer Central Control Module (1) links to each other with LCD display module (7) with signal acquisition module (2), DDS treatment ripple generation module (3), keyboard input module (4), serial port module (5), high-speed SRAM (6) respectively, wherein, signal acquisition module (2) is connecting signal electrode (8), and DDS treatment ripple generation module (3) is connecting therapeutic electrode (9);
Described signal acquisition module (2) is carried out ill brain wave data transmission with described DDS treatment ripple generation module (3), carries out normal brain activity electric wave transfer of data with single-chip microcomputer Central Control Module (1);
Described single-chip microcomputer Central Control Module (1) is imported normal brain wave data in the described high-speed SRAM (6) by transmission, and the formation Wave data is imported described DDS treatment ripple generation module (3);
Described human-computer interaction module comprises keyboard input module (4), LCD display module (7) and LED light;
Described serial port module (5) links to each other with PC (10), and single-chip microcomputer Central Control Module (1) is carried out software upgrading and data preservation.
2. drug-detoxifying apparatus based on brain wave biofeedback as claimed in claim 1 is characterized in that: described signal acquisition module (2) includes signal amplifier, high pass filter, low pass filter and analog-to-digital conversion process device.
3. drug-detoxifying apparatus based on brain wave biofeedback as claimed in claim 2, it is characterized in that: described DDS treatment ripple generation module (3) is made up of signal processing module, DDS waveform synthesis module and D/A converter module, wherein, signal processing module mainly is made of CPLD and described high-speed memory SRAM (6), DDS waveform synthesis module links to each other with D/A converter module, produce data, be sent to described therapeutic electrode (9) by transformator.
4. drug-detoxifying apparatus based on brain wave biofeedback as claimed in claim 3, it is characterized in that: described signal acquisition module (2) links to each other with sampled signal electrode (8), gather normal brain wave data and ill brain wave data by sampled signal electrode (8), and give single-chip microcomputer Central Control Module (1) with normal brain activity electric wave transfer of data, be stored to EEPROM, the normal brain wave data that CPLD will be stored among the EEPROM is read, put into and tell SRAM, the ill brain wave data that collects with sampled signal electrode (8) compares analysis then, obtain the current treatment data that need treatment, DDS waveform synthesis module is with current treatment data, real-time adjusting range of instruction and the phase place sent according to single-chip microcomputer, the final D/A converter module of passing through directly produces the treatment ripple similar to the brain wave height, and being sent to eight pairs of therapeutic electrodes (9) after boosting by transformator, the voltage amplitude of each therapeutic electrode (9) all can carry out independent regulation by resistance.
5. as the described drug-detoxifying apparatus based on brain wave biofeedback of one of claim 1-4, it is characterized in that: described signal electrode (8) and therapeutic electrode (9) have the corresponding electrode district, and the number of electrode is corresponding with electrode district, described electrode district has 11, comprise: indifferent electrode G1, G2, the G3 electrode district, left frontal lobe electrode F1 electrode district, left frontal lobe electrode F2 electrode district, left side temporal lobe electrode T1 electrode district, left temporal lobe electrode T2 electrode district, left parietal lobe electrode P1 electrode district, left parietal lobe electrode P2 electrode district, left occipital lobe electrode O1 electrode district, left occipital lobe electrode O2 electrode district, each electrode district of above-mentioned electrode district are provided with each one of sampled signal electrode and therapeutic electrode.
6. method of using drug-detoxifying apparatus based on brain wave biofeedback as claimed in claim 1 to carry out drug addiction treatment may further comprise the steps:
Step 1, equipment is carried out initialization apparatus, and judge whether to carry out drug addiction treatment;
Step 2, if step 1 is judged need be treated, then further judge to be in acquisition state or therapeutic state;
Step 3, if step 2 be judged as acquisition state, then begin acquired signal, the signal of collection is the normal brain activity electric wave signal and judges whether this end signal collection;
Step 4, if step 3 is judged signal acquisition process to be finished, the normal brain activity electric wave is stored among the EEPROM, and finishes the laggard therapeutic state of going in storage;
Step 5,, step 2 enters therapeutic state after therapeutic state or step 4 finish if being judged as, then begin to treat, comprise the ill brain wave data of collection, analyze to produce and treat wave datum, adjusting waveform, DDS generation treatment ripple signal, after said process finishes, judge whether to finish therapeutic state.
7. drug addiction treatment method as claimed in claim 6, it is characterized in that: when wherein the signal of gathering in the step 3 remains dormant for be in normal condition or drug addiction as the patient, obtain the ordinary wave of patient's brain by sampled signal electrode (8), and be stored to EEPROM; Gathering ill brain wave data in the above-mentioned steps five is when patient's morbidity or drug addiction outbreak, obtain ill ripple by sampled signal electrode (8), and with the ordinary wave that collects before make comparisons analyze after, produce the treatment ripple similar by modern advanced electronic frequency digital synthesis technology (DDS) to the brain wave height, act on brain, directly suppress psychology and psychological need that the drug addiction outbreak produces; In therapeutic process, continuous acquisition morbid state ripple, real-time update treatment ripple.
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