CN101919938A - Traditional Chinese medicine preparation for treating thrombocytopenia - Google Patents

Traditional Chinese medicine preparation for treating thrombocytopenia Download PDF

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Publication number
CN101919938A
CN101919938A CN2010101874809A CN201010187480A CN101919938A CN 101919938 A CN101919938 A CN 101919938A CN 2010101874809 A CN2010101874809 A CN 2010101874809A CN 201010187480 A CN201010187480 A CN 201010187480A CN 101919938 A CN101919938 A CN 101919938A
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China
Prior art keywords
radix
herba
thrombocytopenia
chinese medicine
medicine preparation
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CN2010101874809A
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Chinese (zh)
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杨淑环
彭润海
赵文海
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Individual
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Priority to CN2010101874809A priority Critical patent/CN101919938A/en
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating thrombocytopenia, which is prepared from Chinese patent medicines of callicarpa undiflora, spikemoss, glabrous sarcandra herb, gromwell, madder, setose thistle, common cephalanoplos herb and natural indigo. The traditional Chinese medicine preparation has a unique effect on thrombocytopenia treatment, and has an especially better thrombocytopenia treatment effect under the condition of clinically combined therapy of Chinese and Western medicine.

Description

A kind of Chinese medicine preparation for the treatment of thrombocytopenia
Technical field the present invention relates to a kind of Chinese medicine preparation for the treatment of thrombocytopenia.
The background technology thrombocytopenia causes tampon to form bad and hemorrhage causing owing to platelet counts reduces.Thrombocytopenia can cause typically hemorrhage, as multiple ecchymosis, is most commonly in shank; Or be subjected to little the being dispersed in property ecchymosis of position appearance of microtrauma; Mucosal bleeding (epistaxis, gastrointestinal tract, urogenital tract and vaginal hemorrhage); Bleed profusely after the operation.But gastrointestinal tract is bled profusely and central nervous system's internal hemorrhage severe patient threat to life.Western medical treatment thrombocytopenia choice drug is a hormone at present, taking the back platelet generally can raise, but the side effect of hormone is very big, in increased platelets counts, can increase many new diseases again, as central obesity, hypertension, diabetes, osteoporosis etc., and after the hormone decrement, platelet can reduce again, still can show effect repeatedly after the drug withdrawal.The feasible splenectomy of thrombocytopenia severe patient, but surgical risk is big, and patient itself is difficult to accept.Spleen is the human immunity organ, causes the patient immune function low after cutting spleen, causes severe infections easily, gives patient body and brings misery mentally.
Motherland's medical science has been carried out a large amount of research to the treatment thrombocytopenia, has invented the medicine of many treatment thrombocytopenia.It as the patent No. 200710014841 patent, the thrombocytopenic medicine of a kind of treatment is disclosed, it is formulated by Herba Agrimoniae, Herba Epimedii, the Radix Astragali, charred RADIX RUBIAE, Radix Notoginseng powder, its malignant tumor to blood system is produced effects better, both increased platelets counts was different from present the Western medicine preparation of increased platelets counts merely again.And for example the patent No. is the patent of CN200910094942.X, and a kind of medicine for the treatment of thrombocytopenic purpura is provided, and it is made up of Rhizoma Smilacis Glabrae, Flos Lonicerae, Radix Arnebiae (Radix Lithospermi), Radix Rehmanniae, Cortex Mori, Concha Ostreae, Caulis et folium clerodendri bungei, Radix Scutellariae, Periostracum Cicadae.It has clearing away heat and cooling blood, hemostasis dissipating rashes, promoting blood circulation to remove blood stasis, microcirculation improvement, dredging the meridian, effects such as eliminate pain, and do not add any chemicals, nontoxic to human body, taking convenience, energy enhancing body resistance and immunity are removed the patient suffering, and therapeutic effect is remarkable.The patent No. is the patent of CN01106719.5 for another example, a kind of medicine for the treatment of idiopathic thrombocytopenic purpura is disclosed, form by Rhizoma Smilacis Glabrae, Radix Scutellariae, Radix Glycyrrhizae, the Radix Rehmanniae, Cortex Moutan, Herba Cirsii, Rhizoma Imperatae compatibility, this medicine can suppress antiplatelet antibody effectively, make platelet go back up to normal value, for the abortion in first trimester patient who causes owing to platelet antibody good therapeutical effect is arranged also simultaneously, the characteristics of this medicine are not have taboo, toxic and side effects is little, curative effect is reliable, taking convenience, effectively cure rate reaches 95%.
It is simple that summary of the invention the purpose of this invention is to provide a kind of prescription, with low cost, to treating the new medicine preparation that thrombocytopenia has unique curative effect.The technical scheme that the present invention takes is: based on the research basis of the traditional Chinese medical science to medicine, filter out the Chinese medicine patent medicine that Folium Callicarpae Formosanae, Herba Selaginellae, Herba Sarcandrae, Radix Arnebiae (Radix Lithospermi), Radix Rubiae, Radix Cirsii Japonici, Herba Cirsii and Indigo Naturalis eight flavors have treatment thrombocytopenia effect, a kind of Chinese medicine preparation is made in the processing training.
The medicine that the present invention screened is made (consumption is a weight portion) by following component:
Folium Callicarpae Formosanae 20-40 Herba Selaginellae 15-35 Herba Sarcandrae 10-30 Radix Arnebiae (Radix Lithospermi) 15-25
Radix Rubiae 10-25 Radix Cirsii Japonici 25-45 Herba Cirsii 20-40 Indigo Naturalis 5-10
Preparing pharmaceutical formulation preferred weight of the present invention (part) ratio range is:
Folium Callicarpae Formosanae 25-35 Herba Selaginellae 20-30 Herba Sarcandrae 15-25 Radix Arnebiae (Radix Lithospermi) 15-20
Radix Rubiae 15-20 Radix Cirsii Japonici 30-40 Herba Cirsii 25-35 Indigo Naturalis 6-8
The optimum weight of medicine of the present invention (part) proportioning is:
Folium Callicarpae Formosanae 30 Herba Selaginellaes 25 Herba Sarcandraes 20 Radix Arnebiae (Radix Lithospermi)s 18
Radix Rubiae 18 Radix Cirsii Japonicis 35 Herba Cirsiis 30 Indigo Naturaliss 7
Above-mentioned each component is made medicine processing method of the present invention is:
The first step is carried out the pretreatment of crude drug: Folium Callicarpae Formosanae, Herba Selaginellae, Herba Sarcandrae, Radix Arnebiae (Radix Lithospermi), Radix Rubiae, Radix Cirsii Japonici, Herba Cirsii and Indigo Naturalis eight flavor medicines carry out sterilizing-drying.
The second step grinding and processing: Folium Callicarpae Formosanae, Herba Selaginellae, Herba Sarcandrae, Radix Arnebiae (Radix Lithospermi), Radix Rubiae, Radix Cirsii Japonici, Herba Cirsii and Indigo Naturalis are ground into 100 order fine powders.
The 3rd step preparation finished product: with above-mentioned fine powder facing-up, sieve, mixing, pharmaceutical methods is made capsule, the watered pill or tablet routinely.
The instructions of taking of medicine of the present invention is: 3 of oral capsules, the watered pill 10 balls, 2 times on the one.
Each drug component that the present invention selects for use meets state-promulgated pharmacopoeia regulation, and prescription is simple, and is with low cost, and the treatment thrombocytopenia is had unique curative effect, and it is better particularly to carry out therapy of combining Chinese and Western medicine thrombocytopenia curative effect clinically.
The specific embodiment takes by weighing raw material (kilogram) by following proportioning:
Folium Callicarpae Formosanae 30 Herba Selaginellaes 25 Herba Sarcandraes 20 Radix Arnebiae (Radix Lithospermi)s 18
Radix Rubiae 18 Radix Cirsii Japonicis 35 Herba Cirsiis 30 Indigo Naturaliss 7
To be crushed to 100 orders with the Chinese herbal medicine high speed disintegrator behind each component drug sterilizing-drying, fully mixing incapsulates, and every heavy 0.25~0.3 gram is packed 50 every bag with the polyethylene film plastic packaging machine at last.

Claims (5)

1. a Chinese medicine preparation for the treatment of thrombocytopenia is characterized in that it is that preparation of raw material forms with Chinese medicine patent medicine Folium Callicarpae Formosanae, Herba Selaginellae, Herba Sarcandrae, Radix Arnebiae (Radix Lithospermi), Radix Rubiae, Radix Cirsii Japonici, Herba Cirsii and Indigo Naturalis.
2. according to claims 1 described a kind of Chinese medicine preparation for the treatment of thrombocytopenia, it is characterized in that it is made by following weight proportioning raw material:
Folium Callicarpae Formosanae 20-40 Herba Selaginellae 15-35 Herba Sarcandrae 10-30 Radix Arnebiae (Radix Lithospermi) 15-25
Radix Rubiae 10-25 Radix Cirsii Japonici 25-45 Herba Cirsii 20-40 Indigo Naturalis 5-10.
3. a kind of Chinese medicine preparation for the treatment of thrombocytopenia according to claim 1 is characterized in that its optimum ratio is:
Folium Callicarpae Formosanae 25-35 Herba Selaginellae 20-30 Herba Sarcandrae 15-25 Radix Arnebiae (Radix Lithospermi) 15-20
Radix Rubiae 15-20 Radix Cirsii Japonici 30-40 Herba Cirsii 25-35 Indigo Naturalis 6-8.
4. according to claims 1 described a kind of Chinese medicine preparation for the treatment of thrombocytopenia, it is characterized in that its best proportioning is:
Folium Callicarpae Formosanae 30 Herba Selaginellaes 25 Herba Sarcandraes 20 Radix Arnebiae (Radix Lithospermi)s 18
Radix Rubiae 18 Radix Cirsii Japonicis 35 Herba Cirsiis 30 Indigo Naturaliss 7.
5. according to claims 1,2,3 or 4 described a kind of Chinese medicine preparation for the treatment of thrombocytopenia, it is characterized in that described dosage form is capsule, the watered pill or tablet.
CN2010101874809A 2010-05-18 2010-05-18 Traditional Chinese medicine preparation for treating thrombocytopenia Pending CN101919938A (en)

Priority Applications (1)

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CN2010101874809A CN101919938A (en) 2010-05-18 2010-05-18 Traditional Chinese medicine preparation for treating thrombocytopenia

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CN2010101874809A CN101919938A (en) 2010-05-18 2010-05-18 Traditional Chinese medicine preparation for treating thrombocytopenia

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103054976A (en) * 2011-10-21 2013-04-24 上海中医药大学 Chinese medicinal composition for treating thrombopenia as well as preparation method and application of composition
CN105168613A (en) * 2015-09-02 2015-12-23 文波 Traditional Chinese medicine preparation for treating leukemia at emergency stage

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1689615A (en) * 2004-04-21 2005-11-02 范崔生 Bleeding arresting Chinese medicinal composition and its preparation method
CN101244214A (en) * 2008-03-24 2008-08-20 王平 Method of preparing Chinese medicine for treating idiopathic thromboeytopenic purpura idiopathic thromboeytopenic purpura

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1689615A (en) * 2004-04-21 2005-11-02 范崔生 Bleeding arresting Chinese medicinal composition and its preparation method
CN101244214A (en) * 2008-03-24 2008-08-20 王平 Method of preparing Chinese medicine for treating idiopathic thromboeytopenic purpura idiopathic thromboeytopenic purpura

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
富琦: "芪龙调血方治疗免疫性血小板减少性紫癜疗效与机制研究", 《北京中医药大学博士研究生学位论文》 *
素琳等: "紫珠止血作用的实验研究", 《贵阳医学院学报》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103054976A (en) * 2011-10-21 2013-04-24 上海中医药大学 Chinese medicinal composition for treating thrombopenia as well as preparation method and application of composition
CN105168613A (en) * 2015-09-02 2015-12-23 文波 Traditional Chinese medicine preparation for treating leukemia at emergency stage

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Application publication date: 20101222