CN101908864B - Signal acquisition processing circuit for digital brain electrical activity mapping instrument - Google Patents
Signal acquisition processing circuit for digital brain electrical activity mapping instrument Download PDFInfo
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- CN101908864B CN101908864B CN2010102549104A CN201010254910A CN101908864B CN 101908864 B CN101908864 B CN 101908864B CN 2010102549104 A CN2010102549104 A CN 2010102549104A CN 201010254910 A CN201010254910 A CN 201010254910A CN 101908864 B CN101908864 B CN 101908864B
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Abstract
The invention relates to a signal acquisition processing circuit for a digital brain electrical activity mapping instrument. From signal acquisition input, the signal acquisition processing circuit comprises a follow low-pass filter circuit, a difference amplification circuit, a voltage amplification circuit, a 50Hz power frequency trap circuit, a secondary operation amplification circuit, a second-order active low-pass filter circuit and an A/D conversion circuit which are connected in sequence, wherein the A/D conversion circuit is connected with a computer with analyzing software through an optical isolation circuit. The signal acquisition processing circuit has the beneficial effects that the input impedance can reach over 10 megohms so as to improve the signal acquisition sensitivity; various filter circuits are adopted in signal processing, so that the common-mode interference is effectively inhibited, and the equipment working stability can be improved.
Description
Technical field
The present invention relates to Medical Devices, relate in particular to a kind of signal acquisition processing circuit for digital brain electrical activity mapping instrument, built-in multistage amplification of this circuit and multiple-stage filtering are used isolation technology, suppress common mode disturbances effectively.
Background technology
Digital brain electrical activity mapping instrument is a kind of no wound, and the medical instrument of continuous monitoring patient brain wave has become the conventional configuration device of hospital's midbrain disease examination and monitoring; Also be widely used in various mobile monitorings and sleep monitoring outside the hospital, in the diagnosis and treatment process of epilepsy, tumour and brain trauma, play a significant role; Because human body is a high internal resistance signal source; Internal resistance can reach tens kilo-ohms and even hundreds of kilo-ohm, and its internal impedance both had been easy to change, and is might each branch road uneven; Therefore present equipment is disturbed easily, and stability is bad.
Summary of the invention
The objective of the invention is to propose a kind of signal acquisition processing circuit for digital brain electrical activity mapping instrument technical scheme; This scheme adopts follow circuit at input; Improved input impedance to more than 10 megohms; On signal processing, adopt various filter circuits, suppress common mode disturbances effectively, improved the stability of equipment work.
To achieve these goals; Technical scheme of the present invention is; A kind of signal acquisition processing circuit for digital brain electrical activity mapping instrument; The circuit that begins to be linked in sequence from the signals collecting input comprises, follows low-pass filter circuit, differential amplifier circuit, voltage amplifier circuit, 50 Hz power frequency trap circuits, secondary operational amplification circuit, second order active low-pass filter circuit, A/D change-over circuit to the computer that has analysis software; Wherein, Saidly follow that low-pass filter circuit is formed two-stage π type filter circuit by resistance and electric capacity and the operational amplifier follow circuit is formed; The multiplication factor of said differential amplifier circuit is 8 to 12 times; The multiplication factor of said voltage amplifier circuit is 28 to 33 times, is provided with photoelectric isolating circuit between said A/D change-over circuit and the computer.
Said two-stage π type filter circuit comprises resistance R 1, R2, capacitor C 1, C2, C3, and said R1 one end connects the signal input, and the R1 other end is connected with R2 one end; The R2 other end connects the input of follow circuit, capacitor C 1 one termination analog electrical seedbeds, and the C1 other end is connected on the link of resistance R 1 and signal input; C2 one termination analog electrical seedbed; The C2 other end is connected on R1 and the node that R2 connects, C3 one termination analog electrical seedbed, and the C3 other end is connected on R2 and the node that follow circuit is connected; The resistance value of wherein said R1 and R2 be respectively 10K ohm to 30K ohm, the capacitance of said C1 and C2 is respectively 20PF to 30PF, the capacitance of said C3 is 50PF to 100PF.
Said 50 Hz power frequency trap circuits are made up of double T rc filter circuit and operational amplifier follow circuit U1, the U2 that resistance R 3, R4, R5, capacitor C 4, C5, C6 form; Said R3, R4 series connection, said C4, C5 series connection, the R3 of series connection, R4 and the C4 that connects, C5 parallel connection; R3, R4 are connected the signal input with an end of C4, C5 parallel connection; The other end of parallel connection connects the input of follow circuit U1, and C4, C5 series connection node connect resistance R 5 one ends, and R3, R4 series connection node connect capacitor C 6 one ends; The R5 other end and the C6 other end link together and are connected to the output of follow circuit U2; The output of follow circuit U1 is signal output, and the output of follow circuit U1 simultaneously connects output divider resistance R6 and R7, and the dividing potential drop node of R6 and R7 is connected the input of follow circuit U2.
The capacitance of said capacitor C 4 and C5 is respectively 0.047uF, and the resistance value of resistance R 3 and R4 is respectively 68K ohm, and the capacitance of capacitor C 6 is 0.047uF * 2, and the resistance value of resistance R 5 is 68K ohm/2, and the resistance value ratio of resistance R 6 and R7 is 1.5 to 10.
Said second order active low-pass filter circuit is made up of resistance R 8, R9, capacitor C 7, C8 and operational amplifier follow circuit U3; Said R8 and R9 series connection, R8 after the series connection and the input of R9 one termination signal, the other end connects the input of follow circuit U3; The output of follow circuit U3 is signal output; Be connected capacitor C 8 between R8 and R9 series connection node and the output that meets follow circuit U3, be connected capacitor C 7 between the input of follow circuit U3 and the simulation ground, the resistance value of said resistance R 8 and R9 is respectively 22K ohm; The capacitance of said C7 is 0.1uF, and the capacitance of said C8 is 0.22uF.
Said differential amplifier circuit is that model is the instrumentation amplifier of AD620.
The invention has the beneficial effects as follows that the input impedance of signal acquisition processing circuit for digital brain electrical activity mapping instrument of the present invention can reach more than 10 megohms, improved the collection sensitivity of signal; On signal processing, adopt various filter circuits, suppress common mode disturbances effectively, improved the stability of equipment work.
Below in conjunction with accompanying drawing and embodiment the present invention is done further detailed description.
Description of drawings
Fig. 1 is that circuit of the present invention connects logic diagram;
Fig. 2 is the two poles of the earth of the present invention π type filter circuits;
Fig. 3 is the present invention's 50 Hz power frequency trap circuits;
Fig. 4 is a second order active low-pass filter circuit of the present invention.
Embodiment
A kind of signal acquisition processing circuit for digital brain electrical activity mapping instrument embodiment; Said signal acquisition processing circuit comprises from the circuit that the signals collecting input begins to be linked in sequence; Follow low-pass filter circuit 1, differential amplifier circuit 2, voltage amplifier circuit 3,50 Hz power frequency trap circuits 4, secondary operational amplification circuit 5, second order active low-pass filter circuit 6, A/D change-over circuit 7, the A/D change-over circuit connects the computer 9 that has analysis software through photoelectric isolating circuit 8; Wherein, That the A/D change-over circuit adopts is the little process chip MSP430F147 that has the A/D translation function, and described voltage amplifier circuit adopts operational amplifier TLC2254CDR or LF444, makes when low frequency, also to have very high input impedance; Thereby has stronger AC coupled ability; Said secondary operational amplification circuit is the general-purpose operation amplifying circuit, saidly follows that low-pass filter circuit is formed two-stage π type filter circuit by resistance and electric capacity and the operational amplifier follow circuit is formed, and said differential amplifier circuit is an instrumentation amplifier; Embodiment has utilized the relation of instrumentation amplifier common-mode rejection ratio and gain; Can under the situation that suppresses the direct current interference, higher common-mode rejection ratio be provided, the multiplication factor of differential amplifier circuit is 8 to 12 times, and the multiplication factor of said voltage amplifier circuit is 28 to 33 times; Be provided with photoelectric isolating circuit between said A/D change-over circuit and the computer, what said photoelectric isolating circuit adopted is that model is the photoelectric isolating circuit of 6N137.
Follow two-stage π type filter circuit in the low-pass filter circuit undertaking suppress the wide spectrum noise and before ADC anti-aliasing dual role, the both requires the passband of low pass filter smooth as far as possible, The faster the better for the speed of roll-offing, so that obtain higher signal to noise ratio.Because the input signal of following low-pass filter circuit derives from the cerebral cortex of human body; Human body is a high internal resistance signal source; Internal resistance can reach tens kilo-ohms and even hundreds of kilo-ohm, and its internal impedance both had been easy to change, and is might each branch road uneven; So the operational amplifier follow circuit of following in the low-pass filter circuit has been realized the above input impedance of 10 megohms.
Said two-stage π type filter circuit comprises resistance R 1, R2, capacitor C 1, C2, C3, and said R1 one end connects the signal input, and the R1 other end is connected with R2 one end; The R2 other end connects the input of follow circuit, capacitor C 1 one termination analog electrical seedbeds, and the C1 other end is connected on the link of resistance R 1 and signal input; C2 one termination analog electrical seedbed; The C2 other end is connected on R1 and the node that R2 connects, C3 one termination analog electrical seedbed, and the C3 other end is connected on R2 and the node that follow circuit is connected; The resistance value of wherein said R1 and R2 is respectively that 10K ohm is to 30K ohm; The capacitance of said C1 and C2 is respectively 20PF to 30PF; The capacitance of present embodiment C1 and C2 is respectively 22PF, and the capacitance of said C3 is 50PF to 100PF, and the capacitance of present embodiment C3 is 62PF; Present embodiment is connected with discharge tube TVS between node that R1 connects with R2 and simulation ground, discharge tube TVS is in order to prevent too high signal input.
Said 50 Hz power frequency trap circuits are made up of double T rc filter circuit and operational amplifier follow circuit U1, the U2 that resistance R 3, R4, R5, capacitor C 4, C5, C6 form; Said R3, R4 series connection, said C4, C5 series connection, the R3 of series connection, R4 and the C4 that connects, C5 parallel connection; R3, R4 are connected the signal input with an end of C4, C5 parallel connection; The other end of parallel connection connects the input of follow circuit U1, and C4, C5 series connection node connect resistance R 5 one ends, and R3, R4 series connection node connect capacitor C 6 one ends; The R5 other end and the C6 other end link together and are connected to the output of follow circuit U2; The output of follow circuit U1 is signal output, and the output of follow circuit U1 simultaneously connects output divider resistance R6 and R7, and the dividing potential drop node of R6 and R7 is connected the input of follow circuit U2.
The capacitance of said capacitor C 4 and C5 is respectively 0.047uF, and the resistance value of resistance R 3 and R4 is respectively 68K ohm, and the capacitance of capacitor C 6 is 0.047uF * 2, and the resistance value of resistance R 5 is 68K ohm/2, and the resistance value ratio of resistance R 6 and R7 is 1.5 to 10.
Said second order active low-pass filter circuit is made up of resistance R 8, R9, capacitor C 7, C8 and operational amplifier follow circuit U3; Said R8 and R9 series connection, R8 after the series connection and the input of R9 one termination signal, the other end connects the input of follow circuit U3; The output of follow circuit U3 is signal output; Be connected capacitor C 8 between R8 and R9 series connection node and the output that meets follow circuit U3, be connected capacitor C 7 between the input of follow circuit U3 and the simulation ground, the resistance value of said resistance R 8 and R9 is respectively 22K ohm; The capacitance of said C7 is 0.1uF, and the capacitance of said C8 is 0.22uF.
Said differential amplifier circuit is that model is the instrumentation amplifier of AD620.
Claims (8)
1. signal acquisition processing circuit for digital brain electrical activity mapping instrument; It is characterized in that; Said signal acquisition processing circuit comprises from the circuit that signals collecting input begins to be linked in sequence, the above input impedance of 10 megohms follow low-pass filter circuit, differential amplifier circuit, voltage amplifier circuit, 50 Hz power frequency trap circuits, secondary operational amplification circuit, second order active low-pass filter circuit, A/D change-over circuit to the computer that has analysis software; Saidly follow that low-pass filter circuit is formed two-stage π type filter circuit by resistance and electric capacity and the operational amplifier follow circuit is formed; The multiplication factor of said differential amplifier circuit is 8 to 12 times; The multiplication factor of said voltage amplifier circuit is 28 to 33 times, is provided with photoelectric isolating circuit between said A/D change-over circuit and the computer.
2. signal acquisition processing circuit for digital brain electrical activity mapping instrument according to claim 1 is characterized in that, said two-stage π type filter circuit comprises resistance R 1, R2, capacitor C 1, C2, C3; Said R1 one end connects the signal input, and the R1 other end is connected with R2 one end, and the R2 other end connects the input of follow circuit; Capacitor C 1 one termination analog electrical seedbeds; The C1 other end is connected on the link of resistance R 1 and signal input, C2 one termination analog electrical seedbed, and the C2 other end is connected on R1 and the node that R2 connects; C3 one termination analog electrical seedbed, the C3 other end are connected on R2 and the node that follow circuit is connected; The resistance value of wherein said R1 and R2 be respectively 10K ohm to 30K ohm, the capacitance of said C1 and C2 is respectively 20PF to 30PF, the capacitance of said C3 is 50PF to 100PF.
3. signal acquisition processing circuit for digital brain electrical activity mapping instrument according to claim 2 is characterized in that, is connected with discharge tube between node that said R1 connects with R2 and the simulation ground.
4. signal acquisition processing circuit for digital brain electrical activity mapping instrument according to claim 1; It is characterized in that said 50 Hz power frequency trap circuits are made up of double T rc filter circuit and operational amplifier follow circuit U1, the U2 that resistance R 3, R4, R5, capacitor C 4, C5, C6 form, said R3, R4 series connection; Said C4, C5 series connection; R3, the R4 of series connection and the C4 that connects, C5 parallel connection, R3, R4 are connected the signal input with an end of C4, C5 parallel connection, and the other end of parallel connection connects the input of follow circuit U1; C4, C5 series connection node connect resistance R 5 one ends; R3, R4 series connection node connect capacitor C 6 one ends, and the R5 other end and the C6 other end link together and be connected to the output of follow circuit U2, and the output of follow circuit U1 is signal output; The output of follow circuit U1 simultaneously connects output divider resistance R6 and R7, and the dividing potential drop node of R6 and R7 is connected the input of follow circuit U2.
5. signal acquisition processing circuit for digital brain electrical activity mapping instrument according to claim 4; It is characterized in that; The capacitance of said capacitor C 4 and C5 is respectively 0.047uF, and the resistance value of resistance R 3 and R4 is respectively 68K ohm, and the capacitance of capacitor C 6 is 0.047uF * 2; The resistance value of resistance R 5 is 68K ohm/2, and the resistance value ratio of resistance R 6 and R7 is 1.5 to 10.
6. signal acquisition processing circuit for digital brain electrical activity mapping instrument according to claim 1; It is characterized in that; Said second order active low-pass filter circuit is made up of resistance R 8, R9, capacitor C 7, C8 and operational amplifier follow circuit U3, said R8 and R9 series connection, R8 after the series connection and the input of R9 one termination signal; The other end connects the input of follow circuit U3; The output of follow circuit U3 is signal output, is connected capacitor C 8 between R8 and R9 series connection node and the output that meets follow circuit U3, and the input of follow circuit U3 is connected capacitor C 7 with simulating between the ground.
7. signal acquisition processing circuit for digital brain electrical activity mapping instrument according to claim 6 is characterized in that, the resistance value of said resistance R 8 and R9 is respectively 22K ohm, and the capacitance of said C7 is 0.1uF, and the capacitance of said C8 is 0.22uF.
8. signal acquisition processing circuit for digital brain electrical activity mapping instrument according to claim 1 is characterized in that, said differential amplifier circuit is that model is the instrumentation amplifier of AD620.
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| CN102068251B (en) * | 2011-01-24 | 2012-03-21 | 北京航空航天大学 | Implantable front-end acquisition device for brain electrical signal and manufacturing method thereof |
| CN103532518A (en) * | 2012-07-03 | 2014-01-22 | 四川蓝讯宝迩电子科技有限公司 | DC coupling low-pass RC active filter |
| CN104117144B (en) * | 2014-07-29 | 2016-04-13 | 成都千里电子设备有限公司 | Electrode slice gear output control circuit |
| CN104218944A (en) * | 2014-09-26 | 2014-12-17 | 永济新时速电机电器有限责任公司 | Machine telegraph signal conditioning circuit for electric propulsive ship |
| CN105943034A (en) * | 2016-05-31 | 2016-09-21 | 周立民 | Instrument capable of generating medulla oblongata and brainstem electrographs and electrical activity mapping and using method |
| CN109864710A (en) * | 2019-02-27 | 2019-06-11 | 江南大学 | A kind of nightwear with sleep detection function |
| CN114123517A (en) * | 2022-01-24 | 2022-03-01 | 国网山东省电力公司新泰市供电公司 | Power distribution automation and distribution network automation comprehensive control system and method |
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| CN2753289Y (en) * | 2004-11-22 | 2006-01-25 | 中国科学院心理研究所 | Electroencephalo signal amplifier |
| CN2865563Y (en) * | 2005-04-01 | 2007-02-07 | 秦皇岛市康泰医学系统有限公司 | Electroencephalogram collecting instrument |
| CN101433461A (en) * | 2008-12-04 | 2009-05-20 | 上海大学 | Detection circuit for high-performance brain electrical signal of brain-machine interface |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN2753289Y (en) * | 2004-11-22 | 2006-01-25 | 中国科学院心理研究所 | Electroencephalo signal amplifier |
| CN2865563Y (en) * | 2005-04-01 | 2007-02-07 | 秦皇岛市康泰医学系统有限公司 | Electroencephalogram collecting instrument |
| CN101433461A (en) * | 2008-12-04 | 2009-05-20 | 上海大学 | Detection circuit for high-performance brain electrical signal of brain-machine interface |
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Address after: Qin 066004 West Street in Hebei province Qinhuangdao City Economic and Technological Development Zone No. 112 Patentee after: Kangtai medical system (Qinhuangdao) Limited by Share Ltd Address before: 066004 Qinhuangdao city of Hebei province the Yellow River Development Zone West Road No. 24 Patentee before: Qinhuangdao Contec Medical Systems Co.,Ltd. |