CN101904915B - Chinese medicinal composition for promoting fast recovery of burn - Google Patents
Chinese medicinal composition for promoting fast recovery of burn Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for promoting the fast recovery of burn. The Chinese medicinal composition is prepared from the following components in part by weight: 0.01 to 0.5 part of gibberellins, 50 to 150 parts of mahonia fortunei, 30 to 70 parts of peach gum, 50 to 150 parts of giant knotweed, 0.5 to 2 parts of borneol, 0.5 to 2 parts of artificial bezoar and 30 to 70 parts of peppermint oil. The Chinese medicinal composition has the advantages that: (1) through strict theoretical argumentation and abundant experimental screening, plant growth hormone gibberellins (920) are creatively added on the basis of six traditional Chinese medicines, so that the formula is simplified, the quality problem during the production links is effectively controlled, and fast healing and recovery of skin tissues in the burn wound surface are more effectively promoted; (2) the Chinese medicinal composition has the characteristics of convenient preparation, low cost, obvious curative effect and low side effect; and (3) the Chinese medicinal composition can be prepared into various external preparations, which brings great convenience to the treatment of the patients.
Description
Technical field
The invention belongs to Chinese medicine composition, relate in particular to a kind of Chinese medicine composition that is used to promote fast recovery of burn.
Background technology
Burn is that many factors such as physics, chemistry, radiation act on a kind of extremely complicated traumatic disease that body causes; Its sickness rate is in rising trend; According to the investigation statistics of the Third Military Medical University's interrelated data and the U.S., l ten thousand people burn is arranged approximately among the annual million people.The medicine of existing treatment burn is varied, and one type is to be medicine and the treatment measure that main treatment is burnt with the doctor trained in Western medicine, and one type is to be main treatment route with Chinese medicine.The western medical treatment burn does not advocate to hinder the face medicine-feeding, is main with innerlich anwenden mainly, hinders face and directly handles with any medicine hardly.The method seems science, and in fact effect is not very desirable, and cost is extremely expensive.And China's Traditional Chinese medical theory has oneself opinion and treatment measure for the treatment burn; Promptly wound surface is left intact (only blister is discharged water to handle and get final product) medicine-feeding immediately, pain relieving rapidly; Alleviate the pain of injury; Fully stimulate the regeneration capacity of human body cell through external used medicine, impel muscular tissue growth fast again, thereby reach the therapeutic effect of short-term recovery from illness.
At present, it is various to apply to clinical Chinese medicine burn prescription, as: JINGWANHONG RUANGAO, ZIHUA SHAOSHANGGAO, Chinese medicine MEIBAO SHIRUN SHAOSHANG GAO, Chinese medicine ointment for decrustation after etc.; Though above-mentioned listing prescription has curative effect preferably when the treatment burn, brought into play the peculiar advantage of treatment by Chinese herbs burn; Yet; The Chinese medicine kind that contains in its most prescription is more, and as containing Chinese medicine ingredients in the JINGWANHONG RUANGAO prescription up to 33 kinds, the ZIHUA SHAOSHANGGAO prescription contains nearly 10 kinds of Chinese medicine ingredients; Though so many Chinese medicine ingredients can improve the curative effect of prescription, certainly will also can bring influence to the preparation of prescription and the quality control of medicine.Shortcomings such as in addition, at present many Chinese prescriptions of development also exist effective course of treatment long, and need change dressings repeatedly every day, and misery is big when changing dressings certainly will influence compliance of patients.Therefore, how on the basis that guarantees the Chinese prescription curative effect, cut down greatly in the prescription composition with improve compliance of patients, promote fast recovery of burn and healing, be the burn development trend of prescription of development and development of new Chinese medicine.
Summary of the invention
The objective of the invention is to overcome the problem of above existence, provide a kind of prescription more to simplify, the Chinese medicine composition that is used to promote fast recovery of burn of instant effect, easy to use, few side effects.
The present invention is achieved through following technical scheme:
Be used to promote the Chinese medicine composition of fast recovery of burn, adopt the component of following weight portion:
Gibberellins (920) 0.01-0.5 part, Mahonia fortunei (Lindl.) Fedde 50-150 part, Resina persicae 30-70 part, Rhizoma Polygoni Cuspidati 50-150 part, Borneolum Syntheticum 0.5-2 part, artificial Calculus Bovis 0.5-2 part, Oleum menthae 30-70 part.
Optimum weight part of each component is in the described Chinese medicine composition:
(920) 0.25 parts of gibberellins, 100 parts of Mahonia fortunei (Lindl.) Fedde, 50 parts of Resina persicaes, 100 parts of Rhizoma Polygoni Cuspidati, 1 part of Borneolum Syntheticum, 1 part of artificial Calculus Bovis, Peppermint Oil 50 part.
Oil preparation, ointment or the skin degerming water of said Chinese medicine composition for adopting traditional method to make.
Ancient Chinese medicine is thought burn for due to the fire-toxin, and burning hot impairment of YIN is accumulate malicious slough.Modern Chinese medicine propose burn be wound be again the neodoxy of skin ulcer, hinder then stagnation of QI and blood, the stasis of blood is then obstructed, the stagnation of QI is then wet long-pending, and is wet long-pending and poison is mould; Burn is due to the fire-toxin, and fire-toxin is skin ulcer then, and skin ulcer is in then pyretic toxicity is gone into, and skin ulcer is the slough pus and blood then, and the treatment burn should be treated with blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, putrefaction-removing granulation-promoting and control skin ulcer.Therefore, respond well with " heat-clearing and toxic substances removing, dampness detumescence, blood circulation promoting and blood stasis dispelling, putrefaction-removing granulation-promoting " treatment burn, can protect wound healing, reach the purpose of burn treating fast.
Each component complements each other in the Chinese medicine composition of the present invention, has the effect of heat-clearing and toxic substances removing, dampness detumescence, blood circulation promoting and blood stasis dispelling, putrefaction-removing granulation-promoting.Mahonia fortunei (Lindl.) Fedde in the Chinese medicine composition: nature and flavor are bitter flat, heat-clearing and toxic substances removing, the detumescence of regulating the flow of vital energy; Resina persicae: nature and flavor are bitter flat, promoting blood circulation and detumescence, treating stranguria pain relieving; Rhizoma Polygoni Cuspidati: nature and flavor are bitter flat, eliminating damp-heat, move back drench invigorate blood circulation, clots absorbing detoxifcation, putrefaction-removing granulation-promoting; Borneolum Syntheticum: nature and flavor are arduous, clearing heat for detumescence, antipruritic pain relieving; Artificial Calculus Bovis: nature and flavor bitter cold, heat-clearing and toxic substances removing, dispelling phlegm and relieving sore-throat; Herba Menthae: pungent in flavor and cool in property, wind-dispelling heat-dissipating is warded off dirty detoxifcation, is equipped with auxin in the Chinese medicine composition: gibberellins (920), it has the in-house nucleic acid of adjusting and protein, and then promotes the tissue function of growth fast.
The present invention at first filter out have eliminating damp-heat, the conventional Chinese medicine of blood circulation promoting competent silt burn composition Rhizoma Polygoni Cuspidati is on the effective ingredient basis; With seldom be used for before this burn treating two the flavor Chinese medicines: Mahonia fortunei (Lindl.) Fedde and Resina persicae join this Chinese medicine composition; The heat-clearing and toxic substances removing of Mahonia fortunei (Lindl.) Fedde, the detumescence of regulating the flow of vital energy, Resina persicae promoting blood circulation and detumescence, treating stranguria pain relieving and Rhizoma Polygoni Cuspidati eliminating damp-heat, blood circulation promoting competent silt three are combined; And be equipped with Borneolum Syntheticum, artificial Calculus Bovis and Herba Menthae; Make the Chinese medicine ingredients in the Chinese medicine composition be merely Six-element, in addition, the present invention is first with auxin: gibberellins (920) adds in the Chinese medicine composition; Utilize it to promote the skin histology function of growth fast, reach the purpose of the damaged wound surface of quickly-healing.Each component complements each other in the Chinese medicine composition of the present invention, can give play to the effect that quick treatment recovers burn.
In sum; The Chinese medicine composition advantage that the present invention filters out is: (1) is through strict theory demonstration and a large amount of experiment screenings, and is final on the basis of having selected Six-element Chinese medicine for use, added a kind of auxin originally: gibberellins (920); This compatibility has not only been simplified prescription; Control the quality problems in the production link effectively, in addition, the adding of gibberellins has promoted the quickly-healing and the recovery of skin histology in the burn wound more effectively; (2) have the advantages that preparation is convenient, with low cost, evident in efficacy, side effect is little; (3) can be made into various exterior-applied formulations, be very easy to patient's treatment needs.
Below in conjunction with embodiment the present invention is done further explanation.
The specific embodiment
The present invention is used to promote the Chinese medicine composition of fast recovery of burn, adopts following component and weight portion:
Embodiment 1
Gibberellins (920) 0.01g, Mahonia fortunei (Lindl.) Fedde 50g, Resina persicae 30g, Rhizoma Polygoni Cuspidati 150g, Borneolum Syntheticum 2g, artificial Calculus Bovis 2g, Oleum menthae 30 g.
Embodiment 2
Gibberellins (920) 0.05g, Mahonia fortunei (Lindl.) Fedde 80g, Resina persicae 40g, Rhizoma Polygoni Cuspidati 60g, Borneolum Syntheticum 1g, artificial Calculus Bovis 1g, Oleum menthae 40 g.
Embodiment 3
Gibberellins (920) 0.1g, Mahonia fortunei (Lindl.) Fedde 150g, Resina persicae 70g, Rhizoma Polygoni Cuspidati 1 30g, Borneolum Syntheticum 1.5g, artificial Calculus Bovis 0.5g, Peppermint Oil 70 g.
Embodiment 4
Gibberellins (920) 0.5g, Mahonia fortunei (Lindl.) Fedde 130g, Resina persicae 60g, Rhizoma Polygoni Cuspidati 50g, Borneolum Syntheticum 0.5g, artificial Calculus Bovis 0.7g, Oleum menthae 60 g.
Embodiment 5
Gibberellins (920) 0.25g, Mahonia fortunei (Lindl.) Fedde 100g, Resina persicae 50g, Rhizoma Polygoni Cuspidati 100g, Borneolum Syntheticum 1g, artificial Calculus Bovis 1g, Peppermint Oil 50 g.
Burn external-use oil preparation of the present invention, burn external ointment and external skin disinfectant can prepare on the basis of the foregoing description as follows:
1) Mahonia fortunei (Lindl.) Fedde of recipe quantity and Rhizoma Polygoni Cuspidati add 8-10 times of water gaging decoction 2 times earlier, each 1 hour, merge 2 times decoction liquor; When being concentrated into density and being 1.2g/ml (heat is surveyed), adds 3 times and measure volume of ethanol (95%), stir; Left standstill 48 hours; Get supernatant, reclaim ethanol, vacuum drying gets 2 kinds of medicinal substances extracts;
2) Resina persicae of recipe quantity is used an amount of dissolve with ethanol, the gibberellins, Borneolum Syntheticum, artificial Calculus Bovis and the Oleum menthae that add recipe quantity again fully stir;
3) with 1), 2) extract obtained and dissolve with ethanol mixture of step, add an amount of vegetable oil mixing and promptly get required burn oil preparation (processing 1000ml); Add an amount of oil-in-water type emulsifiable paste matrix mixing and promptly get required Sunice agent (processing 1000g); Add 30% an amount of ethanol mixing and promptly get required skin degerming water (processing 1000ml).
The administrated method of burn external-use oil preparation, burn external ointment and external skin disinfectant:
Burn external-use oil preparation, burn external ointment method for using are: spread upon local skin, look the burn degree, do not wait for 3-10 time every day; Skin degerming moisture is loaded in the aerosol type container, is sprayed on required skin surface, looks the burn degree, does not wait for 3-10 time every day.
The effect of Chinese medicine composition of the present invention can be explained through following pharmacodynamics data.
1, zoopery
The Chinese medicine composition that adopts the foregoing description is as the invention drug group, and other adopts a kind of Chinese prescription that promotes fast recovery of burn as the Chinese medicine matched group, and it is formed by removing gibberellins (920) in the above-mentioned Chinese medicine composition.
This experimental example is specifically through two drug group: invention drug group and the pharmacodynamics evaluation to burn wound healing in zoopery of Chinese medicine matched group embody.
Laboratory animal is divided into groups and the model preparation: 40 of cleaning level SD rats, body weight 230～250g, male and female half and half.Lumbar injection water and the anesthesia of chloral liquid, the back depilation.Anaesthetize with method next day, uses the constant temperature and pressure scald apparatus, and with diameter 2.5 cm, 90 ℃, 2.3 kPa pressure scald rat back skin 15s, processes 3 of the dark II degree wound surface (confirming through pathology) of diameter 2.5cm, and each wound surface is 1cm at interval.Middle wound surface is the burn matched group; Other two wound surface are respectively invention medication therapy groups and Chinese medicine contrast treatment group.Exposure method, wound surface is changed dressings 1 time every day.
The drawing materials and handling of BIAO and BEN: hinder back 5,10,15,20,25d each the time put mutually and put to death 8, get the wound surface BIAO and BEN, detect the hydroxyproline content and the I/III Collagen Type VI ratio of wound surface respectively.Hydroxyproline content and I/III Collagen Type VI ratio BIAO and BEN is put in the cryovial-80 ℃ of preservations.
Whether observation index is the wound surface gross examination of skeletal muscle 1.: the perusal edema wound oozed out degree when changed dressings every day, dry, and all rednesses of noinvasive and secretions etc. are arranged.2. observe wound healing time: turn to the healing standard with the complete epithelium of wound surface, and confirm through wound surface pathological section HE dyeing.3. measure and hinder back 5,10,15,20, the wound surface hydroxyproline content of 25d (sample alkali hydrolysis method); I/III Collagen Type VI ratio (ELISA method).
Result: 1, wound surface gross examination of skeletal muscle: it is white to hinder back 1～3 d burn matched group wound surface skin-color, and swelling has and oozes out and create the week redness.It is red and swollen that face noinvasive week is formed in invention medication therapy groups and Chinese medicine contrast treatment.It is dry to hinder back 2d invention medication therapy groups wound surface, and all the other 2 are formed face and be dried to crust to hinder back 3 d.Invention medication therapy groups and Chinese medicine contrast treatment group do not have secretions under the crust in agglutination, the burn matched group secretions occurring under 14d part wound surface (2/5) crust after the wound.2, the wound surface The average healing is: burn matched group 23.8 d; Chinese medicine contrast treatment group 18.4d; Burn line of oils 14. 2d.3, wound surface is hindered back different time hydroxyproline content: the hydroxyproline content that face is formed in invention medication therapy groups and Chinese medicine contrast treatment all is higher than the burn matched group; The a little higher than Chinese medicine contrast of the hydroxyproline content treatment group of invention medication therapy groups wound surface; Invention medication therapy groups 9d after wound reaches the peak; Chinese medicine contrast treatment group 13d after wound reaches the peak, and concrete outcome is seen table 1.4, wound surface is hindered back different time I/III Collagen Type VI ratio: the I/III Collagen Type VI ratio of invention medication therapy groups and Chinese medicine contrast treatment group all is lower than the burn matched group; I/III Collagen Type VI the ratio of invention medication therapy groups is lower than Chinese medicine contrast treatment group slightly, and concrete outcome is seen table 1.
Table 1 wound surface different time hydroxyproline content and I/III Collagen Type VI ratio
2, antibacterial experiment:
Preparation contains staphylococcus aureus, bacillus pyocyaneus, colibacillary bacterial suspension respectively, and getting 18 hours 24 hours bacterial clumps of general common cultivation and normal saline, to be made into bacterial content with normal concentration pipe colorimetric behind the mixing in vitro be 4 * 10
8The bacterial suspension of individual/milliliter.
Tube dilution method: Strict aseptic operation; Get three groups of sterilization test tubes (representing a bacterial strain for every group); Every component three rows (representing burn medicine oil agent group, burn medicine emulsifiable paste group, moistening burning disinfectant group respectively); Each arranges 13, and every row gets 3 same test tubes in addition, respectively labelling " negative tube " (adding meat soup 2mL), " sample cell " (adding people's meat soup 2mL, sample 2mL), " positive pipe " (adding three kinds of each 2mL of bacterium liquid, meat soup 2mL, sample 2mL respectively).L number-No. 2 test tubes of every group of every row add each 2mL of medicine stock solution, add nutrient broth 2mL from No. 2-No. 13 every test tubes, and sucking-off 2rnL is added in No. 3 pipes behind No. 2 pipe mixings, two-fold dilution's to No. 13 pipe successively, and sucking-off 2mL discards.Each pipe adds 10
-7Bacteria suspension 0.1mL.Each pipe is observed to 35 ℃ of cultivation 24h.
Criterion: if test tube liquid is muddy and/or deposition, special color are arranged for bacterial growth is arranged, if test tube liquid clear is not seen muddiness, deposition or special color, for bacterial growth is not arranged.The least concentration of not growing with antibacterial is the minimum inhibitory concentration (MIC) of experiment medicine to this bacterium.Do not see after bacterial growth is respectively managed the mixing of culture whirlpool and draw 2 plates of 0.1mL injection respectively.Ensure Liquid agar culture medium 15mL.Observe after cultivating 37 ℃ of 24 h.Criterion: with bacterium colony on the viable bacteria counting method inspection plate.Average is minimum bactericidal concentration (MBC) less than 5 minimum dilution drug level.
The result shows: compare between minimum inhibitory concentration; The Sunice agent is minimum to staphylococcus aureus, colibacillary MIC; The burn oil preparation is minimum to the MIC value of bacillus pyocyaneus, and is suitable to the MIC value of staphylococcus aureus burned skin disinfectant, two kinds of medicines of burn oil preparation; Minimum bactericidal concentration (MBC) relatively; Burned skin disinfectant group and Sunice agent group are suitable to staphylococcus aureus MBC value; The burn oil preparation is minimum to bacillus pyocyaneus MBC value, and the burned skin disinfectant is to escherichia coli MBC value minimum (concrete outcome is seen table 2).
The standards of grading of table 2 skin irritation reaction
3, irritant experiment:
24 of rabbit, male and female half and half, raise a week after; Be divided into three groups greatly at random, be respectively burn oil preparation group, Sunice group and burned skin disinfectant group, divide two groups again under each big group; One group was intact skin administration group, and one group is damaged skin administration group, in preceding 24 hours of experiment; Rabbit is lost hair or feathers the about 6.0cm * 6.0cm of every side depilation area along back ventralward.The damaged tame rabbit back depilation district that organizes treats that with No. zero Sandpapering skin rubescent stopping the standard of point-like oozing of blood as damaged skin to occur with skin for a moment; Rabbit depilation district after 24 hours that skin is qualified coats Chinese medicine composition of the present invention respectively: burn oil preparation, ointment and skin degerming water; The coating area is 4.0cm * 4.0cm, fixes with nonirritant adhesive plaster and binder then, and the coating time is 6 hours; After coating finishes; Remove and tried drug combination warm water cleaning medicine-feeding part, administration every day 1 time, continuous 7 days; Observe the local application position after administration every day and have or not situation such as erythema and edema, 6h, 24h, 48h and 72h local skin change after the administration of primary part observation last.
Estimate by table 3 standards of grading.IR score value addition with every group of rabbit is the last total mark that this receives reagent thing irritative response; Total mark is the last score value of this treated animal skin irritation divided by number of animals, estimates irritating intensity by the standards of grading of table 4.In addition, last is observed the back and is put to death rabbit, clip administration place skin, perusal has or not erythema, edema, and with 10% both formalin fixing after, paraffin section, dyeing, microscopically observation skin has or not situation such as inflammatory cell infiltration, hemorrhage, necrosis.
The standards of grading of table 3 skin irritation reaction
Table 4 skin irritation intensity evaluation standard
After 6 hours and last administration after each administration, the irritative response situation of rabbit administration place skin checked in 6,24,48 and 72 hours, mark, calculate meansigma methods, and compare with intact skin administration group by standards of grading.The result: three kinds of external-use burn preparations are zero to the comprehensive grading of rabbit, and show Chinese medicine composition of the present invention three kinds: oil preparation, ointment and skin degerming water multiple dosing are to rabbit complete sum damaged skin nonirritant.
In addition, microscopically observe to show that burn respectively each rabbit epidermis after oil preparation group, Sunice agent group and the burned skin disinfectant group, intradermal of intact skin all do not see hyperemia, hemorrhage, necrosis and inflammatory cell.Damaged skin give to burn respectively each rabbit epidermis after oil preparation group, Sunice agent group and the burned skin disinfectant group, intradermal all do not seen hyperemia, hemorrhage, necrosis and inflammatory cell.
4, clinical experiment
Each the clinical therapeutic efficacy report after 60 examples amount to the 180 routine patients of burn wound uses of burn external-use oil preparation of the present invention, burn external ointment and external skin disinfectant: in the 180 routine cases, male 125 examples, women 55 examples, the oldest 68 years old, minimum 2 years old.According to the chapter 13 first segment of the 6th edition " surgery " teaching material in People's Health Publisher, burn surface area and degree of depth criteria classification in clinical manifestation and the diagnosis, with the burn degree be divided into gently, in, 3 types of severes.Wherein in the 180 routine cases, minor burn 107 examples, moderate burn 67 examples, severe burn 6 examples.
Curative effect judging standard is: recovery from illness: wound surface heals fully, and slight 6 days, moderate 16 days, severe 32 days, burn wound healing person in the regulation healing time.Effectively: burn wound dwindles in the regulation healing time, but healing person fully not.Invalid: the burn wound that exceeds schedule time does not have any variation.
The result is as shown in table 5: traditional Chinese medicine composition for treating cure rate of the present invention is 85.56%, and effective percentage is 11.11%, and inefficiency is: 3.33%.
Table 5 180 examples a burn case and treat the curative effect statistical table
Claims (3)
1. Chinese medicine composition that is used to promote burn rehabilitation is characterized in that adopting following bulk drugs component:
Gibberellins 0.01-0.5 part, Mahonia fortunei (Lindl.) Fedde 50-150 part, Resina persicae 30-70 part, Rhizoma Polygoni Cuspidati 50-150 part, Borneolum Syntheticum 0.5-2 part, artificial Calculus Bovis 0.5-2 part, Oleum menthae 30-70 part.
2. the Chinese medicine composition that is used to promote burn rehabilitation according to claim 1 is characterized in that crude drug component and the weight portion thereof in the described Chinese medicine composition is:
0.25 part of gibberellins, 100 parts of Mahonia fortunei (Lindl.) Fedde, 50 parts of Resina persicaes, 100 parts of Rhizoma Polygoni Cuspidati, 1 part of Borneolum Syntheticum, 1 part of artificial Calculus Bovis, Peppermint Oil 50 part.
3. the Chinese medicine composition that is used to promote burn rehabilitation according to claim 1 and 2 is characterized in that oil preparation, ointment or the skin degerming water of said Chinese medicine composition for adopting traditional method to make.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1156620A (en) * | 1996-12-09 | 1997-08-13 | 李铭 | Chinese herbal medicine for treating burn, and skin and external diseases and preparing process thereof |
| CN1211445A (en) * | 1998-09-16 | 1999-03-24 | 姜长鸿 | Paste for burn and scald |
| CN1559460A (en) * | 2004-03-11 | 2005-01-05 | 王小鹏 | Wet and thermophily Chinese herb medicinal liquid for treating burn and scald, and its prepn. method |
| CN1935159A (en) * | 2006-09-18 | 2007-03-28 | 吴方忠 | Chinese medicine composition for treating burn, empyrosis and bodysurface ulcer and its preparing method |
| CN101091779A (en) * | 2007-07-05 | 2007-12-26 | 周高箭 | Powder of bluestone for burn |
-
2010
- 2010-08-19 CN CN2010102571220A patent/CN101904915B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1156620A (en) * | 1996-12-09 | 1997-08-13 | 李铭 | Chinese herbal medicine for treating burn, and skin and external diseases and preparing process thereof |
| CN1211445A (en) * | 1998-09-16 | 1999-03-24 | 姜长鸿 | Paste for burn and scald |
| CN1559460A (en) * | 2004-03-11 | 2005-01-05 | 王小鹏 | Wet and thermophily Chinese herb medicinal liquid for treating burn and scald, and its prepn. method |
| CN1935159A (en) * | 2006-09-18 | 2007-03-28 | 吴方忠 | Chinese medicine composition for treating burn, empyrosis and bodysurface ulcer and its preparing method |
| CN101091779A (en) * | 2007-07-05 | 2007-12-26 | 周高箭 | Powder of bluestone for burn |
Non-Patent Citations (2)
| Title |
|---|
| 冯国旗等.虎杖治疗烧伤创面的临床应用.《河南中医药学刊》.1996,(第05期),39-40. * |
| 刘丹等.虎杖复方制剂的研究及其临床应用概况.《药学实践杂志》.2007,(第02期),68-72. * |
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