CN101904804A - Skin whitening complex prepared from algae serving as main raw materials - Google Patents

Skin whitening complex prepared from algae serving as main raw materials Download PDF

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Publication number
CN101904804A
CN101904804A CN2010101951059A CN201010195105A CN101904804A CN 101904804 A CN101904804 A CN 101904804A CN 2010101951059 A CN2010101951059 A CN 2010101951059A CN 201010195105 A CN201010195105 A CN 201010195105A CN 101904804 A CN101904804 A CN 101904804A
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CN
China
Prior art keywords
algae
exo
whitonyl
sample
raw materials
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Pending
Application number
CN2010101951059A
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Chinese (zh)
Inventor
蒋丽刚
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proya Huzhou Cosmetics Co Ltd
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Proya Huzhou Cosmetics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Proya Huzhou Cosmetics Co Ltd filed Critical Proya Huzhou Cosmetics Co Ltd
Priority to CN2010101951059A priority Critical patent/CN101904804A/en
Publication of CN101904804A publication Critical patent/CN101904804A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a skin whitening complex prepared from algae serving as main raw materials, which comprises Whitonyl and EXO-T in a weight part ratio of 3:5-7:1. After the optimal proportion range, the produced cosmetics are added with 0 to 5 percent of the mixed complex at room temperature, and is stirred uniformly and bottled. Experimental results show that: on the premise of controlling 4 percent of total active substances, when the complexing ratio of the Whitonyl to the EXO-T exceeds 3:5, the monophenyl oxidase inhibiting capacity is higher than any single substance therein; when the complexing ratio of the Whitonyl to the EXO-T is 3:5, the monophenyl oxidase inhibiting capacity is the highest; and when the complexing ratio of the Whitonyl to the EXO-T exceeds 3:1, the monophenyl oxidase inhibiting capacity begins reducing.

Description

A kind of is the skin-whitening compound of primary raw material with the algae
Technical field
The present invention relates to cosmetics, relating in particular to the algae is the skin-whitening compound of primary raw material.
Background technology
Cosmetics industry is constantly sought technological break-through for many years, and purpose is to release the class raw material of whitening of highly effective and safe.The predominating path that dermal melanin forms is that the tryrosinase in the skin is converted into DOPA with tyrosine, further transforms into the DOPA quinone, forms melanin at last.Common skin-whitening method all is the activity by restraint of tyrosinase, thereby reaches the effect of skin whitening.
Use the whitening composition of more synthetic to have at present, vitamin C and derivant thereof, arbutin, kojic acid etc., but their common shortcomings are its unstable properties, oxidized easily, can flavescence gradually in storage process, thus cause product in storage process, to extend gradually xanthochromia and lose commercial value.For the other plant extract, such as glabridin, mulberry root extract, lemon yellow melon extract, but this class material whitening function a little less than, being difficult to proves its actual effect of whitening with experimental data.
Bibliographical information seldom be the material of whitening from the ocean, consider that marine resources are very abundant, raw material sources are abundant, if can therefrom seek the material of really effectively whitening, then are a very significant job.Read up the literature and can learn, existing abroad this respect is attempted, and as a Japanese ball company three kinds of specific marine algae productions of selection extract of whitening is arranged, and is used for cosmetics industry; Also there is the extract that comes from Atlantic Ocean red algae in the rich company of France's hila, and the class cosmetics are used to whiten.In addition, seldom other documents are mentioned the progress of this respect.
Summary of the invention
By the tyrosinase inhibition rate test experiments, after the composite application of raw material of proof with two kinds of different purposes that come from marine algae, experimental results show that it can be than the activity of only using the more effective restraint of tyrosinase of wherein a kind of energy, and then can infer that this material uses wherein a kind of to have more white-skinned face function (tyrosinase inhibition rate test be standard be used to test the method for testing of active substance whitening function of whitening) than simple.
White clever Whitonyl of algae and Ai Ke head are used in cosmetics for two kinds of raw materials of EXO-T are composite, and after determining its best ratio range, in the cosmetics of making, add 0~5% above-mentioned mixing compound under room temperature, the back bottling that stirs gets final product.
Selection sends the first EXO-T of replacing of love section of UNIPEX company to make up from the white clever Whitonyl of algae of the rich SILAB company of French hila with from the excellent Buddhist nun of Canada, wherein the white preferred proportion clever and that the head of love section replaces of algae is 3: 5~7: 1, the whiten weight range that contains of raw material of this mixing is 0~5% in final products, the white spirit of algae of the rich company of wherein French hila is the oligosaccharide that comes from Palmaria palmate red algae, this raw material can limit melanic generation, effectively stop the operation of melanosome and the calmness of control photoinduction pigment, thereby senile plaque and brown macules desalination that illumination is caused are the class materials of whitening that a usefulness has obtained confirming; The love section of Canada UNIPEX company is first to be the vibrio alginolyticus extracellular polysaccharide Vibrio Exopolysaccharide that comes from French Polynesia corallineae surface attachment for EXO-T, this raw material can impel skin cell differentiation, horny layer breaks away from, and itself there is no the white-skinned face function of real meaning.
The concrete grammar of tyrosinase inhibition rate test is:
1. the potassium phosphate solution that adds the 0.1M of 500 μ l in the tyrosine solution of 0.3mg/ml adds the tester of 450 μ l, mix homogeneously in test tube, and constant temperature is at 37 degree;
2. add 50 μ l tryrosinase solution (concentration is 1250unit/ml), under 37 degree environment, cultivated 10 minutes;
3. test the absorbance of 480nm with the UV-VIS spectrophotometer.
The composition of tester is according to hereinafter described:
Add the raw material of following content in deionized water respectively, its meansigma methods and standard deviation are measured in every kind of sample test 3 times.
Sample 1 4% algae is spirit in vain
Sample 2 4% head of love section replace
Sample 3 0.5% algaes are spirit in vain, and 3.5% head of love section replaces
Sample 4 1% algaes are spirit in vain, and 3% head of love section replaces
Sample 5 1.5% algaes are spirit in vain, and 2.5% head of love section replaces
Sample 6 2% algaes are spirit in vain, and 2% head of love section replaces
Sample 7 3% algaes are spirit in vain, and 1% head of love section replaces
Sample 8 3.25% algaes are spirit in vain, and 0.75% head of love section replaces
Sample 9 3.5% algaes are spirit in vain, and 0.5% head of love section replaces
Sample 10 blank deionized waters
The result of the test that this product experienced is as follows:
Tryrosinase suppresses data
Sample number 480nm absorbance meansigma methods standard deviation suppresses %
Sample 10 0.4715 0.4633 0.4826 0.472 0.009686-
Sample 1 0.6026 0.5973 0.5422 0.581 0.033447 33.1
Sample 2 0.7933 0.7249 0.7999 0.773 0.041527 11.0
Sample 3 0.7213 0.6785 0.6967 0.699 0.02148 19.5
Sample 4 0.3492 0.3527 0.3653 0.356 0.008468 24.6
Sample 5 0.5512 0.5437 0.5268 0.541 0.012498 34.6
Sample 6 0.2692 0.2764 0.2685 0.271 0.004373 42.5
Sample 7 0.3778 0.3563 0.3423 0.359 0.017882 58.7
Sample 8 0.1855 0.1785 0.1816 0.182 0.003508 57.9
Sample 9 0.4123 0.4298 0.4256 0.423 0.009136 48.8
The above results shows: is controlled at active substance under the prerequisite of 4% total amount,
1. when the white spirit of algae with love section is first when surpassing 3: 5 for compound proportion, its tryrosinase inhibition ability has been better than any independent use a kind of material wherein;
2. replace compound proportion in 3: 1 in white spirit of algae and the head of love section, it is the strongest that its tryrosinase suppresses ability;
When the white spirit of algae and love section is first surpass 3: 1 for compound proportion after, its tryrosinase inhibition ability begins decline.

Claims (1)

1. one kind is the skin-whitening compound of primary raw material with the algae, it is characterized in that it comprises that white spirit of algae and the head of love section replace, and the ratio of weight and number that white spirit of described algae and the head of love section replace was respectively 3: 5~7: 1.
CN2010101951059A 2010-06-09 2010-06-09 Skin whitening complex prepared from algae serving as main raw materials Pending CN101904804A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010101951059A CN101904804A (en) 2010-06-09 2010-06-09 Skin whitening complex prepared from algae serving as main raw materials

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2010101951059A CN101904804A (en) 2010-06-09 2010-06-09 Skin whitening complex prepared from algae serving as main raw materials

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CN101904804A true CN101904804A (en) 2010-12-08

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150352036A1 (en) * 2011-12-19 2015-12-10 Mary Kay Inc. Combination of plant extracts to improve skin tone
US10500152B2 (en) 2014-03-10 2019-12-10 Mary Kay Inc. Skin lightening compositions
US10682381B2 (en) 2009-04-27 2020-06-16 Mary Kay Inc. Botanical formulations
US11040058B2 (en) * 2008-04-15 2021-06-22 Lucas Meyer Cosmetics Canada Inc. Cosmetic compositions comprising exopolysaccharides derived from microbial mats, and methods of use thereof
US11793705B2 (en) 2021-08-13 2023-10-24 Zhejiang Yihengyue Medical Technology Co., Ltd. Fall-resistant method of intelligent rollator, intelligent rollator and controller thereof

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11040058B2 (en) * 2008-04-15 2021-06-22 Lucas Meyer Cosmetics Canada Inc. Cosmetic compositions comprising exopolysaccharides derived from microbial mats, and methods of use thereof
US11752168B2 (en) 2008-04-15 2023-09-12 Lucas Meyer Cosmetics Canada Inc. Methods of using cosmetic compositions comprising exopolysaccharides derived from microbial mats
US10682381B2 (en) 2009-04-27 2020-06-16 Mary Kay Inc. Botanical formulations
US10953058B2 (en) 2009-04-27 2021-03-23 Mary Kay Inc. Botanical formulations
US11638735B2 (en) 2009-04-27 2023-05-02 Mary Kay Inc. Botanical formulations
US20150352036A1 (en) * 2011-12-19 2015-12-10 Mary Kay Inc. Combination of plant extracts to improve skin tone
US9861573B2 (en) * 2011-12-19 2018-01-09 Mary Kay Inc. Combination of plant extracts to improve skin tone
US10780041B2 (en) 2011-12-19 2020-09-22 Mary Kay Inc. Combination of plant extracts to improve skin tone
US11865202B2 (en) 2011-12-19 2024-01-09 Mary Kay Inc. Combination of plant extracts to improve skin tone
US10500152B2 (en) 2014-03-10 2019-12-10 Mary Kay Inc. Skin lightening compositions
US11793705B2 (en) 2021-08-13 2023-10-24 Zhejiang Yihengyue Medical Technology Co., Ltd. Fall-resistant method of intelligent rollator, intelligent rollator and controller thereof

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Application publication date: 20101208