CN101890058A - Health-care bio-chip based on nano-taxus and preparation method thereof - Google Patents
Health-care bio-chip based on nano-taxus and preparation method thereof Download PDFInfo
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- CN101890058A CN101890058A CN2009100593129A CN200910059312A CN101890058A CN 101890058 A CN101890058 A CN 101890058A CN 2009100593129 A CN2009100593129 A CN 2009100593129A CN 200910059312 A CN200910059312 A CN 200910059312A CN 101890058 A CN101890058 A CN 101890058A
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Abstract
The invention provides a health-care bio-chip based on nano-taxus and a preparation method thereof. In the invention, the nano-taxus which is taken as the raw material and has the average particle size of 1nm to 1,000nm is attached to or loaded into a carrier with good permeability and high absorption capacity to obtain soft chips. The health-care bio-chip prepared by the invention can be conveniently and directly stuck to human skin and also can be arranged in the interlayer of underclothes or stuck to the inner layer of the underclothes, so that the bio-chip has comfortableness and concealment performance. By making full use of super-high permeability, i.e., the high capability of the nano-taxus to carry out transdermal absorption, the nano-taxus on the health-care bio-chip can improve the local microcirculation, reduce the incidence of various cancers and achieve good auxiliary curative effects on various common diseases in the convenient and comfortable administration process by allowing the nano-taxus to contact the human skin via carrier materials and ordinary thin-layer textile fabrics.
Description
Technical field
The present invention relates to a kind of health-care bio-chip based on nano-taxus and preparation method thereof, more particularly, relating to a kind of is convenience health-care bio-chip used in everyday of making of raw material and preparation method thereof with the nanometer taxus chinensis powder.
Background technology
Ramulus et folium taxi cuspidatae (basic taxaceae evergreen shrubs or arbor) is universally acknowledged endangered natural rare plants for anticancer, because of containing anticancer specific medicament---and paclitaxel is very precious.Paclitaxel all has significant curative effect to advanced breast cancer, ovarian cancer, uterus carcinoma, esophageal carcinoma, nasopharyngeal carcinoma, upper gastrointestinal cancer, bladder cancer, lymphatic cancer, carcinoma of prostate, malignant melanoma, tumor of head and neck, cellule type and lung cancer in non-cellule type, is described as " last line of defense of patient with advanced cancer ".Food and drug administration (FDA) goes on the market as the medicine for the treatment of diseases such as advanced ovarian cancer, uterus carcinoma, pulmonary carcinoma at official approval paclitaxel in 1992.Ramulus et folium taxi cuspidatae contains the active element of 100 multiple beneficial healths, except paclitaxel, also contain the several amino acids and the trace element of taxine, diterpenoids chemical compound and needed by human in the Ramulus et folium taxi cuspidatae, remarkable efficacy is all arranged for hypertension, hyperlipidemia, hyperglycemia, diabetes, rheumatoid, dysuria, menoxenia, postnatal blood stasis, adnexitis, uterine adenomyosis, dysmenorrhea, gonorrhea, nephritis, gastritis, enteritis, hemorrhoid etc.Because Ramulus et folium taxi cuspidatae is China first class of protection plant, also be that endangered plants are treasured in the world, wild Ramulus et folium taxi cuspidatae quantity is few and forbid felling, and resource is very valuable.The Ramulus et folium taxi cuspidatae of artificial growth comes to the ripening period now, can rationally pluck to be used for production and processing, contributes for human health effectively.
Ramulus et folium taxi cuspidatae is mainly used in the extraction paclitaxel at present, other contained in the Ramulus et folium taxi cuspidatae a large amount of beneficiating ingredients in leaching process, have been wasted, cause the significant wastage of taxus resource and paclitaxel price extremely expensively, numerous economic capabilities limited cancer patient can't buy.In fact, paclitaxel is for the cancer patient who has made a definite diagnosis provides treatment, and more sub-health population does not need paclitaxel, helps prevent cell carcinogenesis, reduces the health product of suffering from the cancer probability, having various health care functions concurrently but need.Have some health products of making as raw material with Ramulus et folium taxi cuspidatae on the market now, as health taxad tea, health-care cup, health promoting decoction etc., mostly be to adopt Ramulus et folium taxi cuspidatae is simply pulverized the back by boiling the mode of drinking in the hope of realizing certain anticancer health-care effect, but produce little effect because of paclitaxel is insoluble in water.Also there be not at present a kind of various anticancer functions and health-care effect and the daily comfortable health product easy to use that can give full play to Ramulus et folium taxi cuspidatae, and the present invention adopts the principle of pasting type therapy, make full use of the drug effect of Ramulus et folium taxi cuspidatae by Transdermal absorption, using method is simple, just in time can fill up this blank.
Summary of the invention
The purpose of this invention is to provide a kind of health-care bio-chip based on nano-taxus and preparation method thereof.
The present invention with mean diameter be the nanometer taxus chinensis powder of 1～1000 nanometer as raw material, it attached on the strong carrier of good permeability, absorption affinity or in the carrier of packing into, is made softish thin slice, and can make different shapes and pattern as required.During use, the extremely strong nanometer taxus chinensis powder of penetration can play a role constantly by Transdermal absorption on the health-care bio-chip based on nano-taxus, use by different body parts, can improve the local microcirculation of corresponding site, reduce breast carcinoma, ovarian cancer, uterus carcinoma, esophageal carcinoma, nasopharyngeal carcinoma, the upper gastrointestinal cancer, bladder cancer, lymphatic cancer, carcinoma of prostate, malignant melanoma, tumor of head and neck, the sickness rate of cellule type and lung cancer in non-cellule type etc. is for hypertension, hyperlipidemia, hyperglycemia, diabetes, rheumatoid; dysuria; menoxenia; postnatal blood stasis; adnexitis; uterine adenomyosis; dysmenorrhea; gonorrhea; nephritis; gastritis; enteritis; hemorrhoid etc. also have good auxiliary curative effect.Described health-care bio-chip based on nano-taxus comprises straight subsides formula chip series, embedded chip series, back glue type chip series.
Described straight subsides formula chip is that nanometer taxus chinensis powder and about 80 degrees centigrade ester acrylate pressure-sensitive glue for medical use are mediated evenly, and the ratio of nanometer taxus chinensis powder is about 10-60%, and colloid mixture is coated on the non-woven fabrics base material, covers release paper and make on colloid.Remove release paper during use, be affixed on the skin of desired area and get final product.
Described embedded chip is to be that PE membrane material, another side are in the slim medicated bag of non-woven fabrics material and make with the nanometer taxus chinensis powder one side of packing into.During use chip is inserted the interlayer of underclothes, the one side of non-woven fabrics material is got final product towards body skin.
Described back glue type chip is to be made into tripartite sealed bag with PE film base material and non-woven fabrics lining, at PE film back side coating medical pressure sensitive adhesive and cover release paper, packs nanometer taxus chinensis powder into then in bag and makes.Remove release paper during use, keep flexible contacting to get final product the skin that is attached to the nexine inboard of underclothes with the colloidal back side, makes the chip front side that contains nanometer taxus chinensis powder and corresponding site.
Compare with existing product, the present invention has following tangible advantage: 1, the medical value of Ramulus et folium taxi cuspidatae is high, and the penetration of nanometer taxus chinensis powder is extremely strong, and by just making the drug effect infiltration with contact skin, user not only saves time but also save worry; 2, ester acrylate pressure-sensitive glue for medical use stability of the present invention is high, release property is good, harmless, not irritated during use, the moisture that can keep local skin, continuously reach five days service time (artificial peel off except), fine but the sticking chaeta of its viscosity, do not have pain perception when tearing, use as snug as a bug in a rug; 3, the health-care bio-chip based on nano-taxus volume is small and exquisite frivolous, does not have abnormal sensory when cooperating underclothes to use, and also can not influence the attractive in appearance of medicated clothing, has good comfortableness and disguise; 4, health-care bio-chip based on nano-taxus can be made different shapes and pattern as required, both convenient cooperation medicated clothing uses, be attached to become again on the skin and dazzle beautiful ornament, change the dull profile that tradition sticks articles for use, make it have the double effects of health product and fashion decorations concurrently; 5, material of the present invention all has good stable, and is easy to use, stores easy; 6, the Ramulus et folium taxi cuspidatae that the present invention utilized comprises its root, stem, leaf, does and bark, and promptly the Ramulus et folium taxi cuspidatae Herb all can utilize, and has both made full use of the beneficiating ingredient at each position of Ramulus et folium taxi cuspidatae, can reduce cost again, reduces the price of goods, and is economical and practical, benefits the people.
The specific embodiment
Below by the specific embodiment the present invention is described in further detail:
Straight subsides formula chip of the present invention is that nanometer taxus chinensis powder and about 80 degrees centigrade ester acrylate pressure-sensitive glue for medical use are mediated evenly, and the ratio of nanometer taxus chinensis powder is about 10-60%, can come resize ratio according to different needs.To mediate colloid by coating equipment and be coated on the non-woven fabrics base material, on colloid, cover release paper immediately, be molded as the shape that needs, promptly can be made into straight subsides formula chip of the present invention by cutting.During use release paper is removed, be affixed on the skin of desired area and get final product.
Embedded chip of the present invention is to pack into nanometer taxus chinensis powder simultaneously to be that PE membrane material, another side are in the slim medicated bag of non-woven fabrics material, promptly to can be made into embedded chip of the present invention.During use chip is inserted the interlayer of underclothes, the one side of non-woven fabrics material is got final product towards body skin.
Back glue type chip of the present invention is to be made into tripartite sealed bag with PE film base material and non-woven fabrics lining, and at PE film back side coating medical pressure sensitive adhesive and cover release paper, the nanometer taxus chinensis powder of packing in bag then promptly can be made into back glue type chip of the present invention.Remove release paper during use, keep flexible contacting to get final product the skin that is attached to the nexine inboard of underclothes with the colloidal back side, makes the chip front side that contains nanometer taxus chinensis powder and corresponding site.
Claims (7)
1. health-care bio-chip, it is characterized in that be with mean diameter be the nanometer taxus chinensis powder of 1～1000 nanometer as the made flexible sheets of raw material, can make different shapes and pattern as required.
2. make the method for the described health-care bio-chip of claim 1, it is characterized in that being is that the nanometer taxus chinensis powder of 1～1000 nanometer is as raw material with mean diameter, it attached on the strong carrier of good permeability, absorption affinity or in the carrier of packing into, is made softish thin slice.
3. according to claim 1,2 described health-care bio-chips, it is characterized in that comprising straight subsides formula chip series, embedded chip series, back glue type chip series.
4. straight subsides formula chip according to claim 3, it is characterized in that it being that nanometer taxus chinensis powder and about 80 degrees centigrade ester acrylate pressure-sensitive glue for medical use are mediated evenly, the ratio of nanometer taxus chinensis powder is about 10-60%, can come resize ratio according to different needs, to mediate colloid by coating equipment is coated on the non-woven fabrics base material, on colloid, cover release paper immediately, be molded as the shape that needs by cutting.
5. embedded chip according to claim 3 is characterized in that it being that packing into nanometer taxus chinensis powder simultaneously is that PE membrane material, another side are in the slim medicated bag of non-woven fabrics material, so that insert the interlayer of underclothes.
6. back glue type chip according to claim 3 is characterized in that it being to be made into tripartite sealed bag with PE film base material and non-woven fabrics lining, at PE film back side coating medical pressure sensitive adhesive and cover release paper, the nanometer taxus chinensis powder of packing into then in bag.Can be attached to the nexine inboard of underclothes with the colloidal back side.
7. according to claim 1,2,4,5,6 described Ramulus et folium taxi cuspidatae, refer to root, stem, leaf, the dried and bark of basic taxaceae evergreen shrubs or arbor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100593129A CN101890058A (en) | 2009-05-18 | 2009-05-18 | Health-care bio-chip based on nano-taxus and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009100593129A CN101890058A (en) | 2009-05-18 | 2009-05-18 | Health-care bio-chip based on nano-taxus and preparation method thereof |
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| CN101890058A true CN101890058A (en) | 2010-11-24 |
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| CN2009100593129A Pending CN101890058A (en) | 2009-05-18 | 2009-05-18 | Health-care bio-chip based on nano-taxus and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247304A (en) * | 2010-05-18 | 2011-11-23 | 粟时献 | Health care cosmetics in nano Chinese yew series and production method thereof |
| CN102406245A (en) * | 2011-11-07 | 2012-04-11 | 胡红节 | Taxus chinensis-containing bra |
-
2009
- 2009-05-18 CN CN2009100593129A patent/CN101890058A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247304A (en) * | 2010-05-18 | 2011-11-23 | 粟时献 | Health care cosmetics in nano Chinese yew series and production method thereof |
| CN102406245A (en) * | 2011-11-07 | 2012-04-11 | 胡红节 | Taxus chinensis-containing bra |
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Open date: 20101124 |