CN101862441A - Liniment containing natural Zingiber corallinum Hance essential oil with functions of analgesia, antiphlogosis, detumescence and itching-relieving - Google Patents
Liniment containing natural Zingiber corallinum Hance essential oil with functions of analgesia, antiphlogosis, detumescence and itching-relieving Download PDFInfo
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- CN101862441A CN101862441A CN201010103508A CN201010103508A CN101862441A CN 101862441 A CN101862441 A CN 101862441A CN 201010103508 A CN201010103508 A CN 201010103508A CN 201010103508 A CN201010103508 A CN 201010103508A CN 101862441 A CN101862441 A CN 101862441A
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Abstract
The invention provides an external liniment which has the functions of analgesia, antiphlogosis, detumescence and itching-relieving and uses Zingiber corallinum Hance essential oil as the main pharmaceutical ingredient. The product comprises the following components in parts by weight: 1-5 parts of Zingiber corallinum Hance essential oil, 1-5 parts of zanthoxylum oil, 1-5 parts of glycerin, 1-3 parts of Tween 80 and 82-96 parts of alcohol with 50-75% of concentration of volume percent. The preparation method comprises the following steps: pouring all the components in alcohol, and fully shaking to dissolve and mix evenly. The invention has remarkable analgesia effect and also the effects of detumescence, antiphlogosis and sterilization, cures the microcirculatory disturbance, promotes the blood circulation, increases the nutrition of tissue cells, accelerates the self-renewing and self-repairing abilities of the injured tissue cells, takes effect fast, has short treatment period and high recovery rate, and can be used to perform symptomatic treatment to burns and scalds of the superficial layers of the skin, traumatic injuries and skin itches caused by various reasons.
Description
Technical field:
The present invention relates to a kind of externally-applied liniment that can functions of analgesia, antiphlogosis, detumescence and itching-relieving, particularly a kind of is the functions of analgesia, antiphlogosis, detumescence and itching-relieving liniment of main curative effect composition with Rhizoma Zingiberis corallini quintessence oil.
Background technology:
When various external force, physics, biological factor contact body surface, when surpassing the tolerance threshold value of skin, soft tissue teleneuron, soft tissue, blood capillary, will cause the spastic contraction of subcutaneous blood capillary, break, congested, hemorrhage, permeability increases, microcirculation disturbance, histanoxia, particularly congestive edema then appears in traumatic injury, part, damage back, the pain discomfort, the dyskinesia is treated untimely or malpractice, tissue necrosis can occur and infect, have a strong impact on human body health, quality of life.Treat soft tissue injury and mosquito bite dermatitis at present, the medicament of skin pruritus is a lot, but either analgesic effect does not show, or antiinflammation does not reach, or do not have antipruritic effect, and the side effect that also has is big, and generally speaking the scope of application is all relatively limited to.
Summary of the invention:
The purpose of this invention is to provide that a kind of what possess antiinflammatory, detumescence, analgesia, antipruritic function simultaneously is the externally-applied liniment of main curative effect composition with Rhizoma Zingiberis corallini quintessence oil.
The technical scheme that adopts is as follows: take by weighing various raw materials by following parts by weight earlier: 1～5 part of Rhizoma Zingiberis corallini quintessence oil, 1～5 part of Fructus Zanthoxyli oil, 1～5 part of glycerol, 1～3 part of Tween 80, pouring each component into concentration of volume percent is that fully vibration dissolving mixing gets final product in 82～96 parts of 50～75% the ethanol.
Each component weight proportion scope preferably is: 2～3 parts of Rhizoma Zingiberis corallini quintessence oil, 2～4 parts of Fructus Zanthoxyli oil, 1～3 part of glycerol, 1～3 part of Tween 80, concentration of volume percent are 88～92 parts of 50～75% ethanol.
Rhizoma Zingiberis corallini quintessence oil has the function of broad-spectrum antiseptic, analgesia, detumescence, releasing microcirculation disturbance.Its function of easing pain; with the skin superficial scald is example; after skin superficial is scalded and is taken place; the injured skin teleneuron causes violent causalgia; cause to reflexive teleneuron medium (histamine; catecholamine; serotonin; prostaglandins etc.) secretion increases; make damaged part histone catabolic enzyme; the protein catabolite; fibrinoclase (claims plasmin again; a kind of serum albumin permeability factor); hemocyte is situated between plain; Kallidin I materials such as (vasodilatins) is secreted in a large number; blood capillary; lymphatic capillary wall permeability increases; a large amount of tissue fluids are exosmosed; the forwarding function of the histiocyte of injury absorption is simultaneously hindered, and makes to be subjected to the traumatic part to form blister rapidly, in case blister forms; causalgia is promptly ended, and protective response finishes.As scald after the generation promptly to contain the soak of Rhizoma Zingiberis corallini quintessence oil analgesics; the causalgia that scald causes is promptly ended; a series of protective responses that the blocking-up causalgia causes; improve and scald the microcirculation disturbance that causes; improve the wounded tissue cell to scalding the tolerance threshold value that stimulates, strengthen histiocytic self renewal, self-repairing capability; the blocking-up blister takes place, and scalds and cures in no pain.
The Fructus Zanthoxyli oil property and flavor of peppery and warm, tool warming spleen and stomach for dispelling cold, antipruritic function for oral administration are used for epigastric pain, vomiting, diarrhoea etc., and external can be controlled skin pruritus.Solvent is made in the bactericidal action of ethanol tool.Glycerol: be in harmonious proportion, pacify skin.The Tween 80 hydrotropy, skin care, slow release drug effect.These several components all can be buied in market.For the abnormal smells from the patient that improves liniment can add an amount of essence, the amount of adding is that this field ordinary skill people can adjust voluntarily.
Liniment of the present invention is directly smeared, or the spraying affected part, and day is smeared 3～5 times, but is used for skin superficial scald, soak affected part to not drug withdrawal bitterly.
Medicament of the present invention (comprises that skin superficial scalds 80 examples to 200 routine patients, various skin pruritus 60 examples that comprise mosquito bite, skin soft tissue is dampened, articular sprain 60 examples) carried out clinical practice, use the present invention to carry out partial smearing, pain is in time alleviated, detumescence, antiinflammatory and antipruritic evident in efficacy, effective percentage reaches 100%, and is without any side effects.
The invention has the beneficial effects as follows: analgesic effect is remarkable, possesses antiinflammatory, detumescence, itching relieving effect again simultaneously, can remove microcirculation disturbance, and blood circulation promoting quickens the affected part rehabilitation, instant effect, short treating period, and the cure rate height, cost is low, and preparation method is simple and easy to do.Be applicable to that the skin pruritus that the shallow scalds and burns of skin table, traumatic injury and a variety of causes cause all can carry out symptomatic treatment.
Specific embodiment (totally 6 examples)
Embodiment 1:
Earlier by following weight, take by weighing various raw materials: Rhizoma Zingiberis corallini quintessence oil 1kg, Fructus Zanthoxyli oil 1kg, glycerol 1kg, Tween 80 1kg, pouring each component into concentration of volume percent is that fully vibration dissolving mixing gets final product among 50% the ethanol 82kg.
Embodiment 2
Earlier by following weight, take by weighing various raw materials: Rhizoma Zingiberis corallini quintessence oil 5kg, Fructus Zanthoxyli oil 5kg, glycerol 5kg, Tween 80 3kg, pouring each component into concentration of volume percent is that fully vibration dissolving mixing gets final product among 75% the ethanol 96kg.
2～3 parts of embodiment 3 Rhizoma Zingiberis corallini quintessence oil, 2～4 parts of Fructus Zanthoxyli oil, 1～3 part of glycerol, 1～3 part of Tween 80, concentration of volume percent are 88～92 parts of 50～75% ethanol
Earlier by following weight, take by weighing various raw materials: Rhizoma Zingiberis corallini quintessence oil 2kg, Fructus Zanthoxyli oil 2kg, glycerol 1kg, Tween 80 1kg, pouring each component into concentration of volume percent is that fully vibration dissolving mixing gets final product among 65% the ethanol 82kg.
Embodiment 4
Earlier take by weighing various raw materials by following weight: Rhizoma Zingiberis corallini quintessence oil 3kg, Fructus Zanthoxyli oil 4kg, glycerol 3kg, Tween 80 3kg, pouring each component into concentration of volume percent is that fully vibration dissolving mixing gets final product among 70% the ethanol 96kg.
Embodiment 5
Earlier take by weighing various raw materials by following weight: Rhizoma Zingiberis corallini quintessence oil 5kg, Fructus Zanthoxyli oil 2kg, glycerol 3kg, Tween 80 3kg, 75% ethanol 87kg, essence 0.1kg pours each component in the load weighted ethanol container into, and fully vibration dissolving mixing gets final product.
Embodiment 6
Earlier take by weighing various raw materials by following weight: Rhizoma Zingiberis corallini quintessence oil 2kg, Fructus Zanthoxyli oil 5kg, glycerol 4kg, Tween 80 2kg, 50% ethanol 86kg pours each component in the ethanol into, and fully vibration dissolving mixing gets final product.
Claims (2)
1. analgesia, antiinflammatory, detumescence, antipruritic application agent that contains natural Zingiber corallinum Hance essential oil, it is characterized in that preparing as follows: take by weighing various raw materials: 1～5 part of Rhizoma Zingiberis corallini quintessence oil by following parts by weight, 1～5 part of Fructus Zanthoxyli oil, 1～5 part of glycerol, 1～3 part of Tween 80, pouring each component into concentration of volume percent is that fully vibration dissolving mixing gets final product in 82～96 parts of 50～75% the ethanol.
2. analgesia, antiinflammatory, detumescence, antipruritic application agent that contains natural Zingiber corallinum Hance essential oil, the parts by weight that it is characterized in that the component of getting are: 2～3 parts of Rhizoma Zingiberis corallini quintessence oil, 2～4 parts of Fructus Zanthoxyli oil, 1～3 part of glycerol, 1～3 part of Tween 80, concentration of volume percent are 88～92 parts of 50～75% ethanol.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010103508A CN101862441A (en) | 2010-01-29 | 2010-01-29 | Liniment containing natural Zingiber corallinum Hance essential oil with functions of analgesia, antiphlogosis, detumescence and itching-relieving |
| CN2010105610481A CN102008692A (en) | 2010-01-29 | 2010-11-19 | Antalgic swell and inflammation-eliminating itching reliving liniment containing natural essential oil of zingiber corallium hance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010103508A CN101862441A (en) | 2010-01-29 | 2010-01-29 | Liniment containing natural Zingiber corallinum Hance essential oil with functions of analgesia, antiphlogosis, detumescence and itching-relieving |
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| Publication Number | Publication Date |
|---|---|
| CN101862441A true CN101862441A (en) | 2010-10-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010103508A Pending CN101862441A (en) | 2010-01-29 | 2010-01-29 | Liniment containing natural Zingiber corallinum Hance essential oil with functions of analgesia, antiphlogosis, detumescence and itching-relieving |
| CN2010105610481A Pending CN102008692A (en) | 2010-01-29 | 2010-11-19 | Antalgic swell and inflammation-eliminating itching reliving liniment containing natural essential oil of zingiber corallium hance |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105610481A Pending CN102008692A (en) | 2010-01-29 | 2010-11-19 | Antalgic swell and inflammation-eliminating itching reliving liniment containing natural essential oil of zingiber corallium hance |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107982500A (en) * | 2017-11-17 | 2018-05-04 | 贵州苗药生物技术有限公司 | A kind of valerian seedling medicine relaxes network spirit essential oil composition and its preparation method and application |
-
2010
- 2010-01-29 CN CN201010103508A patent/CN101862441A/en active Pending
- 2010-11-19 CN CN2010105610481A patent/CN102008692A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107982500A (en) * | 2017-11-17 | 2018-05-04 | 贵州苗药生物技术有限公司 | A kind of valerian seedling medicine relaxes network spirit essential oil composition and its preparation method and application |
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| Publication number | Publication date |
|---|---|
| CN102008692A (en) | 2011-04-13 |
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Open date: 20101020 |