CN101843256A - Preparation of electric touch-out nano high-valence silver oxides and application thereof as disinfectants - Google Patents

Preparation of electric touch-out nano high-valence silver oxides and application thereof as disinfectants Download PDF

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CN101843256A
CN101843256A CN200910048088A CN200910048088A CN101843256A CN 101843256 A CN101843256 A CN 101843256A CN 200910048088 A CN200910048088 A CN 200910048088A CN 200910048088 A CN200910048088 A CN 200910048088A CN 101843256 A CN101843256 A CN 101843256A
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张兴群
曹张军
许晓东
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
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Abstract

The invention discloses preparation of electric touch-out nano high-valence silver oxides and application thereof as disinfectants. The electric touch-out nano high-valence silver oxides are chemical substances which can kill microorganism efficiently. The preparation method of the oxides used as the disinfectants comprises the following steps of: placing an oxidant of potassium persulfate or sodium persulfate into distillated water; adding sodium hydroxide, diluting and heating (80-90DEG C); adding silver nitrate and keeping the temperature for 30-60min; filtering and flushing with purified water four times to obtain electric touch-out nano high-valence silver oxide particles; dissolving with 5-10 percent ammonia water to obtain 2-5 percent disinfectant mother solution; and processing the disinfectant mother solution into water aqua, effervescent tablets and the like which have the final concentration of 0.3-0.5ppm and can completely kill various microorganisms for test with over 10,000cpu/cc to 100,000cpu/cc within 20min. The invention can be widely applied to various environment disinfections and instrument disinfection of hospitals, schools, swimming pools, bathing pools and other public places, families and the like. The electric touch-out nano high-valence silver oxides have low price of raw materials and simple process; and a preparation has remarkable function on various microorganisms and no harm to the environment and human beings.

Description

Electricity touch-out nano high-valence preparation and as disinfectant applications
Technical field
The invention belongs to antiseptic hygiene epidemic prevention and family expenses technical field, be specifically related to a kind of purposes of electric touch-out nano high-valence bactericide, particularly a kind of sterilization effervescent tablet preparation.
Background technology
Silver is promptly known before 2000 as bactericide, and the researcher measures the relative efficiency of different metal antibacterial efficacy according to experiment, arranges as follows: Ag＞Hg＞Cu＞Cd＞Ni＞Co＞Zn＞Fe＞Ca
Silver participates in the bactericidal activity effect also the existing form of different price key table, Ag 4O 4Deliver as a kind of novel microbial bactericide 52-59 page or leaf on 72 the 3rd phases of volume at soap cosmetics chemical specialties in 1994, this literary composition has shown the bactericidal property of this material brilliance.And different bactericidal properties being arranged by having researched and proposed different price silver, their sterilization relative ability is as follows: Ag 4O 4＞Ag (III)＞Ag (II)＞Ag (I)
U.S. Pat 5211855 is described Ag 4O 4Be a battery, two trivalent silver irons and two monovalence silver ions arranged in the molecular structure after this crystal molecule is subjected to oxidant sodium peroxydisulfate (potassium) activation, they just discharge electronics, are equivalent to 6.4*10 -19Watt/electrical power of rubbing, by electric action of contace poison microorganism is caused death.Trivalent silver constantly discharges electronics and changes divalence silver into, and monovalence silver all can maintain bactericidal activity until changing silver into, and this also gives Ag 4O 4The high-efficient and lasting antibacterial ability.
Reaction principle:
4AgNO 3+2Na 2S 2O 8+8NaOH→Ag 4O 4+4Na 2SO 4+4NaNO 3+6H 2O
Ag 4O 4It is the diamagnetism crystal of semi-conductive, a tool active electrons.Molecular weight is 495.52, and two monovalencies are wherein arranged, and the silver ion of two trivalents is again in conjunction with the novel electron transition compound of four oxygen atoms.Ag (III)-O Ag (I)-O, unit distance equates to be 2.1
Figure B2009100480883D0000021
Ag (III)-Ag (III)=Ag (I)-Ag (I)=3.28
Figure B2009100480883D0000022
Ag (I)-Ag (III)=3.19
Figure B2009100480883D0000023
Each trivalent silver is to pass through dsp 2Electronics and four oxygen atoms form coordinate bond.
People's such as Zhou Guoguang Chinese patent No.200510024521.1 has announced a kind of high price silver synthetic method, and its composition is Ag 2O and Ag 2O 2Mixture.The Chinese patent No.200310105878.3 that Zhang Wen such as levies at the people has announced a kind of silver-colored phosphate inorganic antiseptic of high price and preparation method thereof that contains.Jing Xiaomin has announced the preparation method of carbon-based high valence silver molecule crystal battery in Chinese patent No.200710017828.8, and has tested its application in drinking water system.But these patents have all only been announced the product synthetic method, lack this material property and characterize, and how also do not specify this product using method and bactericidal effect simultaneously.Although above-mentioned patent is recognized high price silver and had than common Nano Silver and the high disinfection vitality of monovalence silver, also recognize its potential use in sterilization simultaneously, formerly patent and fail to provide the concrete technology and the product form of expression of developing product.Therefore more need a kind ofly to expect product technology again to the effect analysis technology, and finally develop the disinfection product formulation from former.The present invention relates to electric touch-out nano high-valence preparation and extension product exploitation, it uses as disinfectant has the efficient sterilizing ability, simultaneously nontoxic, no allergic, not influenced by extraneous other metal ion, and the sterilization persistence is strong.
The objective of the invention is first that sterilizing ability is strong Tetrasilver tetroxide and be applied in public health and home disinfecting field.The present invention has simultaneously announced the technological process of its making aqua and effervescent tablet.
Summary of the invention
The present invention is based on previous work, obtains electric touch-out nano high-valence, is applied in the sterilizations such as public place, family, personal appliance.
The technical solution used in the present invention is to achieve these goals:
1. taking by weighing the 24-90g oxidant crosses (two) potassium sulphate or crosses (two) sodium sulphate in distilled water, add 48-60g potassium hydroxide or sodium hydroxide again, be diluted to 1000ml then, be heated to 80-90 ℃, rolling adds the 1.4g silver nitrate, 80～90 ℃ of insulation 30min, filter, and,, promptly obtain electric touch-out nano high-valence with the unreacted potassium sulphate of flush away (sodium) and potassium nitrate (sodium) and other impurity with pure water rinsing four times.Products obtained therefrom characterizes sees accompanying drawing;
2. preparation type
The present invention can be processed as eco-friendly aqua and effervescent tablet as bactericide.
(1) composition of aqua
Electricity touch-out nano high-valence bactericide 2%
25% ammoniacal liquor 20%
Distilled water 76-78%
(2) composition of effervescent tablet
Sodium bicarbonate 30%
Tartaric acid 30%
Electricity touch-out nano high-valence 0.05%-5%
The molten 5%PVP 40% of alcohol
Get equivalent sodium bicarbonate, tartaric acid mixing, add 0.25-20mg electricity touch-out nano high-valence particle, other adds the alcoholic solution of 5%PVP (polyvinylpyrrolidone) as adhesive, dries 2-4 hour for 80 ℃.Get 0.5-1g with 5-15 pound pressure film-making moulding.
Compared with prior art, the present invention has following have following advantage and beneficial effect:
(1) the present invention uses the new type bactericide Tetrasilver tetroxide first with health and epidemic prevention, and with respect to sodium rice silver of now having used and monovalence silver, bactericidal effect is better, can improve 50-200 doubly.
(2) bactericide of the present invention has broad-spectrum sterilization, and is all effective with multiple microorganism to experiment.
(3) active ingredient is a Tetrasilver tetroxide among the present invention, to environment and human body safety.Formulation is aqua and effervescent tablet, and it is convenient to use.
(4) raw materials for production of bactericide original drug of the present invention and manufactured goods are easy to get, and technology is simple, and cost is low.
Description of drawings
Fig. 1: represent the analysis of electric touch-out nano high-valence heat.Sample has maximum volatilization value respectively near 172.9 ℃ and 457.1 ℃, show that this product is made up of two kinds of compositions, is respectively Ag 2O and Ag 2O 3
Fig. 2: represent the analysis of electric touch-out nano high-valence aqueous solution nanometer.Sample respectively diameter distribution shows that also this product may be made up of two kinds of components near 57.9nm and 217.4nm.
Fig. 3: the electric touch-out nano high-valence sterilization effervescent tablet that expression is made by aforementioned technology, its substance is 0.5-1g, in room temperature, can discharge fully in 1-5 minute during pH7.0.
Fig. 4: expression gained electricity touch-out nano high-valence disinfectant aqua or effervescent tablet bactericidal effect are analyzed, and a is for handling, and b is contrast.
Embodiment:
Below in conjunction with case study on implementation, the present invention is elaborated.
Preparation of case study on implementation 1:2% solution aqua and bactericidal property test
1. take by weighing 24-90g oxidant potassium peroxydisulfate or sodium peroxydisulfate in distilled water, add 48-60g potassium hydroxide or sodium hydroxide again, be diluted to 1000g then, be heated to 80～90 ℃, add the 1.4g silver nitrate mixing that rolls, 80～90 ℃ of insulation 30min filter, and with pure water rinsing four times, to remove potassium sulphate (sodium) and potassium nitrate (sodium) and other impurity.
2. the former powder 2g of power taking touch-out nano high-valence adds 25% concentrated ammonia liquor 20ml, distilled water 80ml, and the following stirring of normal temperature 5-10min extremely electric touch-out nano high-valence dissolves fully.
3. get above-mentioned 2% electric touch-out nano high-valence sample stoste 2.5 μ l and join that (bacteria containing amount is greater than 100 in the 100ml distilled water, 000cpu/cc, test organisms is respectively Escherichia coli, staphylococcus aureus, Candida albicans), left standstill 20 seconds, evenly coat on three aseptic flat boards from wherein getting three samples of 20 μ l at random, cultivated 12-14 hour, colony counting is contrast with non-processor bacterium liquid.The result shows that it all can kill institute examination microorganism 100% in 50 seconds.
4. get above-mentioned 2% electric touch-out nano high-valence sample stoste 7.5ml and join 0.5m 3(bacteria containing amount is greater than 100 in the running water, 000cpu/cc, test organisms is respectively Escherichia coli, staphylococcus aureus, Candida albicans), mixing, after 50 seconds, evenly coat on three aseptic flat boards, cultivated 12-14 hour from wherein getting three samples of 20 μ l at random, colony counting is contrast with non-processor bacterium liquid.The result shows that it all can be in 30 seconds kill institute examination microorganism 100%, and is not subjected to that other composition influences in the running water.
Case study on implementation 2: effervescent tablet preparation and bactericidal property test
1. get equivalent sodium bicarbonate, each 0.5g mixing of tartaric acid, add 2% electric touch-out nano high-valence sample stoste 12.5 μ l, other adds the alcoholic solution of 5%PVP (polyvinylpyrrolidone) as adhesive, dries 2-4 hour for 80 ℃.Get 0.5-1g with 5-15 pound pressure film-making moulding.
2. above-mentioned effervescent tablet is put in 500ml that room temperature places and carries disease germs in the running water that (bacteria containing amount is greater than 100,000cpu/cc, test organisms is respectively Escherichia coli, staphylococcus aureus, Candida albicans), allow effervescent tablet discharge naturally, after 1 minute, evenly coat on three aseptic flat boards, cultivated 12-14 hour from wherein respectively getting 20 μ l at random, colony counting is contrast with non-processor bacterium liquid.The result shows that it all can kill institute examination microorganism 100% in 1 minute.
Case study on implementation 3: effervescent tablet preparation and family, the test of hotel bathtub antiseptic property
1. get equivalent sodium bicarbonate, each 10g mixing of tartaric acid, add 5% electric touch-out nano high-valence sample stoste 20ml, other adds the alcohol of 5%PVP (polyvinylpyrrolidone) as adhesive, dries 2-4 hour for 80 ℃.Divide and get 1g with 10 pounds of pressure film-making moulding.
2. 3 of above-mentioned effervescent tablets are invested at random the 0.5m that room temperature is placed 3Carrying disease germs in the running water, (bacteria containing amount is greater than 10,000cpu/cc, test organisms is respectively Escherichia coli, staphylococcus aureus, Candida albicans), allow effervescent tablet discharge naturally, after 5 minutes, evenly coat on three aseptic flat boards, cultivated 12-14 hour from wherein respectively getting 20 μ l at random, colony counting is contrast with non-processor bacterium liquid.The result shows that it all can kill institute examination microorganism 100% in 5 minutes.

Claims (14)

1. Tetrasilver tetroxide electricity touch-out nano high-valence bactericide exists above-mentioned article enough to give its sterilization idiocratic, and it can be made into sterilization mother liquor or effervescent tablet disinfectant and is applied to corresponding field.
2. the article in the claim 1 are Tetrasilver tetroxides, the mixture that it is made up of two kinds of compounds, and two kinds of compounds are respectively silver sesquioxide and silver oxide.
3. the article of claim 1 are a kind of solid sodium rice inorganic material.
4. according to the described purposes of claim 1, made power taking touch-out nano high-valence thimerosal mother liquor technology is characterized in that:
Take by weighing 24-90g oxidant potassium peroxydisulfate or sodium peroxydisulfate in distilled water, add 48-60g potassium hydroxide or sodium hydroxide again, be diluted to 1000ml then, be heated to 80～90 ℃, rolling to stir adds the 0.5-1.0g silver nitrate down, 80～90 ℃ of insulation 30-60min, filter, and,, promptly obtain electric touch-out nano high-valence particle with the unreacted potassium sulphate of flush away (sodium) and potassium nitrate (sodium) and other impurity with pure water rinsing four times.Obtain the said goods and be dissolved in 5～10% the ammoniacal liquor, prepare 2～5% electric touch-out nano high-valence thimerosal mother liquors.
5. according to the described purposes of claim 1, it is characterized in that the preparation method of described electric touch-out nano high-valence effervescent tablet sterilization formulation may further comprise the steps:
Get equivalent sodium bicarbonate, tartaric acid mixing, add respective amount claim 4 synthesis mother liquids, other adds the alcoholic solution of 5%PVP (polyvinylpyrrolidone) as adhesive, dries 2-4 hour for 80 ℃.Get 0.5-1g with 5-15 pound pressure film-making moulding.
6. the method for the silver formed by silver nitrate of claim 4.
7. in claim 4 oxidant potassium peroxydisulfate or sodium peroxydisulfate.
8. water bath heating temperature to 80 in the claim 4～90 ℃, 80～90 ℃ of insulation 30～60min.
9. purposes according to claim 1 is characterized in that, this antibacterial agent can be machined for the various preparations of various environment disinfecteds such as public places such as hospital, school and family and disinfecting utensils.
10. purposes according to claim 4 is characterized in that, electric touch-out nano high-valence 2%-5%,
11. purposes according to claim 1, right 8 require to be characterised in that sodium bicarbonate, tartaric acid ratio are 1: 1 in the effervescent tablet that solvent is the alcoholic solution of 5%PVP, and contains 0.25mg-50mg electricity touch-out nano high-valence.
12. kit comprises:
A) electric touch-out nano high-valence aqua or effervescent tablet;
B) electric touch-out nano high-valence product is used for the disinfection operation instructions.
13. the kit of claim 12, the finished product packing concentration that wherein comprises electric touch-out nano high-valence aqua is 0.1%-5%.
14. the kit of claim 12, wherein electric touch-out nano high-valence content is 0.25mg-50mg in the effervescent tablet.
CN200910048088A 2009-03-24 2009-03-24 Preparation of electric touch-out nano high-valence silver oxides and application thereof as disinfectants Pending CN101843256A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102091594A (en) * 2011-01-06 2011-06-15 苏州邦安新材料科技有限公司 Process for preparing novel silver loaded active carbon by rheological phase reaction method
CN102173477A (en) * 2011-01-06 2011-09-07 苏州邦安新材料科技有限公司 Preparation technique of novel silver-carried activated carbon by hydrothermal method
CN102321973A (en) * 2011-07-21 2012-01-18 苏州邦安新材料科技有限公司 Silver coating compound and silver coating process for textile
CN109023916A (en) * 2018-08-22 2018-12-18 黄福龙 The production method of sterilization sterilizing base fabric
CN109082920A (en) * 2018-08-22 2018-12-25 黄福龙 The production method of sterilizing paper
CN109096519A (en) * 2018-08-22 2018-12-28 黄福龙 The production method of antibiotic property plastics

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102091594A (en) * 2011-01-06 2011-06-15 苏州邦安新材料科技有限公司 Process for preparing novel silver loaded active carbon by rheological phase reaction method
CN102173477A (en) * 2011-01-06 2011-09-07 苏州邦安新材料科技有限公司 Preparation technique of novel silver-carried activated carbon by hydrothermal method
CN102173477B (en) * 2011-01-06 2014-02-19 苏州泰利三佳纳米科技有限公司 Preparation technique of novel silver-carried activated carbon by hydrothermal method
CN102321973A (en) * 2011-07-21 2012-01-18 苏州邦安新材料科技有限公司 Silver coating compound and silver coating process for textile
CN109023916A (en) * 2018-08-22 2018-12-18 黄福龙 The production method of sterilization sterilizing base fabric
CN109082920A (en) * 2018-08-22 2018-12-25 黄福龙 The production method of sterilizing paper
CN109096519A (en) * 2018-08-22 2018-12-28 黄福龙 The production method of antibiotic property plastics

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Application publication date: 20100929