CN101837100A - Medicinal composition for curing gynecopathy and application thereof - Google Patents
Medicinal composition for curing gynecopathy and application thereof Download PDFInfo
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Abstract
The invention discloses a medicinal composition for curing gynecopathy and application thereof. The medicinal composition is prepared from spreading hedyotis herb, glabrous greenbrier rhizome, shinyleaf pricklyash root, common burreed rhizome (fried with vinegar), gordon euryale seed (fried), red paeony root, Chinese angelica, lightyellow sophora root, golden cypress, root of red-rooted salvia, Mongolian dandelion herb, cinnamomvine and safflower in a certain ratio, and according to a pharmaceutic conventional method, the medicinal composition can be prepared into clinically acceptable oral decoctions, pills, powder, capsules, tablets, particles, drop pills, soft capsules and oral solution. The medicinal composition has the advantages of quite good effects of curing gynecopathy such as cervical erosion, gynecological inflammation and urinary tract infection, high safety of clinical use, high cure rate, base strengthening of Chinese medicaments, less negative effects, safe and effective treatment under the instruction of doctors, and contribution to population.
Description
Technical field
The present invention relates to a kind of medical composition and its use that is used for the treatment of gynaecopathia, particularly a kind of oral Chinese medicine composition and use thereof that is used for the treatment of cervical erosion, gynecological inflammation, urinary tract infection.
Background technology
Cervical erosion, gynecological inflammation, urinary tract infection are the common diseases of gynecological, and sickness rate is high.Cervical erosion belongs to traditional Chinese medical science leukorrhagia category, mainly is because insufficiency of the spleen leading to overabundance of dampness, strongly fragrant heat-transformation of a specified duration, or pathogenic fire derived from stagnation of liver-QI, become damp and hot or bacterial infection due to.And cervical erosion has the trend of canceration, so it is significant to improve the cure rate of cervical erosion.Treatment cervical erosion has several different methods at present, and common methods has naturopathy and Drug therapy, and side effect is big, difficulty is removed limitations such as old complaint but all exist.Gynecological inflammation comprises pelvic inflammatory disease, vaginitis, cervicitis etc.Therapeutic Method commonly used at present has liquid medicine vaginadouche, part to put medicine, oral medication etc., and used medicine is also varied, but clinical efficacy is unsatisfactory, and cure rate is about 50~85% not to be waited.Antibiotic therapy is especially used in chemical medicine treatment, and instant effect but easily produce drug resistance is often because of thoroughly outbreak repeatedly of treatment.
From the therapeutic effect of present this type of gynaecopathia, doctor trained in Western medicine does not still have ideal Therapeutic Method and medicine; The traditional Chinese medical science is with a long history to the treatment of this disease, has accumulated abundant clinical experience, and is evident in efficacy.Chinese medicine has good effect, few side effects, advantages such as easy prolonged application.
Summary of the invention
The present invention aims to provide a kind of pharmaceutical composition and purposes that is used for the treatment of gynaecopathia.
The present invention is achieved through the following technical solutions.
The crude drug composition and the proportioning of pharmaceutical composition of the present invention are as follows:
Herba Hedyotidis Diffusae 20~200 weight portions, Rhizoma Smilacis Glabrae 20~200 weight portions, Radix Zanthoxyli 10~100 weight portions, rhizoma sparganic (processed with vinegar) 10~100 weight portions, Semen Euryales (stir-fry) 20~200 weight portions, Radix Paeoniae Rubra 10~100 weight portions, Radix Angelicae Sinensis 20~200 weight portions, Radix Sophorae Flavescentis 10~100 weight portions, Cortex Phellodendri 10~100 weight portions, Radix Salviae Miltiorrhizae 20~200 weight portions, Herba Taraxaci 10~100 weight portions, Rhizoma Dioscoreae 30~300 weight portions, Flos Carthami 2~20 weight portions.
Crude drug preferred weight part of the invention described above pharmaceutical composition is:
Herba Hedyotidis Diffusae 100 weight portions, Rhizoma Smilacis Glabrae 120 weight portions, Radix Zanthoxyli 60 weight portions, rhizoma sparganic (processed with vinegar) 60 weight portions, Semen Euryales (stir-fry) 100 weight portions, Radix Paeoniae Rubra 65 weight portions, Radix Angelicae Sinensis 100 weight portion Radix Sophorae Flavescentiss 60 weight portions, Cortex Phellodendri 60 weight portions, Radix Salviae Miltiorrhizae 100 weight portions, Herba Taraxaci 60 weight portions, Rhizoma Dioscoreae 120 weight portions, Flos Carthami 5 weight portions.
Crude drug preferred weight part of the invention described above pharmaceutical composition is:
Herba Hedyotidis Diffusae 150 weight portions, Rhizoma Smilacis Glabrae 75 weight portions, Radix Zanthoxyli 75 weight portions, rhizoma sparganic (processed with vinegar) 50 weight portions, Semen Euryales (stir-fry) 75 weight portions, Radix Paeoniae Rubra 75 weight portions, Radix Angelicae Sinensis 75 weight portions, Radix Sophorae Flavescentis 120 weight portions, Cortex Phellodendri 75 weight portions, Radix Salviae Miltiorrhizae 78 weight portions, Herba Taraxaci 50 weight portions, Rhizoma Dioscoreae 100 weight portions, Flos Carthami 2 weight portions.
Pharmaceutical composition of the present invention can be made all peroral dosage forms of acceptable clinically, can be decoction, pill, powder, capsule, tablet, granule, drop pill, soft capsule, oral liquid etc.
Making decoction treatment cervical erosion 150 examples with pharmaceutical composition of the present invention analyzes:
This is organized 150 examples and is patients of cervical ruin at hospital outpatient, the voluntary accepting Drug therapy, and do not do the physics treatment before the treatment.20~47 years old age.All do cervical scraping smear and leucorrhea routine examination before every example treatment, get rid of cervical cancer and infusorian, fungal infection.
The result: the total effective rate of all types of erosions is 88.67%, along with the increase of the course of treatment, curative effect gradually improves, and learns processing when finish the course of treatment by statistics, gently, the rotten to the corn curative effect difference of moderate do not have significance, and the weight degree is rotten to the corn and in, the curative effect difference of severe erosion has highly significant.The total effective rate of various rotten to the corn typings is 88.67%, and wherein simple pure type is 98.11%, and granular pattern is 85.71%, nipple type 69.23%.
Analyze with tablet dose treatment chronic pelvic inflammatory disease 56 examples that pharmaceutical composition of the present invention is made:
This organizes 56 examples, 22~52 years old age, average 35 years old; The course of disease 2 months~3 years.The chronic pelvic inflammatory disease card belongs to retention of heat in the interior.Treat usage with the tablet that the present composition is made: every day 3 times, each 3 (0.45g/ sheet) clothes.Clean in addition both hands and pudendum in sleeping before, get this product and put before the vagina or in the left and right sides fornix each 1, stop using menstrual period, but oral medicine still continues.1 menstrual cycle is 1 course of treatment.Generally do not use other western medicines in treatment during the treatment.As a result this group patient through treat 3~10 courses of treatment (wherein treat 3 the course of treatment person's 39 examples, 4 the course of treatment person's 14 examples, 5 the course of treatment person's 2 examples, 10 the course of treatment person's 1 example), the result cures 38 examples, 13 examples that take a turn for the better, invalid 5 examples, total effective rate 91%.
Treat pyelonephritis 60 routine clinical observations with the granule agent that pharmaceutical composition of the present invention is made:
Patient's 120 examples derive from hospital outpatient and inpatient, are the women, divide equally at random to be treatment group and matched group.60 examples are organized in treatment, and in year at age (39.424-13.49), the course of disease (42.404-41.98) moon, severity extent integration (8.48 ± 2.88) divides; Matched group 60 examples, in year at age (37.90 ± 10.4), the course of disease (48.80 ± 29.87) moon, severity extent integration (7.97 ± 2.94) divides.Symptom before the treatment: treatment group frequent micturition 56 examples, urgent micturition 54 examples, dysurea 47 examples, lower abdomen distension 30 examples, lumbago 44 examples, yellowish urine 54 examples; Matched group frequent micturition 50 examples, urgent micturition 45 examples, dysurea 42 examples, lower abdomen distension 36 examples, lumbago 54 examples, yellowish urine 51 examples.Severity extent before the treatment: slight 5 examples are organized in treatment, moderate 12 examples, severe 43 examples; 6 examples that matched group is slight, moderate 14 examples, severe 40 examples.Two groups of above-mentioned data compare, and difference does not have significance (P all>0.05).Oral granule of the present invention is organized in the Therapeutic Method treatment; Each 6 of the oral FUYANKANG PIAN of matched group, every day 3 times.Be for 6 weeks two groups of courses of treatment.As a result, 60 examples are organized in treatment, 3 examples of fully recovering, produce effects 38 examples, effective 13 examples, invalid 6 examples, cure-remarkable-effectiveness rate 68.33%, total effective rate 90.00%; Matched group 60 examples, 5 examples of fully recovering, produce effects 33 examples, effective 16 examples, invalid 6 examples, cure-remarkable-effectiveness rate 63.33%, total effective rate 90.00%.
As seen, pharmaceutical composition of the present invention has reasonable therapeutical effect to gynaecopathia such as cervical erosion, gynecological inflammation, urinary tract infection.Clinical safety in utilization is good, cure rate is high, and Chinese medicine consolidates, and side effect is little, can effectively thoroughly eradicate old complaint, can treat safely and effectively under physician guidance, is beneficial to popularization.
Specific embodiments
The invention will be further described but be not limited to the present invention below by concrete experimental example and embodiment.
Embodiment 1
Herba Hedyotidis Diffusae 100g, Rhizoma Smilacis Glabrae 120g, Radix Zanthoxyli 60g, rhizoma sparganic (processed with vinegar) 60g, Semen Euryales (stir-fry) 100g, Radix Paeoniae Rubra 65g, Radix Angelicae Sinensis 100g, Radix Sophorae Flavescentis 60g, Cortex Phellodendri 60g, Radix Salviae Miltiorrhizae 100g, Herba Taraxaci 60g, Rhizoma Dioscoreae 120g, Flos Carthami 5g, decoct with water, making decoction takes, amount to amount 10 times, take by 3 doses of every days.
Embodiment 2
Herba Hedyotidis Diffusae 150g, Rhizoma Smilacis Glabrae 75g, Radix Zanthoxyli 75g, rhizoma sparganic (processed with vinegar) 50g, Semen Euryales (stir-fry) 75g, Radix Paeoniae Rubra 75g, Radix Angelicae Sinensis 75g, Radix Sophorae Flavescentis 120g, Cortex Phellodendri 75g, Radix Salviae Miltiorrhizae 78g, Herba Taraxaci 50g, Rhizoma Dioscoreae 100g, Flos Carthami 2g, make 1000 according to a conventional method, by each 3, take every day for 3 times.
Embodiment 3
Herba Hedyotidis Diffusae 120g, Rhizoma Smilacis Glabrae 100g, Radix Zanthoxyli 75g, rhizoma sparganic (processed with vinegar) 50g, Semen Euryales (stir-fry) 75g, Radix Paeoniae Rubra 75g, Radix Angelicae Sinensis 75g, Radix Sophorae Flavescentis 120g, Cortex Phellodendri 75g, Radix Salviae Miltiorrhizae 78g, Herba Taraxaci 50g, Rhizoma Dioscoreae 100g, Flos Carthami 2g, make 30 bags of granules according to a conventional method, by each 1 bag, take every day for 3 times.
Claims (7)
1. pharmaceutical composition for the treatment of gynaecopathia is characterized in that the parts by weight of raw materials of said composition is:
Herba Hedyotidis Diffusae 20~200 weight portion Rhizoma Smilacis Glabraes 20~200 weight portions
Radix Zanthoxyli 10~100 weight portion rhizoma sparganic 10~100 weight portions
Semen Euryales 20~200 weight portion Radix Paeoniae Rubra 10~100 weight portions
Radix Angelicae Sinensis 20~200 weight portion Radix Sophorae Flavescentiss 10~100 weight portions
Cortex Phellodendri 10~100 weight portion Radix Salviae Miltiorrhizaes 20~200 weight portions
Herba Taraxaci 10~100 weight portion Rhizoma Dioscoreaes 30~300 weight portions
Flos Carthami 2~20 weight portions.
2. the pharmaceutical composition of treatment gynaecopathia as claimed in claim 1 is characterized in that the parts by weight of raw materials of said composition is preferably:
Herba Hedyotidis Diffusae 100 weight portion Rhizoma Smilacis Glabraes 120 weight portions
Radix Zanthoxyli 60 weight portion rhizoma sparganic 60 weight portions
Semen Euryales 100 weight portion Radix Paeoniae Rubra 65 weight portions
Radix Angelicae Sinensis 100 weight portion Radix Sophorae Flavescentiss 60 weight portions
Cortex Phellodendri 60 weight portion Radix Salviae Miltiorrhizaes 100 weight portions
Herba Taraxaci 60 weight portion Rhizoma Dioscoreaes 120 weight portions
Flos Carthami 5 weight portions
3. the pharmaceutical composition of treatment gynaecopathia as claimed in claim 1 is characterized in that the parts by weight of raw materials of said composition is preferably:
Herba Hedyotidis Diffusae 150 weight portion Rhizoma Smilacis Glabraes 75 weight portions
Radix Zanthoxyli 75 weight portion rhizoma sparganic 50 weight portions
Semen Euryales 75 weight portion Radix Paeoniae Rubra 75 weight portions
Radix Angelicae Sinensis 75 weight portion Radix Sophorae Flavescentiss 120 weight portions
Cortex Phellodendri 75 weight portion Radix Salviae Miltiorrhizaes 78 weight portions
Herba Taraxaci 50 weight portion Rhizoma Dioscoreaes 100 weight portions
Flos Carthami 2 weight portions.
4. as the pharmaceutical composition of claim 1,2 or 3 described treatment gynaecopathias, it is characterized in that: described Semen Euryales is to fry by the Chinese medicine processing method to process, and described SANLING is by Chinese medicine processing method processed with vinegar mistake.
5. as the pharmaceutical composition of claim 1,2 or 3 described treatment gynaecopathias, it is characterized in that: described compositions can be made all peroral dosage forms of acceptable clinically by practice of pharmacy.
6. the pharmaceutical composition of treatment gynaecopathia as claimed in claim 5 is characterized in that: the described peroral dosage form of acceptable clinically comprises decoction, pill, powder, capsule, tablet, granule, drop pill, soft capsule, oral liquid.
7. as the pharmaceutical composition of claim 1,2 or 3 described treatment gynaecopathias, be used for cervical erosion, gynecological inflammation, urethritis.
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CN200910061217A CN101837100A (en) | 2009-03-20 | 2009-03-20 | Medicinal composition for curing gynecopathy and application thereof |
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CN200910061217A CN101837100A (en) | 2009-03-20 | 2009-03-20 | Medicinal composition for curing gynecopathy and application thereof |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104069353A (en) * | 2014-05-13 | 2014-10-01 | 杜仁波 | Traditional Chinese medicine for treating pelvic inflammation |
CN105596620A (en) * | 2016-01-15 | 2016-05-25 | 张帆 | Chinese herbal medicine for treating miscellaneous gynecological diseases |
CN105596531A (en) * | 2016-01-30 | 2016-05-25 | 朱玉水 | Externally-applied plaster for treating gynecologic inflammation and preparation method thereof |
CN108578508A (en) * | 2018-07-23 | 2018-09-28 | 河南飞航生物科技有限公司 | A kind of herbal mixture ointment is used for the purposes of uterine neck reparation |
CN108653449A (en) * | 2018-08-09 | 2018-10-16 | 河南飞航生物科技有限公司 | A kind of ointment for uterine neck reparation |
CN108686025A (en) * | 2018-07-23 | 2018-10-23 | 河南飞航生物科技有限公司 | A kind of preparation method of ointment for uterine neck reparation |
CN112237615A (en) * | 2020-11-27 | 2021-01-19 | 赵子荣 | Oral medicine for treating leukorrhea |
-
2009
- 2009-03-20 CN CN200910061217A patent/CN101837100A/en active Pending
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104069353A (en) * | 2014-05-13 | 2014-10-01 | 杜仁波 | Traditional Chinese medicine for treating pelvic inflammation |
CN105596620A (en) * | 2016-01-15 | 2016-05-25 | 张帆 | Chinese herbal medicine for treating miscellaneous gynecological diseases |
CN105596531A (en) * | 2016-01-30 | 2016-05-25 | 朱玉水 | Externally-applied plaster for treating gynecologic inflammation and preparation method thereof |
CN108578508A (en) * | 2018-07-23 | 2018-09-28 | 河南飞航生物科技有限公司 | A kind of herbal mixture ointment is used for the purposes of uterine neck reparation |
CN108686025A (en) * | 2018-07-23 | 2018-10-23 | 河南飞航生物科技有限公司 | A kind of preparation method of ointment for uterine neck reparation |
CN108653449A (en) * | 2018-08-09 | 2018-10-16 | 河南飞航生物科技有限公司 | A kind of ointment for uterine neck reparation |
CN112237615A (en) * | 2020-11-27 | 2021-01-19 | 赵子荣 | Oral medicine for treating leukorrhea |
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Application publication date: 20100922 |