CN101836650A - Azoxystrobin-containing sterilization pesticide composition and application thereof - Google Patents
Azoxystrobin-containing sterilization pesticide composition and application thereof Download PDFInfo
- Publication number
- CN101836650A CN101836650A CN 201010189952 CN201010189952A CN101836650A CN 101836650 A CN101836650 A CN 101836650A CN 201010189952 CN201010189952 CN 201010189952 CN 201010189952 A CN201010189952 A CN 201010189952A CN 101836650 A CN101836650 A CN 101836650A
- Authority
- CN
- China
- Prior art keywords
- propamocarb
- fluoxastrobin
- days
- composition
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention relates to an azoxystrobin-containing sterilization pesticide composition and application thereof. The composition comprises azoxystrobin and propamocarb as effective drug ingredients, and an acceptable auxiliary ingredient in pesticide, wherein the weight ratio of the azoxystrobin and the propamocarb as the effective drug ingredients is 1-50:50-1. The test shows that the two effective drug ingredients in the sterilization pesticide composition have obvious synergic effects, is favorable for delaying the generation of drug resistance, reduces dosage, reduces cost and expands the application scope of the drug.
Description
Technical field
The present invention relates to a kind of bactericidal pesticide composition and application thereof of composite form.
Background technology
Downy mildew is by the microbial plant disease of the downy mildew in the fungi, common downy mildew germ can include the standing grain life that causes the millet downy mildew refer to obstruct mould (Sclerospora graminicola), cause Chinese cabbage downy mildew parasitic downy mildew (Peronosporaparasitica), cause downy mildew of lettuce lettuce dish stalk mould (B.remiarlactucae), cause that the Cuba of cucumber downy mildew intends downy mildew (Pseudoperonosporacubensis) etc.Because the variation of field ecosystem and plant disease pesticide resistance strengthen, the harm of downy mildew in recent years has the trend of increasing the weight of, and big continuously throughout the country the generation become a kind of serious plant disease that can cause very big loss to various vegetables and cereal crops.
Although it is various in style to can be used for preventing and treating the bactericide of downy mildew at present, as 58% metalaxyl manganese-zinc wettable powder, 64% Sandofan wetting powder, 58% metalaxyl mancozeb wettable powder etc., all unsatisfactory.And, these medicines are because long-term the repetition or not science use, made that the resistance of Pseudoperonospora cubensis is serious, not only dosage constantly increases, cause the persticide residue height of agricultural product, influence the quality of agricultural product, also do not meet the social current of environmental protection, cause heavy damage and pollution simultaneously, cause a series of vicious circle environment.Therefore, need the pesticide species of environmental protection, satisfy the needs of Future Society.
Summary of the invention
At above-mentioned situation, the present invention will provide the bactericidal pesticide composition of a kind of efficient, low toxicity, environmental protection, to address the above problem.On this basis, the range of application of the corresponding agricultural chemicals of this bactericidal pesticide composition of the present invention preparation can not only effectively be prevented and treated downy mildew, also can be effective to prevent and treat the eqpidemic disease, balck shank of crops such as comprising vegetables, fruit, tobacco etc.
Said this of the present invention contains the bactericidal pesticide composition of Fluoxastrobin, is to be the active drug composition with Fluoxastrobin and Propamocarb, forms jointly with acceptable auxiliary element in the agricultural chemicals, and the part by weight of active drug composition Fluoxastrobin and Propamocarb is 1: 50～50: 1.Wherein, the further preferred weight ratio of active drug composition Fluoxastrobin and Propamocarb is 1: 30～30: 1.
Fluoxastrobin (Azoxystrobin) in the above-mentioned active drug composition, chemical name (E)-2-{2-[6 (2-cyano-benzene oxygen) pyrimidine-4-base oxygen] phenyl }-the 3-methoxy acrylate, structure is shown in (I).Fluoxastrobin is a kind of brand-new methoxy acrylic bactericide, can have protection, treats and root out triple function, and good crop safety and the very outstanding Environmental compatibility of tool.Its mechanism of action is to destroy its energy by the respiration that suppresses fungi to synthesize and loss of life power.The commodity that contain Fluoxastrobin 250 grams per liter suspending agents that use Amici by name reaches at present, is mainly used in diseases such as preventing and treating potato late blight, soybean rust, sponge gourd downy mildew, early blight of tomato, downy mildew of garpe, sigatoka, citrus anthracnose.Because its drug cost height, use not extensively, and application makes the serious resistance of germ generation easily separately.
Propamocarb (Propamocarb) claim Pu Like again; structure is suc as formula shown in (II); belong to the aliphatic category bactericide; low toxicity, safety; has local preferably systemic action; can be absorbed and upwards be delivered to whole strain plant very soon after handling soil, after the cauline leaf spraying is handled, can be played a protective role by rapid absorption of blade by root system.Its mechanism of action is to suppress the phosphoric acid of germ cell membrane component and synthesizing of fatty acid, suppresses mycelial growth and spreads and sporangial formation and spore germination.Be applicable to vegetables such as cucumber, tomato, pimento, lettuce, potato more, and the disease control of various crop such as tobacco, strawberry, flowers, fruit tree.Mostly the type of service of this compound in agricultural chemicals is its hydrochloride.
In above-mentioned composition, acceptable auxiliary element in the said agricultural chemicals, comprise in the present agricultural chemicals existing be extensive use of and not can with said these two kinds of active drug compositions produce chemical actions or to its drug effect performance have adverse effect as conventional ingredients such as auxiliary agents such as dispersant, diffusant, defoamer, wetting agent, disintegrant, excipient.
The practical application form of the bactericidal pesticide composition that the present invention is above-mentioned, can be according to different use needs or applying environment/conditions, by acceptable auxiliary element in said two active drug compositions and the agricultural chemicals, adopt conventional at present agricultural chemicals preparation method, be processed at present operational any in the common pesticides formulations such as wetting powder, water dispersible granules, suspending agent of comprising.Wherein, can be suspension pesticide as the preferred formulations of pesticide, can be applicable to comprising the fungal disease control of crops such as vegetables, fruit, tobacco.For example, the composition of the said formulations of pesticide and typical preparation can be as following.
A. wetting powder (WP).The said preparation medicine is can homodisperse solid powder preparation in water.When wetting powder prepares, except in said active drug composition (former medicine), adding as white carbon, precipitated calcium carbonate, potter's clay, diatomite, outside thinners such as attapulgite or the inert substance, ionic or nonionic surface active agent (wetting agent also can be arranged, dispersant), wetting agent for example, alkylbenzenesulfonate (DBS-Na), alkylnaphthalene sulfonate (drawing back powder), alkylphenol-polyethenoxy base ether sulfate, alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, aliphatic alcohol sulfate, fatty alcohol ethylene oxide adduct sulfonate, the alkyl amide taurate, aliphatic alcohol polyethenoxy base ether (JFC), content are 0.1%～30% (wt, below all herewith); Dispersant such as naphthalene sulfonate, naphthalene or alkyl naphthalene formaldehyde condensate sulfonates (NO, NN0, MF), lignin and derivative sulfonate thereof (M-9, POLYFON etc.), the polyoxyethylene poly-oxygen propylene aether block copolymer, alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate (SOPA), PVA, CMC content 0.1%-30%; Also contain one or more materials among penetrating agent JFC, azone, thiophene ketone, the penetrant t, content is 0.3%-30%; Can also use other auxiliary agents such as stabilizing agent, foam inhibitor, anticaking agent in the usual way.
One or more materials among former medicine and said inert substance, surfactant, bleeding agent, stabilizing agent etc. are mixed, and the dry pulverization process (as comminution by gas stream etc.) through routine can obtain wetting powder.
B. water dispersible granules (WDG).The said preparation medicine is can be in water very fast disintegration, disperse to form the granule of higher suspension dispersion.By said active drug composition, key elements such as auxiliary agent such as the required conventional wetting agent of preparation, dispersant, interleaving agent, disintegrant, stabilizing agent, adhesive and carrier are formed.Its auxiliary agent and carrier, and the compound method of precursor (preformed objects before the granulation) is analogous to wetting powder substantially.
To obtain preformed objects before the granulation by above-mentioned wetting powder processing method, the water that adds 10-15% makes wet granular through the method for extruder grain or rotating granulation, after wet granular oven dry screening, promptly obtains water dispersible granules.
C. suspending agent (SC).Active drug composition, auxiliary element (wetting dispersing agent, thickener, stabilizing agent, pH regulator agent, defoamer, antifreezing agent) etc. is made through the wet method ultramicro grinding.Wetting dispersing agent wherein can be naphthalene or alkyl naphthalene formaldehyde condensate sulfonates (NO, NN0, MF), lignin and derivative sulfonate (M-9, POLYFON etc.) thereof, alkylphenol-polyethenoxy base ether sulfonate, polyoxyethylene polyoxypropylene base ether block copolymers, in alkylphenol-polyethenoxy base phosphate, carboxymethyl cellulose (CMC), polyvinylpyrrolidone (PVP), polyethylene glycol (PEG), the condensed phosphate etc. one or more, content 0.1%-12%; Thickener and stabilizing agent can be in xanthan gum (XG), polyvinyl alcohol (PVA), the Magnesiumaluminumsilicate etc. one or more, content 0.05-0.5%; PH regulator agent and defoamer can add according to circumstances in right amount.
Because active drug composition Fluoxastrobin is different with the mechanism of action of Propamocarb, test shows, can produce synergistic function with said ratio after composite, compare with the single component agricultural chemicals, can significantly strengthen sterilization and control efficiency, can significantly reduce the field dosage, thereby effectively reduce environmental pollution and residue of pesticide, also reduce and produce and use cost, and enlarged the scope of application of medicine, can be used for the disease control of crops such as vegetables, fruit, tobacco.The difference of two kinds of active drug composition mechanism of action also can reduce the single selection pressure to germ simultaneously, the generation that helps overcoming the disease resistance He delay disease drug resistance.
The embodiment of form is described in further detail foregoing of the present invention more by the following examples.But this should be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following example.Do not breaking away under the above-mentioned technological thought situation of the present invention, various replacements or change according to ordinary skill knowledge and customary means are made all should comprise within the scope of the invention.
Embodiment
Example 1: the composite evaluation of pesticide effectiveness of Fluoxastrobin and Propamocarb to cucumber downy mildew
Subjects: bacterium of downy mildew of cucumber (Pseudoperonospora cubensis)
Ye Panfa is adopted in this test.Break into the leaf dish that diameter is 1.5cm with the card punch cucumber leaves that robust growth is intact, 10 in every ware, 3 repetitions, the leaf dish back side floats on the soup of variable concentrations up.The bacterium of downy mildew of cucumber sporangia suspension (containing 50～100 sporangiums) of inoculation 10 μ L on each leaf dish places and cultivates 6～8d in the illumination box (light application time is 16h, and be 8h interlunation, and temperature is 18～20 ℃), carries out state of an illness investigation.Calculate disease index and preventive effect, and use the DPS statistical software and obtain concentration in medicament virulence regression equation and the inhibition.
The cucumber downy mildew stage division is:
Grade scale
0 grade: blade does not have scab;
1 grade: lesion area accounts for below 5% of whole blade area;
3 grades: lesion area accounts for the 6-10% of whole blade area;
5 grades: lesion area accounts for the 11-25% of whole blade area;
7 grades: lesion area accounts for the 26-50% of whole blade area;
9 grades: lesion area accounts for more than 50% of whole blade area.
The drug effect computational methods:
Control efficiency is converted into probability value (Y), and liquor strength (mg/L) converts logarithm value (x) to, calculates concentration EC in virulence equation and the inhibition with method of least squares
50, according to the toxicity index and the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun medicament.
Actual measurement toxicity index (ATI)=(standard medicament EC
50/ reagent agent EC
50) * 100
The percentage composition of B in percentage composition+B medicament toxicity index * mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (the ATI)/theoretical toxicity index (TTI) of mixture] * 100
When CTC≤80, then composition performance is for Hangzhoupro short of money effect, and when 80＜CTC＜120, then the composition performance is summation action, and when CTC 〉=120, then the composition performance is synergistic effect.Evaluation of pesticide effectiveness result is referring to table 1:
Result of the test shows, the composite control cucumber downy mildew of Fluoxastrobin and Propamocarb, proportioning is between 50: 1～1: 50 the time, co-toxicity coefficient is all more than 140, show that it unites use and can have synergistic effect, and proportioning is between 30: 1～1: 30 the time, and co-toxicity coefficient all is higher than 150, and synergistic effect is more obvious.
The serial proportioning of table 1 Fluoxastrobin and Propamocarb is to the indoor harmacological effect measurement result of bacterium of downy mildew of cucumber
| Medicine is formed (Fluoxastrobin: Propamocarb) (wt) | ??EC 50(mg/L) | ??ATI | ??TTI | Co-toxicity coefficient (CTC) |
| Fluoxastrobin | ??1.08 | ??100 | ??/ | ??/ |
| Propamocarb | ??1.10 | ??98 | ??/ | ??/ |
| ??50∶1 | ??0.92 | ??186 | ??133 | ??140 |
| ??30∶1 | ??0.85 | ??198 | ??130 | ??152 |
| ??20∶1 | ??0.82 | ??210 | ??125 | ??168 |
| ??10∶1 | ??0.71 | ??221 | ??128 | ??173 |
| ??5∶1 | ??0.58 | ??268 | ??120 | ??223 |
| ??1∶1 | ??0.61 | ??201 | ??112 | ??179 |
| ??1∶5 | ??0.69 | ??190 | ??109 | ??174 |
| ??1∶10 | ??0.71 | ??188 | ??111 | ??169 |
| ??1∶20 | ??0.74 | ??184 | ??114 | ??161 |
| ??1∶30 | ??0.78 | ??181 | ??120 | ??151 |
| ??1∶50 | ??0.85 | ??149 | ??101 | ??148 |
Example 2: the composite indoor harmacological effect to black shank of Fluoxastrobin and Propamocarb is measured
Subjects: tobacco black shank bacterium (Phytophthora parasitica)
Pot-culture method is adopted in this test.Select for use tobacco potted plant, after seedling grew to 5～6 leaf periods, the selection size was close, growing way is consistent, leaf seedling normal, anosis no worm is standby.The stronger tobacco black shank bacterium of pathogenicity on oat medium, 28 ℃ of following constant temperature culture 6 days are standby.Of the card punch punching of ready tobacco black shank bacterium with diameter 5mm, adopt insect needle slightly to stab first leaf base surface of cigarette strain, the bacterium cake is affixed on the wound, dipping in sterile water with aseptic absorbent cotton covers on it and preserves moisture, then postvaccinal seedling is placed 28 ℃～30 ℃, cultivate in the climatic cabinate of relative moisture more than 95%.After cultivating 10d, investigate the incidence of every strain cigarette seedling, carry out classification according to following standard:
The black shank stage division is:
Grade scale:
0 grade, complete stool is anosis;
1 grade, stem's scab is no more than stem girth 1/2nd, or half is slightly wilting with lower blade, or scab appears in bottom minority blade;
3 grades, stem's scab surpasses 1/2nd of stem girth, or blade more than half is wilting;
5 grades, stem's scab is around stem girth, or 2/3rds is wilting with blade;
7 grades, the whole blades of diseased plant are wilting or withered.
The drug effect computational methods:
Control efficiency is converted into probability value (Y), and liquor strength (mg/L) converts logarithm value (x) to, calculates concentration EC in virulence equation and the inhibition with method of least squares
50, according to the toxicity index and the co-toxicity coefficient (CTC) of the abundant method calculating of Sun Yun medicament.
Actual measurement toxicity index (ATI)=(standard medicament EC
50/ reagent agent EC
50) * 100
The percentage composition of B in percentage composition+B medicament toxicity index * mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (the ATI)/theoretical toxicity index (TTI) of mixture] * 100
When CTC≤80, then composition performance is for Hangzhoupro short of money effect, and when 80＜CTC＜120, then the composition performance is summation action, and when CTC 〉=120, then the composition performance is synergistic effect.Evaluation of pesticide effectiveness result is referring to table 2:
The serial proportioning of table 2 Fluoxastrobin and Propamocarb is to the indoor harmacological effect measurement result of tobacco black shank bacterium
| Medicine is formed (Fluoxastrobin: Propamocarb) (wt) | ??EC 50(mg/L) | ??ATI | ??TTI | Co-toxicity coefficient (CTC) |
| Fluoxastrobin | ??80.6 | ??100 | ??/ | ??/ |
| Propamocarb | ??121.1 | ??150 | ??/ | ??/ |
| ??50∶1 | ??69.9 | ??213 | ??129 | ??165 |
| Medicine is formed (Fluoxastrobin: Propamocarb) (wt) | ??EC 50(mg/L) | ??ATI | ??TTI | Co-toxicity coefficient (CTC) |
| ??30∶1 | ??69.2 | ??225 | ??123 | ??183 |
| ??20∶1 | ??68.1 | ??231 | ??119 | ??194 |
| ??10∶1 | ??66.7 | ??236 | ??115 | ??205 |
| ??5∶1 | ??65.2 | ??243 | ??111 | ??219 |
| ??1∶1 | ??85.6 | ??221 | ??118 | ??187 |
| ??1∶5 | ??90.4 | ??195 | ??112 | ??174 |
| ??1∶10 | ??91.8 | ??199 | ??118 | ??169 |
| ??1∶20 | ??93.5 | ??194 | ??117 | ??166 |
| ??1∶30 | ??95.8 | ??192 | ??118 | ??162 |
| ??1∶50 | ??98.3 | ??180 | ??114 | ??158 |
Result of the test shows, the composite control black shank of Fluoxastrobin and Propamocarb, proportioning is between 50: 1～1: 50 the time, co-toxicity coefficient is all more than 150, show that it unites use and can have synergistic effect, and proportioning is between 30: 1～1: 30 the time, and co-toxicity coefficient all is higher than 160, and synergistic effect is more obvious.
Embodiment 3:31% Fluoxastrobin Propamocarb wetting powder
Form: Fluoxastrobin 30%, Propamocarb 1%, alkylbenzenesulfonate 4%, naphthalene sulfonate 8%, white carbon 6%, kaolin supplies 100%.
Preparation: various active drug compositions and components such as auxiliary element and filler are mixed in the ratio of filling a prescription, after the dry pulverization process of routine, obtain wetting powder.
Application at the control cucumber downy mildew: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).31% Fluoxastrobin Propamocarb wetting powder is sprayed by 1300 times of (Fluoxastrobin valid density is 230.3mg/L, and Propamocarb valid density is 7.7mg/L) thin ups, and the control efficiency of 7 days and 15 days is respectively 86.2%, 81.4% behind the medicine.250 grams per liter Fluoxastrobin suspending agents are by 1000 times (valid density is 250mg/L), 72.2% Propamocarb aqua is by 600 times (valid density is 1203mg/L), uses with quadrat method and uses, and the preventive effect of 7 days and 15 days is respectively 80.1% behind the medicine, 76.7% and 78.8%, 72.3%.The synergistic effect of the composite back of Fluoxastrobin and Propamocarb is obvious, to the preventive effect of cucumber downy mildew significantly better than single agent.Concrete outcome sees Table 3.
Table 331% Fluoxastrobin Propamocarb wetting powder is to the field efficacy measurement result of cucumber downy mildew
| The medicament title | Effective ingredient consumption (mg/L) | Preventive effect after 7 days (%) | Preventive effect after 15 days (%) |
| 31% Fluoxastrobin Propamocarb | ??238(230.3+7.7) | ?86.2 | ??81.4 |
| 250 grams per liter Fluoxastrobins | ??250 | ?80.1 | ??76.7 |
| 72.2% Propamocarb | ??1203 | ?78.8 | ??72.3 |
Embodiment 4:33% Fluoxastrobin Propamocarb wetting powder
Form: Fluoxastrobin 30%, Propamocarb 3%, alkyl sulfate 4%, carboxylate 7%, white carbon 10%, citric acid 0.5%, diatomite complements to 100%.
Preparation: with embodiment 3.
Application at the control tomato late blight: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).33% Fluoxastrobin Propamocarb wetting powder is sprayed by 1400 times of (Fluoxastrobin valid density is 214.5mg/L, and Propamocarb valid density is 21.5mg/L) thin ups, and the control efficiency of 7 days and 15 days is respectively 85.1%, 80.2% behind the medicine.250 grams per liter Fluoxastrobin suspending agents by 1000 times (valid density is 250mg/L) and 72.2% Propamocarb aqua by 600 times (valid density is 1203mg/L), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 76.9%, 70.5% and 78.3%, 71.1% behind the medicine.The synergistic effect of the composite back of Fluoxastrobin and Propamocarb is obvious, to the preventive effect of tomato late blight significantly better than single agent.Concrete outcome sees Table 4.
Table 4 33% Fluoxastrobin Propamocarb wetting powder is to the field efficacy measurement result of tomato late blight
| The medicament title | Effective ingredient consumption (mg/L) | Preventive effect after 7 days (%) | Preventive effect after 15 days (%) |
| 33% Fluoxastrobin Propamocarb | ??236(214.5+21.5) | ?85.1 | ??80.2 |
| 250 grams per liter Fluoxastrobins | ??250 | ?76.9 | ??70.5 |
| 72.2% Propamocarb | ??1203 | ?78.3 | ??71.1 |
Embodiment 5:42% Fluoxastrobin Propamocarb water dispersible granules
Form: Fluoxastrobin 40%, Propamocarb 2%, alkylsulfonate 6%, alkyl sulfate 8%, white carbon 6%, anhydrous sodium sulfate 15%, kaolin supplies 100%.
Preparation: each composition is mixed, and preformed objects before comminution by gas stream becomes granulation adds suitable quantity of water again and mixes extruder grain in a usual manner.Obtain water dispersible granules after the drying screening.
Preventing and treating the application of potato late blight: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).42% Fluoxastrobin Propamocarb water dispersible granules is sprayed by 1800 times of (Fluoxastrobin valid density is 222mg/L, and Propamocarb valid density is 11mg/L) thin ups, and the control efficiency of 7 days and 15 days is respectively 83.2%, 80.0% behind the medicine.250 grams per liter Fluoxastrobin suspending agents by 1000 times (valid density is 250mg/L) and 72.2% Propamocarb aqua by 600 times (valid density is 1203mg/L), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 72.5%, 68.5% and 71.3%, 65.2% behind the medicine.The synergistic effect of the composite back of Fluoxastrobin and Propamocarb is obvious, to the preventive effect of potato late blight significantly better than single agent.Concrete outcome sees Table 5.
Table 5 42% Fluoxastrobin Propamocarb water dispersible granules is to the field efficacy measurement result of potato late blight
| The medicament title | Effective ingredient consumption (mg/L) | Preventive effect after 7 days (%) | Preventive effect after 15 days (%) |
| 42% Fluoxastrobin Propamocarb | ??233(222+11) | ?83.2 | ??80.0 |
| 250 grams per liter Fluoxastrobins | ??250 | ?72.5 | ??68.5 |
| 72.2% Propamocarb | ??1203 | ?71.3 | ??65.2 |
Embodiment 6:32% Fluoxastrobin Propamocarb water dispersible granules
Form: Fluoxastrobin 30%, Propamocarb 2%, alkylbenzenesulfonate 5%, lignin benzene sulfonate 9%, white carbon 8%, bentonite supplies 100%.
Preparation: with embodiment 5
Application at the control oilseed rape downy mildew: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).32% Fluoxastrobin Propamocarb water dispersible granules is sprayed by 1400 times of (Fluoxastrobin valid density is 214.7mg/L, and Propamocarb valid density is 14.3mg/L) thin ups, and the control efficiency of 7 days and 15 days is respectively 90.5%, 84.6% behind the medicine.250 grams per liter Fluoxastrobin suspending agents by 1000 times (valid density is 250mg/L) and 72.2% Propamocarb aqua by 600 times (valid density is 1203mg/L), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 85.3%, 80.4% and 83.2%, 74.8% behind the medicine.The synergistic effect of the composite back of Fluoxastrobin and Propamocarb is obvious, to the preventive effect of oilseed rape downy mildew significantly better than single agent.Concrete outcome sees Table 6.
Table 6 32% Fluoxastrobin Propamocarb water dispersible granules is to the field efficacy measurement result of oilseed rape downy mildew
| The medicament title | Effective ingredient consumption (mg/L) | Preventive effect after 7 days (%) | Preventive effect after 15 days (%) |
| 32% Fluoxastrobin Propamocarb | ??229(214.7+14.3) | ?90.5 | ??84.6 |
| 250 grams per liter Fluoxastrobins | ??250 | ?85.3 | ??80.4 |
| 72.2% Propamocarb | ??1203 | ?83.2 | ??74.8 |
Embodiment 7:40% Fluoxastrobin Propamocarb suspending agent
Form: Fluoxastrobin 20%, Propamocarb 20%, methyl naphthalene sulfonate formaldehyde condensate 10%, xanthans 0.5%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation: each composition mixes in will filling a prescription, and obtains suspending agent in a usual manner after grinding and/or high speed shear.
Preventing and treating the application of downy mildew of garpe: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).40% Fluoxastrobin Propamocarb is sprayed by 1000 times of (Fluoxastrobin valid density is 200mg/L, and Propamocarb valid density is 200mg/L) thin ups, and the control efficiency of 7 days and 15 days is respectively 92.5%, 86.3% behind the medicine.250 grams per liter Fluoxastrobin suspending agents by 1000 times (valid density is 250mg/L) and 72.2% Propamocarb aqua by 600 times (valid density is 1203mg/L), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 82.9%, 76.6% and 80.8%, 73.4% behind the medicine.The synergistic effect of the composite back of Fluoxastrobin and Propamocarb is obvious, to the preventive effect of downy mildew of garpe significantly better than single agent.Concrete outcome sees Table 7.
Table 7 40% Fluoxastrobin Propamocarb suspending agent is to the field efficacy measurement result of downy mildew of garpe
| The medicament title | Effective ingredient consumption (mg/L) | Preventive effect after 7 days (%) | Preventive effect after 15 days (%) |
| 40% Fluoxastrobin Propamocarb | ??400(200+200) | ?92.5 | ??86.3 |
| 250 grams per liter Fluoxastrobins | ??250 | ?82.9 | ??76.6 |
| 72.2% Propamocarb | ??1203 | ?80.8 | ??73.4 |
Embodiment 8:44% Fluoxastrobin Propamocarb suspending agent
Form: Fluoxastrobin 4%, Propamocarb 40%, methyl naphthalene sulfonate formaldehyde condensate 10%, xanthans 0.6%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation: with embodiment 7.
Application at the control black shank: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).44% Fluoxastrobin Propamocarb is sprayed by 550 times of (Fluoxastrobin valid density is 72.7mg/L, and Propamocarb valid density is 727.3mg/L) thin ups, and the control efficiency of 7 days and 15 days is respectively 86.1%, 80.2% behind the medicine.250 grams per liter Fluoxastrobin suspending agents by 1000 times (valid density is 250mg/L) and 72.2% Propamocarb aqua by 600 times (valid density is 1203mg/L), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 76.9%, 70.2% and 78.5%, 71.2% behind the medicine.The synergistic effect of the composite back of Fluoxastrobin and Propamocarb is obvious, to the preventive effect of black shank significantly better than single agent.Concrete outcome sees Table 8.
Table 8 44% Fluoxastrobin Propamocarb suspending agent is to the field efficacy measurement result of black shank
| The medicament title | Effective ingredient consumption (mg/L) | Preventive effect after 7 days (%) | Preventive effect after 15 days (%) |
| 44% Fluoxastrobin Propamocarb | ??800(72.7+727.3) | ?86.1 | ??80.2 |
| 250 grams per liter Fluoxastrobins | ??250 | ?76.9 | ??70.2 |
| 72.2% Propamocarb | ??1203 | ?78.5 | ??71.2 |
Embodiment 9:31% Fluoxastrobin Propamocarb suspending agent
Form: Fluoxastrobin 1%, Propamocarb 30%, methyl naphthalene sulfonate formaldehyde condensate 10%, xanthans 0.65%, bentonite 1%, glycerine 5%, water complements to 100%.
Preparation: with embodiment 7.
Application at the control capsicum epidemic disease: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).31% Fluoxastrobin Propamocarb is sprayed by 300 times of (Fluoxastrobin valid density is 33mg/L, and Propamocarb valid density is 1000mg/L) thin ups, and the control efficiency of 7 days and 15 days is respectively 90.1%, 85.9% behind the medicine.250 grams per liter Fluoxastrobin suspending agents by 1000 times (valid density is 250mg/L) and 72.2% Propamocarb aqua by 600 times (valid density is 1203mg/L), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 84.9%, 80.2% and 86.5%, 79.9% behind the medicine.The synergistic effect of the composite back of Fluoxastrobin and Propamocarb is obvious, to the preventive effect of capsicum epidemic disease significantly better than single agent.Concrete outcome sees Table 9.
Table 9 31% Fluoxastrobin Propamocarb suspending agent is to the field efficacy measurement result of capsicum epidemic disease
| The medicament title | Effective ingredient consumption (mg/L) | Preventive effect after 7 days (%) | Preventive effect after 15 days (%) |
| 31% Fluoxastrobin Propamocarb | ??1033(33+1000) | ?90.1 | ??85.9 |
| 250 grams per liter Fluoxastrobins | ??250 | ?84.9 | ??80.2 |
| 72.2% Propamocarb | ??1203 | ?86.5 | ??79.9 |
Embodiment 10:51% Fluoxastrobin Propamocarb water dispersible granules
Form: Fluoxastrobin 50%, Propamocarb 1%, alkylbenzenesulfonate 6%, lignin benzene sulfonate 9%, white carbon 5%, bentonite supplies 100%.
Preparation: with embodiment 5
Application at the control downy mildew of lettuce: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).51% Fluoxastrobin Propamocarb water dispersible granules is sprayed by 2200 times of (Fluoxastrobin valid density is 227mg/L, and Propamocarb valid density is 5mg/L) thin ups, and the control efficiency of 7 days and 15 days is respectively 88.9%, 82.5% behind the medicine.250 grams per liter Fluoxastrobin suspending agents by 1000 times (valid density is 250mg/L) and 72.2% Propamocarb aqua by 600 times (valid density is 1203mg/L), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 82.1%, 76.3% and 81.1%, 73.2% behind the medicine.The synergistic effect of the composite back of Fluoxastrobin and Propamocarb is obvious, to the preventive effect of downy mildew of lettuce significantly better than single agent.Concrete outcome sees Table 10.
Table 10 51% Fluoxastrobin Propamocarb water dispersible granules is to the field efficacy measurement result of downy mildew of lettuce
| The medicament title | Effective ingredient consumption (mg/L) | Preventive effect after 7 days (%) | Preventive effect after 15 days (%) |
| 51% Fluoxastrobin Propamocarb | ??232(227+5) | ?88.9 | ??82.5 |
| 250 grams per liter Fluoxastrobins | ??250 | ?82.1 | ??76.3 |
| 72.2% Propamocarb | ??1203 | ?81.1 | ??73.2 |
Embodiment 11:25.5% Fluoxastrobin Propamocarb suspending agent
Form: Fluoxastrobin 0.5%, Propamocarb 25%, methyl naphthalene sulfonate formaldehyde condensate 8%, xanthans 0.5%, aluminium-magnesium silicate 1%, glycerine 6%, water complements to 100%.
Preparation: with embodiment 7.
Application in control wax gourd downy mildew: test is carried out with reference to People's Republic of China's standard (pesticide field efficacy medicine test criterion).25.5% Fluoxastrobin Propamocarb is sprayed by 250 times of (Fluoxastrobin valid density is 20mg/L, and Propamocarb valid density is 1000mg/L) thin ups, and the control efficiency of 7 days and 15 days is respectively 90.2%, 82.4% behind the medicine.250 grams per liter Fluoxastrobin suspending agents by 1000 times (valid density is 250mg/L) and 72.2% Propamocarb aqua by 600 times (valid density is 1203mg/L), with using with quadrat method, the preventive effect of 7 days and 15 days is respectively 81.9%, 76.3% and 79.9%, 74.6% behind the medicine.The synergistic effect of the composite back of Fluoxastrobin and Propamocarb is obvious, to the preventive effect of wax gourd downy mildew significantly better than single agent.Concrete outcome sees Table 11.
Table 11 25.5% Fluoxastrobin Propamocarb suspending agent is to the field efficacy measurement result of wax gourd downy mildew
| The medicament title | Effective ingredient consumption (mg/L) | Preventive effect after 7 days (%) | Preventive effect after 15 days (%) |
| 25.5% Fluoxastrobin Propamocarb | ??1020(20+1000) | ?90.2 | ??82.4 |
| 250 grams per liter Fluoxastrobins | ??250 | ?81.9 | ??76.3 |
| 72.2% Propamocarb | ??1203 | ?79.9 | ??74.6 |
Claims (4)
1. a bactericidal pesticide composition that contains Fluoxastrobin is characterized in that with Fluoxastrobin and Propamocarb be the active drug composition, forms jointly with acceptable auxiliary element in the agricultural chemicals, and the part by weight of active drug composition Fluoxastrobin and Propamocarb is 1: 50～50: 1.
2. bactericidal pesticide composition as claimed in claim 1, the part by weight that it is characterized in that said active drug composition Fluoxastrobin and Propamocarb is 1: 30～30: 1.
3. bactericidal pesticide composition as claimed in claim 1 or 2 is characterized in that common operational suspending agent, wetting powder, the pesticide water dispersible granule formed of acceptable auxiliary element in said active drug composition and the agricultural chemicals.
4. the described bactericidal pesticide composition that contains Fluoxastrobin of one of claim 1 to 3 comprises the application in the farm crop fungus diseases such as vegetables, fruit, tobacco in control.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010189952 CN101836650A (en) | 2010-06-02 | 2010-06-02 | Azoxystrobin-containing sterilization pesticide composition and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010189952 CN101836650A (en) | 2010-06-02 | 2010-06-02 | Azoxystrobin-containing sterilization pesticide composition and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101836650A true CN101836650A (en) | 2010-09-22 |
Family
ID=42740533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201010189952 Pending CN101836650A (en) | 2010-06-02 | 2010-06-02 | Azoxystrobin-containing sterilization pesticide composition and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101836650A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102217619A (en) * | 2011-04-13 | 2011-10-19 | 陕西汤普森生物科技有限公司 | Bactericidal composition containing enostroburin and carbamates compound |
| CN102626081A (en) * | 2012-04-12 | 2012-08-08 | 广西田园生化股份有限公司 | Ultralow-volume liquid for preventing and treating oomycetes disease |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0897664A1 (en) * | 1997-08-22 | 1999-02-24 | Chimac-Agriphar S.A. | Fungicidal composition |
| CN101473830A (en) * | 2009-01-16 | 2009-07-08 | 利尔化学股份有限公司 | Sterilizing agricultural chemical composition containing amistar |
-
2010
- 2010-06-02 CN CN 201010189952 patent/CN101836650A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0897664A1 (en) * | 1997-08-22 | 1999-02-24 | Chimac-Agriphar S.A. | Fungicidal composition |
| CN101473830A (en) * | 2009-01-16 | 2009-07-08 | 利尔化学股份有限公司 | Sterilizing agricultural chemical composition containing amistar |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102217619A (en) * | 2011-04-13 | 2011-10-19 | 陕西汤普森生物科技有限公司 | Bactericidal composition containing enostroburin and carbamates compound |
| CN102217619B (en) * | 2011-04-13 | 2014-06-18 | 陕西汤普森生物科技有限公司 | Bactericidal composition containing enostroburin and carbamates compound |
| CN102626081A (en) * | 2012-04-12 | 2012-08-08 | 广西田园生化股份有限公司 | Ultralow-volume liquid for preventing and treating oomycetes disease |
| CN102626081B (en) * | 2012-04-12 | 2013-07-10 | 广西田园生化股份有限公司 | Ultralow-volume liquid for preventing and treating oomycetes disease |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101822255B (en) | Sterilization compound containing ZJ0712 | |
| CN101822251A (en) | Sterilization compound containing ZJ0712 | |
| CN101690490A (en) | Bactericidal composition compounded by bromothalonil and methoxy acrylic acid esters | |
| CN103053561B (en) | Benthiavalicarb isopropyl containing bactericidal composition | |
| CN101653139A (en) | Compound bactericidal composition containing boscalid | |
| CN101755777B (en) | Compound for preventing plant oomycetes disease | |
| CN101836634B (en) | Sterilizing pesticide composition containing azoxystrobin as well as application thereof | |
| CN101263821B (en) | Sterilizing composition | |
| CN101836650A (en) | Azoxystrobin-containing sterilization pesticide composition and application thereof | |
| CN103027075B (en) | Fungicide composition containing sulphur | |
| CN101953347A (en) | Pesticide composition and application thereof | |
| CN101822256A (en) | Sterilization compound containing ZJ0712 | |
| CN105284868B (en) | A kind of bactericidal composition containing oxalic acid copper diacetonamine | |
| CN101731238B (en) | Acibenzolar-containing sterilizing composition | |
| CN104430491B (en) | A kind of bactericidal composition containing oxalic acid copper diacetonamine | |
| CN103947649B (en) | A kind of composition pesticide containing glyoxalin and kasugarnycin | |
| CN104705344A (en) | Sulfur-containing bactericidal agent composition and application thereof | |
| CN114766492B (en) | Pesticide composition containing bixafen and application thereof | |
| CN107853309A (en) | A kind of composition pesticide comprising folpet and dimethomorph | |
| CN102037980A (en) | Bactericidal pesticide composition | |
| CN101755787B (en) | Fungicidal composition containing fenoxanil | |
| CN101690488A (en) | Bactericidal composition for agricultural land | |
| CN101822259A (en) | Sterilization compound containing ZJ0712 | |
| CN103947659B (en) | A kind of composition pesticide containing propamocarb and kasugarnycin | |
| CN104351243B (en) | A kind of bactericidal composition containing oxalic acid copper diacetonamine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20100922 |