CN101810792A

CN101810792A - Chinese medicinal composition for treating kidney failure diseases and preparation method thereof

Info

Publication number: CN101810792A
Application number: CN200910309173A
Authority: CN
Inventors: 王峰
Original assignee: Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
Current assignee: Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
Priority date: 2009-10-30
Filing date: 2009-10-30
Publication date: 2010-08-25
Anticipated expiration: 2029-10-30
Also published as: CN101810792B

Abstract

The invention discloses a novel Chinese medicinal composition for treating kidney failure diseases and a preparation method thereof. The Chinese medicinal composition mainly comprises the following raw material medicaments: medlar, American ginseng, campanumaea pilosula, raw astragalus, pantotrichum, common yam rhizome, sea horse, medicinal indianmulberry root, cordyceps sinensis, lucid ganoderma, south dodder seed, gordon euryale seed, eucommia bark, radix rehmanniae preparata, Chinese angelica, white paeony root, cochinchnese asparagus root, glossy privet fruit, amur corktree bark, Indian buead, gardenia, plantain seed, longhairy antenoron herb, talc and oriental waterplantain rhizome. The Chinese medicinal composition can be prepared into any common oral preparation by the conventional Chinese medicinal preparation method. The Chinese medicinal composition can obviously improve symptoms such as edemaofface, edema of limbs, inability to get food down, bradypsychia, uroschesis, creatinine, albuminuria, dreaminess, insomnia and the like, and can improve various complications which seriously influence health and life and even cause depth such as infection, diseases of cardiovascular systems, nervous systems and digestive systems, electrolyte disturbance, metabolic acidosis and the like caused by renal function hydrolysis. The Chinese medicinal composition has the advantages of exact clinical effects, obvious curative effect, quick response, low cost, basically no toxic or side effects and the like because the Chinese medicinal composition basically combines medicaments having homology of medicament and food specified in national formulary.

Description

A kind of Chinese medicine composition for the treatment of kidney failure diseases and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of kidney failure diseases.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment kidney failure diseases of crude drug with the Chinese herbal medicine.

Background technology

Renal ischaemia, nephrotoxicity material act on chronic nephropathy due to the kidney and the various cause of disease and are developed to and all can cause renal failure late period.In the initial period of renal failure, usually without any symptom, yet, when renal function when completely losing, tangible health can occur changes and illness symptom, treat timely and effectively as not taking, the normal multiple complication that has a strong impact on Health and Living even cause death of infection, cardiovascular system diseases, nervous system, digestive system, electrolyte disturbance, metabolic acidosis or the like that easily causes, the clinical onset rate has the trend of continuous rising in recent years.

Modern medicine is generally taked the http://www.sjzsbyy.com/xueyetouxi.html that dialyses, blood transfusion, hormone and alternative drugs, Therapeutic Method such as renal transplantation http://www.sjzsbyy.com/niaoduzheng/txyz/, but up to the present, above-mentioned therapy all exists masty problem, costly, side effect is big, the patient is difficult for accepting, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment renal failure, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical the accent, emergency is taken in concurrently, filters out clearing away heat-damp and promoting diuresis, warming the kidney and strengthening the spleen, set upright tonify deficiency, the natural plant of blood circulation promoting and blood stasis dispelling, according to the theory of Chinese medical science prescription, be prepared from according to certain weight proportion.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment renal failure that toxic and side effects is minimum is provided.

Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.

Summary of the invention

Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment kidney failure diseases of evident in efficacy, with low cost, almost non-toxic side effect is provided.

The technical problem of the desired solution of the present invention realizes by following technological approaches.

A kind of Chinese medicine composition for the treatment of kidney failure diseases of the present invention, the component of main following weight portion is formed:

Fructus Lycii 1～50 gram, Radix Panacis Quinquefolii 1～20 gram, Radix Codonopsis 1～50 gram, Radix Astragali 1～50 gram, Cornu Cervi Pantotrichum 1～30 gram, the Rhizoma Atractylodis Macrocephalae 1～30 gram, Rhizoma Dioscoreae 1～50 gram, Hippocampus 1～20 gram, Radix Morindae Officinalis 1～30 gram, Cordyceps 1～30 gram, Semen Ziziphi Spinosae 1～30 gram, Radix Polygalae 1～30 gram, Ganoderma 1～30 gram, Herba Cistanches 1～40 gram, Semen Cuscutae 1～30 gram, Semen Euryales 1～40 gram, the Cortex Eucommiae 1～30 gram, Radix Rehmanniae Preparata 1～40 gram, Radix Angelicae Sinensis 1～40 gram, the Radix Paeoniae Alba 1～50 gram, Arillus Longan 1～30 gram, Radix Asparagi 1～40 gram, Fructus Ligustri Lucidi 1～30 gram, Fructus Tritici Levis 1～30 gram, Radix Ephedrae 1～30 gram, Fructus Corni 1～40 gram, Fructus Rosae Laevigatae 1～30 gram, Endoconcha Sepiae 1～40 gram, Radix Trichosanthis 1～40 gram.

Be preferably:

Fructus Lycii 30 grams, Radix Panacis Quinquefolii 10 grams, Radix Codonopsis 20 grams, Radix Astragali 30 grams, Cornu Cervi Pantotrichum 10 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Rhizoma Dioscoreae 30 grams, Hippocampus 10 grams, Radix Morindae Officinalis 15 grams, Cordyceps 10 grams, Semen Ziziphi Spinosae 12 grams, Radix Polygalae 15 grams, Ganoderma 10 grams, Herba Cistanches 15 grams, Semen Cuscutae 15 grams, Semen Euryales 20 grams, the Cortex Eucommiae 15 grams, Radix Rehmanniae Preparata 15 grams, Radix Angelicae Sinensis 20 grams, the Radix Paeoniae Alba 30 grams, Arillus Longan 15 grams, Radix Asparagi 20 grams, Fructus Ligustri Lucidi 15 grams, Fructus Tritici Levis 15 grams, Radix Ephedrae 10 grams, Fructus Corni 20 grams, Fructus Rosae Laevigatae 15 grams, Endoconcha Sepiae 30 grams, Radix Trichosanthis 30 grams.

The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:

Colla Corii Asini 1～30 gram, the Radix Paeoniae Alba 1～50 gram, Cortex Phellodendri～30 grams, Poria 1～50 gram, Fructus Gardeniae 1～30 gram, Radix Scrophulariae 1～30 gram, Herba Dendrobii 1～30 gram, Rhizoma Polygonati Odorati 1～30 gram, Semen Plantaginis 1～30 gram, Herba Lysimachiae 1～30 gram, Talcum 1～40 gram, Rhizoma Alismatis 1～30 gram, Radix Et Rhizoma Rhei 1～30 gram, Fructus Schisandrae Chinensis 1～30 gram, Semen Ginkgo 1～40 gram, Folium Ginkgo 1～30 gram, Semen Myristicae 1～30 gram, Fructus Alpiniae Oxyphyllae 1～40 gram.

Be preferably:

Colla Corii Asini 15 grams, the Radix Paeoniae Alba 30 grams, Cortex Phellodendri 20 grams, Poria 30 grams, Fructus Gardeniae 15 grams, Radix Scrophulariae 20 grams, Herba Dendrobii 15 grams, Rhizoma Polygonati Odorati 15 grams, Semen Plantaginis 15 grams, Herba Lysimachiae 20 grams, Talcum 30 grams, Rhizoma Alismatis 20 grams, Radix Et Rhizoma Rhei 30 grams, Fructus Schisandrae Chinensis 20 grams, Semen Ginkgo 15 grams, Folium Ginkgo 15 grams, Semen Myristicae 15 grams, Fructus Alpiniae Oxyphyllae 20 grams.

Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.

Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.This is the important content of Thailand one and Pu (Beijing) Chinese medicine academy patent strategy.

The structure of Thailand one and Pu patent strategy is convenient to Chinese medicine and is realized standardization, scale, industrialization, modernization and industrialization.For traditional Chinese medicine development has been opened up a road that meets the Chinese medicine self-law with innovation.

The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.

Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2～5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.

The treatment that the present invention is directed to the kidney failure diseases patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.

The specific embodiment

Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.

The preparation of [embodiment 1] capsule

Take by weighing each raw material by following weight portion: Fructus Lycii 30 grams, Radix Panacis Quinquefolii 10 grams, Radix Codonopsis 20 grams, Radix Astragali 30 grams, Cornu Cervi Pantotrichum 10 grams, Radix Morindae Officinalis 15 grams, Cordyceps 10 grams, Semen Ziziphi Spinosae 12 grams, Radix Polygalae 15 grams, Ganoderma 10 grams, Herba Cistanches 15 grams, Semen Cuscutae 15 grams, Semen Euryales 20 grams, the Cortex Eucommiae 15 grams, Arillus Longan 15 grams, Radix Asparagi 20 grams, Fructus Ligustri Lucidi 15 grams, Fructus Corni 20 grams, Fructus Rosae Laevigatae 15 grams, Radix Trichosanthis 30 grams, Cortex Phellodendri 20 grams, Poria 30 grams, Herba Dendrobii 15 grams, Rhizoma Polygonati Odorati 15 grams, Semen Plantaginis 15 grams, Herba Lysimachiae 20 grams, Talcum 30 grams, Rhizoma Alismatis 20 grams, Radix Et Rhizoma Rhei 30 grams, Fructus Schisandrae Chinensis 20 grams, Semen Myristicae 15 grams.

Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.

The preparation of [embodiment 2] granule

Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.

The preparation of [embodiment 3] tablet

Take by weighing each raw material according to following weight portion: Fructus Lycii 30 grams, Radix Panacis Quinquefolii 10 grams, Radix Codonopsis 20 grams, Radix Astragali 30 grams, Cornu Cervi Pantotrichum 10 grams, Radix Morindae Officinalis 15 grams, Cordyceps 10 grams, Semen Ziziphi Spinosae 12 grams, Radix Polygalae 15 grams, Ganoderma 10 grams, Herba Cistanches 15 grams, Semen Cuscutae 15 grams, Semen Euryales 20 grams, the Cortex Eucommiae 15 grams, Arillus Longan 15 grams, Radix Asparagi 20 grams, Fructus Ligustri Lucidi 15 grams, Fructus Corni 20 grams, Fructus Rosae Laevigatae 15 grams, Radix Trichosanthis 30 grams, Cortex Phellodendri 20 grams, Poria 30 grams, Herba Dendrobii 15 grams, Rhizoma Polygonati Odorati 15 grams, Semen Plantaginis 15 grams, Herba Lysimachiae 20 grams, Talcum 30 grams, Rhizoma Alismatis 20 grams, Radix Et Rhizoma Rhei 30 grams, Fructus Schisandrae Chinensis 20 grams, Semen Myristicae 15 grams.

Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.

The preparation of [embodiment 4] pill

Each raw material of above-mentioned weight is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.

The preparation of [embodiment 5] oral liquid

Each raw material of above-mentioned weight is mixed, after decocting for three times, three filtrates is mixed, filter, be concentrated into the concentration of regulation, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.

[experimental example] traditional Chinese medicine composition for treating kidney failure diseases of the present invention patient's clinical observation on the therapeutic effect experiment

One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to control 365 routine patients altogether, wherein male 279 examples, women 86 examples; The oldest person 71 years old, the age reckling has only 9 years old.

Therapeutic Method:

Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2～5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.

The course of treatment: one month is a course of treatment, treats for 9 courses of treatment altogether.

The therapeutic evaluation standard

Cure: the edema of the face, edema of the limbs complete obiteration, diet is normal, and spirit is good, and urine retention, creatinine, the every index of albuminuria are normal fully.Check after half a year that index keeps normal, sign is improved fully, and the patient does not have any bad sensation.

Produce effects: the edema of the face, edema of the limbs disappear substantially, and diet is normal, and spirit is good, and urine retention, creatinine, the every index of albuminuria are near normal.

Effectively: the edema of the face, edema of the limbs are improved, and diet is normal, and spirit is good, and urine retention, creatinine, the every index of albuminuria all have in various degree to be improved.

Invalid: sign does not have any change, symptom such as preceding, and every index no change or nothing obviously change.

Model case:

1, what certain, woman, 15 years old.

Before 6 days, trike flu, clothes APC2 sheet is treated, the very night, cold symptoms did not only alleviate, and was heavy all the better, and the edema oliguria occurred, do not arouse attention, obey the APC2 sheet again, 2 of sulfamethoxyplridazine are treated, after tens minutes, the state of an illness is more serious, suddenly send to hospital, adopt the several different methods symptomatic treatment, all do not have positive effect, the state of an illness increases the weight of, haematemesis, hemoptysis, epistaxis, bleeding from the gum, have blood in stool, hematuria, otorrhagia, metrorrhagia, treating serious edema caused, the oliguria urine retention, whole body is seen large stretch of purpura, dysphoria, fever of the body such as charcoal, deep red tongue, slippery and rapid pulse.Take Chinese medicine composition of the present invention after 2 days, begin to bring down a fever, symptom is effectively controlled, continuous clothes Chinese medicine composition of the present invention is brought down a fever after 7 days, and edema is significantly improved; urine is tending towards normal; various symptoms are all significantly alleviated, and take Chinese medicine composition of the present invention again and fully recover after 2 months, and various symptoms all disappear.

2, fiber crops certain, man, 14 years old.

Before 2 months, catch sight of edema, hospitalization, earlier lose improvement with western medicine 1 wheat harvesting period, continue and cooperate day surplus the Chinese medicine 20, the state of an illness is more serious, the height edema, two can not sleeping with eyes half-closed because of edema, enlarged abdomen such as drum, drip urine completely without, hyperpyrexia (40.1 ℃), dysphoria, frequent nausea and vomiting, breathing is the devil, and lip, buccal, finger are all purple dim, pale tongue is dim, the tongue fur HUANGBAI(sic), and the floating and tense pulse number is short puckery.Take Chinese medicine composition of the present invention after 5 days, hyperpyrexia is decorporated substantially, and the urine amount is few, and edema is alleviated, continuous clothes Chinese medicine composition of the present invention is after 7 days, heating disappears, and edema is greatly alleviated, and it is normal that urine is recovered, uncomfortable symptom is greatly taken on a new look, took Chinese medicine composition of the present invention again 1 month, the every index full recovery of health is normal, returns to one's perfect health.

3, Zhang, woman, 67 years old, retired cadre.

Before 2 wheat harvesting periods, dizzy feeling of fullness in the head appears suddenly, vexed cardiopalmus, nausea and vomiting, it is very poor that food is received, hyperpyrexia (39.5 ℃), cough with asthma, must not put down for sleeping in, edema oliguria, enlarged abdomen such as drum, again and again nausea and vomiting, the lip purple is dim, shallow complexion and swelling, the bitter taste xerostomia, desire drink unable to drink refers to that toe faints cold, vexed insomnia, tongue fur HUANGBAI(sic) and being bored with, the short number of floating and tense pulse.All invalid behind the western medicines in treatment, the state of an illness increases the weight of.Take Chinese medicine composition of the present invention after 3 days, bring down a fever gradually, edema is significantly improved, and continuous clothes Chinese medicine composition of the present invention is after 7 days, heating disappears; urine recovers normal, and edema disappears substantially, takes 1 first quarter moon of Chinese medicine composition of the present invention again; various symptoms all disappear; taking patent drug after treatment of the present invention after 3 months, return to one's perfect health, every index is all within normal range.

4, Ma, man, 63 years old, retired employees.

Have a liver complaint for many years, over the past two years, under the difficulty in urination, need take diuretic, can urinate, but urine is clear; Do not take medicine, then dysuria.Gradually to anasarca, the clothes diuretic still drop not down, patient's dim complexion, anasarca, trick more so, even shoes also can't be put on.Light red tongue is fat, and there is petechia on the limit, the greasy fur ash, and the sublingual vein stasis of blood rises, and lower lip is livid purple; Floating pulse is got nothing, in get sliding slightly tightly, refetch sliding big strong.Take Chinese medicine composition of the present invention after 7 days, can withdraw diuretic, the urine amount is few, and edema is alleviated to some extent, continuous clothes Chinese medicine composition of the present invention is after 10 days, and symptom is clearly better, and patient's edema almost all disappears, continuous clothes Chinese medicine composition of the present invention is surplus March, thoroughly rehabilitation, not recurrence so far.

5, together certain, woman, 40 years old, engineer.

Began before 3 years to occur feeling sick, vomitting, the anorexia symptom is felt nocturia simultaneously, do not paid attention to, by " gastropathy " treatment one wheat harvesting period, symptom does not alleviate always, prominent sense was nervous, uncomfortable in chest when the patient went to work before one month, breathe hard, examination in hospital is serum creatinine at that time: 976.35 μ mol/L, blood urea nitrogen: 36.34mmol/L, color ultrasound is shown that two excess of the kidney matter are and is filled the air infringement and change, the anemia looks, eyes face edema, two lower limb Mild edema.Take Chinese medicine composition of the present invention after 15 days, edema is significantly alleviated, and the nocturia number of times reduces, continuous clothes Chinese medicine composition of the present invention is after 20 days, and edema disappears substantially, serum creatinine: 300.14 μ mol/L, blood urea nitrogen: 20.35mmol/L, symptom is significantly improved, and obeys Chinese medicine composition of the present invention again after 2 months, edema disappears, appetite is normal, serum creatinine: 150.27 μ mol/L, blood urea nitrogen: 10.73mmol/L, it is surplus March to take Chinese medicine composition of the present invention again, all transference cures.

6, hot certain, man, 37 years old, teacher.

Suffered from chronic nephritis during prescription on individual diagnosis 3 years, chronic renal failure 1 year, the soreness of waist at that time, weak, feel sick few food, often suffer from diarrhoea skin pruritus, laboratory examination hematochrome 70g/L, serum creatinine 762 μ mol/L, blood urea nitrogen 70.2 μ mol/L through how tame hospital diagnosis, are renal failure, the suggestion dialysis treatment is waited for renal transplantation.Take Chinese medicine composition of the present invention after 15 days, various symptoms are significantly improved, and continuous clothes Chinese medicine composition of the present invention is after 1 month, laboratory examination hematochrome 20g/L, serum creatinine 535 μ mol/L, blood urea nitrogen 48.7 μ mol/L, continuous clothes Chinese medicine composition of the present invention is after 2 months, laboratory examination hematochrome 100mg/L once more, serum creatinine 279 μ mol/L, blood urea nitrogen 26.3 μ mol/L, symptom is greatly taken on a new look, it is surplus March to take Chinese medicine composition of the present invention again, all transference cures.

7, Liu, man, 45 years old, workman.

Face and edema of lower limbs appear in patient's unknown cause before 3 years, the conventional albumen 2+ that has urine examined at that time, serum creatinine: 368umol/L, blood urea nitrogen: 16.8mmol/L.Through how tame hospital therapy, it is invalid to take Chinese and western drugs, spend 30,000 surplus yuan, but the state of an illness continues to increase the weight of.Patient's edema increases the weight of over nearly one month, hypourocrinia, and symptoms such as nausea and vomiting appear, provincial hospital tells the patient will earn a bare living or renal transplantation by dialysis following half a lifetime.Took Chinese medicine composition of the present invention 10 days, edema alleviates, and the state of an illness is effectively controlled, continuous clothes Chinese medicine composition of the present invention 15 days, hydrouria, edema is significantly alleviated, continuous clothes Chinese medicine composition of the present invention is after 1 month, have urine examined conventional albumen+, serum creatinine: 212umol/L, blood urea nitrogen: 9.5mmol/L, it is surplus March to take Chinese medicine composition of the present invention again, stable disease, the patient is energetic, can participate in general physical work.

8, Tang, man, 34 years old, accounting.

In the time of the beginning of this year, he did not take notice of at that time with regard to the intermittent headache that occurs that keeping in mind may be not have a rest, or other reasons.Being dragged to May always, having occurred headache once more, arrived examination in hospital subsequently, is renal damage, and creatinine has reached 680umol/l, and spirit is general, poor appetite, and the whole body is weak, and complexion is gloomy, lumbago, idol has nauseating.Take Chinese medicine composition of the present invention after 15 days, headache is alleviated to some extent, and continuous clothes Chinese medicine composition of the present invention is after 1 month, symptom is greatly taken on a new look, and checks creatinine 360umol/L, and it is surplus April to take Chinese medicine composition of the present invention again, symptom all disappears, and the patient is energetic, and is energetic.

Five, therapeutic outcome:

In the 365 routine cases of being accepted for medical treatment,, wherein cure 261 examples through treatment in 9 months, produce effects 28 examples, effective 57 examples, invalid 19 examples, total effective rate reaches 94%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment kidney failure diseases patient.

Claims

1. Chinese medicine composition for the treatment of kidney failure diseases is characterized in that: mainly contain following bulk drugs and form:

2. according to the described Chinese medicine composition of claim 1, it is characterized in that: the weight portion of each crude drug is:

3. according to the described Chinese medicine composition of claim 1, wherein crude drug also has:

4. according to the described Chinese medicine composition of claim 3, wherein the weight portion of each component is:

5. according to claim 1,2,3 or 4 described any Chinese medicine compositions, it is characterized in that: can be prepared into any oral formulations commonly used according to the method for Chinese medicinal of routine.

6. according to the described Chinese medicine composition of claim 5, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.

7. the application of the described any Chinese medicine composition of claim 1～6 in preparation treatment kidney failure diseases medicine.