CN101785681A - Quantitative measuring and analyzing system for development condition of baby skull - Google Patents
Quantitative measuring and analyzing system for development condition of baby skull Download PDFInfo
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- CN101785681A CN101785681A CN201010033768A CN201010033768A CN101785681A CN 101785681 A CN101785681 A CN 101785681A CN 201010033768 A CN201010033768 A CN 201010033768A CN 201010033768 A CN201010033768 A CN 201010033768A CN 101785681 A CN101785681 A CN 101785681A
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Abstract
The invention provides a quantitative measuring and analyzing system for the development condition of a baby skull. The quantitative measuring and analyzing system comprises an ultrasonic probe, an ultrasonic signal processing part, an electromagnetic positioning device, and an analysis processing and displaying part. The ultrasonic probe is used for emitting ultrasonic waves and receiving return signals of the ultrasonic waves, the ultrasonic signal processing part is used for processing the ultrasonic return signals received by the ultrasonic probe, the electromagnetic positioning device is used for monitoring the position of the ultrasonic probe in real time and outputting a coordinate value, and the analysis processing and displaying part is used for carrying out analysis processing on collected data and displaying the measured skull in a visualized manner. The quantitative measuring and analyzing system not only can quantitatively measure parameters of the baby skull including bone density, bone thickness, radial line of the skull, sutura bondary, fontanel area and the like, but also can display the shape and structural characteristics of the skull in a visualized manner, thereby providing evaluation basis for the development condition of the baby skull.
Description
Technical field
The present invention relates to ultrasonic diagnosis and medical instruments field, more particularly relate to a kind of by ultrasonic quantitative measurement and the system that analyzes development condition of baby skull.
Background technology
Mother's phenolics is calcareous can to cause the dysplasia of neonatal skull sutura with deficiency irony, and the malnutrition of age of sucking can have a strong impact on neonatal skull normal growth and intelligence development.The baby is very fast to the one year old speed of growth from being born, and balanced growth within postnatal a year can reach 12 centimetres as head circumference.The cradle bone growth and development needs enough vitamin D and calcium, replenishes as untimely, and " cephalus quadratus " deformity, i.e. craniotabes disease appear in the fontanel that is positioned at the crown closure that can delay after birth.The ossific process of the closure reflection skull of bregma and sutura, the closed microcephaly that forms easily too early, closure is more common in rickets, hydrocephalus or cretinism etc. too late.Therefore monitoring baby's skull development condition has crucial meaning to its healthy growth in real time.But at present clinical skull development condition to the baby just comes subjective judgment by observation and touch, does not have quantitative methods to carry out objective measurement and analysis.
Summary of the invention
Can't quantitative measurement and the problem of analysis in order to overcome present development condition of baby skull, development condition of baby skull quantitative measurement of the present invention and analytical system are applied to ultrasonic technique and electromagnetic location technology the baby skull measurement and analyze, because the radiationless damage of ultrasound wave, so the present invention can be used safely in baby's skull measurement.
According to an aspect of the present invention, provide a kind of development condition of baby skull quantitative measurement and analytical system, it is characterized in that comprising:
A ultrasonic probe is used to launch ultrasound wave and receives described hyperacoustic echo-signal;
A ultrasonic signal processing section is used for the described ultrasound echo signal that described ultrasonic probe receives is handled;
An electromagnetic location device is used for monitoring in real time the position of described ultrasonic probe and output coordinate value;
Analyzing and processing and display part are used for the data of gathering are carried out Treatment Analysis, and provide visualization display to skull shape and the architectural feature of being surveyed.
Development condition of baby skull quantitative measurement of the present invention and analytical system can realize fetal skull density, bone thickness, skull radial line, sutura border, the isoparametric quantitative measurement of fontanel area, and visualization display is provided and analyzes conclusion automatically, and production cost is low, simple to operate, safe.
The present invention includes supersonic detection device, electromagnetic location device, signal processing circuit, data-interface and analyzing and processing and the display part part of grading.
Described supersonic detection device comprises ultrasonic probe, ultrasonic signal treatment circuit, and ultrasonic probe is a collection ultrasonic emitting and the handheld probe that is received as one, is used to measure bone density, the bone thickness at skull to be measured position, and surveys sutura and fontanel border.The ultrasound echo signal that probe receives is handled analyzing and processing and the display part that also finally is transferred in the computer through signal processing circuit.
During measurement, ultrasonic probe is pressed detected part, adopt the quantitative ultrasound method to calculate the bone density and the thickness of tested point.Ultrasonic signal passes skull, and scattering and absorption take place when organizing, and cause acoustic energy to reduce amplitude step-down, promptly wide wave attenuation.Decay was different when ultrasonic signal was propagated in different medium, and velocity of sound difference at the critical surface of different medium obvious reflection can take place.By measuring wide wave attenuation value, SVEL and reflection echo, density, thickness, microstructure and other parameter attributes of osseous tissue can be described out.Because the intensity of bone is by the decision of factors such as bone density and bone micro-structure, therefore by the quantitative ultrasound method just can the composite measurement bone intensity.Because sutura and fontanel are soft tissue, Ultrasonic attenuation significantly diminishes, and therefore can change the border of determining sutura and fontanel according to the amplitude of ultrasonic echo, and then depict the shape of fontanel.With adult different, baby's skull is softer, and not the healing sutura whole skull is divided into several sections, bone density and the bone one-tenth-value thickness 1/10 of skull on different parts, different directions also has evident difference.Therefore ultrasonic probe need be measured several parts such as occipital bone, parietal bone, frontal bone respectively, and measures the center and peripheral position of each several part bone respectively, obtains comprehensive data.
Described positioner adopts the electromagnetic location device, paste a witness marker point in ultrasonic probe one side, catch the coordinate of discerning witness marker point by the electromagnetic location device, calculate the position of ultrasonic probe, and then be used to calculate skull footpath line length, fontanel area etc.The electromagnetic location device produces stable magnetic field, by demarcating is a three-dimensional system of coordinate, index point is a magnet-sensitive element, by electromagnetic induction can recognition marks point D coordinates value, realization is to the location of ultrasonic probe, analyzing and processing and display part can the real time record index point coordinate figure, and the displacement of the coordinate Calculation ultrasonic probe by tracking mark point.The radial line of skull is an important indicator of judging head shapes, mainly comprises biparietal diameter, suboccipitobregmatic diameter, occipitofrontal diameter, lower jaw calvarium footpath etc., can depict the shape of skull by these several main radial lines.Ultrasonic probe is surveyed the initial sum final position of these several radial lines respectively, obtains the starting point and the terminal point coordinate of radial line by the index point location, and then calculates the footpath line length.The coordinate figure of witness marker point can be used to calculate the position of sutura and the area of fontanel when extracting ultrasonic probe measurement sutura and fontanel border.
Described analyzing and processing and display part comprise data record unit, data computation unit and a virtual standard baby skull model, and wherein data record unit is used for the ultrasonic signal parameter of the described ultrasonic signal of real time record processing section transmission and the coordinate figure of described witness marker point; The data computation unit is used for calculating bone density, bone thickness etc. according to ultrasound echo signal, calculates parameters such as skull radial line, fontanel area according to described witness marker point coordinates value; Virtual standard baby skull model comprises skull, sutura, fontanel, goes up mandibular bone and skull bottom, give material properties such as the certain bone density of skull model each several part, thickness according to the clinical experiment data respectively, be used for visualization display baby skull shape and architectural feature.The parameter of described virtual standard baby skull model is provided with part and links to each other with the unitary data output of described data computation, this model parameter can realize revising automatically according to measured data, skull radial line, sutura position and the fontanel shape etc. that record according to ultrasonic probe and positioner, can revise the standard header bone model, the shape of true reappearance actual measurement skull; According to parameters such as the bone density that records, bone thickness its material properties is reseted, embodied the architectural feature of skull.Parameter default under actual measurement parameter and corresponding age is compared normal range, can make the analysis conclusion the development condition of actual measurement baby skull.The record Measuring Time is used for the comparison of different period measurement results, can satisfy clinical research needs to the baby skull growth course.
This device can be by the quantitative assay baby parameter and normal value contrasts such as skull density, thickness, skull radial line, thereby judge whether it exists the symptom of calcium deficiency; In conjunction with the ankylose situation of sutura and fontanel, skull development condition that can the analysis-by-synthesis baby.The data that this device is surveyed also can be used for clinical in to the research of baby skull growth course, and provide data information for the baby skull modeling in the scientific research.
The advantage of development condition of baby skull quantitative measurement of the present invention and analytical system comprises:
1, can measure parameters such as comprising bone density, bone thickness, skull radial line, sutura border, fontanel area comprehensively;
2, can write down the parameter normal range that measurement data and contrast are preset automatically, baby's skull development condition is made analysis-by-synthesis;
3, can visualization display skull shape and architectural feature, be used for clinical and scientific research;
4, certainty of measurement height, operating process is easy, radiationless damage.
Description of drawings
Fig. 1 is the population structure sketch map of development condition of baby skull quantitative measurement according to an embodiment of the invention and analytical system;
Fig. 2 example has shown a Visualization Model that can be used in system shown in Figure 1 analyzing and processing and the display part.
The specific embodiment
As shown in Figure 1, be development condition of baby skull quantitative measurement according to an embodiment of the invention and analytical system, comprise ultrasonic probe 1, ultrasonic signal processing section 105, data-interface 106, electromagnetic location device 107, analyzing and processing and display part 4.Wherein be pasted with a witness marker point 2 on the ultrasonic probe 1.Analyzing and processing and display part 4 comprise data record unit, data computation unit and the revisable standard baby skull of a parameter model.
According to one embodiment of present invention, ultrasonic probe 1 as shown in Figure 1 is a collection ultrasonic emitting and is received as the handheld probe of one, is used to measure baby to be measured 3 bone density, bone thickness, and the border of the position of definite sutura 6 and fontanel 5.
According to a kind of concrete metering system, ultrasonic probe 1 is pressed baby 3 detected part, ultrasonic signal reflects when passing skull and interior tissue, scattering and absorption, causes acoustic energy to reduce the amplitude step-down.The ultrasound echo signal that ultrasonic probe 1 receives reaches ultrasonic signal processing section 105, through analyzing and processing and the display part 4 of data-interface 106 repeated transmission to the computer, thereby can handle, write down and show parameters such as ultransonic wide wave attenuation, SVEL, propagation time, echo amplitude.Wide wave attenuation is defined as wide wave attenuation value to the slope of frequency, can reflect the parameters,acoustic of osseous tissue, is used to describe bone density.The echo of ultrasonic signal can produce obvious mutation at the interface of osseous tissue and soft tissue, can be according to propagation time and the long-pending thickness that calculates bone of the velocity of sound.Because fontanel 5 is the less soft tissues of relative osseous tissue density with sutura 6 places, attenuation change was bigger when ultrasonic probe 1 scanning was passed through, bigger variation also takes place in the amplitude of reflection echo, can change separation according to the amplitude of ultrasonic echo in view of the above and determine the border of fontanel 5 and sutura 6, and then depict the shape of fontanel 5.Therefore, by measuring wide wave attenuation value, SVEL and reflection echo, density, thickness, bone micro-structure, sutura position, fontanel border and other parameter attributes of osseous tissue can be described out.Because the intensity of bone by the decision of factors such as bone density and bone micro-structure, therefore just can be measured the intensity of bone by the quantitative ultrasound method.With adult different, baby's skull is softer, and not the healing sutura whole skull is divided into several sections, bone density and the bone one-tenth-value thickness 1/10 of skull on different parts, different directions also has evident difference.Therefore ultrasonic probe 1 needs several parts such as scanning survey occipital bone, parietal bone, frontal bone, and measures the center and peripheral position of each several part bone respectively, obtains comprehensive data.
According to one embodiment of present invention, electromagnetic location device 107 as shown in Figure 1 adopts the electromagnetic location principle, is used to follow the tracks of the position of determining ultrasonic probe 1, and then is used to calculate skull radial line, sutura border, fontanel area etc.
According to one embodiment of present invention, electromagnetic location device 107 can produce a stabilizing magnetic field, and this magnetic field is demarcated in a three-dimensional system of coordinate.Be pasted with a witness marker point 2 on ultrasonic probe 1, index point 2 is a magnetic sensing element, can change the external magnetic field.The D coordinates value of index point 2 can be determined in the position of detecting changes of magnetic field by electromagnetic location device 107, and then the position of definite ultrasonic probe 1, is used for the definite of the calculating of skull radial line and fontanel 5, sutura 6 boundary position points.The radial line of skull is an important indicator of judging head shapes, and comprise following several main radial lines: biparietal diameter refers to the distance between the parietal bone knuckle of both sides; Suboccipitobregmatic diameter refers to the distance of bregma central authorities to the occipital protuberance below; Occipitofrontal diameter also claims anteroposterior diameter, refers to from the nasion to the distance between occipital protuberance; Lower jaw calvarium footpath refers to chin bone bottom center to the distance between the posterior top, and the lower jaw calvarium directly is the maximum radial line of fetal head.Ultrasonic probe 1 is placed on the starting point and the final position of these several radial lines respectively, obtains the starting point and the terminal point coordinate of several radial lines of tested skull by the index point on the ultrasonic probe 12 being caught the location, and then calculate the footpath line length.The coordinate figure of witness marker point can be used to calculate the width of sutura and the area of fontanel when extracting ultrasonic probe measurement sutura and fontanel boundary point.
According to one embodiment of present invention, analyzing and processing as shown in Figure 2 and display part 4 comprise data record unit, data computation unit and a standard baby skull model, be used for record, calculating data, according to the parameter that calculates skull model is carried out parameter modification, thereby the shape and the architectural feature of baby skull that visualization display is surveyed, and, make the analysis conclusion by surveying the contrast of parameter and default normal range.According to one embodiment of present invention, baby skull model in analyzing and processing and the display part 4 is obtained through 3-D scanning by standard baby skull mock-up, form by skull, fontanel 5, sutura 6, last mandibular bone and skull bottom, give material properties such as the certain bone density of each several part, thickness according to the clinical experiment data.According to skull radial line, fontanel 5 borders and the sutura 6 location point coordinates that ultrasonic probe 1 and electromagnetic location device 107 record, can revise the parameter value of skull model in analyzing and processing and the display part 4, the shape of true reappearance actual measurement skull; According to parameters such as the bone density that records, bone thickness its material properties is reseted, indicated different bone densities, show the architectural feature of institute's gauge head bone by color.According to a specific embodiment, Measuring Time can be used for the not comparison of same date measurement result by analyzing and processing and display part 4 automatic records, satisfies clinical research demand to the baby skull growth course.
According to one embodiment of present invention, the output of the data of ultrasonic signal processing section 105 and electromagnetic location device 107 is sent to the analyzing and processing in the computer and the data record unit of display part 4 by data-interface 106, calculate desired parameters through the data computation unit again, the unitary output of data computation is provided with part with the parameter of baby skull model and is connected, and realizes that the parameter of baby skull model is revised automatically.Age bracket according to the baby is divided, each parameter is preset with normal range in the baby skull model, according to the contrast of measured parameter value and default normal range, analyzing and processing and display part 4 can be made the analysis conclusion automatically, as the evaluation foundation to the actual measurement development condition of baby skull.
Embodiment quantitative measurement and analysis development condition of baby skull
Open the switch of Ultrasound Instrument and electromagnetic location device 107, press baby head 3 after ultrasonic probe 1 smeared couplant, along the starting point of occipitofrontal diameter 7 and terminal point line (promptly from the nasion between occipital protuberance) scanning, pass through the fontanel 5 and the sutura 6 of frontal bone, parietal bone and occipital bone and intermediate formation thereof respectively.Ultrasonic probe 1 ultrasonic waves transmitted is received by probe 1 behind osseous tissue and soft tissue reflection loss again, carries out computational analysis through analyzing and processing and display part 4 that the signal processing circuit part 105 and the data-interface 106 of Ultrasound Instrument is sent in the computer.
Ultrasonic probe 1 detects parameters such as wide wave attenuation in the ultrasound echo signal, SVEL, propagation time, echo amplitude.The bone density of skull is described according to wide wave attenuation value; The long-pending bone thickness of describing skull according to the propagation time and the velocity of sound; The witness marker that amplitude changes and electromagnetic location device 107 captures according to ultrasonic echo is put the boundary position that 2 coordinate figures are judged fontanel 5 and sutura 6, and calculates the fontanel area; Put the length that 2 coordinate figures calculate occipitofrontal diameter 7 according to the witness marker of ultrasonic probe when the starting point of occipitofrontal diameter 7 and the terminal point.
Measure other radial line and skull position according to above-mentioned same method, obtain comprehensive data.
The data that supersonic detection device and electromagnetic location device 107 record are by analyzing and processing and display part 4 records and calculate parameters such as bone density, bone thickness, skull footpath line length, fontanel 5 and sutura 6 borders, the parameter that result of calculation is connected to virtual skull model is provided with part, realize the automatic modification of skull model parameter value, can truly describe the shape and the architectural feature of tested baby skull, and realize the demonstration of tested baby skull model in visible.The input infant age, by bone density, bone thickness, directly ankylose situation and this age corresponding preset contrast normal range of line length, fontanel 5 and sutura 6 of skull of actual measurement, the analysis conclusion is finally made to the development condition of tested baby skull in analyzing and processing and display part 4.The date measured in record, can be used for the comparison of different period measurement results, and satisfy clinical research demand to the baby skull growth course.
Should be understood that, in above narration and explanation to just explanation but not determinate of description that the present invention carried out, and do not breaking away under the prerequisite of the present invention that limits as appended claims, can carry out various changes, distortion and/or correction the foregoing description.
The drawing reference numeral explanation
1, ultrasonic probe 2, position mark point 3, baby head 4, analyzing and processing and display part
5, fontanel 6, sutura 7, occipitofrontal diameter 105, ultrasonic signal processing section
106, data-interface 107, electromagnetic location device
Claims (6)
1. development condition of baby skull quantitative measurement and analytical system is characterized in that comprising:
A ultrasonic probe (1) is used to launch ultrasound wave and receives described hyperacoustic echo-signal;
A ultrasonic signal processing section (105) is used for the described ultrasound echo signal that described ultrasonic probe (1) receives is handled;
An electromagnetic location device (107) is used for monitoring in real time the position of described ultrasonic probe (1) and output coordinate value;
Analyzing and processing and display part (4) are used for the ultrasonic and locator data of gathering is carried out Treatment Analysis, and provide visualization display to skull shape and the architectural feature of being surveyed.
2. device according to claim 1 is characterized in that:
Be pasted with a witness marker point (2) on the described ultrasonic probe (1),
Wherein said electromagnetic location device (107) can produce a stable magnetic field, and this magnetic field is demarcated in a three-dimensional system of coordinate,
Described electromagnetic location device (107) can utilize described three-dimensional system of coordinate to discern the spatial value of described witness marker point (2), thereby determines the position of described ultrasonic probe.
3. device according to claim 1 is characterized in that described analyzing and processing and display part (4) comprising:
A data record cell is used for the ultrasonic signal parameter of the described ultrasonic signal of real time record processing section (105) transmission and the coordinate figure of described witness marker point (2),
A data computation unit is used to calculate parameters such as bone density, bone thickness, skull radial line, fontanel area,
A virtual standard baby skull model, this baby skull model comprise skull, sutura and fontanel, go up mandibular bone and skull bottom, are used for the tested baby's of visualization display skull shape and architectural feature.
4. device according to claim 3 is characterized in that:
The parameter of described virtual standard baby skull model is provided with part and links to each other with the unitary data output of described data computation, and this model parameter can realize revising automatically according to measured data, and contrast is made the analysis conclusion after presetting normal range.
5. device according to claim 1 is characterized in that further comprising:
Data-interface (106) is used to realize the data communication of described signal processing (105) and described electromagnetic location device (107) and analyzing and processing and display part (4).
6. device according to claim 1 is characterized in that:
Described witness marker point (2) is a magnetic sensing element, can change the magnetic field at its place, position,
Described electromagnetic location device (107) is used for determining the three-dimensional coordinate of described witness marker point (2) at described three-dimensional system of coordinate by the variation that detects described magnetic field, and then determines the position of described ultrasonic probe (1).
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| CN2010100337680A CN101785681B (en) | 2010-01-13 | 2010-01-13 | Quantitative measuring and analyzing system for development condition of baby skull |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417243A (en) * | 2012-05-24 | 2013-12-04 | 中慧医学成像有限公司 | Three-dimensional ultrasonic imaging device, three-dimensional ultrasonic imaging system and three-dimensional ultrasonic imaging method |
| CN108186023A (en) * | 2017-12-28 | 2018-06-22 | 深圳开立生物医疗科技股份有限公司 | The method of automatic measurement IFA |
| CN110811691A (en) * | 2014-03-20 | 2020-02-21 | 深圳迈瑞生物医疗电子股份有限公司 | Method and device for automatically identifying measurement items and ultrasonic imaging equipment |
| CN116196038A (en) * | 2023-04-28 | 2023-06-02 | 南京澳思泰生物科技有限公司 | Ultrasonic multi-mode image fusion bone mineral density measurement system and method |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100469321C (en) * | 2005-11-28 | 2009-03-18 | 香港理工大学 | Three-dimensional ultrasonic detection method |
| CN101396284A (en) * | 2008-10-07 | 2009-04-01 | 深圳市蓝韵实业有限公司 | Method for quickly judging whether the embryo growth and development is normal or not |
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2010
- 2010-01-13 CN CN2010100337680A patent/CN101785681B/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417243A (en) * | 2012-05-24 | 2013-12-04 | 中慧医学成像有限公司 | Three-dimensional ultrasonic imaging device, three-dimensional ultrasonic imaging system and three-dimensional ultrasonic imaging method |
| CN110811691A (en) * | 2014-03-20 | 2020-02-21 | 深圳迈瑞生物医疗电子股份有限公司 | Method and device for automatically identifying measurement items and ultrasonic imaging equipment |
| US11717183B2 (en) | 2014-03-20 | 2023-08-08 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Method and device for automatic identification of measurement item and ultrasound imaging apparatus |
| CN108186023A (en) * | 2017-12-28 | 2018-06-22 | 深圳开立生物医疗科技股份有限公司 | The method of automatic measurement IFA |
| CN116196038A (en) * | 2023-04-28 | 2023-06-02 | 南京澳思泰生物科技有限公司 | Ultrasonic multi-mode image fusion bone mineral density measurement system and method |
| CN116196038B (en) * | 2023-04-28 | 2023-07-28 | 南京澳思泰生物科技有限公司 | Ultrasonic multi-mode image fusion bone mineral density measurement system and method |
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| CN101785681B (en) | 2012-06-20 |
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