CN101757572B - Traditional Chinese medicine composition for treating infantile cerebral palsy and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating infantile cerebral palsy and preparation method thereof Download PDFInfo
- Publication number
- CN101757572B CN101757572B CN2010103004434A CN201010300443A CN101757572B CN 101757572 B CN101757572 B CN 101757572B CN 2010103004434 A CN2010103004434 A CN 2010103004434A CN 201010300443 A CN201010300443 A CN 201010300443A CN 101757572 B CN101757572 B CN 101757572B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- rhizoma
- chinese medicine
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a new traditional Chinese medicine composition for treating infantile cerebral palsy and a preparation method thereof. The traditional Chinese medicine composite is mainly prepared from the following raw materials of codonopsis pilosula, unprepared astragalus mongholicus, white paeony root, fructus alpiniae oxyphyllae, notopterygium root, radix angelicae, kudzu vine root, chrysanthemum, prepared rehmannia root, red-rooted salvia root, medicated leaven, Ligusticum wallichii, dalbergia wood, trichosanthes kirilowii Maxim, storax, rhizoma acori graminei, Chinese angelica,polygonum multiflorum, rhizoma sparganii, curcuma zedoary, cyperus rotundus, radix curcumae, cherokee rose fruit, plantain seed, leonurus, peach kernel, red flower, red-rooted salvia root, elecampaneand the like. The traditional Chinese medicine composition can be made into any kind of common orally taken preparation by using conventional traditional Chinese medicine preparation methods. The traditional Chinese medicine composition can obviously improve muscle and bone weekness, bradygenesis, muscle flaccidity, head and neck enervation, mental incapacity, dull expression, sound delay, salivation, poor appetite, loose stool, slow response, logagnosia, dementia and other symptoms and achieve definite, obvious and quick treatment effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of cerebral palsy of children.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment cerebral palsy of children of crude drug with the Chinese herbal medicine.
Background technology
Cerebral palsy of children is the brain material injury that causes owing to multiple reasons such as children's infects, hemorrhage, wounds, non-carrying out property, kentrokiness dysfunction occur and develops into the disease of paralysis.Clinical manifestation: kentrokiness obstacle, muscular tension and abnormal posture etc., severe patient are with mental deficiency, performances such as epilepsy, limbs tic and vision, audition, language function obstacle, and the clinical onset rate has the trend of continuous rising in recent years.
Modern medicine often falls flat at clinical a certain symptom treatment, can not find suitable Therapeutic Method, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines, treating both the principal and secondary aspects of a disease of Chinese traditional treatment cerebral palsy of children, deficiency and excess is also controlled, inside and outside logical the accent, emergency is taken in concurrently, filters out nourishing the liver and kidney, bone and muscle strengthening, the stasis of blood of living are reduced phlegm, the natural plant that collateral dredging is had one's ideas straightened out according to the theory of Chinese medical science prescription, is prepared from according to certain weight proportion.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment cerebral palsy of children that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment cerebral palsy of children of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of cerebral palsy of children of the present invention, the component of main following weight portion is formed:
1～100 part of Radix Codonopsis, 1～300 part of Radix Astragali, 1～50 part of Radix Ginseng, 1～50 part of Radix Panacis Quinquefolii, 1～100 part of the Radix Paeoniae Alba, 1～150 part of Fructus Alpiniae Oxyphyllae, 1～100 part of Radix Achyranthis Bidentatae, 1～150 part of Rhizoma Dioscoreae, 1～150 part of Fructus Lycii, 1～100 part of Rhizoma Et Radix Notopterygii, 1～100 part of the Radix Angelicae Dahuricae, 1～50 part of Herba Menthae, 1～300 part of Radix Puerariae, 1～150 part of Flos Chrysanthemi, 1～150 part of Radix Trichosanthis, 1～150 part of Semen Cassiae, 1～150 part of Radix Scutellariae, 1～50 part of Rhizoma Coptidis, 1～150 part of Radix Rehmanniae Preparata, 1～150 part of Radix Salviae Miltiorrhizae, 1～100 part of Radix Notoginseng, 1～100 part of Radix Et Rhizoma Rhei, 1～150 part of Cortex Lycii, 1～100 part of Radix Angelicae Pubescentis, 1～300 part of Massa Medicata Fermentata, 1～100 part of Fructus Evodiae, 1～50 part in Pericarpium Zanthoxyli, 1～300 part of Pericarpium Citri Reticulatae, 1～150 part of Rhizoma Chuanxiong, 1～150 part of Lignum Dalbergiae Odoriferae, 1～300 part of Fructus Trichosanthis, 1～50 part of the Rhizoma Pinelliae, 1～100 part of Styrax, 1～300 part of Rhizoma Acori Graminei, 1～100 part of Radix Angelicae Sinensis, 1～150 part of Radix Polygoni Multiflori, 1～100 part of Fructus Schisandrae Chinensis, 1～100 part of Fructus Tritici Levis, 1～150 part of Semen Euryales, 1～150 part of Radix Ophiopogonis, 1～150 part of Radix Asparagi, 1～150 part of Radix Adenophorae (Radix Glehniae), 1～100 part of rhizoma sparganic, 1～100 part of Rhizoma Curcumae.
Be preferably:
50 parts of Radix Codonopsis, 100 parts of Radix Astragali, 15 parts of Radix Ginsengs, 10 parts of Radix Panacis Quinquefoliis, 60 parts of the Radix Paeoniae Albas, 50 parts of Fructus Alpiniae Oxyphyllae, 30 parts of Radix Achyranthis Bidentataes, 100 parts of Rhizoma Dioscoreaes, 50 parts of Fructus Lycii, 30 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Menthaes, 150 parts of Radix Puerariaes, 30 parts of Flos Chrysanthemis, 50 parts of Radix Trichosanthis, 30 parts of Semen Cassiaes, 50 parts of Radix Scutellariaes, 30 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae Preparata, 30 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Notoginseng, 30 parts of Radix Et Rhizoma Rhei, 50 parts of Cortex Lycii, 30 parts of Radix Angelicae Pubescentiss, 100 parts of Massa Medicata Fermentata, 30 parts of Fructus Evodiaes, 15 parts in Pericarpium Zanthoxyli, 100 parts of Pericarpium Citri Reticulataes, 60 parts of Rhizoma Chuanxiongs, 50 parts of Lignum Dalbergiae Odoriferaes, 100 parts of Fructus Trichosanthis, 20 parts of the Rhizoma Pinelliaes, 30 parts of Styrax, 100 parts of Rhizoma Acori Graminei, 60 parts of Radix Angelicae Sinensis, 100 parts of Radix Polygoni Multiflori, 30 parts of Fructus Schisandrae Chinensis, 30 parts of Fructus Tritici Levis, 100 parts of Semen Euryaless, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 30 parts of Radix Adenophorae (Radix Glehniae), 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
1～300 part of Rhizoma Cyperi, 1～150 part of Radix Curcumae, 1～100 part of Fructus Rosae Laevigatae, 1～100 part of Fructus Ligustri Lucidi, 1～150 part of Herba Dendrobii, 1～150 part of Rhizoma Polygonati Odorati, 1～150 part in Fructus Hordei Germinatus, 1～50 part of Fructus Amomi, 1～150 part of Rhizoma Alismatis, 1～100 part of Semen Plantaginis, 1～150 part of Herba Leonuri, 1～50 part in Semen Persicae, 1～50 part on Flos Carthami, 1～150 part of Radix Salviae Miltiorrhizae, 1～50 part of Sanguis Draxonis, 1～100 part of Squama Manis (processed), 1～150 part of Carapax Trionycis (processed), 1～150 part of Carapax Et Plastrum Testudinis (processed), 1～150 part of Cortex Magnoliae Officinalis, 1～100 part of Radix Peucedani, 1～100 part of Bulbus Fritillariae Uninbracteatae, 1～100 part of Herba Lysimachiae foenum-graeci, 1～150 part of Benzoinum, 1～150 part of the Radix Aucklandiae, 1～150 part of the Radix Linderae, 1～150 part of Fructus Setariae Germinatus.
Be preferably:
150 parts of Rhizoma Cyperi, 100 parts of Radix Curcumaes, 30 parts of Fructus Rosae Laevigatae, 30 parts of Fructus Ligustri Lucidi, 50 parts of Herba Dendrobiis, 50 parts of Rhizoma Polygonati Odorati, 100 parts in Fructus Hordei Germinatus, 30 parts of Fructus Amomis, 50 parts of Rhizoma Alismatis, 40 parts of Semen Plantaginiss, 100 parts of Herba Leonuris, 20 parts in Semen Persicae, 20 parts on Flos Carthami, 50 parts of Radix Salviae Miltiorrhizaes, 10 parts of Sanguis Draxonis, 30 parts of Squama Manis (processed), 100 parts of Carapax Trionycis (processed), 100 parts of Carapax Et Plastrum Testudinis (processed), 50 parts of Cortex Magnoliae Officinalis, 30 parts of Radix Peucedanis, 30 parts of Bulbus Fritillariae Uninbracteataes, 30 parts of Herba Lysimachiae foenum-graeci, 30 parts of Benzoinumes, 50 parts of the Radix Aucklandiae, 50 parts of the Radixs Linderae, 30 parts of Fructus Setariae Germinatuss.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2～5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to the cerebral palsy of children patient is very effective, and various crude drug are coordinated mutually can play together and at utmost brought into play drug effect.Because this disease mainly is by congenital defect, or will lose the day after tomorrow and support, or imbalance after being ill, causing asthenia of essence and blood, brains lose and fill, and the vital organs of the human body, muscles and bones muscle, extremity bones of the body collectively lose supports, and forms the card of loss.Chinese medicine is thought: the brain being the house of mentality, cause mental retardation, bradykinesia, slurred speech, masticatory atonia, the time sialorrhea water, myasthenia of limbs, soft can not the gripping, soft can not the standing of foot.Or experience pyretic toxicity, and damage brain network, later stage consumption impairment of QI the moon, brains and extremity bones of the body collectively, muscles lose supports, and causes primary disease.Chinese medicine composition of the present invention can effectively improve the self-coordination ability of patient's body, significantly improves function and clinical subjective symptoms, has advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: 50 parts of Radix Codonopsis, 100 parts of Radix Astragali, 15 parts of Radix Ginsengs, 10 parts of Radix Panacis Quinquefoliis, 60 parts of the Radix Paeoniae Albas, 50 parts of Fructus Alpiniae Oxyphyllae, 30 parts of Radix Achyranthis Bidentataes, 100 parts of Rhizoma Dioscoreaes, 50 parts of Fructus Lycii, 30 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Menthaes, 150 parts of Radix Puerariaes, 30 parts of Flos Chrysanthemis, 50 parts of Radix Trichosanthis, 30 parts of Semen Cassiaes, 50 parts of Radix Scutellariaes, 30 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae Preparata, 30 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Notoginseng, 30 parts of Radix Et Rhizoma Rhei, 50 parts of Cortex Lycii, 30 parts of Radix Angelicae Pubescentiss, 100 parts of Massa Medicata Fermentata, 100 parts of Pericarpium Citri Reticulataes, 60 parts of Rhizoma Chuanxiongs, 50 parts of Lignum Dalbergiae Odoriferaes, 100 parts of Fructus Trichosanthis, 20 parts of the Rhizoma Pinelliaes, 30 parts of Styrax, 100 parts of Rhizoma Acori Graminei, 60 parts of Radix Angelicae Sinensis, 100 parts of Semen Euryaless, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of rhizoma sparganic, Rhizoma Curcumae 15,150 parts of Rhizoma Cyperi, 100 parts of Radix Curcumaes, 30 parts of Fructus Rosae Laevigatae, 30 parts of Fructus Ligustri Lucidi, 50 parts of Herba Dendrobiis, 50 parts of Rhizoma Polygonati Odorati, 100 parts in Fructus Hordei Germinatus, 50 parts of Rhizoma Alismatis, 40 parts of Semen Plantaginiss, 50 parts of Radix Salviae Miltiorrhizaes, 10 parts of Sanguis Draxonis, 30 parts of Squama Manis (processed), 100 parts of Carapax Trionycis (processed), 100 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Benzoinumes, 50 parts of the Radix Aucklandiae, 50 parts of the Radixs Linderae.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: 50 parts of Radix Codonopsis, 100 parts of Radix Astragali, 15 parts of Radix Ginsengs, 10 parts of Radix Panacis Quinquefoliis, 60 parts of the Radix Paeoniae Albas, 50 parts of Fructus Alpiniae Oxyphyllae, 30 parts of Radix Achyranthis Bidentataes, 100 parts of Rhizoma Dioscoreaes, 50 parts of Fructus Lycii, 30 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Menthaes, 150 parts of Radix Puerariaes, 30 parts of Flos Chrysanthemis, 50 parts of Radix Trichosanthis, 30 parts of Semen Cassiaes, 50 parts of Radix Scutellariaes, 30 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae Preparata, 30 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Notoginseng, 30 parts of Radix Et Rhizoma Rhei, 50 parts of Cortex Lycii, 30 parts of Radix Angelicae Pubescentiss, 100 parts of Massa Medicata Fermentata, 100 parts of Pericarpium Citri Reticulataes, 60 parts of Rhizoma Chuanxiongs, 50 parts of Lignum Dalbergiae Odoriferaes, 100 parts of Fructus Trichosanthis, 20 parts of the Rhizoma Pinelliaes, 30 parts of Styrax, 100 parts of Rhizoma Acori Graminei, 60 parts of Radix Angelicae Sinensis, 100 parts of Semen Euryaless, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of rhizoma sparganic, Rhizoma Curcumae 15,150 parts of Rhizoma Cyperi, 100 parts of Radix Curcumaes, 30 parts of Fructus Rosae Laevigatae, 30 parts of Fructus Ligustri Lucidi, 50 parts of Herba Dendrobiis, 50 parts of Rhizoma Polygonati Odorati, 100 parts in Fructus Hordei Germinatus, 50 parts of Rhizoma Alismatis, 40 parts of Semen Plantaginiss, 50 parts of Radix Salviae Miltiorrhizaes, 10 parts of Sanguis Draxonis, 30 parts of Squama Manis (processed), 100 parts of Carapax Trionycis (processed), 100 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Benzoinumes, 50 parts of the Radix Aucklandiae, 50 parts of the Radixs Linderae.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material according to following weight portion: 50 parts of Radix Codonopsis, 100 parts of Radix Astragali, 15 parts of Radix Ginsengs, 10 parts of Radix Panacis Quinquefoliis, 60 parts of the Radix Paeoniae Albas, 50 parts of Fructus Alpiniae Oxyphyllae, 30 parts of Radix Achyranthis Bidentataes, 100 parts of Rhizoma Dioscoreaes, 50 parts of Fructus Lycii, 30 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Menthaes, 150 parts of Radix Puerariaes, 30 parts of Flos Chrysanthemis, 50 parts of Radix Trichosanthis, 30 parts of Semen Cassiaes, 50 parts of Radix Scutellariaes, 30 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae Preparata, 30 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Notoginseng, 30 parts of Radix Et Rhizoma Rhei, 50 parts of Cortex Lycii, 30 parts of Radix Angelicae Pubescentiss, 100 parts of Massa Medicata Fermentata, 100 parts of Pericarpium Citri Reticulataes, 60 parts of Rhizoma Chuanxiongs, 50 parts of Lignum Dalbergiae Odoriferaes, 100 parts of Fructus Trichosanthis, 20 parts of the Rhizoma Pinelliaes, 30 parts of Styrax, 100 parts of Rhizoma Acori Graminei, 60 parts of Radix Angelicae Sinensis, 100 parts of Semen Euryaless, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of rhizoma sparganic, Rhizoma Curcumae 15,150 parts of Rhizoma Cyperi, 100 parts of Radix Curcumaes, 30 parts of Fructus Rosae Laevigatae, 30 parts of Fructus Ligustri Lucidi, 50 parts of Herba Dendrobiis, 50 parts of Rhizoma Polygonati Odorati, 100 parts in Fructus Hordei Germinatus, 50 parts of Rhizoma Alismatis, 40 parts of Semen Plantaginiss, 50 parts of Radix Salviae Miltiorrhizaes, 10 parts of Sanguis Draxonis, 30 parts of Squama Manis (processed), 100 parts of Carapax Trionycis (processed), 100 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Benzoinumes, 50 parts of the Radix Aucklandiae, 50 parts of the Radixs Linderae.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material according to following weight portion: 50 parts of Radix Codonopsis, 100 parts of Radix Astragali, 15 parts of Radix Ginsengs, 10 parts of Radix Panacis Quinquefoliis, 60 parts of the Radix Paeoniae Albas, 50 parts of Fructus Alpiniae Oxyphyllae, 30 parts of Radix Achyranthis Bidentataes, 100 parts of Rhizoma Dioscoreaes, 50 parts of Fructus Lycii, 30 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Menthaes, 150 parts of Radix Puerariaes, 30 parts of Flos Chrysanthemis, 50 parts of Radix Trichosanthis, 30 parts of Semen Cassiaes, 50 parts of Radix Scutellariaes, 30 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae Preparata, 30 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Notoginseng, 30 parts of Radix Et Rhizoma Rhei, 50 parts of Cortex Lycii, 30 parts of Radix Angelicae Pubescentiss, 100 parts of Massa Medicata Fermentata, 100 parts of Pericarpium Citri Reticulataes, 60 parts of Rhizoma Chuanxiongs, 50 parts of Lignum Dalbergiae Odoriferaes, 100 parts of Fructus Trichosanthis, 20 parts of the Rhizoma Pinelliaes, 30 parts of Styrax, 100 parts of Rhizoma Acori Graminei, 60 parts of Radix Angelicae Sinensis, 100 parts of Semen Euryaless, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of rhizoma sparganic, Rhizoma Curcumae 15,150 parts of Rhizoma Cyperi, 100 parts of Radix Curcumaes, 30 parts of Fructus Rosae Laevigatae, 30 parts of Fructus Ligustri Lucidi, 50 parts of Herba Dendrobiis, 50 parts of Rhizoma Polygonati Odorati, 100 parts in Fructus Hordei Germinatus, 50 parts of Rhizoma Alismatis, 40 parts of Semen Plantaginiss, 50 parts of Radix Salviae Miltiorrhizaes, 10 parts of Sanguis Draxonis, 30 parts of Squama Manis (processed), 100 parts of Carapax Trionycis (processed), 100 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Benzoinumes, 50 parts of the Radix Aucklandiae, 50 parts of the Radixs Linderae.
Each raw material of above-mentioned weight is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material according to following weight portion: 50 parts of Radix Codonopsis, 100 parts of Radix Astragali, 15 parts of Radix Ginsengs, 10 parts of Radix Panacis Quinquefoliis, 60 parts of the Radix Paeoniae Albas, 50 parts of Fructus Alpiniae Oxyphyllae, 30 parts of Radix Achyranthis Bidentataes, 100 parts of Rhizoma Dioscoreaes, 50 parts of Fructus Lycii, 30 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Menthaes, 150 parts of Radix Puerariaes, 30 parts of Flos Chrysanthemis, 50 parts of Radix Trichosanthis, 30 parts of Semen Cassiaes, 50 parts of Radix Scutellariaes, 30 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae Preparata, 30 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Notoginseng, 30 parts of Radix Et Rhizoma Rhei, 50 parts of Cortex Lycii, 30 parts of Radix Angelicae Pubescentiss, 100 parts of Massa Medicata Fermentata, 100 parts of Pericarpium Citri Reticulataes, 60 parts of Rhizoma Chuanxiongs, 50 parts of Lignum Dalbergiae Odoriferaes, 100 parts of Fructus Trichosanthis, 20 parts of the Rhizoma Pinelliaes, 30 parts of Styrax, 100 parts of Rhizoma Acori Graminei, 60 parts of Radix Angelicae Sinensis, 100 parts of Semen Euryaless, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of rhizoma sparganic, Rhizoma Curcumae 15,150 parts of Rhizoma Cyperi, 100 parts of Radix Curcumaes, 30 parts of Fructus Rosae Laevigatae, 30 parts of Fructus Ligustri Lucidi, 50 parts of Herba Dendrobiis, 50 parts of Rhizoma Polygonati Odorati, 100 parts in Fructus Hordei Germinatus, 50 parts of Rhizoma Alismatis, 40 parts of Semen Plantaginiss, 50 parts of Radix Salviae Miltiorrhizaes, 10 parts of Sanguis Draxonis, 30 parts of Squama Manis (processed), 100 parts of Carapax Trionycis (processed), 100 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Benzoinumes, 50 parts of the Radix Aucklandiae, 50 parts of the Radixs Linderae.
Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into rule
Fixed concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating cerebral palsy of children of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 39 routine patients altogether, wherein male 25 examples, women 14 examples; The oldest person 13 years old, the age reckling has only 1 years old.
Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2～5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats 12 courses of treatment altogether.
The therapeutic evaluation standard
Cure: diet is normal, weight increase, and it is normal to have a rest, and pronunciation and action are normal, and sign is improved fully, and the patient does not have any bad sensation, and mental status is good.
Produce effects: diet is normal, weight increase, and it is normal substantially to have a rest, and pronunciation and action significantly improve, and sign is improved near normal, and the patient does not have bad sensation substantially, and mental status is good.
Effectively: diet is normal, weight increase, and it is normal to have a rest, and pronunciation and action are normal substantially, and the sign major part makes moderate progress, and mental status takes a turn for the better.
Invalid: sign changes not obvious, and diet and body weight slightly increase, and lethargy is depressed.
Model case:
1, Wu so-and-so, woman, 2 years old.
From the birth hypoevolutism, during to 1 one full year of life, still can not walk, the beginning head of a family does not take notice of, the back finds that its element that influences the brain function is seriously excessive when once checking, cause the brain function ateliosis, be diagnosed as: cerebral palsy http://www.yuansu120.com/, the head of a family very is worried, tosses about in bed the various big hospital treatment afterwards and does not all feel any better infant limbs contracture, slow movement, sitting shakiness, the commentaries on classics neck that can not come back can only be liied in bed.
Took Chinese medicine composition of the present invention 1 month, head can own freely rotate, and can sit in bed under the head of a family's help.After 1 month, under the head of a family helps, begin the walking exercise continue clothes Chinese medicine composition of the present invention.Continue and obeyed Chinese medicine composition of the present invention 4 months, can oneself stand substantially, and can hold up thing to squat down and oneself stand up, it is still unstable to walk, and also needs assisting in of the head of a family.It is surplus June to obey Chinese medicine composition of the present invention again, and symptom disappears substantially, can ownly freely play, and walks substantially freely, and body weight and diet heighten.
2, Chen, man, 3 years old.
The patient moving phylogeny is slow, just can stand up about eight or nine months, just slowly can sit after 13 months, can creep during two October, can hold up the station in the time of two years old and holds up away, and two upper limb muscular tension can not have, and two muscle tension of lower extremities are high slightly, two ankles shake contraction positives.
Took Chinese medicine composition of the present invention 1 month, the extremity muscular tension obviously reduces, and activity before increases.Continue and obeyed Chinese medicine composition of the present invention 2 months, prop up and do not have cross-legged progression when walking.Continue and obeyed Chinese medicine composition of the present invention 2 months, can fully solely stand, both feet land, and can independently fully walk about 40 meters forward, and the clothes Chinese medicine composition of the present invention that continues is surplus July, and symptom disappears substantially, and appearance be it seems and normal child of the same age and indistinction.
3, river, woman, 1.5 years old.
Have difficult labour during birth, suffocate, little face is suppressed livid purplely, and the doctor rescues and just cries out sound half a day.Body constitution always a little less than, the each sucking seldom, and the milk of often choking, the arm lower limb is also all soft, to 10 wheat harvesting periods, neither can sit and can not climb, it also is inadequate standing up, and the head of a family thinks, a little less than child's body constitution, Motor development a little later is normal, can arrive 1 years old after, when helping her to stand, she only uses tiptoe and lands, endways armful the time, she also always intersects two shanks with strength her, and, can be as child of the same age, with the hope of language performance oneself, go to hospital to do inspection, be diagnosed as cerebral palsy of children.
Took Chinese medicine composition of the present invention 1 month, the both legs crossover phenomenon takes a turn for the better to some extent, and the active performance that is intended to is arranged.The clothes Chinese medicine composition of the present invention 2 months that continues, holding up can both feet land stands, and begins to have simple language.The clothes Chinese medicine composition of the present invention 3 months that continues can hold up object can stand alone substantially, and can squat down voluntarily and stand, and it is unstable to walk, and still needs the head of a family to assist in.It is surplus June to obey Chinese medicine composition of the present invention again, and it is normal substantially to walk, and language is comparatively smooth, can ownly freely play, and symptom disappears substantially.
4, the letter certain, man, 1 years old 8 months.
Owing to suffer from icterohepatitis during birth, cause child's defectiveness in normal development, current diagnosis is a cerebral palsy.Trick is twitched when being admitted to hospital, and can not walk, and tension force is higher, is opisthotonus, and intelligence is normal, and the language competence that speaks is poor.Though child is little, father and mother are being with child constantly to seek medical advice and medicine, but child's the state of an illness does not still have significant change.
Took Chinese medicine composition of the present invention 15 days, muscular tension obviously reduces.Continue and obeyed Chinese medicine composition of the present invention 1 month, the activity desire is stronger, can land by both feet under layman's the help.Continue and obeyed Chinese medicine composition of the present invention 3 months, can stand alone, under the head of a family's assisting in, can walk about 30 meters.It is surplus June to obey Chinese medicine composition of the present invention again, basic auxodrome near normal child of the same age, and body weight, height, dietary amount etc. are normal substantially, can ownly freely play transference cure.
5, Xu certain, woman, 1 years old 6 months.
Suffocate during birth, rescue through oxygen uptake and revive, hospitalization is observed first quarter moon and is returned home the neonatal period peace and quiet.Two lower limb are outer exhibition position, dorsal position, and are one's lips quivering when breast-feeding, and suction is fair unable, and bicker is overflow and suckled.Local in the time of 1 month by " low Ca " treatment 6 months.Still can not climb in the time of 8 months, can not erect head, can not stand up, often cry and scream and do not stop.Inspection is diagnosed as: cerebral palsy of children.
Took Chinese medicine composition of the present invention 15 days, and cry and screamed and gradually end, the infant emotion is gradually stable.Continue and obeyed Chinese medicine composition of the present invention 2 months, can sit, come back, can stand up, can climb, can understand simple instruction.The clothes Chinese medicine composition of the present invention 3 months that continues can be kneeled → stand from seats → height voluntarily, can walk alone, and it is wide slightly to go on foot base, and two upper limb sample of slightly carrying a load can be creeped from hands knee joint position, squats voluntarily.It is surplus June to obey Chinese medicine composition of the present invention again, and handheld toy is played substantially freely, and the extremity muscular tension is not high, and each range of motion of lower limb is normal, and above-mentioned symptom disappears substantially.
6, Liu so-and-so, woman, 2 years old 9 months.
Infant suffocates when giving birth in 7 wheat harvesting period premature labors, sclerosis of the skin, a week in couveuse, oxygen therapy.Leave hospital through rescuing the symptom improvement.Its head of a family is at infant in the time of 1 years old 6 months, finds child's commentaries on classics neck that still can not come back, and arrives examination in hospital immediately, is diagnosed as " cerebral palsy of children ".Infant lower limb, both thighs abduction are limited, and biped is sagging.
Took Chinese medicine composition of the present invention 15 days, the infant head can lift reluctantly, and head can rotate a little.Continue and obeyed Chinese medicine composition of the present invention 3 months, head can own freely rotate, and is holding up and can stand, and symptom is significantly improved.Continue and obeyed Chinese medicine composition of the present invention 3 months, can oneself stand, lower limb abduction freedom, biped is normal.It is surplus May to obey Chinese medicine composition of the present invention again, and symptom all disappears, and can understand simple instruction, can oneself walk, and freely plays.
7, the rising sun, woman, 5 years old.
The patient was diagnosed as in the time of 2 years old: cerebral palsy of children, multi-treatment does not have improvement.Walking is unstable, and slurred speech lolls, the drum cheek can not, muscular hypertonia is spastic paralysis, the coordinate movement imbalance, dark, superficial sensibility and synaesthesia are mismatched, and walk appearance layback, difficulty.
Took Chinese medicine composition of the present invention 15 days, finger fine movement, the action of closing one's eyes are more preceding flexibly.Continue and obeyed Chinese medicine composition of the present invention 1 month, the more preceding improvement of lower limb walking lolls, rouses the more preceding improvement of the cheek.Continue and obeyed Chinese medicine composition of the present invention 2 months, the more preceding remarkable reduction of muscular tension, ataxia is more preceding to be light, and walking normally can be walked more than 20 meter not to layback, and symptom is greatly taken on a new look.It is surplus June to obey Chinese medicine composition of the present invention again, and symptom all disappears, and language fluency can oneself be walked freely.
8, Yin so-and-so, man, 13 years old.
Also no abnormal during the infant birth, along with growth promoter, it is slower that the head of a family only thinks that child grows, and other aspects have no difference with normal child, thereby are not paid attention to.
After 3 years old, can send out monosyllabic word, and only can be " father ", other all can not.To 5 years old the time, still can not oneself have a meal, even during head of a family's feeding, also be what what eat to, just do not eaten.A head of a family found that to Fructus Mali pumilae of plug in his hands, during infant is hand held, does not eat also and does not abandon, and holds when play daytime, and sleep is not at night still put, and this allows the head of a family think that problem is much more serious than what imagine down.So seek medical advice and medicine everywhere, still loseed any improvement sign until 13 o'clock, the head of a family entertains hope hardly.
Accidental chance, the infant father hears that the expert of particularly autocratic difficult disease returns to one's home village, and just is with infant to seek medical advice together.Be the natural endowment deficiency after diagnosing, lose the day after tomorrow and support that hide gas and do not fill, hypoevolutism is to be cerebral palsy.
Through taking Chinese medicine composition of the present invention room 1 month, pronunciation obviously improves, and can be " grandmother " vaguely, and this allows the head of a family very be moved.Follow-uply take Chinese medicine composition of the present invention after 2 months, verbalization is clear, and thinking is more clear, and diet, rest, activity etc. are normal fully.And to taking pharmaceutical composition of the present invention in the time of 3rd month, the head of a family is souning out and is allowing infant oneself do shopping, and observes silently subsequently, and the head of a family is frightened as a result, and oneself can finish infant unexpectedly.Obey Chinese medicine composition of the present invention June again, each side has all reached normal child's of the same age standard, and vivaciously active, symptom all disappears, and goes to school, and achievement is medium.
Five, therapeutic outcome:
In the 39 routine cases of being accepted for medical treatment,, wherein cure 5 examples through treatment in 12 months, produce effects 12 examples, effective 8 examples, invalid 14 examples, total effective rate reaches 64%.The result shows, Chinese medicine composition of the present invention has Chinese medicine composition of significant curative effect extremely and preparation method thereof to the treatment cerebral palsy of children.
Claims (4)
1. Chinese medicine composition for the treatment of cerebral palsy of children, it is characterized in that: the weight portion of each crude drug is:
50 parts of Radix Codonopsis, 100 parts of Radix Astragali, 15 parts of Radix Ginsengs, 10 parts of Radix Panacis Quinquefoliis, 60 parts of the Radix Paeoniae Albas, 50 parts of Fructus Alpiniae Oxyphyllae, 30 parts of Radix Achyranthis Bidentataes, 100 parts of Rhizoma Dioscoreaes, 50 parts of Fructus Lycii, 30 parts of Rhizoma Et Radix Notopterygiis, 20 parts of the Radixs Angelicae Dahuricae, 10 parts of Herba Menthaes, 150 parts of Radix Puerariaes, 30 parts of Flos Chrysanthemis, 50 parts of Radix Trichosanthis, 30 parts of Semen Cassiaes, 50 parts of Radix Scutellariaes, 30 parts of Rhizoma Coptidis, 30 parts of Radix Rehmanniae Preparata, 30 parts of Radix Salviae Miltiorrhizaes, 50 parts of Radix Notoginseng, 30 parts of Radix Et Rhizoma Rhei, 50 parts of Cortex Lycii, 30 parts of Radix Angelicae Pubescentiss, 100 parts of Massa Medicata Fermentata, 100 parts of Pericarpium Citri Reticulataes, 60 parts of Rhizoma Chuanxiongs, 50 parts of Lignum Dalbergiae Odoriferaes, 100 parts of Fructus Trichosanthis, 20 parts of the Rhizoma Pinelliaes, 30 parts of Styrax, 100 parts of Rhizoma Acori Graminei, 60 parts of Radix Angelicae Sinensis, 100 parts of Semen Euryaless, 50 parts of Radix Ophiopogonis, 50 parts of Radix Asparagi, 15 parts of rhizoma sparganic, Rhizoma Curcumae 15,150 parts of Rhizoma Cyperi, 100 parts of Radix Curcumaes, 30 parts of Fructus Rosae Laevigatae, 30 parts of Fructus Ligustri Lucidi, 50 parts of Herba Dendrobiis, 50 parts of Rhizoma Polygonati Odorati, 100 parts in Fructus Hordei Germinatus, 50 parts of Rhizoma Alismatis, 40 parts of Semen Plantaginiss, 50 parts of Radix Salviae Miltiorrhizaes, 10 parts of Sanguis Draxonis, 30 parts of Squama Manis (processed), 100 parts of Carapax Trionycis (processed), 100 parts of Carapax Et Plastrum Testudinis (processed), 30 parts of Benzoinumes, 50 parts of the Radix Aucklandiae, 50 parts of the Radixs Linderae.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that: the method for Chinese medicinal according to routine is prepared into any oral formulations commonly used.
3. according to the described Chinese medicine composition of claim 2, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
4. the application of any described Chinese medicine composition of claim 1～3 in preparation treatment cerebral palsy of children medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010103004434A CN101757572B (en) | 2010-01-19 | 2010-01-19 | Traditional Chinese medicine composition for treating infantile cerebral palsy and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010103004434A CN101757572B (en) | 2010-01-19 | 2010-01-19 | Traditional Chinese medicine composition for treating infantile cerebral palsy and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101757572A CN101757572A (en) | 2010-06-30 |
| CN101757572B true CN101757572B (en) | 2011-04-27 |
Family
ID=42489056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010103004434A Expired - Fee Related CN101757572B (en) | 2010-01-19 | 2010-01-19 | Traditional Chinese medicine composition for treating infantile cerebral palsy and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101757572B (en) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101869600A (en) * | 2010-07-05 | 2010-10-27 | 成都中医药大学 | Medicinal composition for treating degenerative change in central nervous system, preparation method and application thereof |
| CN102125663B (en) * | 2010-10-27 | 2012-07-25 | 宋爱民 | Traditional Chinese medicinal preparation for treating cerebral concussion |
| CN102008676B (en) * | 2010-11-29 | 2011-12-28 | 宋兆普 | Chinese medicinal powder for treating cerebral palsy |
| CN102526397B (en) * | 2012-01-12 | 2013-06-05 | 高新华 | Medicament for treating salivation |
| CN102579974B (en) * | 2012-02-15 | 2013-06-12 | 高玉元 | Chinese medicinal wearing bag for treating cerebral palsy |
| CN102579956B (en) * | 2012-03-23 | 2013-10-23 | 长沙高新开发区鷁巢生物科技有限公司 | Medicament composition and application thereof |
| CN103893667B (en) * | 2014-04-18 | 2016-08-24 | 河北联合大学 | The Chinese medicine for the treatment of subacute combined degeneration of spinal cord disease and the preparation of compound dripping pill |
| CN104474299A (en) * | 2014-11-21 | 2015-04-01 | 郝建国 | Intelligence-reinforcing traditional Chinese medicinal preparation for treating pediatric atelencephalia and preparation method thereof |
| CN104474300A (en) * | 2014-11-21 | 2015-04-01 | 郝建国 | Traditional Chinese medicine composition for treating congenital maldevelopment of brain and preparation method |
| CN104306748A (en) * | 2014-11-21 | 2015-01-28 | 郝建国 | Traditional Chinese medicine combination for treating child atelencephalia and preparing method thereof |
| CN104352818A (en) * | 2014-11-21 | 2015-02-18 | 郝建国 | Traditional Chinese medicine composition for treating atelencephalia and preparation method thereof |
| CN104352817A (en) * | 2014-11-21 | 2015-02-18 | 郝建国 | Traditional Chinese medicine preparation for treating cerebral agenesis and preparation method thereof |
| CN104666997A (en) * | 2015-02-11 | 2015-06-03 | 郭如英 | Oral liquid for treating intellectual development retardation and preparation |
| CN104840862B (en) * | 2015-05-15 | 2018-05-01 | 宋毅鹏 | Brain tonic stops convulsion particle |
| CN105106760A (en) * | 2015-09-30 | 2015-12-02 | 山东大学齐鲁医院 | Traditional Chinese medicine for treating infantile cerebral palsy and preparation method of traditional Chinese medicine |
| CN107929552A (en) * | 2017-11-26 | 2018-04-20 | 杨韶彰 | Treat the Chinese medicine of brain paralysis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101112474A (en) * | 2007-08-15 | 2008-01-30 | 吕卫荣 | Chinese herbal medicine preparations for treating cerebral pasly through immersion |
-
2010
- 2010-01-19 CN CN2010103004434A patent/CN101757572B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101112474A (en) * | 2007-08-15 | 2008-01-30 | 吕卫荣 | Chinese herbal medicine preparations for treating cerebral pasly through immersion |
Non-Patent Citations (2)
| Title |
|---|
| 江冬生.推拿配合中药在治疗小儿脑瘫中的应用价值.《中国医药指南》.2009,第7卷(第15期),116-117. * |
| 谭工,等.治疗小儿脑瘫18例临床观察.《四川中医》.2008,第26卷(第10期),88-89. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101757572A (en) | 2010-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101757572B (en) | Traditional Chinese medicine composition for treating infantile cerebral palsy and preparation method thereof | |
| CN101716322B (en) | Traditional Chinese medicine composition for treating heart-blood deficiency disease and preparation method thereof | |
| CN101711850B (en) | Traditional Chinese medicine composition for treating symptoms of myocardial ischemia, palpitation and severe palpitation and preparation method | |
| CN101757569A (en) | Traditional Chinese medicine composition for treating cerebral thrombosis and cerebral infarction and preparation method thereof | |
| CN101537168B (en) | Traditional Chinese medicine composition for treatment of cervical spondylopathy and osteoarticular diseases and preparation method thereof | |
| CN101693099B (en) | Traditional Chinese medicine composite for treating tachyrhythmia and its preparation method | |
| CN101785845B (en) | Traditional Chinese medicine combination and preparation method for intestinal flatulence treatment | |
| CN101766802B (en) | Chinese medicine composite for treatment of acute gastroenteritis and preparation method thereof | |
| CN101810833B (en) | Chinese medicinal composition for treating edema and preparation method thereof | |
| CN101804169A (en) | Traditional Chinese medicine composition for treating urinary incontinence and preparation method thereof | |
| CN101732616B (en) | Chinese medicinal composition for treating intracerebral hemorrhage and preparation method thereof | |
| CN101810801A (en) | Chinese medicinal composition for treating hypertension and preparation method thereof | |
| CN101773622A (en) | Chinese medicinal composition for treating night sweats and preparation method thereof | |
| CN101773634A (en) | Chinese medicine composition for treating abdominal distention and fullness and preparation method thereof | |
| CN101810835A (en) | Chinese medicinal composition for treating purpura and preparation method thereof | |
| CN101810792B (en) | Chinese medicinal composition for treating kidney failure diseases and preparation method thereof | |
| CN101791391A (en) | Traditional Chinese medicine composition for treatment of cardiovascular infarction syndrome and preparation method thereof | |
| CN101874879A (en) | Chinese medicinal composition for treating osteopyrexia and preparation method thereof | |
| CN101966319A (en) | Traditional Chinese medicinal composition for treating dizziness during menstruation and preparation method thereof | |
| CN101757570B (en) | Traditional Chinese medicine composition for treating cerebellar atrophy and preparation method thereof | |
| CN101623409B (en) | Traditional Chinese medicine preparation for treating apoplexy | |
| CN101590104A (en) | A kind of Chinese medicine for the treatment of obstructive angiitis | |
| CN101810787A (en) | Chinese medicinal composition for treating dysphoria and preparation method thereof | |
| CN101843888B (en) | Novel Chinese medicinal composition for treating menorrhagia and a preparation method thereof | |
| CN103028089B (en) | Traditional Chinese medicine composition for treating waist pains of middle-aged and old people |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110427 Termination date: 20140119 |