CN101716330B - Traditional Chinese medicine composition for treating angina disease and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating angina disease and preparation method thereof Download PDF

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Publication number
CN101716330B
CN101716330B CN2009103099747A CN200910309974A CN101716330B CN 101716330 B CN101716330 B CN 101716330B CN 2009103099747 A CN2009103099747 A CN 2009103099747A CN 200910309974 A CN200910309974 A CN 200910309974A CN 101716330 B CN101716330 B CN 101716330B
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radix
rhizoma
chinese medicine
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CN101716330A (en
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王峰
王文奎
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Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
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Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine composition for treating an angina disease and a preparation method thereof. The traditional Chinese composition is prepared from the following raw medical materials: citrus aurantium, rhizoma chuanxiong, curcuma longa, olibanum, myrrh, bupleurum, tambac, radix auckladiae, cyperus tuber, radix linderae, chinaberry fruit, aristolochia debilis,areca peel, macrostem onion, sandalwood, fingered citron, citron, aspongopus, cinnamon, dry ginger, evodia, cloves, common fennel, galangal, fumitory, curcuma, rhubarb, red sage roots, safflower, peach kernel, sapanwood, gurcuma, trigone, pangolin, storax, benzoin, camphor, borneol, acorus gramineous, angelica, white peony, cassia twig, asarum, notopterygium, angelica dahurica and prepared rhizome of rehmannia. The traditional Chinese composition can be prepared into any common oral preparation according to a general traditional Chinese composition method, can obviously relieve various pains on the mid-upper part of the breastbone due to the paroxysm of the angina, have clinical determined curative effect and rapid action, basically adopts medicaments in homology of medicine and food for composition and has the advantages of low expense, basic toxic and side effect prevention, and the like.

Description

A kind of Chinese medicine composition for the treatment of angina disease and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of angina disease.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment angina disease of crude drug with the Chinese herbal medicine.
Background technology
Chest pain, precordialgia disease all easily take place in natural endowment deficiency, exopathogen invasion and attack, the improper addiction to greasy and sweet foods savoury of diet http://www.aliyiyao.com/food/ or frequent heavy meal are excessive, disorder of emotion melancholy impairing the spleen etc.Be pain between uncomfortable in chest, breast breast, the back of the body, omoplate, pain in the medial sides of both arms, lose heart etc. is a kind of common ambition disease of feature, and the lighter is Danzhong or chest is felt oppressed, pain only, can be with cardiopalmus, weight person's chest pain radiating to the back, backache radiating to the heart, sharp ache and continue and can not alleviate, it is contrary that extremity are fainted, pale complexion, dripping cold sweat, faint pulse being about to disappear, onset of disease in the morning and dying in the evening, onset of disease in the evening and dying in the next morning, have a strong impact on Health and Living, the clinical onset rate has the trend of continuous rising in recent years.
Modern medicine is at clinical a certain symptom treatment, often fall flat, can not find suitable Therapeutic Method, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment angina disease, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical accent, emergency is taken in concurrently, filter out the natural plant of dredging regulating QI machine, blood circulation promoting and blood stasis dispelling, coronary circulation-promoting pain-relieving,, be prepared from according to certain weight proportion according to the theory of Chinese medical science prescription.A kind of evident in efficacy, with low cost, treatment chest pain that toxic and side effects is minimum, the Chinese medicine composition of pained disease are provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment angina disease of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of angina disease of the present invention, the component of main following weight portion is formed:
Fructus Aurantii Immaturus 1~150 gram, Rhizoma Chuanxiong 1~100 gram, Radix Curcumae 1~100 gram, Olibanum 1~50 gram, Myrrha 1~50 gram, Radix Bupleuri 1~100 gram, Lignum Aquilariae Resinatum 1~50 gram, the Radix Aucklandiae 1~100 gram, Rhizoma Cyperi 1~150 gram, the Radix Linderae 1~100 gram, Fructus Toosendan 1~150 gram, Radix Aristolochiae 1~100 gram, Pericarpium Arecae 1~100 gram, Bulbus Allii Macrostemonis 1~100 gram, Lignum Santali Albi 1~50 gram, Fructus Citri Sarcodactylis 1~100 gram, Fructus Citri 1~100 gram, Aspongopus 1~50 gram, Cortex Cinnamomi 1~50 gram, Rhizoma Zingiberis 1~100 gram, Fructus Evodiae 1~90 gram, Flos Caryophylli 1~30 gram, Fructus Foeniculi 1~60 gram, Rhizoma Alpiniae Officinarum 1~100 gram, Rhizoma Corydalis 1~100 gram, Rhizoma Curcumae Longae 1~100 gram, Radix Et Rhizoma Rhei 1~100 gram, Radix Salviae Miltiorrhizae 1~100 gram, Flos Carthami 1~60 gram, Semen Persicae 1~60 gram, Lignum Sappan 1~50 gram, Rhizoma Curcumae 1~50 gram, rhizoma sparganic 1~50 gram, Squama Manis 1~100 gram.
Be preferably:
Fructus Aurantii Immaturus 100 grams, Rhizoma Chuanxiong 30 grams, Radix Curcumae 30 grams, Olibanum 15 grams, Myrrha 15 grams, Radix Bupleuri 30 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, the Radix Linderae 50 grams, Fructus Toosendan 50 grams, Radix Aristolochiae 40 grams, Pericarpium Arecae 30 grams, Bulbus Allii Macrostemonis 20 grams, Lignum Santali Albi 20 grams, Fructus Citri Sarcodactylis 30 grams, Fructus Citri 30 grams, Aspongopus 10 grams, Cortex Cinnamomi 20 grams, Rhizoma Zingiberis 20 grams, Fructus Evodiae 20 grams, Flos Caryophylli 10 grams, Fructus Foeniculi 10 grams, Rhizoma Alpiniae Officinarum 20 grams, Rhizoma Corydalis 50 grams, Rhizoma Curcumae Longae 50 grams, Radix Et Rhizoma Rhei 50 grams, Radix Salviae Miltiorrhizae 30 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Lignum Sappan 30 grams, Rhizoma Curcumae 15 grams, rhizoma sparganic 15 grams, Squama Manis 10 grams.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
Cinnabaris 1~20 gram, Os Draconis 1~100 gram, Concha Ostreae 1~100 gram, Semen Ziziphi Spinosae 1~100 gram, Semen Platycladi 1~100 gram, Cortex Albiziae 1~100 gram, Radix Polygalae 1~50 gram, Caulis Polygoni Multiflori 1~100 gram, Moschus 1~10 gram, Styrax 1~100 gram, Benzoinum 1~100 gram, Camphora 1~50 gram, Borneolum Syntheticum 1~50 gram, Rhizoma Acori Graminei 1~150 gram, Radix Codonopsis 1~100 gram, Radix Angelicae Sinensis 1~300 gram, the Radix Paeoniae Alba 1~150 gram, the Rhizoma Atractylodis Macrocephalae 1~150 gram, Rhizoma Dioscoreae 1~300 gram, Fructus Trichosanthis 1~300 gram, Semen Lepidii (Semen Descurainiae) 1~100 gram, Fructus Schisandrae Chinensis 1~100 gram, Semen Pruni 1~100 gram, Ramulus Cinnamomi 1~100 gram, Herba Asari 1~30 gram, Rhizoma Et Radix Notopterygii 1~100 gram, Herba Schizonepetae 1~60 gram, the Radix Angelicae Dahuricae 1~50 gram, Radix Rehmanniae Preparata 1~150 gram.
Be preferably:
Cinnabaris 5 grams, Os Draconis 20 grams, Concha Ostreae 20 grams, Semen Ziziphi Spinosae 20 grams, Semen Platycladi 20 grams, Cortex Albiziae 20 grams, Radix Polygalae 20 grams, Caulis Polygoni Multiflori 30 grams, Moschus 1 gram, Styrax 30 grams, Benzoinum 30 grams, Camphora 10 grams, Borneolum Syntheticum 10 grams, Rhizoma Acori Graminei 50 grams, Radix Codonopsis 30 grams, Radix Angelicae Sinensis 100 grams, the Radix Paeoniae Alba 50 grams, the Rhizoma Atractylodis Macrocephalae 50 grams, Rhizoma Dioscoreae 100 grams, Fructus Trichosanthis 100 grams, Semen Lepidii (Semen Descurainiae) 30 grams, Fructus Schisandrae Chinensis 40 grams, Semen Pruni 30 grams, Ramulus Cinnamomi 40 grams, Herba Asari 3 grams, Rhizoma Et Radix Notopterygii 20 grams, Herba Schizonepetae 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Rehmanniae Preparata 40 grams.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " clinical fundamental symptoms symptomatic treatment side " is assistant, " therapy of serious disease side " Chinese medicine patent medicine " original new drug system " for making.This is the important content of Thailand one and Pu (Beijing) Chinese medicine academy patent strategy.
The structure of Thailand one and Pu patent strategy is convenient to Chinese medicine and is realized standardization, scale, industrialization, modernization and industrialization.For traditional Chinese medicine development has been opened up a road that meets the Chinese medicine self-law with innovation.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2~5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to the angina disease patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: Fructus Aurantii Immaturus 100 grams, Rhizoma Chuanxiong 30 grams, Radix Curcumae 30 grams, Olibanum 15 grams, Myrrha 15 grams, Radix Bupleuri 30 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, the Radix Linderae 50 grams, Fructus Toosendan 50 grams, Radix Aristolochiae 40 grams, Pericarpium Arecae 30 grams, Bulbus Allii Macrostemonis 20 grams, Lignum Santali Albi 20 grams, Fructus Citri Sarcodactylis 30 grams, Fructus Citri 30 grams, Aspongopus 10 grams, Cortex Cinnamomi 20 grams, Rhizoma Zingiberis 20 grams, Fructus Evodiae 20 grams, Flos Caryophylli 10 grams, Fructus Foeniculi 10 grams, Rhizoma Alpiniae Officinarum 20 grams, Rhizoma Corydalis 50 grams, Rhizoma Curcumae Longae 50 grams, Radix Et Rhizoma Rhei 50 grams, Radix Salviae Miltiorrhizae 30 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Lignum Sappan 30 grams, Rhizoma Curcumae 15 grams, rhizoma sparganic 15 grams, Squama Manis 10 grams, Moschus 1 gram, Styrax 30 grams, Benzoinum 30 grams, Camphora 10 grams, Borneolum Syntheticum 10 grams, Rhizoma Acori Graminei 50 grams, Radix Codonopsis 30 grams, Radix Angelicae Sinensis 100 grams, the Radix Paeoniae Alba 50 grams, Ramulus Cinnamomi 40 grams, Herba Asari 3 grams, Rhizoma Et Radix Notopterygii 20 grams, Herba Schizonepetae 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Rehmanniae Preparata 40 grams.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: Fructus Aurantii Immaturus 100 grams, Rhizoma Chuanxiong 30 grams, Radix Curcumae 30 grams, Olibanum 15 grams, Myrrha 15 grams, Radix Bupleuri 30 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, the Radix Linderae 50 grams, Fructus Toosendan 50 grams, Radix Aristolochiae 40 grams, Pericarpium Arecae 30 grams, Bulbus Allii Macrostemonis 20 grams, Lignum Santali Albi 20 grams, Fructus Citri Sarcodactylis 30 grams, Fructus Citri 30 grams, Aspongopus 10 grams, Cortex Cinnamomi 20 grams, Rhizoma Zingiberis 20 grams, Fructus Evodiae 20 grams, Flos Caryophylli 10 grams, Fructus Foeniculi 10 grams, Rhizoma Alpiniae Officinarum 20 grams, Rhizoma Corydalis 50 grams, Rhizoma Curcumae Longae 50 grams, Radix Et Rhizoma Rhei 50 grams, Radix Salviae Miltiorrhizae 30 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Lignum Sappan 30 grams, Rhizoma Curcumae 15 grams, rhizoma sparganic 15 grams, Squama Manis 10 grams, Moschus 1 gram, Styrax 30 grams, Benzoinum 30 grams, Camphora 10 grams, Borneolum Syntheticum 10 grams, Rhizoma Acori Graminei 50 grams, Radix Codonopsis 30 grams, Radix Angelicae Sinensis 100 grams, the Radix Paeoniae Alba 50 grams, Ramulus Cinnamomi 40 grams, Herba Asari 3 grams, Rhizoma Et Radix Notopterygii 20 grams, Herba Schizonepetae 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Rehmanniae Preparata 40 grams.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material by following weight portion: Fructus Aurantii Immaturus 100 grams, Rhizoma Chuanxiong 30 grams, Radix Curcumae 30 grams, Olibanum 15 grams, Myrrha 15 grams, Radix Bupleuri 30 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, the Radix Linderae 50 grams, Fructus Toosendan 50 grams, Radix Aristolochiae 40 grams, Pericarpium Arecae 30 grams, Bulbus Allii Macrostemonis 20 grams, Lignum Santali Albi 20 grams, Fructus Citri Sarcodactylis 30 grams, Fructus Citri 30 grams, Aspongopus 10 grams, Cortex Cinnamomi 20 grams, Rhizoma Zingiberis 20 grams, Fructus Evodiae 20 grams, Flos Caryophylli 10 grams, Fructus Foeniculi 10 grams, Rhizoma Alpiniae Officinarum 20 grams, Rhizoma Corydalis 50 grams, Rhizoma Curcumae Longae 50 grams, Radix Et Rhizoma Rhei 50 grams, Radix Salviae Miltiorrhizae 30 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Lignum Sappan 30 grams, Rhizoma Curcumae 15 grams, rhizoma sparganic 15 grams, Squama Manis 10 grams, Moschus 1 gram, Styrax 30 grams, Benzoinum 30 grams, Camphora 10 grams, Borneolum Syntheticum 10 grams, Rhizoma Acori Graminei 50 grams, Radix Codonopsis 30 grams, Radix Angelicae Sinensis 100 grams, the Radix Paeoniae Alba 50 grams, Ramulus Cinnamomi 40 grams, Herba Asari 3 grams, Rhizoma Et Radix Notopterygii 20 grams, Herba Schizonepetae 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Rehmanniae Preparata 40 grams.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800~1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material by following weight portion: Fructus Aurantii Immaturus 100 grams, Rhizoma Chuanxiong 30 grams, Radix Curcumae 30 grams, Olibanum 15 grams, Myrrha 15 grams, Radix Bupleuri 30 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, the Radix Linderae 50 grams, Fructus Toosendan 50 grams, Radix Aristolochiae 40 grams, Pericarpium Arecae 30 grams, Bulbus Allii Macrostemonis 20 grams, Lignum Santali Albi 20 grams, Fructus Citri Sarcodactylis 30 grams, Fructus Citri 30 grams, Aspongopus 10 grams, Cortex Cinnamomi 20 grams, Rhizoma Zingiberis 20 grams, Fructus Evodiae 20 grams, Flos Caryophylli 10 grams, Fructus Foeniculi 10 grams, Rhizoma Alpiniae Officinarum 20 grams, Rhizoma Corydalis 50 grams, Rhizoma Curcumae Longae 50 grams, Radix Et Rhizoma Rhei 50 grams, Radix Salviae Miltiorrhizae 30 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Lignum Sappan 30 grams, Rhizoma Curcumae 15 grams, rhizoma sparganic 15 grams, Squama Manis 10 grams, Moschus 1 gram, Styrax 30 grams, Benzoinum 30 grams, Camphora 10 grams, Borneolum Syntheticum 10 grams, Rhizoma Acori Graminei 50 grams, Radix Codonopsis 30 grams, Radix Angelicae Sinensis 100 grams, the Radix Paeoniae Alba 50 grams, Ramulus Cinnamomi 40 grams, Herba Asari 3 grams, Rhizoma Et Radix Notopterygii 20 grams, Herba Schizonepetae 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Rehmanniae Preparata 40 grams.
Each raw material of above-mentioned weight is mixed, grind into cross 600~1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material by following weight portion: Fructus Aurantii Immaturus 100 grams, Rhizoma Chuanxiong 30 grams, Radix Curcumae 30 grams, Olibanum 15 grams, Myrrha 15 grams, Radix Bupleuri 30 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, the Radix Linderae 50 grams, Fructus Toosendan 50 grams, Radix Aristolochiae 40 grams, Pericarpium Arecae 30 grams, Bulbus Allii Macrostemonis 20 grams, Lignum Santali Albi 20 grams, Fructus Citri Sarcodactylis 30 grams, Fructus Citri 30 grams, Aspongopus 10 grams, Cortex Cinnamomi 20 grams, Rhizoma Zingiberis 20 grams, Fructus Evodiae 20 grams, Flos Caryophylli 10 grams, Fructus Foeniculi 10 grams, Rhizoma Alpiniae Officinarum 20 grams, Rhizoma Corydalis 50 grams, Rhizoma Curcumae Longae 50 grams, Radix Et Rhizoma Rhei 50 grams, Radix Salviae Miltiorrhizae 30 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Lignum Sappan 30 grams, Rhizoma Curcumae 15 grams, rhizoma sparganic 15 grams, Squama Manis 10 grams, Moschus 1 gram, Styrax 30 grams, Benzoinum 30 grams, Camphora 10 grams, Borneolum Syntheticum 10 grams, Rhizoma Acori Graminei 50 grams, Radix Codonopsis 30 grams, Radix Angelicae Sinensis 100 grams, the Radix Paeoniae Alba 50 grams, Ramulus Cinnamomi 40 grams, Herba Asari 3 grams, Rhizoma Et Radix Notopterygii 20 grams, Herba Schizonepetae 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Rehmanniae Preparata 40 grams.
Each raw material of above-mentioned weight is mixed, after decocting for three times, three filtrates is mixed, filter, be concentrated into the concentration of regulation, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating angina disease of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 135 routine patients altogether, wherein male 59 examples, women 76 examples; The oldest person 68 years old, the age reckling has only 22 years old.
Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2~5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 5 courses of treatment altogether.
The therapeutic evaluation standard
Cure: sign is improved fully, and the patient does not have any bad sensation, and is happy, in high spirits.
Produce effects: sign is significantly improved, and the patient does not have bad sensation substantially, and is happy, and spirit is fine.
Effectively: sign obviously changes, and random thoughts have discomfort slightly, but can accept, and mood is better, and energy is more abundant.
Invalid: sign does not have any change, symptom such as preceding, and mood is gloomy, lassitude.
Model case:
1, poplar, man, 43 years old, manager.
Suffered from chest pain, pained disease before 2 years, once obeyed the attached lizhong decoction in osmanthus, reuse Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae and add Radix Angelicae Sinensis, clothes backs disease is not seen and is subtracted.Whenever in the outbreak, pain is scooped up in ambition, and just like stagnation of QI in the chest, very then the thorough shoulder of the pain back of the body is no longer capable of either eating or drinking, the anxious then face lip pastiness of pain, dripping cold sweat, the cold pain of sense very, sensation of oppression over the chest with shortness of breath, cardiopalmus, heavy then pant, can not put down for sleeping in, pale complexion, extreme cold of the limbs, tongue fur is white, deep-thready pulse.
Take Chinese medicine composition of the present invention after 15 days, pain relief, sensation of oppression over the chest with shortness of breath is alleviated, extremity are temperature gradually, continues and obeys Chinese medicine composition of the present invention 1 month, and pain continues to alleviate, uncomfortable in chest gradually easypro, it is fixed that cardiopalmus becomes, and continues and obeyed Chinese medicine composition of the present invention 2 months, pain is not done, and has rosy cheeks, and ambition is happy, normal fully, followed up a case by regular visits to 2 years, situation is stable, not recurrence.
2, Zhu, woman, 57 years old, retired employees.
Once be diagnosed as " coronary heart disease, ischemic angina pectoris ", hospitalization takes a turn for the better, leave hospital soon, chest pain, pained multiple the work, pain is led and the homonymy omoplate on the left side of breast breast, and a number of days is sent out, though the persistent period is not long, but the pain gesture is quite heavy, and is nervous with cold extremities, and normal at ordinary times sense is uncomfortable in chest, activity is stepped on the building and is then breathed hard deposited, the idol had palpitation, it is short unreal to sleep, dizzy tired finger fiber crops, sometimes afternoon low grade fever, once used Western medicine persantin, ATP, sorbitrate, nitroglycerine tablets and FUFANG DANSHEN PIAN etc. all can not control its outbreak, thin fur, the rich indentation in tongue limit, arteries and veins shape is carefully puckery.
Take Chinese medicine composition of the present invention after 15 days, chest pain, pained alleviating, alleviation uncomfortable in chest, the more preceding minimizing of attack times, extremity be temperature gradually, continues and obeys Chinese medicine composition of the present invention 1 month, chest pain, pained continuation are alleviated, and show effect once afternoon little feel flesh heat in several days, nervous gradually fixed, sleep takes a turn for the better, and can suitably do a little housework, continue and obeyed Chinese medicine composition of the present invention 2 months, pain is not done, and has rosy cheeks, ambition is happy, and symptom all disappears, and the building is stepped in activity has not had discomfort.
3, Gong, woman, 48 years old, accounting.
Nearly 10 years of hypertension history was suffered from cerebral thrombosis and the paralysis of right half body before 6 years, the vexed pain in front or with radioactivity shoulder back dull pain is pained in the recent period, xerostomia hardship, cardiopalmus dysphoria with smothery sensation, night sweat, the not peacefully sleeping of sleeping, difficulty in defecation, chaude-pisse.Thready and stringy pulse, red tongue with thin and yellow fur.
Take Chinese medicine composition of the present invention after 10 days, chest pain, pained alleviating, alleviation uncomfortable in chest, night sweat gradually ends, and continues and obeys Chinese medicine composition of the present invention 1 month, and chest pain, pained continuation take a turn for the better, cardiopalmus is gradually fixed, the sleep amelioration, symptom is greatly taken on a new look, and continues and obeys Chinese medicine composition of the present invention 2 months, two is just normal, pain is not done, and ambition is happy, and patient's life and work is normal.
4, Wang, woman, 40 years old, teacher.
Because of uncomfortable in chest, shortness of breath and fatigue does not freely appear in feelings will, the electrocardiogram prompting: sinus bradycardia, myocardial ischemia, oral storax pill for treating coronary heart disease, sorbitrate are not all alleviated before half a year.Increased the weight of for 1 week and examine, the patient uncomfortable in chest and the pain, pained, breathe hard fatigue and weakness, anorexia, soreness of the waist and knees, coldness of the body with chills.The few China of pale complexion, xerosis cutis, extremities being not warm, light red tongue, tongue are white, deep-slow pulse.
Take Chinese medicine composition of the present invention after 7 days, chest pain, painedly subtract slightly, extremity are temperature gradually, alleviation uncomfortable in chest continues and obeyed Chinese medicine composition of the present invention 20, chest pain, pained alleviation, breathing hard alleviates, the sleep amelioration, and diet increases, continue and obeyed Chinese medicine composition of the present invention 1 month, pain disappears substantially, and spirit is gradually shaken, complexion takes a turn for the better, and symptom is greatly taken on a new look, and obeys Chinese medicine composition of the present invention again 1 month, symptom all disappears, and breathes smooth and easy, energetic.
5, Lee, woman, 54 years old, shop assistant.
Patient's paroxysmal precordial fullness is half a year bitterly, outbreak repeatedly, day 3-5 time, whenever in the outbreak in, ambition scoop up the pain, just like stagnation of QI in the chest, very then the thorough shoulder of pain is carried on the back, hospitalization 1 month, and nothing is clearly better, take traditional Chinese medicine and nurse one's health the commentaries on classics of also not getting better, patient's malaise is breathed hard, indigestion and loss of appetite, be afraid of cold the lower limb cold, slow pulse, the fat dim indentation that has of light red tongue, electrocardiogram shows: ST-T changes.
Take Chinese medicine composition of the present invention after 15 days, the ambition pain relief, lower limb are temperature gradually, attack times reduces, and continues and obeys Chinese medicine composition of the present invention 20, and ambition pain continues to take a turn for the better, breathing hard alleviates, and receives to increase, and 2-3 day shows effect once, continue and obeyed Chinese medicine composition of the present invention 1 month, ambition pain disappears substantially, and spirit is gradually shaken, symptom is greatly taken on a new look, and obeys Chinese medicine composition of the present invention again 1 month, and the check electrocardiogram is normal, breathe smooth and easyly, energetic, symptom all disappears.
6, Zhang, man, 42 years old, cadre.
Before 1 year the patient hospitalization is after 3 months with " angina pectoris, myocardial infarction ", the state of an illness is basicly stable, leaves hospital.The vexed pain of the normal sense of pareordia in the recent period, right arm has feeling of numbness, hyperhidrosis sometimes, oliguria, unexpected chest pain radiating to the back before the week, dyspnea, nervous cardiopalmus, outbreak, hospitalization once more repeatedly, the commentaries on classics of not getting better sees when examining that lip is purplish red, spiritlessness and weakness, sclera is full of the blood streak, and finger expands red, and tongue body light is red, arrhythmia, the left hand volt is hidden, and the right hand is slow.
Take Chinese medicine composition of the present invention after 15 days, the ambition pain relief, nervous cardiopalmus alleviates, the sclera blood streak obviously reduces, and attack times reduces, and continues and obeys Chinese medicine composition of the present invention 1 month, ambition pain is significantly improved, and attack times obviously reduces, and it is fixed that nervous cardiopalmus becomes, spirit is gradually shaken, and symptom is greatly taken on a new look, and obeys Chinese medicine composition of the present invention again 1 month, symptom all disappears, breathe smooth and easyly, lip is ruddy, and is energetic.
7, Cao, man, 69 years old, peasant.
Readme cardiopalmus, precordialgia 5~6 years gradually increase the weight of after the beginning is light, and attack times constantly increases, and the companion is dizzy, breathes hard, and cold extremities is weak, premature beat often occurs, gives Drug therapys such as atropine, sorbitrate, nicotiamide and isoproterenol once, no significant change.Pale complexion when examining, the light red tongue purple, there is indentation on the limit, white and thin fur, slow pulse is tied generation.The electrocardio diagram: heart rate 44 times/minute, restrain uneven.
Take Chinese medicine composition of the present invention after 15 days, consciously painedly subtract the improvement of breathing hard slightly, continue and obeyed Chinese medicine composition of the present invention 20, ambition pain is significantly improved, and attack times obviously reduces, extremity are temperature gradually, and spirit is gradually shaken, and continues and obeys Chinese medicine composition of the present invention 1 month, it is fixed that cardiopalmus becomes, and precordialgia disappears substantially, and symptom is greatly taken on a new look, the check electrocardiogram is normal substantially, obeys Chinese medicine composition of the present invention again 1 month, and symptom all disappears, ambition is happy, has rosy cheeks, and is energetic.
Five, therapeutic outcome:
In the 135 routine cases of being accepted for medical treatment,, wherein cure 88 examples through treatment in 5 months, produce effects 13 examples, effective 27 examples, invalid 7 examples, total effective rate reaches 94%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment angina disease patient.

Claims (4)

1. Chinese medicine composition for the treatment of angina disease, its feature is made by following bulk drugs: Fructus Aurantii Immaturus 100 grams, Rhizoma Chuanxiong 30 grams, Radix Curcumae 30 grams, Olibanum 15 grams, Myrrha 15 grams, Radix Bupleuri 30 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, the Radix Linderae 50 grams, Fructus Toosendan 50 grams, Radix Aristolochiae 40 grams, Pericarpium Arecae 30 grams, Bulbus Allii Macrostemonis 20 grams, Lignum Santali Albi 20 grams, Fructus Citri Sarcodactylis 30 grams, Fructus Citri 30 grams, Aspongopus 10 grams, Cortex Cinnamomi 20 grams, Rhizoma Zingiberis 20 grams, Fructus Evodiae 20 grams, Flos Caryophylli 10 grams, Fructus Foeniculi 10 grams, Rhizoma Alpiniae Officinarum 20 grams, Rhizoma Corydalis 50 grams, Rhizoma Curcumae Longae 50 grams, Radix Et Rhizoma Rhei 50 grams, Radix Salviae Miltiorrhizae 30 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Lignum Sappan 30 grams, Rhizoma Curcumae 15 grams, rhizoma sparganic 15 grams, Squama Manis 10 grams, Moschus 1 gram, Styrax 30 grams, Benzoinum 30 grams, Camphora 10 grams, Borneolum Syntheticum 10 grams, Rhizoma Acori Graminei 50 grams, Radix Codonopsis 30 grams, Radix Angelicae Sinensis 100 grams, the Radix Paeoniae Alba 50 grams, Ramulus Cinnamomi 40 grams, Herba Asari 3 grams, Rhizoma Et Radix Notopterygii 20 grams, Herba Schizonepetae 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Rehmanniae Preparata 40 grams.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that: the method for Chinese medicinal according to routine is prepared into any oral formulations commonly used.
3. according to the described Chinese medicine composition of claim 2, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
4. the application of each described Chinese medicine composition of claim 1~3 in preparation treatment angina disease medicine.
CN2009103099747A 2009-11-19 2009-11-19 Traditional Chinese medicine composition for treating angina disease and preparation method thereof Expired - Fee Related CN101716330B (en)

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