CN101716291B - Oral traditional Chinese medicine for treating skin diseases - Google Patents

Oral traditional Chinese medicine for treating skin diseases Download PDF

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CN101716291B
CN101716291B CN2009102199470A CN200910219947A CN101716291B CN 101716291 B CN101716291 B CN 101716291B CN 2009102199470 A CN2009102199470 A CN 2009102199470A CN 200910219947 A CN200910219947 A CN 200910219947A CN 101716291 B CN101716291 B CN 101716291B
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radix
grams
chinese medicine
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traditional chinese
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CN101716291A (en
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王茂基
王伟
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Abstract

The invention relates to an oral traditional Chinese medicine for treating skin diseases. The oral traditional Chinese medicine is prepared from radix lithospermi, rhizoma smilacis glabrae, fructus gardeniae, cortex dictamni, common peony roots, radix scrophulariae, rehmanniae radix, isatis indigotica forts, radix sophorae flavescentis, lalang grass rhizome, flos sophorae, radix sileris, puncturevine caltrop fruits, red-rooted salvia roots, ligusticum wallichii, large-leaved gentian, processed polygonum multiflorum, Chinese angelica, white paeony roots and licorice roots. The oral traditional Chinese medicine is a pure traditional Chinese medicine prescription, reduces the recurrence rate of psoriasis and obviously improves the cure rate. In the invention, by mixing the Chinese angelica, the white paeony roots, the isatis indigotica forts and the licorice roots for use, the organism immunity can be enhanced greatly and the problem of recurrence of the psoriasis due to cold and pharyngitis can be solved. The oral traditional Chinese medicine has high effective rate to the psoriasis more than 98 percent and also has 100 percent cure rate to conventional skin diseases such as acne, cutaneous pruritus, pityriasis rosea, eczema, lichen planus, neurodermatitis, urticaria, seborrheic dermatitis, and the like.

Description

The dermopathic oral Chinese medicine of a kind of treatment
Technical field
The present invention relates to a kind of medicine, relate to the dermopathic oral Chinese medicine of a kind of treatment specifically.
Background technology
Human epidermal, impaired or owing to external cause such as pruritus, high low temperature variation, high light, radioactivity and chemical substance owing to inner reasons such as blood constituent variation, endocrine disturbance, cause positions such as the hair follicle of skin, big eccrine gland, sebaceous gland to be subjected to the infection of antibacterial, fungus or virus and the various skin disease takes place.The traditional Chinese medical science is then thought by due to seven emotions, eating and drinking without temperance, overstrain, visceral dysfunction, six evil, epidemic disease, the worm etc.
At present, the medicine for external use of treatment dermatosis Western medicine commonly used not only costs an arm and a leg, and mix steroid hormone in medicine, and easily recurrence is easy to generate dependency and Drug resistance after the drug withdrawal, and life-time service produces more side effect to human body.The most treating the poisonous disease with poisonous drugs schemes that adopt of Chinese traditional treatment dermatosis, the drug toxicity consumption is big, and is big to human body harm.Chinese patent medicine can only be treated one or more dermatosiss usually, and therapeutic domain is narrow, and therapeutic effect is not obvious, and especially psoriasis is easily being caught a cold back recurrence, falls ill because of flu during prevention and the control treatment, is present Chinese medicinal formulae institute an open question.
Summary of the invention
At the defective that existing treatment dermatosis treating medicine exists, it is few to the invention provides a kind of dosage, evident in efficacy, and relapse rate is low, is applicable to the oral Chinese medicine of the sick treatment of various skin such as psoriasis, acne, eczema.
Addressing the above problem the concrete measure of being taked is: the dermopathic oral Chinese medicine of a kind of treatment is characterized in that: by mass parts, and Radix Arnebiae (Radix Lithospermi) 10, Rhizoma Smilacis Glabrae 10-20, Fructus Gardeniae 7-8, Cortex Dictamni 7-10, Radix Paeoniae Rubra 7-8, Radix Scrophulariae 7-8, Radix Rehmanniae 8-12, Radix Isatidis 8-12, Radix Sophorae Flavescentis 7-8, Rhizoma Imperatae 7-8, Flos Sophorae 8-12, Radix Saposhnikoviae 7-10, Fructus Tribuli 8-12, Radix Salviae Miltiorrhizae 7-8, Rhizoma Chuanxiong 7-8, Radix Gentianae Macrophyllae 3-7, Radix Polygoni Multiflori Preparata 10-20, Radix Angelicae Sinensis 8-12, Radix Paeoniae Alba 3-7, Radix Glycyrrhizae 7-8.
Best prescription: by mass parts, Radix Arnebiae (Radix Lithospermi) 10, Rhizoma Smilacis Glabrae 15, Fructus Gardeniae 7.5, Cortex Dictamni 7.5, Radix Paeoniae Rubra 7.5, Radix Scrophulariae 7.5, Radix Rehmanniae 10, Radix Isatidis 10, Radix Sophorae Flavescentis 7.5, Rhizoma Imperatae 7.5, Flos Sophorae 10, Radix Saposhnikoviae 7.5, Fructus Tribuli 10, Radix Salviae Miltiorrhizae 7.5, Rhizoma Chuanxiong 7.5, Radix Gentianae Macrophyllae 5, Radix Polygoni Multiflori Preparata 15, Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 5, Radix Glycyrrhizae 7.5.
Most dermatosiss belong to heat symptom-complex, and common pathologic basis is arranged, and eliminate heat symptom-complex, and eliminating blood stasis and killing or suppress microorganism is the principle of organizing medicine.
Medicine name flavor efficacy
Antipyretic:
Radix Arnebiae (Radix Lithospermi) is sweet, and cold and cool blood is invigorated blood circulation
The detoxifcation rash
Rhizoma Smilacis Glabrae is sweet, and is light, the sharp joint of flat detoxifcation dehumidifying
The Cortex Dictamni hardship, cold dispeiling pathogenic wind and removing dampness
Heat-clearing and toxic substances removing
The Radix Sophorae Flavescentis hardship, cold heat clearing and damp drying parasite killing
Radix Rehmanniae is sweet, hardship, cold clearing away heat and cooling blood
YIN nourishing and the production of body fluid promoting
The Radix Isatidis hardship, cold heat-clearing and toxic substances removing removing heat from blood
Sore-throat relieving
The Fructus Gardeniae hardship, diarrhea due to cold pathogen fire relieving restlessness clearing away heat-damp and promoting diuresis
Removing pathogenic heat from blood and toxic substance from the body
The Radix Paeoniae Rubra hardship, the clearing away heat and cooling blood stasis-dispelling and pain-killing is slightly cold
The Radix Scrophulariae hardship, sweet, salty, cold heat-clearing and toxic substances removing yin nourishing
Hemorrhage:
The Flos Sophorae hardship, the clearing away heat and cooling blood that is slightly cold hemostasis
Rhizoma Imperatae is sweet, cold and cool blood hemostasis clearing away heat and promoting diuresis
Diaphoretic medicine:
The Radix Saposhnikoviae suffering, sweet, tepor expelling pathogenic wind from the body surface removing dampness to relieve pain
Liver wind calming drug:
The Fructus Tribuli hardship, suffering, the soothing the liver dispelling pathogenic wind for improving eyesight of average liver
Blood circulation and stasis-eliminating medicine:
The Radix Salviae Miltiorrhizae hardship, blood circulation promoting and blood stasis dispelling removing heat from blood eliminating carbuncle is slightly cold
Nourishing blood to tranquillize the mind
The Rhizoma Chuanxiong suffering, warm blood-activating and qi-promoting wind-expelling pain-stopping
Medicine for rheumatism:
The Radix Gentianae Macrophyllae hardship, suffering, wind-damp dispelling Shujin network clearind deficient heat is slightly cold
Qi-restoratives medicine:
Radix Angelicae Sinensis is sweet, suffering, the intestine moistening of temperature compensation blood promoting blood circulation and stopping pain
Radix Paeoniae Alba hardship, acid, the yin fluid astringing easing the affected liver to relieve pain that nourishes blood is slightly cold
Suppressing liver-YANG
Radix Glycyrrhizae is sweet, flat invigorating the spleen and replenishing QI intestine moistening cough-relieving
Relax property of medicine relieving spasm to stop pain
Radix Polygoni Multiflori Preparata is sweet, and hardship is puckery, the detoxifcation of tepor invigorating the liver and kidney benefiting essence-blood
Loosening bowel to relieve constipation.
The present invention treats dermopathic oral Chinese medicine
Function: heat-clearing and toxic substances removing, dispelling wind for relieving itching, nourshing Yin and drynsessmoistening prescription, removing heat from blood and promoting blood circulation.
Cure mainly: psoriasis, acne, skin pruritus, pityriasis rosea, eczema, lichen planus, neurodermatitis, urticaria, seborrheic dermatitis etc.
The present invention treats dermopathic oral Chinese medicine, makes oral capsule or honeyed pill or decoction according to conventional method.Points for attention: 1. Deficiency and coldness of spleen and stomach, stomachache the loose stool person should not use.
2. the amenorrhea of deficiency and coldness is avoided usefulness.
3. the period in a medicine and the diet Fructus Capsici within back three months of healing, wine, Carnis Gallus domesticus fish, seafood.
Untoward reaction: still indeterminate.
Criterion of therapeutical effect: select the sickness rate height, the dermatosis that cure rate is low is the case among the embodiment, and by following criterion of therapeutical effect examination.
Psoriasis:
Total mark * 100% before therapeutic index=(total mark before the treatment-treatment back total mark) ÷ treatment
Cure: therapeutic index is more than or equal to 90%
Produce effects: therapeutic index 60%-89%
Progressive: therapeutic index 20%-59%
Invalid: therapeutic index is less than 20%
Pityriasis rosea:
Cure: skin lesion disappears fully
Produce effects: skin lesion disappears more than 2/3
Effectively: skin lesion disappears more than 1/3, below 2/3
Invalid: skin lesion disappears below 1/3
Acne:
Cure: erythra all disappears, and does not have new rash and takes place, local anti-residual only a few skin lesion (cicatrix)
Produce effects: erythra is dwindled, and skin lesion is disappeared more than 70%
Effectively: skin lesion disappear more than 30% or inflammation obviously alleviate
Invalid: erythra is seen slightly and is alleviated, or no change, or more originally increases the weight of
Eczema:
Cure: skin lesion recovers normal, does not itch, or slight gargalesthesia is arranged
Produce effects: 70% skin lesion recovers normal, and remaining skin lesion gradually takes a turn for the better, with slight pruritus
Take a turn for the better: 30% skin lesion recovers normal, and remaining skin lesion has plumpness or few liquid to ooze out, and with scratchiness, but still can stand
Invalid: local skin lesion is less than the improvement standard, or do not have improvement, even worsens
Dermatitis:
Cure: erythra disappears fully, and subjective symptoms disappears
Produce effects: deflorescence is more than 70%, and subjective symptoms is obviously improved
Take a turn for the better: deflorescence is below 70%, and more than 30%, subjective symptoms takes a turn for the better to some extent
Invalid: erythra and subjective symptoms all do not have obvious improvement, and be basic with before the treatment
Beneficial effect of the present invention: the present invention is pure Chinese medicine preparation, has reduced the psoriasis relapse rate, and cure rate is obviously improved.Wherein, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Isatidis, Radix Glycyrrhizae compatibility use, and can obviously increase body immunity, have solved the difficult problem that psoriasis recurs because of flu, pharyngitis.We remove the psoriasis effective percentage are reached better curative effect more than 98%, also can reach 100% to cure rates such as common skin diseases such as acne, skin pruritus, pityriasis rosea, eczema, lichen planus, neurodermatitis, urticaria, seborrheic dermatitis.
The specific embodiment
Embodiment 1:
Radix Arnebiae (Radix Lithospermi) 10 grams, Rhizoma Smilacis Glabrae 10-20 gram, Fructus Gardeniae 7-8 gram, Cortex Dictamni 7-10 gram, Radix Paeoniae Rubra 7-8 gram, Radix Scrophulariae 7-8 gram, Radix Rehmanniae 8-12 gram, Radix Isatidis 8-12 gram, Radix Sophorae Flavescentis 7-8 gram, Rhizoma Imperatae 7-8 gram, Flos Sophorae 8-12 gram, Radix Saposhnikoviae 7-10 gram, Fructus Tribuli 8-12 gram, Radix Salviae Miltiorrhizae 7-8 gram, Rhizoma Chuanxiong 7-8 gram, Radix Gentianae Macrophyllae 3-7 gram, Radix Polygoni Multiflori Preparata 10-20 gram, Radix Angelicae Sinensis 8-12 gram, Radix Paeoniae Alba 3-7 gram, Radix Glycyrrhizae 7-8 gram.
According to the conditions of patients of seing patients, open the decoction prescription by above-mentioned prescription scope, every dose of dose 215 grams, fried according to a conventional method one-tenth decoction is obeyed twice every day.
Below be that inventor king's cyclopentadienyl, Wang Wei investigate 1980-1988 357 routine psoriasis curative effects in Manchu Autonomous County of Kuandian institute of traditional Chinese medicine.
Clinical types: homeliness type erythrodermic pustule type arthrosis type
Case load: 346 911
The medical history classification: 2-3 4-5 was more than 6 years in<1 year
Case load: 167 139 34 17
The curative effect investigation:
Medicine time: 30 days 40 days 60 days 70 days 90 days 120 days
Produce effects case: 0 132 112 94 87 84
Progressive case: 324 176 91 63 29 2
Invalid case: 33 26 19 13 92
Cure case: 0 23 135 187 232 269
Above-mentioned invalid case is outer meson gas ointment and a large amount of hormones wiped, due to the medicines such as oral aminopterin.
Embodiment 2:
Radix Arnebiae (Radix Lithospermi) 10 grams, Rhizoma Smilacis Glabrae 15 grams, Fructus Gardeniae 7 grams, Cortex Dictamni 9 grams, Radix Paeoniae Rubra 8 grams, Radix Scrophulariae 7 grams, Radix Rehmanniae 10 grams, Radix Isatidis 12 grams, Radix Sophorae Flavescentis 7 grams, Rhizoma Imperatae 8 grams, Flos Sophorae 10 grams, Radix Saposhnikoviae 9 grams, Fructus Tribuli 10 grams, Radix Salviae Miltiorrhizae 8 grams, Rhizoma Chuanxiong 7 grams, Radix Gentianae Macrophyllae 5 grams, Radix Polygoni Multiflori Preparata 15 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 5 grams, Radix Glycyrrhizae 7 grams.
Make honeyed pill by above-mentioned prescription with conventional method, 9 gram honeyed pill content are 4.2 grams, each 1 ball, and 3 times on the 1st are oral.
It below is routine curing psoriasis investigation in 1989-1998 854.
Clinical types: homeliness type erythrodermic pustule type arthrosis type
Case load: 842 723
The medical history classification: 2-3 4-5 6-7 was more than 8 years in<1 year
Case load: 617 131 54 29 23
The curative effect investigation:
Medicine time: 30 days 60 days 90 days 120 days 150 days
Produce effects case: 0 157 452 217 128
Recovery from illness case: 00 149 522 716
Effective case: 136 474 138 72 6
Invalid case: 718 223 115 43 4
Below be 1989-1998 1028 routine cases of acne investigation.
The medical history classification: 2-3 4-5 was more than 6 years in<one year
Case load: 452 484 61 31
The curative effect investigation:
Medicine time: 20 days 30 days 40 days 60 days 80 days
Produce effects case: 0 639 383 134 0
Cure case: 0 72 500 845 1028
Effective case: 752 243 118 49 0
Invalid case: 276 74 27 00
It below is routine eczema case curative effect investigation in 1989-1998 1195.
Clinical types: acute eczema subacute eczema chronic eczema
Case load: 587 423 185
The medical history classification: 2-3 4-5 was more than 6 years in<1 year
Case load: 687 465 43 5
The curative effect investigation:
Period in a medicine: 20 days 30 days 40 days 60 days 90 days
Cure case: 0 56 375 812 1195
Produce effects case: 69 387 502 260 0
Improvement case: 431 489 276 123 0
Invalid case: 695 263 42 00
It below is routine pityriasis rosea case curative effect investigation in 1989-1998 323.
Medical history classification: within half a year
The curative effect investigation:
Medicine time: 30 days 40 days 60 days 90 days
Produce effects case: 124 109 88 0
Recovery from illness case: 0 118 211 323
Effective case: 110 85 24 0
Invalid case: 89 11 00
Embodiment 3:
Radix Arnebiae (Radix Lithospermi) 10 grams, Rhizoma Smilacis Glabrae 15 grams, Fructus Gardeniae 7.5 grams, Cortex Dictamni 7.5 grams, Radix Paeoniae Rubra 7.5 grams, Radix Scrophulariae 7.5 grams, Radix Rehmanniae 10 grams, Radix Isatidis 10 grams, Radix Sophorae Flavescentis 7.5 grams, Rhizoma Imperatae 7.5 grams, Flos Sophorae 10 grams, Radix Saposhnikoviae 7.5 grams, Fructus Tribuli 10 grams, Radix Salviae Miltiorrhizae 7.5 grams, Rhizoma Chuanxiong 7.5 grams, Radix Gentianae Macrophyllae 5 grams, Radix Polygoni Multiflori Preparata 15 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 5 grams, Radix Glycyrrhizae 7.5 grams.
Make capsule according to a conventional method, every contains 0.3 gram, takes the 4-5 grain at every turn, and 3 times on the 1st oral, and 60 days is a course of treatment.
It below is routine psoriasis curative effect investigation in 1999-2008 1343.
Clinical types: homeliness type erythrodermic pustule type arthrosis type
Case load: 736 245 12 16
The medical history classification: 2-3 4-5 6-7 was more than 8 years in<1 year
Case load: 873 216 202 31 21
The curative effect investigation:
Medicine time: 12 months October of 8 month June of 4 month February
Produce effects case: 0 416 451 394 119 76
Recovery from illness case: 00 397 814 1,163 1250
Progressive case: 429 611 382 93 43 7
Invalid case: 914 316 113 42 18 10
It below is routine cases of acne curative effect investigation in 1999-2008 1009.
The medical history classification: 2-3 4-5 is more than 6 years within 1 year
Case load: 636 245 97 31
The curative effect investigation:
Medicine time: 20 days 30 days 40 days 60 days 80 days
Produce effects case: 0 488 363 128 0
Recovery from illness case: 0 75 507 836 1009
Effective case: 675 374 116 45 0
Invalid case: 334 72 23 00
Embodiment 4:
Radix Arnebiae (Radix Lithospermi) 10 grams, Rhizoma Smilacis Glabrae 30 grams, Fructus Gardeniae 10 grams, Cortex Dictamni 15 grams, Radix Paeoniae Rubra 10 grams, Radix Scrophulariae 10 grams, Radix Rehmanniae 15 grams, Radix Isatidis 10 grams, Radix Sophorae Flavescentis 10 grams, Rhizoma Imperatae 15 grams, Flos Sophorae 10 grams, Radix Saposhnikoviae 15 grams, Fructus Tribuli 10 grams, Radix Salviae Miltiorrhizae 10 grams, Rhizoma Chuanxiong 10 grams, Radix Gentianae Macrophyllae 5 grams, Radix Polygoni Multiflori Preparata 10 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 10 grams, Radix Glycyrrhizae 10 grams.
Make capsule routinely, every 0.3 gram is taken the 4-5 grain at every turn, and 3 times on the 1st oral, and 60 days is a course of treatment.
It below is routine eczema case curative effect investigation in 1999-2008 1541.
Clinical types: acute eczema, subacute eczema, chronic eczema
The medical history classification: 2-3 4-5 was more than 6 years in 1 year
Case load: 985 487 53 16
The curative effect investigation:
Medicine time: 20 days 30 days 40 days 60 days 90 days 120 days
Produce effects case: 66 381 485 491 13 0
Recovery from illness case: 0 61 400 870 1,528 1541
Improvement case: 713 792 577 159 00
Invalid case: 762 307 79 21 00
Below be 1999-2008 264 routine pityriasis rosea case curative effect investigation.
Medical history classification: within half a year
The curative effect investigation:
Medicine time: 30 days 40 days 60 days 90 days
Produce effects case: 74 138 67 0
Recovery from illness case: 0 69 188 264
Effective case: 151 48 90
Invalid case: 39 900
Embodiment 5:
Radix Arnebiae (Radix Lithospermi) 10 gram Rhizoma Smilacis Glabraes 35 grams, Fructus Gardeniae 10 grams, Cortex Dictamni 10 grams, Radix Paeoniae Rubra 15 grams, Radix Scrophulariae 15 grams, Radix Rehmanniae 15 grams, Radix Isatidis 10 grams, Radix Sophorae Flavescentis 10 grams, Rhizoma Imperatae 20 grams, Flos Sophorae 10 grams, Radix Saposhnikoviae 10 grams, Fructus Tribuli 10 grams, Radix Salviae Miltiorrhizae 10 grams, Rhizoma Chuanxiong 10 grams, Radix Gentianae Macrophyllae 5 grams, Radix Polygoni Multiflori Preparata 10 grams, Radix Angelicae Sinensis 10 grams, the Radix Paeoniae Alba 10 grams, Radix Glycyrrhizae 10 grams.
Make capsule according to a conventional method, every contains 0.3 gram, takes the 4-5 grain at every turn, and 3 times on the 1st, 20 days is a course of treatment.
It below is routine dermatitis case curative effect investigation in 1999-2008 3625.
Medical history classification: 1 month 2 months 3 months 6 months 1 year 2-3
Case load: 212 1,054 672 1,248 415 24
The curative effect investigation:
Medicine time: 20 days 30 days 40 days 60 days 90 days
Recovery from illness case: 365 1,038 1,994 2,957 3625
Produce effects case: 913 1,155 1,095 590 0
Improvement case: 1,001 1,001 507 78 0
Invalid case: 1,346 431 29 00
Comprehensive embodiment 1~5 can find out:
Psoriasis: total case load 2554 example recovery from illness case loads 2235 routine cure rates 87.51%
Produce effects case load 288 routine total effective rates 98.78%
Acne: total case load 2037 example recovery from illness case loads 2037 routine cure rates 100%
Pityriasis rosea: total case load 587 example recovery from illness case loads 587 routine cure rates 100%
Eczema: total case load 2736 example recovery from illness case loads 2736 routine cure rates 100%
Dermatitis: total case load 3625 example recovery from illness case loads 3625 routine cure rates 100%
Relapse rate: carry out follow-up investigation in 1~3 year, relapse rate 0% to curing case.

Claims (2)

1. treat dermopathic oral Chinese medicine for one kind, it is characterized in that: by mass parts, Radix Arnebiae (Radix Lithospermi) 10, Rhizoma Smilacis Glabrae 10~20, Fructus Gardeniae 7~8, Cortex Dictamni 7~10, Radix Paeoniae Rubra 7~8, Radix Scrophulariae 7~8, Radix Rehmanniae 8~12, Radix Isatidis 8~12, Radix Sophorae Flavescentis 7~8, Rhizoma Imperatae 7~8, Flos Sophorae 8~12, Radix Saposhnikoviae 7~10, Fructus Tribuli 8~12, Radix Salviae Miltiorrhizae 7~8, Rhizoma Chuanxiong 7~8, Radix Gentianae Macrophyllae 3~7, Radix Polygoni Multiflori Preparata 10~20, Radix Angelicae Sinensis 8~12, the Radix Paeoniae Alba 3~7, Radix Glycyrrhizae 7~8.
2. the dermopathic oral Chinese medicine of a kind of treatment according to claim 1 is characterized in that: by mass parts, and Radix Arnebiae (Radix Lithospermi) 10, Rhizoma Smilacis Glabrae 15, Fructus Gardeniae 7.5, Cortex Dictamni 7.5, Radix Paeoniae Rubra 7.5, Radix Scrophulariae 7.5, Radix Rehmanniae 10, Radix Isatidis 10, Radix Sophorae Flavescentis 7.5, Rhizoma Imperatae 7.5, Flos Sophorae 10, Radix Saposhnikoviae 7.5, Fructus Tribuli 10, Radix Salviae Miltiorrhizae 7.5, Rhizoma Chuanxiong 7.5, Radix Gentianae Macrophyllae 5, Radix Polygoni Multiflori Preparata 15, Radix Angelicae Sinensis 10, the Radix Paeoniae Alba 5, Radix Glycyrrhizae 7.5.
CN2009102199470A 2009-11-17 2009-11-17 Oral traditional Chinese medicine for treating skin diseases Expired - Fee Related CN101716291B (en)

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