CN101695514B - Traditional Chinese medicinal preparation for treating trauma and cicatricial hyperplasia gargalesthesia and preparation method thereof - Google Patents
Traditional Chinese medicinal preparation for treating trauma and cicatricial hyperplasia gargalesthesia and preparation method thereof Download PDFInfo
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- CN101695514B CN101695514B CN2009100758278A CN200910075827A CN101695514B CN 101695514 B CN101695514 B CN 101695514B CN 2009100758278 A CN2009100758278 A CN 2009100758278A CN 200910075827 A CN200910075827 A CN 200910075827A CN 101695514 B CN101695514 B CN 101695514B
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Abstract
The invention relates to a traditional Chinese medicinal preparation for treating trauma and cicatricial hyperplasia gargalesthesia and a preparation method thereof and belongs to the technical field of medicaments. The medicament is used for solving the problem of treating skin trauma and particularly burn cicatricial hyperplasia gargalesthesia. The invention adopts technical scheme that: the medicament comprises the following raw material medicaments: 50 to 200 grams of argy wormwood leaf, 30 to 200 grams of safflower, 5 to 10 grams of camphore and 200 ml of alcohol of 75 percent. The preparation method comprises the following steps of: decocting the argy wormwood leaf; infusing the safflower and the camphore with the alcohol respectively; and then mixing all the liquid medicine. The medicament is based on the theory of traditional Chinese medicament and years of clinical experience formulas, has the effects of boosting qi and engendering liquid, nourishing blood and moistening dryness, promoting qi and liquid, issuing dryness and relieving itching and is combined with effects of softening hardness and dissipating binds, quickening blood and transforming stasis, and dispersing swelling and relieving pain. The medicament can effectively inhibit scar gargalesthesia, can inhibit the scar forming and promotes recovery of skin function on the scar at the same time. The medicament has the characteristics of simple formula, low price, quick response and the like. The effective rate of clinical observation reaches over 95 percent.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method, after the wound such as particularly can effectively suppress to burn scar hyperplasia and gargalesthesia with Chinese medicine preparation and preparation method, belong to medical technical field.
Background technology
The hypertrophy cicatrix that skin produced after wound was particularly burnt can have a strong impact on the attractive in appearance of skin, and cicatrix will be in case formation will be followed patient's all one's life, generally eliminate cicatrix and need pass through operative treatment, this not only brings the misery of a new round to the patient, and increases the weight of patient's financial burden.The hypertrophy cicatrix is many with serious gargalesthesia, influence to the patient mainly contains the following aspects: 1. the scratching that serious gargalesthesia does not stop the patient, and the slight damage that can cause the cicatrix place to take place repeatedly, thus cause the serious hypertrophy of cicatrix, the secondary caused by scar has only the operative treatment of passing through; 2. continuing violent gargalesthesia can produce serious harmful effect to patient's psychology and physiology, as causes insomnia, depressed, spirit depressing etc., and the normal work and study of patient are interfered.The treatment cicatrix antipruritic agent weak effect of clinical practice at present, cost an arm and a leg, and need the external long period, compliance is poor, and increases the weight of patient economy burden.
Summary of the invention
Technical problem to be solved by this invention is: provide a kind of safe and convenient to use, antipruritic effect good, the Chinese medicine preparation and the preparation method of cheap treatment trauma and cicatricial hyperplasia gargalesthesia.
Alleged problem of the present invention is solved by following technical scheme:
A kind of Chinese medicine preparation for the treatment of trauma and cicatricial hyperplasia gargalesthesia, its special feature is that it is made up of following raw material medicaments: Folium Artemisiae Argyi 50 grams-200 grams, Flos Carthami 30 grams-200 grams, Camphora 5-10 gram, 200 milliliters of 75% ethanol.
The preparation method of the Chinese medicine preparation of above-mentioned treatment trauma and cicatricial hyperplasia gargalesthesia, it carries out as follows:
A. Folium Artemisiae Argyi 30-120 minute of usefulness 500-1000 ml water immersion formula ratio, the temperature fire boiled 30 minutes, and to aseptic bottle, surplus medicine adds water 500-1000 milliliter and boiled once more 30 minutes-120 minutes with medicinal liquid, after the medicinal liquid that boils for twice mixed, it was standby to be concentrated into the 100-150 milliliter;
B. get 100 milliliters of 75% ethanol, the Flos Carthami of formula ratio is immersed in the ethanol 30 minutes-120 minutes, alcohol-pickled liquid is standby to the aseptic bottle;
C. get 100 milliliters of 75% ethanol, the Camphora of formula ratio is dissolved in the ethanol;
D. with the medicinal liquid mix homogeneously of above-mentioned a, b, c step, promptly make medicament of the present invention.
Medicament of the present invention is based on theory of Chinese medical science and clinical experience prescription for many years, traditional Chinese medical science viewpoint thinks that the cicatrix pathogenesis comprises: 1. gas loses the deficiency of YIN, the dry muscular contracture of blood, promptly be secondary to after the burn due to hot liquid or fire, skin holostrome and deep tissue reach to the whole body qi-blood-body fluid so are depleted, be difficult to the physiological function of recovering original, qi-blood-body fluid access denial, muscle muscle arteries and veins can not get moistening of qi-blood-body fluid and support and cause cicatrization; 2. meridians numbness resistance, i.e. after the space between skin and muscles skin damage, meridians are obstructed, and battalion defends imbalance, and stagnation of QI congestion forms.At cicatrization mechanism, this drug prescription has supplementing QI for promoting the production of body fluid, the blood enriching and dryness moistening effect, cause tachypnea Jin Wang and dry go out to itch end, in conjunction with hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, when effectively suppressing the cicatrix gargalesthesia, suppress cicatrization, promote the recovery of cicatrix place skin function.This medicament has characteristics such as prescription is simple, cheap, and onset is rapid, and the clinical observation effective percentage reaches more than 95%.
The specific embodiment
Traditional Chinese medical science viewpoint thinks that cicatrix is many hinders or burn due to hot liquid or fire because of golden cutter, and residual poison is unclean, invaded due to the skin by exopathogen.Main pathogenesis comprises 1, gas loses the deficiency of YIN, the dry muscular contracture of blood, promptly be secondary to after the burn due to hot liquid or fire, skin holostrome and deep tissue reach to the whole body qi-blood-body fluid so are depleted, after the recovery from illness, skin and deep tissue are difficult to the physiological function of recovering original, and qi-blood-body fluid is directly burnt because of burning hot heresy on the one hand and lost in the body; Because of the damage of skin and deep tissue, qi-blood-body fluid access denial, muscle muscle arteries and veins can not get the foster cicatrization that causes of moistening of qi-blood-body fluid on the other hand; 2, the resistance of meridians numbness.After being the damage of space between skin and muscles skin, meridians are obstructed, and battalion defends imbalance, and stagnation of QI congestion forms.The treatment by Chinese herbs of cicatrix comprises the reinforcement supplementing QI for promoting the production of body fluid, blood enriching and dryness moistening, cause tachypnea Jin Wang and dry go out to itch end, in conjunction with hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.The present invention in conjunction with the achievement in research of clinical cicatrix mechanism, has proposed inhibition scar hyperplasia and itching relieving Chinese medicine preparation on the empirical basis of inheriting tradition.The said preparation main component comprises Folium Artemisiae Argyi, Flos Carthami and Camphora.Wherein, Folium Artemisiae Argyi: another name Radix Artemisia ordosicae, XIANGAI, the dried leaves of feverfew Chinese mugwort, major function: dehumidifying parasite killing, antalgesic-antipruritic; Flos Carthami: annual herb plant, major function: the latus rectum of invigorating blood circulation, eliminating stasis to stop pain; Camphora: the another name Camphora, the tree brain, solid constituent in the Lignum cinnamomi camphorae volatile oil, major function: it is antipruritic to invigorate blood circulation, faint anticorrosion.Three kinds of medicines are that main blood enriching and dryness moistening alleviates gargalesthesia with Folium Artemisiae Argyi and Camphora, are aided with the Flos Carthami activating blood circulation to dissipate blood stasis, promoting flow of QI and blood, and dredging the meridian, thus suppress and alleviate scar hyperplasia.
Several embodiment below are provided:
Embodiment 1: take by weighing Folium Artemisiae Argyi 30 grams, and Flos Carthami 50 grams, Camphora 5 grams are got 200 milliliters of 75% ethanol.Folium Artemisiae Argyi is immersed in 500 ml waters 60 minutes, and warm fire boiled 30 minutes, and to aseptic bottle, surplus medicine adds 500 milliliters in water and boiled once more 30 minutes with medicinal liquid, after the medicinal liquid that boils for twice is mixed, be concentrated into 100 milliliters standby; Get 100 milliliters of 75% ethanol, Flos Carthami is immersed in the ethanol 30 minutes, alcohol-pickled liquid is standby to the aseptic bottle; Getting 100 milliliters of Camphoras with formula ratio of 75% ethanol is dissolved in the ethanol; With above-mentioned three kinds of medicinal liquid mix homogeneously, make medicament of the present invention.
Embodiment 2: take by weighing Folium Artemisiae Argyi 100 grams, and Flos Carthami 30 grams, Camphora 10 grams are got 200 milliliters of 75% ethanol.Folium Artemisiae Argyi is immersed in 800 ml waters 30, and warm fire boiled 60 minutes, and to aseptic bottle, surplus medicine adds 700 milliliters in water and boiled once more 60 minutes with medicinal liquid, after the medicinal liquid that boils for twice is mixed, be concentrated into 120 milliliters standby; Get 100 milliliters of 75% ethanol, Flos Carthami is immersed in the ethanol 60 minutes, alcohol-pickled liquid is standby to the aseptic bottle; Getting 100 milliliters of 75% ethanol is dissolved into Camphora in the ethanol; With above-mentioned three kinds of medicinal liquid mix homogeneously, make medicament of the present invention.
Embodiment 3: take by weighing Folium Artemisiae Argyi 200 grams, and Flos Carthami 200 grams, Camphora 10 grams are got 200 milliliters of 75% ethanol.Folium Artemisiae Argyi is immersed in 1000 ml waters 120 minutes, and warm fire boiled 120 minutes, and to aseptic bottle, surplus medicine adds 1000 milliliters in water and boiled once more 60 minutes with medicinal liquid, be concentrated into after the medicinal liquid that boils for twice is mixed 150 milliliters standby; Get 100 milliliters of 75% ethanol Flos Carthami is immersed in the ethanol 120 minutes, alcohol-pickled liquid is standby to the aseptic bottle; Getting 100 milliliters of Camphoras with formula ratio of 75% ethanol is dissolved in the ethanol; With above-mentioned three kinds of medicinal liquid mix homogeneously, make medicament of the present invention.
Embodiment 4: take by weighing Folium Artemisiae Argyi 120 grams, and Flos Carthami 80 grams, Camphora 7 grams are got 200 milliliters of 75% ethanol.Folium Artemisiae Argyi is immersed in 900 ml waters 100 minutes, and warm fire boiled 100 minutes, and to aseptic bottle, surplus medicine adds 600 milliliters in water and boiled once more 40 minutes with medicinal liquid, be concentrated into after the medicinal liquid that boils for twice is mixed 130 milliliters standby; Get 100 milliliters of 75% ethanol Flos Carthami is immersed in the ethanol 120 minutes, alcohol-pickled liquid is standby to the aseptic bottle; Getting 100 milliliters of Camphoras with formula ratio of 75% ethanol is dissolved in the ethanol; With above-mentioned three kinds of medicinal liquid mix homogeneously, make medicament of the present invention.
Medicament of the present invention is a medicine for external use, picks with cotton swab during use that a small amount of medicine is directly outer to be applied on the cicatrix with obvious gargalesthesia, every day three to five times, after treatment week age again after gargalesthesia disappears.Medicament clinical observation of the present invention, effective percentage reaches more than 95%.
Below enumerating concrete case further specifies the effective percentage of this medicine:
Patient's situation sees Table 1.
Numbering | Sex | Age | The cicatrization reason | Application site |
01 (field) | The man | 27 | The slag burn | Behind the both hands wound healing |
02 (Lee) | The woman | 45 | Flame burn | Both hands are behind the abdomen back of the body wound healing |
03 (tremble certain) | The man | 10 | Avulsion injury of skin | Right lower limb skin-grafting area and skin donor site |
04 (Zhang) | The man | 22 | The hydrothermal solution burn | Left upper extremity wound healing zone |
05 (Lee) | The woman | 24 | Flame burn | Right upper extremity wound healing zone |
Various cicatrix degree scorings see Table 2
Cicatrix degree classification integration standard (beauty and shaping surgery, Song Ruyao, the clear woods chief editor in side, third edition P291)
Getting the foregoing description medicament is medicine for external use, picks with cotton swab during use that a small amount of medicine is directly outer to be applied on the cicatrix with obvious gargalesthesia, every day three to five times, after gargalesthesia disappears after treatment 5-10 days again.
The result
Five routine patients through application behind these medicines gargalesthesia one week the back obviously improve, adhere to after medication January that gargalesthesia obviously alleviates or disappears effective percentage 95%.The cicatrix degree obtains improvement in various degree, the results are shown in following table.
Numbering | Application site | Cicatrix scoring before using | After using for 1 week | After using January | Effect |
01 (field) | Behind the both hands wound healing | 12 | 7 | 5 | Obviously |
02 (Lee) | Both hands are behind the abdomen back of the body wound healing | 14 | 11 | 7 | Obviously |
03 (tremble certain) | Right lower limb skin-grafting area and skin donor site | 8 | 6 | 4 | Obviously |
04 (Zhang) | Left upper extremity wound healing zone | 14 | 10 | 8 | Obviously |
05 (Lee) | Right upper extremity wound healing zone | 10 | 8 | 6 | Obviously |
Claims (2)
1. a Chinese medicine preparation for the treatment of trauma and cicatricial hyperplasia gargalesthesia is characterized in that it is made up of following raw material medicaments: Chinese mugwort
Leaf 50 grams-200 grams, Flos Carthami 30 grams-200 grams, Camphora 5-10 gram, 200 milliliters of 75% ethanol.
2. the preparation method of treatment trauma and cicatricial hyperplasia gargalesthesia Chinese medicine preparation according to claim 1 is characterized in that, it carries out as follows:
A. Folium Artemisiae Argyi 30-120 minute of usefulness 500-1000 ml water immersion formula ratio, the temperature fire boiled 30 minutes, and to aseptic bottle, surplus medicine adds water 500-1000 milliliter and boiled once more 30 minutes-120 minutes with medicinal liquid, after the medicinal liquid that boils for twice mixed, it was standby to be concentrated into the 100-150 milliliter;
B. get 100 milliliters of 75% ethanol, the Flos Carthami of formula ratio is immersed in the ethanol 30 minutes-120 minutes, alcohol-pickled liquid is standby to the aseptic bottle;
C. get 100 milliliters of 75% ethanol, the Camphora of formula ratio is dissolved in the ethanol;
D. with the medicinal liquid mix homogeneously of above-mentioned a, b, c step.
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1355040A (en) * | 2000-12-01 | 2002-06-26 | 李性钠 | Exterior-applied medicine for treating beriberi and tinea pedis and its preparing process |
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CN1355040A (en) * | 2000-12-01 | 2002-06-26 | 李性钠 | Exterior-applied medicine for treating beriberi and tinea pedis and its preparing process |
Non-Patent Citations (3)
Title |
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姜琳.艾叶巧治皮肤病.《健康天地》.2002, * |
梅全喜等.艾叶化学及药理研究进展.《中成药》.2006,第28卷(第7期),1030. * |
程桃英等.复方樟脑止痒擦剂的制备及临床应用.《中国医院药学杂志》.2002,381. * |
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