CN101692902A - Food compositions for lowering and releasing uric acid and preventing gout - Google Patents

Food compositions for lowering and releasing uric acid and preventing gout Download PDF

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Publication number
CN101692902A
CN101692902A CN200910018636A CN200910018636A CN101692902A CN 101692902 A CN101692902 A CN 101692902A CN 200910018636 A CN200910018636 A CN 200910018636A CN 200910018636 A CN200910018636 A CN 200910018636A CN 101692902 A CN101692902 A CN 101692902A
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China
Prior art keywords
uric acid
gout
chitin
food compositions
dietary fiber
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CN200910018636A
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Chinese (zh)
Inventor
李桂玲
李泽瑶
李钰金
邵鹏
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TAIXIANG GROUP TECHNOLOGY DEVELOPMENT Co Ltd
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TAIXIANG GROUP TECHNOLOGY DEVELOPMENT Co Ltd
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Priority to CN200910018636A priority Critical patent/CN101692902A/en
Publication of CN101692902A publication Critical patent/CN101692902A/en
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to a food composition containing chitin for lowering and releasing uric acid and preventing gout, which comprises the following components in percentage by weight: 70-95% of chitin dietary fiber, 5-30% of yam powder, 0-3% of taurine and 0-3% of arginine. The food composition of the invention is provided with non-toxic side effects, is safe to eat, can prevent purine, fat and cholesterol from absorbing, restrain uric acid from forming and provide better effects of boosting kidney, keeping healthy, improving uric acid discharge and preventing gout.

Description

A kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout
Technical field
The present invention relates to a kind of preparation that contains chitosan, especially a kind ofly include the falling of chitin, releasing uric acid and prevent and treat the food compositions of gout.
Background technology
Gout (Gout) is that the purine of human body gets muddled in synthetic and decomposable process, makes the synthetic increase of uric acid or gets rid of minimizing, accumulates the hyperuricemia that causes in vivo.When the blood uric acid excessive concentration, uric acid promptly is deposited in joint, soft tissue, cartilage and the kidney with the form of sodium salt, causes the foreign matter inflammatory reaction of tissue.Show that according to Chinese disease in 2004 and health survey center analysis report China hyperuricemia patient number reaches 1.2 hundred million at present, its patient with gout surpasses 7,500 ten thousand people, and just increases with annual 0.97% annual growth.Gout is actual to be a kind of and the closely-related metabolic disease of life, mainly be because modern's living standard improves, in the process of indulging oneself in eating and drinking, unconsciously taken in too much and the relevant high purine diet of gout morbidity, and cause the generation of gout, promptly gout is a kind of rich man's disease that eats.
At present, adopt Western medicine to treat patient with gout in the symptom selectivity that different times showed clinically.Used medicine mainly contains three classes: 1, promote the medicine of uric acid excretion, and as Benzbromarone, probenecid, sulfinpyrazone etc.; 2, suppress the medicine that uric acid generates, as allopurinol (unique application clinically); 3, easing pain and diminishing inflammation class medicine is as colchicin, non-steroid anti-inflammatory drug, glucocorticoid indocin, Phenylbutazone class, brufen class, feldene, prednisone, dexamethasone etc.But said medicine can only be used for mitigate the disease, takes said medicine for a long time and can produce toxic and side effect to human liver, kidney.
The Chinese medicine gout can be carried out dialectical treatment according to different etiology and pathogenesis.For example on August 29th, 2007 Granted publication CN100333758C Chinese invention patent specification in disclosed " a kind of composition and method of making the same of antigout Chinese medicine ", on November 14th, 2007 Granted publication CN100348248C Chinese invention patent specification in disclosed " a kind of Chinese medicine composition and preparation method who treats gout ", on October 15th, 2008 Granted publication CN100425268C Chinese invention patent specification in disclosed " a kind of medicine for the treatment of gout ", on August 26th, 2009 Granted publication CN100531769C Chinese invention patent specification in disclosed " a kind of Chinese medicine composition for the treatment of gout and preparation method thereof ", disclosed CN101347605A Chinese invention patent ublic specification of application on January 21st, 2009 disclosed " a kind of Chinese medicine composition that is used for the treatment of gout and its production and use ", in on April 8th, the 2009 disclosed CN101401865A Chinese invention patent ublic specification of application disclosed " a kind of Chinese medicine composition for the treatment of gout ", in on September 2nd, the 2009 disclosed CN101518630A Chinese invention patent ublic specification of application disclosed " Chinese medicine composition of a kind of antigout and preparation method thereof ", disclosedly in the above-mentioned open file be used for the treatment of the Chinese medicine composition or the decoction of gout or the clothes or make tablet or make capsule of steeping in wine, in addition can carry out dialectical treatment gout.But, as the saying goes " being three fens poison of medicine ", the herbal component that it adopted all can produce toxic and side effect to human body.
Prevention and treatment gout will at first be controlled the various common diseases that cause gout, the generation of frequently-occurring disease, and 1, guarantee the normal of human body purine metabolism; 2, reduce uric acid in the body generation, accumulate; 3, strengthen renal function, it is unobstructed that uric acid is discharged.
" integration of drinking and medicinal herbs " is the method for preventing and curing diseases that Ancient Times in China passes on the tool distinct Chinese characteristics.Therefore work hard from diet, taking food therapy fundamentally to prevent and treat gout is an effective way.
Chitin is being collectively referred to as of chitin and spherical chitosan (a few butylamine candy).Chitin (chitin) is a kind of Nantural non-toxic macromolecule with spherical chitosan (chitosan), and has Biodegradable, its structure similar plants cellulose, by 1000-3000 N-second gucosamine (N-Acety12-Amino-2Deoxy-d-DGlucose or n-Acetyl-d-Glucosamine) monomer with B-1, the straight chain shape macromolecule carbohydrate that 4 keys are constituted.Do not have toxicity and can be decomposed by organism, biologically active is regarded as the boiomacromolecule of potentialization, should be called as the chitin dietary fiber.Chitin is a kind of edible fibers element, experimental results show that there being the knurl mouse to take through chitin (chitosan): it is the function safety food of a kind of immunoactivator, rare integration of drinking and medicinal herbs, can be dissolved in acid gastric juice, therefore easily is absorbed by the body.It is same class material with usual edible starch, is both polysaccharide, and different is that chitin derives from animal, and starch source is in plant, and it does not have toxic and side effect, has the expert to point out, its security even be higher than white sugar.At present, chitin is applied to prevents and treats in the gout, only seeing on January 16th, 2008 disclosed CN1011103994A Chinese invention patent ublic specification of application had report in disclosed " medicine of a kind of prevention and treatment gout and hyperuricemia ".
Summary of the invention
For overcome Chinese herbal medicine in the prior art, Western medicine is prevented and treated gout, its drug ingedient can produce the deficiency of toxic and side effect to human body, the invention provides a kind of prevention purine, fat, cholesterol absorption, suppressing uric acid generates, body-strengthening and lung-invigorating functions promotes the falling of uric acid excretion, releasing uric acid and prevents and treats the food compositions of gout.
The technical solution adopted for the present invention to solve the technical problems is: a kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, it is characterized in that: the component that it comprises and the percentage by weight of each component are respectively: chitin dietary fiber 70-95%, yam flour 5-30%, taurine 0-3%, arginine 0-3%.
Describedly a kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, the component that it comprises and the percentage by weight of each component are respectively: chitin dietary fiber 89.9%, yam flour 10%, taurine 0.05%, arginine 0.05%.
The chitin fiber element that described chitin dietary fiber is produced for the crab shell, its deacetylation are more than 80%.
The present invention falls, releasing uric acid and the food compositions of preventing and treating gout with the chitin dietary fiber as primary raw material, its to reduce, promote drain uric acid and prevent and treat gout the mechanism of action as follows:
1, crust have the activation immune cell, the propagation of booster immunization cell, and the effect that improves body's immunity can promote the new life and the normalization of liver, kidney damaged cell, protection hepatic and renal function.
2, chitin is the high molecular polymer that is not absorbed by the body, and is gel state after entering human body, can form the absorption that a skim stoped fattiness, sugar in alimentary canal.Chitin is added in the food and also can be adhered on it owing to the ion absorption makes food by human body, do not cause food by the human body taken in excess, thereby the generation of the hypertension that can suppress the absorption of overfeeding and cause, high fat of blood, hyperglycemia, reduce purine, suppress uric acid and generate, and then reduce the generation of gout.
3, chitin occurs with the cation form of positively charged in vivo, can combine with cholic acid and cholate, thereby can suppress the absorption of small intestine to cholesterol, not only can reduce the accumulating amount of cholesterol at liver, therefore also can reduce low density cholesterol, increasing high density cholesterol, hard and cardiovascular and cerebrovascular disease and gout have good effect to prevention of arterial.
4, chitin is the food fiber of unique positively charged (the cationic charge NH3+) that exist in the present universe, can by itself with positive electricity cation and food in electronegative fat adhere to automatically and combine, absorb in the blocking-up fat-body, reduce the generation of purine, suppress uric acid and generate, reduce the generation of gout.
5, the chitin dietary fiber is that alkalescence shows dietary fiber, can improve body inner acidic environment, and people's body fluid (mainly being blood) is maintained in the healthy alkalescence state (PH Zhi Approximately As 7.3 to 7.5) all the time; Also can improve simultaneously the sour environment of urine, suppress the uric acid that the acid-base value problem because of uric acid concentration in the urine and uric acid causes and the generation of lithangiuria, and then reduce the generation of gout.
The present invention falls, releasing uric acid and prevent and treat another primary raw material yam flour of the food compositions of gout, it contains amounts of protein, various vitamin and beneficial trace elements, carbohydrate, it can regulate the human immune system, strengthen body immunity, be that national regulation can be the material that medicine can be food again, be called as " food medicine ".Because of it is rich in arginine, amylase, iodine, calcium, phosphorus and vitamin C etc., the effect of the benefit essence of strengtheninging the spleen and tonifying the lung, reinforce the kidney is arranged, be brain tonic, the good merchantable brand that makes eye bright.To insufficiency of vital energy and blood, weakness of the spleen and the stomach grade causes lustreless complexion, and therapeutic action is all arranged, and therefore, this nutraceutical can effectively solve the treatment problem of gout, also helps to strengthen simultaneously human body constitution.
The present invention falls, releasing uric acid and prevent and treat arginine that the food compositions of gout the adds carrier as the body metabolism biotic factor, can induce, stimulate adrenergic generation, relaxes the generation that reduces blood sugar and reduce aliphatic acid; Can increase the activity of arginase in the liver, help to change the ammonia in the blood into urea and excrete out, and have the function of the immunity of antifatigue, enhancing human body; The taurine of its interpolation should have the effect of the strong body that reinforces the kidney, and can improve renal function, helps excreting of uric acid.
Food compositions of the present invention has no side effect, and edible safety can stop purine, fat, cholesterol absorption, suppresses uric acid and generates, and body-strengthening and lung-invigorating functions promotes uric acid excretion, and it is effective to prevent and treat gout.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, the percentage by weight of its component and each component is: chitin dietary fiber 89.9%, yam flour 10%, taurine 0.05%, arginine 0.05%.The chitin fiber element that this chitin dietary fiber is produced for the crab shell, its deacetylation is more than 90%.
The food compositions that present embodiment goes out can add the glidant dolomol in right amount and prepare capsule product.
During preparation particle capsule, above-mentioned material component is mixed through the micronizer pulverizing, pulverizing the back particle is 80 orders, goes into the comminutor granulation after batch mixer fully mixes again.The mixed liquor that adds 40% second alcohol and water in the granulation process; Again with boiling drier oven dry water content 4-6%, polish then, bottling forms to regulation.
Embodiment 2
A kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, the percentage by weight of its component and each component is: chitin dietary fiber 70%, yam flour 29%, taurine 1%.The chitin fiber element that this chitin dietary fiber is produced for the shrimp shell, its deacetylation is more than 80%.
The food compositions that present embodiment goes out can be used as the additive of food, according to the diseases prevention of " integration of drinking and medicinal herbs ", the method for curing the disease, works hard from diet, takes that food therapy is fundamentally fallen, releasing uric acid and prevent and treat gout.
Embodiment 3
A kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, the percentage by weight of its component and each component is: chitin dietary fiber 80%, yam flour 15%, taurine 2.5%, arginase 12 .5%.The chitin fiber element that this chitin dietary fiber is produced for the sea crab shell, its deacetylation is more than 95%.
The food compositions that present embodiment goes out can add excipients in right amount and be pressed into tablet.
Embodiment 4
A kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, the percentage by weight of its component and each component is: chitin dietary fiber 94%, yam flour 5.95%, taurine 0.03%, arginine 0.02%.The chitin fiber element that this chitin dietary fiber is produced for the river crab shell, its deacetylation is more than 90%.
The composition that present embodiment goes out can be ground into powder (40-100 order); enteric or the molten coating material of stomach are adopted in granulation in the fluidized drying granulator, carry out spray coating under fluidized state in the equipment of spray coating; wrap one deck coatings at least equably, make coated granule.
Embodiment 5
A kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, the percentage by weight of its component and each component is: chitin dietary fiber 75%, yam flour 24.5%, arginine 0.5%.The chitin fiber element that this chitin dietary fiber is produced for the pond crayfish shell, its deacetylation is more than 85%.
The composition that present embodiment goes out can be used as the additive of food, according to the diseases prevention of " integration of drinking and medicinal herbs ", the method for curing the disease, works hard from diet, takes that food therapy is fundamentally fallen, releasing uric acid and prevent and treat gout.
Embodiment 6
A kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, the percentage by weight of its component and each component is: chitin dietary fiber 85%, yam flour 14.85%, taurine 0.08%, arginine 0.07%.The chitin fiber element that this chitin dietary fiber is produced for the sea crab shell, its deacetylation is more than 95%.
The composition that present embodiment goes out can be ground into powder 70 orders, and granulation in multi-functional granulator with the boiling drier oven dry, is made granule.

Claims (3)

  1. One kind fall, releasing uric acid and prevent and treat the food compositions of gout, it is characterized in that: the component that it comprises and the percentage by weight of each component are respectively: chitin dietary fiber 70-95%, yam flour 5-30%, taurine 0-3%, arginine 0-3%.
  2. 2. according to claim 1ly a kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, it is characterized in that: the component that it comprises and the percentage by weight of each component are respectively: chitin dietary fiber 89.9%, yam flour 10%, taurine 0.05%, arginine 0.05%.
  3. 3. according to claim 1 and 2ly a kind ofly fall, releasing uric acid and prevent and treat the food compositions of gout, it is characterized in that: the chitin fiber element that described chitin dietary fiber is produced for the crab shell, its deacetylation are more than 80%.
CN200910018636A 2009-09-05 2009-09-05 Food compositions for lowering and releasing uric acid and preventing gout Pending CN101692902A (en)

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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102077933A (en) * 2010-09-20 2011-06-01 王强 Special dietary seafood special for hyperuricemia patients
CN102511808A (en) * 2011-12-26 2012-06-27 北京福佑龙惠生物科技开发有限公司 Arginine natural vegetable and fruit powder and preparation method thereof
CN112914060A (en) * 2021-03-29 2021-06-08 吉林农业大学 Food prepared from radix adenophorae, Chinese yam and lotus root and having effects of protecting liver and kidney and relieving gout

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102077933A (en) * 2010-09-20 2011-06-01 王强 Special dietary seafood special for hyperuricemia patients
CN102077933B (en) * 2010-09-20 2013-04-24 王强 Special dietary seafood special for hyperuricemia patients
CN102511808A (en) * 2011-12-26 2012-06-27 北京福佑龙惠生物科技开发有限公司 Arginine natural vegetable and fruit powder and preparation method thereof
CN112914060A (en) * 2021-03-29 2021-06-08 吉林农业大学 Food prepared from radix adenophorae, Chinese yam and lotus root and having effects of protecting liver and kidney and relieving gout

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Open date: 20100414