CN101672834A - Method for detecting quality of Chinese medicinal preparation for treating diabetic retinopathy - Google Patents
Method for detecting quality of Chinese medicinal preparation for treating diabetic retinopathy Download PDFInfo
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- CN101672834A CN101672834A CN 200810183368 CN200810183368A CN101672834A CN 101672834 A CN101672834 A CN 101672834A CN 200810183368 CN200810183368 CN 200810183368 CN 200810183368 A CN200810183368 A CN 200810183368A CN 101672834 A CN101672834 A CN 101672834A
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- methyl alcohol
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- ethanol
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- 238000002360 preparation method Methods 0.000 title claims abstract description 54
- 238000000034 method Methods 0.000 title claims abstract description 39
- 206010012689 Diabetic retinopathy Diseases 0.000 title claims abstract description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 134
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 125
- 239000000463 material Substances 0.000 claims abstract description 47
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims abstract description 39
- RXUWDKBZZLIASQ-UHFFFAOYSA-N Puerarin Natural products OCC1OC(Oc2c(O)cc(O)c3C(=O)C(=COc23)c4ccc(O)cc4)C(O)C(O)C1O RXUWDKBZZLIASQ-UHFFFAOYSA-N 0.000 claims abstract description 25
- HKEAFJYKMMKDOR-VPRICQMDSA-N puerarin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=CC(C2=O)=C1OC=C2C1=CC=C(O)C=C1 HKEAFJYKMMKDOR-VPRICQMDSA-N 0.000 claims abstract description 25
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims abstract description 18
- 241000405414 Rehmannia Species 0.000 claims abstract description 13
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 12
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 12
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 11
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 11
- 238000005251 capillar electrophoresis Methods 0.000 claims abstract description 11
- 239000009636 Huang Qi Substances 0.000 claims abstract description 6
- 238000001914 filtration Methods 0.000 claims abstract description 6
- 239000000243 solution Substances 0.000 claims description 172
- 238000012360 testing method Methods 0.000 claims description 112
- 239000013558 reference substance Substances 0.000 claims description 59
- 239000000284 extract Substances 0.000 claims description 38
- 239000000047 product Substances 0.000 claims description 35
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 34
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 30
- 239000000706 filtrate Substances 0.000 claims description 24
- 239000003795 chemical substances by application Substances 0.000 claims description 20
- 238000004587 chromatography analysis Methods 0.000 claims description 20
- 239000000741 silica gel Substances 0.000 claims description 20
- 229910002027 silica gel Inorganic materials 0.000 claims description 20
- 239000003480 eluent Substances 0.000 claims description 16
- 239000000825 pharmaceutical preparation Substances 0.000 claims description 16
- 239000007787 solid Substances 0.000 claims description 16
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 14
- 239000003814 drug Substances 0.000 claims description 14
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 12
- 244000241872 Lycium chinense Species 0.000 claims description 11
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 10
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 10
- 239000007921 spray Substances 0.000 claims description 10
- 238000005303 weighing Methods 0.000 claims description 10
- 241000545744 Hirudinea Species 0.000 claims description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 8
- 238000010992 reflux Methods 0.000 claims description 8
- 229910021529 ammonia Inorganic materials 0.000 claims description 7
- SIHHLZPXQLFPMC-UHFFFAOYSA-N chloroform;methanol;hydrate Chemical compound O.OC.ClC(Cl)Cl SIHHLZPXQLFPMC-UHFFFAOYSA-N 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 239000011347 resin Substances 0.000 claims description 7
- 229920005989 resin Polymers 0.000 claims description 7
- 239000012085 test solution Substances 0.000 claims description 7
- 238000003556 assay Methods 0.000 claims description 6
- 238000010828 elution Methods 0.000 claims description 6
- 238000009472 formulation Methods 0.000 claims description 6
- 230000007935 neutral effect Effects 0.000 claims description 6
- ZRSNZINYAWTAHE-UHFFFAOYSA-N p-methoxybenzaldehyde Chemical compound COC1=CC=C(C=O)C=C1 ZRSNZINYAWTAHE-UHFFFAOYSA-N 0.000 claims description 6
- 238000002137 ultrasound extraction Methods 0.000 claims description 6
- YEZWWUMWIFKEQM-UHFFFAOYSA-N O.OC.ClC(Cl)Cl.CCOC(C)=O Chemical compound O.OC.ClC(Cl)Cl.CCOC(C)=O YEZWWUMWIFKEQM-UHFFFAOYSA-N 0.000 claims description 5
- DLUOMMXONAIKQD-UHFFFAOYSA-N OC=O.ClC(Cl)Cl.CCOC(C)=O Chemical compound OC=O.ClC(Cl)Cl.CCOC(C)=O DLUOMMXONAIKQD-UHFFFAOYSA-N 0.000 claims description 5
- 235000008331 Pinus X rigitaeda Nutrition 0.000 claims description 5
- 235000011613 Pinus brutia Nutrition 0.000 claims description 5
- 241000018646 Pinus brutia Species 0.000 claims description 5
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 5
- CZCSLHYZEQSUNV-UHFFFAOYSA-N [Na].OB(O)O Chemical compound [Na].OB(O)O CZCSLHYZEQSUNV-UHFFFAOYSA-N 0.000 claims description 5
- QMNWISYXSJWHRY-YLNUDOOFSA-N astragaloside IV Chemical compound O1[C@H](C(C)(O)C)CC[C@]1(C)[C@@H]1[C@@]2(C)CC[C@]34C[C@]4(CC[C@H](O[C@H]4[C@@H]([C@@H](O)[C@H](O)CO4)O)C4(C)C)[C@H]4[C@@H](O[C@H]4[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O4)O)C[C@H]3[C@]2(C)C[C@@H]1O QMNWISYXSJWHRY-YLNUDOOFSA-N 0.000 claims description 5
- QMNWISYXSJWHRY-BCBPIKMJSA-N astragaloside IV Natural products CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]2[C@@H](O)C[C@@]3(C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@H](O)[C@@H](O)[C@H]5O)[C@H]6C(C)(C)[C@H](CC[C@@]67C[C@@]47CC[C@]23C)O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O QMNWISYXSJWHRY-BCBPIKMJSA-N 0.000 claims description 5
- 229910021538 borax Inorganic materials 0.000 claims description 5
- 239000000872 buffer Substances 0.000 claims description 5
- 239000007853 buffer solution Substances 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- PFKIBRPYVNVMRU-UHFFFAOYSA-N cyclosieversioside F Natural products CC(C)(O)C1COC(C)(C1)C2C(O)CC3(C)C4CC(OC5OC(CO)C(O)C(O)C5O)C6C(C)(C)C(CCC67CC47CCC23C)OC8OCC(O)C(O)C8O PFKIBRPYVNVMRU-UHFFFAOYSA-N 0.000 claims description 5
- 238000001514 detection method Methods 0.000 claims description 5
- 239000000945 filler Substances 0.000 claims description 5
- BDAGIHXWWSANSR-UHFFFAOYSA-N formic acid Substances OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 5
- 239000012982 microporous membrane Substances 0.000 claims description 5
- YTJSFYQNRXLOIC-UHFFFAOYSA-N octadecylsilane Chemical compound CCCCCCCCCCCCCCCCCC[SiH3] YTJSFYQNRXLOIC-UHFFFAOYSA-N 0.000 claims description 5
- 238000007254 oxidation reaction Methods 0.000 claims description 5
- 229910052700 potassium Inorganic materials 0.000 claims description 5
- 239000011591 potassium Substances 0.000 claims description 5
- 239000013643 reference control Substances 0.000 claims description 5
- 238000000926 separation method Methods 0.000 claims description 5
- 239000000377 silicon dioxide Substances 0.000 claims description 5
- 239000004328 sodium tetraborate Substances 0.000 claims description 5
- 239000006228 supernatant Substances 0.000 claims description 5
- 244000046146 Pueraria lobata Species 0.000 claims description 4
- 235000010575 Pueraria lobata Nutrition 0.000 claims description 4
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 4
- 239000000469 ethanolic extract Substances 0.000 claims description 4
- 238000011003 system suitability test Methods 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 3
- 239000011780 sodium chloride Substances 0.000 claims description 3
- 101800000263 Acidic protein Proteins 0.000 claims description 2
- QIIDATRCGITYRZ-UHFFFAOYSA-N Catalpol Natural products OCC1OC(OC2OC=CC3C(O)C(=C(CO)C23)O)C(O)C(O)C1O QIIDATRCGITYRZ-UHFFFAOYSA-N 0.000 claims description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- 101710093543 Probable non-specific lipid-transfer protein Proteins 0.000 claims description 2
- 240000001398 Typha domingensis Species 0.000 claims description 2
- 239000003957 anion exchange resin Substances 0.000 claims description 2
- LHDWRKICQLTVDL-PZYDOOQISA-N catalpol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@@H]2[C@@]3(CO)O[C@H]3[C@@H](O)[C@@H]2C=CO1 LHDWRKICQLTVDL-PZYDOOQISA-N 0.000 claims description 2
- UXSACQOOWZMGSE-UHFFFAOYSA-N catalposide Natural products OC1C(O)C(O)C(CO)OC1OC1C2C3(CO)OC3C(OC(=O)C=3C=CC(O)=CC=3)C2C=CO1 UXSACQOOWZMGSE-UHFFFAOYSA-N 0.000 claims description 2
- HXOLFXRMWWHLMH-UHFFFAOYSA-L disodium boric acid carbonate Chemical compound [Na+].[Na+].OB(O)O.[O-]C([O-])=O HXOLFXRMWWHLMH-UHFFFAOYSA-L 0.000 claims description 2
- 239000000796 flavoring agent Substances 0.000 claims description 2
- 235000013905 glycine and its sodium salt Nutrition 0.000 claims description 2
- IXCSERBJSXMMFS-UHFFFAOYSA-N hcl hcl Chemical compound Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 claims description 2
- JWHHANVGNNWIRI-UHFFFAOYSA-N methanol phosphoric acid hydrate Chemical compound O.OC.OP(O)(O)=O JWHHANVGNNWIRI-UHFFFAOYSA-N 0.000 claims description 2
- LHDWRKICQLTVDL-UHFFFAOYSA-N methyl iridoid glycoside Natural products OC1C(O)C(O)C(CO)OC1OC1C2C3(CO)OC3C(O)C2C=CO1 LHDWRKICQLTVDL-UHFFFAOYSA-N 0.000 claims description 2
- 108090000623 proteins and genes Proteins 0.000 claims description 2
- 102000004169 proteins and genes Human genes 0.000 claims description 2
- 210000000582 semen Anatomy 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- ZEFCBWQRHWLUTC-UHFFFAOYSA-M sodium;2,3-dihydroxybutanedioic acid;2,3,4-trihydroxy-4-oxobutanoate Chemical compound [Na+].OC(=O)C(O)C(O)C(O)=O.OC(=O)C(O)C(O)C([O-])=O ZEFCBWQRHWLUTC-UHFFFAOYSA-M 0.000 claims description 2
- FYKDNWHPKQOZOT-UHFFFAOYSA-M sodium;dihydrogen phosphate;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Na+].OP(O)([O-])=O.OC(=O)CC(O)(C(O)=O)CC(O)=O FYKDNWHPKQOZOT-UHFFFAOYSA-M 0.000 claims description 2
- 239000001117 sulphuric acid Substances 0.000 claims description 2
- 235000011149 sulphuric acid Nutrition 0.000 claims description 2
- 238000004811 liquid chromatography Methods 0.000 claims 2
- 239000012141 concentrate Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 238000000605 extraction Methods 0.000 abstract description 14
- 238000004128 high performance liquid chromatography Methods 0.000 abstract description 3
- 244000241838 Lycium barbarum Species 0.000 abstract 1
- 235000015459 Lycium barbarum Nutrition 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000002203 pretreatment Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 description 31
- 239000000523 sample Substances 0.000 description 29
- 210000004185 liver Anatomy 0.000 description 7
- 239000002904 solvent Substances 0.000 description 7
- 150000001875 compounds Chemical class 0.000 description 6
- 210000003734 kidney Anatomy 0.000 description 6
- 239000012488 sample solution Substances 0.000 description 5
- 241000201295 Euphrasia Species 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 230000035922 thirst Effects 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 230000002040 relaxant effect Effects 0.000 description 2
- 238000013112 stability test Methods 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 241000219780 Pueraria Species 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN200810183368.0A CN101672834B (en) | 2008-12-01 | 2008-12-01 | Method for detecting quality of Chinese medicinal preparation for treating diabetic retinopathy |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200810183368.0A CN101672834B (en) | 2008-12-01 | 2008-12-01 | Method for detecting quality of Chinese medicinal preparation for treating diabetic retinopathy |
Publications (2)
Publication Number | Publication Date |
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CN101672834A true CN101672834A (en) | 2010-03-17 |
CN101672834B CN101672834B (en) | 2014-08-13 |
Family
ID=42020151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN200810183368.0A Active CN101672834B (en) | 2008-12-01 | 2008-12-01 | Method for detecting quality of Chinese medicinal preparation for treating diabetic retinopathy |
Country Status (1)
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CN (1) | CN101672834B (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104807948A (en) * | 2015-05-11 | 2015-07-29 | 中国人民解放军第三七一医院 | Quality control method for anti-vertigo granules |
CN104940219A (en) * | 2015-06-01 | 2015-09-30 | 哈尔滨医科大学 | Chinese medicinal composition for diabetic retinopathy simple stage treatment and preparation method thereof |
CN105675791A (en) * | 2016-02-05 | 2016-06-15 | 四川德成动物保健品有限公司 | Antipyretic-and-antitoxic-powder pretreatment method for detecting rehmannia in thin-layer chromatography mode |
CN105699585A (en) * | 2016-02-05 | 2016-06-22 | 四川德成动物保健品有限公司 | Test method for radix rehmanniae in scourge-clearing toxin-vanquishing powder |
CN112020738A (en) * | 2018-04-23 | 2020-12-01 | 陈浩能 | Method and apparatus for product monitoring |
CN112255324A (en) * | 2020-08-31 | 2021-01-22 | 广州泽力医药科技有限公司 | Method for establishing fingerprint of wolfberry fruit and kudzu vine root solid beverage and fingerprint thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100345569C (en) * | 2005-03-17 | 2007-10-31 | 河北以岭医药研究院有限公司 | Medicine for treating glycuresis retinal disease and its prepn. method |
-
2008
- 2008-12-01 CN CN200810183368.0A patent/CN101672834B/en active Active
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104807948A (en) * | 2015-05-11 | 2015-07-29 | 中国人民解放军第三七一医院 | Quality control method for anti-vertigo granules |
CN104940219A (en) * | 2015-06-01 | 2015-09-30 | 哈尔滨医科大学 | Chinese medicinal composition for diabetic retinopathy simple stage treatment and preparation method thereof |
CN105675791A (en) * | 2016-02-05 | 2016-06-15 | 四川德成动物保健品有限公司 | Antipyretic-and-antitoxic-powder pretreatment method for detecting rehmannia in thin-layer chromatography mode |
CN105699585A (en) * | 2016-02-05 | 2016-06-22 | 四川德成动物保健品有限公司 | Test method for radix rehmanniae in scourge-clearing toxin-vanquishing powder |
CN112020738A (en) * | 2018-04-23 | 2020-12-01 | 陈浩能 | Method and apparatus for product monitoring |
CN112255324A (en) * | 2020-08-31 | 2021-01-22 | 广州泽力医药科技有限公司 | Method for establishing fingerprint of wolfberry fruit and kudzu vine root solid beverage and fingerprint thereof |
CN112255324B (en) * | 2020-08-31 | 2022-11-29 | 广州泽力医药科技有限公司 | Method for establishing fingerprint of wolfberry fruit and kudzuvine root solid beverage and fingerprint thereof |
Also Published As
Publication number | Publication date |
---|---|
CN101672834B (en) | 2014-08-13 |
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