CN101669958A - 二膦酸类化合物的药物应用 - Google Patents

二膦酸类化合物的药物应用 Download PDF

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Publication number
CN101669958A
CN101669958A CN200910161293A CN200910161293A CN101669958A CN 101669958 A CN101669958 A CN 101669958A CN 200910161293 A CN200910161293 A CN 200910161293A CN 200910161293 A CN200910161293 A CN 200910161293A CN 101669958 A CN101669958 A CN 101669958A
Authority
CN
China
Prior art keywords
cells
letrozole
apoptosis
zol
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200910161293A
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English (en)
Chinese (zh)
Inventor
R·E·科尔曼
I·赫伦
H·内维尔-韦布
C·A·埃万斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Sheffield
Original Assignee
University of Sheffield
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Sheffield filed Critical University of Sheffield
Publication of CN101669958A publication Critical patent/CN101669958A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN200910161293A 2003-12-03 2004-12-02 二膦酸类化合物的药物应用 Pending CN101669958A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0328040.1A GB0328040D0 (en) 2003-12-03 2003-12-03 Pharmaceutical uses of bisphosphonates
GB0328040.1 2003-12-03

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800360730A Division CN1889962A (zh) 2003-12-03 2004-12-02 二膦酸类化合物的药物应用

Publications (1)

Publication Number Publication Date
CN101669958A true CN101669958A (zh) 2010-03-17

Family

ID=29764511

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200910161293A Pending CN101669958A (zh) 2003-12-03 2004-12-02 二膦酸类化合物的药物应用
CNA2004800360730A Pending CN1889962A (zh) 2003-12-03 2004-12-02 二膦酸类化合物的药物应用

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2004800360730A Pending CN1889962A (zh) 2003-12-03 2004-12-02 二膦酸类化合物的药物应用

Country Status (11)

Country Link
US (1) US20070219115A1 (https=)
EP (1) EP1691816A2 (https=)
JP (1) JP2007513118A (https=)
KR (1) KR20060130052A (https=)
CN (2) CN101669958A (https=)
AU (1) AU2004294713B2 (https=)
BR (1) BRPI0417218A (https=)
CA (1) CA2546782A1 (https=)
GB (1) GB0328040D0 (https=)
RU (1) RU2006123423A (https=)
WO (1) WO2005053709A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2332636B1 (es) * 2008-08-06 2011-02-10 Universitat De Les Illes Balears Composicion de liquido de dialisis.
WO2011133687A2 (en) * 2010-04-20 2011-10-27 President And Fellows Of Harvard College Methods and compositions for inhibition of beta2-adrenergic receptor degradation
CN102961785A (zh) * 2012-11-09 2013-03-13 于秀淳 一种用于治疗骨巨细胞瘤的瘤腔填充物及其制备方法
AU2018445164B2 (en) 2018-10-11 2025-05-29 Vifor (International) Ltd. Inositol phosphates for the treatment of ectopic calcification

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK288365B6 (sk) * 1999-02-10 2016-07-01 Astrazeneca Ab Medziprodukty pre chinazolínové deriváty ako inhibítory angiogenézy
BR0213410A (pt) * 2001-10-19 2004-11-03 Novartis Ag Usos farmacêuticos de bisfosfonatos
AU2003250190A1 (en) * 2002-07-30 2004-02-23 Novartis Ag Combination of an aromatase inhibitor with a bisphosphonate

Also Published As

Publication number Publication date
BRPI0417218A (pt) 2007-02-21
EP1691816A2 (en) 2006-08-23
WO2005053709A2 (en) 2005-06-16
WO2005053709A3 (en) 2006-01-05
US20070219115A1 (en) 2007-09-20
AU2004294713A1 (en) 2005-06-16
RU2006123423A (ru) 2008-01-20
CA2546782A1 (en) 2005-06-16
AU2004294713B2 (en) 2009-04-30
CN1889962A (zh) 2007-01-03
JP2007513118A (ja) 2007-05-24
KR20060130052A (ko) 2006-12-18
GB0328040D0 (en) 2004-01-07

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Open date: 20100317