CN101632697A - Medicinal composition, application thereof and shoe pad product thereof - Google Patents
Medicinal composition, application thereof and shoe pad product thereof Download PDFInfo
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- CN101632697A CN101632697A CN200810133292A CN200810133292A CN101632697A CN 101632697 A CN101632697 A CN 101632697A CN 200810133292 A CN200810133292 A CN 200810133292A CN 200810133292 A CN200810133292 A CN 200810133292A CN 101632697 A CN101632697 A CN 101632697A
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Abstract
The invention provides a medicinal composition. The medicinal composition comprises the raw materials of pyrola, asarum, parsnip, Szechuan lovage rhizome and dahurian angelica root. Based on the 100 weight portions of pyrola, the content of the asarum is 20 to 500 portions, the parsnip accounts for 20 to 500 portions, the Szechuan lovage rhizome accounts for 20 to 500 portions, and the dahurian angelica root accounts for 20 to 500 portions. The invention also provides application of the medicinal composition in preparing a medicament for preventing or treating foot diseases. The invention also provides a shoe pad product. The medicinal composition provided by the invention has a health care effect on human feet, can regulate and strength physiological functions of main and collateral channels of the human body, and correct a yin-yang imbalance state so as to effectively prevent or treat the foot diseases such as foot hyperhidrosis, secretory function decay of foot sweat gland and heel pain.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition and application thereof and shoe pad product.
Background technology
Along with China's rapid economy development, the people's living standard is greatly improved, and people not only are satisfied with and resolve adequate food and clothing, but wishes healthyly, reduces disease.It has often been said that " leg-aging before aging, ill foot is pain earlier." people's foot has countless teleneurons, the blood capillary around the teleneuron closely links to each other with brain.Foot apart from heart farthest, the position is minimum, occurs traditional medicine said " qi depression to blood stasis " easily, foot afflictions such as foot hyperhidrosis, the hypofunction of sweaty foot glandular secretion and heel pain for example occur, the people wants health at first will protect foot thus.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition that can effectively prevent or treat foot affliction.
Another object of the present invention provides the application of described pharmaceutical composition.
Another purpose of the present invention provides a kind of shoe pad product.
The invention provides a kind of pharmaceutical composition, wherein, this pharmaceutical composition contains following raw material: Ungula Cervi, Herba Asari, Radix Saposhnikoviae, Rhizoma Chuanxiong and the Radix Angelicae Dahuricae, wherein, with respect to the Ungula Cervi of 100 weight portions, the content of Herba Asari is the 20-500 weight portion, and the content of Radix Saposhnikoviae is the 20-500 weight portion, the content of Rhizoma Chuanxiong is the 20-500 weight portion, and the content of the Radix Angelicae Dahuricae is the 20-500 weight portion.
The present invention also provides pharmaceutical composition of the present invention to be used for preventing or treating the application of the medicine of foot affliction in preparation.
The present invention also provides a kind of shoe pad product, and wherein, this shoe pad product comprises the pharmaceutical composition of the present invention of shoe pad main body and treatment effective dose, and described pharmaceutical composition is filled in the described shoe pad main body and/or loads on the described shoe pad main body.
Pharmaceutical composition provided by the invention can play a role in health care to people foot, make the physiological function of each big meridians of the person obtain adjusting and strengthening, the yin and yang imbalance state obtains correcting, thereby effectively prevent or treat foot affliction, as foot hyperhidrosis, the hypofunction of sweaty foot glandular secretion and heel pain.
The specific embodiment
The pharmaceutical composition that the invention provides contains following raw material: Ungula Cervi, Herba Asari, Radix Saposhnikoviae, Rhizoma Chuanxiong and the Radix Angelicae Dahuricae.
Wherein, with respect to the Ungula Cervi of 100 weight portions, the content of Herba Asari can be the 20-500 weight portion, is preferably the 50-200 weight portion; The content of Radix Saposhnikoviae can be the 20-500 weight portion, is preferably the 50-200 weight portion; The content of Rhizoma Chuanxiong can be the 20-500 weight portion, is preferably the 50-200 weight portion; The content of the Radix Angelicae Dahuricae can be the 20-500 weight portion, is preferably the 50-200 weight portion.
Described Ungula Cervi can be the hoof of various animal in deer family, is preferably the hoof of Cervus nippon Temminck (Cervus nipponTemminck) and/or Cervus elaphus linnaeus (C.elaphus L.).Can on market, buy the Ungula Cervi that has cooked and be used for the present invention, also can obtain, for example can clean up and unhairing, dry and grind and make then by Ungula Cervi with health by the concocting method of routine.The temperature of described oven dry can be 80-150 ℃, is preferably 100-120 ℃.
Herba Asari (Asarum) as the raw material of pharmaceutical composition of the present invention can be root and/or the stem of Aristolochiaceae asarum plant.
Radix Saposhnikoviae as the raw material of pharmaceutical composition of the present invention can be umbelliferae Saposhnikovia divaricata (Saposhnikovia divaricata Turcz.) Schischk.) root.
Rhizoma Chuanxiong as the raw material of pharmaceutical composition of the present invention can be samphire Rhizoma Chuanxiong (Ligusticum chuanxiong Hort.) rhizome.
The Radix Angelicae Dahuricae as the raw material of pharmaceutical composition of the present invention can be the root of the samphire Radix Angelicae Dahuricae (A.dahurica (Fisch.) Benth.et Hook).
Above-mentioned various raw material can be bought the product that has cooked on market, also can obtain by the concocting method of routine, for example can make with grinding by raw material being carried out drying.Exsiccant method can or be dried naturally for oven dry, is preferably nature and dries.Abrasive method can be the Ginding process of field of Chinese medicines routine, and it is the 80-150 order that the condition optimization of grinding makes the particle mean size of described raw material.
This pharmaceutical composition can also contain Alumen, and with respect to the Ungula Cervi of 100 weight portions, the content of Alumen can be the 10-500 weight portion, is preferably the 20-200 weight portion.
Pharmaceutical composition of the present invention can make by described various raw materials are mixed.As long as blended condition makes various raw material mix homogeneously.
Pharmaceutical composition provided by the present invention has the function of blood circulation promoting and blood stasis dispelling, can quicken foot's blood circulation, and the temperature of rising foot is improved the excitement of nerveous system; Can reduce muscle tone in addition, the foot that alleviates after lower limb acutely move is ached, and therefore can be used for preparing the medicine that is used to prevent or treat foot affliction.
Described foot affliction can be selected from one or more in foot hyperhidrosis, the hypofunction of sweaty foot glandular secretion and the heel pain.
The foot hyperhidrosis can cause foot vesicle, erosion, special foot odor, also be easy to suffer from the beriberi bacterial infection, or the disturbance of blood circulation of cold invasion and attack in winter foot causes cold injury, edema local tissue necrosis etc.
The hypofunction of sweaty foot glandular secretion is mainly in the old people, can cause xerosis cutis, suffers from the hemorrhage or pain of feet rhagades easily, the serious foot made localization pyogenic infection etc.
Traditional medicine thinks that mostly blood stored in the liver, main muscle, the smart main bone of kidney, heel pain are because of caused by liver and kidney deficiency, and essence and blood consume muscles and bones is lost to make moist to nourish and added that the evil invasion and attack of rheumatism wound causes the passages through which vital energy circulates impatency, and QI and blood stagnates and has the pass.
The described medicine that is used to prevent or treats foot affliction can be various dosage forms, for example can be powder, paster, suspension.
Can be preferably local topical administration according to the dosage form selection suitable route of administration of medicine, for example paster can be attached to the affected part, can also use suspension (preferred water suspension) foot bath.
Shoe pad product provided by the invention comprises the pharmaceutical composition of the present invention of shoe pad main body and treatment effective dose, and described pharmaceutical composition is filled in the described shoe pad main body and/or loads on the described shoe pad main body.
Described treatment effective dose is meant that the amount of described pharmaceutical composition is enough to play the effect that prevents and/or treats foot affliction.Described foot affliction can be selected from one or more in foot hyperhidrosis, the hypofunction of sweaty foot glandular secretion and the heel pain.Under the preferable case, described pharmaceutical composition accounts for the 1-15 weight % of shoe pad main body, is preferably 2-8 weight %.
Described shoe pad main body can be identical with the shoe pad of various routines.
In pharmaceutical composition being filled in described shoe pad main body and/or loading on the described shoe pad main body, shoe pad of the present invention can adopt conventional method preparation, can be in the process of preparation shoe pad main body the charge compositions, also can be after making the shoe pad main body carrying medicament compositions.Under the preferable case, the preparation method of shoe pad of the present invention comprises mixes glutinous rice flour and pharmaceutical composition with water, heats 5-30 minute down at 100 ℃, makes paste; Paste is coated in the cloth that is used to make the shoe pad main body, makes shoe pad then.The weight ratio of pharmaceutical composition, glutinous rice flour and water can be 1: 0.5-5: 1-10.
Below by embodiment the present invention is described in more detail.
Embodiment 1
This embodiment is used to prepare pharmaceutical composition provided by the invention.
The Cervus nippon Temminck hoof of health is cleaned up and unhairing, 110 ℃ of oven dry down, grind afterwards then, obtain 120 purpose Ungula Cervi.
Herba Asari is ground to 120 orders after drying.
Radix Saposhnikoviae is ground to 120 orders after drying.
Rhizoma Chuanxiong is ground to 120 orders after drying.
The Radix Angelicae Dahuricae is ground to 120 orders after drying.
With the above-mentioned material powder mix homogeneously that obtains, obtain pharmaceutical composition A 1, wherein, the content of each raw material is as shown in table 1.
Embodiment 2-5
Embodiment 2-5 is used to prepare pharmaceutical composition provided by the invention.
Method according to identical with embodiment 1 obtains pharmaceutical composition A 2-5, and wherein, the granularity and the content of each raw material are as shown in table 1.
Table 1
Embodiment 6-9
This embodiment is used to illustrate the effect of pharmaceutical composition provided by the invention.
Embodiment 1-4 is made pharmaceutical composition A 1-4 mix with 1: 100 weight ratio, obtain water slurry B1-4 with 40 ℃ water.
(1) to the therapeutic effect of foot hyperhidrosis
Select 100 foot hyperhidrosis patients (symptom: foot vesicle and erosion), be divided into 5 groups (every group of 20 patients) at random, wherein, 4 groups of patients respectively every night with water slurry B1-4 foot bath 5 minutes (treatment group), 1 group of patient every night is with 40 ℃ blister foot 5 minutes (matched group).After one month, the cure rate of observing the patient of 4 treatment groups is respectively 80%, 85%, 75% and 80%, and the patient's of matched group cure rate is 15%.Described cure rate is meant that the patient's of transference cure number accounts for the percentage ratio of test number.
(2) to the hypokinetic therapeutic effect of sweaty foot glandular secretion
Select 100 sweaty foot glandular secretion hypofunction patients (symptom: it is hemorrhage to chap), be divided into 5 groups (every group of 20 patients) at random, wherein, 4 groups of patients respectively every night with water slurry B1-4 foot bath 5 minutes (treatment group), 1 group of patient every night is with 40 ℃ blister foot 5 minutes (matched group).After one month, the cure rate of observing the patient of 4 treatment groups is respectively 70%, 75%, 80% and 80%, and the patient's of matched group cure rate is 10%.Described cure rate is meant that the patient's of transference cure number accounts for the percentage ratio of test number.
(3) to heel treatment of pain effect
Select 100 heel pain patients (symptoms: heel pain), be divided into 5 groups (every group of 20 patients) at random, wherein, 4 groups of patients respectively every night with water slurry B1-4 foot bath 5 minutes (treatment group), 1 group of patient every night is with 40 ℃ blister foot 5 minutes (matched group).After two months, the cure rate of observing the patient of 4 treatment groups is respectively 70%, 75%, 80% and 80%, and the patient's of matched group cure rate is 5%.Described cure rate is meant that the patient's of transference cure number accounts for the percentage ratio of test number.
Embodiment 10
This embodiment is used to illustrate the effect of pharmaceutical composition provided by the invention.
Embodiment 5 is made pharmaceutical composition A 5 and glutinous rice flour mixes with 1: 1: 6 weight ratio with water,, make paste 100 ℃ of heating 15 minutes down; The paste that obtains is coated on the cloth, cloth is sewn into shoe pad and natural drying, make shoe pad C1, wherein, pharmaceutical composition accounts for 5 weight % of cloth.
Cloth is sewn into shoe pad C2.
(1) to the therapeutic effect of foot hyperhidrosis
Select 40 foot hyperhidrosis patients (symptom: foot vesicle and erosion), be divided into 2 groups (every group of 20 patients) at random, wherein, 1 group of patient uses shoe pad C1 (treatment group) every day, and 1 group of patient uses shoe pad C2 (matched group) every day.After one month, the cure rate of observing the patient of treatment group is 80%, and the patient's of matched group cure rate is 0%.Described cure rate is meant that the patient's of transference cure number accounts for the percentage ratio of test number.
(2) to the hypokinetic therapeutic effect of sweaty foot glandular secretion
Select 40 sweaty foot glandular secretion hypofunction patients (symptom: it is hemorrhage to chap), be divided into 2 groups (every group of 20 patients) at random, wherein, 1 group of patient uses shoe pad C1 (treatment group) every day, and 1 group of patient uses shoe pad C2 (matched group) every day.After one month, the cure rate of observing the patient of treatment group is 75%, and the patient's of matched group cure rate is 5%.Described cure rate is meant that the patient's of transference cure number accounts for the percentage ratio of test number.
(3) to heel treatment of pain effect
(symptom: heel pain), be divided into 2 groups (every group of 20 patients) at random, wherein, 1 group of patient uses shoe pad C1 (treatment group) every day, and 1 group of patient uses shoe pad C2 (matched group) every day to select 40 heel pain patients.After two months, the cure rate of observing the patient of treatment group is 70%, and the patient's of matched group cure rate is 5%.Described cure rate is meant that the patient's of transference cure number accounts for the percentage ratio of test number.
From the measurement result of above embodiment as can be seen, pharmaceutical composition provided by the invention can effectively prevent and/or treat foot affliction.
Claims (7)
1, a kind of pharmaceutical composition, it is characterized in that, this pharmaceutical composition contains following raw material: Ungula Cervi, Herba Asari, Radix Saposhnikoviae, Rhizoma Chuanxiong and the Radix Angelicae Dahuricae, wherein, with respect to the Ungula Cervi of 100 weight portions, the content of Herba Asari is the 20-500 weight portion, and the content of Radix Saposhnikoviae is the 20-500 weight portion, the content of Rhizoma Chuanxiong is the 20-500 weight portion, and the content of the Radix Angelicae Dahuricae is the 20-500 weight portion.
2, pharmaceutical composition according to claim 1, wherein, with respect to the Ungula Cervi of 100 weight portions, the content of Herba Asari is the 50-200 weight portion, the content of Radix Saposhnikoviae is the 50-200 weight portion, and the content of Rhizoma Chuanxiong is the 50-200 weight portion, and the content of the Radix Angelicae Dahuricae is the 50-200 weight portion.
3, pharmaceutical composition according to claim 1 and 2, wherein, this pharmaceutical composition also contains Alumen, and with respect to the Ungula Cervi of 100 weight portions, the content of Alumen is the 10-500 weight portion.
4, pharmaceutical composition according to claim 1, wherein, described raw material is a powder, particle mean size is the 80-150 order.
5, any described pharmaceutical composition among the claim 1-4 is used for preventing or treating the application of the medicine of foot affliction in preparation.
6, application according to claim 5, wherein, described foot affliction is selected from one or more in foot hyperhidrosis, the hypofunction of sweaty foot glandular secretion and the heel pain.
7, a kind of shoe pad product, it is characterized in that, this shoe pad product comprise the shoe pad main body and the treatment effective dose claim 1-4 in any described pharmaceutical composition, described pharmaceutical composition is filled in the described shoe pad main body and/or loads on the described shoe pad main body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101332920A CN101632697B (en) | 2008-07-25 | 2008-07-25 | Medicinal composition, application thereof and shoe pad product thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101332920A CN101632697B (en) | 2008-07-25 | 2008-07-25 | Medicinal composition, application thereof and shoe pad product thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101632697A true CN101632697A (en) | 2010-01-27 |
| CN101632697B CN101632697B (en) | 2012-03-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008101332920A Expired - Fee Related CN101632697B (en) | 2008-07-25 | 2008-07-25 | Medicinal composition, application thereof and shoe pad product thereof |
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| CN101991239A (en) * | 2010-04-05 | 2011-03-30 | 赖长卿 | Health care insoles of traditional Chinese medicine |
| CN105169320A (en) * | 2015-09-16 | 2015-12-23 | 杰恩斯·沙比提 | Traditional Chinese medicine composition for removing foot sweat |
| CN107938330A (en) * | 2017-11-18 | 2018-04-20 | 肖本燕 | Dandelion pieces of old cloth or rags production method |
| CN107927996A (en) * | 2017-11-18 | 2018-04-20 | 肖本燕 | Pine needle pieces of old cloth or rags production method |
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| CN101991239A (en) * | 2010-04-05 | 2011-03-30 | 赖长卿 | Health care insoles of traditional Chinese medicine |
| CN101991239B (en) * | 2010-04-05 | 2015-01-21 | 赖长禧 | Health-care shoe-pad with traditional Chinese medicine |
| CN105169320A (en) * | 2015-09-16 | 2015-12-23 | 杰恩斯·沙比提 | Traditional Chinese medicine composition for removing foot sweat |
| CN107938330A (en) * | 2017-11-18 | 2018-04-20 | 肖本燕 | Dandelion pieces of old cloth or rags production method |
| CN107927996A (en) * | 2017-11-18 | 2018-04-20 | 肖本燕 | Pine needle pieces of old cloth or rags production method |
| CN108049190A (en) * | 2017-11-18 | 2018-05-18 | 肖本燕 | Thyme pieces of old cloth or rags production method |
| CN108041756A (en) * | 2017-11-18 | 2018-05-18 | 肖本燕 | Pomegranate seed pieces of old cloth or rags production method |
| CN108049189A (en) * | 2017-11-18 | 2018-05-18 | 肖本燕 | Folium artemisiae argyi pieces of old cloth or rags production method |
| CN108060578A (en) * | 2017-11-18 | 2018-05-22 | 肖本燕 | Pueraria lobata pieces of old cloth or rags production method |
| CN108085990A (en) * | 2017-11-18 | 2018-05-29 | 肖本燕 | A kind of pieces of old cloth or rags production method for going to eliminate the unusual smell |
| CN108078067A (en) * | 2017-11-18 | 2018-05-29 | 肖本燕 | Radix Folium Allii tuberosi pieces of old cloth or rags production method |
| CN108078063A (en) * | 2017-11-18 | 2018-05-29 | 肖本燕 | Okra pieces of old cloth or rags production method |
| CN108085991A (en) * | 2017-11-18 | 2018-05-29 | 肖本燕 | Aloe pieces of old cloth or rags production method |
| CN108085992A (en) * | 2017-11-18 | 2018-05-29 | 肖本燕 | Ramulus mori pieces of old cloth or rags production method |
| CN108078064A (en) * | 2017-11-18 | 2018-05-29 | 肖本燕 | Chinese prickly ash pieces of old cloth or rags production method |
| CN108095243A (en) * | 2017-11-18 | 2018-06-01 | 肖本燕 | Tung oil tree pieces of old cloth or rags production method |
| CN108103793A (en) * | 2017-11-18 | 2018-06-01 | 肖本燕 | Cimicifugae foetidae pieces of old cloth or rags production method |
| CN108095244A (en) * | 2017-11-18 | 2018-06-01 | 肖本燕 | Sponge gourd pieces of old cloth or rags production method |
| CN108095242A (en) * | 2017-11-18 | 2018-06-01 | 肖本燕 | Green tea powder pieces of old cloth or rags production method |
| CN108095241A (en) * | 2017-11-18 | 2018-06-01 | 肖本燕 | Cattail pollen pieces of old cloth or rags production method |
| CN108158128A (en) * | 2017-12-28 | 2018-06-15 | 肖本燕 | A kind of pieces of old cloth or rags production method of antibacterial insect prevention |
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| CN101632697B (en) | 2012-03-14 |
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Inventor after: Sun Lihui Inventor after: Qi Donghua Inventor after: Nie Guohuai Inventor after: Li Yuewen Inventor after: Chen Fengyou Inventor after: Zhang Yun Inventor before: Sun Lihui Inventor before: Qi Donghua Inventor before: Nie Guohuai Inventor before: Li Yuewen Inventor before: Chen Fengyou Inventor before: Zhang Yunshuang |
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Free format text: CORRECT: INVENTOR; FROM: SUN LIHUI QI DONGHUA NIE GUOHUAI LI YUEWEN CHEN FENGYOU ZHANG YUNSHUANG TO: SUN LIHUI QI DONGHUA NIE GUOHUAI LI YUEWEN CHEN FENGYOU ZHANG YUN |
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