CN101610672A - Pesticide combination - Google Patents

Abstract

The method of control growing and/or control or prevention pathogenicity and/or damage by disease and insect infringement in plant propagation material, plant, plant part and/or late period growing plants organ, it comprises pesticide combination is applied to plant, plant part or its environment, described pesticide combination is with random order or comprise simultaneously, for example at least two kinds of active ingredient components and one or more optional conventional formulation assistant agents, wherein component (I) is that one or more agricultural chemicals and component (II) are isoflavones (formononetin, genistein or its mixing).

Description

Pesticide combination

The present invention relates to definite combination of pesticide activity component and composition thereof purposes and by with compound administration to the plant propagation material with this combination method that particularly controlling plant growth and/or control or prevention pathogenicity and/or damage by disease and insect damage in described plant propagation material and late period growing plants organ.

Some combination of the active component that is used for preventing and treating pathogen and damage by disease and insect has been described in the document.The biological property of these known combination is not entirely satisfactory in the field of for example cause of disease control, phytotoxicity and environment and operating personnel's exposure.Particularly pathogen or risky becoming aforementioned known combination is had under the situation of resistance, then to seek improved control or prevention method.

When independent use or with blade face or ditch in the using when using in combination of active component, be that target is used with active component protective plant propagating materials (particularly seed), its part solves reducing the needs that environment and operating personnel expose.

Existence is to providing the lasting needs of pesticide combination, and it improves improved characteristic, and for example, biological property and/or synergism characteristic are used for controlling plant growth and control pathogen and damage by disease and insect especially.

According to the present invention,, pesticide combination of the present invention solved above-mentioned needs by being provided.Therefore, in first kind of embodiment, the invention provides the pesticide combination that seed is used, it comprises at least two kinds of active ingredient components, randomly with one or more conventional formulation assistant agents, wherein component (I) is that one or more agricultural chemicals and component (II) are one or more isoflavones.

The agricultural chemicals example that can be used in the component of the present invention (I) comprises fungicide, insecticide, nematocide, miticide and invertebrate poison.Also comprise plant growth regulator and plant activator.

The example of fungicide comprises azole fungicide, and it comprises benzimidazole fungicide, methoxy acrylate class, adjacent cyclopropyl-carbanilide derivative, phenylpyrrole class and other fungicide.The example of Fungicidally active component includes, but not limited to following compound, their salt and ester: Fluoxastrobin; M 9834; Smart M 9834; Benomyl; Benthiozole; Bitertanol; Boscalid; Bluopyram; Than husky fragrant (bixafen); Captan; Carbendazim; Carboxin; Ring propionyl bacterium amine; Chloroanisole; Cu ₂O; Frost urea cyanogen; Cyproconazole; Cyprodinil; Dichlofluanid; Difenoconazole; Alkene azoles alcohol; Enestroburin (enestrobin); Fluorine ring azoles; Oxazole bacterium ketone; Fenamidone; Fenpiclonil; Fludioxonil; Fluoxastrobin, Fluquinconazole; Flusilazole; Flutolanil; Flutriafol; Phosethyl-Al; Furidazol; Furalaxyl; Guazatine acetate; Own azoles alcohol; Hymexazo; Press down mould azoles; Glyoxalin; Iminoctadine triacetate; Plant the bacterium azoles; Iprodione; Kresoxim-methyl; Mancozeb; Maneb; Metalaxyl; Metalaxyl-M; Metconazole; SSF 126; Nitrile bacterium azoles; Ether bacterium amine (orysastrobin); The spirit of Evil frost; The Evil imidazoles; The spirit of Evil frost; Pcnb; Pefurazoate; Penconazole; Pencycuron; ZEN 90160; Prochloraz; Propiconazole; Prothioconazoles; Pyroquilon; Phonetic mould amine; Pyraclostrobin; (±)-cis-1-(4-chlorphenyl)-2-(1H-1,2,4-triazol-1-yl) suberol; 5-chloro-7-(4-methyl piperidine-1-yl)-6-(2,4, the 6-trifluorophenyl)-[1,2,4] triazols [1,5-a] pyrimidine; The silicon metsulfovax; Simeconazoles; Volution bacterium amine; Tebuconazole; Probenazole; Thiophanate-methyl; Tmtd; Tolelofos-methyl; Tolylfluanid; Triazoxide; Triazolone; Triadimenol; Oxime bacterium ester; Fluorine bacterium azoles; Triticonazole; Uniconazole P; Formula (AA) compound comprises its salt and ester

Formula (BB) compound comprises its salt and ester

Neighbour-cyclopropyl-carbanilide derivative includes, but not limited to compound, salt, ester, stereoisomer and the stereoisomer mixture of formula I, is represented by following formula:

Wherein

R _xBe trifluoromethyl or difluoromethyl and

R _yBe hydrogen or methyl; Or the dynamic isomer of this compound, in neighbour-cyclopropyl-carbanilide derivative, compound is wherein represented wherein R especially _xBe difluoromethyl and R _yBe the formula I of hydrogen _ICompound and R wherein _xBe difluoromethyl and R _yBe the formula I of hydrogen _IIThe content of the racemic compound of the racemic mixture of compound is 65-99% weight; With formula CC compound

The example of preferred fungicide comprises following compound and their salt and ester: Fluoxastrobin, Enestroburin, oxime bacterium ester, Difenoconazole, fludioxonil, probenazole, Tebuconazole, metalaxyl, Metalaxyl-M, nitrile bacterium azoles, fluoxastrobin, pyraclostrobin, triticonazole, prothioconazoles, formula I _I-I _IVNeighbour-cyclopropyl-carboxamide derivatives, formula (AA) compound, formula (BB) compound, formula (CC) compound, 5-chloro-7-(4-methyl piperidine-1-yl)-6-(2,4, the 6-trifluorophenyl)-[1,2,4] triazols [1,5-a] pyrimidine and ZEN 90160.

The example of insecticide, miticide, nematocide and invertebrate poison is, for example but be not to limit, the representative of following active component classification: organic phosphorus compound, nitrophenol and derivative, formamidine, pyrrolotriazine derivatives, macrolides, Nitroenamine derivatives, nitro-and cyanoguanidine, ureas, benzoyl area kind, carbamates, pyrethroid, chlorinated hydrocarbons and bacillus thuringiensis,Bt (Bacillus thuringiensis) product.

The example of special insecticide, miticide, nematocide and invertebrate poison comprises Avermectin; Orthene; Acetamiprid; Acrinathrin; Alanycarb; Aldicarb; α-cypermethrin; Alpha-cypermethrin; Amitraz; Azinphos ethyl; Azinphos-methyl; Azacyclotin; Evil worm prestige; Benfuracard micro; Bensultap; β-cyfloxylate; Biphenthrin; Halfenprox (brofenprox); Bromophos A; Metalkamate; Buprofezin; Butocarboxim (butocarboxin); The butyl pyridaben; Cadusafos; Carbaryl; Carbofuran; Trithion; Carbosulfan; Cartap; Cloethocarb; The chlorine insect amide; Chlorethoxyfos; Chlorfenviphos (chlorfenvenphos); Fluorine pyridine urea; Chlormephos (chloromephos); Chlopyrifos (chloropyrifos); Cis-resmethrin; Cyhalothrin; Four mite piperazines; Thiophene worm amine; The cyano group imines; Cynock; Cycloprothrin; Cyfloxylate; Plictran; Decis; Demeton M; Demeton S; Demeton-methyl; The butyl ether urea; Dibutylaminothio; Dichlofenthion; Dicliphos; Ethion; Diflubenzuron; Rogor; Dimethylvinphos; MTI-446; Dioxation; Doractin; Edifenphos; According to the horse mycin; 5a,6,9,9a-hexahydro-6,9-methano-2,4; The S-sumicidin; Ethiofencarb; Ethion; Ethiprole; Ether chrysanthemum ester; Phonamiphos; Etrimfos; Fenamiphos; Fenazaquin; Fenbutatin oxide; Sumithion; Bassa; Fenothiocarb; Fenoxycarb; Fenpropathrin; Tebufenpyrad; Azoles mite ester; Fenthion; Sumicidin; Fluorine worm nitrile; Fluazinam; Flubendiamide (flubendiamide); Flucycloxuron; Flucythrinate; Flufenoxuron; Trifluoro chrysanthemum ester; Fluxofenim; Fonofos; Formothion; Lythidathion; Trifluoro chrysanthemum ester; Gamma-cyhalothrin; Hexachlorcyclohexane; Heptenophos; Fluorine bell urea; Hexythiazox; Imidacloprid; Iprobenfos; Mobucin; Oxazole phosphorus; Olivomitecidin; λ-cyhalothrin; Lindane; The Acarus tritici urea; The malathion; Afos; The first oxydemeton_methyl; The methaldehyde; Acephatemet; Methiocarb; Methomyl; Meta-tolyl-N-methylcarbamate (MTMC); Menite; More visit rhzomorph; More visit the rhzomorph oxime; Moxidectin; 2-dichloroethylk dimethyl phosphate; NC 184; Nitenpyram; Nitromethylene; Omethoate; Oxamyl; Oxydemeton_methyl; Oxydeprofos; Parathion; Parathion-methyl; Permethrin; Phenthoate dimephenthoate cidial; Thimet; Phosalone; Phosmet; Phoxim; Aphox; Diothyl A; Diothyl M; Carbamult; Kayaphos; Unden; Toyodan; Prothoate; Pyrrole aphid ketone; Pyraclofos; Pyridaphethione; Anti-Chryson; Pyrethrin; Pyridaben; Pyrimidifen; The pyrrole propyl ether; The pyrrole propyl ether; Chlorine insect amide (rynaxypyr); Salithion; Cadusafos; Silafluofene; Sulfotep; Sulprofos; The worm hydrazides; Tebufenpyrad; Butyl pyrimidine phosphorus; The fluorobenzene urea; Tefluthrin; Swebate; Terbam; Terbufos; Ravap; Thiophene worm quinoline; Thiafenox; Thiophene worm piperazine; The two prestige of sulphur; Thiofanox; Thionazin; The Su Li rhzomorph; Tralomethrin; Triarathene; Triaguron; Hostathion; Triazuron; Chlorophos (trichlorofon); Kill the bell urea; Landrin; Vamidothion; Meobal; ξ-cypermethrin; Zetamethrin; And (Bt) product of bacillus thuringiensis,Bt (Bacillus thuringiensis), comprise its salt and ester.

The example of preferred insecticide, miticide, nematocide and invertebrate poison comprises the two prestige of Avermectin, Acetamiprid, Aldicarb, β-cyfloxylate, carboxin, chlorine insect amide, thiophene worm amine, Bt product, MTI-446, fluorine worm nitrile, Imidacloprid, λ-cyhalothrin, Nitenpyram, pleocidin, tefluthrin, thiophene worm quinoline, thiophene worm piperazine and sulphur.

The example of plant growth regulator comprises, but be not limited to, anti-auxin (chlorine shellfish acid, 2,3,5-three-iodo-benzoic acid), auximone (chlorophenoxyacetic acid, 2,4-drips, 2, the 4-Embutox, 2,4-drips phosphorus (2,4-DEP), 2,4-drips propionic acid, 2,4,5-tears propionic acid, heteroauxin, IBA, naphthalene acetamide, α-Nai Yisuan, the 1-naphthol, naphthoxyacetic acid, cyclic potassium naphthenate, sodium naphthenate, 2,4, the 5-tears), activin (2iP, benayl aminopurine, kinetin, zeatin), defoliant (nitrolim, dimethipin, the bacterium polyacid, ethrel, merphos, metoxuron, pentachlorophenol, Thidiazuron, De-Green), ethylene inhibitor (Ai Wei hormone (aviglycine), the 1-methyl cyclopropene), ethene releasing agent (ACC, ethene silicon, ethrel, glyoxime), gibberellin (gibberellic acid, gibberellin, comprise the non-compound cyclopropene that shows similar gibberellin activity, such as, helminthosporic acid for example, phaseolic acid, kaurenoic acid and stevia rebaudianum alcohol), growth inhibitor (abscisic acid, ancymidol, butralin, carbaryl, three fourth benzyl chloride phosphorus, chlorpropham, dikegulac, flumetralim, fluoridamid, ioxynil, increase sweet phosphine, different phonetic alcohol, jasmonic, maleic hydrazide, the first piperazine, piperazine is strong plain, the jasmonic inductor, propham, 2,3,5-three-iodo-benzoic acid), morphactin (chlorflurenol, chloroflurenol, the dichloro flurenol, flurenol), growth retardant/modifying agent (chlormequat, daminozide, the phonetic alcohol of fluorine, mefluidide, paclobutrazol, Cyproconazole, tetcyclacis, uniconazole P, ancymidol, anti-ester and accent naphthenic acid-CA), growth promoter (brassinosteroid, forchlorfenuron hymexazo, 2-amino-6-oxygen base purine derivative is described below indolinone derivative, be described below, 3, the dibasic maleimide derivatives of 4-is described below, azatropylidene ketone derivatives with condensing is described below).This term also comprises active component, presses down androsin (fenridazon), heptopargil, holosulf, inabenfide, karetazan, lead arsenate, methasulfocarb, accent naphthenic acid, pyrrole such as fluorine straw colour, fourth ring grass phosphorus, carvol, ciobutide, clofencet, cloxyfonac, cyclanilide, cycloheximide, epocholeone, 'Inshuzhi ', ethene, pyridazine and reaches farming (pydanon), sintofen, triapenthenol and the anti-ester that falls.Other plant growth regulator comprises indolinone derivative plant stimulant, is described in WO 2005/107466; 3, the dibasic maleimide derivatives of 4-is described in WO 2005/107465; The azatropylidene ketone derivatives that condenses is described in WO 2005/107471; With 2-amino-6-oxygen base purine derivative, be described in WO2005/107472.

The example of preferred plant growth regulator comprises growth retardant, and the gibberellin class comprises gibberellic acid, growth inhibitor and growth promoter.Particularly preferred plant growth regulator comprises growth retardant, paclobutrazol particularly, and Cyproconazole, the phonetic alcohol of fluorine, anti-ester and uniconazole P and the gibberellin class of falling comprises gibberellic acid, particularly GA ₃, GA ₄+ GA ₇, and salt and ester-formin.

The example of plant activator includes, but not limited to Acibenzolar, irritated pathogenicity proteins, probenazole and big Gentrin Knotweed P.E (reynoutria sachalinensis) (reysa).Preferred plant activator is Acibenzolar and irritated pathogenicity proteins.

Isoflavones is the phytochemicals that extensively exists in the leguminous plant member.They are based on simple phenol ring structure, for example by people such as Carlson (1980) Journal ofChromotography, and 198,193-197 and US Patent No.7033621 describe, and incorporate its content into this paper by reference.The example that can be used for the isoflavones in the component of the present invention (II) comprises, but be not limited to genistein (genistein), biochanin A, formononetin (formononetin), Daidezin, Glycitein, hesperetin, naringenin, chalcone, coumarin, Ambiol (2-methyl-4-[dimethylaminomethyl]-5-hydroxy benzo imidazoles), ascorbate and pratensein and salt and ester.Formononetin, hesperetin, naringenin and salt thereof, ester and mixture are preferred isoflavones.The present invention considers to use natural generation and synthetic isoflavone compounds.

In second kind of embodiment, the invention provides the method for in plant propagation material, plant, plant part and/or late period growing plants organ controlling plant growth or control or infringement of prevention pathogen or damage by disease and insect infringement, it comprises to described plant, plant part or its environment with any desired sequence or defined combination in using as first kind of embodiment simultaneously.

In the third embodiment; the invention provides the method for protective plant propagating materials, plant, plant part and/or growing plants organ antagonism pathogen infringement in late period or damage by disease and insect infringement, its by to described plant, plant part or its environment with any desired sequence or defined combination in using as first kind of embodiment simultaneously.

The invention still further relates to the plant propagation material of handling with defined combination in first kind of embodiment.

In other embodiment, the present invention relates to this method; it comprises (i) and comes treatment of plant propagation material such as seed with defined pesticide combination in first kind of embodiment; (ii) plant or sow treated plant propagation material, thereby described treated plant propagation material, plant part and/or the growth of wherein said combined protection is from the plant antagonism pathogen infringement or the damage by disease and insect infringement of described treated plant propagation material.

In addition; the present invention relates to this method in another embodiment; it comprises (i) and comes treatment of plant propagation material such as seed with defined pesticide combination in first kind of embodiment; (ii) plant or sow treated plant propagation material and (iii) realize plant antagonism pathogen infringement or the damage by disease and insect infringement of described treated plant propagation material, plant part and/or the growth of protection from described treated plant propagation material.

In the preferred implementation aspect the present invention is any, each combination is a composition, and it preferably comprises each one or more (I), (II) and one or more optional conventional formulation auxiliary agents.

Defined component (I), (II) are the active components (being also referred to as agricultural chemicals) that is used for agrochemical field in first kind of embodiment.The structure and the description of other agricultural chemicals (fungicide, insecticide, nematocide) to them can be referring to the e-Pesticide Manual, version 3 .1, and the 13rd edition, CDC Tomlin writes, British Crop Protection Council, 2004-05.

Control in the context of the invention, prevention or protection and variation thereof be meant any undesired effect, such as

-pathogen property, such as phytopathogen, particularly fungoid infect or attack and

Infringement of-pathogen or damage by disease and insect infringement

On plant, plant part or plant propagation material, be reduced to and show improved level.

In the context of the invention, the controlling plant growth means quickening or delays seed sprouting, comprises the method that makes plant emerge synchronously and/or bloom; Obtain having the plant of thicker stem and/or littler canopy; Obtain needing less input such as water, fertilizer, illumination etc. plant.

Pesticide combination of the present invention has very favorable plant protection characteristic, and its antagonism (i) pathogenicity is such as causing the particularly fungoid invasion and attack or infect of plant characteristic of disease, and it causes the disease of plant and infringement and/or (ii) damage by disease and insect invasion and attack or infringement; Particularly under the situation of plant, the present invention can prevent and treat or prevent seed, plant part and/or growth pathogen infringement and/or the damage by disease and insect infringement on the plant of treated seed.In addition, pesticide combination according to the present invention has emerging of very favorable controlling plant and/or seed and growth characteristics.

These characteristics are for example effects of the enhancing of the combination of one or more compound (I), (II), thereby cause lower pathogen infringement and/or damage by disease and insect infringement, lower rate of application and/or long acting duration.Under agriculture situation, the effect of finding described enhancing shows the improvement of plant growing feature, for example, delay emerge and/or pathogenicity is infected and/or the expection control of damage by disease and insect infringement higher.

The improvement of described plant growing feature can show as different ways, but it finally causes better plant production.It can show as, and for example improves plant products and/or vigor or the results quality from the product of plant, and this improves may or can not be relevant with the control of disease and/or damage by disease and insect.

As used herein, wording " improvement plant products " but relate to the increase of plant product output measuring amount, contrast similarity condition output of identical plant product down but when not using subject methods.Preferred output increases at least about 0.5%, more preferably increases, even more preferably from about 2% at least about 1%, and also more preferably from about 4%, or more than.Output can be expressed as the amount of the weight and volume of the plant product on certain benchmark, the amount of product of perhaps can going on the market and the quality of this product.Described benchmark can be expressed as time, growth area, the plant weight of being produced, raw materials used amount etc.

As used herein, wording " improvement plant vigor " relates to the increase or the improvement of measuring of following factor or observable amount: motility grade, or plant spacing (the plant number of unit are), or plant height, or the plant canopy, or visual appearance (such as greener leaf look), or the root system evaluation, or emerge, or protein content, or tillering of increasing, or bigger blade, or withered basic leaf still less, or stronger tillering, or fertilizer demand still less, or seed demand still less, or more voluminous tillering, or prematurity more, or cereal precocity, or plant still less topples over (lodging), or stem branch growth that increases or rudiment more early, or any combination of these factors, perhaps any other advantage of being familiar with of those skilled in the art, contrast similarity condition are down but the same factor of the plant that is produced when not using subject methods.

When explanation the inventive method can " be improved plant products and/or vigor ", the inventive method caused aforesaid output to increase, and perhaps aforesaid plant vigor increases, and perhaps output and vegetable active all increase.

Therefore, the present invention also provides the method for the growth characteristics that improves plant, its to described plant and/or plant part with any desired sequence or use simultaneously as the defined combination of first aspect.

Component (I) is described below with the appointment that is provided in the table 1 with the concrete preferred compositions of component (II), and wherein, for example, Fluoxastrobin is that compd A 1, gibberellic acid are that Compound C 6, formononetin are compd E 3, and is like that.Those of ordinary skills should understand each and all combination that the present invention includes from the active component of one or more hurdles A, B, C, D or E compound, and condition is to have at least a hurdle E compound.It is as follows that preferred embodiment provides:

Table 1

	Fungicide (A)	Nematocide or insecticide (B)	??PGR(C)	Activator (D)	Isoflavones (E)
						??1	Fluoxastrobin	Avermectin	Paclobutrazol	Acibenzolar	Formononetin
??2	Difenoconazole	Thiophene worm quinoline	Cyproconazole	Irritated pathogenicity proteins	Genistein
						??3	Fludioxonil	Thiophene worm piperazine	Anti-ester
??4	Fluoxastrobin	The two prestige of sulphur	Uniconazole P
						??5	Metalaxyl-M	Tefluthrin	Gibberellic acid
??6	Metalaxyl	Thiophene worm amine	??GA 3
						??7	Tmtd	The Bt product	??GA 4+GA 7
??8	Triticonazole	Pleocidin
						??9	Tebuconazole	Fluorine worm nitrile
??10	Probenazole	Imidacloprid
						??11	Oxime bacterium ester	λ-cyhalothrin
??12	Formula I neighbour-cyclopropyl-carbanilide
						??13	Pyraclostrobin
??14	Formula (CC) compound
						??15	Prothioconazoles

A1+E1；A1+E2；A2+E1；A2+E2；A3+E1；A3+E2；A4+E1；A4+E2；A5+E1；A5+E2；A6+E1；A6+E2；A7+E1；A7+E2；A8+E1；A8+E2；A9+E1；A9+E2；A10+E1；A10+E2；A11+E1；A11+E2；A12+E1；A12+E2；A13+E1；A13+E2；A14+E1；A14+E2；A15+E1；A15+E2；

B1+E1；B1+E2；B2+E1；B2+E2；B3+E1；B3+E2；B4+E1；B4+E2；B5+E1；B5+E2；B6+E1；B6+E2；B7+E1；B7+E2；B8+E1；B8+E2；B9+E1；B9+E2；B10+E1；B10+E2；B11+E1；B11+E2；

C1+E1；C1+E2；C2+E1；C2+E2；C3+E1；C3+E2；C4+E1；C4+E2；C5+E1；C5+E2；C6+E1；C6+E2；C7+E1；C7+E2；

D1+E1；D1+E2；D2+E1；D2+E2。

The present invention also provides the combination of one or more described agricultural chemicals and isoflavones combination.Therefore, provide hereinafter preferred concrete 3-, 4-and the combination of 5-unit, those appointments that provided in appointment of using in the table 1 to be provided and the table 2.

Table 2

??Z1	(A5+A6)+(A3 or A7)	??Z12	(A3 or A7)+(A8, A9 or A15)
				??Z2	Z1+ (A1, A4, A11 or A13)	??Z13	Z1+ (A8, A9 or A15)
??Z3	??Z2+A10	??Z14	Z1+ (A12 or A14)
				??Z4	??Z1+A2	??Z15	Z2+ (A12 or A14)
??Z5	??Z2+A2	??Z16	(A1, A4, A11 or A13)+(A12 or A14)
				??Z6	A2+ (A3 or A7)	??Z17	(A1, A4, A11 or A13)+(A8, A9 or A15)
??Z7	(A1, A4, A11 or A13)+A2	??Z18	Z1+ (A8, A9 or A15)
				??Z8	A2+ (A5 or A6)	??Z19	Z2+ (A8, A9 or A15)
??Z9	(A1, A4, A11 or A13)+(A5 or A6)	??Z20	??Z1+A10
				??Z10	Z2+ (A12 or A14)	??Z21	(A1, A4, A11 or A13)+A10
??Z11	Z1+ (A12 or A14)

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Each combination of the present invention can be used in the disease of coming in agriculture field and the related application field on controlling plant growth and/or control or the prevention plant and infect and/or the damage by disease and insect infringement.

Each combination of the present invention that comprises fungicide effectively resists the phytopathogenic fungi that belongs to following classification, particularly occur in the plant those, comprise the fungi of kind of biography: Ascomycetes (Ascomycetes) (for example Penicillium (Penicillium), gaeumannomyce bacterium (Gaeumannomyces graminis)); Basidiomycetes (Basidiomycetes) (for example hunchbacked spore Rust (Hemileia), Rhizoctonia (Rhizoctonia), Puccinia (Puccinia)); Fungi Imperfecti (Fungi imperfecti) (Botrytis (Botrytis) for example, Helminthosporium (Helminthosporium), Rhynchosporium spp (Rhynchosporium), Fusarium (Fusarium), Septoria (Septoria), Cercospora (Cercospora), prop up spore and belong to (Cladosporium), Colletotrichum (Colletotrichum), Alternaria (Alternaria), the rotten germ (Pseudocercosporella herpotrichoides) of Pyricularia Sacc. (Pyricularia) and wheat-based); Oomycete (Oomycetes) (for example Phytophthora (Phytophthora), Peronospora (Peronospora), Bremia (Bremia), pythium (Pythium), Plasmopara (Plasmopara), false Peronospora (Pseudoperonospora)); Zygomycetes (Zygomycetes) (for example Rhizopus (Rhizopus spp.)).Combination resists Alternaria (Alternariaspp.) especially effectively, aspergillus (Aspergillus spp.), ergot (Claviceps purpurea), Curvularia (Cochliobolus spp.), Colletotrichum (Colletotrichum spp.), maize two spores (Diplodia maydis), standing grain powdery mildew (Erysiphe graminis), Fusarium (Fusarium spp.) is (such as yellow sickle spore bacterium (Fusarium culmorum), fusarium oxysporum bacterium (Fusarium oxysporium), fusariun solani (Fusarium solani), F.graminearum schw (Fusarium graminearum) and rice are disliked seedling sickle spore (Fusariummoniliforme)), gaeumannomyce bacterium (Gaeumannomyces graminis), Chinese sorghum stem rot germ (Giberella fujikuroi), Gibberella zeae (Giberella zeae), the standing grain length spore (Helminthosporium graminearum) of wriggling, avenge rotten bright shuttle spore and belong to (Monographella nivalis), Puccinia (Puccinia spp.), nuclear cavity Pseudomonas (Pyrenophora spp.) (such as wheat class nuclear cavity bacteria (Pyrenophora graminea)), corn downy mildew Pseudomonas (Peronosclerospora spp.), Peronospora (Peronsporaspp.), yam bean layer rust (Phakopsora pachyrhizi), rotten mold genus (Phythiumspp.), Phoma (Phoma spp.), Phomopsis (Phomopsis spp.), Rhizoctonia solani Kuhn (Rhizoctonia solani), Septoria (Septoria spp.), false Cercosporalla (Pseudocercosporella spp.), Tilletia (Tilletia spp.), Rhizopus (Rhizopus spp.), nuclear coral Pseudomonas (Typhula spp.), Ustilago (Ustilago spp.), axle Ustilago (Sphacelotheca spp.) (for example silk axle smut (Spacelotheca reilliani)), thanatephorus cucumeris(frank) donk (Thanatephoruscucumeris) and Verticillium (Verticillium spp.).

The present invention who comprises at least a fungicide makes up the fungal pathogens that resists Fusarium (Fusarium), pythium (Pythium) and/or Rhizoctonia (Rhizoctonia) especially effectively.

The present invention who comprises at least a insecticide, nematocide, miticide or microbicidel immunomodulator compounds (I) (such as Avermectin, thiophene worm amine, Imidacloprid, thiophene worm piperazine, tefluthrin, λ-cyhalothrin) makes up effective prevention and elimination of disease and pests.In these cases, thus described combination also can be applied on the described damage by disease and insect material (for example plant and plant part) that control or pre-preventing disease and pest infringement and protection wish avoids the damage by disease and insect infringement.The example of damage by disease and insect comprises:

Lepidoptera (Lepidoptera), for example, Acleris spp belongs to (Acleris spp.), Adoxophyes spp belongs to (Adoxophyes spp.), clearwing moth belongs to (Aegeria spp.), ground Noctua (Agrotis spp.), cotton leaf ripple leaf moth (Alabama argillaceae), Amyloisspp., soybean noctuid (Anticarsia gemmatalis), Archips spp (Archips spp.), Argyrotaenia spp belongs to (Argyrotaenia spp.), bifurcation mosquito Noctua (Autographa spp.), the dried noctuid of corn (Busseola fusca), Cadra cautella (Cadra cautella), peach fruit borer (Carposina nipponensis), straw borer spp (Chilo spp.), Choristoneura spp belongs to (Choristoneura spp.), grape codling moth (Clysia ambiguella) (Clysia ambiguella), Cnaphalocrocis spp belongs to (Cnaphalocrocis spp.), cloud volume moth belongs to (Cnephasia spp.), Cochylisspp belongs to (Cochylis spp.), casebearer moth (Coleophora spp.), the fine hair snout moth's larva belongs to (Crocidolomia spp.), peach abnormity steinernema (Cryptophlebia leucotreta), Crysodeixis includens, steinernema belongs to (Cydia spp.), the bar crambid belongs to (Diatraeaspp.), the Sudan cotton bollworm (Diparopsis castanea), Jin Gang bores and belongs to (Earias spp.), phycitid belongs to (Elasmopalpus spp.), meal moth belongs to (Ephestia spp.), the flower steinernema belongs to (Eucosma spp.), ligustrum fine tortricidae (Eupoecilia ambiguella), Euproctis (Euproctis spp.), cut Noctua (Euxoa spp.), Grapholita spp belongs to (Grapholita spp.), the wide wing steinernema of cloud and mist (Hedya nubiferana), Heliothis (Heliothis spp.), Hellula undalis (Hellula undalis), fall webworm (Hyphantria cunea), tomato stem gelechiid (Keiferia lycopersicella), pear leaf blister moth (Leucoptera scitella), the thin moth of leaf mining belongs to (Lithocollethis spp.), Table Grape steinernema (Lobesia botrana), Euproctis (Lymantria spp.), lyonetid belongs to (Lyonetia spp.), Malacosoma (Malacosoma spp.), tomato moth (Mamestra brassicae), maduca sexta (Manduca sexta), autumn geometrid moth genus (Operophtera spp.), European corn borer (Ostrinia nubilalis), super steinernema belongs to (Pammene spp.), brown epiblema (Pandemis spp.), small noctuid (Panolisflammea), pink bollworm (Pectinophora gossypiella), tobacco split worm (Phthorimaea operculella), imported cabbageworm (Pieris rapae), Pier (Pierisspp.), diamond-back moth (Plutella xylostella), Xiao Bai Yponomeuta (Prays spp.), white standing grain snout moth's larva belongs to (Scirpophaga spp.), moth stem Noctua (Sesamia spp.), long palpus volume moth belongs to (Sparganothis spp.), greedy Noctua (Spodoptera spp.), clearwing moth belongs to (Synanthedon spp.), the band moth belongs to (Thaumetopoea spp.), the volume moth belongs to (Tortrixspp.), amyloid plaque noctuid (Trichoplusia ni) and Yponomeuta (Yponomeuta spp.);

Coleoptera (Coleoptera), for example, click beetle belongs to (Agriotes spp.), flower resembles genus (Anthonomus spp.), Atomaria linearis (Atomaria linearis), tortoise resembles genus (Ceutorhynchus spp.), the recessed shin flea beetle of flea (Chaetocnema tibialis), collar resembles genus (Cosmopolites spp.), Curculio (Curculio spp.), khapra beetle belongs to (Dermestes spp.), chrysomelid genus (Diabrotica spp.), epilachna genus (Epilachna spp.), Eremnus spp., soil is dived and is belonged to (Gonocephalum spp.), Europe Sarcophaga (Heteronychus spp.), colorado potato beetles (Leptinotarsadecemlineata), rice water resembles genus (Lissorhoptrus spp.), gill cockchafer belongs to (Melolontha spp.), saw-toothed grain beetle belongs to (Orycaephilus spp.), ear resembles genus (Otiorhynchus spp.), spot resembles genus (Phlyctinus spp.), dish phyllotreta (Phyllotreta spp.), cloud Pier (Popillia spp.), Protostrophusspp., flea phyllotreta (Psylliodes spp.), lesser grain borer belongs to (Rhizopertha spp.), Scarabaeidae (Scarabeidae), Sitophilus (Sitophilus spp., gelechiid belongs to (Sitotrogaspp.), powder genus (Tenebrio spp.), Tribolium (Tribolium spp.) and spot khapra beetle belong to (Trogoderma spp.);

Orthoptera (Orthoptera), for example, blattaria belongs to (Blatta spp.), Blatella (Blattella spp.), Gryllotalpa spp (Gryllotalpa spp.), leucophaea maderae (Leucophaea maderae), migratory locusts genus (Locusta spp.), Periplaneta (Periplanetaspp.) and desert locust and belongs to (Schistocerca spp.);

Isoptera (Isoptera), for example, Reticulitermes (Reticulitermes spp.);

Corrodentia (Psocoptera), for example, powder corrodent belongs to (Liposcelis spp.);

Anoplura (Anoplura), for example, Haematopinus (Haematopinus spp.), Linognathus (Linognathus spp.), Pediculus (Pediculus spp.), goitre woolly aphid belong to (Pemphigusspp.) and Japan's Aphis (Phylloxera spp.);

Mallophaga (Mallophaga), for example, Damalinia (Damalinea spp.) and Trichodectes (Trichodectes spp.);

Thrips (Thysanoptera), for example, flower thrips belongs to (Frankliniella spp.), hedge Thrips (Hercinothrips spp.), Taeniothrips (Taeniothrips spp.), palm thrips (Thrips palmi), onion thrips (Thrips tabaci) and the hard thrips of tangerine (Scirtothrips aurantii);

Heteroptera (Heteroptera), for example, Dichelops melacanthus, cocoa Di fleahopper (Distantiella theobroma), red cotton bug belongs to (Dysdercus spp.), the America stinkbug belongs to (Euchistus spp.), Eurygasterspp belongs to (Eurygaster spp.), Leptocorisa spp belongs to (Leptocorisa spp.), Bemisia spp (Nezara spp.), the skin stinkbug belongs to (Piesma spp.), Rhodnius (Rhodnius spp.), Sahlbergella singularis (Sahlbergella singularis), black stinkbug belongs to (Scotinophara spp.) and vertebra Reduvius (Triatoma spp.);

Homoptera (Homoptera), for example, fur aleyrodid (Aleurothrixusfloccosus), dish aleyrodid (Aleyrodes brassicae), the kidney Aspidiotus belongs to (Aonidiellaspp.), Aphidiadae (Aphididae), Aphis (Aphis spp.), Aspidiotus belongs to (Aspidiotusspp.), sweet potato whitefly (Bemisia tabaci), lecanium belongs to (Ceroplaster spp.), dark brown Aspidiotus (Chrysomphalus aonidium), Chrysomphalus ficus (Chrysomphalusdictyospermi), wide food Coccushesperidum (Coccus hesperidum), green jassids belongs to (Empoasca spp.), apple aphid (Eriosoma larigerum), Erythroneura spp belongs to (Erythroneura spp.), Gascardia spp., small brown rice planthopper belongs to (Laodelphaxspp.), east ball lecanium (Lecanium corni), lepidosaphes shimer (Lepidosaphesspp.), long tube Aphis (Macrosiphus spp.), tumor aphid genus (Myzus spp.), rice leafhopper belongs to (Nephotettix spp.), brown planthopper belongs to (Nilaparvata spp.), the sheet armored scale belongs to (Paratoria spp.), the goitre woolly aphid belongs to (Pemphigus spp.), stern line mealybug belongs to (Planococcus spp.), white armored scale belongs to (Pseudaulacaspis spp.), mealybug belongs to (Pseudococcus spp.), Psylla spp (Psylla spp.), cotton a red-spotted lizard (Pulvinariaaethiopica), the large bamboo hat with a conical crown and broad brim Aspidiotus belongs to (Quadraspidiotus spp.), Rhopalosiphum (Rhopalosiphum spp.), black bourch belongs to (Saissetia spp.), the band leafhopper belongs to (Scaphoideus spp.), y-bend Aphis (Schizaphis spp.), paddy net Aphis (Sitobion spp.), greenhouse whitefly (Trialeurodes vaporariorum), a mandarin orange wood louse (Triozae rytreae) and oranges and tangerines point armored scale (Unaspis citri);

Hymenoptera (Hymenoptera), for example, thorn leaf cutting ant (Acromyrmex), cabbage sawfly (Athalia rosae), leaf cutting ant belongs to (Atta spp.), the stem honeybee belongs to (Cephus spp.), pine sawfoy belongs to (Diprion spp.), diprionidae (Diprionidae), the lucky pine sawfoy (Gilpinia polytoma) of dragon spruce, real tenthredinidae (Hoplocampa spp.), the hair ant belongs to (Lasiusspp.), MonomoriumMayr (Monomorium pharaonis), new pine sawfoy belongs to (Neodiprionspp.), Solenopsis (Solenopsis spp.) and Vespa (Vespa spp.);

Diptera (Diptera), for example, Chinese sorghum awns mosquito (Antherigona soccata), garden march fly (Bibio hortulanus), little Anastrepha (Ceratitis spp.), Carysomyia (Chrysomyia spp.), Culex (Culex spp.), Cuterebra (Cuterebra spp.), few hair on the neck Anastrepha (Dacus spp.), Delia (Delia spp.), Drosophila melanogaster (Drosophila melanogaster), liriomyza bryoniae belongs to (Liriomyza spp.), black Hippelates (Melanagromyza spp.), cecidomyiia belongs to (Orseolia spp.), Oscinella frit (Oscinella frit), spinach spring fly (Pegomyia hyoscyami), grass Hylemyia (Phorbia spp.), apple is around trypetid (Rhagoletis pomonella), mushroom fly belongs to (Sciara spp.);

Acarina (Acarina), for example, Acarus siro (Acarus siro), oranges and tangerines aceria (Aceria sheldoni), steinman pin thorn goitre mite (Aculus schlechtendali), Amblyomma (Amblyomma spp.), Argas (Argas spp.), short whisker Acarapis (Brevipalpusspp.), Bryobia praetiosa (Bryobia praetiosa), Calipitrimerus spp., Psoroptes (Chorioptes spp.), Dermanyssus gallinae (Dermanyssus gallinae), carpinus turczaninowii beginning tetranychid (Eotetranychus carpini), Eriophyes (Eriophyes spp.), Hyalomma (Hyalomma spp.), meadow unguiculus mite (Olygonychus pratensis), Ornithodoros (Ornithodoros spp.), Panonychus citri belongs to (Panonychus spp.), oranges and tangerines wrinkle leaf Aculus (Phyllocoptruta oleivora), Polyphagotarsonemus latus Banks (Polyphagotarsonemus latus), the scabies mite belongs to (Psoroptes spp.), Rh (Rhipicephalus spp.), Rhizoglyphus (Rhizoglyphus spp.), itch mite belongs to (Sarcoptes spp.), tarsonemid belongs to (Tarsonemus spp.) and Tetranychus (Tetranychus spp.); With

Nematoda (Nematoda), for example, Meloidogyne (Meloidogyne spp.) (for example, watermelon root nodule nematode (Meloidogyne incoginita) and javanese root knot nematode (Meloidogyne javanica)), Heterodera (Heterodera spp.) (for example, soybean cyst nematode (Heterodera glycines), beet golden nematode (Heteroderaschachtii), oat golden nematode (Heterodora avenae) and clover golden nematode (Heterodora trifolii)), ball Heterodera (Globodera spp.) (for example, globodera rostochiensis (Globodera rostochiensis)), perforation line Eimeria (Radopholusspp.) (for example, similar similes thorne (Radopholus similes))), kidney shape Turbatrix (Rotylenchulus spp.), Pratylenchidae belongs to (Pratylenchus spp.) (for example, unelected Pratylenchidae (Pratylenchus neglectans) and Cobb root (Pratylenchus penetrans)), Aphelenchoides (Aphelenchoides spp.), helix Eimeria (Helicotylenchus spp.), tie Turbatrix (Hoplolaimusspp.), class burr Turbatrix (Paratrichodorus spp.), minute hand Turbatrix (Longidorus spp.), natural pearls Turbatrix (Nacobbus spp.), inferior serpentine Eimeria (Subanguina spp.) thorn Turbatrix (Belonlaimus spp.), little loop wire Eimeria (Criconemella spp.), wheel Turbatrix (Criconemoides spp.) Ditylenchus (Ditylenchus spp.), awl Turbatrix (Dolichodorus spp.), partly take turns Turbatrix (Hemicriconemoides spp.), sheath Turbatrix (Hemicycliophora spp.), latent root Turbatrix (Hirschmaniella spp.), Meloidogyne (Hypsoperine spp.), big nodal plate Turbatrix (Macroposthonia spp.), Melinius spp., spot rubber-insulated wire Eimeria (Punctodera spp.), five ditch Turbatrixs (Quinisulcius spp.), peltate Turbatrix (Scutellonema spp.), Xiphinema (Xiphinema spp.) and dwarfing Turbatrix (Tylenchorhynchus spp.).

Also find in another aspect of this invention, comprise (i) probenazole and (ii) Avermectin and/or class anabasine agricultural chemicals, be specially adapted to prevent and treat pathogen and damage by disease and insect damages such as the combination of thiophene worm piperazine, Imidacloprid or thiophene worm amine, particularly in soybean crops.The insect pest of the effective confrontation line parasitosis of described combination, particularly described combined administration in plant propagation material such as seed on the time.Preferred combination comprises (i) probenazole and (ii) Avermectin, and/or (iii) thiophene worm piperazine as the formononetin of component (I) and at least a natural generation or synthesized form or genistein as component (II).

Combination of the present invention can be used for special-purpose by preparation.Preferably, described combination is used for protecting cultivated plant or their propagating materials by preparation.Therefore, combination of the present invention can be applied to plant as foliar spray in a usual manner.Advantageously, described combination is used to prevent and treat by preparation or the seed treatment of pre-preventing disease and pest and/or pathogen infringement is used, and in described damage by disease and insect and/or pathogen existence and agricultural or the forestry, and can especially damage plant in early days at development of plants.

In addition, thus the present invention also comprises the soil application control soil of the present invention combination pathogen that damage by disease and insect and/or soil transmits that dwells.Method to soil application can be any suitable method, it guarantees that described combination penetrates soil, and for example the seedling case is used, use in the ditch, soil soaks medicine, soil injection, drip irrigation, to use, sneak into soil (spreading fertilizer over the fields or band application) by sprinkler or central rotating shaft all be such method.

Benefit of the present invention also can realize like this: by (a) with described combined treatment plant propagation material or (b) normally plant the site and use described combination to the place of needs controls, perhaps (a) and (b) have concurrently.

Term " plant propagation material " is interpreted as representing whole reproduction parts of plant, and such as the seed that can be used for plant propagation, and the nutrient plant material is as transplanting a cutting and stem tuber (for example potato).Therefore, as used herein, plant part comprises propagating materials.Can mention for example seed (stricti jurise), root, fruit, stem tuber, bulb, rhizome, plant part.Also can mention after germinateing or germination plant and the seedling that will transplant after from soil, emerging.Before transplanting, can protect these seedling by impregnation process in whole or in part.

Plant part and after time point growing plants organ be any plant part of growing from plant propagation material such as seed.Plant part, plant organ and plant can also be benefited from the protection to pathogen and/or damage by disease and insect infringement, and it is by realizing described combined administration to plant propagation material.In one embodiment, the certain plants organ of certain plants part and growth in late period also can be counted as plant propagation material, and himself can apply (or processing) with described combination; Therefore; growth from the plant of described treated plant part and treated plant organ, further plant part and further plant organ also can benefit from protection to pathogen and/or damage by disease and insect infringement, it is by realizing on described certain plants part of described combined administration and the certain plants organ.

With pesticide activity component and its mixture use or handle to the method for plant propagation material be known in the art, comprise seed dressing, lining, granulation and the immersion application process of plant propagation material.

Described active component can use conventional treatment technology and equipment such as fluidization, roller-crushing mill method, rotor-stator seed processing machine and drum-type lining machine to be applied to seed.Also can use other method such as spouted bed.Seed can select the footpath in advance before lining.After the lining, seed is dried usually and is transferred to machine choosing footpath, choosing footpath subsequently.Said method is as known in the art.

In a preferred embodiment, the method by not causing rudiment is with described combined administration or handle to plant propagation material; Usually the seed immersion can cause rudiment, because the water content of gained seed is too high.So the example of using the proper method of (or processing) plant propagation material such as seed is seed seed dressing, seed lining or pellet seeds etc.

Plant propagation material is seed preferably.Although this method it is believed that the seed that can be applied to any physiological status, seed preferably is in enough durable state, and it is injury-free in processing procedure.Usually, seed can be such seed, and it is gathered in the crops from the field; Remove from plant; Separation is from any cob, stem, crust and pulp on every side or other non-spermatophyte material.Seed can also preferably biologically stable, to reach the degree that processing can not cause biological damage to seed.It is believed that and any time between seed results and planting seed or during the sowing process described processing to be applied to seed (at the application of seed).Seed can also excite (primed) before or after handling.

The homogeneous of active component distributes and it is wished during propagating materials is handled sticking on the seed.Processing can be from comprising formulations of active ingredients film (seed dressing) at plant propagation material such as seed, can recognize seed size and/or shape originally this moment, be varied to intermediateness (as lining), become then thicker film (such as with the different materials of many layers (such as, carrier such as clay; Different preparations such as other active component; Polymer; And colouring agent) granulation), can not recognize seed shape and/or size originally this moment again.

An aspect of of the present present invention comprises active component is applied on the plant propagation material in the target mode, comprises being positioned described active component on the whole plants propagating materials or only being positioned on its part, only comprises on one-sided or on the one-sided part.Those of ordinary skills can understand these application processes from information known in the art and the specification from be provided in EP954213B1 and WO06112700.

Combined administration described herein is also comprised the plant propagation material that protection is crossed with combined treatment of the present invention to plant propagation material; place around the seed of pesticide-treated by the particle that one or more is contained agricultural chemicals; wherein the amount of agricultural chemicals is: comprise the agricultural chemicals of effective dose altogether through the seed of pesticide-treated and the particle that contains agricultural chemicals, and the described agricultural chemicals dosage that comprises in the seed of pesticide-treated is less than or equal to the maximum non-plant toxicity dosage of described agricultural chemicals.Above-mentioned technology is known in this area, particularly in WO2005/120226.

The combined administration of active component also is included in controlled release lining on the described seed to the seed, wherein active component is mixed in the material that discharges described active component in time.The example of controlled release seed processing technology extensively is known in this area, and comprises polymer film, wax or the lining of other seeds, wherein described reactive compound can be mixed described controlled-release material or be coated between material layer, or both has concurrently.

Seed can by with the active component of at least a component (I) and at least a component (II) with the order of any hope or side by side be applied on it it is handled.

Seed treatment occurs on the unseeded seed, wording " unseeded seed " be intended to comprise be in seed results and seed for the purpose of plant germination and growth by the seed in period arbitrarily between sowing in the soil.Be included in this wording definition and handle seed during sowing is handled.

To the processing of unseeded seed and be not intended to and comprise that active component wherein is administered to those practices in the soil, but will be included in any practice of using during the planting process at seed.

Preferably, before planting seed, handle, thereby described sowing seed is pretreated by described combination.Especially, seed lining or pellet seeds are preferred in the processing of the present invention's combination.The result who handles is that the active component in the described combination adheres to seed and therefore can be used for damage by disease and insect and/or disease control.

Above-mentioned treated seed can be stored, manages, sows and tiller, and method is identical with the seed of handling through any other active component.

The present invention's combination is applicable to the plant of following crop: cereal (wheat, barley, rye, oat, corn, sweet corn, rice, Chinese sorghum, triticale and relevant crop); Beet (sugar beet and fodder beet, beet root); Leguminous plant (Kidney bean, lentil, pea, soybean, clover, trefoil, peanut); Oil is used plant (rape, leaf mustard, sunflower, rape); Cucumber plants (custard squash, cucumber, pumpkin, muskmelon, Peponidium, little custard squash); Fibre plant (cotton, flax, hemp, jute); Vegetables (spinach, lettuce, witloof, Chinese celery, corn salad, asparagus, cabbage, cauliflower, brussels sprout, broccoli, kale, turnip, pakchoi, wild cabbage, Xiao Song dish (Komatsuna), water dish (Mizuna green), celeriac, celery, leek, carrot, onion, tomato, capsicum (peppers) (bell pepper and capsicum (chilli)) potato, capsicum, eggplant); And ornamental plants (flowers, shrub, broad-leaved tree and evergreen plant are such as coniferophyte) and medicinal herbs (sweet basil, wild marjoram, parsley, thyme).Suitable especially is wheat, cotton, rape, sunflower, barley, rye, oat, triticale, sugar beet, lettuce, cauliflower, cabbage, corn and soybean; Each combination advantageously is preferred for crop corn and soybean, is advantageously used in soybean most.

Suitable target crop also comprises the genetically modified crops plant of aforementioned type.The used genetically modified crops plant of the present invention is plant or its propagating materials, method by recombinant DNA technology transforms it, thereby the toxin that they for example can the synthesis of selective effect, described toxin is for example known to toxigenic invertebrate arthropoda particularly, can obtain from bacillus thuringiensis,Bt (Bacillus thuringiensis) bacterial strain; Perhaps known from plant, such as agglutinin; Perhaps alternatively can express weeding or antifungal resistance.This toxin maybe can synthesize the example of the genetically modified plants of this toxin, is disclosed in as among EP-A-0 374 753, WO 93/07278, WO 95/34656, EP-A-0 427 529 and the EP-A-451 878, and incorporates the application by reference into.

So, disease and/or damage by disease and insect infringement are had resistance through the plant propagation material of combined treatment of the present invention; Therefore, the present invention also provides the plant propagation material of pathogen and/or damage by disease and insect resistance, its with described combined treatment and therefore at least its active component adhere on propagating materials such as the seed.

In preferred implementation of the present invention, soya seeds and genetically engineered soybean seed make up with the present invention to be handled.In addition, described soya seeds can be inoculated suitable azotobacteria bacterial strain, to promote plant growing.Preferably, seed can be inoculated effective bacterial strain prior to seeding such as rhizobium (Rhizobium spp.) or Azospirillium spp..The main effect of this bacterium is that the nitrogen in the atmosphere is fixed in the plant can utilize form.For example rhizobium form root nodule particularly preferably in plant root, and it is supported by plant, and supply nitrogen for plant as mentioned above conversely.

In another embodiment, handle the bean plant propagating materials with the plant inducer, described plant inducer is for example to derive from the living slowly rhizobium of soybean (Bradyrhizobiumjaponicum), Sinorhizobium fredii (Sinorhizobium fredii), Sinorhizobium meliloti (Sinorhizobium meliloti), the nod factor of rhizobium (Bradyrhizobiumsp.) (peanut (Arachis)) or rhizobium leguminosarum (Rhizobium leguminosarum) Kidney bean (phaseoli), broad bean (viceae) or trefoil (trifolii) biological species.

On the one hand, the invention still further relates to the present invention's combination is used with the plant of tolerance glyphosate, particularly tolerate the bean plant of glyphosate, be used to prevent and treat Asia soybean rust (soybean rust) especially.Therefore, the invention provides such method, it comprises (a) will make up the plant propagation material that (A) is applied to the tolerance glyphosate, preferred soybean propagating materials, (b) once or once above ground (i) emerge preceding, (ii) emerging the back or (iii) (i) with (ii) composition pesticide (B) is applied to gained plant, plant part and/or its place with having concurrently, condition is that combination (A) comprises in first kind of embodiment of the present invention defined (I) and (II); And composition pesticide (B) comprises glyphosate.

Usually, comprise the composition of glyphosate,, use with the ratio of 960g ae/ha if only use once; If use twice, ratio can be 1200-1680g ae/ha.Ratio and application times change according to actual conditions.Preferably, described composition (B) respectively with 960,720 and the rate of application of 400g ae/ha use three times.

In one embodiment, the present invention's control, prevention or processing yam bean layer rust (Phakopsora pachyrhizi) and/or P.meibomiae, particularly yam bean layer rust.

The present invention's combination can also comprise the salt of alkali metal, alkaline earth metal, metal or ammonium.Nitrate, phosphate, sulphate, chloride and the carbonate of alkali metal, alkaline earth metal or ammonium salt, particularly sodium, potassium, ammonium, magnesium and the calcium of preferred zinc chloride and inorganic acid.

Thereby the present invention's combination can comprise nutrition and the health that micronutrient helps plant and/or plant propagation material in addition.Suitable micronutrient includes, but not limited to chlorine (Cl), zinc (ZN), boron (B), copper (Cu), iron (Fe), manganese (Mn) or molybdenum (Mo).Micronutrient can provide with chelated forms.

Germinate and soil and weather condition of growth according to the condition of concrete plant propagation material to be processed, its storage, its expection, the present invention's combination can comprise one or more additive of wide spectrum.These additives include, but not limited to uv-protecting group, pigment; dyestuff, incremental agent be such as flour, dispersant, excipient; antifreeze, preservative, herbicides and safeners; the seed safety agent, seed conditioner, micronutrient; fertilizer, biocontrol agent, surfactant; chelating agent, plasticizer, colouring agent; brightener, emulsifier, flowable is such as calcium stearate; talcum and leech soil; coalescent, defoamer, wetting agent; thickener, wax, bactericide; insecticide, agricultural chemicals and filler are such as cellulose; the glass fibre element; clay; kaolin; talcum; the bark of powdered (for example, pesudotsuga taxifolia skin or alder bark); calcium carbonate and wood chip and smell corrigent.General excipient comprises the mineral matter of segmentation, and such as float stone, attapulgite, bentonite, high mountain range zeolite, diatomite and other clays, the diatomite adsorbant of modification, charcoal, leech soil, the organic substance of segmentation is such as bog moss, wood powder etc.These additives are commercially available and be known in this area.

Single pesticide activity component can have activity in more than a kind of disease control field, for example, a kind of agricultural chemicals can have fungicide, insecticide and nematocide activity.Especially, Aldicarb is known insecticide, miticide and nematocide activity, and hundred mu knownly have Insecticides (tech) ﹠ Herbicides (tech), fungicide and nematocide activity, and probenazole and captan can provide nematocide and fungicide activity.In addition, fungicide also can have the growth regulating effect, for example, and the known demonstration PGR effect of Tebuconazole (with other triazole type).

The weight ratio of selecting active compound component is to provide required effect such as synergistic effect.Usually, described weight ratio can be according to existing how many active components to change in concrete active component and the combination.Usually, under the situation that described combination is made up of three kinds of active components, weight ratio between any two kinds of compositions, independently of one another, be 100: 1-1: 100, comprise 99: 1,98: 2,97: 3,96: 4,95: 5,94: 6,93: 7,92: 8,91: 9,90: 10,89: 11,88: 12,87: 13,86: 14,85: 15,84: 16,83: 17,82: 18,81: 19,80: 20,79: 21,78: 22,77: 23,76: 24,75: 25,74: 26,73: 27,72: 28,71: 29,70: 30,69: 31,68: 32,67: 33,66: 34,65: 45,64: 46,63: 47,62: 48,61: 49,60: 40,59: 41,58: 42,57: 43,56: 44,55: 45,54: 46,53: 47,52: 48,51: 49,50: 50,49: 51,48: 52,47: 53,46: 54,45: 55,44: 56,43: 57,42: 58,41: 59,40: 60,39: 61,38: 62,37: 63,36: 64,35: 65,34: 66,33: 67,32: 68,31: 69,30: 70,29: 71,28: 72,27: 73,26: 74,25: 75,24: 76,23: 77,22: 78,21: 79,20: 80,19: 81,18: 82,17: 83,16: 84,15: 85,14: 86,13: 87,12: 88,11: 89,10: 90,9: 91,8: 92,7: 93,6: 94,5: 95,4: 96,3: 97,2: 98 to 1: 99.Preferred weight ratio between any two kinds of components preferably 75: 1-1: 75, be more preferably 50: 1-1.50, particularly 25: 1-1: 25, advantageously 10: 1-1: 10, such as 5: 1-1: 5.

The rate of application of described combination is according to the concrete active component in for example type of service, agrotype, the described combination, plant propagation material type (if suitable) and change, but make the active component in the described combination provide the effective dose of required humidification (such as the disease or the extermination of disease and insect pest), this can be determined by test.

To blade face and soil treatment, rate of application can be 0.05 to 3kg per hectare (g/ha) active component usually.The component (I) that rate of application is 50-1000, preferred 75-500, particularly 100-300g/ha is used on suitable blade face; And 50-1000, the component (II) of preferred 250-750g/ha.

To seed treatment, rate of application can be 0.5 active component to the 1000g/100kg seed usually.The example tendency of seed treatment rate of application is 5-100, preferred 10-50, particularly 12-25, the component of g/100kg seed (I); With 0.5-10, preferred 0.75-7, particularly 1-5, the component of g/100kg seed (II).

Described component (I) or (II) and any other agricultural chemicals can be with respective pure form, promptly as for example solid active agent of specified particle diameter, at least a assistant agent (auxiliary) (being also referred to as auxiliary agent (adjuvants)) of routine is such as incremental agent for example solvent or solid carrier in perhaps preferred and the preparation technique, or surface active cpd (surfactant) is used for the present invention with dosage form together.Usually, described compound (I) and (II) be form with preparation compositions of one or more conventional formulation assistant agents.

So compound (I) and combination (II) are used with dosage form usually.Described compound (I) and (II) can be side by side or with short intervals as sequentially being applied to the place that needs control on the same day, optionally with other carrier, surfactant or formulation art conventional use other shortly use auxiliary agent and use.In a preferred implementation, (I) He (II) use simultaneously.

Under compound (I) and situation about (II) in the present invention, using simultaneously, they can be used as the composition that comprises (I), (II) and use, (I) and (II) can each obtain and be mixed together (be called bucket mixes, promptly execute, spray meat soup or slurry) in the case since the preparation that separates source, randomly with other agricultural chemicals, perhaps (I) and (II) can be used as unitary agent mixture source and obtain (being called premix, concentrate, preparation compound (or product)), and randomly be mixed together with other agricultural chemicals.

In one embodiment, the present invention's combination is used as composition.

Therefore, the present invention is a kind of composition, and it comprises as (I) of active component and (II) and other optional agricultural chemicals, and one or more optional conventional formulation assistant agents, and it can be that bucket mixes or a premix composition form.

In a kind of preferred implementation of the present invention, below combination: (I) Fluoxastrobin and (II) formononetin or its salt or ester; (I) Fluoxastrobin and thiophene worm piperazine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M and thiophene worm piperazine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, metalaxyl and thiophene worm piperazine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and thiophene worm piperazine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and thiophene worm piperazine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin, nitrile bacterium azoles and thiophene worm piperazine and (II) formononetin or its salt or ester; (I) Fluoxastrobin and Avermectin and (II) formononetin or its salt or ester; (I) fludioxonil, Metalaxyl-M, Avermectin and thiophene worm piperazine and (II) formononetin or its salt or ester; (I) Avermectin and thiophene worm piperazine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M and (II) formononetin or its salt or ester; (I) Fluoxastrobin and thiophene worm piperazine and (II) formononetin or its salt or ester; (I) thiophene worm piperazine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M and Imidacloprid and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, metalaxyl and Imidacloprid and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and Imidacloprid and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and Imidacloprid and (II) formononetin or its salt or ester; (I) thiophene worm amine and (II) formononetin or its salt or ester; (I) Fluoxastrobin and thiophene worm amine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M and thiophene worm amine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, metalaxyl and thiophene worm amine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and thiophene worm amine and (II) formononetin or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and thiophene worm amine and (II) formononetin or its salt or ester; (I) thiophene worm amine and prothioconazoles and (II) formononetin or its salt or ester; (I) thiophene worm amine, fluoxastrobin and prothioconazoles and (II) formononetin or its salt or ester; (I) thiophene worm amine, Tebuconazole, triazoxide and prothioconazoles and (II) formononetin or its salt or ester; (I) Imidacloprid and prothioconazoles and (II) formononetin or its salt or ester; (I) thiophene worm piperazine, Tebuconazole and fludioxonil and (II) formononetin or its salt or ester; (I) Imidacloprid and carboxin and (II) formononetin or its salt or ester; (I) thiophene worm piperazine, tefluthrin, Fluoxastrobin and Tebuconazole and (II) formononetin or its salt or ester; (I) Imidacloprid and Tebuconazole and (II) formononetin; Provide with premix composition (or mixture) form, wherein formononetin is natural generation or synthesized form.

In another kind of preferred implementation of the present invention, below combination: (I) Fluoxastrobin and (II) genistein or its salt or ester; (I) Fluoxastrobin and thiophene worm piperazine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M and thiophene worm piperazine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, metalaxyl and thiophene worm piperazine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and thiophene worm piperazine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and thiophene worm piperazine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin, nitrile bacterium azoles and thiophene worm piperazine and (II) genistein or its salt or ester; (I) Fluoxastrobin and Avermectin and (II) genistein or its salt or ester; (I) fludioxonil, Metalaxyl-M, Avermectin and thiophene worm piperazine and (II) genistein or its salt or ester; (I) Avermectin and thiophene worm piperazine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M and (II) genistein or its salt or ester; (I) Fluoxastrobin and thiophene worm piperazine and (II) genistein or its salt or ester; (I) thiophene worm piperazine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M and Imidacloprid and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, metalaxyl and Imidacloprid and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and Imidacloprid and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and Imidacloprid and (II) genistein or its salt or ester; (I) thiophene worm amine and (II) genistein or its salt or ester; (I) Fluoxastrobin and thiophene worm amine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M and thiophene worm amine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, metalaxyl and thiophene worm amine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and thiophene worm amine and (II) genistein or its salt or ester; (I) Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and thiophene worm amine and (II) genistein or its salt or ester; (I) thiophene worm amine and prothioconazoles and (II) genistein or its salt or ester; (I) thiophene worm amine, fluoxastrobin and prothioconazoles and (II) genistein or its salt or ester; (I) thiophene worm amine, Tebuconazole, triazoxide and prothioconazoles and (II) genistein or its salt or ester; (I) Imidacloprid and prothioconazoles and (II) genistein or its salt or ester; (I) thiophene worm piperazine, Tebuconazole and fludioxonil and (II) genistein or its salt or ester; (I) Imidacloprid and carboxin and (II) genistein or its salt or ester; (I) thiophene worm piperazine, tefluthrin, Fluoxastrobin and Tebuconazole and (II) genistein or its salt or ester; (I) Imidacloprid and Tebuconazole and (II) genistein or its salt or ester; Provide with premix composition (or mixture) form, wherein genistein is natural generation or synthesized form.

In a kind of preferred embodiment of the present invention, below combination: (I) Metalaxyl-M and fludioxonil and (II) formononetin; (I) probenazole, Metalaxyl-M and fludioxonil and thiophene worm piperazine and (II) formononetin; (I) probenazole, Metalaxyl-M, Fluoxastrobin and fludioxonil and (II) formononetin; (I) probenazole, Metalaxyl-M, Fluoxastrobin, fludioxonil and thiophene worm piperazine and (II) formononetin; (I) Metalaxyl-M and fludioxonil and (II) genistein; (I) probenazole, Metalaxyl-M and fludioxonil and thiophene worm piperazine and (II) genistein; (I) probenazole, Metalaxyl-M, Fluoxastrobin and fludioxonil and (II) genistein; (I) probenazole, Metalaxyl-M, Fluoxastrobin, fludioxonil and thiophene worm piperazine and (II) genistein; Provide with premix composition (or mixture) form.

The example that is used for the blade face system type of premix composition is:

GR: granule

WP: wetting powder

WG: water-dispersible granules (pulvis)

SG: water-soluble granule

SL: solvable dense dose

EC: missible oil

EW: oil in water emulsion

ME: microemulsion

SC: suspension concentrates

CS: micro-capsule suspension

OD: the oil-based suspension concentrate and

SE: suspension emulsion.

And the example that is used for the seed treatment system type of premix composition is:

WS: slurry kind of processing water-dispersible powder

LS: seed treatment liquor

ES: seed treatment emulsion

FS: seed treatment suspension concentrates

WG: water-dispersible granules and

CS: micro-capsule suspension.

The example that is applicable to the formulation of barrel mixing composition is solution, dilution emulsion, suspending agent or its mixture, and pulvis.

Similar with the character of composition, application process as blade face, dipping, spraying, to atomize, dust, broadcast sowing, be covered or pour into be to select according to destination object and main environment.

One or more premix compositions that the bucket mixing composition normally uses solvent (for example water) dilution to comprise different agricultural chemicals and optional other assistant agent prepare.

Suitable carrier and auxiliary agent can be solid or liquid and be normally used material in the preparation technique, for example natural or regeneration mineral matter, solvent, dispersant, wetting agent, tackifier, thickener, adhesive or fertilizer.

Preparation prepares with known method, and for example by with active component and incremental agent such as solvent, solid carrier with when suitable, surface active cpd (surfactant) mixes equably and/or grinds.

The suitable solvent is: aromatic hydrocarbon, the cut that preferably comprises 8 to 12 carbon atoms, as xylene mixture or the naphthalene that is substituted, phthalic acid ester, such as dibutyl phthalate or dioctyl phthalate, aliphatic hydrocarbon, such as cyclohexane or paraffin, pure and mild glycol and ether thereof and ester, such as ethanol, ethylene glycol, glycol monoethyl ether or ethylene glycol monoethyl ether, ketone is such as cyclohexanone, intensive polar solvent, such as the N-N-methyl-2-2-pyrrolidone N-, methyl-sulfoxide or dimethyl formamide, and vegetable oil or epoxidized vegetable oil are such as epoxidation cocoa butter or soybean oil; Perhaps water.

The solid carrier that for example is used for pulvis and dispersion powder is the natural minerals filler normally, such as calcite, talcum, kaolin, montmorillonite or attapulgite.For improving physical property, can also add the adsorbability polymer of high dispersive silicic acid or high dispersive.Suitable particle adsorptive support is the porous type, for example float stone, brickbat, sepiolite or bentonite, and the carrier of suitable non-adsorptivity is, for example calcite or sand.In addition, can use the material of many granular in advance inorganic or organic quality, for example, particularly dolomite or comminuted plants residue.

According to the character of the active compound component of wanting preparation, suitable surface active cpd is nonionic, cation and/or the anion surfactant with well emulsify, dispersion and moistening character.Wording " surfactant " also is understood that to comprise surfactant mixtures.

Particularly advantageous short the use natural or synthetic phospholipid that auxiliary agent also has cephalin and lecithin series, for example phosphatidyl-ethanolamine, phosphatidylserine, phosphatidyl glycerol and lysolecithin.

Usually, a bucket mix formulation that is used for blade face or soil application comprises 0.1 to 20%, 0.1 to 15% active compound component particularly, (comprise with 99.9 to 80%, particularly 99.9 to 85% solid or liquid assistant agent, solvent for example, such as water), wherein said assistant agent can be based on the surfactant of 0 to 20%, particularly 0.1 to 15% amount of described bucket mix formulation.

Usually, the premix formulations that is used for foliage applying comprises 0.1 to 99.9%, 1 to 95% active compound component particularly, (comprise with 99.9 to 0.1%, particularly 99 to 5% solid or liquid assistant agent, solvent for example, such as water), wherein said assistant agent can be based on the surfactant of 0 to 50%, particularly 0.5 to 40% amount of described premix formulations.

Normally, be used for that a bucket mix formulation that seed treatment uses comprises 0.25 to 80%, 1 to 75% active compound component particularly, (comprise with 99.75 to 20%, particularly 99 to 25% solid or liquid assistant agent, solvent for example, such as water), wherein said assistant agent can be based on the surfactant of 0 to 40%, particularly 0.5 to 30% amount of described bucket mix formulation.

Normally, be used for that premix formulations that seed treatment uses comprises 0.5 to 99.9%, 1 to 95% active compound component particularly, (comprise with 99.5 to 0.1%, particularly 99 to 5% solid or liquid assistant agent, solvent for example, such as water), wherein said assistant agent can be based on the surfactant of 0 to 50%, particularly 0.5 to 40% amount of described premix formulations.

Although commercial product is concentrate (a for example premix composition (preparation)) by preparation preferably, the terminal use uses dilution preparation (for example bucket mixing composition) usually.

Preferred seed treatment premix formulations is moisture suspension concentrates.Described preparation can use conventional treatment technology and equipment such as fluidization, roller-crushing mill method, rotor-stator seed processing machine and drum-type lining machine to be applied to seed.Also can use other method such as spouted bed.Seed can select the footpath in advance before lining.After the lining, seed is dried usually and is transferred to machine choosing footpath, choosing footpath subsequently.Said method is as known in the art.

By spraying, perfusion or soak, directly or through using the said preparation can treatment of plant propagation material and protect its antagonism dilutedly for example from the infringement of pathogen.

Active component combined feature of the present invention is such fact, promptly they by the good especially tolerance of plant and to the environment friend and.

Each active component combination of the present invention is particularly conducive to the processing of plant propagation material.

In a preferred embodiment, each combination of the present invention is the treatment compositions of treatment of plant propagation material preferred seed.

In various aspects of the present invention and embodiment, " comprising basically " and to change be " comprising " and the preferred form of expression that changes thereof, and " by ... form " and change and be " substantially by ... form " and the preferred form of expression that changes.

Claims (16)

1. pesticide combination, it comprises at least two kinds of active ingredient components and one or more optional conventional formulation assistant agents, and wherein component (I) comprises at least a compound or its salt or ester, is selected from Fluoxastrobin, Difenoconazole, fluoxastrobin, Tebuconazole, probenazole, oxime bacterium ester, formula I _I-I _IVNeighbour-cyclopropyl-carbanilide,

Wherein

R _xBe trifluoromethyl or difluoromethyl and

R _yBe hydrogen or methyl; Or the dynamic isomer of this compound;

Formula (CC) compound

Pyraclostrobin, tmtd, triticonazole, prothioconazoles, Avermectin, thiophene worm amine, Bt product, fluorine worm nitrile, λ-cyhalothrin, pleocidin, thiophene worm quinoline, thiophene worm piperazine, the two prestige of sulphur, tefluthrin, paclobutrazol, Cyproconazole, anti-ester, uniconazole P, gibberellic acid, GA3, GA4+GA7, Acibenzolar, irritated pathogenicity proteins;

And component (II) comprises the isoflavones of at least a natural generation or synthesized form.

2. according to the combination of claim 1, wherein (I) also comprises one or more fungicide, insecticide, nematocide, miticide, invertebrate poison, plant growth regulator or plant activator.

3. according to each combination in claim 1 or the claim 2, wherein (II) is selected from the formononetin of natural generation or synthesized form and isoflavones and the salt and the ester of genistein.

4. according to each combination among the claim 1-3, wherein component (II) comprises genistein and salt and ester.

5. according to each combination among the claim 1-3, wherein component (II) comprises formononetin and salt and ester.

6. according to each combination among the claim 1-5, it is the form of the composition pesticide of treatment of plant propagation material.

7. according to each combination in the claim 1 to 6, wherein (I) is Fluoxastrobin and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin and thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M and thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, metalaxyl and thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin, nitrile bacterium azoles and thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin and Avermectin and (II) be formononetin or its salt or ester; (I) be fludioxonil, Metalaxyl-M, Avermectin and thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be Avermectin and thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin and thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be thiophene worm piperazine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M and Imidacloprid and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, metalaxyl and Imidacloprid and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and Imidacloprid and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and Imidacloprid and (II) be formononetin or its salt or ester; (I) be thiophene worm amine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin and thiophene worm amine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M and thiophene worm amine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, metalaxyl and thiophene worm amine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and thiophene worm amine and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and thiophene worm amine and (II) be formononetin or its salt or ester; (I) be thiophene worm amine and prothioconazoles and (II) be formononetin or its salt or ester; (I) be thiophene worm amine, fluoxastrobin and prothioconazoles and (II) be formononetin or its salt or ester; (I) be thiophene worm amine, Tebuconazole, triazoxide and prothioconazoles and (II) be formononetin or its salt or ester; (I) be Imidacloprid and prothioconazoles and (II) be formononetin or its salt or ester; (I) be thiophene worm piperazine, Tebuconazole and fludioxonil and (II) be formononetin or its salt or ester; (I) be Imidacloprid and carboxin and (II) be formononetin or its salt or ester; (I) be thiophene worm piperazine, tefluthrin, Fluoxastrobin and Tebuconazole and (II) be formononetin or its salt or ester; (I) be Imidacloprid and Tebuconazole and (II) be formononetin or its salt or ester; (I) be Fluoxastrobin and (II) be genistein or its salt or ester; (I) be Fluoxastrobin and thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M and thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, metalaxyl and thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin, nitrile bacterium azoles and thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin and Avermectin and (II) be genistein or its salt or ester; (I) be fludioxonil, Metalaxyl-M, Avermectin and thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be Avermectin and thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M and (II) be genistein or its salt or ester; (I) be Fluoxastrobin and thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be thiophene worm piperazine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M and Imidacloprid and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, metalaxyl and Imidacloprid and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and Imidacloprid and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and Imidacloprid and (II) be genistein or its salt or ester; (I) be thiophene worm amine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin and thiophene worm amine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M and thiophene worm amine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, metalaxyl and thiophene worm amine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, nitrile bacterium azoles and thiophene worm amine and (II) be genistein or its salt or ester; (I) be Fluoxastrobin, fludioxonil, Metalaxyl-M, Avermectin and thiophene worm amine and (II) be genistein or its salt or ester; (I) be thiophene worm amine and prothioconazoles and (II) be genistein or its salt or ester; (I) be thiophene worm amine, fluoxastrobin and prothioconazoles and (II) be genistein or its salt or ester; (I) be thiophene worm amine, Tebuconazole, triazoxide and prothioconazoles and (II) be genistein or its salt or ester; (I) be Imidacloprid and prothioconazoles and (II) be genistein or its salt or ester; (I) be thiophene worm piperazine, Tebuconazole and fludioxonil and (II) be genistein or its salt or ester; (I) be Imidacloprid and carboxin and (II) be genistein or its salt or ester; (I) be thiophene worm piperazine, tefluthrin, Fluoxastrobin and Tebuconazole and (II) be genistein or its salt or ester; (I) be Imidacloprid and Tebuconazole and (II) be genistein or its salt or ester.

8. the method for control or infringement of prevention pathogen or damage by disease and insect infringement in plant propagation material, plant, plant part and/or a late period growing plants organ, it comprises to described plant, plant part or its environment uses the defined combination in each as claim 1-7.

9. the method for a protective plant propagating materials, plant, plant part and/or growing plants organ antagonism pathogen infringement in late period or damage by disease and insect infringement, it is by each defined combination in described plant, plant part or its environment are used as claim 1-7.

10. method of improving the growth characteristics of plant, it comprises each defined combination in described plant and/or plant part are used as claim 1-7.

11. each method according to Claim 8-10 is wherein used as claim 1-7 in each defined (I) and (II) simultaneously.

12. each method according to Claim 8-11, wherein will as claim 1-7 in each defined combined administration to plant propagation material.

13. each method according to Claim 8-12, wherein said plant propagation material is a seed.

14. each method according to Claim 8-12, wherein said plant propagation material are the seeds of following plants: cereal (wheat, barley, rye, oat, corn, rice, Chinese sorghum, triticale and relevant crop); Beet (sugar beet and fodder beet); Leguminous plant (Kidney bean, lentil, pea, soybean); Oil plants (rape, leaf mustard, sunflower, rape); Cucumber plants (custard squash, cucumber, muskmelon); Fibre plant (cotton, flax, hemp, jute); Vegetables (spinach, lettuce, asparagus, cabbage, carrot, onion, tomato, potato, capsicum); And ornamental plants (flowers, shrub, broad-leaved tree and evergreen plant such as coniferophyte).

15. plant propagation material with each defined combined treatment among the claim 1-7.

16. according to the plant propagation material of claim 15, it is the seed of following plants: cereal (wheat, barley, rye, oat, corn, rice, Chinese sorghum, triticale and relevant crop); Beet (sugar beet and fodder beet); Leguminous plant (Kidney bean, lentil, pea, soybean); Oil plants (rape, leaf mustard, sunflower, rape); Cucumber plants (custard squash, cucumber, muskmelon); Fibre plant (cotton, flax, hemp, jute); Vegetables (spinach, lettuce, asparagus, cabbage, carrot, onion, tomato, potato, capsicum); And ornamental plants (flowers, shrub, broad-leaved tree and evergreen plant such as coniferophyte).