CN101607217B - Quantitative receiving device used for optical control solid phase extraction - Google Patents
Quantitative receiving device used for optical control solid phase extraction Download PDFInfo
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- CN101607217B CN101607217B CN2009101606408A CN200910160640A CN101607217B CN 101607217 B CN101607217 B CN 101607217B CN 2009101606408 A CN2009101606408 A CN 2009101606408A CN 200910160640 A CN200910160640 A CN 200910160640A CN 101607217 B CN101607217 B CN 101607217B
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- phase extraction
- glass tube
- solid phase
- extraction column
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Abstract
A device for fixing the volume of liquid in a solid phase extraction column includes: a glass tube receiving liquid leaking from the solid phase extraction column and a laser sensor that can detect the position of liquid level and moves up and down along the outside of the wall of the glass tube through a mechanical transmission device, wherein the lower end of the glass tube is provided with an adapter connected with an inlet of an electromagnetic valve, the other outlet of which is connected with a waste liquid bottle through a pipe. During work, the electromagnetic valve is normally closed, and the height of the liquid level is calculated according to the liquid volume needing to be detected; the laser sensor moves to a corresponding position, a leaking liquid procedure of the solid phase extraction column is started so that the liquid in the solid phase extraction column leaks into the glass tube; and when the liquid level reaches the position of the laser sensor, the sensor sends out a signal, the liquid leakage procedure of the solid phase extraction column is stopped, the electromagnetic valve is started, the liquid in the glass tube is discharged to the waste liquid bottle, and the next solid phase extraction leaking liquid operation is conducted. In this way, the steps are repeated.
Description
Technical field
The present invention relates to a kind of receiving system, especially quantitative receiving device.
Background technology
SPE (Solid-Phase Extraction is called for short SPE): be a physical extraction process that comprises liquid phase and solid phase.In the SPE process, greater than the sample mother liquor, when sample during by solid-phase extraction column, analyte is attracted to the surface of solids to solid phase to the absorption affinity of analyte, other components then with the sample mother liquor by pillar, with appropriate solvent analyte is taken off at last.
Solid phase extraction techniques is developed recently a kind of sample pretreatment technology of getting up, by liquid-solid extraction and column liquid chromatographic technology in conjunction with development, be mainly used in separation, the purifying and concentrated of sample, with traditional liquid-liquid extraction method compare the rate of recovery that can improve analyte, more effective analyte is separated the sample pretreatment process that reduces with interfering component, simple to operate, save time advantage such as laborsaving.Be applied in fields such as medicine, food, environmental protection, commodity inspection, residues of pesticides widely.
In the food samples testing process, SPE is a very key link, directly influence the reliability of testing result, in this process, the constant volume of solid phase pillar is its key link, the volume that needs liquid in the strict control pillar, and guarantee that the solid phase pillar is in moisture state, so, need to repeat the liquid feeding leakage, manually-operated is dry as dust, and does not have reproducibility.In order to use manpower and material resources sparingly, to press for the automation that realizes sample and handle.
Summary of the invention
For solving an above-mentioned difficult problem, this patent discloses a kind of quantitative receiving device used for optical control solid phase extraction.This device can be reported to the police when the waste liquid volume reaches predetermined value, and closes SPE leakage program, realizes the automatic control of constant volume liquid volume.The concrete structure of this device is:
A kind of quantitative receiving device used for optical control solid phase extraction: comprise an acceptance from the leak down glass tube of liquid of solid-phase extraction column, there is adapter the glass tube lower end, and described adapter and electromagnetic valve entrance join, and the outlet of magnetic valve is connected with waste liquid bottle by pipeline.The laser sensor that can detect liquid level position can move up and down along the glass tube walls outside by mechanical driving device; During work, magnetic valve is normally closed, and the liquid volume of Jian Ceing calculates liquid level as required; Laser sensor moves to the relevant position, open solid-phase extraction column leakage program, liquid is bled in the glass tube, when liquid level arrived the laser sensor position, sensor sent signal, stops solid-phase extraction column leakage program, opens solenoid valve, liquid in the glass tube is entered waste liquid bottle, after liquid enters waste liquid bottle fully, closed electromagnetic valve.
Further, described adapter is the tetrafluoro adapter.
Description of drawings
Fig. 1 is quantitative accepting device structural representation;
Fig. 2 is quantitative receiving device structural representation among the present invention.
The specific embodiment
As shown in Figure 1, quantitative receiving device used for optical control solid phase extraction: comprise a transparent glass tube 3, be used for receiving solid-phase extraction column 1 liquid that leaks down, glass tube 3 is fixed on the fixture 2 by support 4, regulates glass tube 3 vertical as for horizontal plane after fixing.The glass tube lower end has adapter, the adapter that uses among the present invention is tetrafluoro adapter 6, and link to each other with the inlet of magnetic valve on being fixed on fixture 2 by adapter 6, electromagnetic valve outlet is provided with adapter 7, adapter 7 is connected with flexible pipe 8, and can pass through flexible pipe 8, liquid is entered in the waste liquid bottle 9.The glass tube outside also is provided with the laser sensor 5 that can measure liquid level, and this sensor is realized the vertical motion up and down perpendicular to horizontal plane by external transmission device (not showing among the figure).
In the test, at first, having calculated needs to leak down liquid volume in the solid-phase extraction column, and calculates liquid level in the glass tube 3 according to these data.Laser sensor 5 drives by external transmission device, arrive the specified altitude assignment position, close magnetic valve, open SPE leakage program, liquid bleeds in the glass tube 3 in the SPE, when liquid level rises to sensing station, sensor sends signal, SPE leakage stop, and magnetic valve is opened, liquid in the glass tube is drained in the waste liquid bottle, realizes one time the leakage constant volume.After liquid in the glass tube flows in the waste liquid bottle fully, closed electromagnetic valve, a SPE leakage EP (end of program).And can begin next SPE leakage program, so circulation.
Claims (2)
1. quantitative receiving device used for optical control solid phase extraction, comprise that an acceptance is from the leak down glass tube of liquid of solid-phase extraction column, there is adapter the glass tube lower end, described adapter and electromagnetic valve entrance join, the outlet of magnetic valve is connected with waste liquid bottle by pipeline, the laser sensor that can detect liquid level position is arranged on the vial wall outside, can move up and down along the glass tube walls outside by mechanical driving device; During work, magnetic valve is normally closed, and the liquid volume of Jian Ceing calculates liquid level as required; Laser sensor moves to the relevant position, open solid-phase extraction column leakage program, liquid is bled in the glass tube, when liquid level arrives the laser sensor position, sensor sends signal, stops solid-phase extraction column leakage program, opens solenoid valve, liquid in the glass tube is entered waste liquid bottle, carry out next SPE leakage operation; So circulation.
2. according to quantitative receiving device used for optical control solid phase extraction described in the claim 1, it is characterized by: described adapter is the tetrafluoro adapter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101606408A CN101607217B (en) | 2009-07-20 | 2009-07-20 | Quantitative receiving device used for optical control solid phase extraction |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101606408A CN101607217B (en) | 2009-07-20 | 2009-07-20 | Quantitative receiving device used for optical control solid phase extraction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101607217A CN101607217A (en) | 2009-12-23 |
| CN101607217B true CN101607217B (en) | 2010-12-01 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009101606408A Expired - Fee Related CN101607217B (en) | 2009-07-20 | 2009-07-20 | Quantitative receiving device used for optical control solid phase extraction |
Country Status (1)
| Country | Link |
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| CN (1) | CN101607217B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107367422A (en) * | 2017-08-07 | 2017-11-21 | 胡国良 | Extract leakage detection method and abstraction instrument |
| CN110893289B (en) * | 2018-09-12 | 2021-07-06 | 中世沃克(天津)科技发展股份有限公司 | Automatic solid phase extraction device |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201096675Y (en) * | 2007-11-06 | 2008-08-06 | 河南理工大学 | Continuous fluid-solid phase micro extraction device |
| CN101308067A (en) * | 2008-07-11 | 2008-11-19 | 福州大学 | Liquid phase micro- extraction on-line preliminary treatment device for capillary pipe electrophoresis-ampere detector and its usage method |
-
2009
- 2009-07-20 CN CN2009101606408A patent/CN101607217B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201096675Y (en) * | 2007-11-06 | 2008-08-06 | 河南理工大学 | Continuous fluid-solid phase micro extraction device |
| CN101308067A (en) * | 2008-07-11 | 2008-11-19 | 福州大学 | Liquid phase micro- extraction on-line preliminary treatment device for capillary pipe electrophoresis-ampere detector and its usage method |
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| Publication number | Publication date |
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| CN101607217A (en) | 2009-12-23 |
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Granted publication date: 20101201 Termination date: 20170720 |