CN101601692A - The double-face external patch of treatment night sweat - Google Patents
The double-face external patch of treatment night sweat Download PDFInfo
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- CN101601692A CN101601692A CNA2008100534910A CN200810053491A CN101601692A CN 101601692 A CN101601692 A CN 101601692A CN A2008100534910 A CNA2008100534910 A CN A2008100534910A CN 200810053491 A CN200810053491 A CN 200810053491A CN 101601692 A CN101601692 A CN 101601692A
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- night sweat
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Abstract
The present invention relates to a kind of double-face external patch that can treat night sweat.The pharmaceutical preparation that the double-face external patch that is used for the treatment of night sweat disclosed by the invention is made up of the pharmaceutic adjuvant of 2%～100% Chinese medicine extract and 98%～0%, Cinnabaris 1～5 weight portion wherein, Galla Chinensis 1～15 weight portion.Chinese herbs paste disclosed by the invention is divided into five layers altogether, the intermediate layer is the reasonable base material of breathability, and at the two sides of base material separate application gluing sample, one side is the more intense PUR of adhibit quality, during use, throw off the hot melt adhesive layer protecting film and be attached on the underwear position at health care of body position; The reasonable water-soluble glue sample of release (pastille) in the another side coating of base material; throw off the protecting film of Drug Storage outside during use; aim at the health care of body position; utilize body skin body temperature heat; excite the absorption of drug storehouse layer mid and far infrared powder and release energy effective health-care components contact body surface in the drive Drug Storage, and formation medicine microecological environment; to guarantee that the medicine percutaneous absorbs, and reaches prevention and therapeutic purposes.
Description
Technical field:
The present invention relates to a kind of external use plaster of double faced adhesive tape sample, a kind of double-face external patch that can treat night sweat.
Background technology:
Existing commercially available various Chinese herbs pastes generally all are to be attached on the skin, and compliance and the various pressure-sensitive to the glue sample requires all than higher, even so still there is the easy irritated crowd of minority that untoward reaction is arranged like this.The used glue sample of existing patch probably is divided into two kinds in hot melt glue sample and water-soluble glue sample, PUR stickup force rate is stronger, be difficult for water-permeable and air permeable, the stickup time is long more, people's skin is easy more feels uncomfortable, and being easy to uncomfortable feeling when peeling off, heating-up temperature is unsuitable for the coating of Chinese medicine than higher during coating.The hydrosol is higher than PUR with the compliance of skin, and is permeable and breathability is relatively good, but adhibit quality is poor, comes unstuck easily, especially at weather in the heat.Hydrosol heating-up temperature is lower, and water content is higher than PUR, is easier to Chinese medicine extract mixing ratio, and it is a lot of easily that coating is wanted relatively.In conjunction with the pluses and minuses of two brood lac samples, the present invention has designed a kind of external use plaster that can stick on the underclothes, both can reduce the anaphylaxis of glue sample, can increase crowd's the suitability again.The scope of application and the practicality of external use plaster have been enlarged.
Existing health promoting clothes probably is divided into two kinds of forms, a kind of is that underwear is made as sandwich, be placed in the interlayer of underskirt after packing into the mixture of medicine in the medicated bag, be placed on the different acupuncture points according to the medicated bag of different diseases different formulations, also have exactly medicated powder or far-infrared powder uniform distribution be placed in clothes intermediary cotton layer similar to it, be covered with netted sewing thread on the clothes, the medicated powder layer is fixed, above this health-care underclothes, be inconvenient to carry, weak curative effect such as is inconvenient to clean at shortcoming.Be difficult for being accepted by masses.Another kind is first kind a development form, and it is made lamellar with medicine and is placed in the cloth that heating wire should be arranged, and heating wire is connected with the instrument of a series of help treatments such as vibrating motor, modulator, by reaching health-care effect with upper type.It has certain service life and certain danger, need electricity consumption, it is not very convenient using and carrying, the present invention has designed a kind of two-sided patch, as long as stick on the fixed position on the medicated clothing next to the shin during use, Drug Storage is aimed at the corresponding treatment acupuncture point, the two-sided patch of this kind uses and is very convenient to carry, do not exist cementing property of patch commonly used poor, the meeting pollution clothes, the human body practicality is smaller comparatively speaking, two-sided patch of the present invention is directly to be attached on the medicated clothing, closely do not contact for a long time with skin, both solved the problem that the water-soluble glue sample is pasted not strongly easily because of perspiring, alleviated again because of the long-time and isolated skin allergy that causes of air, reduced the requirement to glue sample pressure sensitive, the irritated crowd's of commute the suitability is wider.The health-care underclothes of comparing, this patch is easy to carry, can paste repeatedly, and it is convenient to change its paste section bit comparison, plaster is taken off getting final product cleaning clothes, cleans very conveniently, can renew plaster at any time, changes very convenient.Suitable crowd is more extensive, and compliance is very good.Reduced application limit greatly.
Summary of the invention
The object of the invention is to remedy all deficiencies of common glue sample patch, reduces it to the selectivity of glue sample with to the zest of skin, reduces its side effect as far as possible, just can reach treatment and health care in daily routines at ordinary times, has also increased crowd's the suitability.
Purpose of the present invention is achieved through the following technical solutions:
Above-described two-sided patch is more frivolous; this external patch is divided into five layers altogether; the intermediate layer is the reasonable base material of breathability; at the two sides of base material separate application gluing sample; one side is the more intense PUR of adhibit quality; the reasonable water-soluble glue sample of release (pastille) in the another side coating of base material attaches upper protective film separately on both sides.During use, take out special-purpose patch earlier, throw off the hot melt adhesive layer protecting film and be attached on the underwear position at health care of body position, throw off the protecting film of Drug Storage outside again, aim at the health care of body position.Utilize body skin body temperature heat, excite drug storehouse layer mid and far infrared powder to absorb and release energy, drive in the Drug Storage effectively health-care components contact body surface, guarantee for forming the ecological microenvironment of medicine.
Cinnabaris is slightly cold, and goes into heart channel, the kind heat that clears away heart-fire, and receives the floating fire that stays and calms the nerves; Gallic acid is salty and cold, and property is held back, and goes into the lung kidney channel, dampness is arranged, astringes the lung, the merit of astringing intestine to stop diarrhea.Cinnabaris, Galla Chinensis are regulated the cloudy gas of cardiopulmonary kidney by SHENQUE acupoint, let out YIN-fire, and is solid cloudy smart, makes coordination between the heart and kidney, the heart-fire self-balancing, and battalion defends mediation, and space between skin and muscles is solid close, and turbid damp can be held back, and night sweat is from only.
Chinese medicine of the present invention is made by the medicinal substances extract of following weight proportion: Cinnabaris 1～5 weight portion, Galla Chinensis 1～15 weight portion.The weight ratio of Drug Storage Chinese medicine and glue is 1: 1～10.
PUR among the present invention can be polyurethanes, esters of acrylic acid, isobutylene type, silicone rubber kinds etc.
Used water-soluble glue can adopt the two kinds or more of raw materials of following weight percentage ratio to make among the present invention: chitosan 1～15, gelatin 1～15, polyvinylpyrrolidone (PVP) 1～30, polyvinyl alcohol (PVA) 1～25, polyacrylic acid 1～20, Polyethylene Glycol (PEG) 1～20, sodium carboxymethyl cellulose 1～10, arabic gum 1～20, agar 1～20, sodium alginate 1～15, CBP 1～15, glycerol 1～40, propylene glycol 1～40; Other raw materials are far-infrared powder 0.05～5, penetrating agent 0.1～10, and all the other are appropriate amount of deionized water.
Used base material can be dried/wet nonwoven fabrics, artificial skin, aluminizer, medical elastic cloth, the spinning cloth of medical cotton textiles among the present invention.
Protecting film used among the present invention can be paper, polyester film, polyethylene film, polypropylene screen, polychloroethylene film, the polystyrene film through release treatment.
Penetrating agent of the present invention comprises dimethyl sulfoxide and analog: dimethyl sulfoxide (DMSO); Azone compounds: laurocapram Azone.
Chinese crude drug extraction process of the present invention is not limited to that water is carried or alcohol extraction process, also can be that water is put forward other extraction processes such as organic solvent extractionprocess, alcohol extraction organic solvent extractionprocess and supercritical fluid extraction; Also available extrusion modling of the preparation technology of patch or blade coating moulding process.Gel adhesive of the present invention can be made arbitrary shape.
Preparation technology: hot-fusible pressure-sensitive adhesive is coated on the base material, and multiple protecting film is again in base material reverse side coating Drug Storage, cold drying patent medicine film, multiple Drug Storage protecting film, stamping-out, the packing of product.
The preparation of Drug Storage: two or more raw materials of above-mentioned water-soluble glue are added in the agitator tank, add a certain amount of water, heat to 50 ℃, after treating that the glue sample stirs, be cooled to 40 ℃ and add drug extract, the penetrating agent that extracts in advance, add far-infrared powder again, add water until the viscosity that is fit to coating.
Description of drawings
Accompanying drawing 1 is the audio-visual picture of analysing and observe to above-described two-sided patch; be five layers altogether; the base material of intermediate layer for being fit to; the one side of base material is the more intense pressure sensitive adhesive of adhibit quality (this layer sticks on the underwear); another side at base material is drug storehouse layer (this laminating applies skin), the both sides suitable protecting film of respectively doing for oneself.
The specific embodiment
Below example by the specific embodiment, foregoing of the present invention is described in further detail, embodiment only is indicative, means that never it limits the scope of the invention by any way.But do not breaking away under the above-mentioned technological thought situation of the present invention, the various replacements of making according to ordinary skill knowledge and habitual means or the modification of change include within the scope of the invention.
Embodiment:
Transdermal enhancer laurocapram Azone 6kg
Water-soluble glue 5% arabic gum, 10% Polyethylene Glycol (PEG)
6% agar, 5% chitosan
74% deionized water 400kg
Effective ingredient extract 80kg
Far-infrared powder 4.8kg
Take by weighing 20kg arabic gum, 40kg Polyethylene Glycol, 24kg agar and 20kg chitosan, add a certain amount of water, in agitator, heat to 50 ℃, after treating that the glue sample stirs, stir evenly, be cooled to 40 ℃, add the effective ingredient extract 80kg, the penetrating agent laurocapram 6kg that extract in advance, add far-infrared powder 4.8kg again, moisturizing is to capacity.The medicine rubber-surfaced roll that is mixed is coated in the opposite side of the non-woven fabrics that coats hot glue in advance, will covers on the medicine glue-line through the polyester protecting film that release treatment is crossed, THICKNESS CONTROL is below 5mm.Stamping-out is carried out by specification in the sterilization back, makes patch, and coefficient of losses 15% is pressed Chinese Pharmacopoeia patch standard through quality inspection qualification rate 85%.The certified products packing.
Therapeutic effect:
Criterion of therapeutical effect: the curative effect of treatment night sweating judges whether mainly be dependent on the night sweat symptom disappears.Medication 3 days was 1 course of treatment.Concrete curative effect is divided following three grades: cure---and the night sweating symptom all disappears; Taking a turn for the better---the night sweating symptom partly disappears; Invalid---after medication 1 course of treatment, the night sweating symptom has no to disappear.
Effect: with these Drug therapy night sweating patient 15 examples, treat 1 course of treatment, wherein cure 12 examples, wherein 4 examples are through not imitating and get effect with this law with the multiple diaphoresis of controlling, and 3 examples take a turn for the better.
Claims (8)
1. treat the double-face external patch of night sweat; it is characterized in that: this external patch is divided into five layers altogether; the intermediate layer is the reasonable base material of breathability; at the two sides of base material separate application gluing sample; one side is the more intense PUR of adhibit quality; the reasonable water-soluble glue sample of release (pastille) in the another side coating of base material attaches upper protective film separately on both sides.Drug Storage is mixed and made into by Chinese medicine extract and water-soluble glue sample, transdermal enhancer, far-infrared powder, and the weight portion proportioning is: Cinnabaris 1～5 weight portion, Galla Chinensis 1～15 weight portion; Far-infrared powder 0.05～5, penetrating agent 0.1～10.The weight ratio of Drug Storage Chinese medicine and glue is 1: 1～10.
2. according to the double-face external patch of the described treatment night sweat of claim 1, it is characterized in that: used water-soluble glue can adopt the two kinds or more of raw materials of following weight percentage ratio to make among the present invention: chitosan 1～15, gelatin 1～15, polyvinylpyrrolidone (PVP) 1～30, polyvinyl alcohol (PVA) 1～25, polyacrylic acid 1～20, Polyethylene Glycol (PEG) 1～20, sodium carboxymethyl cellulose 1～10, arabic gum 1～20, agar 1～20, sodium alginate 1～15, CBP 1～15, glycerol 1～40, propylene glycol 1～40.
3. according to the double-face external patch of the described treatment night sweat of claim 1, it is characterized in that: the PUR among the present invention can be polyurethanes, esters of acrylic acid, isobutylene type, silicone rubber kinds etc.
4. according to the double-face external patch of the described treatment night sweat of claim 1, it is characterized in that: described penetrating agent comprises dimethyl sulfoxide and analog: dimethyl sulfoxide (DMSO); Azone compounds: laurocapram Azone.
5. according to the double-face external patch of the described treatment night sweat of claim 1, it is characterized in that: used base material can be dried/wet nonwoven fabrics, artificial skin, aluminizer, medical elastic cloth, the spinning cloth of medical cotton textiles.
6. according to the double-face external patch of the described treatment night sweat of claim 1, it is characterized in that: used protecting film can be paper, polyester film, polyethylene film, polypropylene screen, polychloroethylene film, the polystyrene film through release treatment.
7. according to the double-face external patch of the described treatment night sweat of claim 1, it is characterized in that: described preparation process comprises:
1) preparation of Drug Storage: two or more raw materials of above-mentioned water-soluble glue are added in the agitator tank, add a certain amount of water, heat to 50 ℃, after treating that the glue sample stirs, be cooled to 40 ℃ and add drug extract, the penetrating agent that extracts in advance, add far-infrared powder again, add water until the viscosity that is fit to coating.
2) preparation technology:
Base material → coating hot-fusible pressure-sensitive adhesive → multiple protecting film → base material reverse side is coated with Drug Storage → cold drying patent medicine film → multiple Drug Storage protecting film → patch stamping-out → packing of product
8. according to the double-face external patch of the described treatment night sweat of claim 1, it is characterized in that: preparation technology is spreading formation process, extrusion modling or spray mo(u)lding technology.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100534910A CN101601692A (en) | 2008-06-12 | 2008-06-12 | The double-face external patch of treatment night sweat |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100534910A CN101601692A (en) | 2008-06-12 | 2008-06-12 | The double-face external patch of treatment night sweat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101601692A true CN101601692A (en) | 2009-12-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008100534910A Pending CN101601692A (en) | 2008-06-12 | 2008-06-12 | The double-face external patch of treatment night sweat |
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| CN (1) | CN101601692A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526329A (en) * | 2012-02-21 | 2012-07-04 | 简福川 | Traditional Chinese medicine for treating night sweat symptom |
| CN102755547A (en) * | 2012-06-28 | 2012-10-31 | 固镇县中医院 | Acupoint plaster for treating spontaneous perspiration and night sweat |
| CN107496386A (en) * | 2017-07-28 | 2017-12-22 | 安徽众康药业有限公司 | Far infrared arthralgia relief patch and preparation method thereof |
| TWI731667B (en) * | 2020-04-30 | 2021-06-21 | 張振榮 | Preparing method and use of pgc film in dermatitis healing |
-
2008
- 2008-06-12 CN CNA2008100534910A patent/CN101601692A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526329A (en) * | 2012-02-21 | 2012-07-04 | 简福川 | Traditional Chinese medicine for treating night sweat symptom |
| CN102755547A (en) * | 2012-06-28 | 2012-10-31 | 固镇县中医院 | Acupoint plaster for treating spontaneous perspiration and night sweat |
| CN107496386A (en) * | 2017-07-28 | 2017-12-22 | 安徽众康药业有限公司 | Far infrared arthralgia relief patch and preparation method thereof |
| TWI731667B (en) * | 2020-04-30 | 2021-06-21 | 張振榮 | Preparing method and use of pgc film in dermatitis healing |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20091216 |