CN101513259B - Calcium supplementing product - Google Patents
Calcium supplementing product Download PDFInfo
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- CN101513259B CN101513259B CN200910103537XA CN200910103537A CN101513259B CN 101513259 B CN101513259 B CN 101513259B CN 200910103537X A CN200910103537X A CN 200910103537XA CN 200910103537 A CN200910103537 A CN 200910103537A CN 101513259 B CN101513259 B CN 101513259B
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- calcium
- amino acid
- acid chelate
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Abstract
The present invention provides a calcium supplementing product which is characterized in that the calcium supplementing product is composed of the following components according to weight percentage: 2%-5% of Ganoderma Lucidum Polysaccharide, 82%-90% of calcium amino acid chelate, 1%-3% of iron amino acid chelate, 2%-4% of zinc amino acid chelate, 0.5%-1.5% of manganese amino acid chelate, 3%-5% of magnesium amino acid chelate and 0.05%-0.2% of copper amino acid chelate. The calcium supplementing product of the invention can effectively complement the calcium of human body, increases the bone mineral density of human body and has quick and evident calcium complementing effect. The calcium supplementing product settles the problems of inferior solubility of traditional calcium source, low absorption rate, large side effects of lithiasis generation, etc.
Description
Technical field:
The present invention relates to a kind of product of replenishing the calcium.
Technical background:
Calcium is one of most important element of human body, participates in all vital movement processes.At first, calcium is the important component of bone and toothing, has 99% calcium to be deposited on bone approximately.Calcium ion is also participated in many physiological functions, like activity of nerve excitability, contraction of muscle, cardiomotility, permeability of cell membrane, blood clotting process, some enzyme etc.The insufficiency of intake of calcium in meals, simultaneously again less than other when additional, will calcium deficiency in the body.Calcium deficiency can cause insomnia, numb in every limb, tooth mobility, symptom such as aging.Children's calcium deficiency can cause rickets, pregnant woman's calcium deficiency can cause have a pain in the back, symptom such as Leg Cramps, weight person can cause pregnancy-induced hypertension syndrome.The malacosteon and the osteoporosis of fracture can take place to be prone in adult's calcium deficiency.There is the expert to conclude that " calcium is Source of life, and calcium is healthy basis, and calcium is the base of longevity " is justified.
China resident is owing to aspects such as diet structures, and the calcium deficiency phenomenon is very serious.The Chinese government successively organizes and has carried out the investigation of four resident of urban and urual areas of whole country diet nutritionals, and investigation result shows that the intake of calcium is significantly on the low side, the every day that is lower than generally that Chinese Soclety of Nutrition recommends nutrient allowance (RDA) standard in the meals.
In the face of various calcium products, how selecting for use safely and effectively, calcium preparation is another problem that receives publicity.In the recent period; The expert of Chinese Medical Association's osteoporosis and the bone mineral content disease branch suggestion of knowing together is pointed out: in view of calcium and the important function of vitamin D in bone health; And China resident's dietary calcium is taken in general not enough; Therefore, except that meals, selecting with additional calcium according to the principle of science is with the cardinal task that becomes relevant China people ' s health.
Calcium agent kind in the market is more, is clinician and the patient chance that provides more choices.But because the calcium product of selling on the market is scarcely water-soluble or human body is difficult for absorbing, the probability that causes the crowd of replenishing the calcium to suffer from calculus increases greatly, and the patient of bad reactions such as gall stone, kidney stone, urethral calculus take place is clinically increased year by year.
Summary of the invention
The object of the invention just be to provide a kind of water-soluble entirely, the human absorptivity is high, biologically active is high, and can avoid the crowd of replenishing the calcium to suffer from the product of replenishing the calcium of bad reactions such as calculus effectively.
The objective of the invention is to realize like this: a kind of product of replenishing the calcium is characterized in that it is composed of the following components by weight percentage: GL-B 2%～5%, amino acid chelated calcium 82%～90%, amino acid chelated iron 1%～3%, zinc-amino acid chelate 2%～4%, chelating amino acids manganese 0.5%～1.5%, amino acid chelated magnesium 3%～5% and copper amino acid chelate 0.05%～0.2%.
Each component in the above-mentioned product of replenishing the calcium is preferably: GL-B 2%～3%, amino acid chelated calcium 85%～90%, amino acid chelated iron 1%～2%, zinc-amino acid chelate 2%～3%, chelating amino acids manganese 0.5%～1%, amino acid chelated magnesium 3%～4% and copper amino acid chelate 0.1%～0.2%, all by weight percentage.
Each component in the above-mentioned product of replenishing the calcium further is preferably: GL-B 3%, amino acid chelated calcium 88%, amino acid chelated iron 1.5%, zinc-amino acid chelate 3%, chelating amino acids manganese 0.9%, amino acid chelated magnesium 3.5% and copper amino acid chelate 0.1%, all by weight percentage.
Each component in the above-mentioned product of replenishing the calcium is the commercial goods.
The preparation method of the above-mentioned product of replenishing the calcium is: above-mentioned each component is mixed by said ratio get final product.
Beneficial effect of the present invention is:
1, the inventor selects for use amino acid chelated calcium as the calcium source in the product of the present invention; Elements such as iron, zinc, manganese, magnesium and copper have been added simultaneously with the form of amino-acid chelate; Being equipped with Ganodenna Lucidum P.E again is GL-B; Make its product of the present invention that obtains not only water-soluble entirely, and the human absorptivity is high, biologically active is high; Because can element absorption such as calcium and other iron, zinc, manganese, magnesium and copper be gone into blood through the amino acid passage of small intestinal mucosa, can directly be absorbed, and need not to add V by the enteron aisle mocromembrane as amino-acid chelate
D, improved the absorption rate of product of the present invention, be characterized in replenishing effectively the calcium of human body, improve the human body bone density, solved that traditional calcium source is poorly soluble, absorptivity is low and produced the big problem of side effect such as calculus.
2, the inventor is the basis with human body to various mineral element aequums; Fully take into account antagonism between various elements, human body to the assimilation effect of various elements etc., the product of the present invention that obtains through zoopery (seeing table 1, table 2) optimization at last is that a kind of several kinds of mineral elements such as iron, zinc, manganese, magnesium and copper of needed by human body are with the proportioning of mending; Owing to added GL-B, make product of the present invention break through the tradition of replenishing the calcium merely, become a kind of natural nutrient food of replenishing, absorbing comprehensively coordinated.
Table 1 calcium in rats absorptivity, retention rate be (%, X ± S) relatively
Annotate: list same. the identical person of all subscript letters. the expression difference does not have the conspicuousness meaning. the different persons of all subscript letters, expression there was a significant difference meaning (variance analysis P＜0.01).
In the table 1: absorptivity is that the total amount of replenishing the calcium deducts the calcium amount that excretes of stool; The retention rate was retained the ratio that dose accounts for former dose in the body in every separated t hour at the pharmacokinetics middle finger; Certain commercially available prod is calcium carbonate class calcium-enriching products.
Can find out that from table 1 absorptivity of product of the present invention and retention rate all are higher than certain commercially available prod far away, this just proves absolutely that product of the present invention more can effectively be absorbed by body.
Table 2 rat femur calcium, BMC (BMC), bone density (BMD) is (x ± s) relatively
To annotate: list same, the identical person of arbitrary letter is arranged in all subscripts. the expression difference does not have the conspicuousness meaning. the different persons of all subscript letters, expression there was a significant difference meaning.
In the table 2: the A group is reinforcement group, the normal diet of feeding+product of the present invention;
The B group is experimental group, the normal diet of feeding+certain commercially available calcium carbonate class calcium-enriching products;
C is a control group, the normal diet of feeding.
Find out from table 2; Two groups of A, B compare with control group C respectively that all there were significant differences on each index; This expression A, two groups of products of replenishing the calcium of B all are effective; But the A group is compared with the B group and can be found out, its femur calcium of A group, BMC (BMC), the bone density (BMD) of taking product of the present invention all significantly are higher than the B group of taking calcium carbonate, and this just further shows that the absorb effect of product of the present invention in body is to be higher than calcium carbonate class calcium-enriching products far away.
3, product effect of supplemented calcium of the present invention is obvious fast, and every 1000mg is equivalent to the amount of replenishing the calcium of 5 liters of milk, has no toxic and side effect.
The specific embodiment
Further specify the present invention through embodiment below, but the present invention is not limited to these embodiment.
Embodiment 1: a kind of product of replenishing the calcium, and wherein each set of dispense ratio is seen table 3, each component is the commercial goods; Its preparation method is: said each component is mixed by said proportioning get final product.
Embodiment 2～embodiment 6: wherein each set of dispense ratio is seen table 3, and its preparation method is with embodiment 1.
The set of dispense of table 3 product embodiments 1～embodiment 6 of the present invention is than (by weight percentage)
| Component | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 |
| GL-B | 3 | 2 | 2.5 | 3.5 | 4 | 5 |
| Amino acid chelated calcium | 88 | 82 | 85 | 87 | 88.5 | 90 |
| Amino acid chelated iron | 1.5 | 1 | 1.8 | 2 | 2.5 | 3 |
| Zinc-amino acid chelate | 3 | 2 | 2.4 | 2.9 | 3.5 | 4 |
| Chelating amino acids manganese | 0.9 | 0.5 | 1 | 1.2 | 1.4 | 1.5 |
| Amino acid chelated magnesium | 3.5 | 3 | 3.8 | 4 | 4.6 | 5 |
| Copper amino acid chelate | 0.1 | 0.05 | 0.08 | 0.13 | 0.17 | 0.2 |
Claims (5)
1. the product of replenishing the calcium is characterized in that it is composed of the following components by weight percentage: GL-B 2%～5%, amino acid chelated calcium 82%～90%, amino acid chelated iron 1%～3%, zinc-amino acid chelate 2%～4%, chelating amino acids manganese 0.5%～1.5%, amino acid chelated magnesium 3%～5% and copper amino acid chelate 0.05%～0.2%.
2. the product of replenishing the calcium as claimed in claim 1; Wherein: GL-B 2%～3%, amino acid chelated calcium 85%～90%, amino acid chelated iron 1%～2%, zinc-amino acid chelate 2%～3%, chelating amino acids manganese 0.5%～1%, amino acid chelated magnesium 3%～4% and copper amino acid chelate 0.1%～0.2%, all by weight percentage.
3. the product of replenishing the calcium as claimed in claim 2; Wherein: GL-B 3%, amino acid chelated calcium 88%, amino acid chelated iron 1.5%, zinc-amino acid chelate 3%, chelating amino acids manganese 0.9%, amino acid chelated magnesium 3.5% and copper amino acid chelate 0.1%, all by weight percentage.
4. like claim 1, the 2 or 3 described products of replenishing the calcium, wherein said each component is the commercial goods.
5. like the preparation method of the described product of replenishing the calcium of arbitrary claim in the claim 1～4, it is characterized in that it is said each component to be mixed by said proportioning get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910103537XA CN101513259B (en) | 2009-04-03 | 2009-04-03 | Calcium supplementing product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200910103537XA CN101513259B (en) | 2009-04-03 | 2009-04-03 | Calcium supplementing product |
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| Publication Number | Publication Date |
|---|---|
| CN101513259A CN101513259A (en) | 2009-08-26 |
| CN101513259B true CN101513259B (en) | 2012-01-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200910103537XA Active CN101513259B (en) | 2009-04-03 | 2009-04-03 | Calcium supplementing product |
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| Country | Link |
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| CN (1) | CN101513259B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3752168A4 (en) * | 2018-02-14 | 2021-10-13 | Profeat Biotechnology Co. Ltd. | Use of ferrous amino acid chelate to increase calcium absorption and bone mass, and to treat osteoporosis |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103238827A (en) * | 2012-02-10 | 2013-08-14 | 王慎君 | Composite nutrient preparation formula |
Citations (4)
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|---|---|---|---|---|
| CN1460422A (en) * | 2003-06-15 | 2003-12-10 | 刘蒙榕 | Composite enriched nutrient cream candy and its production method |
| CN1460518A (en) * | 2003-06-15 | 2003-12-10 | 刘蒙榕 | Composite enriched nutrient tablet |
| CN1757409A (en) * | 2005-09-20 | 2006-04-12 | 上海泰运科技有限公司 | Recipe of Wanshou capsule, and health-care function |
| CN1762236A (en) * | 2005-11-02 | 2006-04-26 | 江中药业股份有限公司 | Health-caring product capable of increasing human immunity and its preparation method |
-
2009
- 2009-04-03 CN CN200910103537XA patent/CN101513259B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1460422A (en) * | 2003-06-15 | 2003-12-10 | 刘蒙榕 | Composite enriched nutrient cream candy and its production method |
| CN1460518A (en) * | 2003-06-15 | 2003-12-10 | 刘蒙榕 | Composite enriched nutrient tablet |
| CN1757409A (en) * | 2005-09-20 | 2006-04-12 | 上海泰运科技有限公司 | Recipe of Wanshou capsule, and health-care function |
| CN1762236A (en) * | 2005-11-02 | 2006-04-26 | 江中药业股份有限公司 | Health-caring product capable of increasing human immunity and its preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 朱旭红.《氨基酸鳌合钙用于孕妇血铅过高》.《中国临床保健杂志》.2008,第11卷(第3期),306-307. * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3752168A4 (en) * | 2018-02-14 | 2021-10-13 | Profeat Biotechnology Co. Ltd. | Use of ferrous amino acid chelate to increase calcium absorption and bone mass, and to treat osteoporosis |
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| Publication number | Publication date |
|---|---|
| CN101513259A (en) | 2009-08-26 |
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