CN101501036A - 取代的吡唑并嘧啶,其制备方法及其作为药物的用途 - Google Patents

取代的吡唑并嘧啶,其制备方法及其作为药物的用途 Download PDF

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Publication number
CN101501036A
CN101501036A CN200780029092.4A CN200780029092A CN101501036A CN 101501036 A CN101501036 A CN 101501036A CN 200780029092 A CN200780029092 A CN 200780029092A CN 101501036 A CN101501036 A CN 101501036A
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CN
China
Prior art keywords
pyrazolo
pyrimidin
dihydro
methanone
isoquinolin
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CN200780029092.4A
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English (en)
Chinese (zh)
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CN101501036B (zh
Inventor
沃伊切赫·达内什
安杰伊·德孔迪
米尔科·黑兴贝格尔
马库斯·亨里希
克劳迪娅·亚茨克
延斯·纳格尔
克里斯托弗·格雷厄姆·拉斐尔·帕森斯
塔尼娅·魏尔
西比勒·米勒
尤里斯·丰蒂斯
亚历山德拉·古特凯特斯
罗纳尔兹·泽姆里博
瓦莱里扬斯·考斯
拉里莎·考林纳
埃利娜·厄尔德曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merz Pharma GmbH and Co KGaA
Original Assignee
Merz Pharma GmbH and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by Merz Pharma GmbH and Co KGaA filed Critical Merz Pharma GmbH and Co KGaA
Priority claimed from PCT/EP2007/058060 external-priority patent/WO2008015269A1/en
Publication of CN101501036A publication Critical patent/CN101501036A/zh
Application granted granted Critical
Publication of CN101501036B publication Critical patent/CN101501036B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200780029092.4A 2006-08-04 2007-08-03 取代的吡唑并嘧啶,其制备方法及其作为药物的用途 Expired - Fee Related CN101501036B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US83582006P 2006-08-04 2006-08-04
US60/835,820 2006-08-04
US87754406P 2006-12-28 2006-12-28
US60/877,544 2006-12-28
PCT/EP2007/058060 WO2008015269A1 (en) 2006-08-04 2007-08-03 Substituted pyrazolopyrimidines, a process for their preparation and their use as medicine

Publications (2)

Publication Number Publication Date
CN101501036A true CN101501036A (zh) 2009-08-05
CN101501036B CN101501036B (zh) 2013-04-17

Family

ID=40947308

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA2007800290958A Pending CN101501042A (zh) 2006-08-04 2007-08-03 吡唑并嘧啶,其制备方法以及其作为药物的用途
CN200780029092.4A Expired - Fee Related CN101501036B (zh) 2006-08-04 2007-08-03 取代的吡唑并嘧啶,其制备方法及其作为药物的用途

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CNA2007800290958A Pending CN101501042A (zh) 2006-08-04 2007-08-03 吡唑并嘧啶,其制备方法以及其作为药物的用途

Country Status (3)

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CN (2) CN101501042A (ar)
ES (2) ES2356576T3 (ar)
SI (1) SI2054416T1 (ar)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102695709A (zh) * 2009-11-25 2012-09-26 德国麦氏大药厂 取代吡唑并嘧啶的晶型
CN110872297A (zh) * 2018-09-04 2020-03-10 上海再极医药科技有限公司 氨基嘧啶并五元杂环化合物、其中间体、制备方法、药物组合物及应用
CN118141811A (zh) * 2024-03-06 2024-06-07 中山大学中山眼科中心 Yap/taz抑制剂-2在制备预防和/或治疗由病原微生物感染引起的角膜疾病药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988339A (en) * 1974-02-08 1976-10-26 Smithkline Corporation Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase
EP1506196B1 (en) * 2001-11-01 2012-01-18 Icagen, Inc. Pyrazolopyrimidines as sodium channel inhibitors

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102695709A (zh) * 2009-11-25 2012-09-26 德国麦氏大药厂 取代吡唑并嘧啶的晶型
CN110872297A (zh) * 2018-09-04 2020-03-10 上海再极医药科技有限公司 氨基嘧啶并五元杂环化合物、其中间体、制备方法、药物组合物及应用
CN118141811A (zh) * 2024-03-06 2024-06-07 中山大学中山眼科中心 Yap/taz抑制剂-2在制备预防和/或治疗由病原微生物感染引起的角膜疾病药物中的应用
CN118141811B (zh) * 2024-03-06 2024-11-29 中山大学中山眼科中心 Yap/taz抑制剂-2在制备预防和/或治疗由病原微生物感染引起的角膜疾病药物中的应用

Also Published As

Publication number Publication date
CN101501042A (zh) 2009-08-05
ES2359447T3 (es) 2011-05-23
SI2054416T1 (sl) 2011-05-31
CN101501036B (zh) 2013-04-17
ES2356576T3 (es) 2011-04-11

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