CN101501036A - 取代的吡唑并嘧啶,其制备方法及其作为药物的用途 - Google Patents
取代的吡唑并嘧啶,其制备方法及其作为药物的用途 Download PDFInfo
- Publication number
- CN101501036A CN101501036A CN200780029092.4A CN200780029092A CN101501036A CN 101501036 A CN101501036 A CN 101501036A CN 200780029092 A CN200780029092 A CN 200780029092A CN 101501036 A CN101501036 A CN 101501036A
- Authority
- CN
- China
- Prior art keywords
- pyrazolo
- pyrimidin
- dihydro
- methanone
- isoquinolin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 239000001257 hydrogen Substances 0.000 abstract description 86
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PCT/EP2007/058060 WO2008015269A1 (en) | 2006-08-04 | 2007-08-03 | Substituted pyrazolopyrimidines, a process for their preparation and their use as medicine |
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CN101501036A true CN101501036A (zh) | 2009-08-05 |
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CN200780029092.4A Expired - Fee Related CN101501036B (zh) | 2006-08-04 | 2007-08-03 | 取代的吡唑并嘧啶,其制备方法及其作为药物的用途 |
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ES (2) | ES2356576T3 (ar) |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102695709A (zh) * | 2009-11-25 | 2012-09-26 | 德国麦氏大药厂 | 取代吡唑并嘧啶的晶型 |
CN110872297A (zh) * | 2018-09-04 | 2020-03-10 | 上海再极医药科技有限公司 | 氨基嘧啶并五元杂环化合物、其中间体、制备方法、药物组合物及应用 |
CN118141811A (zh) * | 2024-03-06 | 2024-06-07 | 中山大学中山眼科中心 | Yap/taz抑制剂-2在制备预防和/或治疗由病原微生物感染引起的角膜疾病药物中的应用 |
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US3988339A (en) * | 1974-02-08 | 1976-10-26 | Smithkline Corporation | Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase |
EP1506196B1 (en) * | 2001-11-01 | 2012-01-18 | Icagen, Inc. | Pyrazolopyrimidines as sodium channel inhibitors |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102695709A (zh) * | 2009-11-25 | 2012-09-26 | 德国麦氏大药厂 | 取代吡唑并嘧啶的晶型 |
CN110872297A (zh) * | 2018-09-04 | 2020-03-10 | 上海再极医药科技有限公司 | 氨基嘧啶并五元杂环化合物、其中间体、制备方法、药物组合物及应用 |
CN118141811A (zh) * | 2024-03-06 | 2024-06-07 | 中山大学中山眼科中心 | Yap/taz抑制剂-2在制备预防和/或治疗由病原微生物感染引起的角膜疾病药物中的应用 |
CN118141811B (zh) * | 2024-03-06 | 2024-11-29 | 中山大学中山眼科中心 | Yap/taz抑制剂-2在制备预防和/或治疗由病原微生物感染引起的角膜疾病药物中的应用 |
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Publication number | Publication date |
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CN101501042A (zh) | 2009-08-05 |
ES2359447T3 (es) | 2011-05-23 |
SI2054416T1 (sl) | 2011-05-31 |
CN101501036B (zh) | 2013-04-17 |
ES2356576T3 (es) | 2011-04-11 |
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