CN101485456B - Throat-clearing and oxidation-resisting health-care functional foodstuffs - Google Patents
Throat-clearing and oxidation-resisting health-care functional foodstuffs Download PDFInfo
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Abstract
The invention relates to health-care functional food for clearing throat and resisting oxidation, in particular to health-care food prepared from dendrobium nobile and a medicine of phyllanthus emblica commonly used by Tibetan ethnic minority and yi ethnic minority which are taken as raw materials. The health-care functional food is prepared by evenly mixing dendrobium nobile powder with granularity of not less than 60 meshes and phyllanthus emblica extract; and two materials are mixed in portion by weight: 6 to 10 portions of the dendrobium nobile and 1 to 4 portions of the phyllanthus emblica extract. The functional food reasonably and organically combines goods with homology of drug and food to prepare the health-care food with remarkable effect, has the efficacies of clearing and moistening throat, resisting oxidation and tonifying deficiency and loss of viscera, can obviously improve a series of pharyngeal symptoms of pharyngeal discomfort people, and has the functions of resisting oxidation and delaying senility.
Description
Technical field
The present invention relates to a kind of clearing and oxidation-resisting health-care functional foodstuffs, particularly adopting HERBA DENDROBII and Tibetan, Yi nationality, distributed over Yunnan, Sichuan and Guizhou's conventional crude drugs emblic is the health food of raw material preparation.
Background technology
Day by day abominable along with people's living environment, tobacco and wine are excessively, dust and pernicious gas stimulate and often cause upper respiratory tract inflammation, and increasing people suffers from throat class disease and delay is difficult.The traditional Chinese medical science is called sphagitis " larynx numbness ", and existing external cause occurs for it, and internal cause is also arranged.Internal cause is lung stomach intrinsic heat usually, and external cause is to feel in ailment said due to cold or exposure, pestilential pathogen.Show as dysphonia, even hoarse, garget, pain, drying, do not have burning heat sensation and pharynx food smooth etc.Often edible throat-clearing throat-moistening functional food can play the health-care effect of relief of symptoms and auxiliary improvement sign.
Any life process is all being followed growth, growth, old and feeble rule.The traditional Chinese medical science is thought, the spleen being the foundation of acquired constitution, source of generating QI and blood, and all materials that sustain life in the human body growth and development process all depend on the transporting of taste.If taste are not enough, insufficiency of generating and transforming QI and blood then, each is dirty all empty, has also just caused body aging.At present, China aged has reached 1.2 hundred million more than.It is predicted, to the year two thousand twenty, elderly population will reach 1.64 hundred million in 65 years old, account for 16.1% of total population proportion.Along with modern humans society progressively steps into aging, the proportion of anti-oxidation health product in healthcare industry will continue to increase, and demand will constantly increase.The food that exploitation has the anti-oxidation health function has important society and economic implications, meets modern's life requirement.
HERBA DENDROBII is the stem of the orchid family Dendrobium Sw HERBA DENDROBII, is the famous and precious rare Chinese medicine of China's tradition, has extensively long applicating history.Begin to be stated from Shennong's Herbal, classify as top gradely, the successive dynasties book on Chinese herbal medicine is all on the books.The Shennong's Herbal record: " ... distinguish the flavor of sweet, flat, nontoxic.In curing the wound, except numbness, lower gas, the tonifying five zang organs consumptive disease, win thin, reinforcing yin essence.Take for a long time thick stomach, make light of one's life by commiting suicide, prolong life, longue meat, by skin heat symptoms caused by an exopathgen ， Rush gas, sedate is except frightened ... ".Supplementary Amplifications of the Compendium of Materia Medica (clear Zhao Xuemin): " clearing stomach is promoted the production of body fluid except abnormal heat, strain, with for tea, Appetizing spleen-tonifying, wind is treated in arresting convulsion, can press down saliva phlegm, relieving summer-heat, sweet fragrant sending down abnormally ascending ".One one of the Pharmacopoeia of the People's Republic of China (version in 2005) carries: [nature and flavor with return through] hardship is slightly cold.Return stomach, kidney channel.[function with cure mainly] reinforcing stomach reg fluid is nourishing Yin and clearing heat.Be used for the moon and hinder body fluid deficiency, the dry polydipsia, food is few retches, abnormal heat after being ill, order is secretly not clear.
Emblic subsystem Tibetan, Yi nationality, distributed over Yunnan, Sichuan and Guizhou's conventional crude drugs.Another name Yunnan olive, Phyllanthus embical fruit, Chinese olive etc.Be the ripening fruits of euphorbia plant emblic, flavor acid is little puckery, attaches to the lung and stomach meridians.Be rich in the effective active compositions such as tannin and phenolic acid compound, flavone compound, alkaloid compound, vitamin, amino acid, trace element.Has clearing heat and cooling blood, food digesting stomach fortifying, the functions such as cough-relieving of promoting the production of body fluid.Be used for the blood-head blood stasis, indigestion, abdominal distension, cough, laryngalgia, dry etc.
At present, the HERBA DENDROBII imitating wild planting is successful industrialization at home, and raw material supply is secure.The emblic wild resource is abundant, and the innovation is conducive to take full advantage of resource, promote the well-being of mankind, and potential preferably economic benefit.
Summary of the invention
Technical problem to be solved by this invention provides a kind of clearing and oxidation-resisting health-care functional foodstuffs, and the HERBA DENDROBII of raw material employing integration of drinking and medicinal herbs and Tibetan, Yi nationality, distributed over Yunnan, Sichuan and Guizhou's conventional crude drugs emblic have clearing and oxidation-resisting health-care effect.
Solving the scheme that technical problem of the present invention adopts is: mixed and formed by granularity 〉=60 purpose HERBA DENDROBII powder, emblic extract, and the ratio of the mixed weight umber of the two is: 6～10 parts of HERBA DENDROBIIs, 1～4 part of emblic extract.Can reach significant health-care efficacy to pharyngeal uncomfortable person and the elderly.
Compatibility foundation of the present invention: HERBA DENDROBII is distinguished the flavor of sweet cool in nature, returns stomach, kidney channel, can be nourishing Yin and clearing heat, and reinforcing stomach reg fluid is monarch drug in a prescription, sweet, sour, the little adstringency of emblic flavor is cool, attaches to the lung and stomach meridians energy principal drug assistance clearing heat and promoting fluid, invigorating spleen and reinforcing stomach.The two mutual reinforcement between is usefulness, and cool profit is gentle, plays altogether clearing heat and promoting fluid, the merit of invigorating spleen and reinforcing stomach.Pharyngeal uncomfortable person and the elderly there is good health-care efficacy.
The invention has the beneficial effects as follows: the functional food that adopts HERBA DENDROBII, emblic to produce, can give full play to the effect of HERBA DENDROBII and emblic, specially for pharyngeal uncomfortable person and middle-aged and old health foods, its obvious health-care efficacy, edible safety is reliable, has no side effect.
Aspect clearing: according to " health food check and assessment technique standard ", the chronic pharyngitis crowd of the tested inclusion criteria of Pass Test takes this health functional food after 15 days continuously, pharyngeal symptom, somatic feature score obviously reduce, and always improvement rate of symptom is 100%, and always improvement rate of sign is 95.0%.As seen this health functional food has function of clearing throat.
Aspect anti-oxidant: according to " health food check and assessment technique standard ", the age of the tested inclusion criteria of Pass Test is taken this health functional food after four months continuously 45～65 years old crowd, Serum Lipid Peroxide reduces, and activity of glutathione peroxidase raises.As seen this health functional food has the anti-oxidation function effect.
The particular utility that this prescription has not only heat-clearing but also nourishes, clearing, antioxidation are remarkable.
The specific embodiment
Embodiment 1: medicine of the present invention is comprised of following component: (weight proportion)
Main component: 8 parts of HERBA DENDROBIIs, 2 parts of emblic extracts.
The preparation method step:
Step 1: HERBA DENDROBII crushed after being dried, mistake 60 mesh sieves, get powder;
Step 2: cross 60 mesh sieves after HERBA DENDROBII powder, emblic extract mix, with the amount capsule charge of 0.18g.
Embodiment 2: medicine of the present invention is comprised of following component: (weight proportion)
Main component: 6 parts of HERBA DENDROBIIs, 4 parts of emblic extracts;
Preparation method step: with embodiment 1.
Embodiment 3: medicine of the present invention is comprised of following component: (weight proportion)
Main component: 7 parts of HERBA DENDROBIIs, 3 parts of emblic extracts;
Preparation method step: with embodiment 1.
Embodiment 4: medicine of the present invention is comprised of following component: (weight proportion)
Main component: 9 parts of HERBA DENDROBIIs, 1 part of emblic extract.
Preparation method step: with embodiment 1.
Above-described embodiment is used for pharyngeal uncomfortable person is had the clearing effect and to the functional food of middle-aged and old Wheat Proteins, through general preparation process, can make multiple formulation, such as capsule, tablet, powder, electuary, paste or granule.
The result of function test of the present invention:
The capsule that adopts above-described embodiment 1 prescription to make carries out function test and evaluation of test result according to the regulation of Ministry of Public Health's " health food check and assessment technique standard (2003 editions) ".
One, the result of the test of function of moistening and cleaning throat
1, ordinary circumstance: meet this chronic pharyngitis crowd who tests tested inclusion criteria 120 examples, be divided at random test group and control group, every group of 60 examples.Before the test-meal, test group and control group crowd's age, mental status, sleep quality, diet situation etc. are basically identical.The front two groups of crowds' of test-meal pharyngeal symptom, somatic feature score all do not have notable difference, see Table 1.
The front two groups of pharyngeal symptoms of crowd of table 1 test-meal, somatic feature score are relatively
2, this health functional food is on the impact of chronic pharyngitis crowd efficiency index
After the test-meal, the pharyngeal symptom integral of test group and somatic feature score be all less than before the test-meal, and self comparing difference has utmost point conspicuousness.The pharyngeal symptom integral of test group and somatic feature score be all less than control group after the test-meal, and two groups difference has utmost point conspicuousness; Improvement rate and the total effective rate of the various pharyngeal sings and symptomses of test group all are higher than control group, and both difference all has utmost point conspicuousness, see Table 2-4, show that this health functional food has the effect of the pharyngeal sings and symptoms that alleviates the examination trencherman.
Two groups of pharyngeal symptom integrals of crowd relatively before and after table 2 test-meal
| Group | Number | Before the test-meal | After the test-meal | P value (self) |
| Control group | 60 | 13.15±1.05 | 12.29±1.65 | P＞0.05 |
| The test-meal group | 60 | 13.65±1.15 | 9.19±1.36 | P＜0.01 |
| P value (between group) | P＞0.05 | P＜0.01 | -- |
Two groups of crowds' pharyngeal somatic feature score relatively before and after table 3 test-meal
| Group | Number | Before the test-meal | After the test-meal | P value (self) |
| Control group | 60 | 8.48±1.16 | 7.92±1.17 | P＞0.05 |
| The test-meal group | 60 | 8.56±1.21 | 5.29±1.20 | P＜0.01 |
| P value (between group) | P＞0.05 | P＜0.01 | -- |
The table 4 pair effective situation of chronic pharyngitis crowd
Data can be found out from above table, and test group is taken this product after 15 days continuously, and pharyngeal symptom, somatic feature score obviously reduce, and always improvement rate of symptom is 100.0%, and always improvement rate of sign is 95.0%.Show that this product has function of moistening and cleaning throat.
Two, the result of the test of anti-oxidation function
1, ordinary circumstance: meet this crowd who tests tested inclusion criteria 120 examples, be divided at random test group and control group, every group of 60 examples.Before the test-meal, test group and control group crowd's age, mental status, sleep quality, diet situation etc. are basically identical.The front two groups of crowds' of test-meal LPO, superoxide dismutase activity and activity of glutathione peroxidase relatively all do not have notable difference, see Table 5.
The front two groups of crowd's basic conditions of table 5 test-meal
2, on the impact of Serum Lipid Peroxide
The front two groups of crowds' of test-meal Serum LPO Levels (MDA) content no significant difference.After the test-meal, test group crowd's Serum Lipid Peroxide is starkly lower than control group, and rate of descent is also obviously greater than control group, and difference all has conspicuousness; Serum Lipid Peroxide after the simultaneously test group test-meal obviously reduces before than test-meal, and difference has very significant, shows that this health functional food has the effect of the Serum Lipid Peroxide that reduces the examination trencherman, sees Table 6.
Two groups of crowds' Serum Lipid Peroxide changes before and after table 6 test-meal
| Group | Number | MDA (nmoL/mL) before the test-meal | MDA after the test-meal (nmoL/mL) | P value (self) | Rate of descent (%) |
| Control group | 60 | 4.67±0.97 | 4.41±1.02 | P＞0.05 | 5.18 |
| The test-meal group | 60 | 4.58±1.08 | 2.76±1.56 | P＜0.01 | 38.05 |
| P value (between group) | -- | P＞0.05 | P＜0.01 | -- | P＜0.01 |
3, on the active impact of serum superoxide dismutases (SOD)
The front two groups of crowds' of test-meal serum superoxide dismutases active matter significant difference.After the test-meal, test group crowd and control group crowd's serum superoxide dismutases activity all slightly has rising, and two groups rate of rise difference is not obvious, and there are no significant for difference, show this functional food do not raise the examination trencherman the serum superoxide dismutases active function, see Table 7.
Two groups of crowds' serum superoxide dismutases changes before and after table 7 test-meal
| Group | Number | SOD (NU/mL) before the test-meal | SOD after the test-meal (NU/mL) | P value (self) | Rate of rise (%) |
| Control group | 60 | 84.68±15.73 | 85.96±13.14 | P＞0.05 | 3.17 |
| The test-meal group | 60 | 83.02±15.98 | 85.64±15.39 | P＞0.05 | 4.02 |
| P value (between group) | -- | P＞0.05 | P＞0.05 | -- | P＞0.05 |
4, on the active impact of serum glutathione peroxidase (GSH-Px)
The serum activity of glutathione peroxidase no significant difference that test-meal is front two groups.After the test-meal, the serum activity of glutathione peroxidase of test group is higher than control group, and rate of rise is also greater than control group, and difference all has conspicuousness; Serum activity of glutathione peroxidase after the simultaneously test group test-meal raises before than test-meal, and difference has conspicuousness, shows that this functional food has the effect of the examination trencherman serum activity of glutathione peroxidase that raises, and sees Table 8.
Two groups of crowds' serum activity of glutathione peroxidase changes before and after table 8 test-meal
| Group | Number | GSH-Px (NU/mL) before the test-meal | GSH-Px after the test-meal (NU/mL) | P value (self) | Rate of rise (%) |
| Control group | 60 | 110.11±18.57 | 104.53±16.25 | P＞0.05 | -4.06 |
| The test-meal group | 60 | 109.83±19.06 | 105.08±18.61 | P＜0.05 | 9.24 |
| P value (between group) | -- | P＞0.05 | P＜0.05 | -- | P＜0.05 |
Data can be found out from above table, and test group is taken this product after 4 months continuously, and Serum Lipid Peroxide reduces, and activity of glutathione peroxidase raises.Show that this product has the anti-oxidation function effect.
Claims (1)
1. a clearing, oxidation-resisting health-care functional foodstuffs, it is characterized in that: mixed by granularity 〉=60 purpose HERBA DENDROBII powder and emblic extract and form, the ratio of the mixed weight umber of HERBA DENDROBII powder, emblic extract is 6～10 parts of HERBA DENDROBIIs, 1～4 part of emblic extract.
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| CN107232593A (en) * | 2017-06-22 | 2017-10-10 | 云南中医学院 | Composition of the olive containing Yunnan and its production and use |
| CN107296230A (en) * | 2017-06-22 | 2017-10-27 | 云南中医学院 | Lozenge of the olive containing Yunnan and preparation method thereof |
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Non-Patent Citations (2)
| Title |
|---|
| 余楚钦，申楼，张宇喆.《余甘子的药理研究及应用》.《中国实用医药》.2007,第2卷(第36期),169－171. * |
| 郑晓珂,曹新伟,冯卫生,等.《金钗石斛的研究进展》.《中国新药杂志》.2005,第14卷(第7期),826-829. * |
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