CN101484161A - 大麻素受体拮抗剂/反向激动剂 - Google Patents
大麻素受体拮抗剂/反向激动剂 Download PDFInfo
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- CN101484161A CN101484161A CNA2007800249328A CN200780024932A CN101484161A CN 101484161 A CN101484161 A CN 101484161A CN A2007800249328 A CNA2007800249328 A CN A2007800249328A CN 200780024932 A CN200780024932 A CN 200780024932A CN 101484161 A CN101484161 A CN 101484161A
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Landscapes
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| AU (1) | AU2007247878B2 (enExample) |
| CA (1) | CA2651385C (enExample) |
| ES (1) | ES2389569T3 (enExample) |
| IL (1) | IL195071A (enExample) |
| WO (1) | WO2007131219A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103547263A (zh) * | 2010-11-18 | 2014-01-29 | 詹里恩探索公司 | 对于治疗代谢性疾病，包括肥胖症和糖尿病有用的大麻素受体拮抗剂/反相激动剂 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US7655685B2 (en) * | 2007-11-02 | 2010-02-02 | Jenrin Discovery, Inc. | Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes |
| WO2009085198A2 (en) * | 2007-12-20 | 2009-07-09 | Indigene Pharmaceuticals, Inc. | Combination of metformin r-(+)-lipoate and antiobesity agents for the treatment of diabetic hyperglycemia and diabetic complications |
| EP2242745A1 (de) * | 2008-02-07 | 2010-10-27 | Sanofi-Aventis | Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2011044370A1 (en) | 2009-10-07 | 2011-04-14 | Jenrin Discovery | Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes |
| EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8680131B2 (en) | 2012-07-25 | 2014-03-25 | Jenrin Discovery, Inc. | Cannabinoid receptor antagonists/inverse agonists useful for treating disease conditions, including metabolic disorders and cancers |
| US9765031B2 (en) | 2012-11-13 | 2017-09-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cannabinoid receptor mediating compounds |
| US11155521B2 (en) | 2012-11-13 | 2021-10-26 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Cannabinoid receptor mediating compounds |
| AU2015255765A1 (en) * | 2014-05-09 | 2016-11-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Pyrazole derivatives and their use as cannabinoid receptor mediators |
| KR20210152312A (ko) | 2020-06-08 | 2021-12-15 | 주식회사 종근당 | 카나비노이드 수용체 (cb1 수용체) 길항제로서의 4-(4,5-디하이드로-1h-피라졸-1-닐)피리미딘 화합물 및 이를 포함하는 약제학적 조성물 |
| WO2023089612A1 (en) | 2021-11-19 | 2023-05-25 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Peripheral cb1 receptor antagonists for treatment of lower urinary tract symptoms (luts) |
Family Cites Families (8)
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| EP0882029B1 (en) | 1996-02-02 | 2003-04-02 | Merck & Co., Inc. | Heterocyclic derivatives as antidiabetic and antiobesity agents |
| CA2244831A1 (en) | 1996-02-02 | 1997-08-07 | John T. Olson | Method of treating diabetes and related disease states |
| WO1997028115A1 (en) | 1996-02-02 | 1997-08-07 | Merck & Co., Inc. | Antidiabetic agents |
| EP0904079B1 (en) | 1996-02-02 | 2004-03-24 | Merck & Co., Inc. | Antidiabetic agents |
| HUP0204519A3 (en) * | 2000-03-23 | 2003-07-28 | Solvay Pharm Bv | 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity, pharmaceutical compositions containing them and process for their preparations |
| HUP0402113A3 (en) * | 2001-09-21 | 2012-05-29 | Solvay Pharm Bv | 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity, preparation and use thereof |
| KR100903760B1 (ko) * | 2001-09-21 | 2009-06-19 | 솔베이 파마슈티칼스 비. 브이 | Ｃｂ1-길항 작용을 가지는 신규한4,5-디하이드로-1ｈ-피라졸 유도체 |
| US7655685B2 (en) * | 2007-11-02 | 2010-02-02 | Jenrin Discovery, Inc. | Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes |
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- 2007-05-07 WO PCT/US2007/068342 patent/WO2007131219A2/en not_active Ceased
- 2007-05-07 AU AU2007247878A patent/AU2007247878B2/en not_active Ceased
- 2007-05-07 CN CNA2007800249328A patent/CN101484161A/zh active Pending
- 2007-05-07 EP EP07761946A patent/EP2023920B1/en not_active Not-in-force
- 2007-05-07 JP JP2009510118A patent/JP5561720B2/ja not_active Expired - Fee Related
- 2007-05-07 CA CA2651385A patent/CA2651385C/en active Active
- 2007-05-07 US US11/745,162 patent/US7482470B2/en active Active
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2008
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2010
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2011
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103547263A (zh) * | 2010-11-18 | 2014-01-29 | 詹里恩探索公司 | 对于治疗代谢性疾病，包括肥胖症和糖尿病有用的大麻素受体拮抗剂/反相激动剂 |
| CN103547263B (zh) * | 2010-11-18 | 2015-12-09 | 詹里恩探索公司 | 对于治疗代谢性疾病，包括肥胖症和糖尿病有用的大麻素受体拮抗剂/反相激动剂 |
Also Published As
| Publication number | Publication date |
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| JP5561720B2 (ja) | 2014-07-30 |
| US20070259934A1 (en) | 2007-11-08 |
| AU2007247878A1 (en) | 2007-11-15 |
| US20130005784A1 (en) | 2013-01-03 |
| US20100152260A1 (en) | 2010-06-17 |
| EP2023920A2 (en) | 2009-02-18 |
| EP2023920A4 (en) | 2010-06-02 |
| US7666889B2 (en) | 2010-02-23 |
| IL195071A0 (en) | 2009-08-03 |
| US20090036511A1 (en) | 2009-02-05 |
| US7482470B2 (en) | 2009-01-27 |
| EP2023920B1 (en) | 2012-06-13 |
| CA2651385A1 (en) | 2007-11-15 |
| IL195071A (en) | 2014-07-31 |
| ES2389569T3 (es) | 2012-10-29 |
| JP2009536221A (ja) | 2009-10-08 |
| WO2007131219A3 (en) | 2008-11-13 |
| WO2007131219A2 (en) | 2007-11-15 |
| CA2651385C (en) | 2015-02-03 |
| AU2007247878B2 (en) | 2012-05-31 |
| US8088809B2 (en) | 2012-01-03 |
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