CN101482519B - Detection apparatus for phase foreign body in fluid - Google Patents

Detection apparatus for phase foreign body in fluid Download PDF

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Publication number
CN101482519B
CN101482519B CN 200910096073 CN200910096073A CN101482519B CN 101482519 B CN101482519 B CN 101482519B CN 200910096073 CN200910096073 CN 200910096073 CN 200910096073 A CN200910096073 A CN 200910096073A CN 101482519 B CN101482519 B CN 101482519B
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signal
phase
fluid
phase contrast
demodulator
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CN101482519A (en
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蒋惠忠
沈海滨
高秀敏
李劲松
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Zhejiang Lover Health Science and Technology Development Co Ltd
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蒋惠忠
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Abstract

The invention relates to a phase foreign-matter detection device in liquid. The existing technique is easily subjected to the external interference, has low signal-noise ratio and sensitivity and complicated system constitutes. Using a phase contrast technique and light-signal modulation technique, the emergent light-beam of a light-source module is modulated by a signal generator and then processed by a light-beam shaping device, fluid to be tested, a phase contrast imaging object-lens module and a photo detector array; the modulated light-beam permeation signal acquired by the photo detector array is demodulates by a signal demodulator and the information of the presence of the phase foreign-matter is detected. The phase foreign-matter detection device has features of high sensitivity and signal-to-noise ratio, high stability, strong anti-interference capability, simple and reasonable structure, low mechanical location requirement.

Description

A kind of detection apparatus for phase foreign body in fluid
Technical field
The invention belongs to optical technical field, relate to a kind of detection device for foreign matter, particularly a kind of detection apparatus for phase foreign body in fluid.Be mainly used in the foreign matter detection of the fluid products such as medicine, transfusion, oral liquid, beverage in medicine and beverage industry.
Technical background
Detection device for foreign matter refers in the productions such as medicine, beverage and quality inspection process, the device that the fluid products such as transparent or semitransparent medicine, infusion bottle, oral liquid are carried out quality testing.Foreign matter in bottled fluid product detects in main test fluid whether contain the various materials that are insoluble to fluid, such as glass fragment, solid impurity etc.Along with the day by day attention of people to medicine and food quality, and perfect to medicine and food control system, standard and flow process of country, the foreign matter detection in the fluid products such as medicine, beverage day by day becomes requisite testing process.At present, in the production such as medicine, beverage and quality inspection real process, usually adopt the Manual light detection method, namely shine under condition at certain lamp, the testing staff directly observes bottled fluid product with human eye, checks in fluid product whether contain foreign matter, and contains foreign matter size, quantity etc.The method man power and material's input amount is large, and monitoring efficient and automaticity are low, and examination criteria is difficult to control adjustment.
formerly also exist a kind of automatic foreign body checking machine of dual signal reception (referring to utility model patent " automatic foreign body checking machine that dual signal receives " in technology, utility model patent number: ZL200720074851.6), be disposed with the luminotron assembly on light path in this device, light emission collecting lens, the light-receiving collecting lens, imaging lens, spectroscope, and the diaphragm and the optical receiving sensor array that arrange on two light splitting optical paths, utilize in light path diaphragm raising system to get signal to noise ratio (S/N ratio) and sensitivity, this device has advantages of certain, but Shortcomings still: utilize diaphragm raising system to get signal to noise ratio (S/N ratio) and sensitivity, it is limited that signal to noise ratio (S/N ratio) and sensitivity improve degree, in system, the optical receiving sensor array when receiving flashlight, also can receive external interference light, namely produces and measures noise, is subjected to external interference larger, and impact detects stability, optical system consists of complicated, and mechanical positioning requirements degree is high, simultaneously, is difficult to detect foreign matter, i.e. phase foreign body like light transmission features and fluid-phase of living in.
Summary of the invention
The object of the invention is to the deficiency for above-mentioned formerly technology, a kind of detection apparatus for phase foreign body in fluid is provided, have the characteristics such as sensitivity and signal to noise ratio (S/N ratio) are high, antijamming capability strong, the phase foreign body detection efficiency is high, simple and reasonable.
Basic conception of the present invention is: utilize phase-contrast technique and optical signal modulation demodulation techniques, after the light source assembly outgoing beam is modulated by signal generator, through beam shaping device, detected bottled fluid product, phase contrast imaging objective lens unit, photodetector array, the modulated beam of light that demodulator of PM signal PM collects photodetector array sees through signal and carries out the signal demodulation, obtains the information that detected bottled fluid product contains foreign matter.
Technical solution of the present invention is: comprise light source assembly, beam shaping device, phase contrast imaging objective lens unit, photodetector array, signal generator, demodulator of PM signal PM; Beam shaping device, phase contrast imaging objective lens unit, photodetector array are successively set on light source assembly outgoing beam light path, and detected bottled fluid product is arranged on light path between beam shaping device and phase contrast imaging objective lens unit; Photodetector array is arranged on looking like on the plane of phase contrast imaging objective lens unit; Light source assembly and demodulator of PM signal PM all are connected with signal generator; Demodulator of PM signal PM is connected with photodetector array.
Described light source assembly is a kind of of incoherent light source component, coherent source assembly, incoherent light source array, coherent source array, optical fiber source.
Described beam shaping device is a kind of of beam expander device, beam collimation device, beam collimation reshaper, beam expander reshaper.
Described phase contrast imaging objective lens unit is a kind of of phase contrast achromatic objective, phase contrast apochromatic objective, phase contrast flat field image-forming objective lens, phase contrast polarized light image-forming objective lens.
Described photodetector array is a kind of of photosensitive tube array, photodiode array, linear charge-coupled array, surface array charge-coupled device, linear array complementary metal-oxide-semiconductor transistor, face battle array complementary metal-oxide-semiconductor transistor, optics microchannel plate.
Described signal generator is a kind of of analog signal generator, digital signal generator, mixed type signal generator.
Described demodulator of PM signal PM is a kind of of analog signal demodulator, digital signal demodulator, software signal demodulation process module.
The course of work of apparatus of the present invention is: the light source assembly outgoing beam carries out the shaping collimation through beam shaping device; Signal generator is connected with light source assembly, the emission modulated drive signal is to light source assembly, the light source assembly outgoing beam is modulated, modulating frequency is avoided external interference light beats frequency and mains supply frequency, external interference light beats frequency is generally low frequency, less than 100Hz, in the present embodiment, selective light source component frequency modulating signal is 500Hz; Through the detected bottled fluid product of the modulated beam of light directive after the shaping collimation, collected by the phase contrast imaging objective lens unit through the transmission modulated beam of light of detected bottled fluid product, image on photodetector array; The phase contrast imaging objective lens unit has realized that the phase information of phase foreign body is to the conversion of amplitude information; Photodetector array is arranged on the picture plane of detected bottled fluid product through the imaging of phase contrast imaging objective lens unit, and the signal that photodetector array detects sees through signal for the modulated beam of light of detected bottled fluid product; Photodetector array is connected with demodulator of PM signal PM, will be detected bottled fluid product modulation optoelectronic information and be transferred to demodulator of PM signal PM, and the synchronous signal generator is connected with demodulator of PM signal PM, is transferred to demodulator of PM signal PM with reference to signal and is used for the signal demodulation; Demodulator of PM signal PM carries out the signal demodulation with the modulated beam of light of the detected bottled fluid product that photodetector array collects through signal, detecting frequency modulating signal is the signal of 500Hz, obtain the light transmission signal of detected bottled fluid product, the light transmission signal just can obtain the information such as foreign matter size, quantity, distribution in detected bottled fluid product by analysis.
The present invention has the following advantages and effect: compared with prior art, owing to having adopted modulation of source and photodetector array modulated signal analysis technology, improved sensitivity and signal to noise ratio (S/N ratio) that foreign matter detects; Suppress external interference light to the impact that device detects from principle, provide device to detect stability; And have system reasonable, simple in structure, realize that required expense is low, mechanical positioning requirements is low, use the characteristics such as operation is convenient; Adopted phase-contrast technique can test fluid in phase foreign body, monitoring efficient and highly sensitive.
Description of drawings
Fig. 1 is structural representation of the present invention.
Embodiment
The present invention is described in further detail below in conjunction with embodiment, and following examples are explanation of the invention, be reasonable application form of the present invention, and the present invention is not limited to following examples.
As Fig. 1, a kind of detection apparatus for phase foreign body in fluid comprises light source assembly 1, beam shaping device 2, phase contrast imaging objective lens unit 4, photodetector array 5, signal generator 6, demodulator of PM signal PM 7; Beam shaping device 2, phase contrast imaging objective lens unit 4, photodetector array 5 be successively on light source assembly 1 outgoing beam light path, and detected bottled fluid product is arranged on light path between beam shaping device 2 and phase contrast imaging objective lens unit 4; Photodetector array 5 is arranged on looking like on the plane of phase contrast imaging objective lens unit 4; Light source assembly 1 is connected with demodulator of PM signal PM and all is connected with signal generator 6; Demodulator of PM signal PM 7 is connected with photodetector array 5.
Light source assembly 1 adopts the incoherent light source array, beam shaping device 2 is the beam collimation reshaper, phase contrast imaging objective lens unit 4 adopts phase contrast flat field image-forming objective lens, photodetector array 5 is photodiode array, signal generator 6 adopts analog signal generator, demodulator of PM signal PM 7 adopts analog signal demodulator, and detected bottled fluid product 3 is the transparent medicine of injection, and phase foreign body is glass foreign.
The embodiment of the present invention course of work is that light source assembly 1 outgoing beam carries out the shaping collimation through beam shaping device 2; Signal generator 6 is connected with light source assembly 1, the emission modulated drive signal is to light source assembly 1, light source assembly 1 outgoing beam is modulated, modulating frequency is avoided external interference light beats frequency and mains supply frequency, external interference light beats frequency is generally low frequency, less than 100Hz, in the present embodiment, selective light source component 1 frequency modulating signal is 500Hz; Through the detected bottled fluid product 3 of the modulated beam of light directive after the shaping collimation, collected by phase contrast imaging objective lens unit 4 through the transmission modulated beam of light of detected bottled fluid product 3, image on photodetector array 5; The phase contrast imaging objective lens unit has realized that the phase information of phase foreign body is to the conversion of amplitude information; Photodetector array 5 is arranged on the picture plane of detected bottled fluid product 3 through 4 imagings of phase contrast imaging objective lens unit, and the signal that photodetector array 5 detects sees through signal for the modulated beam of light of detected bottled fluid product 3.
Photodetector array 5 is connected with demodulator of PM signal PM 7, to be detected bottled fluid product 3 modulation optoelectronic informations and be transferred to demodulator of PM signal PM 7, synchronous signal generator 6 is connected with demodulator of PM signal PM 7, is transferred to demodulator of PM signal PM 7 with reference to signal and is used for the signal demodulation; Demodulator of PM signal PM 7 carries out the signal demodulation with the modulated beam of light of the detected bottled fluid product 3 that photodetector array 5 collects through signal, detecting frequency modulating signal is the signal of 500Hz, obtain the light transmission signal of detected bottled fluid product 3, the light transmission signal just can obtain the information such as foreign matter size, quantity, distribution in detected bottled fluid product 3 by analysis.Stagger due to modulating frequency and external interference light beats frequency in the present invention, obviously suppress external interference light to the impact that device detects, improved sensitivity, signal to noise ratio (S/N ratio), and detect stability.
The invention provides a kind of detection apparatus for phase foreign body in fluid, utilize phase-contrast technique and modulation-demodulation technique, realized that successfully the phase foreign body in the fluid product detects, sensitivity and signal to noise ratio (S/N ratio) that foreign matter detects are high, discharge the impact that external interference light detects device, detected good stability; Have simultaneously reasonable in design, simple in structure, realize that required expense is low, mechanical positioning requirements is low, use the characteristics such as operation is convenient.

Claims (7)

1. detection apparatus for phase foreign body in fluid, comprise light source assembly, beam shaping device, phase contrast imaging objective lens unit, photodetector array, signal generator, demodulator of PM signal PM, it is characterized in that: beam shaping device, phase contrast imaging objective lens unit, photodetector array are successively set on light source assembly outgoing beam light path, and detected bottled fluid product is arranged on light path between beam shaping device and phase contrast imaging objective lens unit; Photodetector array is arranged on looking like on the plane of phase contrast imaging objective lens unit; Light source assembly and demodulator of PM signal PM all are connected with signal generator; Demodulator of PM signal PM is connected with photodetector array.
2. a kind of detection apparatus for phase foreign body in fluid as claimed in claim 1 is characterized in that: described light source assembly is a kind of of incoherent light source component, coherent source assembly, optical fiber source.
3. a kind of detection apparatus for phase foreign body in fluid as claimed in claim 1 is characterized in that: described beam shaping device is a kind of of beam expander device, beam collimation device, beam collimation reshaper, beam expander reshaper.
4. a kind of detection apparatus for phase foreign body in fluid as claimed in claim 1 is characterized in that: described phase contrast imaging objective lens unit is a kind of of phase contrast achromatic objective, phase contrast apochromatic objective, phase contrast flat field image-forming objective lens, phase contrast polarized light image-forming objective lens.
5. a kind of detection apparatus for phase foreign body in fluid as claimed in claim 1 is characterized in that: described photodetector array is a kind of of photosensitive tube array, photodiode array, linear charge-coupled array, surface array charge-coupled device, linear array CMOS transistor, face battle array CMOS transistor, optics microchannel plate.
6. a kind of detection apparatus for phase foreign body in fluid as claimed in claim 1 is characterized in that: described signal generator is a kind of of analog signal generator, digital signal generator, mixed type signal generator.
7. a kind of detection apparatus for phase foreign body in fluid as claimed in claim 1 is characterized in that: described demodulator of PM signal PM is a kind of of analog signal demodulator, digital signal demodulator, software signal demodulation process module.
CN 200910096073 2009-02-09 2009-02-09 Detection apparatus for phase foreign body in fluid Expired - Fee Related CN101482519B (en)

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EP2542879A1 (en) * 2010-03-02 2013-01-09 Koninklijke Philips Electronics N.V. Optical examinations with controlled input light
CN106198399B (en) * 2016-08-17 2023-10-27 远方谱色科技有限公司 Definition measuring device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101008616A (en) * 2006-01-23 2007-08-01 株式会社日立高新技术 Automatic analyzer
CN101131368A (en) * 2007-09-20 2008-02-27 上海市激光技术研究所 Automatic foreign body checking machine with double-photo signal receiving sensor array structure

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101008616A (en) * 2006-01-23 2007-08-01 株式会社日立高新技术 Automatic analyzer
CN101131368A (en) * 2007-09-20 2008-02-27 上海市激光技术研究所 Automatic foreign body checking machine with double-photo signal receiving sensor array structure

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JP特开平9-269299A 1997.10.14
贾榕凯.微分干涉相衬显微术得检测原理和方法.《仪器仪表与分析监测》.1988,(第2期),59-63. *

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