CN101411800A - Medicament for treating anxiety symptoms - Google Patents
Medicament for treating anxiety symptoms Download PDFInfo
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- CN101411800A CN101411800A CNA2008101595447A CN200810159544A CN101411800A CN 101411800 A CN101411800 A CN 101411800A CN A2008101595447 A CNA2008101595447 A CN A2008101595447A CN 200810159544 A CN200810159544 A CN 200810159544A CN 101411800 A CN101411800 A CN 101411800A
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Abstract
The invention discloses a medicine for treating anxiety neurosis. Tuckahoe , rhizima ligustici, rhizoma cyperi, semen zizyphi spinosae, rhizoma coptis, cinnamon, prepared rehmannia root, radix polygalae, mother-of-pearl, keel, carapax amydae and liquorice are used as raw materials; based on different characteristics of the traditional Chinese medicines, the traditional Chinese medicines in proportion are subjected to decoction, filtering, bottling and sterilization to prepare decoction by a routine method. The medicine is a traditional Chinese medicine preparation; according to a formula of traditional Chinese medicine theory, the medicine has reasonable material selection, tranquilizes, replenishes qi and addresses both the symptoms and root causes; and through the clinical observation of patients for many years, the medicine has remarkable curative effect for patients with anxiety neurosis caused by various reasons.
Description
Technical field the invention belongs to technical field of Chinese medicines, relates to a kind of medicine for the treatment of anxiety neurosis, is the Chinese patent medicine of feedstock production specifically with the Chinese herbal medicine.
The background technology anxiety neurosis is a common clinical, frequently-occurring disease.Have a strong impact on people's healthy and normal work and life.At present, the medicine of treatment anxiety neurosis is more, but mostly is Western medicine greatly.The medicine of western medicine anxiety neurosis is taken certain side effect for a long time, directly influences people's physical and mental health, directly brings spirit and burden economically for patient and family.
Summary of the invention the purpose of this invention is to provide a kind of medicine of the treatment anxiety neurosis of can stabilizing the emotions, having no side effect, to overcome the deficiencies in the prior art.
The objective of the invention is according to pathogenetic understanding and the Therapeutic Principle thereof of motherland's traditional medicine anxiety neurosis, with reference to modern pharmacological research, therefrom filter out the natural Chinese medicinal herb of the QI invigorating of calming the nerves, stabilizing the emotions, press the Chinese medical theory prescription, its performance is calmed the nerves separate hot-tempered effect.
Medicine of the present invention is the medicament of being made by the following weight proportion raw material
Poria 15g, Rhizoma Chuanxiong 12g, Rhizoma Cyperi 12g, Semen Ziziphi Spinosae 30g, Rhizoma Coptidis 6g, Cortex Cinnamomi 3g, Radix Rehmanniae Preparata 15g, Radix Polygalae 15g, Concha Margaritifera 30g, Os Draconis 20g, Carapax Trionycis 15g, Radix Glycyrrhizae 10
Above-mentioned each component is made Chinese medicine medicine decoction according to a conventional method, finishes by following step successively:
1) decoct: above-mentioned all medicines are put into marmite or rustless steel pressure cooker, add hydrology fire by the 1:2 of medicine total amount and decoct, boiled back 20 minutes, medicinal liquid is leached, the 1:1 by the medicine total amount adds the decoction of hydrology fire again, boils back 20 minutes, and medicinal liquid is leached;
2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrate mixing;
3) sterilization: the medicinal liquid bottle is put into pressure cooker sterilization 20 minutes, promptly get Chinese medicine medicine decoction of the present invention.
Medicine of the present invention is a Chinese medicine preparation, according to the theory of Chinese medical science prescription, select medicine rationally, the QI invigorating of calming the nerves, treating both the principal and secondary aspects of a disease, through clinical observation patient for many years, evident in efficacy, the anxiety neurosis patient that a variety of causes is caused has remarkable result.
Clinical drug of the present invention is taken the result and is shown, following advantage is arranged:
1, to select natural plant for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation, utilizes the comprehensive function treatment anxiety neurosis of the medicine of respectively distinguishing the flavor of, and no chemicals is nontoxic to human body, has no side effect, and is safe and reliable.
2, slow fire of the present invention is fried in shallow oil water, and effective ingredient scatters and disappears few, and the curative effect height is cheap, taking convenience, no any discomfort disease.
3, medicine of the present invention is obvious to the anxiety neurosis curative effect.
4, clinical drug of the present invention is observed, and can replace the medicine of other treatment anxiety neurosis.
For showing the therapeutic effect of medicine of the present invention to anxiety neurosis, the present invention is through the clinical observation of 1000 routine anxiety patient systems, and select medical history, the state of an illness, age, sex and anxiety patient 100 examples suitable to organize as a comparison with traditional therapy, wherein male 600 examples, woman's 400 examples, 18～60 years old age, course of disease February～10 year.Test group: the conventional medicine of stopping using, take medicine of the present invention; Matched group: take conventional medicine.Observation period is 1 month, checks after half a year, does not have recurrence and is produce effects, and sb.'s illness took a favorable turn is evident as effectively, and it is not obvious that sb.'s illness took a favorable turn is invalid.
Instructions of taking a: 50ml, 2 times on the one, warm water delivery service.Clinical realization the results are shown in Table 1.
Table 1: take medicine of the present invention (painstaking effort treasured) and take the observation of curative effect of conventional medicine to anxiety patient.
| Group | Case load | Produce effects (routine number) | Effectively (routine number) | Invalid (routine number) | Total effective rate (%) |
| Test group | 1000 | 478 | 522 | 0 | 100 |
| Matched group | 100 | 0 | 78 | 22 | 78.0 |
| T | 2.50 | 5.68 | 2.30 | 3.89 | |
| P | <0.05 | <0.05 | <0.05 | <0.05 | <0.05 |
As can be seen from Table 1, medicine of the present invention is obtained 478 examples that have of significant curative effect to 1000 routine anxiety patients, accounts for 47.8%; That takes a turn for the better has 522 examples, accounts for 52.2%; Total effective rate reaches 100%.
The specific embodiment
Take by weighing raw material by following proportioning:
Poria 15g, Rhizoma Chuanxiong 12g, Rhizoma Cyperi 12g, Semen Ziziphi Spinosae 30g, Rhizoma Coptidis 6g, Cortex Cinnamomi 3g, Radix Rehmanniae Preparata 15g, Radix Polygalae 15g, Concha Margaritifera 30g, Os Draconis 20g, Carapax Trionycis 15g, Radix Glycyrrhizae 10g
Above-mentioned each component is made Chinese medicine medicine decoction according to a conventional method, finishes by following step successively:
1) decoct: above-mentioned all medicines are put into marmite or rustless steel pressure cooker, add hydrology fire by the 1:2 of medicine total amount and decoct, boiled back 20 minutes, medicinal liquid is leached, the 1:1 by the medicine total amount adds the decoction of hydrology fire again, boils back 20 minutes, and medicinal liquid is leached;
2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrate mixing;
3) sterilization: the medicinal liquid bottle is put into pressure cooker sterilization 20 minutes, promptly get Chinese medicine medicine decoction of the present invention.
Model case
Case 1: Huang, the woman, 16 years old, because of insomnia, felt restless 6 months, examine on March 18th, 2008, the patient rose up into an emphasis senior middle school before half a year, and began to board at school, because homework is more, and difficulty than junior middle school's height a lot, the back quiz is finished in the unit, and several subjects are arranged is not very good, and psychological burden is heavier for this reason, insomnia gradually occurs, nervous, uneasy in either sitting or lying, and sense is nervous, perspire, feverish sensation over the palm, and frequent micturition, and the diarrhoea phenomenon is arranged, attention can not be concentrated on class gradually, school grade descends, gradually can not adhere to normal school work, be forced to go home have a rest, so the head of a family looks after children institute to go to a doctor.The patient physically well develops since the childhood, is conscientious in one's work, and individual character is eager to do well in everything.Diagnosis: anxiety neurosis.Family members consider that child's age is less, worry that the Western medicine side effect is big, propose to use treatment by Chinese herbs, housecoat medicine oral liquid of the present invention, and cooperate the psychotherapy, alleviate fully after January, and recovered normal school work, go back to the school later in order, school grade makes rapid progress, and the teacher and the head of a family feel quite pleased.
Case 2: Jiao, the man, 46 years old, because of lather, the dying sense of paroxysmal 1 year, come institute to go to a doctor on October 18th, 2007, insomnia appears in patient no bright reason ground before 1 year, the emotion agitation, emotional, often feel the body skin heating, palm of the hand arch of the foot is perspired, and dyspnea appears in paroxysmal, with a kind of dying sense, A great misfortune has come for sensation, panic nervous, repeatedly make a call to 120 emergency calls, do not find that to examination in hospital other are unusual except that tachycardia, similar outbreak was no less than 3～4 times in every month, once arrived county people's hospital, municipal hospital checks and does not find tangible physical disease, goes to a doctor in county mental hospital and considers that panic attack gives Pa Lexiting, Propranolol, the Drug therapy state of an illness such as buspirone take a turn for the better to some extent, but unstable, patient seeks medical advice many places, all the time do not heal, come institute to go to a doctor on October 18th, 2007, diagnosis: anxiety neurosis companion panic attack, take medicine oral liquid of the present invention, cooperate the psychotherapy, be in hospital February, the state of an illness is alleviated, be in after leaving hospital and continue to take the after treatment in 1 month of invention medicine oral liquid, and institute's psychological counselling regularly, present stable disease, each side is in order.
Case 3: Korea Spro so-and-so, the woman, 56 years old, because of uncomfortable 3 years of nervous, body, increase the weight of January, examine on July 13rd, 2007.The patient is terminally ill because of the husband before 3 years, worry about for this reason, insomnia gradually appears, the emotion agitation, emotional, time sense is uncomfortable in chest, nervous, perspire, scorching, and the sense whole body is numb, check repeatedly to general hospital, do not find obvious physical disease, the doctor considers that the neurasthenia gives black pigment used by women in ancient times to paint their eyebrows and calms the nerves, oryzanol, the Drug therapy state of an illness such as diazepam once made moderate progress, but the state of an illness is not alleviated, it is heavy when time thes be light, successively to the mental hospital's diagnosis and treatment of several institutes, curative effect is dissatisfied, and worries drug dependence, examine on July 13rd, 2007, diagnosis: anxiety neurosis, take medicine oral liquid of the present invention, cooperate psychotherapy 80 days, the state of an illness is alleviated, As-Is is good, is in and can be engaged in routine matter, and the household is very satisfied.
Case 4: the king so-and-so, the woman 41 years old, because of nervous, irritated, irritability 1 year, the dying sense of paroxysmal June, examines on January 11st, 2007.The patient pondered over more because of the marriage setback before 1 year, insomnia gradually appears, the mood agitation, sensation What for thing all can not be got down, often occur uncomfortable in chest, nervous, perspire, the urgent micturition frequent micturition, diarrhoea, menoxenia, conjugal relation is improved before half a year, it is stable that family recovers, but above symptom does not slow and separates, and the paroxysmal rapid breathing appears, feel to be faced with imminent disaster, satisfy to local municipal hospital and check, remove tachycardia and do not find other tangible body problems, the doctor tells that the patient is that spirit is too nervous, and the suggestion patient sees shrink, and the patient queries this, just in time do not go to a doctor, soon analogue is shown effect once more, and frequency is more and more diligent, gives diazepam to emergency treatment prescription on individual diagnosis Shi doctor, oryzanol, Drug therapys such as Propranolol, make moderate progress, therefore patient relies on the diazepam Drug therapy fully, and dosage is increasing, comes institute to go to a doctor on January 11st, 2007, diagnosis: anxiety neurosis companion panic attack, it is longer that the consideration patient takes the diazepam time, gives trazodone and substitute, and takes medicine oral liquid of the present invention simultaneously, treated 65 days, the state of an illness is alleviated, and As-Is is stable, and adheres to work, family harmony, family members are very satisfied.
Case 5: Lee, the man 37 years old, because of lather, insomnia 1 year, comes institute to go to a doctor on April 26th, 2007.The emotion agitation appearred in the patient because of operating pressure is bigger before 1 year, depressed, that feels anxiety all day does not know that What for is good, often make mistakes, fear that the leader blames, sometimes feel to get a swelled head, uncomfortable in chest, nervous, perspire, extremity are numb, the urgent micturition frequent micturition, have difficulty in going to sleep night, gradually work lacked confidence, increases the weight of closely over the past half year, susceptible to lose temper due to restlessness, sometimes crash office articles, sensation work can't be competent at, the rest of have to asking for leave, once repeatedly arrived the general hospital inspection, all do not find obvious abnormal results, the doctor gives amitriptyline, diazepam, the treatment of medicines such as buspirone is because of side effect fails more greatly to adhere to taking, the state of an illness commentaries on classics of not getting better, come institute to go to a doctor on April 26th, 2007, diagnosis: anxiety neurosis, take medicine oral liquid of the present invention then, cooperate 70 days state of an illness of psychotherapy to alleviate simultaneously, and institute's check regularly, As-Is is stable, adheres to operate as normal always.
Claims (1)
1, a kind of Chinese medicine medicine for the treatment of depression is characterized in that it is the decoction of being made by the following weight proportion raw material: Poria 15g, Rhizoma Chuanxiong 12g, Rhizoma Cyperi 12g, Semen Ziziphi Spinosae 30g, Rhizoma Coptidis 6g, Cortex Cinnamomi 3g, Radix Rehmanniae Preparata 15g, Radix Polygalae 15g, Concha Margaritifera 30g, Os Draconis 20g, Carapax Trionycis 15g, Radix Glycyrrhizae 10; Its preparation method is finished by following step successively: 1) decoct: above-mentioned all medicines are put into marmite or rustless steel pressure cooker, 1:2 by the medicine total amount adds the decoction of hydrology fire, boiled back 20 minutes, medicinal liquid is leached, 1:1 by the medicine total amount adds the decoction of hydrology fire again, boiled back 20 minutes, medicinal liquid is leached; 2) bottling: seal in the disinfectant bottle in advance with packing into behind twice filtrate mixing; 3) sterilization: the medicinal liquid bottle is put into pressure cooker sterilization 20 minutes, get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101595447A CN101411800B (en) | 2008-12-01 | 2008-12-01 | Medicament for treating anxiety symptoms |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101595447A CN101411800B (en) | 2008-12-01 | 2008-12-01 | Medicament for treating anxiety symptoms |
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| Publication Number | Publication Date |
|---|---|
| CN101411800A true CN101411800A (en) | 2009-04-22 |
| CN101411800B CN101411800B (en) | 2010-12-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008101595447A Expired - Fee Related CN101411800B (en) | 2008-12-01 | 2008-12-01 | Medicament for treating anxiety symptoms |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105381015A (en) * | 2015-11-26 | 2016-03-09 | 天津中医药大学 | Traditional Chinese medicine composition with anti-depression function and preparation method thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552436B (en) * | 2012-01-10 | 2014-05-07 | 上海市中医医院 | Medicine for treating anxiety and depressive disorder as well as application of medicine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1283312C (en) * | 2002-09-05 | 2006-11-08 | 南京大学 | Antidepressant composition and preparing process thereof |
| CN1317027C (en) * | 2005-02-21 | 2007-05-23 | 李有田 | Chinese medicine for treating depression |
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2008
- 2008-12-01 CN CN2008101595447A patent/CN101411800B/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105381015A (en) * | 2015-11-26 | 2016-03-09 | 天津中医药大学 | Traditional Chinese medicine composition with anti-depression function and preparation method thereof |
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| Publication number | Publication date |
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| CN101411800B (en) | 2010-12-29 |
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| CB03 | Change of inventor or designer information |
Inventor after: Chen Decai Inventor after: Li Delu Inventor after: He Ling Inventor after: Li Xiangming Inventor after: Wang Yingqun Inventor after: Ren Zhiyun Inventor before: Tang Zhenkun Inventor before: Chen Decai Inventor before: He Ling Inventor before: Li Xiangming Inventor before: Wang Yingqun Inventor before: Ren Zhiyun |
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| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: TANG ZHENKUN CHEN DECAI HE LING LI XIANGMING WANG YINGQUN REN ZHIYUN TO: CHEN DECAI LI DELU HE LING LI XIANGMING WANG YINGQUN REN ZHIYUN |
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| C14 | Grant of patent or utility model | ||
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20101229 Termination date: 20111201 |